Claims
- 1. A packing for high speed liquid chromatography prepared by the process which comprises suspending in water a mixture consisting of 65 to 90 parts by weight of at least one monovinylbenzene, 35 to 10 parts by weight of at least one polyvinylbenzene, the total amount of the monovinylbenzene and polyvinylbenzene being 100 parts by weight, and 30 to 200 parts by weight of a solvent capable of dissolving polystyrene, and free radical-polymerizing the monovinylbenzene and the polyvinylbenzene in suspension, said polymerizaton being carried out in the presence of 0.1 to 5.0 parts by weight of at least one free radical polymerization initiator having a half-life period of about 2 to 60 minutes at 70.degree. C., and in such a manner that at least until the polymerization conversion reaches 50%, the polymerization is effected at a temperature at which the half-life period of the polymerization initiator is in the range of about 5 to 120 minutes to thereby provide a microporous, granular cross-linked monovinylbenzene-polyvinylbenzene copolymer having a volume average particle diameter of about 2 to 50 micrometers, an exclusive molecular weight for polystyrene of about 500 to 20,000, and the weight percent (X) of polyvinylbenzene units based on the total monomeric units in the copolymer and the gradient (.alpha.) of the calibration curve of the polystyrene are defined by the region bounded by and including the following three lines in rectangular coordinates (.alpha., X): ##EQU11##
- .alpha.=2.5
- X=35.
- 2. The packing of claim 1 wherein the polymerization initiator is 2,2'-azobis(2,4-dimethylvaleronitrile) or diisopropyl peroxydicarbonate.
- 3. The packing of claim 1 wherein the polymerization initiator is 2,2'-azobis(2,4-dimethylvaleronitrile) and at least until the polymerization conversion reaches 50%, the polymerization is carried out at a temperature of about 65.degree. to 85.degree. C.
- 4. The packing of claim 1 wherein the polymerization initiator is diisopropyl peroxydicarbonate and at least until the polymerization conversation reaches 50%, the polymerization is carried out at a temperature of about 60.degree. to 80.degree. C.
- 5. The packing of claim 1 wherein said at least one monovinylbenzene is styrene and said at least one polyvinylbenzene is divinylbenzene.
- 6. The packing of claim 1 wherein said polymerization initiator is selected from the group consisting of 2,2'-azobis(4-methoxy-2,4-dimethylvaleronitrile), 2,2'-azobis(2,4-dimethylvaleronitrile), isobutyryl peroxide, diisopropyl peroxydicarbonate, and di-2-ethylhexyl peroxydicarbonate.
- 7. The packing of claim 1 wherein the weight % (X) and the gradient (.alpha.) are defined by the region bounded by and including the following three lines in rectangular coordinates (.alpha.,X): ##EQU12##
- .alpha.=3
- X=27.
- 8. The packing of claim 1, wherein the weight % (X) and the gradient (.alpha.) are defined by the region bounded by and including the following four lines in rectangular coordinates (.alpha.,X): ##EQU13##
- .alpha.=4.4
- X=27
- X=35.
- 9. The packing of claim 1, wherein said copolymer has a volume average particle diameter of about 5 to 30 .mu.m.
- 10. The packing of claim 1, wherein said exclusive molecular weight is from about 1,500 to 12,000.
- 11. The packing of claim 1 having a toluene regain of about 0.5 to 2.5 m/g.
- 12. The packing of claim 1, wherein said copolymer is a styrene-divinylbenzene-based copolymer.
- 13. The packing of claim 1 wherein said mixture suspended in water consists of about 65 to 80 parts by weight of at least one monovinylbenzene, about 35 to 20 parts by weight of at least one polyvinylbenzene, the total amount of the monovinylbenzene and the polyvinylbenzene being 100 parts by weight, and 80 to 150 parts by weight of the solvent capable of dissolving polystyrene.
- 14. The packing of claim 1 wherein the solvent capable of dissolving polystyrene is toluene.
- 15. The packing of claim 1 wherein said polymerization initiator having a half-life of 2 to 60 minutes at 70.degree. C. makes up at least 60% by weight of the total polymerization initiator.
Priority Claims (2)
Number |
Date |
Country |
Kind |
53-110211 |
Sep 1978 |
JPX |
|
53-156292 |
Dec 1978 |
JPX |
|
Parent Case Info
This is a continuation, of application Ser. No. 74,028, filed Sept. 10, 1979, abandoned.
US Referenced Citations (3)
Continuations (1)
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Number |
Date |
Country |
Parent |
74028 |
Sep 1979 |
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