Claims
- 1. A method for inducing cells to replicate, differentiate, transdifferentiate and or form primoridia in vitro and or tissues or organs in vivo comprising:
a) extracting at least one Signal-plex from a tissue or tissue-specific microparticulates; b) optionally inducing cells in vitro or in vivo with said Signal-plex to replicate, differentiate, transdifferentiate, and or form specific tissues and or organs; and c) optionally culturing said cells having said Signal-plex with at least one scaffold in vitro to form primordia in vitro and or said tissues or organs in vivo after implantation of said primordia; and
- 2. The method of claim 1, wherein said inducing further comprises testing the specificity of said Signal-plex by cells selected from the group consisting of stem cells, cells which may have latent stem cell properties and cells which may be capable of undergoing transdifferentiation.
- 3. The method of claim 1, further comprising:
a) delivering said Signal-plex to tissues or organs of a recipient after extracting said Signal-plex.
- 4. The method of claim 3, wherein said delivering is by means of injection.
- 5. The method of claim 1, further comprising:
a) adding said Signal-plex to a carrier after extracting said Signal-plex; and b) delivering said carrier to tissues or organs of a recipient.
- 6. The method of claim 1, further comprising:
a) adding said cells having said Signal-plex attached to said scaffold to a carrier; b) delivering said carrier to tissues or organs of a recipient. delivering comprises topically applying said carrier onto said tissue or organ of said recipient.
- 20. The method of claim 5, wherein said carrier is selected from the group consisting of a salve, an ointment and an emollient; and, wherein said delivering comprises topically applying said carrier onto said tissue or organ of said recipient.
- 21. The method of claim 1, further comprising using said Signal-plex as a pharmaceutical agent by delivering said Signal-plex or said scaffold with or without the use of a carrier to a recipient.
- 22. The method of claim 21, wherein said delivering is by means of injection.
- 23. The method of claim 1, further comprising using said Signal-plex to induce wound healing by delivering said Signal-plex or said scaffold with or without the use of a carrier to a wound of a recipient.
- 24. A pharmaceutical agent produced by the method of claim 1.
- 25. A topical agent produced by the method of claim 1.
- 26. A carrier comprising at least one Signal-plex produced by the method of claim 1.
- 27. A carrier comprising cells having a Signal-plex attached to a scaffold produced by the method of claim 1.
- 28. Specific cells differentiated or transdifferentiated by the method of claim 1.
- 29. Specific tissues or organs formed by the method of claim 1.
- 30. A scaffold comprising specific cells or primordia produced by the method of claim 1.
- 31. The method of claim 1, wherein said Signal-plex induces histiogenesis and organogenesis in vitro and or in vivo in animals.
- 32. The method of claim 1, wherein said Signal-plex induces differentiation, transdifferentation, and or said cells to stimulate formation of specific tissues and or organs of the body.
- 33. A composition comprising scaffold(s), signaling complex(es) and stem cells.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is related to co-pending U.S. Application No(s). 60/256,614, filed Dec. 18, 2000, 60/256,593, filed Dec. 18, 2000 and 60/251,125 (from which it claims priority), filed Dec. 4, 2000, and a U.S. Application filed concurrently, entitled “Use of Stem Cells Derived from Fetal Skin,” the entire contents of which are incorporated herein by reference.
Provisional Applications (3)
|
Number |
Date |
Country |
|
60256614 |
Dec 2000 |
US |
|
60256593 |
May 2001 |
US |
|
60251125 |
Dec 2000 |
US |