Generation of human cytomegalovirus yeast artificial chromosome recombinants

BACKGROUND OF THE INVENTION

Human cytomegalovirus (HCMV) is the leading cause of viral congenital infections worldwide, involving about 1% of newborns. In children, the consequences may be severe, especially in case of maternal primary infection during pregnancy. In the United States, about 30,000 to 40,000 newborns are affected each year; more than 9,000 of these children are left with permanent neurological sequelae. Demmler, G. J., 1994, Congenital cytomegalovirus infection,

Semin. Pediatr. Neurol.

1(1):36-42. The annual cost of treating cytomegalovirus infection complications in the United States is about two billion dollars. Daniel Y. et al., 1995, Congenital cytomegalovirus infection,

Eur. J. Obstet. Gynecol. Reprod. Biol.,

63(1):7-16.

HCMV is a species-specific member of the herpes virus family. Other well-known members of the herpes virus family include herpes simplex virus, types I and II, Epstein-Barr virus and Varicella Zoster virus. Although these viruses are related to each other taxonomically as double-stranded DNA viruses, infections due to these viruses manifest in a clinically distinct manner. In the case of HCMV, medical conditions arising from congenital infection include jaundice, respiratory distress, and convulsive seizures which may result in mental retardation, neurologic disability or death. As noted above, congenital HCMV infection produces significant problems from both personal and public health perspectives.

Infection in adults is frequently asymptomatic, but may manifest as mononucleosis, hepatitis, pneumonitis, or retinitis. HCMV infection is particularly significant in immunocompromised patients such as AIDS sufferers, chemotherapy patients, and organ transplant patients undergoing tissue rejection therapy.

The mechanisms of HCMV pathogenesis are not fully understood. It is believed that host factors, such as cellular and/or humoral immune responses might be involved. See, Alford and Britt, “The Human Herpesviruses”, Eds. Roizman, B., R. J. Whitley and C. Lopez, Raven Press, N.Y., 1993, pp 227-55. It has also been speculated that genetic variability (either structural or antigenic or both) among different strains of HCMV could be responsible for the variability in clinical manifestations observed. See, Pritchett, R. F., 1980, DNA nucleotide sequence heterogeneity between the Towne and AD169 strains of cytomegalovirus,

J. Virol.

36(1):152-61; Lehner, R. et al., 1991, Comparative sequence analysis of human cytomegalovirus strains,

J. Clin. Microbiol.

29(11):2494-502; Fries, B. C., 1994, Frequency distribution of cytomegalovirus envelope glycoprotein genotypes in bone marrow transplant recipients,

J. Infect. Dis.

169(4):769-74.

Classical drug therapies have generally focused upon interactions with proteins in efforts to modulate their disease causing or disease potentiating functions. Such therapeutic approaches have failed for cytomegalovirus infections.

Effective therapy for HCMV has not yet been developed despite studies on a number of antiviral agents. Interferon, transfer factor, adenine arabinoside (Ara-A), acycloguanosine (Acyclovir, ACV), and certain combinations of these drugs have been ineffective in controlling HCMV infections. Based on preclinical and clinical data, foscarnet (PFA) and ganciclovir (DHPG) show limited potential as antiviral agents. PFA treatment has resulted in the resolution of HCMV retinitis in five AIDS patients to date. DHPG studies have shown efficacy against HCMV retinitis and colitis. DHPG seems to be well tolerated by most treated individuals, but the ppearance of a reversible neutropenia, the emergence of resistant strains of HCMV upon long-term administration, and the lack of efficacy against HCMV pneumonitis limit the long term applications of this compound.

Immunoglobulin has also been utilized for treating HCMV infections. See, Condie, R. M. et al., 1984, Prevention of cytomegalovirus infection in bone marrow transplant recipients by prophylaxis with an intravenous, hyperimmune cytomegalovirus globulin,

Birth Defects,

20:327-344; Perrillo, R. P. et al., 1987, Immune globulin and hepatitis B immune globulin,

Arch. Intern Med.,

144:81-85; Snydman, D. R., et al. 1987, Use of cytomegalovirus immune globulin to prevent cytomegalovirus disease in renal-transplant recipients,

N. Engl. J. Med.,

317:1049-1054. The development of more effective and less-toxic therapeutic compounds and methods is needed for both acute and chronic use.

Several HCMV vaccines have been developed or are in the process of development. Vaccines based on live attenuated strains of HCMV have been described. See, Plotkin, S. A. et al., 1984,

Lancet,

1:528-30; Plotkin, S. A. et al., 1976,

J. Infect. Dis.,

134:470-75; Glazer, J. P. et al., 1979,

Ann. Intern. Med.,

91:676-83; and U.S. Pat. No. 3,959,466. A proposed HCMV vaccine using a recombinant vaccinia virus expressing HCMV glycoprotein B has also been described. Cranage, M. P. et al., 1968

EMBO J.,

5:3057-3063. However, vaccinia models for vaccine delivery are believed to cause local reactions. Additionally, vaccinia vaccines are considered possible causes of encephalitis.

Adenoviruses have been developed previously as efficient heterologous gene expression vectors. For example, an adenovirus vector has been employed to express herpes simplex virus glycoprotein gB (Johnson, D. C. et al., 1988,

Virol.,

164:1-14), human immunodeficiency virus type 1 envelope protein (Dewar, R. L. et al., 1988,

J. Virol.,

63:129-136), and hepatitis B surface antigen (Davis, A. R. et al, 1985,

Proc. Natl. Acad. Sci., U.S.A.,

82:7560-7564; Morin, J. E. et al., 1987,

Proc. Natl. Acad. Sci., U.S.A.,

84:4626-4630). Adenoviruses have also been found to be non-toxic as vaccine components in humans (Takajuji, E. T. et al., 1970,

J. Infect. Dis.,

140:48-53; Collis, P. B. et al., 1973,

J. Inf. Dis.,

128:74-750; and Couch, R. B. et al., 1963,

Am. Rev. Respir. Dis.,

88:394-403). U.S. Pat. Nos. 5,591,439 and 5,552,143 provide novel vaccine components for HCMV which comprise an adenovirus expression system capable of expressing a selected HCMV subunit gene in vivo.

Human CMV is a large, enveloped herpesvirus whose genome consists of a double-stranded DNA molecule approximately 240,000 nucleotides in length. This genome is the most complex of all DNA viruses and is approximately 50% larger than the genome of herpes simplex virus (HSV). Intact viral DNA is composed of contiguous long (L) and short (S) segments, each of which contains regions of unique DNA sequence flanked by homologous regions of repetitive sequence. As a group, human CMV isolates share at least 80% sequence homology, making it nearly impossible to classify cytomegaloviruses into subgroups or subtypes, although variations in the restriction endonuclease patterns of various CMV DNA preparations are identifiable in epidemiologically unrelated strains. The DNA of the prototypic strain of CMV (AD 169) has been sequenced and reported to contain a conservative estimate of 175 unique translational open reading frames (ORFs). A number of the predicted CMV gene products show homology to other human herpesvirus gene products.

The large genome of CMV is difficult to manipulate. Cloning and mutagenesis of murine CMV (MCMV) has been accomplished using a bacterial artificial chromosome (“BAC”). See, Messerle, et al. 1997, Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome.

Proc. Natl. Acad. Sci. U.S.A.,

94: 14759-14763. Cloning of MCMV in a BAC allows for manipulation of the CMV genome within the bacterial system. Another useful vector, the yeast artificial chromosome (“YAC”) has been utilized to clone an infectious adenovirus (Ketner et al., 1994,

Proc. Natl. Acad. Sci. U.S.A.

91:6180-6190). However, it has not yet been demonstrated that the CMV genome could be successfully cloned into and manipulated within a yeast artificial chromosome (“YAC”).

Yeast artificial chromosomes (YACs) allow the propagation of very large segments of exogenous DNA in a microbial organism that is easy to work with and grow (Schlessinger, D. 1990, Yeast artificial chromosomes: tools for mapping and analysis of complex genomes,

Trends In Genetics

6:248-253). The great promise that YAC technology holds for studies of gene function and regulation has been strengthened by the development of methods for transferring YACs into mammalian cells and animals (Choi, T. K. et al., 1993, Transgenic mice containing a human heavy chain immunoglobulin gene fragment cloned in a yeast artificial chromosome.

Nature Gen.

4:117-123).

YAC transgenic approaches are very powerful and are greatly enhanced by the ability to efficiently manipulate the cloned DNA. A major technical advantage of yeast is the ease with which specific genome modifications can be made via DNA-mediated transformation and homologous recombination. In particular, an alternative recombinant cloning method of YAC construction has recently been described (Ramsay, M. 1994, Yeast artificial chromosome cloning.

Mol. Biotech.

1:181-201. The method involves co-transformation of a target DNA, such as the HCMV viral genome, with YAC vector arms containing appropriate DNA segments homologous to the target DNA. Recombination in the yeast cell then generates the desired YAC. A schematic of this procedure is shown in FIG.

1

.

The present invention provides a YAC vector that includes the full-length DNA sequence of the CMV virus. This vector provides a solution to the long-felt need for a CMV vaccine, and provides a tool for studying the replication of CMV using cell-line models.

SUMMARY OF THE INVENTION

The present invention provides a YAC vector that includes portions of and full-length DNA sequence of the CMV virus. This vector provides a solution to the long-felt need for a CMV vaccine, and provides a tool for studying the replication of CMV using cell-line models.

The present invention provides recombinant DNA constructs and YAC vectors comprising, in certain embodiments, overlapping segments of the HCMV genome. In other embodiments, the present invention provides a recombinant DNA constructs and YAC vectors comprising the entire CMV genome. This invention provides stable partial and full length YAC-HCMV clones useful for studying CMV replication, generating CMV virus and constructing CMV vaccines.

In general, the present invention provides an isolated recombinant DNA molecule comprising a yeast artificial chromosome, including at least a portion of HCMV genome. In preferred embodiments the DNA molecule further comprises at least one a sequence. Preferably the HCMV genome is derived from the Towne strain or from the AD169 strain. In preferred embodiments, the recombinant DNA molecule comprises a DNA molecule selected from the group consisting of Y1-2, Y3-2, Y2-4, Y4-7 and Y5-26, described in Table 2, below. In another embodiment, the invention provides a composition suitable for use as a vaccine comprising the isolated recombinant DNA molecule and a pharmaceutically acceptable excipient.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1

shows recombinant targeted cloning. A mixture of the two YAC vector arms (derived from linearized plasmids that carry targeting segments represented by black boxes) and the HCMV genome (the target DNA) are simultaneously introduced into transformation competent yeast. Homologous recombination in the yeast cell amongst these DNAs results in the formation of a specific YAC clone.

FIG. 2

shows plasmid maps of pRML1(AB) and pRML2(AB) derived from pRML1 and pRML2 targeting vectors.

FIG. 3

shows an example of a pulse-field gel analysis of two yeast strains carrying different YAC-HCMV recombinants; Y5-26, lane 2; Y2-4, lane 3; and control yeast without YAC, lane 4. Left panel: the ethidium bromide-stained gel. Right panel: a Southern blot probed with STS5. The positions of the 50 kb marker (lane 1) are shown, and the YAC-HCMV DNAs are marked. Note, Y5-26 co-migrates with the yeast chromosome (VI) of ˜290 kb.

FIG. 4

shows a schematic diagram of YAC-HCMV clones spanning the entire viral genome.

FIG. 5

shows the transfer of Y5-26 to human foreskin fibroblast (HFF) cells, including Sequence Tagged Site (STS) analysis for the integrity of the transferred genome. M stands for the marker lane. Lane V shows viral (HCMV, Towne) injected HFF cells. Lane Y shows YAC 5-26 transferred cells. Lane (..) shows mock transferred cells. Representive STSs (1, 4, 5, 8, 12, 14, 16, 19, and 20) are shown.

FIG. 6A

shows transient transfection assays using 1 μg DNA of the plasmids described, followed by infection with HCMV at a multiplicity of infection (M.O.I.) of 10. NIH 3T3 cells were lysed at different times post infection, or at the moment of infection (mock), and the luciferase activity of the extracts was measured. The relative luciferase activity of a typical experiment is shown, where triplicate measurements were taken. The relative light units (rlu) at each time post infection are normalized to the activity in the corresponding mock-infected cells.

FIG. 6B

shows stably transfected clones were infected with HCMV at an M.O.I. of 10, and samples were taken at different times post infection. The average rlu values from at least two experiments in triplicate are shown. Clones 2A-1, 2A-3 and 2A-5 are three representative clones stably transfected with pLHN.UL54wt. Clones 6A-1, 6A-2 and 6A-4 are representative clones stably transfected with pLHN.UL86.

FIG. 7

shows structure of an HCMV's genome, with the Unique Long Region (UL), Unique Short Region (US), and the inverted and direct repetitive sequences. The STS panel shows the relative positions of the pairs of oligonucleotides used to check the integrity of HCMV. Five YACs are shown, with their corresponding mutations outlined. The selectable markers are shown (U, URA3; T, TRP1; L, LEU2; P, puromycin resistance; Neo, neomycin resistance), as well as the positions of the HCMV sequences where the mutations were performed.

FIG. 8A

shows Pulse Field Gel Electrophoresis in which different DNA samples were resolved: size markers (lane 1), YPH857 (lanes 2 and 4), Y24 (lanes 3, 5 and 6) and Y24P (lane 7). The gels were either stained with ethidium bromide (lanes 1 to 3), or hybridized to a UL54 specific probe (lanes 4 and 5, named pol) or to a puromycin specific probe (lanes 6 and 7, named puro). The sizes of the marker DNA fragments are shown in kilobases. The arrows indicate the band corresponding to either Y24 or Y24P.

FIG. 8B

shows an agarose gel in which an aliquot of the STS PCR reaction was loaded. The lanes are named V for AD169 DNA or Y for YAC DNA. The set number for the corresponding STS is indicated, as well as the location of the size markers.

FIG. 8C

shows PCR reactions to test the UL54-Luc and UL86-Luc mutations, and their integration in the correct position in Y24P. Specific primers were used, YAC54.2 and GLprimer2 (lanes 1 to 3) YAC86.2 and GLprimer2 (lanes 4 and 5). The DNA samples are Y24P (lanes 1 and 4), Y24P/UL54wt-Luc (lane 2), Y24P/UL54IRM-Luc (lane 3), and Y24P/UL86-Luc (lane 5).

FIG. 9A

shows Y24P/UL54wt-Luc transgenic lines were infected with HCMV at an M.O.I. of 10. Samples were harvested at the indicated times post infection. Averages of at least two experiments in triplicate are shown. As a negative control, Y24P/UL86-Luc clones (5C and 7E) were used.

FIG. 9B

shows fold activation in luciferase activity in transgenic plasmid H) pLHN.UL54wt lines (2A-1, 2A-3 and 2A-5) and Y24P/UL54wt-Luc lines (31C, 42.8 44.11).

FIG. 10

shows STS analysis of the YAC transgenic NIH 3T3 clones. PCR rections were performed using specific primer sets designed along the HCMV genome. DNA from either NIN 3T3 cells (lanes 1, 4, 7, 10, 13), yeast Y24P positive control (lanes 2, 5, 8, 11, 14) or NIH 3T3/Y24P/UL54wt-luc 44.11 clone (lanes 3, 6, 9, 12, 15) was used, along with different sets of oligos (STS), indicated in the top part of the figure.

FIG. 11

shows the stable NIH 3T3 clone Y24P/UL54wt-Luc 44.11 was infected with HCMV, at different M.O.I. from 0.005 to 10. Cells were harvested at 48 hours post-infection, and the luciferase activity was measured. Each point represents the average of two independent infections.

FIG. 12

shows stable Y24P/UL54IRM-Luc NIH 3T3 clones were infected with HCMV at a M.O.I. of 10. Samples were harvested at the indicated times and the luciferase activity determined. Each point represents the average of at least two independent experiments in triplicate. The fold activation was calculated dividing the absolute value by the mock-infected value. Three representative clones are shown.

FIG. 13

shows Y24P/UL54wt-Luc NIH 3T3 clones were infected with MCMV at a M.O.I. of 10. Samples were harvested at the indicated times and the luciferase activity measured. Each point represents the average of at least two independent experiments in triplicate. The fold activation was calculated dividing the absolute value by the mock-infected value. Two representative clones are shown.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

Polynucleotides of the Invention

The present invention provides a vector comprising at least a portion and up to substantially all of a full-length CMV genome on a single nucleic acid molecule that is capable of replicating in a host cell such as a yeast cell. Preferably, the CMV genome is a human CMV (HCMV), murine CMV (MCMV), or guinea pig CMV (gpCMV) genome. In a preferred embodiment, the CMV genome is incorporated into a yeast artificial chromosome (“YAC”). The YAC supplies cis-genetic elements that permit maintenance of the YAC in yeast cells (telomeres, a centromere, and origins of replication). The YAC can also supply genetic markers used to select yeast cells containing a YAC. In one embodiment, a YAC-CMV vector is provided that incorporates portions of the pRML1 and pRML2 targeting vectors including conditional centromere and the herpes simplex virus thymidine kinase gene under the control of the yeast DED1 promoter and derived from pCGS966, permitting amplification of the YAC by growth in selective medium as described previously (Spencer, F. et al., 1993, Targeted recombination-based cloning and manipulation of large DNA segments in yeast,

Methods in Enzymology.

5:161-175; Hieter, P. et al., 1990, Yeast artificial chromosomes: Promises kept and pending,

Genome Analysis

1:83-119; Smith, D. R. et al., 1990, Amplification of large artificial chromosomes,

Proc. Natl. Acad. Sci. U.S.A.

87:8242-8246).

The vector may also comprise restriction enzyme sites. Digestion by the appropriate restriction enzyme allows for liberation of virus from YAC vector DNA by restriction enzyme cleavage. It is preferred that the restriction enzyme sites are absent from the CMV genome. CMV DNA replication can be initiated by circularization of the linear virion DNA by ligation of complementary 3′ base overhangs following infection (Tamashiro, J. C. and Spector, D. H. 1986, Terminal Structure and Heterogeneity in Human Cytomegalovirus Strain AD 169.

J. Virol.

59:591-604; Spaete, R. R. and Mocarski, E. S. 1985, The a Sequence of the Cytomegalovirus Genome Functions as a Cleavage/Packaging Signal for Herpes Simplex Virus Defective Genomes.

J. Virol.

54:817-824; Kemble, G. W. and Mocarski, E. S. 1989, A Host Cell Protein Binds to a Highly Conserved Sequence Element (pac-2) within the Cytomegalovirus a Sequence.

J. Virol.

63:4715-4728; McVoy, M. A. and Adler, S. P. 1994, Human Cytomegalovirus DNA Replicates after Early Circularization by Concatamer Formation, and Inversion Occurs within the Concatemer.

J. Virol.

68:1040-1051). In a preferred embodiment, the pRML vectors comprise a Pac I site at one end of the YAC-encoded virus (FIG.

2

).

The targeting segments for cloning CMV virion DNA may be derived either from natural restriction products or PCR products. The CMV DNA can comprise at least a portion of a CMV genome. Preferably, the CMV comprises about at least 50, 100, 500, 1,000, 5,000, 10,000, 100,000, 150,000, or 200,000 base pairs of CMV DNA. Preferably, the CMV DNA comprises an entire CMV genome. It has been shown that infectious virion DNA contains a variable number (at least two) of a sequence copies at the long-arm terminus and a single or no a sequence at the short-arm terminus (Tamashiro, J. C. and Spector, D. H. 1986,

J. Virol.

59:591-604; Spaete, R. R. and Mocarski, E. S. 1985,

J. Virol.

54:817-824; Kemble, G. W. and Mocarski, E. S. 1989,

J. Virol.

63:4715-4728; McVoy, M. A. and Adler, S. P. 1994,

J. Virol.

68:1040-1051). In the instant invention, the targeting vectors for the long-arm terminus preferably comprise an a-a fragment while the short arm terminus fragment preferably contains a single a sequence immediately flanked by a restriction enzyme site, preferably that of PacI.

An a sequence for use in the instant invention may be obtained by cloning the genomic termini of CMV such as that of the Towne CMV strain. It is possible to utilize a sequences obtained from other CMV strains, although the Towne strain is a preferred source. CMV DNA may be isolated from purified virions and blunt ended using T4 DNA polymerase. The DNA may then be cut with XmaI restriction endonuclease and ligated to the pBS-Sk (Stratagene) vector digested by XmaI and HincII. The resultant library of ligated fragments are then subjected to PCR using a nested set of primers. The products of the final PCR step are directly cloned into a vector such as pGEM-T (Promega).

To construct CMV YACs, target DNA is isolated from purified virions. The linearized targeting YAC vector clones may then be introduced, along with CMV virion DNA, into yeast spheroplasts. After transformation, transformants are selected, colony purified, and examined to identify YAC-containing cells. Transformants may be analyzed by, for example, polymerase chain reaction (PCR) using a battery of Sequence-Tagged Sites (STSs). An STS is typically defined by those skilled in the art as a short tract of DNA that can be specifically detected by a corresponding PCR assay and are used as the landmarks on which to base the physical maps of the YAC clones (Nemani, M. et al., 1994, A YAC Contig in 6p23 Based on Sequence Tagged Sites.

Genomics

22:388-396). STS screening has been found to be a rapid method for identifying candidate YAC clones because direct colony PCR assays can be performed. Clones demonstrating the correct STS-content are then examined by pulsed-field gel electrophoresis and Southern blot hybridization to confirm the presence of a YAC of the expected size carrying CMV virion DNA.

Full length YAC-CMV clones are transferred to a permissive mammalian cell line or fresh tissue sample following isolation and fractionation of yeast chromosomal DNA by, for example, pulsed-field electrophoresis. A preferred permissive cell is a human foreskin fibroblast. Other preferred permissive cell lines include human glioblastoma, U373 MG (available from American Type Culture Collection (ATCC), 10801 University Boulevard, Manassas, Va. 20110-2209 as ATCC No. HTB-17); human embryonic lung fibroblast, HEL 299 (available as ATCC No. CCL-137), and human glioblastoma, U-138 MG (available as ATCC No. HTB-16).

CMV-YAC DNA can be isolated and fractioned by extracting the DNA from agarose gels using GELase-based procedures to avoid shearing of the DNA. CMV virions can be embedded in agarose plugs and the viral membranes and proteins removed. The plugs containing virion DNA can be inserted into loading wells for separation by PFGE. Following PFGE, virion DNA bands can be located by size and extracted by, for example, GELase digestion (Epicenter, Inc). A second separation by PFGE can be done to detect any DNA degradation. Following extraction of HCMV-YAC DNA, the DNA can be introduced into the permissive cells by any of several well-known techniques for transfecting cells, including but not limited to calcium phosphate precipitation, direct micro-injection, liposome-mediated transfection, or spheroplast fusion, for example. Such methodologies are described in

YAC Protocols

(1996),

Methods in Molecular Biology

, (The Humana Press Inc., Clifton, N.J.).

The vectors .described herein are also useful for studying the function of essential cis acting genes or nucleic acid sequences. For example, the vectors may be utilized to study the regulation of genes essential to viral replication, the function of the origin of replication, to generate multiple mutations in a single large DNA molecule, or generate cell-based reporter systems for monitoring the infectious program of a virus.

A major advantage of the vectors described herein is the ease and rapidity with which single or multiple mutations may be introduced into a CMV DNA sequence. The capacity of the vectors described herein to generate multiple mutations exceed the capacity of other vectors such as the bacterial artificial chromosome (BAC).

Compositions Comprising YAC-CMV Polynucleotides

The invention also provides compositions comprising YAC-CMV polynucleotides. Compositions of the invention preferably comprise a pharmaceutically acceptable carrier. The carrier should not itself induce the production of antibodies harmful to the host. Pharmaceutically acceptable carriers are well known to those in the art. Such carriers include, but are not limited to, large, slowly metabolized, macromolecules, such as proteins, polysaccharides such as latex functionalized sepharose, agarose, cellulose, cellulose beads and the like, polylactic acids, polyglycolic acids, polymeric amino acids such as polyglutamic acid, polylysine, and the like, animo acid copolymers, peptoids, lipitoids, and inactive virus particles.

Pharmaceutically acceptable salts can also be used in compositions of the invention, for example, mineral salts such as hydrochlorides, hydrobromides, phosphates, or sulfates, as well as salts of organic acids such as acetates, proprionates, malonates, or benzoates. Especially useful protein substrates are serum albumins, keyhole limpet hemocyanin, immunoglobulin molecules, thyroglobulin, ovalbumin, tetanus toxoid, and other proteins well known to those of skill in the art. Compositions of the invention can also contain liquids or excipients, such as water, saline, glycerol, dextrose, malodextrin, ethanol, or the like, singly or in combination, as well as substances such as wetting agents, emulsifying agents, or pH buffering agents. Liposomes can also be used as a carrier for a composition of the invention.

If desired, co-stimulatory molecules, which improve immunogen presentation to lymphocytes, such as B7-1 or B7-2, or cytokines such as MIP1, GM-CSF, IL-2, and IL-12, can be included in a composition of the invention. Optionally, adjuvants can also be included in a composition. Adjuvants which can be used include, but are not limited to MF59-0, aluminum hydroxide, N-acetyl-muramyl-L-threonyl-D-isoglutamine (thr-MDP), N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine (CGP 11637), referred to as nor-MDP), N-acetylmuramyl-L-alanyl-D-isoglutaminyl-L-alanine-2-(1′-2′-dipalmitoyl-sn-glycero-3-hydroxyphosphoryloxy)-ethylamine (CGP 19835A, referred to as MTP-PE), and RIBI, which contains three components extracted from bacteria, monophosphoryl lipid A, trehalose dimycolate and cell wall skeleton (MPL+TDM+CWS) in a 2% squalene/Tween 80 emulsionOptionally, the efficiency of delivery of E1E2 or E2 polynucleotides may be improved by injection of cardiotoxin, purified from the venom of

Naja nigricollis

, about one week prior to an E1E2 or E2 polynucleotide injection. A muscle is injected with from about 0.1 to 20 M of cardiotoxin dissolved in a pharmacologically acceptable vehicle, such as 0.9% NaCl.

Methods of Eliciting an Immune Response

This invention also relates to methods of eliciting an immune response and/or protective immunity in a vertebrate by introducing into the vertebrate a DNA vaccine which comprises a YAC comprising DNA encoding an antigen or antigens, e.g., capsid proteins or polypeptides, of CMV. The uptake of the DNA vaccine by a host vertebrate results in the expression of structural and non-structural proteins, thereby eliciting humoral or cell-mediated inmmune responses, or both, which can provide protection against infection and/or prevent clinically significant cytomegalovirus-caused disease. A CMV deletion mutant may also be synthesized and incorporated into the CMV-YAC construct as a vaccine. One may also utilize a CMV-YAC vector carrying an attenuated or non-replicative CMV genome for direct injection into animal tissue as a vaccine.

YAC-CMV constructs of the invention can be used to elicit an immune response in a vertebrate. Elicitation of an immune response can be used, inter alia, to provide model systems to optimize immune responses to CMV and to provide prophylactic or therapeutic-treatment against CMV infection. YAC-CMV constructs can be used to produce CMV-specific polyclonal and monoclonal antibodies. HCV-specific polyclonal and monoclonal antibodies specifically bind to CMV antigens or epitopes. Preferably, HCMV epitopes are found within the envelope glycoprotein B (gB), for example, the AD-1 epitope (codons 552-635), or the amino terminal 513 amino acids of gB. Preferably, HCMV epitopes are found in the Immediate Early protein (IE), such as the 1E1 epitope. Additional HCMV epitopes are described in Lindenmaier et al.,

Arch. Virol.

113:1-16 (1990). CMV-specific T cells activated by CMV proteins preferably recognize an epitope of a CMV polypeptide. CMV-specific T cells can be CD8

+

or CD4

+

.

Detection and/or quantification of an immune response, such as antibody titer, after delivery of construct of the invention can be used to identify CMV epitopes that are particularly effective at eliciting a CMV immune response. Antibodies elicited by a particular CMV epitope can then be tested using, for example, an ELISA assay to determine which polypeptides contain epitopes that are most effective at generating a strong response. CMV polypeptides or fusion proteins which contain these epitopes or polynucleotides encoding the epitopes can then be constructed and used to elicit a strong CMV immune response.

A YAC-CMV construct of the invention can be administered to a vertebrate, such as a fish, bird, mouse, rabbit, guinea pig, piglet, macaque, baboon, chimpanzee, or human, to elicit an immune response in vivo. Injection of a YAC-CMV construct is preferred. Injection of a construct results in the synthesis of a CMV polypeptide or polypeptides in the host. Thus, the CMV polypeptide is presented to the host immune system with native post-translational modifications, structure, and conformation. A YAC-CMV construct is preferably delivered as “naked DNA.” Administration of a YAC-CMV construct can be by any means known in the art, including intramuscular, intradermal, intraperitoneal, or subcutaneous injection, including injection using a biological ballistic gun (“gene gun”). Administration may also be intranasal or oral. Preferably, a YAC-CMV construct is accompanied by a protein carrier for oral administration. A combination of administration methods may also be used to elicit a CMV immune response.

Administration of a YAC-CMV construct can elicit an anti-CMV immune response in the vertebrate that lasts for at least 1 week, 2 weeks, 1 month, 2 months, 3 months, 4 months, 6 months, 1 year, or longer. Optionally, an anti-CMV immune response can be prolonged by providing one or more booster injections of the construct at 1 month, 2 months, 3 months, 4 months, 5 months, 6 months, 1 year, or more after the primary injection.

A composition of the invention comprising a YAC-CMV construct is administered in a manner compatible with the particular composition used and in an amount which is effective to elicit an anti-CMV immune response, as detected by, for example, an ELISA. A YAC-CMV construct is preferably injected intramuscularly to a large mammal, such as a baboon, chimpanzee, or human, at a dose of 1 ng/kg, 10 ng/kg, 100 ng/kg, 1000 ng/kg, 0.001 mg/kg, 0.1 mg/kg, or 0.5 mg/kg. A YAC-CMV construct can be administered either to a vertebrate that is not infected with an CMV or can be administered to an CMV-infected vertebrate. The particular dosages of YAC-CMV constructs in a composition will depend on many factors including, but not limited to the species, age, and general condition of the vertebrate to which the composition is administered, and the mode of administration of the composition. An effective amount of the composition of the invention can be readily determined using only routine experimentation. In vitro and in vivo models can be employed to identify appropriate doses. If desired, co-stimulatory molecules or adjuvants can also be provided before, after, or together with the YAC-CMV compositions.

Immune responses of the vertebrate generated by the delivery of a composition of the invention, can be enhanced by varying the dosage, route of administration, or boosting regimens. Compositions of the invention may be given in a single dose schedule, or preferably in a multiple dose schedule in which a primary course of vaccination includes 1-10 separate doses, followed by other doses given at subsequent time intervals required to maintain and/or reinforce an immune response, for example, at 1-3 months for a second dose, and optionally at 3-6 months for a third dose, and if needed, a subsequent dose or doses after several months.

In accordance with another aspect of the present invention there are provided isolated recombinant DNA molecules contained in ATCC Deposit No. PTA-2186 and ATCC Deposit No. PTA-2187 deposited with the American Type Culture Collection, 10801 University Boulevard, Manassas, Va. 20110-2209, USA, on Jul. 3, 2000. The deposited materials are yeast cell strains that contain, respectively, the y5-26 and y2-4 recombinant DNA molecules. The deposits have been made under the terms of the Budapest Treaty on the International Deposit of Micro-organisms for purposes of Patent Procedure. The strain will be irrevocably and without restriction or condition released to the public upon the issuance of a patent.

These deposits are provided merely as convenience to those of skill in the art and are not an admission that a deposit is required under 35 U.S.C.§112. The present invention is not to be limited in scope by the constructs deposited, since the deposited embodiment is intended as a single illustration of one aspect of the invention and any constructs that are functionally equivalent are within the scope of this invention. The deposit of material herein does not constitute an admission that the written description herein contained is inadequate to enable the practice of any aspect of the invention, including the best mode thereof, nor is it to be construed as limiting the scope of the claims to the specific illustration that it represents.

The sequence of the polynucleotides contained in the deposited materials, as well as the amino acid sequence of the polypeptides encoded thereby, are controlling in the event of any conflict with any description of sequences herein. A license may be required to make, use or sell the deposited materials, and no such license is hereby granted. References to “polynucleotides,” “clones,” “YAC” and “yeast artificial chromosome” throughout this specification includes the DNA of the deposit referred to above.

Within this application, unless otherwise stated, the techniques utilized may be found in any of several well-known references such as:

Molecular Cloning: A Laboratory Manual

(Sambrook et al., 1989, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.);

Gene Expression Technology

(Methods in Enzymology, Vol. 185, edited by D. Goeddel, 1991, Academic Press, San Diego, Calif.);

PCR Protocols: A Guide to Methods and Applications

(Innis et al., 1990, Academic Press, San Diego, Calif.);

Culture of Animal Cells: A Manual of Basic Technique,

2

nd

Ed.

(R. I. Freshney, 1987, Liss, Inc. New York, N.Y.);

Methods in Molecular Biology

(Vol. 7),

Gene Transfer and Expression Protocols

, (Ed. E. J. Murray, The Humana Press Inc., Clifton, N.J.); Ramsay, M., 1994, Yeast artificial cloning,

Molec. Biotech.

1:181-201; Smith, et al., 1990, Amplification of large artificial chromosomes,

Proc. Natl. Acad. Sci. U.S.A.

87: 8242-8246; and,

YAC Protocols, Methods in Molecular Biology

, (Markie, D., 1996, The Humana Press, Inc., Clifton, N.J.).

The following are provided for exemplification purposes only and are not intended to limit the scope of the invention described in broad terms above. All references cited in this disclosure are incorporated herein by reference.

EXAMPLES

Example 1

Generation of a HCMV-YAC Vector

pRML vectors were engineered (

FIG. 2

) to possess a Pac I site at the end of the YAC-encoded virus to allow liberation of virus from YAC vector DNA by restriction enzyme cleavage. Pac I cleavage sites are not present within the HCMV genome and produce the appropriate overhang for recircularization of the genome after transfection of permissive host cells. The pRML vectors form the backbone of the linearized targeting YAC vector clones.

The targeting segments for cloning CMV virion DNA were derived either from natural restriction products or PCR products. To ensure the production of infectious DNA, the correct structure of the termini was maintained. The targeting vectors for the long-arm terminus were designed to include an a-a fragment while the short arm terminus fragment contains a single a sequence immediately flanked by a PacI site.

The a sequence used in the construction of the targeting vectors was obtained by cloning the genomic termini of HCMV Towne virion DNA. HCMV Towne DNA isolated from purified virions was blunt ended using T4 DNA polymerase, subsequently cut with XmaI restriction endonuclease and ligated to the pBS-SK (Stratagene) vector resected by XmaI and HincII. This library of ligated fragments was then subjected to PCR using a nested set of primers. The outside primer set used the M13 primer and an HH4 primer, 5′-ACGTCGCTTTTATTCGCCGTCG (SEQ ID NO:1) designating a terminal sequence (position 109 to 130). The inside primer set used the T7 primer and HH3 primer 5′-ACACACGCAACTCCAAGTTTCAC (SEQ ID NO:2) (position 51 to 73). The products of the final PCR step were directly cloned into the pGEM-T vector (Promega). An analysis of these clones confirms characterizations of the ends of the HCMV genome (Tamashiro, J. C. and Spector, D. H. 1986. Terminal structure and heterogeneity in human cytomegalovirus strain AD169,

J Virol.

59(3): 591-604).

The target DNA was prepared from purified virions. The linearized targeting YAC vector clones were then introduced, along with HCMV virion DNA, into yeast spheroplasts. After transformation, TRP1 URA3 transformants were selected, colony purified, and examined to identify YAC-containing cells. Transformants were first analyzed by polymerase chain reaction (PCR) using a battery of Sequence-Tagged Sites (STSs). An STS is defined as a short tract of DNA that can be specifically detected by a corresponding PCR assay and are used as the landmarks on which to base the physical maps of the YAC clones (Nemani, M., et al., 1994. A YAC Contig in 6p23 Based on Sequence Tagged Sites.

Genomics

22:388-396). STS screening has been found to be a rapid method for identifying candidate YAC clones as direct colony PCR assays can be performed. The STS markers utilized in generating the vectors of the present invention are illustrated in Table 1. Each STS. produces a specific size fragment containing a diagnostic restriction enzyme cleavage site.

TABLE 1

HCMV STS markers developed for mapping HCMV-YAC vectors

TEST

SIZES

SETS

LOCUS

LEFT PRIMER (SEQ ID NO:)

RIGHT PRIMER (SEQ ID NO:)

SIZE

CUT

(bp)

Set 22

3807-4186

ATCAGGATCGCGACAG (3)

CGTTATCCGTTCCTCG (4)

379

EcoR

I

160, 219

Set 1

11157-11706

ACGAGGTAATCAACGT (5)

ATGTTAAGCCTTAGTC (6)

549

EcoR

I

407, 142

Set 2

16978-17400

GACACCTCTATGTTAC (7)

CGTATATGTACGTCAT (8)

423 (?)

Hind

III

266, 157

Set 3

25799-26218

TAGACAGTATACCCTC (9)

AGTACCACATTTTGC (10)

419

EcoR

I

295, 124

Set 4

36489-36714

ACATGGATTCGTGCAC (11)

ATCGATCTGGAGCACT (12)

225

EcoR

I

184, 41

Set 5

53844-54093

GTGAAGCCGATACGAG (13)

AGGAGACCACGGTTTG (14)

249

EcoR

I

79, 170

Set 6

66701-67183

GGTCCGCAACTTCTGATCCA (15)

CAGATCAGTCCACAGGTTCT (16)

482

Bam

HI

233, 249

Set 7

73910-74261

GCTACCTTGTGCAGTC (17)

GTCCTACGTTGCTACT (18)

351

EcoR

207, 144

Set 8

84721-85094

ACGCAGGTGAATATCC (19)

AGGTTATCGTCAAGCG (20)

373

Hind

III

143, 230

Set 9

107480-107920

CACCATCTTAGGGACGTCTC (21)

GCATGCTCMGACATGCTGA (22)

440

Hind

III

197, 243

Set 10

128975-129337

GATGGTGGMATCGGA (23)

ACCTGTCGGTTGAAGC (24)

362

Hind

III

193, 169

Set 11

136625-136969

TCGTCGACGCATCTGT (25)

ATATCGCACCGATTGC (26)

344

Hind

III

80, 264

Set 12

149371-149770

GTTGGCGTTGAGCACGTCTA (27)

AGCCGACAACCTGCTGCACT (28)

399

Hind

III

274, 125

Set 13

155668-156028

TAAGTGGMGTGGCCG (29)

GACGACGATGACCTCA (30)

360 (?)

Hind

III

195, 155

Set 14

163686-164040

CAGCAATGTTAGCGAG (31)

TCACGCGACTGTCATA (32)

354

EcoR

I

149, 205

Set 15

175465-175737

GTGAAGCGATTGCACA (33)

TCAGGTGCGATTGACG (34)

272

EcoR

I

59, 213

Set 16

185281-185620

CGTTATCCGTTCCTCG (35)

CTTGCGGAATTGACAT (36)

339

EcoR

I

214, 125

Set 17

195675-196056

TATCGTTCGGACGGGA (37)

TTGGATCAGACTCACG (38)

381

Hind

III

162, 219

Set 18

206161-206390

AATCACCGTCATTCCC (39)

CTCCTCAGCTTGTTGT (40)

229

Hind

III

64, 165

Set 19

213192-213496

CTAGCACGATMGGCG (41)

TGACATGTGGCGTACA (42)

304

EcoR

I

244, 60

Set 20

221934-222268

AGTTGGACTACGMGA (43)

CTGTATGTAGAAGACG (44)

334

EcoR

I

123, 211

Set 21

226671-227018

TCCATMCCACCGTGG (45)

GCTGTCGCACTTTCTG (46)

347

Not

I

224, 123

Those clones that were positive for the correct STS-content (listed in Table 2, below) were then examined by pulsed-field gel electrophoresis and Southern blot hybridization to confirm the presence of a YAC of the expected size carrying HCMV virion DNA.

TABLE 2

SUMMARY OF HCMV STS-POSITIVE CLONES

SEQUENCE

(Ref: GenBank No:

X17403)

CLONE

PLASMID 5′

PLASMID 3′

(SEQ ID NO:64)

Y 1-2

pRML1 (H+)

pRML2 (ura) + Ea

119901-178816

Y 3-2

pRML1 (+V)

pRML2 (ura) + Ea

88024-178816

Y 2-4

pRML1 (I2)

pRML2 (ura) + Ea

1-178816(*)

Y 4-7

pRML1 (+d)

pRML2 (ura) + Enx

162053-222057

Y 5-26

pRML1 (I2)

pRML2 (ura) + Enx

1-222057(*)

(*)The insert in plasmid pRML1(I2) goes from nucleotide 228426 (NotI) to the 3′ end of the genome (nucleotide 229075), conjoined to nucleotides 1 through 3967 of the 5′ end of the genome.

Example 2

Infectious HCMV DNA

HCMV DNA was transferred to permissive human foreskin fibroblasts by first isolating and fractionating chromosomal DNA by pulsed-field electrophoresis. In general, HCMV-YAC DNA was extracted from agarose gels using GELase-based procedures to avoid shearing of the DNA. HCMV virions were embedded in agarose plugs, viral membranes and proteins were removed, and then the plugs containing virion DNA were inserted into loading wells for separation by PFGE. Following PFGE, virion DNA bands were located by size (˜240 kb) and extracted by GELase digestion as indicated by the manufacturer (Epicenter, Inc.). Free DNA Irecovered by GELase digestion did not undergo any observable change in band mobility during a second separation by PFGE, indicating that the GELase procedure did not cause any detectable DNA degradation. To avoid shear-induced degradation of the DNA as much as possible, the GELase enzyme was not removed following digestion.

In general, an aliquot of the GELase-purified HCMV DNA was introduced into mammalian cells by either calcium phosphate precipitation methods or by direct micro-injection. Preferably, standard methodologies or modifications thereof for calcium phosphate precipitation methods were used.

In general, transfections were performed by the calcium phosphate precipitation method using standard protocols with a slight modification. Yeast DNA (in 1 ml) was mixed with 100 μl of 2.5 M CaCl

2

in 1 ml of BSE 1×, incubated for 10 minutes at room temperature and added to the cell cultures seeded in 100 mm dishes containing 20 ml of medium.

Preferably, the mammalian cells used were human foreskin fibroblast (HFF) cells. After three weeks of incubation, the HFF cells were harvested and examined for infectious virus. In three independent experiments, infectious particles were recovered at a level of ˜1-10×10

5

FFU/ug of virion DNA. Thus, recovery of infectious virus has been demonstrated for full length HCMV DNA following PFGE.

Example 3

Full-length HCMV-YAC Clones

The full-length recombinant clone Y5-26 was isolated and shown to be replication-competent in HFF cells. Fourteen independent transfers were performed, of which 50% of the cells in four of the cultures developed cytopathic effects (CPE) between days 30 to 40 post-transfer.

Cultures were harvested on day 45 post transfer. All of the CPE positive cultures, but not the CPE negative cultures, tested positive for the presence of viral DNA. One of these cultures showed extremely high levels of viral DNA, comparable to a fully permissive infection with wild-type virus. The high expressor appears to have an intact genome based on an STS analysis, suggesting that Y5-26 DNA is replication competent.

Example 4

The HCMV-YAC Vector as a Tool for Basic Research: Demonstration of Virus over Host Factors in Cross-species Activation of HCMV Early Gene Expression

CMV is a pathogen with a highly restricted spectrum of hosts, and HCMV has a very strong species specificity. HCMV can only replicate in human cells. In other species cells, HCMV can efficiently enter cells, indicating that the species restriction is not at the level of viral binding or penetration. Nowlin et al.,

J. Virol.

65:3114-21(1991). Recent studies have provided direct evidence to show that major IE expression determined by viral immediate-early regulatory sequences is also not species restricted. Angulo et al.

J. Virol.

72:8502-9 (1998); Grzimek et al.

J. Virol.

73:5043-55 (1999).

This Example demonstrates that an essential early gene activation pathway governed by HCMV major IE proteins is conserved between host species. However, a marked divergence in the mechanism for this activation between viral species is observed.

Plasmid based analysis of HCMV UL54 promoter activity in NIH 3T3 cells, using transient expression assays and stable cell lines.

The activation of the HCMV UL54 promoter by HCMV in murine cells using a plasmid based transient expression assay was investigated. For these experiments, a 445 bp DNA fragment containing the UL54 promoter (nucleotide positions 80996 through 81441, numbered with respect to SEQ ID NO:64) was cloned in the plasmid pLHN, to produce pLHN.UL54wt. A 432 bp DNA fragment, corresponding to the UL86 promoter (nucleotide positions 128318 through 128750, numbered with respect to SEQ ID NO:64) was cloned into pLHN, deriving pLHN.UL86.

Briefly, yeast strain YPH857 (Matα ura3-52 lys2-801 ade2-101 his320 0 trp163 leu2 1 cyh2

R

) and derivates were grown in standard media. See Guthrie, C. and G. R. Fink. 1991, Guide to yeast genetics and molecular biology. Methods Enzymol. 194:1-863. Murine NIH 3T3 fibroblasts (ATCC CRL 1658) were propagated in Dulbecco's modified essential medium supplemented with 2 mM glutamine, 100 U penicillin per ml, 100 μg gentamicin per ml, and 10% calf serum. The AD169 and Towne strains of HCMV (ATCC VR-538 and VR-977 respectively) and the Smith strain of MCMV (ATCC VR-1399) were used.

pRML1 and pRML2 were used to create a series of right and left arm plasmids of the YACs, respectively. See Spencer, C. Connelly and P. Hieter. 1993, Targeted recombination-based cloning and manipulation of large DNA segments in yeast.

Methods

5:161-175. pRML1+I

2

, the right arm plasmid, was constructed in three steps: first, an EcoR I fragment from the cosmid pCM1035 (Pari, G. S. and D. G. Anders. 1993, Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication.

J. Virol.

67:6979-88) containing the last 7297 bp of the 3′ end of HCMV, plus the 3967 first bp of the 5′ end, was cloned into pBluescript-SK (Stratagene, US), deriving pBS-SK-I

1

. This plasmid was digested with Not I and self-ligated, creating pBS-SK+I and I

2

. The fragment Not I-Cla I from pBS-SK+I

2

was purified and ligated to pRML1 (Spencer, C. Connelly and P. Hieter. (1993), supra) to construct pRML1+I

2

. This plasmid has 4895 bp of the 5′ end of HCMV. pRML2(ura)+Ea, the left arm plasmid, was constructed by cloning a 3292 bp EcoR I fragment (175524 to 178816) (SEQ ID NO:64) from the cosmid pCM1050 into pRML2 (Pari, G. S. and D. G. Anders. (1993), supra; Spencer, C. Connelly and P. Hieter. (1993), supra). YPH857 has the appropriate auxotrophies to select for both YAC arm plasmids. For the construction of pRML2-Leu2-PUR the Pvu II-BamH I 1.4 kb DNA fragment from pPUR was inserted into the blunt-ended BamH I of pRML2-LEU2 (LEU2 is a yeast protein involved in the synthesis of leucine, which complements the leu2 mutation of YPH857), to produce pRML2/D. Then, the LEU2 yeast gene was cloned in the place of URA3, as a Hind III DNA fragment. In order to develop a mutagenesis shuttle plasmid, in which to clone the different promoters, we generated pLHN. This plasmid has the yeast HIS3 gene as a selectable marker in yeast, the neomycin resistance gene for selection in mammalian cells, and the luciferase gene as a reporter. The promoter sequence and the 3′ end of the targeted gene are both cloned, flanking the unique Sma I restriction site. pLHN.UL54wt was constructed as follows: a 445 bp DNA fragment from the UL54 promoter (nucleotide positions 80996 through 81441 of HCMV genome, Genbank accession number X17403 (SEQ ID NO:64)), present in the plasmid pPolCAT (Stenberg, R. M. et al. 1990, Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains.

J. Virol.

64:1556-65), along with an additional viral DNA fragment from the 3′ region of UL54 (nucleotide positions 77291 through 77516), were cloned into the multicloning site of pLHN, leaving a unique Sma I site in between them. Digestion with Sma I directs the recombination to the UL54 locus.

pLHN.UL54IRM was constructed by cloning the mutated EcoR I-Sma I DNA fragment, into EcoR I-Sma I digested pLHN.UL54wt, replacing the wt fragment with the mutant one. IRM mutagenesis was used for this step. Briefly, the mutagenesis of the inverted repeat IR1 in the UL54 promoter was done as previously described. See Kerry, J. A. et al. 1996, Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection.

J. Virol.

70:373-82. The QuickChange site-directed mutagenesis kit (Stratagene, USA) was used, following the instructions of the manufacturer. Briefly, 50 ng of pLHN.UL54wt DNA was mixed with the oligos IRM-A (GACACGTCGTTACAGATATCGCCTTCCTACGAGG) (SEQ ID NO:47) and IRM-B (CCTCGTAGGAAGGCGATATCTGTAACGACGTGTC) (SEQ ID NO:48), 125 ng each, and then incubated for 1 minute at 95° C., followed by 16 PCR cycles (30 seconds at 95° C., 1 minute 55° C., 15 minutes 68° C.). The reactions were digested with Dpn I, and the digested DNA was transformed into

E. coli

. Several clones were analyzed with EcoRV, a unique restriction site introduced with the IRM mutation. Positive clones of the new pLHN.UL54IRM plasmid were confirmed by sequencing.

PCR was used to test the correct integration of pLHN.UL54wt into the viral sequences of Y24P. Two oligonucleotides were used, YAC54.2 (TCGCCCTGGATATCGACCCGCT) (SEQ ID NO:49), complementary to a region of the UL54 promoter outside of the one included in the plasmid pLHN.UL54wt, and GLprimer2 (CTTTATGTTTTTGGCGTCTTCCA)(SEQ ID NO:50), complementary to the 5′ region of the luciferase gene.

pLHN.UL86 was constructed as follows: a 432 bp DNA fragment, encompassing the UL86 promoter (nucleotide positions 128318 through 128750 of HCMV genome (SEQ ID NO:64), was cloned along with a 522 bp DNA fragment from the 3′ end fragment of the UL86 gene (nucleotide positions 124981 through 125503), with a Sma I site in between them (FIG.

6

A). PCR was used to test the correct integration of pLHN.UL86 into the viral sequences of Y24P. Two oligonucleotides were used, YAC86.2 (GTAGCCGGAGACGGCGGTT) (SEQ ID NO:51), complementary to a region of the UL86 outside of the one included in the plasmid pLHN.UL86, and GLprimer2 (SEQ ID NO:50).

In these recombinants the UL54 and UL86 promoters drive the expression of the luciferase reporter gene. In a first attempt to test if the species restriction for HCMV in murine cells occurs at early times, each plasmid was transiently transfected into NIH 3T3 cells, which were then infected with HCMV, and luciferase activity measured at different times post infection.

Briefly, NIH 3T3 cells were grown in Dulbecco's modified Eagle's medium, supplemented with 10% calf serum. Transfections were done in 6-well plates, unless otherwise noted, using the calcium phosphate precipitation method. See Galang, C. K., C. J. Der, and C. A. Hauser. 1994, Oncogenic Ras can induce transcriptional activation through a variety of promoter elements, including tandem c-Ets-2 binding sites.

Oncogene

9:2913-21. For transient transfections, cells were washed with PBS 16-18 hours after the addition of the precipitate, then incubated 24 hours with 10% calf serum supplemented medium and finally infected with either the Towne strain of HCMV or the Smith strain of MCMV, in 3% calf serum. Stable trans fections were done the same way, except that after the 24 hours recovery in 10% calf serum medium, cells were selected on 400 μg/ml G418 (GIBCO BRL, USA). Clones appeared 10 days after selection. Virus was adsorbed for 2 hours prior to the addition of fresh overlay medium.

To measure the luciferase activity, the Luciferase Assay System (Promega) was used, following the directions recommended by the manufacturer. Cells were washed twice with PBS, and 200 μl Lysis Buffer (provided by the manufacturer) were added to each well. Cells were to scraped and transferred to an Eppendorf tube, frozen and thawed and centrifliged for 2 minutes. The luciferase assays were done in a Micro plate Luminometer LB 96V (EG&G Berthold), using 100 μl extract and injecting 100 μl of Luciferase Substrate, using 2 seconds delay and 20 seconds reading time. The luciferase activity is shown either as the absolute value in relative light units (rlu), as an average of at least two experiments done in triplicate, or as fold activation, in which the absolute value is divided by the corresponding mock-infected sample.

As shown in

FIG. 6A

, the infection caused a general activation of transcription, reflected by a 5-fold activation of the promoter-less pGL3-basic plamid 24 hours post infection when compared to the mock infected sample, followed by a 2.5-fold activation at 48 hours post infection. The overall activation of UL54 promoter was slightly higher (6-fold), but the fold activation was at a similar level as the negative control (FIG.

6

A). UL86 promoter driven luciferase activity responded in a similar manner (FIG.

6

A). Thus, transient expression from isolated HCMV promoters is apparently not specifically. responsive to HCMV infection in murine cells.

To test if the non-responsiveness of the HCMV promoters was due to the nature of the transient assay or to the inherent non-responsiveness of the HCMV promoters in murine cells, we generated neomycin resistant stable clones using the same plasmids. A total of 12 neomycin resistant UL54 promoter clones were isolated, four out of which showed some luciferase activity when infected with HCMV. The results for three representative clones are shown in

FIG. 6B

(2A clones); the luciferase activity values were variable, ranging from 3 to 10-fold peak activation at 24 hours post infection, decreasing by 48 hours. The non-infected samples had some residual activity in the absence of infection, most likely influenced by the site of integration. In order to examine whether the effect of HCMV infection is specific to the expression from UL86 (late promoter), stable cell lines containing the pLHN.UL86 plasmid were investigated. Since HCMV is unable to replicate in murine cells it was expected that the UL86 promoter would not be activated if regulation is specific, while a non-specific enhancement would cause some expression upon infection. In these experiments the UL86 neomycin resistant clones (

6

A clones in

FIG. 6B

) showed no significant activation of transcription either in the absence or presence of HCMV. Overall, we conclude that the UL54 promoter, when isolated from its natural surrounding sequences, is poorly activated by HCMV infection in murine cells.

Cloning and Mutagenesis of a HCMV Yeast Artificial Chromosome

It is possible that the lack of a robust activation of UL54 may be due to integration in host chromatin and/or perhaps the lack of its natural sequence context. To investigate the influence of cis-acting sequences on the activity of the UL54 promoter in the context of its natural genomic location, we constructed a YAC with a 178 kb HCMV DNA fragment, encompassing most of the UL region of the viral genome (FIG.

7

). This part of the HCMV genome lacks the major immediate-early gene region, and is expected to be defective for viral growth. Briefly, the centromeric plasmid, pRML1+I

2

, contains a 4895 bp DNA fragment from the 5′ end of HCMV genome. The non-centromeric plasmid, pRML2(ura)+Ea, has a 3292 bp fragment from the 3′ end of the UL region. Both plasmids were co-transformed into the yeast strain YPH857 with HCMV DNA (strain Towne). Different clones were obtained, and the integrity of the selected YAC (Y24) was verified by several methods. If recombination between the two plasmids and the viral DNA is as expected, a new chromosome of around 178 kb should be generated, encompassing the HCMV genome from the 5′ end to position 178816.

For the separation of yeast chromosomes a Biometra Rotaphor R 23 was used. The yeast DNA samples, agarose gels, and electrophoresis conditions were done following the directions provided by the manufacturer. To separate Y24, an artificial chromosome of approximately 180 kb, a 20 hour run was done at 180 volts, with 15 seconds intervals and a rotation angle of 120°.

FIG. 8A

(left panel) shows a PFGE of Y24, along with the parental strain YPH857. Y24 migrates as an approximately 180 kb extra chromosome in the stained gel. When the separated chromosomes were hybridized to a HCMV UL54 specific probe, only Y24 showed specific hybridization (

FIG. 8A

, second panel).

To further test the overall integrity of the viral DNA, a sequence tagged site (STS) analysis was performed with specific primer sets along the HCMV genome. DNA was prepared from a yeast strain harboring Y24, and PCR was performed using 6 different pairs of STS oligos specific to consecutive regions of HCMV (the locations of the STS are shown in FIG.

7

).

For the STS, analysis specific pairs of primers were designed along the HCMV sequence, with an approximate spacing between them of 20 kilobases, to be able to check for intactness of the viral genome. A subset of those STS pairs was used in this study, as shown in FIG.

6

. PCR was performed using either yeast total DNA of a strain containing Y24 or DNA extracted from HCMV AD169 DNA as positive controls. Each PCR reaction contained 100 ng of template DNA, and 25 pmol of each oligonucleotide of the STS pair in a total volume of 25 μl, using standard PCR conditions. The reactions were incubated-one cycle at 94° C. for 3 minutes, followed by 30 cycles of amplification of 30 seconds at 94° C., 1 minute at 50° C., and 1 minute 72° C. An aliquot of the reaction was loaded in a 1% agarose gel, to check for the presence of the expected DNA fragment size. The pair S22 (oligonucleotides S225, ATGAGGATCGCGACAG (SEQ ID NO:52), and S223, CGTTATCCGTTCCTCG (SEQ ID NO:53), positions 3809 and 4186 in the HCMV genome respectively) amplifies a DNA fragment of 378 bp; the pair S04 (oligonucleotides S045, AGATGGATTCGTGCAC (SEQ ID NO:54), and S043, ATCGATCTGGAGCACT (SEQ ID NO:55), positions 36489 and 36714 respectively) amplifies a DNA fragment of 226 bp; the pair S06 (oligonucleotides S065, GGTCCGCAACTTCTGATCCA (SEQ ID NO:56) and S063, CAGATCAGTCCACAGGTTCT (SEQ ID NO:57), positions 66701 and 67183 respectively) amplifies a fragment of 483 bp; the pair S08 (oligonucleotides S085, ACGCAGGTGAATATCC (SEQ ID NO:58), and S083, AGGTTATCGTCAAGCG (SEQ ID NO:59), positions 84721 and 85094 respectively) amplifies a DNA fragment of 374 bp; the pair S10 (oligonucleotides S105, GATGGTGGAAATCGGA (SEQ ID NO:60), and S103, ATATCGCACCGATTGC (SEQ ID NO:61), positions 128975 and 129337 respectively) amplifies a DNA fragment of 363 bp; the pair S12 (oligonucleotides S125, GTTGGCGTTGAGCACGTCTA (SEQ ID NO:62), and S123, AGCCGACAACCTGCTGCACT, (SEQ ID NO:63) positions 149371 and 149770 respectively) amplifies a DNA fragment of 400 bp.

The results from the experinent are shown in

FIG. 8B

, in which all the specific primer sets amplified DNA fragments of the expected sizes, when compared to the viral DNA. This result demonstrates the overall integrity of the 178816 bp of viral sequence.

The YAC was retrofitted for selection in mammalian cells so that the HCMV YAC could be used for the analysis of essential cis acting sequences in a transgenesis system. The first mutagenesis was targeted to the right arm of the YAC, to introduce the puromycin resistance gene, a mammalian selectable marker. The URA3 gene was substituted by LEU2 plus the puromycin resistance gene, using the plasmid pRML2-Leu2-PUR digested with Not I (see FIG.

7

). This replacement is expected to provide a YAC with the same basic features on the non-centromeric arm, but which now includes the mammalian selectable marker puromycin. Recombinant yeast clones were selected in the corresponding medium (yeast synthetic medium, SD, lacking tryptophan and leucine), and analyzed by PFGE and Southern blot analysis. The expected 180 kb specific band appears in the stained PFGE gel and when the puromycin resistance gene was used as a probe in a Southern blot analysis, only the newly made Y24P YAC gave a specific signal of around 180 kb, indicating that the integration had successfully occurred (

FIG. 8A

, right panel).

To investigate cis-acting sequences and their activity on the UL54 promoter in the context of the UL region, a YAC, Y24P/UL54wt-Luc was constructed, in which a luciferase reporter gene was inserted at position +20 of the UL54 promoter (FIG.

7

). The strategy was as follows: SmaI-digested pLHN.UL54wt DNA, which contains the HIS3 gene for selection in yeast, was retrofitted into a strain containing Y24P. The integration of the plasmid in the YAC sequence would produce histidine prototrophs, in which the correct integration can then be tested by PCR. Using specific primers, directed to the region adjacent to the UL54 promoter but not included in the pLHN.UL54wt plasmid, and to the luciferase gene, a specific DNA fragment of the expected size (1.1 kb) was amplified (

FIG. 8C

, lane 2, compare to Y24P, lane 1). This new YAC has, besides the UL54 promoter fused to luciferase and integrated in its natural position in the HCMV genome, the neomycin resistance gene, which confers an additional marker for positive selection in mammalian cells (see FIG.

7

).

In addition, in order to have a control for HCMV late gene expression, another YAC was construced in which the luciferase gene was inserted downstream of the UL86 promoter. The strategy was very similar to the one used to generate the UL54-luciferase fusion, but in this case the plasmid pLHN.UL86 was retrofitted, digested with SmaI, in a yeast strain harboring Y24P (FIG.

7

). The recombinant clones were selected on medium lacking histidine, and as previously described, the correct integration was confirmed by PCR, using specific primers directed to the region neighboring the UL86 promoter and the luciferase gene (

FIG. 8C

, compare lanes 4 and 5).

Analysis of UL54 promoter activity by stable transfer (transgenesis) of HCMV-YAC to NIH 3T3 cells

Next, the influence of the surrounding UL region on UL54 transcription activity by direct transfer of Y24P/UL54wt-Luc into NIH 3T3 fibroblasts was examined. In these experiments, 10

8

yeast spheroplasts were fused to 2×10

6

mouse fibroblasts. Polyethylene glycol (PEG) spheroplast fusion was performed as described by Julicher et al.

Genomics,

43:95-98 (1997). A yeast strain containing the YAC plasmid of interest was grown until it reached log phase (OD

600

0.6-0.8). The cells were washed twice with water, and resuspended in SCE (1M Sorbitol, 0.1M Sodium Citrate, 60 mM EDTA, pH7.0), 9 mM DTT and 100 U/ml lyticase. When the protoplasts were formed, they were washed twice with SCE. 10

8

yeast spheroplasts were fused to 2×10

6

NIH 3T3 cells in 0.5 ml 50% PEG 1500, 10 mM CaCl

2

for 2 minutes, then washed with serum-free medium and plated. After 48 hours, neomycin was added at a concentration of 400 μg/ml. Colonies appeared two weeks after applying the selection and resistant clones were isolated.

A total of 9 neomycin resistant clones were selected and first tested for luciferase activity after infection with HCMV at a M.O.I. of 10. Six of these clones showed some activity in the luciferase assays; three are shown in

FIG. 9

(clones 31C, 42.8 and 44.11). UV inactivated virus failed to elicit a response (data not shown) and the response of the UL54 promoter to infection in the YAC transgenic lines is proportional to the multiplicity of infection (FIG.

10

). To check the integrity of transferred YACs we performed a STS analysis, using some of the specific pairs of oligos along the HCMV genome. As shown in

FIG. 11

, PCR reactions using DNA extracted from NIH 3T3 did not amplify any DNA fragment of the expected size. However, DNA from both the yeast strain Y24P and from the transgenesis YAC clones showed amplified DNA fragments of the expected size, indicating that intact YACs had been successfully transferred to NIH 3T3 cells (FIG.

11

). In marked contrast to the plasmid transgenic lines, as shown in

FIG. 9A

, the YAC containing NIH 3T3 cells showed very low luciferase activity when mock-infected; 24 hours post infection with HCMV they exhibited a very strong up regulation, which continued to increase up to 48 hours (FIG.

9

A). Furthermore, the absolute values of luciferase activity in the stable YAC clones were less variable and consistently higher than the stable plasmid-containing cell lines. The basal reporter gene levels in mock-infected YAC transgenic cells are subject to a highly specific and very tight regulation.

A comparison between the plasmid and the transgenesis cell lines showed a very strong activation of the-UL54 promoter upon HCMV infection ranging from 170 at 24 hours to 470-fold at 48 hours post infection in the YAC cell lines (FIG.

9

B). This activation is very high compared to the stable plasmid clones, suggesting positive influence of remote viral DNA sequences in addition to more stringent regulation prior to activation. It is noteworthy that the second peak of activation at 48 hrs is not observed with the plasmid transgenic lines.

Transgenesis experiments were also carried out with the Y24P/UL86 to murine cells. The UL86 promoter is a true L promoter (Chambers et al.

J. Virol.

73:5757-66 (1999), which is activated only after the onset of DNA replication. The transfer yielded three neomycin resistant clones, and the presence of the YAC sequences was tested by Southern blot and STS analysis (data not shown). None of these clones showed any luciferase activity before or after infection with HCMV (

FIG. 9A

, clones 5C and 7E). The lack of activation of UL86 transcription in the transgenesis experiments indicates the expected restriction in replication of HCMV in murine cells. Altogether, these results underscore the importance of sequence context in providing optimal level of gene expression.

Analysis of the UL54 promoter activation pathway by HCMV in murine cells

The primary pathway for early activation of the UL54 promoter is dependent on IE86 mediated activation via the IR1 element that binds the cellular transcription factor Sp1. In order to investigate the early activation pathway of HCMV UL54 in murine cells, we accordingly mutated the IR1 element present in the UL54 promoter. Kerry et al.

J. Virol.

70:373-82 (1996).

FIG. 7

shows the point mutations introduced in the IR1 site, which has been previously shown to completely eliminate IE86 transactivation of the UL54 promoter. Kerry et al.

J. Virol.

68:4167-76 (1994).

In agreement with previous studies, the mutant plasmid (pLHN.UL54IRM) showed a much lower activation after transfection in HFF human cells and infection with HCMV (around 17-fold reduction), when compared to the wild type counterpart (data not shown). Kerry et al.

J. Virol.

70:373-82 (1996). On the basis of this result the plasmid pLHN.UL54IRM was retrofitted into Y24P, to study the effect of the IRM mutation in the UL54 promoter, in the context of the UL region.

FIG. 7

shows a schematic of the recombinant generated in yeast (Y24P/UL54IRM-Luc) and its integrity was confirmed by PFGE, STS analysis and Southern blot hybridization (not shown). Transgenesis studies were performed next by spheroplast fulsion of the Y24P/UL54IRM-Luc to NIH 3T3. The PEG fuision produced 8 neomycin resistant clones, three of which showed luciferase activity after infection with HCMV (FIG.

12

). The profile of activation, with a peak at 24 hours, was different to the UL54 wild type promoter (compare FIGS.

9

B and

12

), but most significantly, both the absolute values (not shown) and the extent of the activation (10 to 30-fold, FIG.

12

), were significantly diminished. These results suggest that the pathway used for HCMV early activation of the UL54 promoter is conserved in murine cells, and that the same or functionally similar cellular factors bind to the UL54 promoter. From these experiments we conclude that HCMV E activation of the UL54 promoter by IE transactivators is not restricted by host species encoded cellular factors.

Analysis of the MCMV activation of the HCMV UL54 promoter in YAC transgenic clones

In the experiments described above, a homologous promoter-virus relationship was maintained in a heterologous host cell background, and the pathway of activation of E gene expression uses the same cellular pathway in both human and murine cells was demonstrated. Knowing that the cellular pathway is conserved between human and murine cells, the effect of changing the species origin of the virus was next tested. For these experiments the YAC transgenic clones Y24P/UL54wt-Luc 31C and 44.11 were infected with MCMV, and their levels of activation of the UL54 promoter were examined. In this scenario the cell-virus relationship is homologous (both are murine), while the promoter-virus relationship is heterologous.

Two of the Y24P/UL54wt-Luc stable clones were infected with MCMV, at an M.O.I. of 10, and the luciferase activity at 24 and 48 hours post infection was analyzed. The maximum transcriptional activity was ten-fold lower in the MCMV infection, in comparison with the activation by HCMV (

FIGS. 9B and 13

, clones 31C and 44.11). This lower activation points towards a restriction at a viral trans-acting factor level, making necessary the concordance of species origin of both promoter and viral trans-activators to recapitulate the activation profile of the UL54 promoter. As anticipated, the Y24P/UL86-Luc 5C and 7C clones were not activated by MCMV infection (FIG.

13

). Taken together, these results suggest that there is a dominance of virus over host factors in determining species specificity of E gene expression.

In this Example a YAC transgenesis approach was used to examine the species restriction checkpoint of an essential early gene activation pathway of HCMV in murine cells. Toward this end a YAC vector was designed, encompassing most of the UL region of HCMV. This vector is replication defective, lacks the major IE region, thus permitting the analysis of essential cis-acting sequences within the UL region when complemented in trans. For the purpose of this study we chose to study essential cis-acting sequences of the viral DNA polymerase (UL54) promoter complemented by HCMV infection in murine cells. The isolated UL54 promoter, both in transient and stable transfections, showed a profile of activation not in accordance with an early gene. Only when in the context of the UL region, the UL54 promoter was able to recapitulate the early (48 hr post infection) gene activation described in human cells. Kerry et al.

J. Virol.

70:373-82 (1996). The same plasmids were used for the transfection assays and for the YAC mutagenesis, to avoid variability. In the UL54wt plasmid stable clones, the basal activity in mock-infected cells was not as tightly regulated as in the YAC clones, and the extent and profile of activation was more random. This suggests the need for tight regulation of early events, and perhaps the involvement of long-range cis acting sequences (sequence context) for optimal UL54 gene regulation. Indeed, the results of this study strongly support the suggestion that remote regulatory sequences participate in the control of expression of this essential early gene.

Members of the CMV family have evolved by co-speciation with their host and as a consequence have had sufficient time for acquiring a significant degree of genetic drift. McGeoch et al.,

J. Mol. Biol.

247:443-58 (1995). In particular, the genetics of HCMV speciation has lead to the non-viable replication in other host species. In this case we can assume that genetic changes that have been beneficial or neutral to its natural host background may well be deleterious to another host genetic background because of negative or inappropriate gene interactions that had not been screened by natural selection. For this reason species-specific strains of CMV must have accumulated genetic changes that may be advantageous or neutral with its host species but that produce non-viability in different host species. The results of this study suggest that the virus-host gene interaction pathway for E gene activation is viable between different host species but has significantly diverged between virus species. This strongly argues for co-evolution of viral transacting factors and their viral target promoters. In agreement, the mutation of the IR1 element of the HCMV UL54 promoter showed that the pathway of E activation is equivalent in human and murine cells. Thus, IE86 mediated activation of UL54 via the IR1 element is conserved in murine cells. In support, the primary host factor known to bind the IR1 element is Sp1, in which sequence homology between human and murine Sp1 is over 95%. In contrast, the MCMV transactivator (IE3) not only exhibits more sequence differences (<40% identity) from its related HCMV (IE86) counterpart but also is extremely inefficient at activating the HCMV UL54 promoter via the IR1 element, indicating a divergence of mechanism of action. A prediction from these observations is that it would not be informative to study HCMV IE proteins in the context of MCMV infection. Consistent with this notion, we find that IE3 mutant of MCMV is poorly complemented by HCMV infection in murine cells (AA & PG, unpublished results).

In summary, Example 4 shows the use of a YAC transgenesis system to explore critical host-viral gene interaction pathways in the cross species activation of a key early gene promoter of HCMV, UL54. Example 4 shows a clear dominance of virus factors (major immediate early proteins) for the transactivation of the UL54 early promoter, and point for a species specificity checkpoint at later times of infection.

The present invention is not to be limited in scope by the specific embodiments described herein, which are intended as single illustrations of individual aspects of the invention, and functionally equivalent methods and components are within the scope of the invention. Indeed, various modifications of the invention, in addition to those shown and described herein will become apparent to those skilled in the art from the foregoing description and accompanying drawings. Such modifications are intended to fall within the scope of the appended claims.

All publications and patent applications mentioned in this specification are herein incorporated by reference to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference.

64

1

22

DNA

Human cytomegalovirus

1
acgtcgcttt tattcgccgt cg 22

2

23

DNA

Human cytomegalovirus

2
acacacgcaa ctccaagttt cac 23

3

16

DNA

Human cytomegalovirus

3
atcaggatcg cgacag 16

4

16

DNA

Human cytomegalovirus

4
cgttatccgt tcctcg 16

5

16

DNA

Human cytomegalovirus

5
acgaggtaat caacgt 16

6

16

DNA

Human cytomegalovirus

6
atgttaagcc ttagtc 16

7

16

DNA

Human cytomegalovirus

7
gacacctcta tgttac 16

8

16

DNA

Human cytomegalovirus

8
cgtatatgta cgtcat 16

9

16

DNA

Human cytomegalovirus

9
tagacagtat accctc 16

10

15

DNA

Human cytomegalovirus

10
agtaccacat tttgc 15

11

16

DNA

Human cytomegalovirus

11
acatggattc gtgcac 16

12

16

DNA

Human cytomegalovirus

12
atcgatctgg agcact 16

13

16

DNA

Human cytomegalovirus

13
gtgaagccga tacgag 16

14

16

DNA

Human cytomegalovirus

14
aggagaccac ggtttg 16

15

20

DNA

Human cytomegalovirus

15
ggtccgcaac ttctgatcca 20

16

20

DNA

Human cytomegalovirus

16
cagatcagtc cacaggttct 20

17

16

DNA

Human cytomegalovirus

17
gctaccttgt gcagtc 16

18

16

DNA

Human cytomegalovirus

18
gtcctacgtt gctact 16

19

16

DNA

Human cytomegalovirus

19
acgcaggtga atatcc 16

20

16

DNA

Human cytomegalovirus

20
aggttatcgt caagcg 16

21

20

DNA

Human cytomegalovirus

21
caccatctta gggacgtctc 20

22

20

DNA

Human cytomegalovirus

22
gcatgctcaa gacatgctga 20

23

16

DNA

Human cytomegalovirus

23
gatggtggaa atcgga 16

24

16

DNA

Human cytomegalovirus

24
acctgtcggt tgaagc 16

25

16

DNA

Human cytomegalovirus

25
tcgtcgacgc atctgt 16

26

16

DNA

Human cytomegalovirus

26
atatcgcacc gattgc 16

27

20

DNA

Human cytomegalovirus

27
gttggcgttg agcacgtcta 20

28

20

DNA

Human cytomegalovirus

28
agccgacaac ctgctgcact 20

29

16

DNA

Human cytomegalovirus

29
taagtggaag tggccg 16

30

16

DNA

Human cytomegalovirus

30
gacgacgatg acctca 16

31

16

DNA

Human cytomegalovirus

31
cagcaatgtt agcgag 16

32

16

DNA

Human cytomegalovirus

32
tcacgcgact gtcata 16

33

16

DNA

Human cytomegalovirus

33
gtgaagcgat tgcaca 16

34

16

DNA

Human cytomegalovirus

34
tcaggtgcga ttgacg 16

35

16

DNA

Human cytomegalovirus

35
cgttatccgt tcctcg 16

36

16

DNA

Human cytomegalovirus

36
cttgcggaat tgacat 16

37

16

DNA

Human cytomegalovirus

37
tatcgttcgg acggga 16

38

16

DNA

Human cytomegalovirus

38
ttggatcaga ctcacg 16

39

16

DNA

Human cytomegalovirus

39
aatcaccgtc attccc 16

40

16

DNA

Human cytomegalovirus

40
ctcctcagct tgttgt 16

41

16

DNA

Human cytomegalovirus

41
ctagcacgat aaggcg 16

42

16

DNA

Human cytomegalovirus

42
tgacatgtgg cgtaca 16

43

16

DNA

Human cytomegalovirus

43
agttggacta cgaaga 16

44

16

DNA

Human cytomegalovirus

44
ctgtatgtag aagacg 16

45

16

DNA

Human cytomegalovirus

45
tccataacca ccgtgg 16

46

16

DNA

Human cytomegalovirus

46
gctgtcgcac tttctg 16

47

34

DNA

Human cytomegalovirus

47
gacacgtcgt tacagatatc gccttcctac gagg 34

48

34

DNA

Human cytomegalovirus

48
cctcgtagga aggcgatatc tgtaacgacg tgtc 34

49

22

DNA

Human cytomegalovirus

49
tcgccctgga tatcgacccg ct 22

50

23

DNA

Artificial Sequence;

misc_feature

Description of Artificial Sequence 5′ primer
complementary to the 5′ region of the luciferase gene.

50
ctttatgttt ttggcgtctt cca 23

51

19

DNA

Human cytomegalovirus

51
gtagccggag acggcggtt 19

52

16

DNA

Human cytomegalovirus

52
atgaggatcg cgacag 16

53

16

DNA

Human cytomegalovirus

53
cgttatccgt tcctcg 16

54

16

DNA

Human cytomegalovirus

54
agatggattc gtgcac 16

55

16

DNA

Human cytomegalovirus

55
atcgatctgg agcact 16

56

20

DNA

Human cytomegalovirus

56
ggtccgcaac ttctgatcca 20

57

20

DNA

Human cytomegalovirus

57
cagatcagtc cacaggttct 20

58

16

DNA

Human cytomegalovirus

58
acgcaggtga atatcc 16

59

16

DNA

Human cytomegalovirus

59
aggttatcgt caagcg 16

60

16

DNA

Human cytomegalovirus

60
gatggtggaa atcgga 16

61

16

DNA

Human cytomegalovirus

61
atatcgcacc gattgc 16

62

20

DNA

Human cytomegalovirus

62
gttggcgttg agcacgtcta 20

63

20

DNA

Human cytomegalovirus

63
agccgacaac ctgctgcact 20

64

229354

DNA

Human cytomegalovirus

misc_feature

Human cytomegalovirus strain AD169
(GenBank X17403.1)

64
gggccgcgtg gtgggtcctc gaggggcggg ggggtgtttt tagcgggggg gtgaaacttg 60
gagttgcgtg tgtggacggc gactagttgc gtgtggtgcg gaggacggcg acggcgaata 120
aaagcgacgt gcggcgcgca cggcgaaaag aagacgcgtg tctgtgtctg tgtgattccc 180
cggggaaaag aggaagttcc cgggggacgg cagcatgggt ccctggggac acacgaaaag 240
caacgcccgg gggcgaggga cgacggccct ggggaccgcg ggggaaataa cggccgcgag 300
gccacacact cgttcctgcg aagccgcaca ccccgaggcc gcgcacaccg ccgacacacc 360
ccgccaccac accccgccgg cacacccgcc acacgcccgc gacacacccg gcacgacaca 420
cccggcacac gcccgcgaca caccctgaca caccctgcca acacaccccc gacacaccca 480
acacacgccc gcgacacacc cggcacacac ccacccggcc gcgccccgac acacccaaaa 540
caccgccggt gcggggccgc gtggtgggtc ctcgagggag tgttgagggc cgtaagcgtg 600
ttgtgtccga cgctgcctgc gcactgccgg tgcgtgtcgt cccacggtat ttgttgtcgg 660
caccgggctt cgggacggtg tttcggcgcg ctgccggtgc gttccacggt ccttgcctgt 720
gtcgtttcgg cgctgcgctt gtcgggggtt ttcgagcgtt ctggccgccg gcgatgccgg 780
ggtgttgcgg agacgggggg tgtgcgggac ggtgttgggg ccggggacgg gggttgcgct 840
ggggccgggg ctgttcgcgc cgcgtagggg aggttacgtt ggggacgggg acagtttgcg 900
gcgcggacca gggaacccac ctcacctatt taacctccac ccactacaac acacacatgc 960
cgcacaatca tgccagccac agacacaaac agcacccaca ccacgccgct tcacccagac 1020
gcccaacaca cgttaccctt acaccacagc aacacacaac cgcatgtcca aacctcggac 1080
aaacacgccg acgaagaaca ccgcacacag atggagctcg acgccgcaga ctacgctgct 1140
tgcgcacagg cccgccaaca cctctacgat caaacacaac ccctactact cgcatacccc 1200
aacaccaacc cacaggacag cgctcatttt cccacagaga atcaacatca actcacgcat 1260
ccacttcaca acattggcga gggcgcagca ctcggctacc ccgtcccccg cgcggaaatc 1320
cgccgcggcg gtggcgactg ggccgacagc gcaagcgact ttgacgccga ctgctggtgc 1380
atgtggggac gcttcggaac catgggccgc caacctgtcg tcaccttact gttggcgcgc 1440
caacgcgacg gcctcgctga ctggaacgtc gtacgctgcc gcggcacagg ctttcgcgca 1500
cacgattccg aggacggcgt ctctgtctgg cgtcagcacc tggttttttt actcggaggc 1560
cacggccgcc gtgtacagtt agaacgtcca tccgcgggag aagcccaagc tcgaggcctc 1620
ttgccacgca tccggatcac ccccatctcc acatctccac gtcggaaacc gccgcacccc 1680
gccacatcca ccgcatcgca ccacccacat gcttcgcctc ggtcagatca cacgcttttt 1740
cctgtcccat ctacaccctc agccacggtt cacaatcccc gaaactacgc cgtccaactt 1800
cacgccgaaa cgacccgcac atggcgctgg gcacaacgcg gtgaacgtgg cgcgtggatg 1860
ccggccgaga catttacgtg tccaaaggat aaacgtccct ggtagacggg gtagggggat 1920
ctaccagccc agggatcgcg tctttcgccg ccacgctgct tcaccgatat ccaataaacc 1980
catcccctcg ccacgacgtc tccgcgtatc tttgtagcct caagaatccg tccccacgtc 2040
cacccatccc gagcactcca cacgccataa caaaccacgg acacgacaaa tgcatgcaaa 2100
cttctcattt attgtgtcta ctactctgtg ttgctacagg gagtgaagag ggtgaaggca 2160
aagaaaaaaa aaaggaacaa aataatagat tagcagaagg aataatccgt gcgaccgagc 2220
ttgtgcttct tttcttataa ggaggcaaat atactaggga aaacataaga ataggaagaa 2280
accgaggttt gggagaaaag ctgagataaa atagcgcatt ttccatacag aggttgttgt 2340
ttttgtggat cctaagaggt ttcaagtgcg aatctcaaag ttctcacgag aatattgtct 2400
tcaagtatcg acaactgtgg tccaagattt ttttttggtc tttttaggtt ctgcgaggga 2460
catcacgatg gatcgttgcg atgaagtcac gcgtacgcct ctggtgtggc gcggtgtcgt 2520
gacaggagag tgtgttttca gtgcagagct gtcttgattc ctatatccga gtatctgttt 2580
tctcgtaagg acggtaatct tctttggtgt aagtacatct aaaagctgca aactatattt 2640
taagggctgt ctctaggtgt actttgatgc tggagttttt cgctgtgttg atgtgaataa 2700
atctactact actattatat gcagaaagag tgattatgcc gagacaagat tgcattggct 2760
gaactgtttc aaaaacgcct acactctact tatccgtaaa cctaaggtaa tactatgtgt 2820
aagttgtttt tttttctttt tgtagtaaaa tggtgatacg tgcaattaaa actgtattcc 2880
atgtttccat cctttcattt caactttaaa ggcggctttg agagcgaaga agtgcgagga 2940
taaaaatgga tgactccttc gtgtccaggg agtcgactac tgcaacgctg attgattaaa 3000
agatggtctc cgatgatgat gttgttattg atcgaatcat ggtgcagaac ggcgacggag 3060
aggagcgtgt ccgccgccgg gaaggtggtc tctttctctt ttcttttttc aagaaatctt 3120
ccatgtgttt atcgtagtga tcgaaatcga ctgatctcgg gttctttttg ttggtttctt 3180
ttcggttaat catgtattgt tttctttttt tacagaaaga tacttttttt catgagcaat 3240
tcctcgcccg gcgccggcat gccgaggtgg ggccactgcg atcagcggca tgccgacgcc 3300
gacccgggga tcttggattc accgttttct ctcttctctc tctacataca gaccgggtgg 3360
caggagcggt aaggaatcat cgtcgtcttt cattcttcga tgattatggt aatactaaat 3420
cttatctagg agcatataca tctaagattg gagtactagt agtcgtttgt ggtttctatt 3480
tttttttata tttatctatg acagtttttc tgtttttcgt tttgataata atataataaa 3540
aactcatgga cgtgaaatct ggcttggttg tggtgatttc attctcatta ttgttgtttt 3600
ctttccgtct tgcggatgaa gatgttgcga tgcggttgtt gttggtgttg ctatacaccg 3660
agagagatga tctttttgtt cttctggttc atttcctatg attgtttggc tgctgaccga 3720
cgcgtcagga tgtgcagggc atgcggggaa tcaggaccgg acacgggata atttcatcta 3780
cctatacgga gatcgcggtc ctcgccatga ggatcgcgac aggcgcgtcg agggggcagg 3840
aacacccttg cggattgaca ttcttggtgg tgtttcgttg ttgtcggtag ttgttgttga 3900
cgatgaggat aaataaaaat gaccttgttt ttgttctgtt ttctcttgtt gggaatcgtc 3960
gactttgaat tcttcgagtt atcggaaagc tgaggtaccc aaatgtctgt agcttttttc 4020
tttttaccct cttgtttatc atctgcgatt cgtggtaggt aggagaggga aatgataatc 4080
cgagattaag gaaaggagaa gataaaaaat aaaaaaaaat aataaaacag aagccgaccg 4140
gccgccgacc cgttccccag gaccagccta cgaggaacgg ataacgcggt ggcgacggca 4200
gcggtggtgg cgctgggggt ggcggcagtg gtactgctga tggtagtcgg gacggaggag 4260
aggcgatgca tacatacacg cgtgcatgct gcatgggtgg atggtacggc cgggagacgc 4320
ggaagagaaa ctcacataaa aaggtgacaa aaagagcggt tgaaaaaaga aaacaagatt 4380
cgaccagaca gaagagaagg accggggctt ggcgaccctt ccacgactgc tgttgtcatc 4440
tcggctcctc cgtcttctcc cggccacggg cggctaagtc accgccgttc tccccatccg 4500
tccgagcgcc gaccgaccag ccggccgatt cgcccgccgg ggcttctgga gaacgccggg 4560
gcagcagcga tctggggaag ctgctaaacc cctgcgtttt tatatggtag ctctgccgag 4620
cgcgggctga cgcgttgggt aagcggaaag acgtgtgtga cgaaaagggg tcccatggta 4680
tttcacgtga cgatgaggag atacggtttg gagcacatac ggtttagaaa aagggagttg 4740
tcgtgacaag ggctgaggga cctctgtctc catgtgtgta taaaaagcaa ggcacgttca 4800
taatgtaaaa aagaacacgt tgtaaacaag ctattgctgt atcattcggc tgactatgct 4860
tcattcggac tgattttctt ttcctaacgg cgtaacttaa agtgattaac gtatgatatt 4920
tgttccccag agttatacta tagtcatcat cctaaaattc agatataaat gaacacatgt 4980
cgtatgggat tattaagaaa ccgaaactct ccacagttca ccatcttctt cgtcattcaa 5040
ccgatgaccc actccgtaca acgaatcagt ctgctgcgtc atattgcaaa gcacaagcga 5100
cgtatgcgaa caacttgaaa cacaggctgt tgtattgacg accgttgtac cattattagt 5160
caccaccgtt atcccatgtt tcccacccga tggaaaaccg tcttctatca tcaactgtgg 5220
taagatttcg accctgcgag gtattcagtt tcctcatatc cataacctgg attttatcat 5280
taaaccccaa tattaaacac ttttttagta ccccccaccc accaaaaaat gtgactggac 5340
cggttcctag cagctctggg agccatgttc aggttgaacc acagctacag cgaaaccgag 5400
tccagtgacc ggtaaccacg tccagcccct gcgtatgtac cagtccaagc acgtccggtc 5460
attgttctac acaggaaatc taactaggtc aacgcaattt tattccaccg ttacgcagaa 5520
tactaacaaa aaaacacaca aatttaacga attacacgta gtttattaca tgaaaactgt 5580
aagaacacca attcactaag cgatacaaca tttagctgac ttccaagtgc cacacatcac 5640
cactgtattc atccatgttt tcaccgaacc aacgagacag atcgaagaag ccagaatctc 5700
ccgactttaa attacataaa tccaacgtat tatgaccaca gctcgacaca caaatagttg 5760
cgttactatt cacagtagca ttacctatac ccgtaacgtt gcacaaccac tgatcaccat 5820
tgttaccaaa aacggttttc cacttagttg tcaacggatc tttcctatgc gtaatggtaa 5880
aattactacc agtcgtcgct tttagctcat tacgagtatt atccgcatcc acatatatca 5940
acgtcatagc taggcacgct ataagtaccc cccccccaca atggaatgtt gccaaaccgg 6000
ttctttcccg ttatagccat agcgttccca ggcaaaagca aacgccaaac ctaatgcagt 6060
gaaaagcgct tgcagccaga accagcttat gtaccagcca caatcacatc cggttattgt 6120
ttccacagga aatcctacca ggcaaagccc cgcttgtttt gttcctatct tgtttagcaa 6180
ttcgtaaact gtcagcctag cgacgtccgt ttagatcaaa agtcacgtat atagcgacgc 6240
tgtttccatc cgtttccccg tcccgccgtt tccgaacaac ccacccgggt tcagacaacc 6300
gaccaccaac agaaatatac acacagacca ctgggagttc agttaaagat ttcatcaggt 6360
ttattttggc tgctgctagt cttttgcttc ttagaaaaaa aatacccata tagagaaata 6420
atgatagttt gacaacacat atggcaggga tttcttcttc atcaataaga tatgcaattc 6480
ccccagggag agactttcaa caattgaatt tacaaaaaca aaattacatc aggagaaaga 6540
gaggatacat taataaatat attatatctg gtgtatatac tgaatgctgc tggttcataa 6600
ggtaacgatg ctactttttt taattccaag atggtttttc tttgttagtc ttttgttgac 6660
ttgctggttc ctaaaagttc gcaaaaacga ttgtgtgaag attttatgac gttggttgac 6720
tagttcatga gattctgctg tacgtgtgat ggttattcgc tggttcgttc taagatgagt 6780
atcgtactgt gtctgcgatg gtcgtctctt actggcattc tctcggctgc ctcttgcttt 6840
catgattgaa aaggaaaaaa ggactccgag ggcgcggtca tcttttactt ttcggttttc 6900
tcgttggcgg gtcagaggta gtcagatcat gagactgtcg tggtcgatga aactgtgtct 6960
gctcaagtga cgtccatttc ttgtacggag aaaaaagtca tcgggataaa taaggctata 7020
caaggcgttg tcaagcgtgc ggctctaaac aaattaagcg atacaaaatt acagtaatac 7080
gaataataaa ttacccccct ccccctgtgg tcccccgaga cgagagccac ccatcgtgta 7140
ctctcgcacc acccacgacc acagagggag acgggacgaa gagacgacgc acagcgccat 7200
ctcctcctgg aggccggcga cgttaactgc tacagctgcg gcggcgaaga cagctgcgat 7260
ttgtcggccg acatgccgat ggtatgggcg gcggcggcaa tggccgcggc agcggggagg 7320
agaggagaga gaagaggagc ggggcgtccg aaggcgagga tggcatggtc tcgccggagc 7380
gcccggcttt tatggaacac tcgcgtccgg ttgggtatca cccacaggaa gatgagtcac 7440
aacttccaaa ccatcttgag acccgagtaa cggtttacag gtcgcacgcc agtcagctaa 7500
aaacagcgga cagtcccacg ctgtttctgt tgtggctctc tccagtttcc tcatcaccgt 7560
cccggtctcc gtcgtcatcg gaagaatacc acccgctctc atgcggcagt cgatcggcct 7620
cgacgaacga gacgcggcga cgcctctcca cggccgactg gttgtggtgg tgaaagaaga 7680
gcaccagcaa tcccaggagg agcaacaagc cctcacatgt ccaggaggtc ggggagaggg 7740
cctgtcggag atggccgtga ggcatcacgt acggcagctg aggagaaacg gagaagaaag 7800
gaaaattacc gtcaggggcc ggggttctta ttagagaaac agcacgtagg tcaggatcca 7860
gatgctaatg gcaatcatga tgacgatgat catgcaggcc aagacgcggc gcaccaatgc 7920
cgaatccaat agccgccgtg cctccggttg gtggccggcg gcatctagag acatgatttg 7980
ggggggaccg gcggcgcaaa aagacaggga gatggacagt gtcacggtgt tttgttataa 8040
ttaggacatg gggaccggaa gccgagacag agtactacag ggtgttgaag ggtaacgtga 8100
gggagatcat gtcatgggcg ggctgaagac cgtgcgggga ggattgacgt gtgcggtgct 8160
tgtggaacac ggtgttttaa tatgtatccg cgtgtaatgc acgcggtgtg ctttctggca 8220
ctcagcttgg taagctatgt ggccgtctgc gccgaaacca aagtcgccac caactgtctc 8280
gtgaaatcag aagataccca tttgacgtgc aagtgcagtc cgaataacac atcatctaat 8340
accggcaatg gcagcaagtg ccacgcgatg tgcaaatgcc ggatcacaga acccattacc 8400
atgctaggcg catactcggc ctggggcgcg ggctcgttcg tggctacgct gatagtcctg 8460
ctggtggtct tctttgtaat ttacgcgcgc gaggaggaga aaaacaacac gggcaccgag 8520
gtagatcaat gtctggccta tcggagcctg acacgcaaaa agctggaaca acacgcggct 8580
aaaaagcaga acatctacga acggattcca taccgaccct ccagacagaa agataactcc 8640
ccgttgatcg aaccgacggg cacagacgac gaagaggacg aggacgacaa cgtctgataa 8700
ggaaggcgag aacgtgtttt gcaccatgca gacctacagc acccccctca cgcttgtcat 8760
agtcacgtcg ctgtttttgt tcacaactca gggaagttca tcgaacgccg tcgaaccaac 8820
caaaaaaccc ctaaagctcg ccaactaccg tgccacctgc gaggaccgta cacgcacgct 8880
ggttaccagg cttaacacta gccatcacag cgtagtctgg cagcgttatg atatctacag 8940
cagatacatg cgtcgtatgc cgccactttg tatcattaca gacgcctata aagaaaccac 9000
gcgtcagggc ggtgcggcgt tcgcgtgcac gcgccaaaat ctgacgctgt acaatctcac 9060
ggttaaagat acgggagtct acctcctgca ggatcagtat accggcgatg tcgaggcttt 9120
ctacctcatc atccacccac gtagcttctg ccgagccttg gaaacgcgtc gatgctttta 9180
tccgggacca gggagagttg tggttacgga ttcccaagag gcagaccggg caattatctc 9240
ggatttaaaa cgccagtggt ccggcctctc actccattgc gcctgggttt cgggaatgat 9300
gatctttgtt ggcgcgctgg tcatctgctt cctgcgatcg caacgaatcg gggaacagga 9360
cgctgaacat ctgcggacgg acctagatac ggaacctttg ttgttgacgg tggacgggga 9420
tttacagtaa aagatgcgtg tcgcctgccg aagacctcac catctcacgt acaggcatac 9480
ggcgtataca atcataatat tctatattct gcatagagtt acatgcaaca gtactactac 9540
caatactgca tccatcacat cacccaacac tgcttctacc acctttgtga ccagcgtatt 9600
ttctactccg aataacaaca catcaacgac gccacacaca tctgtcacct cacaagcgtc 9660
aaccattggc aacatcacca acgttacctc cgacttgagt actttcacaa ccgtatattc 9720
tacattcaat acatcatatg ctaatatatc caatacggct gccactacag aattgatttc 9780
aacaaatacc aacactatat tatcttttac caacgtaaca gcaaacgcta catcatctta 9840
taacacaaca atcaccgtaa ctatcacgtc agatgaaact tcgcacaacg tatccactaa 9900
tactgcactt ataagcacgc catggcttac aaattgcagc gccacaacgt acaccacgta 9960
caaccgtact aactcttcca acgcttgtca cacagagaca acaatcatac gtttcaaaga 10020
aactaataca acaggaatag aagggagtaa tgtcaccata aaaggtaatt ctacgtggga 10080
ttgtctttca gtcgcctgga tacgacatta caatcgatcc acacacggac atcatctagg 10140
tcatcgtaag aacgcacata cccaatcttg gtattggtta cgcatcctta cctctcatac 10200
tgtatgtcat tctcaacatg aaagaccttc actgtaccat gacttatgtc gttcgtgcaa 10260
caacacagaa ctacatctgt acgatctaaa tatcaccaat tccggcaggt acagcagacg 10320
ttgttttaaa gaaaattact tcacaggaca tcacgaagat gaaaatttct acctattagt 10380
aacaccaaaa aatcatactg aagctattaa tgctactttc gtttgcccta gatacaacac 10440
cgatatcgaa aatgaagata gagagaaagg aagtcaacat actaacaata cacatcacca 10500
caaacgtaat ctctatcata gctcgcaaag aagccgcacc gtatggacca tcgtgttggt 10560
ttgtatggcc tgcatagttc tgttttttgc acgacgagcc tttaacaaaa agtaccatat 10620
gttgcaagac accgtcagtg aatcagaatt cattgttcga tatcacacag aacatgaaga 10680
ttgagctacg tttccgggca gacatcttat gaagctgaac aataaactaa aacattctgt 10740
aaggctcagc gttcaaagga atattaatgc ccattgagcg agaactaata ttgcaatgga 10800
ctggcgattt acggttatgt ggacgatact aatatccgcg ttatcagaaa gctgcaatca 10860
aacctgttcc tgtcaatgtc cctgtagtac taccgttaac tattccacta gtactgagac 10920
agccacatca acatacagta caacagttat cagcaataaa agcacttcag aatctataaa 10980
ttgctctact gcaactgcac cagcaaccac cgtttctaca aaaccgtcga aaacaaccac 11040
acagatatcc acaacgacaa atacaaacgt tgagactacc acatgtacca acaccaccac 11100
gaccgttact tgtgatggtt tcaattatac agtccataaa agatgcgacc gcagttacga 11160
ggtaatcaac gtaacaggat acgttggtgg caacataact ctaaaaaatg caatcagact 11220
gagaaatggc acaatgtaga ctggattcat tatgagtacc ccacgcataa aatgtgcgaa 11280
ttaggcaact atcaccaaac aacaccacgg cacgacatat gttttgactg caacgacacc 11340
tccctaacta tctacaactt aaccacaaga aacgctggaa aatataccag gcatcaccgt 11400
gataacggtc aagaagaaaa ttactacgta acggtgttaa ttggagacac aacgttatcc 11460
actcttggca catgccctgt aagatataaa gaatctagga acactgaaaa caccattgga 11520
agtaacatca taaaaaccat tgagaaagct aacattcccc tgggaattca tgctgtatgg 11580
gcaggcgtag tggtatcagt ggcgcttata gcgttgtaca tgggtagcca tcgcattccc 11640
aaaaaaccgc attacaccaa acttcccaaa tatgatccag atgaattttg gactaaggct 11700
taacatgcac atcaataaac tttttttaac caataacatg tctctgtttt tttttgttaa 11760
caacctatga tataaagcgg tatattcaat cattactaaa caaaaaaaca tgggcatgca 11820
atgcaacact aaattgttat tgccagtcgc actaataccg gttgtaatca tcctaattgg 11880
tactctagtg cccatacttt tacatgaaca aaaaaaggcg ttttactggc gactttttct 11940
gcaaagtcaa catgtagaag cacccattac agtaacgcag ggagacacag tctacctaga 12000
tgctagcaat aatccctgta attattccag cttttggtac cacggtaatt gcgaactttg 12060
tggatggaac ggatatctac gcaatgttac acattactac acaaacacat cgtgttcccc 12120
gcaattcatg tgcataaacg aaactaaagg tctgcagtta tataatgtaa cattaaacga 12180
ttcaggtgct tatactgaac acgtttacga atgtgatctt tcatgtaaca ttactactta 12240
taacgaatat gaaatactca attacttcga taactgtaac tacaccataa atagcaccaa 12300
gcatattatc accgtggtgt cttcacgtca ttctaaacaa acaaattccc acgtatccac 12360
tcacgctggt tgggcagccg ccgtggtgac ggtaattatg atctacgttt tgatccactt 12420
taacgttccg gcaactctga gacacaaact acgaactaga aacaacgtaa atcgcatagc 12480
gtgattacaa agtatcgaca ctaatttatc caagataaaa tttgattact ccgtgcggtt 12540
ctcaaaaact gtaaggtccc gcttttctac tccatcatga aggatcgcaa tagaatactg 12600
ctatgtatca tctttatttg catcatgtgc ctcatttgta tttactttaa acgtcgttgt 12660
gttcttactc cgtctccaga caaagcggat ctgcgagtgg aatttccctc gttacccccg 12720
tgtatcggca tacaatgtgc tgcatgagaa cacgcgtgac acatagcgta cccctggacg 12780
gtacagttta tgataacgtc attcagggga agtatacatt actatcgacg tgttatcaca 12840
gaacacacag attttctgcg tgttttataa aagagcgtct cgaagcagct tgagccacac 12900
tacggtccag atgacgagcg taatcaaaaa tatgccgcgc agtagtcgaa agccgtactg 12960
agcgtgcgag gcgggtaggg tgccgaacga cggatatgcg tcgttgtcat cttcgactat 13020
aaggatcgcg accgagtctt cggccatggt aaacgtcacc ctgtgtggct ggtatgtagc 13080
gtatccggtt tggaattgtt ctgctccagc tcgggggata gtgaggaatt ctcaagggat 13140
acgggaccca atgactggat aagagaaggg tttttccccg taagatgatc ctcgtatcac 13200
atgaggtctg gatatgtata aatgaagagt gaaataggca cagggaatca gatgccagcc 13260
tcgtgatgca gccgctggtt ctctcggcga agaaattgtc gtctctgttg gcttgcaaat 13320
acatcccacc ttaagcgatg agtccataaa gcaccgttgt ccgggtacgg tgaaagtgac 13380
tcggattgta gcacgtccct tttttttgtt tttgtatcgc ttatcgccac tgacagtgca 13440
atattttgat cgtgaggctg agtatggtta tgatgcttag aacgtggaga ttattaccaa 13500
tggtactact tgccgcgtac tgttattgtg tttttgggac ttgttcaatc ggcacgacga 13560
ctgctcccgt ggaatggaag tctcccgacc gtcagattcc taagaatatt acttgcgcta 13620
actactcagg gaccatcaac ggcaacgtta catttcgagg tcttcagaac aaaacggaag 13680
actttttgca ctggttgtta gggtggggtc ataagtccat ctgttcgttc ttcccgaaac 13740
tccagggcaa ctataacgaa caacattaca gatatgaagt agcgaacctg acgtataact 13800
gcacctataa ccgcttgacg ttgctaaatc tgacgacgga aaacagcgga aagtactatt 13860
ttaaaaggga agatgcgaat ttcacctttt attactcttg ttacaacctg accgtgtcct 13920
aaagaacgca cgtgaagttc cacagagccg cgtggctgta gctattgtgt ttacgttgct 13980
tttgaaatgt taagcgtccc tacggcgcta acatgtttct aggctactct gactgtgtag 14040
atcccggcct tgctgtgtat cgtgtatcta gatcacgctt aaagctcgtg ttgtcttttg 14100
tgtggttggt cggtttgcgt ctccatgatt gtgccgcgtt cgagtcctgc tgttacgaca 14160
tcaccgaggc ggagagtaac aaggctatat caagggacaa agcagcattc acctccagcg 14220
tgagcacccg tacaccgtcc ctggcgatcg cgcctcctcc tgatcgatcg atgctgttgt 14280
cgcgggagga agaactcgtt ccgtggagtc gtctcatcat cactaagcag ttctacggag 14340
gcctgatttt ccacaccacc tgggtcaccg gcttcgtctt actaggactt ttgacgcttt 14400
tcgccagcct gtttcgcgta ccgcaatcca tctgtcgttt ctgcatagac cgtctccggg 14460
acatcgcccg tcctctgaaa taccgctatc aacgtctcgt cgctaccgtg tagctagtta 14520
gccagctgtg tatagtttgt tgtgttttgc ttttgcatat ttgttttcag tcagagagtc 14580
tgaaacgggg tgggagggac ttttacgggt aatgcatgct aagatgaacg ggtgggctgg 14640
ggtgcgcttg gtaactcact gtttgaatac gcgctcacgc acatatgtag cactcaacat 14700
gttagctttt gcccgcacgc cccggggcgt gccgagctgc ctttttaata aagtctgggt 14760
ttccagatac gcgctggttc tgattttgat ggtttgtgcc tctgaaagct ctacgagctg 14820
ggccgtgaca tccaatcgac tgcctaactg tagcacgata actacaacag cgggtcaaga 14880
cgctgaattg cacggtccgg caccgttaag ctgtaatgtg acccagtggg gacgttacga 14940
gaatggaagc acacccgtat tatggtgcac tttatgggga tcacgcacgc gagtctcatt 15000
aggacaccgt gtagcgtttg gctgttcttg gaaaacattt tttatttata acgtttctga 15060
aagtagtggt ggcacttatt atcaaaaagg ttacaactgc accgacaaac atataacact 15120
atcttgtttc aacctaacgg tggttcctcg agcggttcaa agcacaacca ccgtaatgac 15180
acccacggtg gttacaaact ccacattcag tgtgtcactt gttgcgtcga gactgacgac 15240
aaattccagc gcgtttagac acgctagtta tcaacggcaa cagcgtgtcg gaaacgggac 15300
gttatccaag aacataacta acttggcatt cacctacggc agctggggcg tcgcgatgct 15360
gctgttcgcc gccgtgatgg tgctcgttga tttgggtttg cctcaatcgg cttggcgacg 15420
ctggcgaagc cacgtggacg atgaagaacg tggtttgtta atgtaggaaa taaaaggcac 15480
tgtttgagca tgactgtttc caaaccgtaa cgtggtaaat aaatcatggc ttccgacgtg 15540
agctcccatc ttctaacggt tacacaatcc cgttggacaa tacatcatat gtacaataaa 15600
ctgttgattt tggcgttgtt tacccccgtg attctggaat ccatcatcta cgtgtctggg 15660
ccacagggag ggaacgttac cctggtatcc aacttcactt caaacatcag cgcacggtgg 15720
tttcgctggg acggcaacga tagtcatctc atttgctttt acaaacgtgg agagggtctt 15780
tctacgccct atgtgggttt aagcctaagt tgtgcggcta accagatcac tatcttcaac 15840
ctcacgttaa acgactccgg tcgttacgga gcagaaggtt ttacgagaag cggcgaaaat 15900
gaaacgttcc tgtggtataa tttgaccgtg aaaccgaaac ctttggaaac tactacagct 15960
agtaacgtaa caaccatcgt cacgacgaca ccaacggtga tcggcacgaa aagtaacgtt 16020
acggggaacg ccagtttagc accacaacta cgtgccgtcg ctggattctt aaatcagacg 16080
cctcgggaaa acaacacgca cctggccttg gtaggtgtta tcgtatttat agctctaata 16140
gttgtttgta ttatgggatg gtggaagttg ttatgtagta aaccaaagtt atagtgatgt 16200
gctttttatc agggagaagg ttttgtgcca acaatgacta accctgggct atatgcatcg 16260
gaaaattata acggaaatta tgaacttacg gaagccgcca atacagcacg tacaaatagc 16320
agtgactggg taacgttagg aaccagtgcg tcgctgttga gaagcacgga gactgcggtt 16380
aaccctagca acgcgactac ggttactcca caacctgtgg aatacccagc tggggaagta 16440
caatatcaaa gaacgaaaac acattattct tggatgctaa ttattgccat aattctcatc 16500
atttttatta tcatctgtct gcgagcacct caaaaagtct acgatcgctg gaaagacaat 16560
aaacagtacg gacaagtatt tatgacggac acggagctgt gatgaactac aatgtataga 16620
tacacgtggc tgctttggtg gataacaata ttgcttcgta tacaacagtt ctatcaatgg 16680
tggaaaccag atacaacgtc atgcattcag aaaacgggat atgaaggtca aaacctcagt 16740
ctgcctccta gtaatgcatt atcatctaaa gactatactt tttcatggta taaagattca 16800
cttaaagccc ttaacatgtt atgttattat actgaaaaac ttgaagaaat agatagcaag 16860
ccagatacta tacgacgatg ttttttgaat catacattgt ttcttattaa tttaacaagt 16920
cactatagcg ggatttacta cttcgattct ctatacacat atggttgggt attacggaca 16980
cctctatgtt acaatgtcac tgtatattcc atatatcaaa cacacatcca cacaactata 17040
ttgctctatc cgcctacgtc cacatataat tcattaacta tatcatcatt tacctcaacc 17100
aacttaacac ataccgcggt ccactatgcc gccggtaacg ttgaagcaca acacgatact 17160
gccaccccac atacaatgtg gatcataccc ttagttatcg ttacaacaat tatcgtttta 17220
atttgtttca aatttcccca gaaagcttgg aataaattca cacaataccg atacaacagt 17280
atgctcaccg ccgcttaaag aatcaccgtc gagaaaacta aaacgtaaaa agaatggcca 17340
tgtacgttta tttttcagct cactgtttga ataccgtaaa cataatgacg tacatatacg 17400
tgattataca acaggtgttt gtgttatgcg gcgactgatt aaccatatcg tgaaccatga 17460
tcttttccga tggtccgtca tgaccgcaat gatattttac aggtattccg aaacctgtat 17520
ggaggtcact gtcagagtag gtgatccagt taccctcggt agtggacatg gttatcatcc 17580
aggacaaaaa gtacactggt ataaccagtc atgcgtcggc attagcaacg gcgaaaatac 17640
gcatcctatc tgcacctacg accctcctaa acctggtaga cgaaagacaa tgaaaaccac 17700
tccgttacca tcaccactgt tgtacgagtg tcacaattcc acattaagca ttcttcatgt 17760
aaacgtctca gatcccaaaa actattgcag gcgaaaatgt ccaccaaacg gtaactgtga 17820
atttcccaca tgttttacgt tatcactgat ttccagaacg acaaccacca gaaaacccgg 17880
acaaaaaact acgttgtcgc gattaaaaac cacgccaaat aaacatacgc agcacaaaag 17940
atccacgcga agaacgtcac ctagagatta caatgtaacg ggtctgccga aaggctttgc 18000
ggactcgttt accggtaacg tagaggcaca tagagccaaa gatgccgcac acagcgcatg 18060
gatcctcatt gtcatcatca ttatcatagt cgtcatttta tttttcttca agattcctca 18120
aagactcaga gagaaatggg acaccagagg atacctttac aaaggaaccg acggcctgcc 18180
cactacggac tacttatcgt gagcggacgg atatctccgg tttcaaaccc actgtttgaa 18240
tatagggaca gtccctacgg aacctgagaa catgtggaaa tcacctgtgg tagaatgctg 18300
ctcaggtaca ttacctttca tcgtgaaaag gtactttacc tagcgatcgc atgcttcttt 18360
ggtatctaca tcagtttcca cgacgcatgc attctggtac ctgctaaagt aggtactaac 18420
gtcacattga acgcggtaca tgtgcatgac ggtgactatg tgtactggtc ttttggtgga 18480
ggtggagcta atagattaat gtgtcgctat acaccaaggc tagacgaaat tcacaaaaac 18540
accaatcgaa gtttttcatg tcttacaaat cacagtctcc ttctcatcaa tgtaacggaa 18600
gaatatactg attactatcg caccatgacc acattcgtac atcagtccca taattggcac 18660
aaccacggca acaaatggac tttagacaca tgttattatg tatacgttac ccaaaacgga 18720
acacttccca ctaccaccac caaaaaaccc actacgacca cgagaacgac aactaccacc 18780
acaacaaaga aaacaaccac cacgagcacg acaacgacca ccactaccac caagaagacg 18840
acgacaagca ctacccatca tcgacactcc aatcccaaag aatccaccac ccctaaaacc 18900
cacgtagaac ttcacgtcgg tttaggagcc acagcagcgg aaacaccgtt acaaccaagc 18960
ccacagtacc aacacgtggc tacacacgcc ctctgggttt tagcggtcgt aatcgttatt 19020
atcatcatta tcattttcta ctttcgaata ccgcaaaagc tgtggctgct ctggcagcat 19080
gacaagcacg gcatcgtgct catccctcaa accgatctgt gagcaagtcg cgtaggaaat 19140
gattgcatga aatcactgtg aaacgccaac tccgtgccag ctggcgcggc ggacaggcct 19200
ttgacgtatt tgaagccagg cgcgctctcg ataccgaaag gatccgaggg ggctttccaa 19260
agccgacgtc cctgattccc ttcataaagc tgttgaccgg ccctagaaag accaagagca 19320
tgctgtgggc ccactgcggt cgcttcttgc gttatcatct gctcccgctg ctgctgtgta 19380
gactgccatt cttactcctt ttccagcggc cgcagtgggc ccacggcttg gacattgtcg 19440
aggaggacga gtggctacgg gagatacaag gagcgacgta ccagctgtcc atagtgcgcc 19500
aagccatgca gcacgccgga ttccaagtca gagcagcgtc ggtcatgacg cggcgaaacg 19560
ccgttgacct ggaccgaccg ccgctttggt cgggatcgct cccgcatttg cccgtctacg 19620
atgtgcgttc cccgcggccg ttgagaccgc cgtcatcaca gcatcacgcc gtatcacccg 19680
aactgccgtc gcgagacggg atacgttggc agtaccaaga gctgcagtat ctggtggaag 19740
aacaacggcg gcgaaatcag tcgcgcaatg cgattccgag accctcgttc ccccctccgg 19800
atccaccatc gcagccggca gaggatgcac gagacgcgga cgcagaacgt accgaatcac 19860
cacatagtgc agaaagcacc gtcaggcacg acgcgagtga gaacgcagtg cggcgacggc 19920
acgaaagacg gcgctataac gctctgacgg tccgcagccg ggactcgctg ctcctgacgc 19980
gaatacgctt ctccaaccaa cggtgtttcg gacgcgggcg tctgagacat cccgcgggaa 20040
gcggtcccaa caccggcgga ccgcgacccg gcggtgcggg actccgtcaa ctacgccaac 20100
aactgacggt ccgctggcag ctgttccgcc tacggtgcca cggttggaca cagcaggtct 20160
ctagccagat cagaacccgc tgggaggaaa gcaacgtcgt gagccagacg gccacgcgag 20220
tacgtacgtg gttcgtggaa agaaccacgt tttggcgtcg cacgtgggtt ccgagacaga 20280
acccggcggc cgaagcgcaa gaactggccg tcataccgcc ggcacccacg gtgctccggc 20340
agaacgagga accacgtcaa cagcttacgg gagaggagac aagaaattca acgcacactc 20400
aacgtgaaga agtggaggac gtttcgagag agggcgcgag agaagggaat gatgggagcc 20460
gagcaagtgg aaacgacgag agaaggaata atgcgggaag atatgatgat gatcatgagg 20520
ttcaagagcc gcaggtcact tatccagcgg gacaaggaga actgaatagg aggtcacagg 20580
aggagaacga ggaaggtgga ccgtgtgaat cgccgccaat gacgacaaat acgctgaccg 20640
tggcctgtcc gccccgagaa cccccgcatc gtgccctgtt tcgtctatgc ttaggactgt 20700
gggtctcgag ctacctggtt cgacggccca tgacgattta gaatacaccg agccattcct 20760
ttatttcccc ccatccccgg tcgcttatgc gtgttaaaca ctaccaataa agataatctg 20820
ccaatcgcac cttatatata atatgtggtc gcgtgtggtc tttttaagga gctctgaaac 20880
acagacaggt atgggcggtg gtcggctgcc gccgctgtgg ctgccgctac tgatcgcctg 20940
gagcgagtgg ggcaactgct gcctcgatgc gcctccggtg gtgcgttcgc cctgtctgca 21000
gccggtgcgc gaccgcaacc gcgagcggaa cccgggctca ccgcagttgc tgccttacgg 21060
cgaccgtctg gaggtggcct gcatcttccc cgcgcacgac tggccagagg tctctatccg 21120
agtccacctc tgctactggc ccgagatcgt gcgttcgctg gtggtggacg cacgcagcgg 21180
tcaggtgtta cacaacgacg ccagctgtta catcgccggc gggcgctggc gcttcgagga 21240
cggcggcgcg gcgcagcggc tgagcctctc gtttcggctc atcaccgaga ccgcgggcac 21300
ctacacctgc gtgctgggca acgagaccca cagcctggcg accgagacca cggcgctggt 21360
ggccgacgtg cacgacctgc gccactcgga ccgctcctgc gacctggctt tcggatcgcg 21420
ctcacagacg cggtacctgt ggacgcccga tccctccagg ttgcgcagta taaactgcgg 21480
ttgggagggt gaacggcacc gcgtagtcca ctacatcccc ggcacctcgg gtttgctgcc 21540
ctcgtgcgag gaggacgagc gcgaactgtg cgtgcccttc atcagccaga gcattgcgga 21600
caacaactgc agccgccggc atcgagttga cggcgctagg cggcgctatc atctacggag 21660
ggattactgg ctgacggatc cgaagatcgg gttgctggcc gcgggatcgg tggccctgac 21720
ctccctctgc cacctgctgt gctactggtg ttccgaatcg taccggcgtc tgaacaccga 21780
ggaggaaagc gaggcggcgg aggaaactgc cgcgggagaa gcctctgcgg tagcggcggc 21840
ggccgtctct gaggaagagc agcggcggga gtaaacgagg agagccatga agcggatgat 21900
tcgcagtcac ggcaggaaaa cggaatgtca gatgacgagc gccggcgagc gacgcgctcc 21960
gccgtcggtg cgcccatctg cggcagcggt acccgacgcg gcacggcgcc aacgaacgcc 22020
gcgactccga cgtcggtccc atcgcccaca gtagcggtac cagacgcggt tcggcgaatg 22080
aaacgtccgc ctgtacgcgg accgatcacc agaaggcgga cattgggctg tggttcatgt 22140
ttctggtttt tggactgtgt tcgtggttgg cgatgcggta tcgcgcacaa taaattttga 22200
atcgatgtca aggaacgcgt gttttgtatt ttattgggaa tattggcggg gataaacctg 22260
tttcggatgt ttacccttaa tcttaccggg gacctcgttg tcctctcctc cttcttcctc 22320
ggacaccggg ctccatgctg acgtaggtac cgactggggt caaaagcctg ggtacttatg 22380
aggagcgcgc acaaaggacc gttaggcgcc ggcatggagc gtcgccgagg tacggtaccg 22440
ctgggatggg tgttttttgt tctttgctta tctgcctctt cctcgtgtgc tgttgacctg 22500
ggtagcaagt cctccaactc gacctgccgc ttgaatgtga cggagttggc ctcgatccat 22560
cctggggaaa cgtggacgtt acacgggatg tgtatttcta tctgctacta cgagaatgtg 22620
accgaggacg agatcatcgg cgtggctttt acttggcagc ataacgagtc tgtggttgac 22680
ctgtggttgt accagaacga cacggtgatc cgcaatttca gcgacatcac cactaacatc 22740
ttgcaagacg gactgaaaat gcgaaccgtc cctgtgacta aactgtacac cagccgcatg 22800
gtcactaatc ttaccgtggg ccgctatgac tgtttacgct gcgagaacgg tacgacgaaa 22860
ataatcgagc gcctctacgt ccgattgggc tcgctatatc cgagaccgcc cggatccggg 22920
ctcgccaaac acccctccgt aagcgccgac gaggaactgt ccgcgacctt ggcgagagac 22980
atcgtgttgg tctcagccat cactctgttc ttcttcttgt tggccctacg gatcccccag 23040
cgactgtgtc agcggctgcg cattcgcctg ccgcatcgat accagcggtt acgcaccgag 23100
gactgaacgg ataaccgcaa aggccacgtg caacgttcac gctgctataa gaaggccatg 23160
tcccccgtgg acgggtctct ttgacacgag cgcggcacgc cgttgccacg agcatggatc 23220
acgcgctctt cacacacttc gtcggccgac cccgtcactg tcggttggaa atgttgattc 23280
tggacgaaca ggtgtctaag agatcctggg acaccacggt ttaccacagg cgccgcaaac 23340
atctacctcg acgtcgcgct ccgtgcggcc cccagaggcc cgccgagatt cccaaaagaa 23400
gaaaaaaggc ggccgtcctt ctattttggc acgatttgtg ctggctgttt cgacgacttt 23460
tctttcctcg ggaggactca gagccactga tgtcggatcc ggcacggtct cccgaagagg 23520
aggagtaaac aacacacggc taagaggata catcatcaaa gaagatagga ggggtcaaaa 23580
cgcggactga aagtatataa cgccgatcat gtccgaggaa ctgttaataa aacgccatga 23640
tgacaatgtg gtgtctgacg ttgtttgtgc tgtggatgtt gagagtggtg ggaatgcacg 23700
tgttgcgtta cgggtacacg gggattttcg atgatacatc gcatatgacg ttgaccgttg 23760
tggggatttt tgacgggcaa cactttttta cctatcacgt taattccagc gataaagcgt 23820
caagtcgggc caacggtacc atttcttgga tggctaacgt ctcggcggcc taccccacct 23880
acctggacgg ggaaagagcc aaaggtgacc ttatttttaa ccaaaccgag caaaacctgt 23940
tagagctgga aattgcgttg ggttaccggt cacagagcgt gctgacgtgg acgcacgagt 24000
gtaataccac ggaaaacggt agttttgtag ccggttacga gggatttggg tgggacgggg 24060
aaactttaat ggagctcaag gataacctga cactatggac gggccccaat tacgaaatta 24120
gttggttgaa gcaaaacaaa acgtacatcg acggtaaaat taaaaacatc agcgaggggg 24180
atactacaat acaaaggaac tatctcaagg gtaattgcac tcaatggtcc gtcatttata 24240
gcgggtttca accccccgtc acccacccag tggtaaaggg cggtgtccga aaccagaatg 24300
acaacagagc tgaagcattc tgtacatctt acgggttctt tccaggggaa attaatatta 24360
cttttattca ttacggtgat aaggtgcccg aggatagcga gcctcaatgc aatccgctac 24420
ttcccacctt ggatgggact ttccatcagg gatgttacgt agccatcttt tgcaatcaaa 24480
actacacctg ccgcgttaca cacggtaatt ggacggtgga aatccccatc agcgttacct 24540
cacctgacga cagttcctcg ggggaggtcc ctgatcaccc gacagctaac aaacgctata 24600
acaccatgac catcagcagt gtcctcctag ccctgctttt atgcgctttg ctattcgcgt 24660
tcctgcacta ctttaccacc ttgaaacaat acctacgtaa cctggccttt gcgtggcgct 24720
atcgcaaggt ccggtcgtca tgaccagcaa cgccctgtat gagctgtttc gacgtaggtt 24780
accgcgtgcc cccgtcaaca cggtcatgtt tctcacgcga cgcactcgtg atgggttctg 24840
cggtcggttg acgtccatcg ccacgaattc ccactacact atgttcgtgt tagatcacgg 24900
gtccgtgcgc atcgagcgac cgagtcagtc agaagtggat tgcgccagtt taatggaaac 24960
gctgaagcgg attcggttac gaaattcgtg ggtagcgtca gaagacgagc tagatgtgag 25020
tcgcggggac gcgtgacaca aaacgcgttc aggattaacg taggttttcg aaataaccta 25080
cgtccgtgag tgacgcggtt tcgtgttgaa acccgcgccg gttctcacgg tggtttatga 25140
tgaaaccggc gttggggatc tacgcgggtt cctcattcaa cctgcgaaaa gaggaagttg 25200
cggtaaaacc acgtcaataa agacgtcaat gacacctcaa tgttgcgttg gaacggtctt 25260
tatatataca aacgccgtta tgttcagtgt ccggcaagat gctcgggata cgggctatgc 25320
tggtgatgct ggattactac tggatacagt tgataacaaa caatgacact cgaagcaaca 25380
ataccgatac catctttgta tctctcctta ccggggccaa cggagttact cgcacagcca 25440
tcgggggtct gcattcaaac tacaccaact taaccgaggc attcagattc actccagcaa 25500
acacaacaac taactcttcc acggagggta attggagcgt gactaaccta acggagagtt 25560
gcatcaaccg cggtgagtcc tatctaacta ccatctggct tctgaactgc gctgacaaca 25620
atacttattg gtactctgga aatgcctata accatacaat tgacacttgt aaaaatacag 25680
tttcgggata tctcttcttc ggcatgtgcc agctatggaa agattgggtt actaatgctt 25740
ctcacgacac tgtcagaatt cagtcgttgg gaaatgaaat acgctgcatg ctgctcccta 25800
gacagtatac cctcaacgcc acggtggaat ggtacaacaa atctgaaggt gacgtaccag 25860
aagaatttat ggactatgtt atcctgaccc ccttggcagt gcttacatgc ggactgcagg 25920
aagcttatat actcgacaag ggtcgtagat acatgtattt gttttccgtg tcctgcgcgg 25980
gaatcacagg taccgtatct attatactcg tctccctatc gctgctcatc ctcatctgtt 26040
actatcgctg tggccggctt ctgatatgcc cacgcggctt tgaactcttg ccagaattca 26100
ctgaggaaga ggaggaaaaa gaaaaattgt taacgtacaa ggacattgaa gtccaggtgc 26160
ctatccgcac gcggcggctg ctcgtccctt ggatccggga gagcaaaatg tgggtactac 26220
cacccccgct gcctccacga cctccccact taatagaatt cccgccgtct cctccgccgt 26280
cgcctgggcc catgcacatg gtggtctgca tgccagcatg acggactttg aactttgagc 26340
cccaagcggt acggactaca tattttccat aaatctacac tgaacttgag cacaaaaata 26400
ctgacaatgg actgaatata cagactttta tatgatcctt gtacagatgt aaataaaatg 26460
tttttattta aaactggtcc caatgttctt cgggaatcat ggggtgggga cgggggacgc 26520
ggtaaggagc aaaaccgggt acatgggggg gaacatcgtc cagcagtagc accagcggat 26580
tgggtagggg ttgctgcgga ggtcggtcga tgacgatgtc gatctccatc ggcagatccg 26640
gcaacatctc ttcgtctccc tcaccgacca gcactcggcg ctgttctgga tgtatatgat 26700
tttggaaaag cctccgacga gctcgcggcg cgtagaaagc caagcggcgc aagggccggc 26760
gagcccgaaa gtccatgcgc acagatggca tgagtccttg agtgacggtg gtgagctggg 26820
gaacagggct acctcccatc gcgacggtga cagtggatcc atgagagagg cgccgcacgc 26880
tgcatggcta aataccgtga atcccctgac gtcgtctttc gtcccgaacg cgtcatgttg 26940
ggggcgaggc gtaaaccgtc gaggttgaaa aaccgcgtat ctgcgacccg tccggactac 27000
gttgtttttc agaagcggcc acatgacctc gagatgtcgt cacccaaggt atttaacggc 27060
acacagccag acgcgttcgt cagcagcgac gccgacaaga cctcagcatg gctcggaggc 27120
tatggatctt gagcttacta gccgtgacct tgacggtggc tttggcggca ccttctcaga 27180
aatcgaagcg caggtaaacg gaatctgggg aattcaacac aggtaagaaa tacaaaaaat 27240
aacgtgattg tgaacgcggt tatcgtgttt ttgcagcgtg acggtggaac aacccagtac 27300
cagcgctgat ggtagtaata ccacccccag caagaacgta actctcagtc agggggggtc 27360
caccaccgac ggagacgaag attactccgg ggagtatgac gttttgatta cagacggaga 27420
tggcagcgaa catcagcaac cacaaaagac tgatgaacac aaagaaaatc aagccaaaga 27480
aaatgaaaag aagattcagt aacagcagac cccaagggtt aacgattatg ttgactacct 27540
tgttttttat taaaaagctg taaggttttg ctctaaaaac accccgcctc cggtcttttt 27600
tcttttgtat tcggcacgcg aaacacggtt tcttcccata gcctgtctaa ctagccttcc 27660
cgtgagagtt tatgaacatg tatctcacca gaatgctagt ttgtagaggc tatgcgggat 27720
gctgcggcgg cgcgaccttc cctctccacc cagccccgtc aaaacacacg cgactcgagc 27780
ggttcgtatg aaaaataaaa aacagctttt tatttacagg aacggggaaa aaaaaggcac 27840
acggtccgtg ggagacgcgg gttcacgcgt cgtcaaaaag ttggtggtcc actccgtaag 27900
gacaggtagg cttatttagc ttccgcatgc tcctggttcc gtaataaatg ccgttttcgt 27960
ggcagcgtgt catgccgcga gtcacaaact ccatcaaact gtcggccacg atgcaaacgt 28020
gctgattgtt ggcagcaaag acgcgcatac agtcgtccac gaagaggttg atcacgtcgt 28080
aggggctcac caaccagcct aaaggttcca cgtggttact gccgaccatg accctccagt 28140
cgttaatctc gctccagtcg tacagccgaa tcgtggagac gcgaatgacg ctgtaatcac 28200
ccatgaccat gagtcggccg cgatacgtag cacgccactg cgcgaacgcg tggatgtgca 28260
tgcagccggc cagcgctcta agcgaggcgg tgtgcggcag ctcctctggg acggtgatga 28320
agttgcagcg tcgcaaaccg atgttgagaa attcagtgat gctctcggcc acaaaggtca 28380
acgagtcaga gtagatgtgg tcggtccaca ggtacatggc gcccgaggcg cccaggtaca 28440
gttcagacgg cacgttgtga tcgcccttgt gtttaagaaa gttgtaggtg cagatgctgc 28500
cgacgaaacg cagcggctcg gggcagcaga ggtagctggc cagacgctgt gcatcccgtc 28560
cttcgtcgcg caccaagcgc cagcgacgcc ggataacgag gcagcggtct ttgggccaga 28620
ccagggccac gcgttgcccg ggtttccacg gtcgcgacgt cttaggaggc ctccagcggt 28680
cgagcagatt gagaaaacag tccttgatta ccgacatcgc ggtcgcgcgt cggtggacaa 28740
aaagaaatcg ggccgatccg gaaaaaaaaa acgacggcaa aacaccgccg tgctcgagcg 28800
aagggtggcg gagggccaga agaggcggcc ttgacggcgt tggcagcgaa aaaattggca 28860
cgcgagtcaa acgggaagta gcgtcggtgt tttatgcccc aagcagcgtc gtcgtcactc 28920
gtggcgtcac agtcaacggt gctgacgtcc tttggggcag tcgggcacgc gatcgtagat 28980
gccgttgtgg ccgctgaaac gtcggttttc aaacagcagg ttaagtccca gacacatgaa 29040
cgtgttgaga ttatctccca cccggatgta gcggtcgtcg cgcacgtcgc aggcgtagac 29100
ggccccggta taggcgacga cgatggggat aaggtcgacg ggccagcgca agtgaggaaa 29160
gggcgcgttc tcgcccttga ggctgacggt tcccaggccg agaacgcgca ttccgaaagc 29220
ggttttgatg ttgcgcagca agtgaccgcc ttccacgctg ttttcgaaac acctgaggtt 29280
gcatagacgc agttccgttc ccggcgggta cgtcaacggc atgaactgcc cgtggtggcg 29340
gatgatgaat cgcgccatgg tatccaaacc gaggctccag gcgcgcaaca gcgggcgaaa 29400
gtagcgctta accaacgacg aggtcaggta gcgcatgcag tgcagggtct cgacggcgcg 29460
cagcccgacg cgcgcaaact ccatgaggtt gcgggccagg tagtagacgg cggtgtcctc 29520
gcgtacatag caaaaaacat agccctcgtc cgagatgagg cacacagcgg tcttcttctg 29580
ctgatccggc gacaacacgc cctcgttcac gaagcgaccc acgaaggcca ggcgcgtctg 29640
gcaacacagg tagtgactcc aagccttcac gtcctccggt ttgaagtcct cgtccgtctc 29700
gatctcctgc agcactaggt tccagcccgg cggccagacc acgggcaaca cctggcctgc 29760
gttgatgcgc acgtaagctt ccagacagcc caggccgaac tcggccgtga gcgccaggct 29820
agccagatcg ctcatgtgac gcgccgagtc agtgggcgag cccgggggcc cgtcgcacac 29880
cacgctccgt cttcttgtcc tcaccgcggc cagcgtggcg aggacacttt ccgcgcccga 29940
ggctgtatct tcggtttgcc cgccggagcc ggccctcact atataacgtc ccgcccgggt 30000
ctcctccatg tatgcaggta agcaactgag ccgaacgcac ctcagcagac gagaggatgt 30060
cgtcgcggcg tcgcagctcg tcacgtcgct ctggcgaacc ctcgacggtg atttatatcc 30120
cctcgagcaa cgaggacacg ccggcggatg aggaggcgga ggacagcgtt ttcacgagca 30180
cgcgggcgcg cagcgccacg gaagatctgg atcgcatgga ggccggtttg tcgccctaca 30240
gcgtctcctc ggacgctccg tcgtccttcg agctcgtgcg cgagaccggc ggcaccggcg 30300
ccgccaagaa accgagcgaa aagaaacgat cgtcgtcgcg tcggcaaccg cagatcgcag 30360
cgggcgcgcc tcggggctcg ccggcgacac ccaaggccgg caagtcgcct aaagtctcgc 30420
gaccgcctag tgtgccctcg ctgcccgaga acggcgccgg cggcggtggc gacgataaca 30480
gcagcagcgg cggtagcagc agtcgcacca ccagtaacag tagcagaagt accagtcccg 30540
tggcgccagg tgagccgtcc gctgccgagg gcgatgagtt ttccttctgc gacagcgaca 30600
tcgaagactt tgagcgcgaa tgttaccggg tcagcgtggc cgacaatctg ggcttcgagc 30660
ccagcgtggt cgcgccgcag cacgtcgagt atctcaaatt cgtgctgcaa gactttgacg 30720
tgcagcacct ccgccgcctc aacgaatgca tacccatgcc ggccttcgcg ctcaccagcc 30780
tcgtcgaccc cgtcttaaac aacgtagcgc ctggcgagcg cgatctcacg cgtcggataa 30840
tcacgcacgc ggtgatcatc aactattact acgtggcgca aaagaaagcg cgccacatgg 30900
tggaggccat acggaccacc gtgcggggcg acacggtacg ccgggtagcc gcgcaggtca 30960
acaaccagag ccgttcgggg cgtgcggccg cgctagcgct tcattttctc acgtcacgaa 31020
aaggagtgac ggacggccag tacgccacgt ctctgcggcg gctggacgaa gagctgcggc 31080
atcgcggcac gcccgaatcg ccgcggctca ccgaggttta ccagacgcta cgcgattaca 31140
acgtgctctt ctataccgcc cactacacct cgcgcggcgc gctctacctc tatcggcaaa 31200
acctgcagcg gctcaacgag aaccaccggg gcatgctccg gctgctttcg gtcgaagaga 31260
tatgcgaaga gcacacgctc aacgatctgg cgttcctagt aggcgtcgag cttatgatca 31320
cgcactttca acgcaccatt cgcgtgctgc gctgctatct ccagcaccag ctgcagagca 31380
tctcggagct gtgttacctc atctatgtac aactgccgtc gttgcgcgaa gactacgcgc 31440
agcttagtga cgtgatctac tgggccgtca gtcaaaacta cgactacgcg ctctacgcga 31500
gcacgccggc gttgtttgac tttttacgcg tcgtgcgtca gcaggacgcc ttcatttgca 31560
ccgactacgt gtactgcgcc ctgcgtctgc tggcctgtcc cgacagacct attatcggtg 31620
acaccggcgg cagcagtagc tcccaacgcc tcgtaggcga gtttatggtg cgcgatccgc 31680
tgttgcgcga cccgcgcgcc acccacctgc gccagaaact catcacccgc gacatatgcg 31740
tggcgcggtt gcaagcgcag ccctcgagtc gacacattcc ggtcgaacac acgggtgtct 31800
cctccgtcac cctgctcaaa atctttagcc aagtcccccc cgacgaacgc gaagaagaca 31860
cgttacgcga gatggctctt aaagcgttta tggaagcgaa cggtaatcac cccgaacaaa 31920
tctgccgatc cccaccaccc ccgctgccac cgcgcgacta tcctcaacgc gacgagcggg 31980
accgtcaccg tcgcgaccgc cgcgacagcg gggaatactg ttgctgatgg tgggacgaaa 32040
cagcagggcg gaacagttta tgatagaaag tcacaggaaa gtatgtgttg tttttttttt 32100
aatgtaccaa gaataaaaag tgcgtctacg accaaagcgg tgtgtggacg ctcgtcctct 32160
ctgtcttctc cgggtttttt tttcacgtgt tttttccttc ctattttgtt acggcaacag 32220
cgctgatggc acgttgccgg cttcgaacat cgcgtcggtg atttcttgct tgcccggcgt 32280
cacacggtga cgtagcagca cgcggctcac gtagcaggcc gactcgcgga tgacctggcc 32340
gtcggcgtcg cgtcgcaggc ccgagcggtt gccgtgacgc agtctgccct gcgcagcgcg 32400
ctccacgtct tcaaagtagc tgtgtagcag gccgcgctcc agcagctgcg gcagcgagtc 32460
ggcggcgcgc actacaaagt tctcacggct gatctcgtag cacagcacgc tgccgtcggc 32520
cgccacgccg gccacgctgc ggtcccaact gaaaaggttg gcgagtccga tggtgccgat 32580
gacgcgcaac tgaccctggg tcaccaccag cagcttccag tattctacgt cgcgcggggt 32640
gaggatggtc tcctccacgt cgcagacaaa caacgtgtag ccgcgcggat agggcagatc 32700
caggtggcga ccgcgctggc ggcgcataaa atcgtctaaa ttcaaaccgc cgtcgggtgc 32760
gcgcctactc gtcatcgccg cgccttgtcg gtcgatgacc ccacggtgct tataacgcgc 32820
cgccgcggct tcatgtggcg tgacctccga cctcgtgagg ccgaaaacgg cgtacatgaa 32880
gacgctcaaa cttttgaatg tgggcccggt agcgcaccga gggccccggg gcggcgacga 32940
cggcgggccc gagttccagc ggggccttgc ggcggcagcg gttggcgtgg ttgctcagct 33000
cggcgtccga gagcgccgag ctgaactgcg gcagccgcgt gcgatcctgc ggcgcgtccc 33060
cgtgtcgcag cgagtgccag agcaggcgct ggacgcgcgc cgtctcgggc gtcggcggcg 33120
cgcgacagcc ccggcgcagc ttgaaaacgt gcaggcacag cagctcgcgc ttgatgcgca 33180
gcgacacgct gcggtagtcg ggaatccgct gcaccagctc gagaaagtcg cagaaggtct 33240
ccacgaacgt gtcctcggtg aagcgaatgc gcttcagatc gtggacgtgt ttgcgaaacc 33300
gcgacagttc tcgacgttgc acggggttct gagcgagtcc cttgcgcagc agcgcagcct 33360
cgcctttaaa cagcctgatg agccgctgca cgtccccgct caacatacgt atacacgccg 33420
tgtactcgtg acgtatactg gcgcgcagca gccgaatgat acgcagggcc agcacggcgt 33480
tagaggccag gtacatggcg tagccgcgac gcgggttggc acaggcccag cccgcgggga 33540
gcagaaagta gtcgtcgatc agcgtctgcg accagtcggc gaagcccagg tcacgtgata 33600
cgctgtcctg gacgcgggcc acgtcgccgg ccgtgaggtg gcggatcgcc ggcaggtgaa 33660
acgcgcccag gtgtcggttg cgctccagcc tcagctcggc gtgctccaaa cgggaatggt 33720
gggacgccac cgcggagggc gacaaagagg agtggtcatt gccgtcgtgg ttaccgtcgt 33780
ggttaccgcc gttgtcgcgc ccgtcgccgc actcgcaaaa ggccgcgtag aggtccttca 33840
atgccgcttc ggctcgcgcc ataaacgtgg cgtggaaaaa aacggcggcg cggtgcgtcc 33900
ggtacttgac gggcaacccg cggcacaggg ccgccggcag gcagcggccg atgagttcgc 33960
gctcctcggg ctccagaaac aggcacaggg tgccgtccag gcgcaggtac agctcctcgg 34020
tcatcgagca tagctgccgc aagtaatggg tgcgcgtccc aaaggtcttg taatcgagca 34080
acgtgcacac cacgtattgc cccgtggcca cggccagagc gatgcgtttg gcggcacgac 34140
tgatctctgg caagtactgc gcctcgtgca ccagacggcg gaaagcgccg gcgttgagcc 34200
agcgaaaatg ctgcggatcg ggcggcaagg gcacgcctcg aagcgcggcc cagacagcga 34260
ggtccgactc gagcgtcaga ccgcggatgt cgtacttgcc gtgcgccgta gcgcaggctg 34320
aatggaccag acagctgcgg cgaatgtaca ccatggcgtg cttgggatgt ttgggcgccg 34380
gcgttttctt tttctgaccg ccggcggccg ccagatcctc gggcgtgcga cacaacaggc 34440
cggcgcgcac agcctcctgt cgattacgaa tcggcgtcag gtaggcgcgc aggaactggt 34500
gacaaaactc ctcatcatca cgacagtcgt cgagatactc gtacgtggtg agcggatcgc 34560
gaaataggcg ctcgtcaccg tcgtcatggt cttctttagc ctgctcctcc ggctgctggg 34620
ttggcagtgg aggcggcggc tgatccacgg ggttcatgac tgagaggaag aagaaggtgg 34680
cggcgaagcg acgcggagcg acggcggtaa agccagacac cggctatata gctagtcatc 34740
acagtctcct ccttcacgac gcccccgtgc cgctcacgct atccagcacg ctacggcccg 34800
aaaacacgta ctcgctgacg tcgtacgcgg gcgatgtatg gctgctcacc ggtttcgcgg 34860
cgacggttgc gctcgagtcc aacggcgaga agcaaaaacg ccgtgggcaa cgaaaccaga 34920
aggagccctg acggataaaa ccgcgcagcg tctcggccaa cttaaccagc atcgtaccgt 34980
acagcagtac gtgaatgccg ccatgcgcgt ccataaatac ggctttgttc acgggttcca 35040
tccatccgat gactacaaaa tgggcctgtt ctagcacgcc gatcacgaaa ttgttggcct 35100
cgtcggcctc ggccacgttc cacgagccga aagtgaaagt acaagcgggc gagccgccca 35160
ggcggatctt gctaccggcg tggagctgac atacgcgcag cagattggcg cggtcgtgca 35220
gtatctggga gagttcgtac atgcccgcaa aggtgtgctt aaaccacgcg ccctctacga 35280
tctcatccac gtagtcgcgc tcaaagaagc tgtacacggc aaagaggccg ttctcaaaaa 35340
actcgccgaa cgagagcccc agcacgtaca ccttgtcctc gccgggcagg tacgcaaagg 35400
cgtgcccgtg cccggagacc cagatctcgg gcgccgtgtt tgcgtccggc acgcattcgt 35460
acacactgac gaggccgata aagtacaagc ggccagcctg gcgcaggcac gagaagcgcc 35520
ggtaggtctt gtgatcgcgc accaccccaa agtactgagt gtcgcccagc atgatgccgt 35580
gcagcggcgg ccagcacagc gggagccaac gacccgccgt ggcgcgcacg tagcgctgca 35640
ggtgaacccc gctcgcacgc tcgcgcggct tcgggcgctt gtgggtccag gcatcacgca 35700
gaccgcgcca gatgctgctg aacttgggct gcccgcgcag atagagcgac gagagcgagt 35760
caaagtagcc cacgacgagc ctgtcgggag acacaagagc gcgaaaatca aacctagagc 35820
gacgacggtg aaaaaaccga ccagaagcgc gtgtctcaaa cacgctactt tcggttataa 35880
aaacaccgtc gccctatttc tgggcgcgtg tacactgatg actcacctac gctttttgaa 35940
cggcagtctc agctcgggat tggcctcgta cagcgagctg cggtccacgg ggccgatgct 36000
ctcgtagcga aagtcgtcga tgagcagcgc cagccccacg cgcacgaagc ccctgaggtc 36060
gcgcgccagc cgcaccaact tatcctgccc caccagcgcc gcgtacacgg tgcccgtgtc 36120
gccgcagaga atccgcacgc ggtgaaagaa ggtcttgtcc tcggcgccct caatttcgcc 36180
cagcggcatg acgggctcgc gcgtgtacaa cgaacgttga aagcggcgca gcatcgaggc 36240
cgagagcccc agatcgcgcg ccgtgcgcag cactagggaa tgcttctcgg gccagatgag 36300
ggtcagttgc gcctcgcggt gcgcctctac gtaggcgcaa cgagcggcgg tgtcctcgca 36360
ggccagcaac tcgcggaaag ccagcagcga acgtaggtag cggccgcgag cggaggcgcg 36420
cgagcggcgg cacagctcgg cccgatggtc gggatgcacc aagggcacgt taggttgcag 36480
acgcgcgcag atggattcgt gcaccgggtc gcagcggatc atgcccttgg caaaaaatcc 36540
ggccagatcc gaggccaact cgtacaggca gtcctcttgc gcgtcgtagg cgaacacggc 36600
gccgtacgcg tccacgaaca cctggtaccg gcaggtggcg tgcgagaccg tgccaatgag 36660
atgcagagct cggaattcgc cgaaaaagtc gttctggcag tgctccagat cgatctcggt 36720
cagcgagtgc ggcgaatgct cgcccccgac cacgtagatg cactgcgagg gccagcccag 36780
cgacacgcac gagccctcga agcgccgcaa gtaacgccgc aggccctcat agtcgcgtcg 36840
cacgcacagg tcggccaagt cgcgcgtgca aaagacctcg ggtaccaagc agcgtttgcg 36900
acgcggccga cgcgcgtgcc caggcagagg aggaaggcgc gacggcggcg acgacgagga 36960
ggaagacgcc gtggccgccg agcagccctt gcgacggccg gacatgccgg cagtccgcga 37020
cgatccacag gagacaaaaa agcagaagca gcagtagcct cggcgacccg ctccaccccg 37080
tcctccacac gctcagccgc gactgaacgc cggggcgcgc cgctacttgg gtttttatag 37140
ccatctgccc cccgtctcgg gcacccggga gcgatctacg gagacctgac agcagttggg 37200
caacacaaga tagggaaata caaagacact tttaataaaa aacgagacta ctttgtgtgt 37260
gtgctccgta aactgtttat tctccccctc cgcttcgctc tggatgggct ccgggtccgt 37320
caacacgcga ctcgcgcggc aaaaggcacg ctgttgacgg cgcgagagcc cgtcgtgata 37380
gtccatcatg ccccggagat cgtgcacaaa gcagctgtcg ccgcgcagaa accgacgcag 37440
cgtctccacg tgctgcagct gccggcgcgt atcaggagcc gtcatcgctg atgtcgtcat 37500
cgccctgaca ggcgcgtaga tggcttcgcg agatcatgcg cgttttcaac cgccgtgaca 37560
catcaggtcc atcttgagct ggcgccgggc ctcgcgcagg tgttgcacgc gttgtgagcg 37620
ggaggcgagt tcggcttctt gctcgaactc ctgctgctca ctgtccgaga gggtgcgata 37680
aaaggcggca aagtcctcca agtcggctac atgcgccctg ggtctgacgc tccaaagcgt 37740
acgcagtctg atgaagcgga cccatcgagc gtcacggcac gccgtcttga acgcggggcc 37800
cgggaagagg ttcttctccc cggcgcgctc gggccggcga ggccgacgcg gtttatatac 37860
accgtctcgg acggcgggac gccgagcccg cgccgcggcc gctcatccgg agacggcgga 37920
aaccgcgacg ccggaggaaa cggggaccgg caacgacggc ggtggcggcg accagattat 37980
gggggacaaa cccacgcttg tgaccctgtt gaccgtcgcc gtgtcgtcgc cgccaccgtc 38040
gtcgccgctg ccgctcgtca gcttcacgga gctgttgtta ccgccgccgt ccgtcgccgc 38100
cgctgcggtg gcggcgacag cgacgagcga ggtgggcgag aaaaccgcgg agcaagaggt 38160
agcggctgcg gatccggaga ccgggaatga gagaagagaa aacagggaga acgaaggagg 38220
ggagacgagg acgacaggca ccaccgcggt caaaaggtcg cacgacggta tccctcgcca 38280
actggcagag cgcctgcggc tgtgccgcca catggacccc gagcaggact atcgtctgcc 38340
ggcgcaggac gtggtgacct cgtggatcga agcgctacgc gacgcggacc gcgacaacta 38400
cggtcgctgc gtgcgccacg ccaagattca ccgttcggcc tcgcacctga cggcctacga 38460
gtcgtacttg gtgtccatca ccgagcagta caacacggcc tcgaacgtga cggagaaagc 38520
ttcgtacgtg cagggctgca tctttctctc gtttcccgtc atttacaaca acacgcaggg 38580
ctgcggctac aagtacgact ggtccaacgt ggtgacgccc aaggcggcgt acgccgagct 38640
cttctttctg ctctgctcca ccagcgagag ctccgtggtg ctgcaaccgc tcatcaccaa 38700
gggcgggctc tgctcgtcca tggcggttta cgacgaggaa accatgcggc agtcgcaggc 38760
ggtgcagatc ggttttctgc acacacaact ggtcatggtg cccttcgtgc cgcacgcctg 38820
cccgcattac gccgtgcctt tcacgacgcc gggaaagccg ggctgcggcg gtgctccgag 38880
cggcgttgcg gggttggagg aggcggcgcc ctttggacgg gtcagcgtca cgcggcatgg 38940
cgcgacgctg ctatgtcgcg tggaccatct gacctggatc agtaagcgcg taaccacgta 39000
cggacacaaa aaaattacgc gctacctcgc gcagttccgc ggcacgatgg acgacgacga 39060
ggcagcgcta cccggcgagg acgaagcgtg gatcgcgtcc aaaaacgtgc agtacgaatt 39120
catgggtctc attttcaccg tcaacgtgga ttcactatgc gtggacgcgg aacagcgcca 39180
actgctgggc accgtggcca cctccttctg tcaccgcgtc tcggacaaga tcacggcgcg 39240
caacatgccg cgcgcttttt ccttctacct gctgacgagc gcgcagcgcg ggtacgacct 39300
gcgattcagc cgcaacccgt cactcttttt tagcggcgac gcgctcaact gtccgcttct 39360
caatgagccc aacgtgtttt cgctcacggt gcacgcgcct tacgatatcc acttcggggt 39420
gcaaccgcgg cagacggtgg agttggactt gcgctacgtg cagatcacag accggtgttt 39480
cttggtggcc aacttgccac acgaggacgc cttttacacg gggctcagcg tgtggcgcgg 39540
cggcgagccg ctcaaagtca cgctgtggac gcgcacgcgt tccatcgtga tcccgcaggg 39600
cacccccatc gccacgttgt atcaaattac cgagggcgac ggtaacgtgt actcgtacaa 39660
ccaccacacg gtgtttcggc agatgcacgc cgccggaaca accacgttct ttctgggcga 39720
catgcaattg cccgcggaca actttctcac gtctccccat ccctgaccct ccgtccgtcc 39780
tcctttcccg acacgtcact atccgatggt ttcattaaaa agtacgtctg cgtgtgtgtt 39840
tcttaactat tcctccgtgt tcttaatctt ctcgatcttt tggaggatgt tctgcacggc 39900
gtccgacggc gttttggcgc cccccatgcc ggcagaaccc ggttgcggcc ccgtaccgct 39960
cttctggggc gacgataggt cgaaagccac cgttttcatg cccgtcgtgc tcttgacggg 40020
ggaacctacg gcggcggtcc ccgtcgagcg gcgtgattgc aaagccgcgc tcgcccccgg 40080
tttcaggatg gagggggagg ccacaggcgg cgcattcgat acgctgcttt tggccgtaga 40140
cgacggtggg taaacggtgg ttaccgcggg atacgtcggc gtggtcgagg cggcccggct 40200
gctgccggac aggcgacccg gcgcgctacc gctcacgggg accgagggcg gtcgacctac 40260
caccgccttg ccgcccaaag taggtttcaa ggaaggaaca ccgacgcggc tgccccggcc 40320
tttcaccgga gacggggggg cactcttggc cggggacgga gaggctgacg aaagcatgga 40380
cagcggcgat gtggcggggg acacgacatc atcctccgtg ggcgacaaaa cggacgccga 40440
ggctgacggc tgtcgagccg aagaagcgga agaggttccc gcgccagaag tcacgttcct 40500
tgatgacgtc gttttagacg aagccggttg aggttgcaac agcgtggcgg gtaccgtcga 40560
cggcgtgccc gacacctgtt tctctagcct tccctgaacc ggcgtcgacg tcaccgtctg 40620
cgctcgggcg gacgcgtgcg gcgtcgcgac tcgcttgccc agcaccggtt tctggctcgt 40680
ggatgtcgtc gtcattggag acgataactt agctttacgt attctggacg gcgtcgactg 40740
ctcgggcgtc tgactgggag gcgaaatgac gtcgttgttg taatcggacg acggtgttgt 40800
gtgtcccagg ctgacgacgg agccggtgtc cgaggagtcg tcgtcttcct cctcgctgtc 40860
ttcgaccggt gactctgcag tttggtccct taaagcccaa acctcatcag cggcgtcccg 40920
agacgctgtt tgtgtcaccg cggcgcgtgg agtcgacggc ctccgagggg tggtggacac 40980
ggtgttttga gaagccgtgg aagtcgtagg catcctgaag ggattgtaag ccaggtgagg 41040
attcttgagg gcccacgcgc gttcgcgcgg ccagttggcg gggttcatat ccccgggcaa 41100
cggcgccgtc ggagcccagg gcgagttacc gttgaccggg gtttgggtac ccgcgaaggt 41160
aggtgtcggg gccggagcgg gggccgtgga aggattgaca ggcgtcggcg tgaggatggc 41220
agcgccggcg ccagcaggaa cgttaactcc ggcgccgaac gtcaacgtcg gttgctcgaa 41280
cttgtacgcg gtggtgacgg gcggtttggc gctcgtctcg gtatccgtga tgtccaccag 41340
cgtgtcggtg aaacgcggat cttgacggtt ggggggatag ccatccgagc tgtcggaatc 41400
ctcgtcgccc gagaaaagat cccctctggt ctccgtgagc ggcctcacgt cccacgcgct 41460
gtcccgacgg acccttcccg ggctggcctt ggtcacctgc ggggagacga gactgaaagc 41520
cgcgtgacgc tgttgttgtt gcgggatgtt caagggaccg ctggtcggtt tctgactgcc 41580
cgaggataac aggccgctga aaatgctgga aacaccgcca ccactagcgg cgcccttgcc 41640
gctagttccc ggtttcttga tgggcgtaaa gatgtttttc tcgtcatcat catcgtcgtc 41700
gtcctcatcg gcactggagc caaagagcct ccgggaggcg ctcggtttac gtgccggggg 41760
cggtggttgc tgctgacgtt gctgcaggtt ctgctgcctc tcctcccaag ccttcagctg 41820
ctgtttctca cgctgcacca cctcgtcgtc cacccgtttc tgccgctcgc gacgcttttc 41880
ctcttcgtcg taatagccga cggccgccga acgggcagcg tgggcttcgg cggccggtgc 41940
cagagaacca tgggcctcga agcggaacgg tttgtgtccc ttccagggac tggcgatcca 42000
gctccagccg tccagcggct gcgtggggac atgtttcttg ggtaccgacg agaaggccga 42060
accgccgccg agcgagagga gattggcgtc atcgtcaaac tccaacgacg gcgagcgcgc 42120
gcccaaaaac gtgtgcgccg actgtgggaa gctgtccacg tagatatcaa agtcctcgat 42180
gagcagctcc aacagcgtgt cggccgagtc gccgttttcc acggcgtgct tgaggatatt 42240
gcgacagtag ttggaatcaa aggaaaggca catgcgcagc tccttgacca gcagcttgca 42300
gcgctcctga atgcgcgcca gacatttgcg ctccagctcc tcccaagacc tgcgcacgtt 42360
catgatgaga cggcccgtgt acacgagctt gttgacggcg ttgaccagcg ccgtgttggc 42420
gtgccggtcc aggttaaggt cgagcggttt cacgcagaac atgttacggc gcacaccctc 42480
caggttttct tcaatgcgct gcacctccgt atccttgagg tgcacaaagg cgatgggttc 42540
cgtctggccg atggctgtga ccagcgtctc gcgcaccgac atcttggcca gaatgaccgc 42600
gcttacgagc gcgcgttcca cgatctcggc atcgtggcgc acgtccgtat cgaattcggt 42660
acggtctagc acagccaggt ggtcacgcgc cttaccacga tcaccgaacg ggtaagtgta 42720
gccgcgacgc gccacggcca cgcaacgcac ctcgaactcc tcgagcactg aggagaggtc 42780
ggggttgtga aaacgcagct cgcggtagta tcccaaccaa agcatgagct cgttgaacag 42840
caccgtacgc cggtgcaggc gtttttcgcc acattttttc aggatcttgg ggtgtgcctc 42900
gagatccacg tcgggctttt gcgtgagatg gcgcagaaag ttgaccaggg ctaccacatc 42960
gcgccgctgt agaccgataa actgcaaact catgctggct tttctccaga acccggaagc 43020
gtcgtcgccc cggactgcgc ccgcggtctg ctattcgccc acgatggaca ccatcatcca 43080
caactcggtg agcgccccac ctagagggag ggggggtagt ttaatagcgg aggcggatac 43140
gcggttttct tttaagcgcc gctgacttgt ttcttctgtt ttttcgcccc gtgtgctgtt 43200
ccgcccagac ccgcaacaac actcctccgc acatcaatga cacttgcaac atgacagggc 43260
cgctattcgc cattcgaacc accgaagccg tactcaacac attcatcatc ttcgtgggcg 43320
gtccacttaa cgccatagtg ttgatcacgc agctgctcac gaatcgcgtg cttggctatt 43380
cgacgcccac catttacatg accaacctct actctactaa ttttctcacg cttactgtgc 43440
taccctttat cgtactcagc aaccagtggc tgttgccggc cggcgtggcc tcgtgtaaat 43500
ttctatcggt gatctactac tcaagctgca cagtgggctt tgccaccgta gctctgatcg 43560
ccgccgatcg ttatcgcgtc cttcataaac gaacatacgc acgccaatca taccgttcaa 43620
cctatatgat tttgctattg acatggctcg ctggactaat tttttccgtg cccgcagctg 43680
tttacaccac ggtggtgatg catcacgatg ccaacgatac caataatact aatgggcacg 43740
ccacctgtgt actgtacttc gtagctgaag aagtgcacac agtgctgctt tcgtggaaag 43800
tgctgctgac gatggtatgg ggtgccgcac ccgtgataat gatgacgtgg ttctacgcat 43860
tcttctactc aaccgtacag cgcacgtcac agaaacaaag gagtcgtacc ttaacctttg 43920
ttagcgtgct actcatctcc ttcgtggcgc tacaaactcc ctacgtctct ctcatgatct 43980
tcaacagtta tgccacaacc gcctggccca tgcagtgtga acacctcaca ctgcgacgca 44040
ccattggcac gctggcgcgt gtggtgcccc acctacactg cctcattaat cccatcctgt 44100
acgcgctgct gggtcatgat tttctgcaac gcatgcggca gtgtttccgc ggtcagttgc 44160
tggaccgccg cgctttcctg agatcgcagc agaatcagcg agctacagcg gagacaaatc 44220
tagcggctgg caacaattca caatcagtgg ctacgtcatt agacaccaat agcaaaaact 44280
acaatcagca cgccaaacgc agcgtgtctt tcaattttcc cagcggtacg tggaaaggcg 44340
gccagaaaac cgcgtccaac gacacatcca caaaaatccc ccatcgactc tcacaatcgc 44400
atcataacct cagcggggta tgagctttcc tgttacttta ttcagaaagc accagaaccc 44460
gtcgccattt cccctcatat acggtacacg tccccctgat ctgtcatcac ggtacacaga 44520
tttcgcccga ctgcggacgc cgacggccaa tcgcgtggcg taggagtggc gccccggctt 44580
cattataacg ccacgtcgga gcccctgcgc gccacaacgc cgtccggcgc aacttctgtc 44640
tcggcacggt acgataaaaa caacgtcccc cgtcgacgtt gttttctccg agcggtgatc 44700
gttcccgtcc ctctcctccc tccgcggccc ccacggcggc ggcctgctcg cacggaccta 44760
tactattacc gccccaccgc cgtcgtcgtc atgaacttca tcatcaccac ccgagacttc 44820
tccaacgacg attcagtcct gcgagccgcc gagatgcgtg acaacgtggc aggctcgatt 44880
tccaaagcgt acaagggcac ggtacgcgcc gaaggcaaga agaagctgct gctgaagcac 44940
ttgcccgtgc cgcccggcgg ctgctcgcgc cgcaacagca acctcttcgt tttctgcacc 45000
gagcgcgact accgcaagtt ccaccagggc atcgcacagc tcaagcgcgc gccggccgaa 45060
ctggaccccc acgagatcca gcaagtcacg gccagtatcc gctgccgcct gcagcccagt 45120
ctccgcgagc cgcccacgcc ggccgacgag ctgcagacgg ctgtgtcgcg cgtgtgcgcg 45180
ctcttcaacc agctggtttt cacggcccag ctgcgccact actgcgagca ccaggacaag 45240
gtggtgagct acgcgcgcga cgagctgact aaacgctgcg gcgaaaaatc ggcgctgggc 45300
gtggaagtgc atcaactggt agccctgctg ccacacgagc gccaccgcga actgtgccac 45360
gtcctcatcg gcttgttgca ccagacgccg cacatgtggg cgcgctccat ccgtctcatc 45420
ggacacctgc gccactacct gcagaacagc ttcctacacc tgttgatgaa ctcaggtttg 45480
gatatcgcac aagttttcga cggctgttac cacagcgagg cctaccgcat gctcttccag 45540
atcggtcata cggactcggt gtcggcggcc ctggaactct cacacggcgc ggcggccggg 45600
ccgcccgagg ccgatgaaaa caacgacgag ggagaggagg acgacgacga gctccgtcac 45660
agcgacccgg cgccgcttca cgagtccaag aagccccgca acgcccgtcg tccccgcaca 45720
cgcgtgccgc ctcacgagca aaagcccgaa gaaaacgagg aggaagaaga ggagctgttt 45780
ccctcctgca aggcaaccgc agcattcctg cgggcagaac cctccgtctc caacgacgac 45840
ggcaacggcg gcgaacgctg cgacacgcta gcgaccgccc tgcggcatcg cgccgacgaa 45900
gaagacggac ctctagccag ccagaccgct gtgcgggtcg ccgcgacccc ctcaccttca 45960
gtcaccccag cccttacccc cgtcacgtcc cccataaccc cgttgtgtat ttaacgtcac 46020
tggagaacaa taaagcgttg atttctcaag ttccgctctg gttttggttt cgttttcaaa 46080
gggagcccca tcatggccca aggatcgcga gccccatcgg gcccgccact gcccgttctc 46140
cccgtggacg actggctcaa ctttcgggtt gatctatttg gggacgagca ccggcgcctg 46200
ctgctcgaaa tgttgaccca gggctgctcc aactttgtgg ggctgctcaa ctttggcgtg 46260
cccagccccg tatacgcgct ggaggccctg gtggacttcc aggtgcgcaa cgcttttatg 46320
aaggtaaagc ccgtggccca ggagattatc cgtatctgca tactcgctaa ccactaccgc 46380
aacagccgcg acgtgttgcg ggacctgcgc acgcagctcg acgtgctgta ctcggatccg 46440
cttaagacgc ggctgcttag agggctcatc cggctctgcc gcgctgcgca aaccggcgtc 46500
aagcccgagg acatcagcgt gcacctaggc gccgacgatg tgacattcgg cgtgctaaaa 46560
cgagcgctgg tccggctgca ccgggtacgc gacgcgctgg ggctgcgcgc gtctcccgag 46620
gccgaggcgc gctatccgcg cctcaccacc tacaacctgc tgttccaccc accgcccttc 46680
accacggtcg aggcggtgga tctgtgcgcc gagaacctgt ccgacgtaac acaacgtcgt 46740
aaccgaccgt tgcgctgcct cacctccatc aaacgcccgg gctcacgcac cctggaggac 46800
gcgctaaacg acatgtatct gttgttgacg ctgcgacact tgcagctgcg acacgcgctg 46860
gagctacaaa tgatgcagga ctgggtggtg gaacgctgca accggctttg cgacgcgctt 46920
tacttttgtt acacgcaagc ccccgagacg cggcagactt tcgtcacgct ggtgcgtggg 46980
ctggaacttg cgcggcaaca cagcagtccg gccttccagc cgatgctgta caatctgttg 47040
cagctactga cgcaactgca cgaggccaac gtgtacctct gcccgggata tttacatttc 47100
agcgcgtaca agctgctgaa aaagatccaa tcggtctcgg acgcccgcga gcgcggcgag 47160
ttcggggacg aggacgaaga gcaggagaac gacggcgagc cgcgcgaggc ccagctcgat 47220
ctcgaagccg atcccacggc gcgcgagggc gagctctttt tcttctccaa gaacctgtac 47280
ggcaacggtg aggttttccg cgtgccagaa cagcccagcc gctacctgcg ccgacgtatg 47340
ttcgtggaac ggcccgaaac cctgcagatc ttttataact tccacgaagg caagatcacc 47400
accgagacgt atcacctcca gcgcatctat agcatgatga tcgagggcgc ctctcggcag 47460
acgggcctga cacccaagcg cttcatggaa ctcctcgaca gagcgcctct gggccaggag 47520
tcggaacccg agatcacaga acatcgcgat ttatttgccg atgtttttcg ccgtcctgtg 47580
accgacgcgg cttcttcgtc gtccgcgtct tcgtcgtcgt cctcagcatc tccgaattct 47640
gtttcgctgc cgtctgccag gtcgtcatcc acacgaacca ccacgcccgc gtccacgtac 47700
acctcggccg ggacttcttc taccacaggt ctcttgctct cttcttcctt gtcggggtcg 47760
cacggcatta gctccgcgga cctggagcag ccgccccggc aacgacgccg catggtcagc 47820
gtgaccctct tttcgcccta ctcggtagcc tacagccacc accgacgtca ccgaaggcga 47880
cgcagcccgc cacccgcacc ccgagggccg gcccacacac gcttccaggg acccgacagc 47940
atgccgagca ctagctacgg cagcgacgtc gaagacccgc gggacgatct ggccgaaaac 48000
ctacggcatc tctgaaagcg gtttttcctc tttttctacg tgtctgtctc aagatgagac 48060
gtcgatatca ataaaaatac cgtcgacgtg gtttttttaa cagtgtggtt ttctttattg 48120
actagcgaag tacacagttt acgagtagaa aagacaggga aaggttatat aaaatgctgt 48180
attatataca aaaacatgca cataaacaaa cgggaccatc gtgctcatca tcccctcctt 48240
gatcagttgt tcatgtaaac gtgtggcggg gtgaggggcg gcatgccgtt ggcggcgccg 48300
ggaataatgt gccgtcgacc gacgtcgcac accttgaaac gccgtcggcg cacgcagcgg 48360
tcgcaggacg ggatatccca gaggaagccc atgtaggtct cggggtcctc gtcgtgaaag 48420
cggtaggaga gttcaaagtg gtgcaacgag cccgtccgag ctcgcagctt ctggcgaaca 48480
ccctccacgt catcggtgca cagcgacagt gctgggctgt cacacagggc ctgaagctcc 48540
tgcggccaca ggtgcgtggc caggggcgag tccgtcgtca ccagtttgac gcagtgcatc 48600
aggttctcgg tgatggcgtc gtacaggcga ctctcagcct cctcgtgcgt catcacgttt 48660
cgaggcagcg acagctcgtc gtcgtcatcc tcgtcaaaca tgatcatggg gtcaggggtt 48720
tttttgggat gttgacaggt gggtgtcttt tccagacgca cgatggcctc acgccggccg 48780
ctgaaacggt ggtttcggtg tcccttcttt cccatgacgc aggtgaacat aaccacgtcc 48840
tcggccaaac ggtagacggc gtccatggcg gggtcgtagc cgtagacgac gccgaaagtg 48900
tccaccaaga cgtactggcg tacgaggaac tctttgcgtt ctggcacctc gtggcccagc 48960
gcgcccaaca actggtggta acaggtgatg cgcggcacgg tacggatcat gagctccatg 49020
gtctggatgc tgccgcccgc gcggacgacg ctgaaggatg tttccttgaa cttcataacc 49080
tctgtgttgt gggtccagaa ggcgaaatgg gtgtcgggac actcatcgaa agggtcgtcg 49140
atggtgtagg aagcgtagcc tcgcttggtc acctcggccg acaggctctc cacgtcaccg 49200
cggtagagca tgacggcgtt ccagtagtcg tcgtactgca ccatgggccg ctggtagtcg 49260
cgcatagtgt ggaagtggtc gcggtgacga aagccgttcc gcagaaagtc cttcatggtg 49320
ggtgccagct cgtagacgca gtcgcgcagg tcatcgtagc agtagatgcc gccgcgctgc 49380
ccgatgagca cgatgagttg gtagcgcata aagcccggac cctcgacgaa gccaaagggg 49440
tgcaggtact cctgacagca gacgtaagca cctggtagag aatagaaaaa atccacgcac 49500
gttgaaaaca cctggaaaga acgtgcccga gcgaacgtcc tctttccagg tgtcttcaac 49560
gacgtggggc ttaccttgcg aacagacggt gcccatcttg cccacgaagg gccccagggc 49620
gctgcgcgaa cggagctgga tgaagcagcg ttcgggccag gccacgtgca gccgggtgcc 49680
gcattcctgc tccagaaagt cgttgagacc gttaaagtcc ccggctcgga tggcgatgca 49740
gccgtaggcc atcagcgtgt cccgtaggtc gtccatgacg gactcctcta ccttcgctcg 49800
ccgacgctgc gcttctccag ccaccgctgc ggtcgacaga ctcctccgtc cgccttcgga 49860
gaactacggc gcggcggcac ggcctttata gacactatca gcgttgacgt cagacgatcc 49920
gatgaacgtc gttttttgtg ctggaacttc cctcgtcccg acaaatgtag cggaaatctt 49980
caagcaaatc gcgacgaagt ccgatgagga ggatgcaaaa gaggctgagc aacgcgatgc 50040
tgcccgccgc cacagtacat atgctcaaca acgcccagtg tcccaaggcg cgacttttgg 50100
ctcggaggag agccgaacgg cggtttctcc acatgacgga caacgtggtc cagtacgtcc 50160
atcctttgca ttccggtgtc cagacgggaa gcgttgtcat gttatttccc gtaactgtca 50220
cgttatgttt tgttttgttt ctcgtgagct taacggtcct cttgagaaat cgcgggcaca 50280
tgtcttgtag aaagatataa tcactttccg cgtatttcgt cagtgttgac atcacggtgg 50340
tagtgttttc tgaagaagta gcgttgtcag tgacgtttgt ttcttcccaa cgtacgtatg 50400
attcgaacgg actcgtgtgc gctattgccc gcaacacgta gctgtggccg gtgaagttga 50460
gcgtcagttg tcccacggtc acgttcgtgt cattcctaaa acatgctact tctccgtgaa 50520
cttccgtgac gtttatctca cgactctcgt tcaagacacg caggggaaac cagccttcca 50580
ggtgatactg aaaaccaaat ttaagcatga cgctgtgcca tttccgtcgt gattgattaa 50640
acgttacatt caagggcagt ctggcttcgg tcccgagaca ggggccgttg tagatttgcg 50700
tgtgattgcg tgtgcagttt aggtggcagt tcatgctcgt ggtgttggaa gtgcgattaa 50760
cgtccgtacc gtggtacgta catcggaccg aaacaccgtg tcccgtgctc caaagcagcg 50820
tcaacaacag ccacacagaa acctacgtgg agacgacacg ggacttttta ttgacggaga 50880
ctcacgtttc taccctcccc tttcccgtag gtaaaaaccc acgtttatca cacacgttgt 50940
ttttacctga aacccgcgca gcccgtggac gcgacaaaaa accgcggcac tagaaagaaa 51000
atgaaacaag tatgtttatt aagcagcatg tggggctaat aggggggata actgaggtat 51060
agcaactatg aaaaaatact acaaaaaaaa aagctgaaca tggtcatcta gcagcaaagt 51120
tctccttcta gaccacgacc accatctgta ccacgtcgcc ctccccggcc gtgtacacga 51180
catccttcac cacgaccggc ggcagcggcg gcgacgagga caactcgctc tcgacggagg 51240
ccgggacgac agaggacggg ggggtggtgg cggcggagga cgaaggggtg gcggcggcag 51300
cgggatcttc ttccgacacg ggcaacggca ggctcggcgg cgcggacagc acccgttgcg 51360
ccggggcgtg agaaggctga gccccggtgg cctggatgtg ggccaacgaa ttggctcgca 51420
gcgagtcgcg atccacgaag gtcataggaa ttttcccttc gcggatccgc cgctcagatt 51480
ccaggatggc gcgcacgtag ctgttcaccg acttggcaaa agtgcgcggc ccctccgtat 51540
tcttgtcgcg acgcgcttcc agcacctgct tttcgtagtc cagctggtgg aagaccatca 51600
ccaggtcgtc catagtgtgc gcgtgctgac ggacgtggga gcgcacctcc accgggaaca 51660
aagcgttcca atactccagc acgatagcac cgtgccagaa ctgcgccatg ctgggcgcca 51720
ggaaaaacag gataccggag tcgtaggcga acacgtccca cttgggcgtc atgaacaaca 51780
ccagctgacg cgtgggccgc accgaagctt cctcccaggc ctcgatgacc ccgaacatga 51840
tgagctcctg gtccaacggg gggcagtgtc gctccagcca actgatcttg ctcaggttca 51900
tctgcagaaa ctcgtacgaa gggtcgcaga tgcacacgta gagacccgag tcgtgccgca 51960
gcctggctcc gcgcttcatc agtttcctca ccgcgtagcg aagcgccacc ttgcccaacg 52020
ccgacgcctg gatcagtccc cccacgtcca tctgcgtctg tcgccactcg gcctcgtcca 52080
gcaggctcat gatagcggca gtgctatgcg tggtcgtagt catcctttct atccttctct 52140
atgaatagca gcaatagcgg taaagtccct tcttatacta tcccggagtc tgtggttttt 52200
ttgtttaccc ctgcttactg gtgagactgc tgggggccgt tgtgctgcag catccgagct 52260
cgttgccgcc gttgccacag gaaccggtgt ctccgcaggg cctttttgag ggcttcgcag 52320
gcttctcgcg caagtcctga gaggccctcg gcgtcgatgg ggttcacctc gggcgtccga 52380
gcctcgtttt cttcttcttc atcctccctt tcctcctccg tgtcctcccg ctctgtgtcc 52440
tccgttacgc tctcctcccc ggcctcggcc aagagcgcgg ccaccaagtc cacggaccgc 52500
tcggtctccg agttctcacc gtcaattacg ccatgttggc ggcgtaaccg gtgccgagaa 52560
cgccgggtga gcgcacatgc ttttttcttt cttaaccaag gcgggagagg atcttcaagg 52620
cgttttcgct ggatccagcg gtagctaaag taccaaaagg ccagcaggcc cacgctacct 52680
aacagattca cgtagactgg agacataatt aaagaaagaa gtgaaacccg cgtgtgggtc 52740
tcacgtcgtc ttgaaacacc gtcttatata catgaagatg ccggacatga cgcgcccaag 52800
acacgtgggg ttttcccctt aggcgacccg gtttcttaag atgtttttca tcttcgcacg 52860
cgatgtacta catcaaaggg tcggctgacc gaccgcattg acgcacagtt tccgagtacg 52920
cgcgtctcgg agcacctgac ggtgagccac ccaactcacg cggatagggg acaacactga 52980
cgtgaggggc gattcacgtc actgacggga ataagacggg tgagggattt ccaccttttt 53040
cttaagtgtg actctcttta cggtaaatcg cacctgtgac ctcttaaccc ctcctccctg 53100
gtacccgata accgtgaaaa acacacacca cacgtcacga caccgatcga ttttctttat 53160
tcttagtgtg atgataggta agggcactcg tgaggatgtg caattatcat tatcaagcct 53220
ttttcaaggc gtagtgatga tcgttgggca gaacccccag gctcctagcg atctgggaat 53280
agaaggagga gaacgagccc agggccagaa tgcccacagt gtacatggcc caggtctcca 53340
gaccgaacgt ggcgggtcgc agcttcagat ggtaggccac ccgctccgag agttgtgaat 53400
gctcgttcag gcaacaggac tgcaggtggg tgagcccaaa agcgctttcg tttacgccgc 53460
gcacgtgcac cgtctgggcc gggcaatcct ggtgttgcgc gcgaaagtgg tcctgacagg 53520
aaattccgtc tacgtggcgg cgcgtgttgt tacccacttc gatcaacaac gtgttatcgg 53580
caggatgatg cgagaacgcg acgacggtgt tgttggaggt ctggcggcaa cagtacacgt 53640
cgagcgtcat gagggccatg tcgccttggt ggtacacggc gtacgcccaa ccctggaaca 53700
cgagcggaca taacggaccg tgagcggacg tcacggcggc ggttgttacc gtcgtctcgg 53760
caggagaaca caataaactc ctgatcctca tacacaggag tccaaccgtc agaattaaag 53820
tccgcggagc cataaccgcg caagtgaagc cgatacgagt gttgctgaat ttgttcattc 53880
tgccgactgt tgctcacgag cgttcggagg cggtgccaca ggctgttggc cattaaaaag 53940
tcctggcccg aatgacgaca agacagagcc cgaggcgaag aaaaaggcgc ccgtcatgaa 54000
gacgtaggca ggggaattcc catattttta tggcttcttt taaaagtctg tatccgactc 54060
catccggcgc ttttcccaaa ccgtggtctc ctcgtcgtcc gactcggtac ccaggaggtg 54120
gtaagtcttt tgccgcacgt agaaagcttt caacgtggag caaaagatga gaataaagac 54180
cccgaaaacg aaacaaacca cgccgatcat gccgatgcag acgttcatgt cgacgtagcc 54240
ggcggtgctg ttggcggtgc ggcaaaagag tgtcatgtcg tgcgtgcaca aaaaacaaca 54300
cacaccacag gccaggtcgt agcgtagtta ttattccgta gcagcaatga tggtacagtc 54360
aagcacatgc tctatccccg ttaccccgat gatgcttgcg tccccgttgt tatattggca 54420
ctgtcccggt taatcaccac ggtgaacacc acggccaaga aaatgatccc taatatagcg 54480
accactaaga gagcaaaagt ccatttccag ccgttgtcaa agtacgcccc cgtggtggga 54540
tgcatggtgg cgggcatttc catcatgtcc atgtcgaacg tgtgtcgcgg cgacggcgaa 54600
ctaaccaggc aggaacttgt cgcagcacag gaaggtcttc tccaaacctt taatattgag 54660
atgtccaaag taaccaacgc gtaacaggtc gcagtaggtg aagaaccaac cgtttggcca 54720
gctgagacgc agcaccgtgc cgctgacgcg acgaaccagc ttctgcaggt ccttgcgagc 54780
gtcggaggtg acagagcagc ggaaggtctc gttaaccagc tcgacagcca gcgcgtcctc 54840
cagcgtgcgt tccttcatct cgtcgttgat gctctgacgg cgccgccgga tttcgtcgaa 54900
acgggccgcg gaggcggcga ccgacgcgga ggtcgtccga acgccctctg tgacgctgcc 54960
gtccggccag tcaagaaagc taaggctggc gctgcgccgc ctaaagtgtc cgatccgcgc 55020
gggacgtcgc tgagggacgg tggctggtct gctggggcgg gtacggccgc gggtgtccgc 55080
ggacacgtta gttatacacg gaattgagtc acgtggcacg ttgccagctg aaaccgccgt 55140
cgtctccgcc ggcgttttct ccatcacggg accgcgccgt gcgcgcgttc ccaggcacgc 55200
ggcccgcgct ctagccgcac ttttgcttct tggtgttagg gacgaactcg aacgttacag 55260
aatcctcgct gtcgctctcc tctttcgcgt cgttgaagta attgccggag ttgcgatcca 55320
aaccgccgcc tcctcctcct ccgccgccgc ccgatccacc tttggacgtc aggtagctgg 55380
tgatcttgtg ctgctcgtat ttttccttgg aggaaagacc gtggtcgtga tcaccgccgc 55440
cgccaccgct gctcattttc cgcgtaccgg aaccaccgcc gccaccgcgg tcgtgcttct 55500
tgccgccacc gccgccacct cctcccagac cgccgagacc catgggctcg ttcatgagat 55560
cgttatccag acccgggccg tcgtcatgca gaccgccggc attggccagc gaagagaggc 55620
tgccgccacc accgccgccg ccacgcgact tgccgctgtt cccgacgtaa tttttgtcga 55680
agggatcgcc acgctggaaa ggttcctcgg tgagaaaatt ctccacggcg aacagaccgt 55740
tgcggctggc cacgtacaac agcgtgtcgt gctccgtaac tatacgcaac gtgcacggca 55800
gtttggtgac ggcgcaattg agcagcgtct ggtagaagtt cttcagctgc acgttgatac 55860
gcatgttttt cacgccgtgg aaactgacgc ggttattggc tgtgaattcc agctcgctgc 55920
cgttggtcag gataaacttg atggccggtg gaccggcgtg caccagaatc tgcacggtgc 55980
ccgtagggca gggcgctttt ttaacgttac gcttgacgcg ggtatgcggc ccgatccact 56040
taagcaggtc ggccaccacg ccgaaatcta gatccacgtg cacggccgaa ttctcgcttt 56100
cgcgcacaat gtcttggccg tgcacgcagg ccgagctgaa ctccatattg aaatcgggcg 56160
cgcacatgga gatcttggcc gacaggtccg agatgtcctg cacgtagaac ttggtcaggt 56220
ccttgctgga agtcaggtac atgaaattac ccagcagcgg cgtggaattg ttaatggtct 56280
tgggctgaaa cgacttgtca gtgatgtaga ggcatgagct gttaaaagtg atttttgaca 56340
cgcagtgact gcgtaccgtt tgcaagataa gcgacggcgt gggcaagaag gtaaccgtgg 56400
tgttctcctt gagcgcacgg atcacagatc gcagctgctg gatagccgtc ttgtacggct 56460
tcagccgcag cgccagcgtc ggcggctccg agaggcgcgt cttgcgatcc atcccggaca 56520
gcgtgcaagt ctcgactaag gagcgggcgc gagcgagcga aagttttata gagagcacac 56580
acgacgaccg ggaacgctgc gaagacgccc ggcgtctaat aatacagccg cgccgagcca 56640
gcgggccccc gactaagagg cacagtactt atatactccg accttaaagc gccagtggta 56700
ccacttgagc atcctggcca gaagcacgtc gggcgtcatc cccgagtcat agtagaaaac 56760
cagggccacg cactggtcca caaacacgct caggttcacg gccgccattt ccacgtcgtt 56820
ttggatcgcc ggtgccgcct ggaacagaca ctgcgtcgcc ttgccctcct cctggtgctg 56880
ctccaaccac gcgtaattca ccacgggcac gcgcagcggc ctccgcacca cggtggggaa 56940
gtaacactca cggttgggcg ggcacaatga ccacaccgtc tcctcctcga acacggtgcc 57000
gcgcgaagcc cacactgacg gcgtcacgcc ccacagatgc gccacctcgt cgtcgggacc 57060
caccgccaga aactgacagt tgcgcaatcc gaactcgagc atgtcggcgc gcagcgcttc 57120
ccagcgcgcg ctggcgatgg agagccgcgg caaccgatac aattcgaaaa tgaatttgcc 57180
ctcttgatag atggtgcgtt cgaaccactc gcagcgcggc aaacccgact tgcacaaatc 57240
gacgctagcg cgcaccgcgg caaagtacat gtgctcaaag atgcgctcga tcaagtccca 57300
agaggcaaag tacgtgaacc ctaaccgcat gagcgccgtg tgcaagccag ccacgccgat 57360
gtgcagcgga cgcagttttt ccagcgcgct ctctacccac cattcggacg ccgacattag 57420
cgcgtccaag cgcgcgttgc cccaaaccac cgcctcggtc accaactcgc gcagcacgct 57480
caaatcaaag taacgtcgcg tgttccccaa aaccacgtcg ggtagatgca gcttctgctc 57540
gtcgctacgc gcaaacacgc agcgagccac gttcaccgtc agccgctgca ccggcatgtc 57600
acactcgcca aagtggcacg acgccatatc gggactcaag cacggcggca ggcacacgct 57660
gtcggccata atcgagtact tgactacgtg atggacaaag accaccgagg cacggccctt 57720
gagcgcgcac agcaacatct ttttcagaaa atcgtccgtg ttcacgacca ccttggggca 57780
cgattgctcg cagcgcgaat actctttctc gaaagccgac tcctgaccca ggtccgagag 57840
ccgccgggag acaggccgcc caaacagcga gtagcgctgc tcacgcgcac ggtagcgctt 57900
cattaacacg ctaggcacgt tgaaagcgta gcaaaccccc gtcaactccg acgtgctttc 57960
tttgagaata aagttaatca cgcggatagc ggccacgtcc cacatgtcca caaacacacg 58020
taccacgggt cgatgcacct ccttctcgcg tatcaaatcg cagtatcccc ccaggcaacg 58080
aatcacgctg ttcacatcgg cgttaagtcg cgttacgttc accgacacag aaacgccgca 58140
actcaaggta ctcatccact tgcacatggc cgcccaactg gcgtcacgcg agaaagggtc 58200
ggccgagatc agaaagtcgt actgcggcac gcgatcgaaa cccacggtag acatggtgaa 58260
ggtggacagc gacagctgcc catcgcgaca gcgcttcaac accgattcca acacctcgcc 58320
ctcgaaacgc gcatccagat ggaaacgata gatgcgcgag tgcctactgt tctcgatagc 58380
ggccgtcaac gccacggcga tgcgcaaaaa cacgccgccc gggctctcgt cctgtccgtg 58440
cagttggcga cacaccttat ccaaacacaa aatggccgcg tacaagcccc agcaaccggc 58500
caattccaca aaacgcgccg tctcctcggc cagcttgggt agatcctcca tgtgacgcag 58560
cacaaaacgg cgcaccgact catcgcacag ctccgaagcg taacacagtg gcgtgcggct 58620
ttcacgcgcc cagttggctt tgaaataaaa gcgacccaac agcaggtcgc aacgcggcga 58680
gtgacgaatc agacagggac cgtggcgcat aatgagctga aatagcctga aactgcccaa 58740
accggcactg tgccgcgaca cggtgtccat ctcgcgccac agcgcgttcc tgtcggacgg 58800
cagctcccgc gccggctcct gtacgccgca aaagcgaaac ttgccccagt agccgtgaca 58860
atgacacttt ttgcccatca acatgcgcgt agcttgtatc ggcggcgata ctttgcagag 58920
cgaagccccg aaatcgtcct cctcctcgac actgtccagc tccatcctgg tcgcgccggc 58980
cggattaaag gtgctcagac cgctactcac gcgtccaccg cgactgggca cggcgggacc 59040
gctgtcacgc gtcaacgaca gcacagacgg cgtgccgtcg ggagacggcg actcgggacg 59100
ccaactgacg acgccgccac cactcgtaaa acccgctaca catgctacac cgctcgatac 59160
gttggtattt ccagcggacg cttccttgtc acccccgggc agcggcccct cctcgagctc 59220
gctgtcatct cccccgatag tatcagcggc gacctctgcc gacgattcct ccgtctcggt 59280
ttccgcgctg cggcttggaa tcctacctgg ccggcaccga tgtgcgggca ccgaggacac 59340
ccgctgttcc tcgtccgcgt cagccggatt cataagttta cgaggaaaat aacaaagaaa 59400
tcaggtagat ttcaataaag tgagtctaga tggcgccgac aactacggtt tataaagtct 59460
gtgtgcgatg tgtttttttc ttctgtgtct cctccccgta tgctgtcagc gccgctcaga 59520
cgaattctcg aaagtctccc aattcgacgc taaagttgtc caaacggacg acggacagtt 59580
tgagttcttt gtgtaccagg aacgaggtgt gaatgtcgtc agccaggcac cagcccagct 59640
tttgtatgac cccggtacac agagggatct ggcgcgggcg cgtgatgcga cggttgacaa 59700
agctacagcg ctcgcgggcg aactttccgc gtgcaacgtc gaccaaggtc tgccagtgtg 59760
cgatgctgga ggtgagcacg tagatgccgg gacgtgtttc gggcccgtca tagtcataga 59820
cgatgattaa atacacgtat tgcagccgtc cccgggtctc ttcccacgtc aggtacatgt 59880
ctttcggtat catcaacgcg aacacctccg ttttgagcgt gttgtaaagg tagccgcgca 59940
tgacgcaggt gagcaacgag gtgatgccca gcgagacggt cttgacgcag cccagcgtct 60000
cgaggcggcg gtgcagcaga tgcgggccca ggtccagcca ctgcagcgcg gcgcgcgcgg 60060
ccgaggccgt gtacacgctt tcgagcaggc agcgcgtgct ggccgagacg ttggaggcgc 60120
gaatgcctaa caggtaaagg ctaatgtaga ggtgtcgcgg cgagtcgcaa cccgtctcca 60180
tgcggatgag cagcgcgccc ggctgcgcct cgaactctac caggccctcg ggcacgaaga 60240
aacgcgccgt gagcgcctgg tgatcggcgt ggtagagata gcgaaccgat atagtattta 60300
cctcgcgttt ggctttgagc gccgtcacta gttcattgtc ctcgtcggcc gggtcgcgcg 60360
gccgtttggc caccgcgcgc gcgtccatga tggcgaggcg cacggtagat ttcaaaaagt 60420
tgatagagca gctgcgggca cgggccacgg acaaagcgga ggcgttaaat accgtgagcc 60480
aattggagat cggcgcggtg gatgcccagg acgtgaccgc gagcgccgtg cgcgccttcg 60540
tgggtgcgtt gccgagctcg ggctaccact ttggcttcgt gcgtcagaac gtggtctttt 60600
acctcctaag ccacgccacg gtacagacgg cgcgcgaccc gctgtacgcc gccgagcagt 60660
tgcacgaaca gctggaccgc ttcctgcgac accagcacga cggcggcgga gacgaggacc 60720
ggttgccgtt ctaccacaac ggggccacgc tgacggcttt ccagaagctg ttgcagaccc 60780
tgcgcgagat ccagaccgta atagccgaac agagcggcgg caccgcggcg gcggcggact 60840
tgatcgccag taacaacgcg tcgaccgagc gccgcggcaa gaagggcggt tcgagttccg 60900
ggggccagca gccgctggtc cgccgggtga tcacgcagct ggaaacggct gccacggagg 60960
cgcggcccta cgtcaattgt cgcgccgtgg ccgaactcct ggacctgacc taccagcggc 61020
tcatctactg ggcctgcacg ctcatgccct acgtgttgtt tcggcgcgac accgacaccg 61080
aactggacac ggtgcttctg atgcattttt tttacacaca ctaccgttcg gttaacggcg 61140
atttggccgt ggagtttcaa aactacgtca agaacagcgt gcggcacatg agctctttcg 61200
tcagttccga tatcgacggc gaccagaagc ccggtgccga acacatgcgt gacgtcagct 61260
acaagctgtt cgtgggtaat ctgcaagcgc gtgacgccag cggcctcatg tttcccatca 61320
ttagcacgcg catctccacc gtgaaccttt acctgtcgcc cgaacgtatg tttttccacc 61380
cgggtctgat ctcgcgtctg ttgagtgagg aagtttcgcc gcgcgccaac ctagacgctt 61440
acgcgcgcgt gtgcgatcgc gtgctggaag accacttgca tacgccgcga cgcgtgcaac 61500
ggctactaga tctgacgcag atggtaatgc gactggtgga actgggtttc aatcacgata 61560
cctgcgcggc ctacgcacaa atggcgctga tccagccggc cagtcagaag agctcgctct 61620
ttgtcagcga gattcgcgag aaactcatac agatcatcta caatttttac acgtttttca 61680
tgtgcctcta tgtgtacagc cccacgttcc tgttcgacca ccggcggcgg ttgattttgg 61740
agcagcatcg atccacgttg atcggctcca aggaggaact acagcacgtc tggagcaacg 61800
tgacactgaa cgtcaatacg cactttgcgg ttcagtacac ggaagaagac tttgaggcac 61860
atacgaaggg tgccacggag gcggagcgcg agtacctgta tcgggacctg cacagcaagt 61920
ggggcgtgca cctgtttacc ttgcgtccgt ctcgcggcgc ggccggcgcg gcctcgcctt 61980
tgcctccgct tgacggcgtc acacgctccg acatcttacg cgaatgcgcg ctcgttaatc 62040
tgaacgaagg ccgcgtcaac tacgcctccc tgctagcctt cagccatcat cccgagttcc 62100
ccagcatctt cgcgcagttg gtggtggtaa ctgagttctc ggagatcttt ggtatcccgc 62160
agggcctgtt tcaagccgtg ggttcgccgc gtcttttcgc actcattcag ctgtgccgtg 62220
tattgttgcc cgagcaggtg acgctgtacc agaacctggt ctccatctac aacctgacca 62280
ccttcgtcaa gcacatcgac gccgcggttt ttaagacggt acgcgattgc gtcttcgaca 62340
tcgccacgac tctcgagcac ctcagcggtg tacccgtcac gcccaatgtg gacctgctgg 62400
ccgagctcat ggcgcgctcc gtagcgcata acctgtacac caccgtcaac ccgctgatcg 62460
aggacgtgat gcgcagcagc gccggcagtc tgagaaacta tctgcgacat acgcgactct 62520
gtttcggtct ggcgcgtggc cgggcgcgcc tctcggagga cggcgtgacg gtgtacgtgg 62580
aggtacaagg tcaatacgga ctacgcgtac ccaccacgcg tttcgtagaa cagttgcgcg 62640
agctggttcg ccgcgatcgg ctgttggccg agaatctgcg cggcttgaac gagcgcctgc 62700
tgagtgttcg cgtgcgcgta cgtcagatca gcagcgacac agaggaagta agccgacacg 62760
ccaagggtca ccgcacggtg gcccagatga gcaaggcgct caaaaagacg gcctccaaaa 62820
tcaaagtgtt ggaaacacgc gtgacattgg cgctcgagca ggcgcaacgt tccaatggcg 62880
ccgtcgttac cgcggtgcaa cgcgcgctag ccgtctttga cgtactaagt cgcgagaact 62940
tggaacgccg cggcgcacag ctctgtctga cggaagcgac gagcctactg caccgacatc 63000
gcgcgctagc gccgatgacc tggcccgcgg gcacgggcgt tgcggcggcg gccgaagcgg 63060
atcgcgcctt acgcgagttc ttggaggcgc cctgggaatc ggcgccccaa ccgccgcgac 63120
tccgcatgac gcccgacacc gatcacgaag aatcaacggc aggcgcgacg tccgtaccgg 63180
aggtcctggg tgcgcgctac gaacccgcac acctggccgc gagcgaccta ttaaactggt 63240
acatcgtccc cgtaagccag gcgcagcagg acatcttgtc ttcgatcgac ccgcccgccg 63300
gctcgacatc ggtgtccctg ccgccggcct cgccatgaaa gtcacacagg ccagctgcca 63360
ccagggcgac atcgctcgct ttggagcgcg agcgggcaat caatgcgtct gcaacggcat 63420
catgttccta cacgccttgc acctgggtgg aacgagcgcc gtcctgcaga ccgaggcgct 63480
ggacgccatc atggaagagg gcgcgcgtct ggacgcgcgg ctagagcgcg agttgcaaaa 63540
gaagctgccc gccggcgggc ggctgccggt ctacagactg ggcgacgaag tgccgcgccg 63600
cctggagtcg cggttcggcc ggaccgtgca cgcgctctcg cggcccttca acggcaccac 63660
cgagacgtgc gacctggacg gctacatgtg tccgggcatc ttcgactttc tgcggtacgc 63720
gcacgccaaa ccgcgtccca cctacgtact cgtcaccgtc aactcgttgg cgcgcgccgt 63780
ggtcttcacc gaggaccaca tgttggtctt tgatccgcac agctccgcgg aatgtcacaa 63840
cgccgccgtg tatcactgcg agggtctcca tcaggtgctg atggtgctca cgggcttcgg 63900
cgtgcagctg tcgcccgctt tctactatga ggcccttttt ctctacatgc tggatgtggc 63960
gaccgtacca gaggctgaga tcgccgcgcg tttggtctcc acctatcgcg accgcgatat 64020
cgacctcacc ggcgtcgtcc gagaaagcgc ggacacggca gcgacaacga ccaccgccgc 64080
accttcctta cctccgctgc ccgaccccat cgtcgacccg ggttgccctc ctggcgtggc 64140
gcccagcatt cccgtctacg atccctcgtc ctcacccaaa aaaacacccg agaaacgccg 64200
caaggacctc agcggtagca aacacggagg caaaaagaaa cccccgtcca cgacgtccaa 64260
aacactggcc accgcctcct cctccccctc agcgatagcg gcggcctctt cttcgtccgc 64320
ggtaccaccg tcctacagct gcggcgaagg ggccctgccg gccctgggcc gctaccaaca 64380
gctggtcgac gaggtagagc aggagttgaa ggctctgacg ctgccgccgt tgcctgccaa 64440
caccagcgcc tggacgttgc acgcggcggg taccgaaagc ggcgctaacg cggcaacggc 64500
cacggcgccg tccttcgacg aagctttcct caccgatcgt ctccagcagc tcatcatcca 64560
tgccgtcaat cagcgctcgt gtctgcgtcg cccctgcggt ccgcaatcgg cggcgcagca 64620
ggcggtacgc gcctatctgg gcctatccaa gaaactggat gcctttctgc tcaactggct 64680
gcaccacggc ctggatctgc agcgcatgca cgactacctg agccacaaga ccaccaaagg 64740
cacgtactcg acgctggatc gcgcactgct ggagaaaatg caagtcgtct tcgatcccta 64800
cggacgtcag cacggcccgg cgctcatcgc ctgggtggag gagatgctgc gctacgtgga 64860
aagcaagccc actaacgaac tgtctcaacg actgcaacgt ttcgtaacca agcgaccgat 64920
gcccgttagc gacagcttcg tctgcctgcg acccgtagac tttcagcgtc tgacgcaggt 64980
catcgaacag cgacgtcggg tgttgcaacg tcaacgcgag gaataccacg gcgtttacga 65040
gcacttggcc ggcctcatca ccagcatcga cattcacgac ctagacgcca gcgatctgaa 65100
ccgacgcgaa attctgaaag cgctgcagcc gttggacgac aacgccaagc aggaactctt 65160
tcgcctgggc aacgccaaaa tgctagagtt gcagatggac ctggaccgtc tgagcacgca 65220
gctgctgacg cgcgtgcaca atcacatcct taacggcttt ttgccggtag aggacctgaa 65280
gcagatggaa cgcgtcgtcg agcaggtact gagactcttt tacgacctgc gcgacctgaa 65340
actgtgtgac ggcagctacg aagagggatt cgtcgtcata cgcgaacaac tgagctacct 65400
catgacgggc actgtgcgcg acaacgtacc gctactgcaa gagatcctgc agctgcgaca 65460
cgcgtaccag caagccacgc agcaaaacga gggtcgcctc acgcagatcc acgacctgct 65520
tcatgtcatc gagacgctgg tgcgcgaccc gggcagccgc ggctcggcgc tgacactggc 65580
cttggtacag gagcagctag ctcagctgga agcgctaggc ggcctgcagc tacccgaagt 65640
gcagcagcgc ctacagaacg cgcaactcgc gctaagccgc ctctacgaag aggaagagga 65700
aacgcagcgt ttcctcgacg gactctcgta cgacgatccg cccaacgaac agaccatcaa 65760
gcgacaccca caattacgcg agatgttacg tcgcgacgaa cagacgcgtc tgcgactcat 65820
caacgccgta ctgagcatgt tccacacatt agtgatgcga ctggcgcgcg acgagtcgcc 65880
gcgaccgacg ttttttgacg ccgtcagttt gttgttgcag caactgccac ccgactcgca 65940
cgaacgtgag gatctgcgtg ccgccaacgc cacgtacgcg cagatggtca agaaactgga 66000
gcagatcgag aaagccggta ccggcgcatc cgaaaaacgt ttccaagcgt tacgggagtt 66060
ggtttacttt ttccgtaatc atgaatattt ctttcaacat atggtcggac gactgggcgt 66120
cggacctcag gtaacggaac tctacgagcg atatcaacac gagatggaag aacagcacct 66180
ggaacggcta gaacgtgaat ggcaagaaga ggccggcaag ctcacggtaa cttctgtgga 66240
ggacgtgcag cgtgtcttgg cccgggcacc gagccatcgt gtcatgcatc aaatgcaaca 66300
aacgttaacc accaagatgc aagacttttt agacaaggag aaacgtaaac aggaagaaca 66360
gcaacggcag ctactggacg gctaccaaaa aaaggtgcag caggatttgc aacgcgtggt 66420
ggacgccgtt aagggcgaga tgctctccac catcccgcac caaccactgg aggccacact 66480
cgagctgctc ttgggcctag atcaacgcgc ccaaccgcta ctagacaagt tcaaccagga 66540
cttgctgtcg gcgctgcagc agctgagcaa aaaactagac gggcgaatca acgagtgtct 66600
gcacggcgtg ctgacgggtg atgtagagcg gcgctgtcac ccgcaccgag aagcggctat 66660
gcaaacccaa gcctcgctaa accacttgga ccaaattttg ggtccgcaac ttctgatcca 66720
tgagacgcag caggccctgc aacacgccgt ccatcaagcg cagttcatcg agaagtgtca 66780
acagggcgat ccaactacag ccatcacggg cagcgagttc gagggcgact ttgcacgcta 66840
ccgcagcagt caacagaaga tggaggaaca attacaagag actagacaac agatgaccga 66900
gactagcgag cggctagatc gctcgctgcg ccaggatccc gggagcagct ccgtcacgcg 66960
tgtacccgag aaacccttca agggtcagga gctggcgggt cggatcacgc ccccgcccgc 67020
cgacttccag cagcccgttt tcaaaacgct gctagatcag caggccgacg cggcccggaa 67080
agcgctcagc gacgaggccg atctgctgaa tcagaaagta cagacgcagt tgcgacaacg 67140
cgacgagcag ctgagcacgg cgcagaacct gtggactgat ctggtcacgc gccacaaaat 67200
gagcggcgga ctggacgtga ccacccccga cgccaaggcg ctgatggaaa agccgctgga 67260
gacacttcgc gagctgttgg gcaaagccac gcaacaactg ccgtacctgt cggcggaacg 67320
cacagtgcgc tggatgctgg cctttctgga ggaagccctt gcgcaaatca ccgcggaccc 67380
tacgcacccg catcacggaa gcaggaccca ctaccggaac ctgcaacagc aagctgtcga 67440
gagcgccgtg acgctagcgc atcaaatcga acaaaacgcg gcctgtgaaa attttattgc 67500
acagcatcaa gaggcgactg ccaacggcgc gtccacgccg cgggtcgaca tggtccaggc 67560
ggtggaagcg gtctggcagc gactggaacc cggacgcgta gccggcggcg ccgcgcgtca 67620
tcaaaaagtg caggaactgt tgcagcgctt gggtcagacg ctaggcgacc tagaactgca 67680
ggaaacgttg gcgacggaat actttgcgct gttacacgga atccagacct tcagctacgg 67740
gctggacttt cggtcgcagt tggaaaagat ccgcgatctg cggactcgtt ttgcggaact 67800
ggccaagcga cgcggcacgc gtctctccaa cgagggagtc ctgcccaacc cccggaaacc 67860
gcaggcgacg acttcactgg gcgcctttac acgcgggttg aacgcgctgg aacgacacgt 67920
ccagctgggt caccagtatc tgctcaacaa gctcaacggc tcatcgctag tctataggct 67980
ggaagacatt cctagcgtgc ttccggcaac acacgagacc gaccccgcgc tgataatgcg 68040
cgaccgcctg cgtcgcctat gcttcgcgcg tcaccacgac accttccttg aagtggtaga 68100
cgtcttcggc atgcggcaaa tcgtcacgca ggccggcgaa cccattcacc tggtcaccga 68160
ttatggcaac gtagccttta agtacttggc gctgcgagac gatggtcggc ccctggcatg 68220
gcggcgccgc tgtagcggcg gaggactcaa gaacgtcgtc accacacgtt ataaagccat 68280
cacggtagcc gtggccgtct gtcagacatt gcgcactttc tggccacaga tctcgcagta 68340
cgacctacga ccctacctca cgcagcatca gagccacacg caccccgcgg agactcacac 68400
gttgcataac cttaagctct tttgttatct ggtgagcacc gcctggcacc agcgcatcga 68460
cacgcagcag gagctgacgg ccgccgatcg cgtaggcagc ggcgagggtg gtgacgtagg 68520
ggaacagaga ccgggccgcg gtaccgtgct gcgcctgagt ctgcaagagt tttgtgtact 68580
catagcggct ctgtaccccg agtacatcta caccgtcctc aaatacccgg tgcagatgtc 68640
actaccctcc ctcacagctc acctacatca ggatgtgata cacgcggtag tcaataacac 68700
acacaaaatg ccccccgacc acctccccga acaggtcaag gccttctgta tcacccccac 68760
ccaatggccc gccatgcagc tcaataaact gttttgggaa aataaactgg tacagcaact 68820
gtgccaggta ggcccgcaaa aaagcacacc gcccttaggc aagctatggc tctacgccat 68880
ggccacgctg gtctttccac aagacatgct gcagtgtctg tggctagaac tgaaacccca 68940
gtacgccgag acatacgcct cggtgtccga attggtacag acgttgtttc agattttcac 69000
gcaacaatgc gaaatggtga ccgaggggta cacgcaaccg cagctcccca ccggagagcc 69060
ggtgcttcag atgatccgcg tgccacgtca ggacacaacc accacagaca caaacacgac 69120
cacggagccg ggacttttag atgtttttat tcaaacagaa accgccctag actacgcgct 69180
gggctcctgg cttttcggca tacccgtgtg tctcggcgtg catgtagccg acctgctgaa 69240
aggccaacgt atactagtag cgcgccacct cgaatacacg tcgcgagacc gcgacttcct 69300
ccgcatccaa cgctcccggg atctcaatct cagtcaactg ctccaggaca cgtggaccga 69360
aacgccgctg gagcactgct ggctacaagc ccaaatcaga cggctacgcg attacctgcg 69420
tttccccacc cgcttagagt ttattcccct agtcatttac aacgcacagg accacaccgt 69480
cgtacgcgtg ctgcgaccgc cctccacgtt cgaacaggac cacagtcggc tggtgttgga 69540
cgaggccttc cccaccttcc cgctgtatga ccaagatgat aactcatccg cggacaacat 69600
cgctgcgtct ggcgccgctc caacaccgcc ggtacctttc aaccgcgtgc cagtcaatat 69660
tcagtttctg cgtgaaaacc cgccacccat cgcgcgagtt cagcagccgc cgcgccgaca 69720
tcgtcatcga gcggccgcgg ccgcagacga cgacggacag atagatcacg tacaagacga 69780
tacatcaagg acagccgact ctgcattagt ctctaccgcc tttggcgggt ccgtctttca 69840
agaaaaccga ttgggagaaa caccactatg ccgagatgaa cttgtggccg tggcgcccgg 69900
cgccgccagc accagtttcg cctcgccgcc tatcacggtg cttacgcaga acgtcctcag 69960
tgctctagaa atactgcggc tagtgcgatt ggacctgcga caactggcgc aatccgtaca 70020
ggacactatt caacacatgc ggtttctcta tcttttgtaa ccgacactga cagtagcggg 70080
taataaaaac aataggattt ttatcgtttt tttatgttac aaaacaacgt atcactttca 70140
cggtgattta ttcttgctat tccttttccc cttgggctgt cagcgccggg tgcgcgacac 70200
ggctaccatg cgcaacaggt ccagcttaaa ggcgcacttg tcattaaaca ggctggacat 70260
gcgcgtgtac ttgctcagca tggtggccaa caccgggtgg gtggcctctg atatctcggt 70320
cggcagctcc aaaacgacgt taacgacgtg acggtgtttt tcgtcccgct tgttggccac 70380
cgtgggtccc ggcgcggtgt tagacatggg gcaggccgtg gggggaggac gaagaggaag 70440
ccgctgctaa accgccgcgc gcctgctgca caatgtggcc gccgacgtgg caggcggtct 70500
gtttaaccag cgcgcagccc cgacacagcg gggcgccgtc ctcgctttcc aaacagctgt 70560
cgcggtactc gcccgtctga cagcgcgcgc acagcaggcc gtgcccgtgc gaagtgaggc 70620
gcaggagacg cgggaccgtc acgtcgcgta ccaccacagt ggagtcgcag gtgcgtgccg 70680
cgcagggcag aatgacgtcg aaagccagcc ggtgatcgta cacggcacaa gccgcgttga 70740
ggcccagcac ggctttccag cccacgcgta cgcagcgctg tccaaagagc gtctcggaga 70800
cgagctcgta gacgcgctgc cgcaccaccc gctgactgcc gcagagcgag cagtgcacga 70860
gctcggcgtg cgtgttgaag atgacgctct tttcttgacg gtcccgataa tagaacatcg 70920
agttgagcgg aaagttttgc tggcagtgta gcttttcctt acccaggttg aggcagtgtc 70980
cgcactgccg acagaccacg gccaccagcg agcgcgcgtc cagatggcgc tcgcacttga 71040
gtcgacacag acaccagagc ggcaggtcga tgacgctgcc gatgaggccg ccgcgcagcg 71100
cggcgctgag tgcaaagagg acgatcttgg tgggctctac gtgacgcgcc tgctgtccgg 71160
cgcccgcgtg tcctaccgcc gcagctgccg ccgtcgagcc tcctccgcgc gtctcgtcgt 71220
gcagacccag tgcccgcaac ggcaccaggt atcgcggaca cgtgtcgcaa aacgtctgca 71280
ccgcttgtcg ggccagtacg tagagcgggt ttccgcaggg taccttcccg gcgtaccggc 71340
gcaaggctgc gatgaggccc cgcaactgcg gcgaccgcgg ctgccgttgg tgacaccact 71400
ggttacggtg gtatacggcc aaatcagcgc gggcgtcgaa gcgcttggcg cgtagtaatg 71460
ctaggcacgg cgagctggtg gggtgaagca cgggcagccg aaggtccacc ccgaaaagga 71520
aacggtgaag gtcacctagc agcgaggcgg tgacaccgtc caacaacgcg tgcagccgct 71580
cgggcgggta gagccgcaga cggcgcagca ggtagtcggt gtcgtagcgt tcgaaacgca 71640
gaaaggccat cgtgcggacg gccacggtgt gcagacagtc catgctgtag acgtaagcga 71700
gaaacacaaa gtagggcttg gtcataacca tacgctgaaa gagcgccgtc accgcctccc 71760
gctcggcttg ccgacacacc agccattcgc gcaggaagcg ttggtagaga cggtcgccca 71820
gctcgcgatt cagaaagcgc ttatccgtca cgaagagatg aaggacgcaa gaacgtggca 71880
cgtgatgcac cagctgctgc tggaggaccg ccgacgtctg cgccgcaaac tgcgccggtg 71940
gctgcgacgt ttctaccgcc gcttcctccg gctgcagcgc accgcggccg atcaccagct 72000
gcacatggaa atggtcctcg tgaacgcaga ggggcgcgaa gagacggcgc agagcctggt 72060
ggaactcatc agtcgcggtg tgcggagcgt gtcggagacg acgactggcc atgaccgcgc 72120
cacagcagag ccagcaccag cagaagagcc agcaccagcg ggcccagagt cgcaaagcgc 72180
gcgggcagcc acggcccaga ctgcggtcgc gatggcccgg agcgcgctcg ccaccacgat 72240
gacggtgccc aacgataacc agtccgctcc aaggacggcg cgcacggcgg agacggcgga 72300
tgacggtgat gggtcgacac ccctcgccga cgactcacgt gctcctccag aggccgacgc 72360
gcggaccctc cgacgtcctg gcccgccgct gccgctgccg ccttcccttc tcccgccaga 72420
gccagcaact cctcctcctc ttcatcagcg tctccctcgc ttgcgcatcc gcatcgtccc 72480
atacaggcct cacaacgaca cagccgccac gaccccgccg ccatgggtgg cggcggcggc 72540
cgaggcccgg cagcggcgcc gccagcggcg accatggtgg gagagcaact cggatgacga 72600
ggaggaggag ggggagatgc ggtccgagag gaccgctttc ccgccgttcg cgtaagcgcg 72660
gccgacatgc gggcgcgcca cagggacgga ccgctgccgc tgtgactgct tacggtgacg 72720
tggttccgga ccgccaacga cgtcgacgcg gctttcttgg cgtacagctc gcgcagcaga 72780
ttctcgtact cgccctcgtt ttcgggtccg aaggcgatga gctcgatgtt gaagaccgac 72840
gccgaattgg atttgcgcac cacgcacttc gtcagcactc cgtaggccga gggcttgatc 72900
tcctcgatgt ccttgagcgt gacgatgagc gactcgttca ccttaagcac attgaactca 72960
cctacgtggc gcgccggcga aacgagcttg acgggcgctc gtacaaaaca gcagagggag 73020
acggcgcagc cagtgttttt aaagataaaa caaggcacgt ggtctgtgcg gctctcccag 73080
tagctgagta gatactcgac acaatagacc gtgtctgtct tgagcatggc gtcgcacacc 73140
gagtaattgg ggtttttaca gatgaggccg gcatcggtga cgcgcagctc gctgggaccc 73200
aacttgagga tacgccgcgt ggcctgcacc agatcctgat ggagaacctt gttcatctcc 73260
atcgcaccga cgccaccgcc gatttattta cccggcgccg actcgtcttt tccctccagg 73320
attccgttaa tgtccatgag cttgctgacg atcgccgtta atagttgcgt cttctcacgg 73380
aggatctctc cgtgactgca ggtcgcgcag tcgccgtgca cgtacttgag gaaggcggcg 73440
tacttctgac ccgcgttcac gaaatttaag cgcgcgtcca gagagggcag caacagatcg 73500
tagacgcgcg gcagcatcgg ctcgaactgt aatagcagat cgtcgtcaag atcgggtagc 73560
gcgtgtccgt cttcaccgtc ctcgtcgtca ccacctcccc cctcgagccc accgctcgta 73620
ccagccgcgg gctccgcgtc ctcgtcgatc accagcggtc gcgtcggcac cggagaatcc 73680
acgtcatcct gcacgtcgtt ttcctcctct ccgtcgtcat cgtccagaaa cggcacccgc 73740
tgcttagccc aggacattct tttttccgcg tcctcaatca gcggcgccga tcgccatgaa 73800
tccgagtacc cacgtgagca gtaacggccc aacgactccc cctcacgggc cccacaccac 73860
gtttcttccc ccgaccagcc cggccccgtc caccagctcc gtcgccgccg ctaccttgtg 73920
cagtccgcaa cgacaggccg tttcgcgtta cagcggctgg agcaccgagt acacccagtg 73980
gcactcggac ttgacaactg agctgctatg gcacgcgcac ccgcgtcaag tacctatgga 74040
cgaagcgctg gccgccgcgg cggccgcctc ataccaggta aatcctcaac accccgccaa 74100
ccgttaccgt cattacgaat tccagacgct cagcctcggc acctcggagg tagacgaact 74160
gctcaactgt tgtgcggaag aaaccacgtg cggcggcacg caatccaccg tactcaccaa 74220
tgcgaccaac accactagct gcggcggagc cgtcgccggc agtagcaacg taggacccgc 74280
cggcgcttcg gccgcctgcg acctagatgc agaactggcc ggcctcgaaa cctcggcggc 74340
cgactttgaa caactgcggc gactgtgcgc gccgctggcc atcgacacgc gctgtaacct 74400
atgcgccatc atcagcatct gcctcaaaca ggactgcgac cagagctggc tcctcgagta 74460
cagcttgctg tgcttcaaat gcagttacgc gccccgtgcg gcgctcagca cgctcatcat 74520
catgtccgag tttacgcatc tgctgcagca gcacttttcc gatctgcgca tcgacgacct 74580
gttccgacac cacgttctca cggtcttcga tttccacctg cactttttca tcaatcgttg 74640
ctttgaaaaa caagtgggcg acgcggttga taacgagaat gtcaccctga accatctggc 74700
cgtggtgcgg gccatggtca tgggtgaaga cacggtgcct tacaacaagc ctcggcgcca 74760
cccgcaacag aagcaaaaaa acaaccctta tcacgtcgaa gtgccgcaag aactgatcga 74820
caactttcta gaacacagct cacctagccg cgaccgcttc gtgcagctgc ttttctatat 74880
gtgggccggc accggcgtca tgagcaccac gccactcacg gaactcacgc acactaagtt 74940
cgcgcgacta gacgcgttat ccacggcctc ggaaagagaa gacgcaagga tgatgataga 75000
agaagaggag gatgaagaag gaggagaaaa aggaggagac gatccgggcc gtcacaacgg 75060
cggtggcacc agcggggggt tcagcgagag cacgctaaaa aaaaacgtgg gtcccattta 75120
cctatgtccc gtacccgctt tttttaccaa gaaccaaacc agtaccgtgt gtctgctgtg 75180
cgaactcatg gcctgctcct attacgataa cgtcgtcctg cgcgagctgt accgccgcgt 75240
cgtctcgtat tgtcagaaca atgtgaagat ggtggaccgc attcagctgg tattggccga 75300
tctgttgcgc gaatgcacgt cgccgctcgg cgcggcacac gaggacgtgg cgcgctgtgg 75360
actcgaagca cccacctcgc ccggaggcga ctcggactac cacggcctga gcggcgtcga 75420
cggcgcactg gcgcgacccg acccggtatt ttgccacgtc ctgcgtcagg caggcgtcac 75480
gggcatctac aagcactttt tctgcgaccc gcagtgcgcc ggcaacatcc gcgtcaccaa 75540
cgaggccgtg ctcttcggac gcctgcaccc ccaccacgtc caggaggtga aactggccat 75600
ctgtcacgac aattactata taagtcgact tccgcgacgt gtgtggctct gcatcacact 75660
cttcaaggcc tttcagatta caaaacgcac ctacaaaggc aaagtgcacc tggcggactt 75720
tatgcgcgat ttcacgcagc tgttggagag ttgcgacatc aagctggtgg accccacgta 75780
cgtgatagac aagtatgtct agcgtgagcg gcgtgcgcac gccgcgcgaa cgacgctcgg 75840
ccttgcgctc cctgctccgc aagcgccgcc aacgcgagct ggccagcaaa gtggcgtcga 75900
cggtgaacgg cgctacgtcg gccaacaacc acggcgaacc gccgtcgccg gccgacgcgc 75960
gcccgcgcct cacgctgcac gacctgcacg acatcttccg cgagcacccc gaactggagc 76020
tcaagtacct taacatgatg aagatggcca tcacgggcaa agagtccatc tgcttaccct 76080
tcaatttcca ctcgcaccgg cagcacacct gcctcgacat ctcgccgtac ggcaacgagc 76140
aggtctcgcg catcgcctgc acctcgtgcg aggacaaccg catcctgccc accgcctccg 76200
acgccatggt ggccttcatc aatcagacgt ccaacatcat gaaaaataga aacttttatt 76260
acgggttctg taagagcagc gagctactca agctctccac caaccagccg cccatcttcc 76320
aaatttatta cctgctgcac gccgccaacc acgacatcgt gccctttatg cacgccgagg 76380
acggccggtt gcacatgcac gtcatcttcg aaaaccccga cgtgcacatc ccctgcgact 76440
gcatcacgca gatgctcacg gcggcgcgcg aagactacag cgtcacgctc aacatcgtgc 76500
gcgaccacgt cgttatcagc gtgctgtgtc acgccgtctc ggccagcagc gtcaagatcg 76560
acgtgactat tttgcaacgc aagattgacg agatggacat tcccaacgac gtgagcgagt 76620
cctttgagcg ctacaaagag ctcattcagg agctgtgtca gtccagcggc aacaacctat 76680
acgaggaggc cacgtcgtcc tacgcgatac ggtctccctt aaccgcgtcg ccgttgcacg 76740
tagtttccac caacggctgc ggcccctcct cctcgtccca gtccacgccg cctcatctcc 76800
acccgccgtc gcaggcgacg cagccccacc actactctca ccaccagtct cagtctcagc 76860
agcatcatca ccgtccccag tcaccaccgc cgccgctgtt tctcaacagc attcgtgcgc 76920
cttgacactg tacggcagaa aagccggctc caagtgcaag cgccgcggca gcaccatgtg 76980
caaaaacttg tccttgcgcg cggtttcgcc gccgggaaag acgggcgaca gcacgttagt 77040
tacagccttg agaacctgct caaagtactt gtcggcgtga atgggcacgc cgtgctcgcg 77100
cacgtagctc ggatcttcgg ctacctcgta gttgcacacg gccgacggtg gtttccgcgc 77160
cctcttcttt gccggctctc ctcctctcct gttgctctcc tctaccccgc cgccgtcagc 77220
gtcgtcgtcc gtgccatcaa tcgcgtccga ccgggaaacc acgccggcgg ttacagaatc 77280
accgttgtcg gaggaaccct gcggcgccgt ccggacaccg ggcgccgtca gaacgtaaaa 77340
gacccgatcc ccgaccgagg gtagctcctc agaacgggcc gccaatcgct taatgacggc 77400
aatgtgcggc aggttagatt gacggtacag cgagatgtcc ttagagagca ccgacgaaag 77460
caccaggtcc tcgacacgca cacggtgcag gtacagatcg tcgcgggcct gcaccaagcg 77520
gcgtaagata cgccagaaac cgcgtggcac gccgtacttc ttgacttcat cgagtgagag 77580
gcgcgacagg cgcacggctg cttccgagac ctcgcgatcc tcaaagagca gcgagaggac 77640
gtcacgcgtg acgcccttga cgaactcgca ggccgtcttg cgcaccagat ccacgccctt 77700
catgctcaga cccgaggcgc cctccacttt gccgatgtaa cgtttcttgc agatcatcat 77760
aagagagacg aagacctttt caaactccag cttgacgggc tccacaaaaa gacaggccgt 77820
cacgtagtgc gccaggctgg gcccacgcgc caccagagcc tgcggcgtca ggccacgaaa 77880
gcggacaaac acgctgtccg tgtccccgta gatgacccgc gcctccaccc gccgttcgtt 77940
cgagccccct gacgatgttt cgagcccctc cggtaacgcg ctgctctcct ccgaatcccc 78000
ctcccgcgtt cccactacat agtcttcctg attaaaaaaa ttgtgcaaaa aacacggctc 78060
tgaaaagttg tctttgatga accgcgccgt gcgctctagc atgtcgcgac cgatgcgcgt 78120
gatgctggcg gcgatgggca gacacggcat cataccgttg accacgccgg taaaaccgta 78180
gaaagcgttg cacgttactt tgagcgccat ctgttccttg tcgagcagca tacggcgcac 78240
agggtcttga cactcgcgca tgcattcgcg cacggcacgc cgctgcgaaa cccacttgtt 78300
gagcagttcc gagagcaccg agacgcgcac cgaagcacgc acaaagcggt gggtcacgcc 78360
gttctctagc gtgacgctgt atacgtcggc ggggtccaca gggtactcgc cacccggcac 78420
cagcagggtg gagtagcaga ggttgtgggc catgatgatg gaagggtaga ggctggcaaa 78480
gtcgaacacg gccacggggt cgttgtagta acccacctcg ggctcaaaca ccgtggcgcc 78540
ctggtacgaa accgccgcag taccgccggc gccgtgattg tcgttggaaa cgccgacgcc 78600
gccactactg ccggagccga cgctgaaaac gccgacgctg ctactactgt tactgccgga 78660
gccgggtgaa acgccgtcct gactggacgg cgcagattgc aagggcggcg acatctgaaa 78720
catagccgcc acagaacccg cgtcgccggg cacagcggcg gtagagatga tagcagcgtt 78780
aggtgacaca gcaacgctat tcgtttcggg caccgtcgta cctttgctgt agtggttggg 78840
caggataaaa tcgcggcagg cgcactcgtc cagcagcgag gtgtagatac ggatctgctg 78900
tccgtcaaag atgacacgcc gcaacggaat tttagccagc cgcgcgatgg ccccggcctc 78960
gtagtgaaaa ttaatggtgt tgaacagatc gcgcaccaat acggcgtcct gcagacagta 79020
acggcctacc tgggcgcggc cctcggcatt agccacgaaa caacgcggga tgtccttgta 79080
agacaggtca tccttgcgtt gccgcaggta aagctcggcc atagtgttga gcttatagtt 79140
gggcgagtta gtcttggcca tgcatacagg gtacatgtcg ataaccaccg aacccgcaat 79200
atacaccttg gtggcggccg tgctggccgg attgttgtga gaagccgagg gaaaagcggc 79260
ggcgtactgc cgcttaaaac ccacggcggg gctgtgtaaa aagaaacggc cgccctgcgc 79320
cgtaggcaac ttgcagaagc gctgcgagtc caccttatac aggtactcga gacgcgtgag 79380
gatgtacttc aagtcaaaag agttgatgtt gtaaccggtc acaaaggccg gcgcgtaccg 79440
ttgaaagaaa agcataaagc ccagcagcag ctcgtattcg gaagggaact cgtagacgtc 79500
cacgtctggg cccacctgcc cgcaggtgcc gatcgtaaag agatgaagac ccgagtgccc 79560
aaagatcaca ccctccgaag tgcagccccg accatcgttc ccgtttggga tcccctgatc 79620
cacggcggtg tttccccccg tctcgtagca cacgcacgag atctgaatga caatgtcatc 79680
ggacttctcg gcgcagggaa aaccaccctc gccgctcatg cactcgatat cgaaggacag 79740
gcatcgatag cgcggccacg agctgtcgtc gggcacagcc accaggtcag agacatcgca 79800
gtctacctcg atatcacaag tcgacgcgcg accctgctgc cgccagtcgt aacgattcac 79860
ggagcaccag ccgaacgtgg tgatccgccg atcgatgacc aaacgcgtca gcggatccac 79920
acggacctcg tacacgggaa aaccctgctc cagcagatac tcgccgattt ttctggccat 79980
ggtccagttg ctgatagaca cacactgcaa atcgggcacg ggtcgcgtcc cgtacccata 80040
gatggaggtc ttggtggccg gcgtgacaga cacggcgtat ggcgtccgcg gttcgggcac 80100
tagttcgccc acgctggcaa tgacctcacg cagcctatcg gtgtcgctgt actcacagta 80160
aaagtagctg cgctgcccga aaacgttgac gcagatactg tagccgtgtt ctgtggcccc 80220
gaagaaacgc aacacgttcc ccgaaggcac cagatgctga cgatagcgcg gcgacacgtt 80280
ttcgggcgag tcgaagaaga gcacggcgtc cgtctgatcg taggtgtgaa aacgaatagg 80340
tcccaccacg cgacccacca gggtctcgcg ccaaggacac ggccaaacca tgtcatgact 80400
caacaaatgt ttaatctctc gatagaacat gagaggcagc cgtcccgtct tatgcttgat 80460
caaccccgtc tgaccgtcga acatgacacc tcgcggcacg atctgcaaaa actgtttctg 80520
tggcggccgc ttgcccgagc cctgcgcgga gccgggctgc gaacgctgac gccggccacc 80580
cgcgaccgca ccgccggtca cgccgccgct cagatacggg ttgaaaaaca tagcggaccg 80640
tgagaggctg acagcttacg aagcaaaatc acaaagaaaa tacacatgca gcacctagat 80700
atccagttta accccgtata tcacaagtct ctgtgtcaat attttttgtc tagttttttt 80760
ttcctcctgg ttcagacgtt ctcttcttcg tcggagtctt tcaagtgtct gtagccgttt 80820
ttgcgatgtc gcagccggtc tagcaggtta ggcttctgtc ccttgtcctg cgtgccagtc 80880
tgtccgtcca aagaatctgt accgttctgc tgcgctcgct gctctgcgtc cagacgggcc 80940
agggccagaa gcatctggta agcctgctcg ttggtgtaag gcggagccgc cgtggatgca 81000
tcagacgacg gtggtcccgg tcctttgcga ccagaattat aaacactttc ctcgtaggaa 81060
ggcggagcct gtaacgacgt gtctttggtg ctgcccgacg tcacggtggt cccgtcggcg 81120
gacaccagat agggaaagag gttctgcagc ggctgcgtgc acagacgccg ctgtcgagta 81180
tagatcaaat aagtgataat gactacggct atggccacga ggatgatggt gaaggctccg 81240
aaggggtttt tgaggaaggt ggcaacgcct tcgaccacgg aggccaccgc gccacccacg 81300
gccccaatgg ctacgccaac ggcctttccc gcggcgccca ggccgctcat gaggtcgtcc 81360
agacccttga ggtagggcgg tagcgggtcg actaccttgt cctccacgta ctttacccgc 81420
tgcttgtacg agttgaattc gcgcatgatc tcttcgaggt caaaaacgtt gctggaacgc 81480
agctctttct gcgagtaaag ttccagtacc ctgaagtcgg tattttccag cgggtcgata 81540
tccagggcga tcatgctgtc gacggtggag atactgctga ggtcaatcat gcgtttgaag 81600
aggtagtcca cgtactcgta ggccgagttc ccggcgatga agatcttgag gctgggaagc 81660
tgacattcct cagtgcggtg gttgcccaac aggatttcgt tgtcctcgcc cagttgaccg 81720
tactgcacgt acgagctgtt ggcgaaatta aagatgacca cgggtcgtga gtagcagcgt 81780
cctggcgatt ccttcacgtt catatcacgc agcaccttga cgctggtttg gttgatggtc 81840
acgcagctgg ccaggcccaa gacatcaccc atgaaacgcg cggcaatcgg tttgttgtaa 81900
atggccgaga gaatggctga cgggttgatc ttgctgagtt ccttgaagac ctctagggtg 81960
cgccgttgat ccacacacca ggcttctgcg atttgcgcca gcgcccggtt gatgtaaccg 82020
cgcaacgtgt cataggtgaa ctgcagctgg gcgtagacca gattgtgcac cgattccatg 82080
ctggacaaat gagttgtatt attgtcactc gtacttcttc tggtcctatg agtgatattc 82140
agactggatc gattggccaa acgttccaat tccaccaaag atttttgctt gatgccttgc 82200
cagaacacca ccagaccgcc gctggtttcg aagacggaca cgtttccgta tttttcatat 82260
gtttgattgt atgaagtatt gaaaatctgc tgtaacttat ttatagcctc atcacgtacg 82320
cagtccagcg cggagtcgga catgttcact tcttgtttct tagacagaaa agttgcagtc 82380
attttggcag aagaaaagtg gtacgagtct tcggcttcgg aacggatagt acgttccgag 82440
gcttcccaga aggtgagctg gcaggtgaca ttcttctcgt cctgtatatc ccaagagatc 82500
accgagtcgg cacgttcgag aaaagccacc aacctatggg tttctggcgc agcgttgggt 82560
cttccaaagt cggaaacgat ggtgtagttc gggaaaatga aaaacttgtc ggcgttttct 82620
ccaaagtagc tggcattgcg attggttccg ttgtagaaag gagaaatgta aaccacatca 82680
cccgtggaag ttgcaaaaaa atgataagga tacttggagc gcgcagtagt gatggtcagc 82740
atacagttca gattacaggt ctcacgatag agccaggtgc tgccgcggct gtgccactga 82800
tccttgaccg tcacgtaacg ggtactgtgg gtgttggaat aatcgtcggg aattaattgc 82860
atggttttgt tttcataact gtccctatga tatgccacga aaaccgtgcc tcctataacg 82920
cggctgtagg aactgtagca ttgagcaaac ttgttgatgt gatgaatctc ccacatagga 82980
ggcgccacgt attccgtatt gctgcccagc agataagtgg tgtagatgta agcgtagcta 83040
cgacgaaacg tcaaaacctt ttggtagacc cgtaccttaa aggtgtgcgc cacgatgttg 83100
cgcttgtaga ccaccatgat gccctcatcc aagtcttcat tgataggctt catcgaggtg 83160
cagatgatat tacgttcaaa gcgaataaga tccgtaccct gggccataga acacacgcga 83220
taggggtact tggtagtgtt gactcccacc acatctccgt acttgagggt agtgttgtag 83280
atagtctcgt tggctctatg actgacggct tcagaagacg ttacgtgttg agaatagact 83340
gaccgggttt gagcagacgt cgtacgagaa gtatggcttc cattgtgagt agaagaagtt 83400
gcatgggaag tactagaaga ggaaaccgca gcacccagac agacgataca caggttaacg 83460
cagactacca ggcaccagat cctggattcc atgttcgtcg cgggccaaat ccagcagcga 83520
tgaggcgcgt cgtggtctct tgcgtgtcgc gcggaccctc cgggaaacac ccgcagtcga 83580
ggaggaggga tacggacttg gcagccaagg tcggtccggc tccctgaaga cacccgagac 83640
ggccgcggcg gccgtcaggg tggagggctt ggccacggga gctgttggca cgtcgccact 83700
ctcatccggt ctggacagat gcctgtagag gaggagatat agatctttgg acttataaag 83760
acttccttcg tgacgaagca gcagcggcca ctctttgtta tacgtgagaa tcacatctct 83820
gtccgggtgc agttcgtcgc gcaggcacgc gatcgagagt tgtttcccga aagtttcatt 83880
atatagtgcg acggagagca cgagctcccg cacgtgcatc cacatctcct tctgcagcac 83940
gtttaggtcc tgacagtccg aaaaattgaa aaaacccata tacttcacca ccatccactc 84000
actgggatac acggtacctt ccgcgcattt gaccaaatcg tccttgacgt ggggtagtac 84060
gcccgcgttg tcgcaggcat aggccatgtc cacattgtga gagaggggat aacgatcggt 84120
gcagtgggtg aagaggggcc cgttacacaa ctcgtagatc tgctgaccca gtagcgggag 84180
ggattccaca ggcagactct tgtggatcag gttattgacc acatacaggt gctcatcgta 84240
ggtgaactga tcacccacgt ccaccacgtc ttggtcctgg tggtattggc tgcggtacag 84300
aaacccattc atgagcttag agataaagtc cagacacaag ggccccacta gattgacatc 84360
gatgagcttg ctagtcagac gctcctgcgt tttgatgcaa cggatcacct tgccatagcc 84420
cacctccgag accttctgca ggtaggcgcg tttgcgcacg ttcacctcgc gagtgacgtt 84480
gtggatgcgg gagcgcgcgt ccaccaagtc gagagcctcg tgttcgtcgc agttgcgcac 84540
ccgtaagccg ttctcgctgc cgtcgccgtc ctgcccattc acccctcccc ctaccacttt 84600
cttgcctcct ccacgagccc ggccgccgcc accgttattc ctctgactgt gagtactgct 84660
gttgctgctg ttgctggccg tcatcaaagt cgtacccgtc cccgacatcg cctcccgtcc 84720
acgcaggtga atagcctcgc cctcggggcc gtcgcccccc gtgccatctg gcagcggacg 84780
tcgaatctcc tcgagaatat gcttgatttt ggtgtacatc tcgttgcttt cgtggagctt 84840
gttgaacacc gggttgtcct cgaaagcttg aatgctgagg gatgtgatga ggtcgatgat 84900
cctgttgggg gcggcaaaga ccgaccccac gaacatgcgc tcctccccgt ccaacgcctt 84960
ttccccgagc acgaagatgt cctccacgtc ctccccgtac agatggcgac tgatgccgtt 85020
catgagcgcc cggcacagct ggtgatacac atttagctgc tggatggtga tgcccacccg 85080
cttgacgata acctccgagg tacgggacca gtaggtaaaa tccgacaagg aatatattcg 85140
ttccggtata tccgtaaaca ggttgtactc cctcagcgcc tcctccgcct cctggatgta 85200
gctgtggtag gccgatgaag aagagaatag gcttttgagg gccgaaagga ctccagccaa 85260
gtgggggatg cgcgttgtca ggtccagcag gtcctgctcc accgtctgga tattcacatc 85320
ggactggctt gacggacggt ggaccgctat atggttgcac agcaagccct gcagccgctt 85380
gttcagcgag cggccctgat tcgggatgat ggtcagctcc tcgtagcatt gggcgcatgt 85440
cgtcccttcg acgtacactt cctgacgcgc caccggcgag atgccgcata ggcgacggag 85500
gagctccagc aactgcgcgc agacctccag gccggcctcc ggcgccagga tcccgtacac 85560
gtagttcatt ttgcacagga agcgctcgat gtcgttgagt gtggccagac tgacgctgaa 85620
acggacgttg tccgtaaact ggagctccac ggtgtgatgg cgatcgcagc gatccaaacg 85680
gaggacggta cggtagaagg ccgcccggtc cggctggcgc gagtaggcca tcagcgcccg 85740
atccagcaaa gccgtatcct cgtgcagcgc cttcagcagc atctccaggt agagcgtcag 85800
caacgaactc tgcgtacgat tctgcgccac cacctccggg tagatcttcc ggtacagata 85860
cactatagcc gccgcgtttc tcttgaacgg cgtggactcc gccagtaaca cgttcggatc 85920
gcagtacttt agacactcca gctccatggc gtattcgttg catttcgaac acactacgca 85980
tagtttctgt aacaaattca tctccatgac tcgactcgct cacgtacgag acgctgtcgt 86040
ccggtctggc gccggccaga gacatggagt cggtgcacaa ataactcgcg ggccgctcgc 86100
tatgccgact gacgttgacg ttaatatata acgacgtcgt cgacgacgcg ggttctgctc 86160
ccgaagctgt tgccgccgct tgcggcgcaa cctcctccac caccgccgcc gccggctcct 86220
ccgcctcggg cgacgggggc tcggagatga ccggctgtgt ctgacactcc tccccttcct 86280
caggcggccc gggcgccgac gcgaatgtcg gagtttgcca gcgcggcggc ggtctctgtc 86340
tctggtgccg cggcgctaac cttcggggct gttgctgctg ttgatgatgc gacgccgtct 86400
gtcgccgctg ttgcggcggt agctgatacg gtgtcgcctg gtgctgctgt gtcggtggct 86460
gctgttgctg ctgttgttgc ggtctgaaaa gcggccacgg gggctgcgac tgttgttgct 86520
gttgttgcga tgctcgtggc tgcggcggcc gttgtcgcgg cgtttgctgg cggttacaac 86580
cggctgcgtt tggccggcaa taacccgctg cccccgccgc ccccgctgct cccgccgacg 86640
ccgccagcct cgtcttcgcc ggcgttcacg agaaagcagc cacctcccgt ctcgccgggc 86700
acgccgaagc aaatggagtt gcccgcgacg gactcgccga gaagaagacc gccacccccg 86760
acgccggacg ccgcgccgac gccactgggc gcgaagagcg ccgacaggtc gtgcacctcc 86820
cccccggcgg cgtccgttaa tcgctgggcg tcggcgtcca gcacgcgtcg caagttctcc 86880
agcgaaaagt cctccacgcc ctgctcctgc aacgcggcaa acttgtccat cagcgacgcg 86940
gccagcgcct cgcagccatc cacgaagaag agcacatcgt cggacgcggg gatctcctcg 87000
cgcacgctca gaatctcgta cacggccatc acttcggggt cgcaatccaa gttctcggcg 87060
tccagcgcca gcatgacgcg gttttttata agatccgcgt caaaaagcac gttctcgcgg 87120
cgcgagcgtt tgatgagcac gtcggccaga cgcgtagcca agaggtagcg ctggcgcatg 87180
aaacgataat cttggccgct catagagctc acgttaaggc tgcgttccac accgttgccc 87240
gaaaagtagc cgatctgccc aaactgatag atctccttgc tgttgttgat acccgcatat 87300
ttttccacgc tcacgggcac ggtcaccaag gaacgatgct caaaaacgct ccgtaccaac 87360
gattcacgcg ccacagtggc ggccatgggc gccggcacgc ctgcggtctt caagcccttg 87420
acatgcaacg caaattcggc gggcgacgag aaccgcggac tagcacctaa cacgtgagga 87480
aactgcgcgt ggttctgcgt cgttaagcgc gtcgtcaacc cgtgcagcga gccgatgtag 87540
tctttgaagc cataatagca gaggaatttg ttatggaaac ggctttccac gtaactcagc 87600
acacagtctg gcgccacatc cagcagatcg tgctcctgat agtcagccgt cacagccacc 87660
agaaatttga cgaaagcatt gaactcgccc atgtcaccta tgggcacatt cttgggcaac 87720
gcgttggaac agaccttctg ccaaaactgt aagcagggga gaccacattc aggaaagagt 87780
cgctcgtgat gtcgatacag cagaaatccc aagcagccct tagccggatt acgacgcgga 87840
acgtgatcgc ggcgaaaaaa cacgctaccc gcgttgccct tgcccgcgcg gtagatgggt 87900
cggtttttca cccgcaccat gatcaacgtg ggtaccgaca gccgcgagag cttgatctcc 87960
atgggcacca cggcgtacgt gccctgcgcg tacagcctaa agtccagcag gcggtcgtga 88020
tccgaattct tggacgactt gatctgcttg gtgaagagaa agcccttgcg cgacgacgtg 88080
gtggagaacg cgccgtgaat ggattgaaaa tgctgcgtca tccatttgga taccaagttg 88140
gtggtcaacg gattgtccac aatgtatgag gtagcggtaa taagcgccac gttctggatc 88200
acgtaaaaga cggatctgaa ataggcgtag gctagcagcg gctggaaggc cacggcgtag 88260
ggattcagat ccaggttgaa ggcctgcgtg gcgcccgcca cctcgtcgcg gctgctcttg 88320
aggcgcacct ccgaaacgaa acccagggcc tcgtcgtcca caaacttgtt gagcgccgaa 88380
aagacggcca caaagtcgct tttgccgtgc gcgctaaagg tatcctcgcc cgtcacgggg 88440
tcgatgagcc gcatcttgcg gcagtaatcc aagatgcgat tgagccgata ggtacggtcc 88500
acgctagcgc ccaacatgcg accgccgcgc cccatcattc ccccggaatc cccaccaccc 88560
ccaccaccac gaccgccacc cagaccgtcg ctcgggcccc cgctcacgtc tcgtccacca 88620
cccccgccag caccgccgcc cggaaccccg tcgtcacctt tgccgtccaa acccccgtcc 88680
ttggcgtcga cgttgtaacg ccgaccgaag ctgcccaaaa tatccacgtc gttgagaaaa 88740
cgcgactgca cggtgatcac gcagggctcc ttcttgggct gcttgggcac cacgggcaag 88800
cgggtgcgca cccgcacgaa ggccgtctga taacacgtgt ggcaacaagt acccccacag 88860
gcctcgcaca gccccgcggc gcagcccacc aggtgattcg tgagcgtcga cgaacccgac 88920
aagcccgtgt tgtacaccga gacacgattc agataccaga cgaagcccga aactagctgc 88980
ggacacgtgc cacacaccaa cgccaaatgc tgcggcccat agcgttcgtc cttgagcggc 89040
gcgccctgaa acttgagcac cttgcgcgcg tcgttgtaga cgtcttcgca ggccgccgac 89100
aacccgttgg tgaactgaat agccttgagc aacgtctcct gactggccgt accgccggcg 89160
ctgggatgcc gcgccgacga ctggagatac accagcctgt gctggtagag caccgaatta 89220
gcgctgaaga ccaaggcggc cacgtgcgtc gagagatgca acttgagctc ggtcagcgcg 89280
cggatcagat cgcggtgatc ggttgcgttg gtcactaaag gccactcgga aaagagcata 89340
gattcggcag gttggtaagc cgaatcgaaa aataccgagg caaaactgaa ggccaactcg 89400
caaaccaccg cgtcactcag catcagatga tccttttcca gactgctgag tcgctggctc 89460
atgtacccca agtagcgctt atgtggcgcc agcttcaccg actgctgact gtcgtgcaca 89520
aactgccgca acgccgcctc gatcagcaca cgcggctccg agaagcgcag cgattgacac 89580
catgacgtgt acacgtagta gaaaagcgtc tcgcttacgg ccggcacgta gagccctcgc 89640
gcctccacaa aagcgctgcg cgcatccagc gagacctcgt cggcttcggc gtcaagctgc 89700
aacgaattaa agagcgtagg cgggtacaac ggcacgcgca ccgcctcgcc gccgtgcagt 89760
cgcaccgtgg tcgcctcctc cacgcatgga atcagctgac cggcaaagag aaactccttc 89820
aagccgttgc ccaccaccac gtgcacagtc gtctcggacg cctgacagcc caccgccgcg 89880
cacaacgccg ccagatcggt aggcacgcga tccgcctcgg gcatgtaagc ctccaacgcg 89940
tacttctggc gggcgtcctc gcacagccga tgcacgtctc cgtgatcctc ggtaaaagcc 90000
acgatgcctt gcgtatgatg aaagtagagc gcaaaaggac agaaggacgt gactttcgtg 90060
agcaccccgc cgtcgtaaca aagcacaggc gtgcgcacag agacgccgaa atccgcctcc 90120
accgtgagcc ccgccaacaa aggagcgatc accacgctcg aggaacggtc gcatagcgag 90180
agagtggcca gaatctcctg cgtttctgcg ttcaacctgc tgaagtagag aaaagccgcg 90240
ggccccaccg gcgctagcgc ggttagttcc tcgtggctca tggtggatga acggaagaca 90300
atggctacgc cgccactgag tgaattttat accaaggaaa agttcagcac gtcatgtttg 90360
acgcacgacg tctgagacac caccgtggcc accactgcgg tctggctgcg gttgcggacc 90420
accaaaggcg acaaccgcaa cgatcccagc aattcgtaag aaaagctaac cgctacggtc 90480
aggtagcctc tcgcagccag accgctagcc gacgcacccg cccgcgaaaa tagcgtgatg 90540
ttcgggacgg ctttgcgtca ccgccaacta acgtcggtag tcgagcacgt cgtttatcct 90600
cagcacaccg tccgatcaca atccgttttc ccactcagtc gcacaagcag cacataaaaa 90660
ccccacacag ggcacgtgaa aacaccgtcc ctagaaaacg gcgttttctg tcctaccgtc 90720
acccgtatac acaggcaaat cccaatcccg atccccgaaa acaccgtacg gtgtttgtga 90780
cctccaaaat cacatcagct aacaaaccgt gaaaagtcac gtttcacgaa cacggtgttt 90840
ttaaatcaca aagaaccgcc tgacggttta caagcagaaa caccgcacca cggtggtaca 90900
agcgcgatga atctggtctc gcaacctcaa tcgccgctat caccaccgat tttcgctgcg 90960
ctccgccgac aaaacgccgt acaagctaca caccccaaaa acccgcgcgc ctacgggcgc 91020
caaacctgtg tgttatctca acgtcacaac acgacacaaa ccgcgtaacg tggtttcccg 91080
aacacgtacg cggcacagac ccccgacacg tactcgaaga ccttacagtt tacgagtcaa 91140
taaaacagga aaagatccga actttaaaat tgtgtgtttt tattttccca tccccctctt 91200
tttaccaaaa aacacatttt tcgtcttgta aaaagtaact ttcgcccatt gccatgaaac 91260
accgtgatgg ggaacggtgt tgtgtgtcga ctgacgtcac tacggcgatc agtatcgacg 91320
tcgtgtatac ataacggtgc ccggtgtttt tattcggggc gttgtcgcgt cttgatgtaa 91380
tgtaacctga aaccgccgtg cccaagaatg cggaagccag cgtgtaatca taacggggtt 91440
ttgggtacaa tctgacgaca tctggcggcg agcgtacacc atcgaatgtg gcgatcgccg 91500
gctctacgtc acaatgacgc aaaaacacac tgtaaaaccc gcgtagacag ctttcctggt 91560
caacgagcgc catctggtgt cggcataaga acaggcatca accccgtggc cggcgaggcg 91620
gtgagcactt ttgttggtca cgtgaccatc agcgcaggaa gcgaggcccg tagaaccgcc 91680
caagaggcgg tgccagatgc caacgtcata atcacaaggt gatttgttac gtcacgcgcg 91740
cgcacgcacg cgcgcggtag aatacagcga tccctagtga agccacaccc attacgtgta 91800
gccatatccg cttacgtata cagccacacc cctaggtacg ccaccttatc taccaatcac 91860
agaaacggat atacaatgac ccctccctag actccacccc ttgtacggaa atttcagata 91920
ggtggaaccc gttagggttc caccgtcctc ggtgtacgta caggcttctc cgtctaccgg 91980
aaatatacac ctgctgacgt agacgctact cccggatacg cgtcataagc tactggaccc 92040
taggggggag tgtctacagg gctacgtgca cgccccctta cctagggtat ccgccccctt 92100
cctctgtttt ggcctagtaa acttaacgcc gccgcttctc acgtgacccc tgacaagcct 92160
acgtcacact cgcgtgacca cacccactcc ggatatacgt catcctgtgg aattccggac 92220
atacggtgac gtagcgagcg tagcgagcta cgtcacgtat gcgtgcgtca tctccggcgg 92280
aaatcatctc tgatgacgta gcgagcgaag cgagctacgt catcagtccg ttttacgtat 92340
accggatgct aggcgacgcc ccgtaggggc ggagcctagc ttccacccct aggatgcata 92400
ccctatatag cataattctt ctaacgaaac gttctacgaa aacggactgg cggaacggga 92460
accaccgtaa cccccccccc tcaccccccc ccttctcctc cggaaccggg gggggcaaat 92520
ttttaccaaa tttgggcaac catgatttcc aatgggacgg cgtttccgtg cgcatgcgca 92580
gtcggggcga gtttttggtt gtcagggcgt tgccacgcgg attatgggat ggtgactcga 92640
gtgcgcatgc gccggggatg ccgcatggaa aacctatata taaggagggg tgaaccaggg 92700
gccccggggc gcatgcgcgg gccagggccc gcgggagggt cgccctgcgc atgcgccggt 92760
aaaattccac tgtgtgtgtc gtgcgcatgc gccagtattt ttccactaga ggcggtcagt 92820
gcgcatgcgt cggtaaaatt ccactagatg tgcgccgtgc gcatgcgccg gtatttttcc 92880
actgggcggc cgcacctagg gagcgcgagc cccgtgccgg gcatgggccg cggcggtgga 92940
aaattaccgc tccgcccacc taggcggggc atctgaaaac ctataaaacc cggcgtgccc 93000
gccgcccccc ggcgcagtcc gcggcagggt tccggccgtg ctgcggtccg cacgctgcgc 93060
ccgctcccgc ctgcctcccg ccctaccccc caccctcccc ggccgaggcc cggcgccggt 93120
ccgtccgcgg gcccgtccca ccgccctgga gcaccatccg gggccgtggg ccgggcaccg 93180
ggcgcggccc gctccggacc tcggccgggg gtccctcccc tccccccgct cgaccccccc 93240
atccgacggc ccggccgggc tgggaccccc gcaccggggt cccggttccc gtccgtggcc 93300
cggggggacc cgagcggggg cttcccaccc ccaccccgct cctccccggg ctccggcccg 93360
ggatccctcg ctgctcccgg cgacctccgc cggcttcccg gtccacccgc cgcggaatgg 93420
acgggacccg gggtccgcgc ccttcccctc cccccacggg gggctgggtc gcggaccccg 93480
gttcctaggc tcgttccgcg gtgggcgacc ggggatcccc cacccagctc cccttcccgg 93540
cccgccttgc tggcttttgg gcccctgcgg gctttttttt tccggctggg ggtcgcggcg 93600
gtcggccgac gacgacggta ggtgggccgg gtggacggtg gtggggacgg gcgacgcccc 93660
ggctcgacgg caatcggtcc cggaaggttg ggggctgggg gcccggtcag gagctccggg 93720
agcggggtcg accgcgacgg cttccgggtc tcgcggcggc tccctctcgg cggctccggt 93780
tgggctcccc tcccccctct cgagggtccg gccgccagtc gtgaccgggg gtccctcggc 93840
ctagccgccg gctctcggtc cgccttatcc tgggcgttgg cctgtcccgt gacgctcccc 93900
tcccccgctg ctccccaaaa aaactccgcc cgaaccgtcg cggcttgctg gccctgggcg 93960
tggtccccca ctcccctccc cccatcggcc gcccagccgg ggtcggcgcc tcggacccca 94020
ccaggctgtg gcgtgtgtgc tggccgatgc ggcggcgagg ttgggtgtgg ccggaagcgc 94080
tcggggtcga cggtgggccg ccatgacacc tcaattgtcg tcagtacgcc cctccacaat 94140
caccgtcccc acacgatggg cccggcaggt cacccaacgt tggttcaggc ccagtcgggt 94200
tttttccccg gcacgaacgc acgtccccgt gggctccacg cgttttccac cctttcctgg 94260
aggggtccgg aacaccgtga atccacgggg agggtcccgg cacgggccga ggagaccacg 94320
accgtcccac ccggcgtgtc gactcgtccg agacccggga agggaacagg ccccaccttt 94380
ttttcccttc tccgattttg ccgtggaaaa cccgtgaacc gatacgggtg cagacggccg 94440
aaaaaaatcg agacgacaat atgacggcag ggcgcgatct tctcccccat ccgacaaaac 94500
cgtgtccctt aaaattcccc acctttctct gttcaaatgg ccccgaaact gtaaaacacc 94560
gtttgaccgc accccaaccg gcgccatctt ggtgaccttc tcgacggttc tctcgctcgt 94620
catgccgttc tgagctccga catggcggac gagagaaaat ggcgtcgaga gcctaggagc 94680
gtttttgctc caggcgggta aaaaaatagc acgataactt ttctgtgctt ttttttgaga 94740
cgttttagaa gagctttttt ctgctcagag cgaaaaaatg atagccctga aaatctcgac 94800
gagtctggcc gagcggcgcc atcttggagg aggggcgagt cgcgggcacc gcctcggtac 94860
cccctggccg aggcgagtcc gcggtcgccg cctgttccgt gatgctacct agagggcgct 94920
gtcgaggcga ctcttcctgt tttcgccctg agggctaacg gtcgctgacg tcaaaccatc 94980
tcgtgctcgc tgagtcacat ccggttgttg acaagcgatg gaggaccgca cccaaagtgc 95040
gccctctagt catcgcgcct gacccctttt ataaactgct cgaagaaaag aacaccttat 95100
gtgaaaaaat acagaatgat gacaagttca tccaacacaa ccgctcaaca acgccatatc 95160
tatcagtgtc caaaaactat cttctatcct ttgaaactat aaatgctgcc tatatacata 95220
tttagtatcc aagactctta ccacgtagac gaaaagaagt gatacaatga tcttgacgtg 95280
tatcgtctat atcgtgctag atatattcag ataagacgcg caaaccatag atttctcatc 95340
agtatcatga aagacctata gctctatata cgaacctagt cattttagga cagccgccgg 95400
agaagccgac gagggatcgg gcgggtgcag ccagaacctc acgcccgatc ccgcctccgg 95460
taggcgattt gcatctgttt ggtaaaaagc tcataagtct gtatgtgacc tatatatatt 95520
atacgctatg tacaccgaac tgtcgctgtt gtataagaag aaaaaactct ccatatttat 95580
atcgtctgaa tttttgcttg atagacacgt gtttggaact ctgtcccccc acgttttcac 95640
tgtgtataac aaaaatatgt gtttctcaaa agatcttgag gtgtttgaaa acgggggaaa 95700
cctgcgtttg ggtgctctaa gccccggact gggacgtagc cggcgtccgg cacctatatt 95760
tttctatttt tttttacaaa atatatgatg aaccaagaat aaaactctag ctctcgtcta 95820
tttttaatat gctctactta gaaccttttt aatgacagaa tgaactccat gttatacgct 95880
ctttatatag tttctctgca ctaaccttta aaaccgtatc cttccctgtt gtacaaatca 95940
tcttttgata cacaatgatg acctgatatc cctccatata tatgatcgga tattattccg 96000
ttagacttgt cctccttttt tttcctcatc tcctgtatct ggagatatat gttgaccacc 96060
accgccatga ccaccaaaaa gctagccgtc acgactagaa atgtgtagga ttcggacttt 96120
ccgttcgaga agaaaaagag accgcgtctc tggacgctct ttttgtcagt ctgaatcgac 96180
ccgggatacg taagagagcg gccctacatc ggggggcgct cgagaccgac gacgttccat 96240
ctgaccagaa aaaaaaaggc acccctcggt ggcgacctct caccatcgtt tgcccgtccg 96300
cccgtccttc gtagccatca tcatctcagg ctctatcggt accatcgttg tcatctgaaa 96360
aaaaaactgc ctcacccacc tgcgtaaaaa caccatcttt ccggaggtgc ggtaagacgg 96420
gcaaatacgg tcgtgccgag gcaaaaaaaa cgcaccatcg acaccacacc ctcatgagca 96480
ccacctgtcg gtgttggtcg tcctccatcg ttctctacga acatctcgac gcccgggtga 96540
cggacgacgg caagacgtcc cggagaagac ggtgttctct cgggcggtac gctctctgga 96600
tctataatat ctatagtagc taaacgagac tgtgagtacg acgaaccaca tcatcttttt 96660
tttatgttgc ttctttagaa aatgacttat gtcgacgaca ctcggcatca gccatctcgt 96720
gaaacacgct cgcttttcgt ctctccaagg aacactgggt ccgctgaaag ggaccgtgta 96780
ccgaccaaag caaaaaacac acacgtagta acatgatcaa ccacgtctga atgacacgaa 96840
aacacaatcg tataacgctc tattcatgga acgaacttgg aataaaaaaa ccatcgcagg 96900
ccagaggcta agccgaaacc gtccggggaa gcgggcgcga gttttccgac ttagcctttg 96960
gtgctcgttg agcctctttt ttttttctga ttctctgaag aatcaccgtc acagccctat 97020
gacgcgaaat caattgctag aacataaacg ttctcaacag gtatgaaatg aacaaactag 97080
atgatgctat aaccttatat tgtgtgtata tagataggtg tgaaatttgt aggataaaaa 97140
gtgtcgttgt atgatgcaca acgatcgtga aactggagac tgtagctctc taccgaatgc 97200
aaatacacaa atgacatcga ttcccgtccc cacataaaga aatgtgcttt actgtgaaag 97260
aatgaagaag attcttgttc ctcgtacgac ggggccctcg ctcgtcgtgc ctcttccccc 97320
ctccgggaga ggggacgtcg gggccctccg tcgcaccggg ccgaagccag tgaaatgttt 97380
actacactgt catcagaata tatgatgtat attatttcct ccaaactcct caccatagcc 97440
accaattcgc atcacttaag aaagtagtag caaccgcggc ggcggcgacc ggccggtcgt 97500
cgtctcctcg tcctcaaatg ttgtacatgt gcagaaaaat gtgtaaatac gtgttattta 97560
tcccatgcgt cttgtacata gatatatgtt tttatatacg ctatttatac tttatatatc 97620
cttttgcata accatagaca gtcaaggatt ttaatgattt gctcatccgc ctttgagcca 97680
tcgcttagga gttagttcct ctatgttctc ggcccacctt ttcgactaca gtagcaaacc 97740
cttgtactac caccccgata aaaaccacat catcatcgtc accacgacct ggaaacgaca 97800
cacgttcccc cccaatcttg ggcatgtgta tatataaaaa gaatgggagg gagaggacgt 97860
ggggctcgag aagaaataaa cgccaagctc gattcgaacc aaaaaaccac atgtgtattg 97920
tgctttgttt ttttttttac ggtgggggaa aaggaggggg ccgtcattaa cggaaaccgt 97980
gtatggggtc cggacacgaa cagtacacag cttatgggga aaaaagctca cagagagaaa 98040
aaacaccaag ctcaggcacg cgtacatcat tattatcatc atcggatatc tcaccacggg 98100
tcatagtagt accaaggagt gtgtaacacc attttttctt ttctttgtaa cgggataagg 98160
gacagcaatc atcacgcaca acacccttca ctctcttttt agtcatccat atcatcgctg 98220
taacacagca tgtcctcgta atcgggcgtc tggcagcgca ttaccaccga gtcgtcttct 98280
tgcggtaccg gtggtggtgg tggtggcggc ggcggctgct gctgctgggt tgccgtcgta 98340
ctgtgattac cgttggcgga ctgcaccggg atgatgggct gcttgtgggg aacctggggt 98400
ggactgccgc cgtgagaagg cgacggcgtc atcaagttaa gctcaccacg gtgactccgg 98460
acaccggcga ggggcgccgg gggactggga gggaccgcgg tcgtcttgta gacgacggtg 98520
tccccgtgtc gatccgtggc tcgtaccaga tcttgactgc tagcgtcgtc actgtcttcg 98580
tcctcttcca gctcgccctc agagtagtgc tgctgtggtt gcgacggtgg ctgggcggga 98640
ggagcggcgg cgatcattgg agagggatgt cgatgactcc cttctctgtc ctttttatcg 98700
taggctgtca gcgttgctgg gtccgtcctg ctttccatat ttgcgtattg ctcatcggtg 98760
ggatgaattt ggtctcctcc ccgctgttgt ccgccggcag tggcgtggtt gctggcggtt 98820
gtcgttgtcg taccggcaaa gacggtgaga tccaatagcg actgctcgtc gaagggacag 98880
tacgctatca tgaaacgata gggtgccaac gcgcgttgga tgcgcagttc gcacatctcg 98940
ttctgacact cgtggcactg cagggcgcct aggatcaggt ccgagacagc gccgcagcgg 99000
taggtaccca tggcgttgtt agtatcgaac tggtcaaaaa attggggcgt accggtgact 99060
tgcaacgcgc gacggcgtag cgagacggcc acgcgcgaga aagagcacac ataggccatg 99120
gcgcggtgca tgggttgcga gaaggtctcg ggcggacgct tctgcagatc gcagacgtcg 99180
tcgcgtagcc aggcgctcat ttgaccgggc ttcttgacta gccgtttgag cgtgctgcaa 99240
tggtcgcccc agccgtcctg gtggtccagg atgcagccca ggtccaggtt gttgagtttg 99300
ttgaagagta gctgacgcat gccgcccacc gtctccagat agggatcgtg cgggttgacg 99360
ggtagcccgt gcaggtggtg gtacttcatg tagctgagcg tttcgtcgat gatggccagc 99420
aacgtgtgca agttgggagc gttgtacacg gcgaagatct tttccaccac cagcttgcgc 99480
agcaacggtt cctccagcca atcgaactgt tgacgaatgt gcaacaggta gtcggtgtgc 99540
atgagctcgt cgtgtgacag caggatgcga ccgcgcggct gatgatcttg cgggaaggcg 99600
gtggggacct tgagatcggc ggggtagggt gccagacgta gactctcggc cgtgtagcgc 99660
tgaaggtcgt aaacgggcga ggtagaactc ggtgaggtac ccgacgaggc ggcgccgcgc 99720
tgcagacgcg ctcttttttt cttttcgatc aaacggctga gttgctgtag ttcgtcctcg 99780
tccatggcgt ccagttcgtc gtcaataagc gccagcatct gttgttgttg cggtccggcg 99840
gacgatccgt gatgattatt ggctgaggag gggtgagaag aaccgaaagt cgtaggacaa 99900
ctgggaactc ggcgacgaag atgcgtcgaa tcgccgccgt gatggtgcgg ttcgccgtca 99960
tcgttgtcgt aagacttacc gtagtggggg ttaaggggca ccgaggcgga cgcggccacg 100020
cgtcgcttga aagaggagga cgccctatgt ccgccacgga agcccgcggt gcccatgatg 100080
atgtgtccgc cggtgccccc gagtgcgtgg cgggaggagg gtggaagggg aggaggatag 100140
tggtccggat cgccttcggt atcatcgtct ttgctgtagc ggggtcgtcg tgcggggacg 100200
cagggtcggt gatgatgcga ggcggcgccg acggtatctt ccgcgagatg gtgttcgctg 100260
gcggctgctc cgttccgtgt cgacggcgag gttggacttc gctcgcgtcg gaacttccgt 100320
ggcacgggtt cgtaatccag acagaagcgc cgtgcgcgac gggcgcggcg ttcgcgctcg 100380
ctcagggaag ataacgacgg agcgtcgtga cggccgcgtg agtgcagctc catggccgcc 100440
gtcgctagga aggtcacgtt cgggcacgct gatgtatata tagatgagac cgctgccggg 100500
gggcgggtca ccggcgccgt ggaaagtgag gctcagacgg cggtcgccgg cggcacgggc 100560
gcgtcgggcg gtctgatttt gatggaaatg tggacgtttt tggcgttgga gtgacacttt 100620
ttggtgaaac agcggctcca gaggctggcc cagagcgcgt agctgtgctc ggtgcgcagg 100680
tcgatgaaca cctgcacggt ctcttgcggg ttgcggtgcg tgtagttgag acagcgaaaa 100740
tcccgcgtgc gcgcgccgtc gcgccgcttg acggccacgc agcaggcgcc gtggggctga 100800
aagaggagga cgtggggcgc ggtaaactgc tcgctgacgt gcggttcgta gtgttgcgtg 100860
aggtgctcga gcagcggcgg ccacacgcgg gtgacgacga gccgctgcaa gtccgtgtcg 100920
gaaatcgcag cggcagtggc gccgtcgcca ccgtacaggt gataggcgag cacctcggtg 100980
agaccgcggc gtcgataacg cgtcacgtta agcgagcgcg tctcgataaa gttggcttcg 101040
gtcgaggggc agattttgtc gcgtacgctg agaatgacgc gtggcggcgg cgacaggggc 101100
aacgcgggca ggtcgtgcgg cgggtggtgg tgaagcaggt tacgcagatc cagttgggcg 101160
cgcacaaagc ctagcgggtg ttcgcggtag gcgtcgggca cgatgaacag cggcaacaga 101220
cggcgatgca tgaaatagcc gtcgtcttgg tccattttat acatgtaggg cagacgtaca 101280
gagcgtccat ggtggtagat gcctgtgtct aggctgctct cgggatgcga gatggggtcc 101340
agcagcgtgt gcagttcggc gtcgagacag acggcgtgat tgagcacctg cgccacggcg 101400
cgtaaaacgc tggggtgtac ggcgacggtg caggcgggga acggcgtgat gatgcgcagc 101460
cccagtttgc ccttgcagcg gcagtaaggg ggtgacgtgt caacggagga cgttgttttt 101520
tggaaaacgc cgttatccgg gacgttattt ttatcctctt tcccgtcttc gtcttcctct 101580
gtgtcgcgct cgtcccggta atcgagatag tcgtcgtcat cgaaaggcgc gccggccgcg 101640
tccacgggca cgctgttggg tgggcacgcg cttttgaaga aatagaccgg gtgccggtcg 101700
gggtgcgtgt agccaaagag gctcgcccat acggtcatcc agacgcgtcg tagtccgcga 101760
catagctcaa agacggtgtg tcgcgccaga ccggagacgc cgtcgcgcag ccgtaaatca 101820
aagtcggcca caaaattgaa gacgggcaga cgttcgttga agacttcgtg tcgcgtgtag 101880
tagaactgtg tctcggggct ggtgctggcc acgtcgtcgt cgtgtagcca cacggtctcg 101940
gtcagggcct cgtccgagaa acggctgtcg ggtacgtgac ggagcaggtc acgcggaaag 102000
aggctgcgat gccaggtttc ggaggccacg gcgcagaaga cgtgctggtc attgggcagg 102060
tgtacgcggt agacgggcag cggtcgctcc agcagcggtg ccagcgcggg ctcgggtagc 102120
aggtagcgac gttgcgagta acgcgttagc gtgccggtgg tgtaagtctg ggctgtgcgt 102180
agcgaggcgc atagacgtaa caagccggac agggagcgtt ccagcgggga gaagacagac 102240
tcggaaagcg tgttgatgcg ttcgagctgg cgcgccagct gcgtggaggt gccgaagaag 102300
cccgccaggt gcgtgccgtc gatgcggccg ccgtagccgg ccagccccaa gccgtgcggg 102360
ctggtcgccg agtgggggga ttcgtcgaga cgcagtaggt gcgtctccac gtagtcgtgt 102420
agaaagttgt cgagcgagaa gtatttttgc atgacgtcca gcagctcggt ggaaagccgg 102480
cggcccagaa aacccggttc gcgcgtgcac tgcgcttcgg gcgccgcgtc agcgtcgtaa 102540
gccaccacgc gccggtactc gagcaaccgc gcgcgtgcca gcgccgtgcg gtaggccagg 102600
tagacgtagt gcacgcagac cgtgtcgggc agacgcgcac gttcgcggaa cgcgttgatc 102660
tgcgtgtcca cctgctctag ctcggtgtag tcgcggcggt tgcgcgcgac ggcgtacgcc 102720
acgaaagcgg acacgcgctg acggaagggc gagcccagta gcagacgcgc gaactcgccc 102780
atggaggcgt gcgtggggat gatggtgccc aggtcgcgcg tgcagaagct gcgcacgtac 102840
tcctccacgg tggagatggt gctgtactgg ccctcgaata ggtagtaggc catggtcagc 102900
agcacctggc cctcggtgtg cccgaagacg ctgatgaacc acgagggcga ggtggggcag 102960
aggaagacct ggttgagatg acgtagcacg gccgcgtggt gaaagtacac caggtgcttg 103020
aattcgcgca cctcgccgcc gtgttcgggc gagagcacgg gcgtgcggaa aagatgccgg 103080
tagagcggtt gcgtctcggc ctcgtccaga ctggcgatga gcgccgagag ggggatgggc 103140
tggcgcgcgg ccaggtagcg cgagagctgc agcgtttcgt tgttcacggc gaagacgggc 103200
gccacccgcc gcgagtccga gcacttttgc gtctgtaggc agaagtaaac acgtcgcgag 103260
acctggtgtt tgaccagcag ggggaagacg cagtggtccg tcggtgtctg cgagagtacg 103320
ttggcgacta tatgagcaga atcatactct gttgcgaaca gaacgagcgt catcgtcgcg 103380
ccggcacgat gcagctggcc cagcgcctgt gcgagctgct gatgtgccgt cgcaaagccg 103440
cgcctgtggc cgattacgtg ctgctgcagc ctagcgagga cgtggagctg cgcgagctgc 103500
aggcgtttct ggacgagaac tttaagcagc tggagatcac cccggccgac ctgcgaacct 103560
tttctcgcga cacggacgtg gtgaaccacc tgctgaagct gctgccgctc tataggcaat 103620
gccagagcaa gtgcgcgttc ctcaagggct atctctcgga gggctgtttg cctcacacgc 103680
ggccggcggc cgaggtggag tgcaagaaat cgcagcgtat cctagaggcc ctggacattc 103740
tcatcctcaa actggtggtg ggcgagtttg ccatgtccga ggccgacagc ctggagatgt 103800
tgctggacaa gttctccacg gatcaggcct cgctggtgga ggtgcagcgc gttatgggcc 103860
tggtggacat ggactgcgag aaaagcgcgt acatgctcga ggccggcgcg gctgcgacgg 103920
ttgcgccact gacgccaccg gcggtcgttc agggggaaag cggcgtccgc gaggacgggg 103980
aaacggttgc cgccgtgtcg gcctttgcct gtccctcggt ttcggactcg ctgatccccg 104040
aggaaacggg ggtcacgcgt cctatgatga gtttggctca cattaacacc gtctcctgtc 104100
ctaccgttat gaggttcgac cagcggctgc tggaagaggg cgacgaggag gatgaagtga 104160
ccgtgatgtc gccgtcaccc gagcccgtgc aacagcagcc gccggtcgag cccgtgcagc 104220
agcagcccca gggacgcggg tctcaccgtc ggcgctacaa ggagtcggcg ccgcaagaga 104280
cgctgcctac gaatcacgaa cgcgagattt tggatctcat gcgacacagc cccgacgtgc 104340
ctcgggaggc ggtgatgtca ccgaccatgg tcaccatacc tcctccccag ataccctttg 104400
tgggttccgc gcgtgaactc aggggcgtga agaaaaagaa acccacggcg gcggccttgc 104460
tgtcctccgc gtgaacagcc tggcacgttt tggaaaacgt acgtgatcac ggacacgacg 104520
agtacggggt ttctcataga cgtactttat taggtcaggg atgacgggga ggtttcgggc 104580
cgacgtcaaa aataacgtca ttcgtgttga cagggctttc tgcgtcggag ctcttttcat 104640
cttcttctgt ctcgtcgacg tcatcgtcta ccggcgaggg tgtccgttgc agcaacgcgt 104700
gctcgggcgt gtgggtgaaa ccgatgtcgg gggtgggcgg cacgatcatc tgtcctaggg 104760
ggtgactgcc caccggcaga taggtaaagc ggtgggtggt aaaaaccgct ttggctacgg 104820
tggtgtgtgg ggagatgcag acggtggtgt gcgaagtgtt gaccaccgtc acgccggccg 104880
cggtacccgg gagccagatg gtgggtcgga tgatgagatc cgattgacta aactggcgca 104940
cgcccactat gagggcgcag ataccgggcg cgtgcacgta ggccgcgtca aaatagacgg 105000
tttgcgtgtg acccggaccg atcaccagcg tctgacgggt acgtaacgaa aagaaacggt 105060
gttcgttggg cggcggcaag ttcatgagct gccagggttc tggtacaaaa caggggaaaa 105120
cgccgatatc gccttcgatg gtgcccggaa agatggactg aaaagtgtcg ttgaggttga 105180
cgacatccaa ctgcgggact tgcagcctgg attccagcag ctcgggcatg caaacgaatt 105240
gcgcgtccag gcatttgtaa aaggtaatgc cgaaaaaacc ttcggggata tagaggctga 105300
cgcccagcga ggtgggcact ttgcgctcgc gtgatagcca aatgatgtgt ttattgtaaa 105360
aggccagctg cgtgtggcat tgtttgacga tgaaactgga aggcatccac ttgtaaggaa 105420
ctttgagcgg tgacggtaat ggcgacgacg cttcatcctc tcccggatgc tgctctttgt 105480
cgtatttctc ctcggtcgat tggggcagcg taaatgtggt ttgaaaatcg ctatcgctag 105540
cgaaacgcac gcagtaacgc atgttgacgg atttctcggc taggatgatg gagcctgatg 105600
acgatgcgga ctcttccttc attattaacg taggggtctc ccagaatcgc tgaaaacggg 105660
agcgcggcag ccgcgacagt accagttgag agtcgattcg gtcggtcaac atcgtaagca 105720
tcgtggcggt ggtgtgatgg agtggaacac actagtatta ggtcttttag ttttatcggt 105780
agtggcagag agttctggta acaattcatc cacgtcaacc tctgcaacta catcaaagtc 105840
ttctgctagc gtatcaacta ccaaactaac aacagttgca acaacttctg caacaactac 105900
gacgactacg accttatcga caactagcac taaactcagt tctaccaccc acgatcctaa 105960
tgtgatgaga cgacatgcga acgatgattt ttacaaggcg cattgcacat cgcatatgta 106020
tgagctctca ctgtccagct ttgcggcctg gtggactatg cttaatgctc taattctcat 106080
gggagctttt tgtattgtac tacgacattg ctgcttccag aactttactg caaccaccac 106140
caaaggctat tgagggtgga cagatttaca gcccggcggt gttccggcgg ggtaaggttt 106200
acatacgtgg gtgaccggag gctaaagtta cgaatctcat ctagaaacag cagcgagtct 106260
agatagtccc acaggggatc tataaatgtt ctctgaaacc ccattgatgg tgacgtaggt 106320
gtagttttgt tactatcgga agctgttttg ttttccacga acatggtttc gttgtaatat 106380
aaggagctca tgtcgagagt accgtaaata gtgtacggcg tttcgttacg gattagtacg 106440
tgcgtgtttt tcataaattc tgacacggcg gttcggttgc ggcttggttc acaaaaagga 106500
ttttgccggt aacgtagagt ggtatacacc cacgttgcta ggtcccttaa ctgtgtggcc 106560
ataatggact tcataaagct gctatcagga cgataagcaa ttgtagacgt ggaaacccgc 106620
cttgcggcgg tagtaatact ataagtcacg ttagtagtga cgttgagagc ggcagacgtt 106680
gtataggaaa agtatggcgt agtagtactc tgagttttct tagctttttt ttcgaattgt 106740
tccttaacgg gcgcttgttt acgttttagt tttcgcatag tgttttttaa cttggtgccg 106800
ttaatatact tggggacgcg aaatagattc cggctcatgg cgttaaccag gtagaaactg 106860
tgtgtacagt tgcgttgtgc gtaacgtaaa agcagggcgg ttaaacctag aaaataaatc 106920
gtttgactat ctacgttaac cttagtcgga cccacgtaca atttggtgtt ccaacgcggt 106980
acattgaaaa acatggggtt gaacgtggtg aaattaccgc aaccttgttc gccagtatca 107040
ttacgtttgg aaacgtttag catttcggaa agacaagtca tggaaggcac agtaccacaa 107100
ggtgggggtc tgaatgttat cgttttagcc gtatgattgt actgtgagta aacgtatttt 107160
gcgggttttc taagctgggt actataaaaa tcaaaccaca gataggttat actataattc 107220
tgaatggggc ccgctaaaat gtagtattgt ggaaactctg tcatgttcat agtgagattt 107280
ttaaccggtt gtttacttac attgtatttt gtagaaatag tcgtttctag ttgtctcaaa 107340
atttctaact taagctgatc taatttatat ttgcctatct tagacagtac caagcccctc 107400
caaggacgat tataaagcgc ttttgacata actttacagt ttatgaaaga aacaagcaag 107460
aaagatatag atattagaaa caccatctta gggacgtctc tcaccatcat ctcttttctc 107520
cccatgacag aggaggagac cccgcaccgt ccgtctgcct tgtggtttgg cttgcctgcg 107580
tgtactcact gctgattctg gtcgttttgc tgctcatcta ccgttgttgc atcggcttcc 107640
aagacgacct agtctcccgc accttggctg tgtaccaagc ttgtatccag ggcccgatat 107700
gtaaccagac ccataacagt acctcgtaaa taaagacgca cagacctcac gcatatagta 107760
ccatcacacc gtgtggcgtg tactttatta caacgagcaa gagtgcccct aagtattggg 107820
gcccgtaccg ttttagaaga ttttgtgtga atgtctttaa cttttctgtc ccttttctca 107880
taaactgtca ggttctacag tcagcatgtc ttgagcatgc ggtagagcag atagatgccg 107940
atgatggccg atagcgcgta gacggacatc atgaggagac gactgtcggt ggcgtccacg 108000
acgacgtcag ttacttctag gaccgtaccg tttttcaaaa gcatgaggta gtgagttcgc 108060
ggagatgaga ccaccacttc gttgtaggga tccagggcga aaaggacgtc gtccgagtcg 108120
tgcatgtaca tgatgttgat gacgccttgc gtgtcgtcgt attctagcag ggcgctttgg 108180
caaaaggcgc agttttctag tgaaatgttg agcgccgctg tgatgctgtg tgtggtgtgc 108240
atgttgcgcg ttagttcgca tttagtttga ctgtccgttt gggtgatgat gaggctctgg 108300
cctacgacgg tggtggagac agggtaggag atacctttga tcaggtactg gtttgttacg 108360
acataactga cgtgttcgga gacggttagc gcggagaagg attcgccgag cggcagacaa 108420
aacaggtcgg ggaaggtttc cagcgtgctt ggttgcatgg tagataggat ggagagggcg 108480
gcgggaacgg tagcaggaac ggtggcatcg gggaagagac gcgtgaggcg ttcgagcgag 108540
tgatcgcgtc gcccgctact ggaacagggt gtgtacaggt cgctgaggta ttcgtggtgc 108600
ggatgagcta gcaactgcgt aaagtgtgat agctcggcca atgaacagag gcccgtttct 108660
acgatgaaga tttcgcgtct ctccgtcgta tgtaccaaca tggagtggac gaggctgccc 108720
atgaggtaga gttcttggcg cgcgaaggct gaaagaaaag aggccaggtg cgttttgtgt 108780
aattgtaggg caaagtcggc gatctgtcgt agtgcccact ggggaatgag atgttgctga 108840
ttctgtttag aaagtatgta gaccaggcgt acgaggctgg tgatgtcggt gatctggtcc 108900
ggcgtccaga gggctcgttt ggccaggtcc acggctgtgg gatatagcag caatgtggtg 108960
cgtggtggtg tttgtgagag gcaggtgatc ataaattctt gtatttgtaa gagtgcggcc 109020
tggcggtcta gggctcgtgg gatggagatt tcggtgccgg cctcttcttg tcgggctgcc 109080
gcgaacagtg ctaatgcgta ggcgaaggcc atttctaccg tgcggcggtc caacatttga 109140
catcgaccgc ttttgagtac gtctacagcg taacggtgaa agctgttacg taacagtgcg 109200
ctgaggtcca ggtagttgaa gtcgagtgcg gcgtcgagaa agtccgagtc tttgagatag 109260
gagtgacggt ttagttgagc tttcttaact agtaccagga gctcgtgttt ttcagtttgt 109320
cgtagtataa agttgtcgcg ttgatagggc gctttgaaga gtacgcgtgg aagatgaccg 109380
aagataagca gcatgggtgt gtcgtcgtct atagataccg taactacgaa gaagtcctcg 109440
gtcagtgtga ttttaacgta acgtagttcg tccatgaggt aaaagccctg gtgcagacag 109500
ggcgtaacgg tgctgaaaag cagatcgtgt ccatcaaaga ggatacaggt ctggttaaag 109560
tgtggccgat gtagtcccga ggtggtgtgc gatcccttcc agtcgtgtgg agtggtttgg 109620
ggtggcatcc aaacgtgagg tattgacaga tcaatgggcg gtggcacggt ggtgggctgc 109680
tgacccaggc tgtcttgtgc cttcagctgc tgcgaaaaag atcggtagct ggccaggtct 109740
ttggatacca atgcgtaggt gttaagtctc tgttggtatc tttctagggt ttcggtcaga 109800
tctacctggt tcagaaactg ctccgccaga ggacccgcaa aaagacatcg aggcatatgg 109860
aatacatagt attgattata gctttggaaa aagttgaaac tgatggcgtt ttccctgacg 109920
accgtgctgt tacggaggct gctgttgtag gtgcactggg tggtgttttc acgcaggaag 109980
cggatgggtc tcccgtaggt gttgagtagt aggtgaaatg cgtgagggtc cagcgcttcg 110040
gatgcggcgt ccgcgccata tcgttgcgaa ggtaggtgac tgaggaggta gacggtgaag 110100
acagtgaggt agggggggag gccgggccgc atagcgcggc tgcgccgctg ggttcagcgg 110160
cgtgatccag gtggtggttg gcgttacacc cgagagaagg agagaaagga tcccaggaag 110220
gggcacccgg gtgtggcgct acgggttaca aaagtcgcgt ctctgtctat ttaatacgat 110280
gtcattggcc gctgcgaagg aagaagaggg gacacgcggg taagccatgc cgtccgggcg 110340
tggggacgac gctgattcga cggggaacgc tctgcggaga ttgcctcacg tgcgtaagcg 110400
gatcggtaag cgtaagcacc tggacatcta ccgtcgcctg ttgcgggtct ttccctcgtt 110460
tgtggccctc aaccgcctgt tgggaggcct tttcccaccc gagctgcaaa agtaccgtcg 110520
ccgtcttttc atcgaagtac gattaagtcg gcggattccc gactgcgtgt tggtgttttt 110580
accgccggac tctgggtcgc gcggcatcgt gtattgctac gtgattgagt tcaaaactac 110640
gtactcagac gccgacgatc agtccgtgcg gtggcacgcc acccacagcc tgcagtacgc 110700
cgagggcctg cgccagctca agggcgcctt ggtggacttt gattttctgc gtctgccgcg 110760
cggtggcggt caagtctgga gcgtagtgcc cagtctggtt ttttttcagc aaaaggccga 110820
tcgcccatct ttttaccggg cttttcgttc gggccgtttc gacttgtgta ccgattctgt 110880
cctggactat ctgggacggc gtcaggatga gtctgttgca caccttttgg cggctacccg 110940
tcgccgtctt cttcgaaccg cacgaggaaa acgtgctgcg ctgccccgag cgcgtgcttc 111000
ggcggttgct ggaggacgcg gcggtgacaa tgcgcggcgg gggctggcgc gaggacgtgc 111060
tcatggaccg ggtgcgcaaa cggtatctgc gtcaggagct cagggatctg ggtcacaggg 111120
tgcagactta ctgcgaggat ctcgaagggc gcgtgtccga ggcggaggcg ctgttgaacc 111180
agcagtgcga gctcgacgaa ggaccgtcgc cgcggacgct gctacaacca ccgtgtcgtc 111240
cgcgttcttc gtccccaggg accggcgtgg caggagcttc tgccgtccca cacggtcttt 111300
atagtcggca cgatgccatc acgggacccg ccgccgcccc gtctgacgtg gtcgccccgt 111360
ctgacgcggt cgccgcgtca gcggccgccg gtgcttcttc tacctggctg gcgcagtgcg 111420
ccgagcggcc gttgcccggg aacgtaccta gctactttgg aatcacgcag aacgatccct 111480
ttatccgctt tcacaccgat tttcgcggcg aggtggtcaa caccatgttc gagaatgcct 111540
ctacttggac tttctccttt ggtatctggt actatcggct caagcggggg ttgtacacgc 111600
aaccacggtg gaaacgagtg taccatctgg cgcagatgga caacttttcc atttcgcagg 111660
agctgctgct cggcgtggtc aacgctttgg aaaacgtgac ggtgtatccg acgtacgact 111720
gtgtactctc cgatttggaa gccgccgcct gtctgctggc cgcctacgga catgcgcttt 111780
gggagggccg cgatccgccg gactccgtgg cgacggtgtt gggtgagctc cctcagctgt 111840
tgccgcgtct ggccgacgac gtgagtcgtg agattgccgc ttgggaaggc cccgtcgccg 111900
cgggtaacaa ctattacgcg tatcgcgact cgcccgatct acgctactac atgcccctaa 111960
gcggtggtcg tcactatcac ccgggcactt ttgatcgtca cgtgctggtg cggcttttcc 112020
acaaacgcgg cgttattcag catttgccgg gctacgggac gataacggag gagctggtgc 112080
aagagcgtct gtcgggccag gtgcgcgacg acgtgctttc tctctggagt cgacgtctgc 112140
tggtcggcaa gctgggtcgc gacgtgcccg tctttgtgca cgaacagcaa tatctgcgtt 112200
cgggcctgac ctgcctggct ggcctgctgt tgttgtggaa ggtgaccaac gcggatagcg 112260
tcttcgctcc gcgcacgggc aaatttacgt tggccgacct gctgggttcg gatgccgtag 112320
ccggcggcgg gttgcccggg gggcgcgcgg gcggcgaaga ggagggctac gggggacggc 112380
acgggcgggt acgtaacttt gagtttctgg tacggtacta catcgggccg tggtacgcgc 112440
gcgaccccgc ggtcacgctg tcgcagctct ttcccggcct ggctctgttg gccgtgaccg 112500
agagcgtgcg cagcggctgg gatccctcac gtcgcgagga cagcgccgga ggtggcgacg 112560
gcggcggcgc cgtgctcatg cagctcagca agagcaaccc cgtggccgac tacatgttcg 112620
cgcagagctc caaacagtac ggcgatttac gtcgcttaga ggtacacgat gccctgctct 112680
ttcactacga acacgggcta gggcggctgt tgtcagtgac cctgccgcgt caccgtgtgt 112740
ccactctggg ctcgtccctc tttaacgtca acgatattta cgaactgttg tactttttag 112800
tgttggggtt tcttccgagc gtggcggtgt tgtaatttcc accacgtgtc gctcgctgca 112860
taaagggcga acgtcctcgg agagggtata ttcgttcggc gagagcgggc ggcggtggtg 112920
ggtatgtccc cttctgtgga ggagactacc tcagtcaccg agtccatcat gttcgctatt 112980
gtgagtttca aacacatggg cccgttcgaa ggctactcta tgtcggccga tcgcgccgcc 113040
tcggatctac tcatcggcat gttcggctcc gttagcctgg tcaacctgct gactatcatc 113100
ggttgcctct gggtgttgcg tgttacgcgg ccgcccgtgt ccgtgatgat ttttacttgg 113160
aatctggtac ttagtcagtt tttttccatc ctggccacca tgttgtccaa gggtatcatg 113220
ctgcgtggcg ctctaaatct cagcctctgt cgcttagtgc tctttgtcga cgacgtgggc 113280
ctatattcga cggcgttgtt tttcctcttt ctgatactgg atcgtctgtc ggccatatct 113340
tacggccgtg atctctggca tcatgagacg cgcgaaaacg ccggcgtggc gctctacgcg 113400
gtcgcctttg cctgggttct ttccatcgta gccgctgtgc ccaccgccgc tacgggttca 113460
ctggactacc gttggctagg ctgtcagatc cctatacagt atgccgcggt ggacctcacc 113520
atcaagatgt ggtttttgct gggggcgccc atgatcgccg tactggctaa cgtggtagag 113580
ttggcctaca gcgatcggcg cgaccacgtc tggtcctacg tgggtcgtgt ctgcaccttc 113640
tacgtgacgt gtctcatgct gtttgtgccc tactactgct tcagagtcct acgcggtgta 113700
ctgcagcccg ctagcgcggc cggcaccggt ttcggcatta tggattacgt ggaattggct 113760
acgcgtaccc ttctcaccat gcgtcttggc attctgccgc tctttatcat tgcgttcttc 113820
tcccgcgagc ccaccaagga tctggatgac tcctttgatt atctggtcga gagatgtcag 113880
caaagctgcc acggtcattt cgtacgtcgg ttggtgcagg cgttgaagcg ggctatgtat 113940
agcgtggagc tggccgtgtg ttacttttct acgtccgtcc gagacgtcgc cgaggcggtg 114000
aaaaagtcct ccagccgttg ttacgccgac gcgacgtcgg cggccgttgt ggtaacgaca 114060
accacgtcgg agaaagccac gttggtggag cacgcggaag gcatggcttc cgaaatgtgt 114120
cctgggacta cgatcgatgt ttcggccgaa agttcctccg tcctctgcac cgacggcgaa 114180
aacaccgtcg cgtcggacgc gacggtgacg gcattatgag cggcggcgct gtacggcagc 114240
ggggagaaaa gtggcagata aatcacgtca ggttcacacg tcgttagcca gcgtcggcat 114300
atgaagggcg cgggcggcca gtacggcctc tgggctgaga caggacgagg cagggtgaga 114360
aagaggagga tgggggggac cggggtggtg gtgctgctgc tgttgtgggt gcggacggtg 114420
cgggtgccgg gacagcgtgc cggcgaacgt tctgtaatct tccataataa aagtaaaaat 114480
gcccgtctcg tgtcgactcc gctggatctc gaaggcgtcg ggggtaatgc gcatcttgcc 114540
ggtgccgatg agataaaagt accacatttt ttgacagatg atgcgaatca agggttcgta 114600
cgcttcggca ccccagtggc gcgtgaagaa ggccgccaga cgaaacaagc ggtgtccgta 114660
gagcgtgcct agggagaaga ggatgttgcc gttgcgcgcc aggtcttcgg ggaaaacgac 114720
cggcaggccg gtgtggcgct gcacaaagcg cgtcagcagt ccgccgctca agcgcgggtg 114780
acacaggcgc tggctgagac gggcggcgcg cgtttcatcg aacacggccg cctcaaagtc 114840
cagccccggg aaggcctggc gcagttcgcg gtacagatga ggccagtagg gttgcggcgt 114900
cttgcgacta agcacggcgt ggtccgagac acccaggttg ttcatggttt cgcgcagtag 114960
cagcgtttcg agaccgcggt gaaagaggag gacgcagatg aggcgtacga tcttgagttc 115020
ttccaaacgc agcgagctca gcggctgtcc gcgcgacatc ttctcgctaa tctgtaatat 115080
tagatgattg gcgcaagtaa aggagaattt gcccgtgcgg acccgcggga cggcggggtt 115140
ctcttcgtcg cgggccatca tcgttcgctc ggtgagcggg tagcgacggt gacgacaatg 115200
acgatggacg agcagcagtc gcaggctgtg gcgccggtct acgtgggcgg ctttctcgcc 115260
cgctacgacc agtctccgga cgaggccgaa ttgctgttgc cgcgggacgt agtggagcac 115320
tggttgcacg cgcagggcca gggacagcct tcgttgtcgg tcgcgctccc gctcaacatc 115380
aaccacgacg acacggccgt tgtaggacac gttgcggcga tgcagagcgt ccgcgacggt 115440
cttttttgcc tgggctgcgt cacttcgccc aggtttctgg agattgtacg ccgcgcttcg 115500
gaaaagtccg agctggtttc gcgcgggccc gtcagtccgc tgcagccaga caaggtggtg 115560
gagtttctca gcggcagcta cgccggcctc tcgctctcca gccggcgctg cgacgacgtg 115620
gaggccgcga cgtcgctttc gggctcggaa accacgccgt tcaaacacgt ggctttgtgc 115680
agcgtgggtc ggcgtcgcgg tacgttggcc gtgtacgggc gcgatcccga gtgggtcaca 115740
cagcggtttc cagacctcac ggcggccgac cgtgacgggc tacgtgcaca gtggcagcgc 115800
tgcggcagca ctgctgtcga cgcgtcgggc gatccctttc gctcagacag ctacggcctg 115860
ttgggcaaca gcgtggacgc gctctacatc cgtgagcgac tgcccaagct gcgctacgac 115920
aagcaactag tcggcgtgac ggagcgcgag tcatacgtca aggcgagcgt ttcgcctgag 115980
gcggcgtgcg atattaaagc ggcgtccgcc gagcgttcgg gcgacagccg cagtcaggcc 116040
gccacgccgg cggctggggc gcgcgttccc tcttcgtccc cgtcgcctcc agtcgaaccg 116100
ccatctcctg tacagccgcc tgcgcttcca gcgtcgccgt ccgttcttcc cgcggaatca 116160
ccgccgtcgc tttctccctc ggagccggca gaggcggcgt ccatgtcgca ccctctgagt 116220
gctgcggttc ccgccgctac ggctcctcca ggtgctaccg tggcaggtgc gtcgccggct 116280
gtgtcgtctc tagcgtggcc tcacgacgga gtttatttac ccaaagacgc ttttttctcg 116340
ctacttgggg ccagtcgctc ggcagtgccc gtcatgtatc ccggcgccgt agcggcccct 116400
ccttctgctt cgccagcacc gctgcctttg ccgtcttatc ccgcgtccta cggcgccccc 116460
gtcgtgggtt acgaccagtt ggcggcacgt cactttgcgg actacgtgga tccccattat 116520
cccgggtggg gtcggcgtta cgagcccgcg ccgtctttgc atccgtctta tcccgtgccg 116580
ccgccaccat caccggccta ttaccgtcgg cgcgactctc cgggcggtat ggatgaacca 116640
ccgtccggat gggagcgtta cgacggtggt caccgtggtc agtcgcagaa gcagcaccgt 116700
cacgggggca gcggcggaca caacaaacgc cgtaaggaaa ccgcggcggc gtcgtcgtcg 116760
tcctcggacg aagacttgag tttcccaggc gaggccgagc acggccgggc acgaaagcgt 116820
ctaaaaagtc acgtcaatag cgacggtgga agtggcgggc acgcgggttc caatcagcag 116880
cagcaacaac gttacgatga actgcgggat gccattcacg agctgaaacg cgatctgttt 116940
gctgcgcggc agagttctac gttactttcg gcggctcttc cctctgcggc ctcttcctcc 117000
ccaactacta ctaccgtgtg tactcccacc ggcgagctga cgagtggcgg aggagaaaca 117060
cccacggcac ttctatccgg aggtgccaag gtagctgagc gcgctcaggc cggcgtggtg 117120
aacgccagtt gccgcctcgc taccgcgtcg ggttctgagg cggcaacggc cgggccctcg 117180
acggcaggtt cttcttcctg cccggctagt gtcgtgttag ccgccgctgc tgcccaagcc 117240
gccgcagctt cccagagccc gcccaaagac atggtagatc tgaatcggcg gatttttgtg 117300
gctgcgctca ataagctcga gtaagagaga cgctatattt agggcttccc tctctttttt 117360
ttctacaccg tgatacccta ataaagcaca ccgcggttat tatcaacgtc tctgtgtttt 117420
tattatttag aaataaatac agggaatggg aaaaacacgc gggggaaaaa caaagaagtc 117480
tctctctaga tgcggggtcg actgcgtggg gtgctggaag tggaagcggt gctgatgggt 117540
gagggtcgtg gcgcgggcac ggaccgcaac gtgctgctga tgtctgccgc ggtacgcacg 117600
tcgccgtcca tgtcgctgcg cagataagag gtaggtcgta gtgcggcgtg ctgcacgctc 117660
accgttaatg gtaccaagtc gtcaaggctc gcaaagacgt gccacgaggg gatgacgagc 117720
gtgagagccc cgttgttacc gcttcgacgt ctttgtccgg tcaggatcag tgccggggac 117780
agtccggctt gggtgtccga gtcctcgtcg ccgctggctt cctcgaagcc ggcaaacatg 117840
gcttcggaca ggggggtcgg cgtcggtgtg gaggagaggt catcttcgtc gtcctcttcc 117900
tcttcttcct cctcttcctc ggtgggtggt aatccggggg actgcgggag aaactcggag 117960
acggcgccgc gcatgacgtt gctccgtgga aagagaccgg cgcgcagctg cacctgggga 118020
cgcttgattt tgtccggttt accgggtgtg agagtccaaa acccacggcg gaaaaagtgg 118080
atgcggccta gcggctgtcg gtgttccaaa tgaacggcct gatcgccggt cagcgtgacg 118140
cggagggtga ttcgcacacg atcgggtagc gggccggctt ctatggagac gcccgggatg 118200
ttttccggga aaaagatggt gtcgtgagtc tgattggtct cgaaagcatt ctggatctgc 118260
acgatgtact cgggatgtat gcgcgtcagc gtaaaacttt tgggaatcaa cagctggaag 118320
ccgttgtccg gcaagcgtcg taggtgcggg tacggattgt gtcgcgccac cacctcggcg 118380
cgatgcgtgt aaaccgaaaa gtgcagaaac acgctggtcg gcgggtgcgg tgagtcgtga 118440
tgcagaaaca gcatgatcca ttggcctcgt tcgtccgtct ccgttttgtg gatgtacgtg 118500
ttagggtccg aacaggccag ctgctccagg gcgtctacca gcgtcagcgg gatggcgccg 118560
gcgcgaaagg cgaactggct gacaaagatc tgccctgcct ccaaactgct gtcggttctg 118620
cggcgccagt tcggcgttac ggtcagtcgc acggcccagt ggtgagccgt gcggcggatg 118680
atggcgcgcg cttccattcg cggccgattt tcttcgccgc cgcgccgctg gctctgaaag 118740
aggtgcagtc cgctaacggg cacgcggtcc agcggcagcg caaaggccag taccgagacc 118800
gtgttgtttt ctgagcctgg cgtcaggcgt cgtgggccaa agttgttgag gtccaccagc 118860
agtcggtcct gttcgcccac cacgcagcgg cccttgatgt ttaagtcggt caggtctacg 118920
gtgtcgtgcg gagatttgtt ctcctgaaaa cagcagagaa ccgagggccg gctcacctct 118980
atgttggtac gcaggtccag gagtcgcaga cgaccggctt ccagcgagcc gccttccacg 119040
ttggtgatga gccgaagcac ctggcagtgc aggcgaccaa agcttccgct ggcggcttcg 119100
gcctcgctga tcgcggccgc ttccgacgag ggtccctcac cgggcgagga cgatgcctga 119160
gacattgcga aggcgggatg gggggagggt caggggatgc gcaaaggtga acgggtcttc 119220
gtgggaggtc gggaagggtt ccggcaactg tcgcaaatat agcagcggtg acaggtgtgg 119280
cggccaaaag ttgcgtgtct gagtggacgt gggtttttat agagtcgtcc taagcgcgtg 119340
cggcgggtgg ctcaacctcg gtgctttttg ggcgtcgagg cgatgcatgg cccgggcaag 119400
gcgtcttgcc ggtggcggcg acgtttgggt tgcgcagcgg gctgccatac gccttccaat 119460
tcggcgaaga tgcggtagat gtcgttggcg tcccagaaga attcctggta cttcagattc 119520
tgaccctgaa ccgtagccac catgggcacc aggttgcggg ccaggatgcc ggcctgccag 119580
ggcggccagg tgaacacggc cggattgtgg atttcgttgt cggaatcctc gtcggtgtcc 119640
tcttcgggcg cgacggtgga ctcggcctta aggcggccgc gtgtcataac gcccgacgtg 119700
cacgccgtcg ccgaggatgc tgatttgcgt ttgcggcccg cggaagtgga ggcgcccgcc 119760
atggcgccgc cgccggtgac gcggggcgtc ttgcgctcgg tggttacgag ttcttcgtcg 119820
gagtccgatc cgctggtcca gacgtcgtcg tcgccctggg cggcaccctc gtcgtgccgg 119880
tcccaggtgt gtcggtactc aagcttgccc tggatgcgat actggctggt gaaggtgggg 119940
tgctcgctgt actgaggccc gcgctgcagc agcaagtcga tatcgaaaaa gaagagcgca 120000
gccacgggat cgtactgacg cagttccacg gtctcgcgta tggcttgtac ctccaggaag 120060
atctgctgcc cgttcatcaa caggttacct gagatgctca ggcccgggat gctcttggga 120120
cacagcagcc caaaatgctc gtgtgaggta aaagccacat ccagcatgat gtgcgagatc 120180
ttgcccggtt tgattatcat atttttggga cacaacaccg taaagccgtt gcgctcgtgg 120240
gggcgcatga agggttgcgg gttgcgggtc atcgtcaggt cctcttccac gtcagagccc 120300
agcgtgacgt gcataaagag cttgccggag ggcacgtcct cgcagaagga ctccaggtac 120360
accttgacgt actggtcacc tatcacctgc atcttggttg cgcgcgtgtt ctccatggag 120420
caaaccagct cgtgcgcgca caccacgtgc cgcagtgcca cgtccttggt gggaaacacg 120480
aacgctgacg tgtagtagac gtcgggctct ttccactggt tctgctgacg cgtccaggcc 120540
agtcccgaga ccgtgagacg cgcctgccac atctgcttgc ccgacgcgtg aatcacagcg 120600
tcagctacgg gcaggtgtcg gtgtttgcgc tcggccgccg acgggtagtg gtgcacgttg 120660
atgctgggga tgttcagcat cttgagcggc agcgcgtaca catagatcga catgggctcc 120720
tggctggggc agatgcttcg gcccgtgggg ttgtgcacgt tgaccgacac gttctccacc 120780
tcgctgcccg taaagtacgt gtgctgcacc tgcagctgat tgtcgccgcg gtggcatggc 120840
gtcgagtcgg gcgtgtactg cgataccaag atcagcgagg gctggctcac gcgtacgtgg 120900
atacccgtct gcaggagtcg cgtctcgtgc ggcagcaccg gcgtatcgcc gcgactaaac 120960
acggctttca gcacgtgccc cgaaatggga cccagtacgg atatcatttc gggacaacgg 121020
cgaccgcgcg actccatgct gcctgcgcgt acgggtgtag gcgactgagc ggcgcgccct 121080
ctgcggccgc cgccttacat aggcaggcga ccaaacgcgg aacccgaaat aaaaacgttc 121140
tacacagaga caaccgcgga ttattgagtg tcttttttta ttacaaaaaa aagaggcgaa 121200
gccccaccgt caccacaccc catcacacac caccaccgat ttttttttgt tttaatcccg 121260
tatggcgcgg acgcctagtg tccgtttccc attatcaggg tcctctgttt agagatcgcc 121320
gcagaccatg gctaaagtga caggactcgt cttctctgtc gtattttccg taagcttaca 121380
gtcttgcggt tccgtctccg gggacgccag tcgcatgggc agcaggtcct ccagcgcgat 121440
ggaagcgccc agcaccgaga gctgctgttg cgacggcgaa tgggatgtgg accgcgagtg 121500
tagcgtggat ttgacttggt gcgtcattgc tgacaggcaa ccccgattca gcgtatgctt 121560
tgacgagata aaatagaggc gccccaggag cgcgtcccgt gggaacgtgg cgccgttctc 121620
gtcgctcacc agtacggtta attccaacca ggagcgcggt agccagaccg taacgggcat 121680
tttgagtccc tgacggttgt gtggtacaaa aacacccaga taaggcccgt aaaagcggcg 121740
gtagatacgt aacgtgtgcg agttcttcag cgtcaattcg taagggacgc gcacctccag 121800
tccctcgtcc gccgcgccgg agcgtggcgg tacaaagtaa ggcagtggcg cgtccgaaaa 121860
gaagggtcgt cgcaccgttt cgcgtcgcag ccgcaggcga aacgccactg ggtcggctgg 121920
cgcctcggtg cggtcgcagg tcacgttgaa acgtaatatg ccgtcttggt atagcgtgag 121980
tgacgacagc gtcaggtccg gcggtgattc gttcgggtct agctccaatc gtccaaagac 122040
ggagggtccc aatgtcttgg ccgtggtttc cgagaggcgc gccgagatac ggctggtgag 122100
tccacgcggc cccgagatgc cgccttccac tcgatgccag cacagcgcgt gtcgtacgcg 122160
caccgtcagc gtgggcgtca gatccgcgtc cgttgattcc gcggtatcag cgacggaagc 122220
cgcgttctcc gttacgttgt ttatatccag cgtcggctcg aacgtgagtt ctggcagatg 122280
cagcgccaga cagtcgtgta acgccgtgtg atgcgcggct ttacgtcgta gcggtagccg 122340
tttcaacagc ggcgtgatga tacggagcgc gaagagattg agtgataggc gcacgatggc 122400
catgcgcgtc agttgttggt caattaccga gcgcaggata tggcagcctg ggcgtgcggg 122460
aaagagagag aaggccgggc gcacgtcaga atcctcgtta gagaccacgc atagaatgcc 122520
gcgttcacga tcgtcgttgc ggtcatcctc gtcctcttct ttcttctctt gtttttcctt 122580
ttttttctcg ggctcgtggg aagccgccgt ttcttcttct tgcaacgtcg cgggggcggt 122640
ttgagactcg tcgttcgctt cccccaattg cagcggcgta gagagcagaa tctggaaggg 122700
atcccgcaat tcttcgggtc ggaggtcgag gtgcaactgg atcagatggt aggtgccgcg 122760
gtgcacccga ggctgacgga tgtcgtgttt atccgtcagt gtgaggatgg tctgcggcga 122820
gccgctgtac ttgtccagct cgtccggcgt tttcaggagg agactgtcgt cgtcggtact 122880
ggcgacgccc atcatggtcg tggtggtagt ggtggcgagg aaagtgagcg gcggcgccga 122940
cagagctcgg cgttggcggc ggcattttcc gctgtgtcgg ctgctattgc tgccaacgcc 123000
accgccgccg cctcgtctgg ctcgtggccg gcgggcccga ttccgaaggt tggggtcgac 123060
gcgtggcatg cttggtgtct gcgggcgcga gagggccggc tcagccttta aatatgcagg 123120
tcgcggattt gttatcgggt gaaacgtcac acaccgtgaa gacgacctgt tcgcggatga 123180
ggtcatccag ctgtcgcagc atgacgaaaa gcgccgacag ccgcgcgatc tcgtcgtcgg 123240
gcgacacgtg ctgcggccgc gcgggcgtgc gcggctcgcc gacgctgcgc tcgcggtcca 123300
gccgcatcag cagctcctgg cacttgacga gcagcatgga gctgtcctct agcgccaact 123360
tgcgcacgta ggtcatggtc agctccgagg ctaggttggc caccatggac atggagaggc 123420
aggcggtctt catgtcgatc agcaggtgct ggtcgatgac cggatcgggg atggtgaagg 123480
tggcgtcgcg aaaagtaatg gtctgcagct gctgcacggc agcctttacc tcctcgtacg 123540
aacggtcgag cgagaagagg cccatgatga gtagtcgctg gttgatttcc agcgccagtg 123600
gcatgggtac gatccagggc agcaccagct cccactggcc cagcgtcagc aggttctcgc 123660
gcgccagcgg tccgtggaag agcggcggca gcacgcatag cgcgtcgccc ttctcccaag 123720
tcacgggtcc cgtgttgagg acggtgtaga gcagtccgtg cgtgggtacg tgtaggagga 123780
tctggttgcc ttctacgcgc cgcatcaacg tcagcgtcat attgcgcagc aggccgcgca 123840
gtcgtacgta gccgcgggtg tgatctacga actggtgtag gcccagctgg tagtgcttga 123900
tgagatgtag acgttgcgga atgggcacaa cggccgctac tagcttggtc agtttgccta 123960
cgtcggcgat gctgagcttg tggtcgaaag tgcagaagat gttggcctcc atggccgcca 124020
tagcggcggt gaaatcctgg ccgcgacgga ggagaggcag agacgaacaa cgtctgcacc 124080
gggcgcggcg tcagagcgag cgtggcgcgt ccgggcccgc gtttgcgtct aggtgactcg 124140
ccgctaacct gcggtcgtcg ccgtcctcct caccggacgg cctcacgagt taaataacat 124200
ggattgctgc agcgggatga tttcgcctac gacgtagtta ccaaagtgcg tttcggacgt 124260
agcaaaagcc ccggcgccac ccttgagttt ggtctccatc agcgccagcg tggtggtgct 124320
gaggatcggt agcgcttcct gcgtcagacg gcacgggttt tcgatgagtt gttccgtgcc 124380
ttcgacgcag acgtactgcg tgtccgtgtc gccgcggatg cagtccttgg cgcgtagcag 124440
gtactcgtcg atggttttga agagcgtttt gttggccgcg ataatctctt ctgtgttaaa 124500
gtactgcgcg caagggctgt agaatttgga gttgtagcct agacgttcgc gatgtcgggt 124560
gttgtagagt acgtcgctca gacagccggc ttgcgaggcc caggggttgt gtgtggccgc 124620
gaaagtctgt gcgtccgctt cgcgatggtc gtagatggcc ttggtggcgg cctccgtgtc 124680
gtacggatcg acggccagca tgcaggaggc acgcccgcgc gggttgttgg ggatcttaaa 124740
gtaattaacg tccatcgtca ccggcgtaag gattagttcg cacgcggcct tttgtccgtg 124800
caccgtggcg gcggcattgc gctcggacat gctgccgaac gtcagcatag agatggtctc 124860
cgtgtctaac agttgcggcc gttctacgcc ggccgcgtgc cggatccagc ggtccacctc 124920
gtcgtgccgg tacacgttca tagggaagac gcgaaagagg tcctgcacgc ggacgcccat 124980
gtcggttcgc acgcggttta cgtaggctac gcaggtattt gacgtgtaac ccagacccat 125040
gtctacggtg ttaatgttct gcgtgacgtg gtacgtagtg ctgatgtcgc gttcctcctt 125100
ggtcacgata gggttgttga tgataactga cgtgcatgat ttgccgctgt agagcagcat 125160
gtccacctcg aaggtgtcgg tgcgtacggc cgtgagtgcg aatcccgggt ggatgtgcgc 125220
cttggtctgc agcaccagtg aaactggtga gattttgtat aacatggcgg ccagcgtcat 125280
gactgagtgc aacacgttgg gacaggtggc cgagtaacgc gaaaagggcg agcgcagcca 125340
gttgtggtac tcgtgcgcga aggctgtggg tagcgggaaa ccaccgtcgt gacggtgata 125400
gtgcgggaac tcggtcacgt agcgtttaat gtcgtcgctc aacgccgcgc agatggtggg 125460
gtttgagtag aaacggtgga aaggtacggg taggctgtac tcgatcaacg tcttaggcgc 125520
cgtcacgacg cagcagccgt tgtaaagcac gtgctgacgt gagataaagt ccggcaggcc 125580
ctgacgctgc gcgtggtcca gaggcgcgcg cacttcgagc accttgacgt gctcgcccac 125640
gaattgcacg gccaaaaaca gttcacgaca ggcctgcagc agcggcgtat gtgcgtcggt 125700
ggcgacgtcc tccaccagct cggtcagcat ctcgcctacg gcttgacgtt gcgccgctat 125760
cgagtcttcg ggggtgacac cgcttgtgct ctctttcgac gtcgtacctg acgtggagac 125820
cgcggtggcg gccggcatca ggagaaacgc cggtcggtaa aagaggtcta ctagcagcgt 125880
cttgaggttg agtcccaggc cgcaggcccg gttgttggtc atggcgggca tgaggcagag 125940
ataaaagacc ttttgtaacg tccattcgtc gtcggtggca cggtaatcgt ccacaaacag 126000
cggctcgtcg gcatccatgg cgcccaaacg cggtacgtcc gaaacgccgt ggtgtcgcgc 126060
ctcgatgttg gccgggttca acggttgccg gtcggccact acctgtacgc cttccatgtt 126120
acgcggcagg tgcgtaacga aggggggcca cagccggtgg tcgtgcagcg cgttcacgta 126180
agccgatagc ggttcctcag ccagttgacc gttgttaagt cccggcagcg ctgagatgcg 126240
cgttaccaga cgcagcacgg cgaccagatt gcggtagtga aagagcaact gcggtggtag 126300
ggcgccatca gccaggtgtt cggcgatcaa cgtcaccagc gcgtagctgt gcgcaaaaac 126360
cagcagctga cgtgtgtgaa acatgttgac gatacaacgt gctacgaaag tgcggattag 126420
caaaaaagcg tcgacgttgc cgtgtaccag cacgtcgacc aggtagcaaa gctcggggta 126480
attggggctt gtcacggtgg ttttgaaaag tcgcaacgtc tcttcgtagt cgggtggtgg 126540
ccgcagtcgc atgtgttcca tgatctccca ggtgcgcagt tcgtggaagg ggcccggtgc 126600
cagtccatct ggcaaattac cgatgacgat acgcggtgta cacagcgcca ccgtttcgct 126660
gttttcctgg cagtgcgtaa agtcgaagaa ggggtgcagc tcggtgtaga gcgtgatgtt 126720
gcccaccttg tagaagtcgg tgaccacaaa gtcctgcttc atttcgttca ccgtgcgcgg 126780
gacctcgcgt cgtacgcggt aaaaatgcgg tatgcggcgc gccgcaccgc ccatgggttc 126840
ctgctgaaaa cgacactcga gcagtcgttg catggcgggt tccgagggcg gtccgcgttc 126900
cgtgaaggtc tgtagacagg gcgcgggctc gtgcagcacc gggtggcaca gcgtcttgag 126960
cgcgtccaca aagtctattt tttgtacggc acggtcccgg tttagcaggt aggccgtggt 127020
gggcaacgcg ttgcgaacgg tgtcgttaag cttaactttg ctttccaccg tggtgtaacc 127080
gcgatcctcg ggcagataca gccctacggg gaagaaaaac gtcaggtcca cgttacgttc 127140
tagcggatct ttggtatcgg tgtttttgta gacgcgccgc aagttttcca taatcaccgt 127200
tttttcgccc agtcggatca cgtccatgct cagcggcgtt aagctgtgcg ccccggcctg 127260
cgaaagcgag tcgttgggca aatgcggttg gcccgaagtc agatgagcct tgtacgagtt 127320
gaaatcggcc aggatcgagt gataggatat ggcagtgacg gcattttcgg gactgagtac 127380
aaaattgccg taggtggccg gcgccgagac cgtttctttg gtgatgtggc ttgagagcag 127440
cgacatgatg atctgcataa cgttggccgt gcttaccatc acgccgctga tcttggcccc 127500
cgagctcgtg gtgtacgtgg tggggttgtc taggatgcta tcggtggccg cttcggccag 127560
acgcgtgagg aacttgagca catagtcgcg atcgcgcgtg cgattcagca aaaagagcgt 127620
ggccagcatt ttggccttga agctctgcaa gatgttgctt cgctggatgc ggttcagtgc 127680
ctgtcgcgcc agtgtggcgt tttctaccag cgtctgcacc acaaagtacg gcggcgcctt 127740
gcgtagcagt gtctgtaaaa agctgtgaat caagccgcgc tccatggcgt cggccgtgtt 127800
tttaagcgcg cgcagcaccg tgtgcatggc ttccacgttg aggatcttgt ccaagatggt 127860
gccctcgaat gtctcgcgca gatacgtgag gcaggctgcg ctgagctcga aggggatggt 127920
gatgggggat ttttcactgt atttggtgac cataatggtg gtctgacgac tagtgggcaa 127980
accggcgccg ctggccacac gcggcacctg cacgtggaac agcattttgc ccgtagtcag 128040
tttattgagg tcgtggaact tgatggcgtg cgccgccgcg gccaagccgc tggtcaaaaa 128100
ataaacccat tccaggcgat tgcagaaggt gccgaagatg gcttcgaagt gaatattgta 128160
acgctcgggg tcatcgccgt agtagatgcg taaggcctca aacatctcct cgccggcgct 128220
ggtcttgacg tgcgtcagaa agtcagtggg aatgcctact ttaggcagga gctcgagcgc 128280
cgaccagttc tccatcgcgg cggcggcgtg agcgcgaggc gtcggagctc ggggaaagca 128340
gcgcgacccg gagaatggcc ggcgctgcgc cgcgccgcct cggctgtgac gctctaatag 128400
tcgttggcgg ctccgctatg ccgcgccggg ttttacacgt ccccgtgcac gttcgcgcct 128460
gcaacctcac ccaagagcta tcgacgggcg aggacgcccg cttttgtcgt ccgcgacccg 128520
ttaacgtcga acgggtgcgc gctgtttttg cggctctcta ccgtgcctgt ccgatacacg 128580
tgaggaccga gcccgagcgt gtcaagctgg tactgggtcg tctgttactg ggacccgtgg 128640
ccgtaccctg tttttgcgac ggtgaagtgg agggccacgg tgaacatctg gtacctacga 128700
cgcagttttg tcgcgggccg ctgctctacg tgcaccgacg ttgttgttgc ggatccgtga 128760
ccgccgggcg cgcgctgtcc taccacgttc tcgaaaacca cgtggccacg catgtgctac 128820
gcggattgct ctcgctgacg gaatggaatc gagaattgcc gagcctcttt tgcgactgtc 128880
ctggcggcgg tggcgcctcg ggaaccgagg aacgctacgc tatggcctgc ctgccgcgcg 128940
acctcagcct gcacctggac gactatcctt acctgatggt ggaaatcgga cgcgtactca 129000
gtgtcagcga ggtagacgac tacgtaaccg ccgtctccgg ctacctgggc gaggccgcgg 129060
cgccgcgcat ccaggttcac tacaagctgc tctttggact caacgtgcgt ccgcaagcgc 129120
cgtgcgcgtt ggacgctaca cgcgactttt ttctgctgga gctgcaaaag ctttggctgg 129180
gcgttgaata tcaccacgaa gtcacgtcgg agtttttcgg tcgcgtactg gctcagctgc 129240
atcgcgaccg cgcccgcgtc atgatggcgc ttcgcttgcc cgagcagacg gtgtgccacc 129300
tgagcacctt cgttctcagt cgcttcaagc gacaggtact gtacttcaag ctacaggtga 129360
gctacggcaa gtgccggact ggtcacgctg acagaagtgg gggagggggg aacggtggaa 129420
atcagggaca ccacaaccta ctgtgttatc gacgccttag cgtcacattt gccgacacag 129480
acacggtgtg gagaaacctt ttctacgttt attacgaact agctcgggat ctggggtccc 129540
atgggacgga ggaccgaccc gtaagccgcg gttacggtgt ttcttgcgct tcgaggacgt 129600
cgcgactgtc accgtcagaa tcgacggtgg tttcggcgaa cggacacgcg ctgtcttcca 129660
ccgcgctccc gacgacgagc gcgggtcaca agctgtcact gccgcgcgac ccggccgcag 129720
atcgcgttcg acgttacgta tgcattatct cgcgtctcat gtacgctcgg tacggggaga 129780
gatggcgtaa acactgtcaa cggcggtcgg agacgggaga agaggaggag gaagagacgc 129840
tggaatcggg ggagactgac gccacgccgc catttgactt tacggggcag cagctgcgcc 129900
gggcctatca ggaacaccga cgtcgtaaac atctagccgt gcagcgttac gcgccgtgcc 129960
gtcgtaagct catcggcggg atggagtttg ccgaggtgac gggcgtgagt ctagaccgca 130020
tcgccgtcaa cgctttcaac accaaccgcg ttatcaatat gaaggctgcg ctctcgtcca 130080
tcgccgcgtc gggtctcggc gtacgcgcgc cgcggcttcc caagaacatg acccacagtt 130140
ttgtgatgta caagcacacc tttaaggagc ccgcttgcac cgtcagcact tttgtttcca 130200
acgacgccgt ctacatcaac tcgctcaacg tcaatattcg cggttcctac cccgagtttc 130260
tgtactcgct gggcgtgtac cggctgcacg ttaatatcga tcactttttt ctgccggccg 130320
tggtgtgcaa cagcaactcc tcgctggacg tgcatgggct ggaggaccag gcggtgattc 130380
gctcggagcg cagcaaggtg tactggacca ccaactttcc gtgcatgatc tcgcatacta 130440
acaacgtcaa cgtgggctgg ttcaaagcgg ctacggccat tgtgccgcgc gtctcgggcg 130500
ccgacctgga agccattctg ctcaaagaac tctcgtgcat caagaacatg cgcgacgtgt 130560
gcatcgatta cggtctgcac cgtgttttca cgcaactaga gctgcgcaat tcgtaccaga 130620
tccccttcct ggccaagcag ttagtgctgt ttctgcgtgc ttgcctgctc aagctgcacg 130680
gtcgagagaa gcggctgcag ttggaccgcc tagtatttga ggcggcacag cggggtctct 130740
ttgactacag caagaacctc acggcgcaca ccaagatcaa gcacacttgt gcgctcatcg 130800
gcagtcgtct agccaacaac gtgcccaaga tcctggcccg gaacaaaaaa gtcaaattgg 130860
atcacctggg ccggaacgcc aacgtgctga cggtgtgtcg gcacgtggaa gcccacaaga 130920
tccctcgcac gcgcctcaaa gtgttagtcg aggtgctggg cgcgttgcag agtatcagcg 130980
gtacgccgca cacgcgcgaa gtgatccacc agacgttgtt tcgattgtgc tcggcggccg 131040
cagccacatc gggcctgtgt tcatcccctc ccccattgtg tgtgtcctca tcttcctccg 131100
tcccttctgt cccaacctcc gtcagcgttg acggcagttc tgaacccacg tcgccgcgag 131160
cgcggtttgc atcacgatga tggaagccgc ggccgctgcc gccgcggcgt ttcgtccgga 131220
ggagcgtccg acgccgggtt ggcacgacgc ggcgttgtta atggacgacg gtacggtgcg 131280
cgagcacgcg tttcgcaacg gaccgctgtc gcaactgatt cgccgtgtgt taccgccgcc 131340
gcccgacgcc gaagacgacg tggtttttgc ttccgagctg tgtttttatt gcagcggtcg 131400
ttttaaccgc aggtcgtccg tcttctccat ctattggcag aagcatagcg atctggtgta 131460
cgcgcttacg ggcattaccc attgcgccaa gttggtggtg gaatgcggtc agttggggag 131520
tagtaggcta cggtggcgcg acggtgatgc gagtggtgag gagcgccggg gagacgacga 131580
cagcagggac gagctgtacg acgtgccggg catttatatg attcgcgtca acgacggcgg 131640
cagcaccggc cccagacacg ttatttggcc gggtaccagc gtgctttggg cgccggacgt 131700
tgtgatcact acggtgcagc gacgaatctc ggcggcgcgc gccctggtga acacgttccg 131760
ccaatatttt tttttgctgg aacggcgctc gcacgaggag ctggttcttt gtccgcccga 131820
gatggaggag cgtctagcgc cgctgttgca gagtgccacg cgcggtgatt cggacatgtt 131880
tgacggtgtg gtggccagcg cttatcaccg tttgcgaatg agtaatattc cgcgttcatc 131940
cgcccgtctg ctggaacact gcgtggggct ggcgggtgct aagaagctgc tcttgctcga 132000
cgtgccgcgt ctggagaact attttctttg tcaagtctgt ctttacgagc tggacgagga 132060
cgagatgggc gaggagatgc tgggcatgtt ggccggaaag cccgaggatg ccgccgtctc 132120
gggcgcaagc ggcggttttc tgctacatcg caagacgatg aagctggccg cctgtctgtg 132180
tttgttgctc aattcgctgc atttgcacca ggaggcgctg gaggccttgg atcctccgcc 132240
gccgcgcgtc gaggagaacg accttgtcaa cgtggtgctg cgccgttatt atcgcagtca 132300
cggcggcgtg caggcgcgga cgctggcggc ggcccgggct ttgttagccg actacgccga 132360
aacgttttcg cccttgggga gttttacgcg cctgggttac gatcgtctcg tttctgccga 132420
tgccggcgtc agtcgccggc acctggtggc tctgctgcgt gcctagctga ccctgaaacg 132480
gatggcgtgt atatcgtcac acaggtaggt ggccatgatg acggcgatga taagatcgtc 132540
cgagatacga ttctggcgct tggccgagta acgcgccgtc gtgccttcgg ccagcgtgac 132600
gcggtgcagg ttctgaatct gctccagaag atactcgatg gggtcgtggc tcagcttgat 132660
ggtgtaggag acgagctctt gcgaggcttt gatgtagccc gagttgaaac gcgagatgaa 132720
ctgttccacg gccagcgcct tgtcgcggcc catgaggtag aagggctgtt cgatgtggtt 132780
ctggtcgggc gtgtggtaga agagcacgcg gatgagcgtg ctgctctgca cgctctgtcg 132840
gatgaggcag gcgatgcgca cggccgccgc ctggttggtg ttgccctcca cggcgatgcg 132900
cagttcgtcc aggtaagggt gcaggctcag caccgagatg atcatgtgcg ccgcgcactc 132960
ggcgatggct acctcagaac tctcggagag gtcgcgcaaa aagaaatgct ctaggccgta 133020
aatgagaaac tggtgtcggt aggcgcctac ggccgccacg cccgtgcccg aggccttgcg 133080
gttggtggtg aaggccgggt ccagatacac gtaaagcgtc ttgccgaaat aatcgtaggc 133140
gttggtgttg agcgtgctgt aacgcaaaat atcgaactct tcgcggctct ggtccgtgat 133200
gagcacggtg ttctgcgaga ttttattggt accgccgatg atctcgtcca tgaaagcgcc 133260
cggcataaac atgttggccg tcttgcgcac ttgcgagttg aggctgatga aggtgggctt 133320
gtgcagtcgg tagcaaggac acgccgtggc gtcgcccttc tccgtgaagc tgtgcaggtg 133380
ctcttcgcac acgtaagaga ccacgttgag catgtcaaag ggcgcattgt taaggcgcgt 133440
caagaaacac gtggagtcac tggtagtgtt ggtggacgat atgaagatga tcttggtggt 133500
attctgggcc aggaacccca gaatggtgtt gaaggcctct ttcttgatga agtgcgcctc 133560
gtccaccagc agcaagtgga agttttgtcc tcggatgctc tgtgtagaga ggagacagaa 133620
aagggactct tatgattacg cacgctcgac tggaagccta cagagtcggg gtggggccgg 133680
acaggtgagc caggtgagcc gccaggtgag gcgggatcgc cgtgtgccaa ccgggctgcg 133740
acctgaaaac cggaaccaat ccgccgacac cggcgccgcg tgacgcgcgc ccataaaaac 133800
gaaagtgtcg tcgtcgcgac ccgccacagc cgccatgaac tcgttgctgg cggaactcaa 133860
ccgactaggg gtcgcgcacg ccactacgga ggatgttttt atctttgtcg accgcctctt 133920
tcaacacttt tccttccttt tccaggccga ggagtcaggc ccgcgccgct tggaactggt 133980
cgcgtccgtg ttcgagcacc tgacggtgga gtgcgttaac gacatcctgg acgcctgcag 134040
tcacccggac gtgaacgtcg cggagacaag caacacctgt cgtccctgcc cttctcctgt 134100
tccctccgcc cccaaaactg tcagcggcgc tcagacgtca tgtgcgacgc ctcgggcgcc 134160
tgtgacatga ggcacgtcca gaacgcgttt accgaggaga tccagttaca ctcgctctac 134220
gcgtgcacgc gctgctttcg cacgcacctg tgtgatctgg gcagcggctg cgcgctcgtc 134280
tccacgctcg agggctccgt ctgcgtcaag acgggcctgg tatacgaggc tctctatccg 134340
gtggcgcgta gccacctgtt ggaacccatc gaggaggccg cactggacga cgtcaacatc 134400
atcagcgccg tgctcagcgg cgtgtacagc tacctcatga cgcacgccgg ccgttacgcc 134460
gacgtgatcc aggaggtggt cgagcgcgac cgcctcaaaa agcaggtgga ggacagtatt 134520
tacttcacct ttaataaggt tttccgttct atgcataacg tcaaccgtat ttcggtgccc 134580
gtcatcagcc aactttttat tcagcttatc atcggtatct actcaaagca gaccaagtac 134640
gacgcgtgtg tcatcaaggt tagtcgtaag aagcgcgagg acgcgcttct gaaacagatg 134700
cgttccgaat atggaaacgc acctgtattc ggatctggcg tttgaagcgc ggttcgctga 134760
cgatgagcaa ttgcctctac acttggtgct cgaccaggag gtgttgagta acgaggaggc 134820
cgagacgctg cgctacgtct actatcgtaa tgtagacagc gctggccgat ccacgggccg 134880
cgctccaggc ggagatgagg acgacgcacc ggcctccgac gacgccgagg acgccgtggg 134940
cggcgatcgc gcttttgacc gcgagcggcg gacttggcag cgggcctgtt ttcgtgtact 135000
accgcgccca ctggagttgc tcgattacct acgtcaaagc ggtctcactg tgacgttaga 135060
gaaagagcag cgcgtgcgca tgttctatgc cgtcttcact acgttgggtc tgcgctgccc 135120
cgataatcgg ctctcaggcg cgcagacgct acacctgaga ctggtctggc ccgacggcag 135180
ctatcgtgac tgggagtttt tagcgcgtga cctgttacga gaagaaatgg aagcgaataa 135240
gcgcgaccgg cagcaccagt tggccacgac cacgaatcac cgtcggcggg gcggactgcg 135300
taataactta gacaatgggt cggatcgccg tttgcccgaa gcggctgtgg cttctctgga 135360
gacggccgtc agtactccat tttttgaaat tccgaacgga gcaggaacct cctccgcgaa 135420
cggcgacggc agattcagta acctggagca gcgggtagcg cgtttgttgc gcggcgacga 135480
ggaattcatc tatcacgcgg gtccattgga gccgccttcc aagatacgcg gtcatgagtt 135540
ggtgcagctg cgcctggacg taaatccaga cctcatgtac gccaccgatc cgcacgaccg 135600
cgacgaggtc gcgcgtacgg acgagtggaa gggtgccggt gtctcgcgtc ttcgcgaggt 135660
ctgggatgtg cagcatcgcg tgcgcctccg tgtgctgtgg tacgtcaatt ccttttggcg 135720
cagtcgcgag ctgagctacg atgaccacga agtcgaacta taccgggcgt tggacgctta 135780
tcgggcgcgc atcgccgtcg agtacgtgct gattcgcgcc gtgcgcgacg agatctacgc 135840
tgtactacga cgggacggcg gcgcgttgcc acagcgtttc gcctgccacg tgtcacggaa 135900
catgtcctgg cgcgttgttt gggaactttg ccgtcatgcc ttggcgctct ggatggattg 135960
ggcggacgtg cgtagctgta ttattaaggc gctaacgcct cgtctgagcc ggggtgccgc 136020
cgctgccgct cagcgagctc gtcgccagcg cgagcgctcg gcgcccaaac cgcaggagct 136080
gcttttcggg ccgcggaacg agagcggtcc gcccgccgaa cagacttggt acgctgacgt 136140
ggtgcgctgc gttcgcgcgc aagtggattt gggcgtggaa gtgcgcgcgg cgcgttgtcc 136200
tcgcaccggg ctttggatcg tccgtgatcg ccgcggacgc ctgcgacgtt ggctctcgca 136260
gcccgaggtg tgcgtgctgt acgtcacgcc agacttggac ttttactggg tgctgccggg 136320
cggctttgcc gtctcttcgc gcgtcactct tcatggcttg gcgcagcggg ctttgcgaga 136380
ccgattccag aactttgaag cagttcttgc aagaggaatg catgtggaag ctggtcggca 136440
agagccggaa acaccgcgag tatcgggccg tcgcttgccg ttcgacgatc tttagtccgg 136500
aggacgacag ctcgtgtatc ttatgccagt tgctgttgct ctaccgcgac ggcgaatgga 136560
tcatctgttt ttgctgcaac ggccgttatc aaggccacta tggcgtgaac cacgtacatc 136620
ggcgtcgtcg acgcatctgt catctaccta ccttgtacca actgagcttc ggaggtcctt 136680
tgggtccagc cagcatcgat ttcttgccaa gctttagcca ggtgaccagc agtatgacgt 136740
gcgatggtat tacgcccgac gtgatttacg aggtctgcat gttggtgccc caggatgaag 136800
ccaagcgtat cctggtcaag ggtcacggtg ccatggacct gacctgtcag aaggcagtga 136860
cgctaggcgg cgccggcgcc tggttgctgc cgcgtcccga aggctacacg cttttctttt 136920
acattctgtg ttacgacctg tttacctcat gcggcaatcg gtgcgatatc ccttccatga 136980
cgcgcctcat ggcggcggcc acggcctgcg ggcaggcggg ttgcagcttt tgcacggatc 137040
acgagggaca cgtagatccc actggcaatt acgtgggttg cacccccgat atgggccgct 137100
gtctttgtta cgtgccctgt gggcccatga cgcagtcgct catccacaac gaggaacccg 137160
cgactttttt ctgtgagagc gatgacgcca agtacctatg cgccgtaggt tctaagaccg 137220
cggcgcaggt cacactggga gacggcctgg attatcacat cggtgttaag gattctgagg 137280
gccgatggct gcccgtcaag accgatgtgt gggacctggt caaggtagag gaacctgtgt 137340
cacgtatgat agtgtgttcc tgtccggtgc ttaagaacct agtgcactaa cggggtctga 137400
cagttcacgg ggagaagaaa caagaaacaa caaaaaaaag gaggacatgg actcgccacg 137460
gtttgtggca aggcgtatgt tatcatcatg gagctactca cgttggtgtt gtagcaactg 137520
gcaaaaagcg ccgtgctctt ggcgccgcgg tggtcgatgc tgatcacgtt gtccttgttc 137580
tcgaccacgt agtcgcgcgc gaaggtgtgg cggcagcgga actcgacctc tttgagcaca 137640
aactgcgaca cgtgcttttg gtgcgccacg tagccgatgc tgatgccgat catgtgctta 137700
agcagaaacg agataatggg gatgatgaac caagtcttgc cgtgacgtcg cggcaccagg 137760
aacacggtgg ctttctgctt aaagatgtcg atggaggtct gcgagaggaa gtcgatctgg 137820
aaggcgtgga tgaggtactg cagcacgcga ttggccagca cggggatctt ggtcacggct 137880
ataaaaaaga tgacgtgtat caataaattc ttttgaaacg gttcgagtcg gatggctttt 137940
gcgtcgccct cgacggcggt actgaagccg ccgtcgagcc actttttaaa gtcggtcatg 138000
aagttgttga tctgctgaaa ctgcggatcg cggtagagct cggtcaacgc gtccagcttc 138060
tggtaggagg cgcgctgctc ctcggagcac gggcgaaacg tcagtttatc gagcgcgctc 138120
ttgaggcgct cgtgaaacag cagctcgcgc tggctttcct cgggcgagtt gtagtcgcgg 138180
tggcggccgc agaaggccat gagcggcagg aaggcctcgt tgcacgagtg ggccagcccg 138240
agttcggggt gcatcatctg gtagcgcttg cggcacagcg tcgccacatt ggtgaaggcc 138300
gtggagatgc aggaggtggg gtggctcttg cgcttctgca gctccgcgta gcgctcctgg 138360
atcttggcgg ccgagtctcc gcgcaacatg atggcggcgg cggtggtgcg agcggaggtt 138420
aggcggcagc ggcgagagga gaggaaaaag atggcggccg cgaggacgac ggaggatcca 138480
cccgaaaacc acgttgttgc ggacgtggct cgtgggacgg gcgccgtcac tcgttcgtct 138540
tcgtcgtccc tagtggtgtc gtcttcctcg gcgtcaggct cggacgaatc ttcctccgcc 138600
tctcctctca gtttccccgt ctcctccccc tcaactgccg tcaggtctcc ggggtccgcc 138660
ggggtttcaa cgtccctgtg ctcggtggaa cggatggtcg agctgtcggc gcagtctccg 138720
gccgccgatt tctcggtctc cgaggcttgg cgcttcgagg aggccgtaaa tatggcgctg 138780
gtggcctgcg aggccgtgtc accttacgat cgctttcgcc taattgaaac gcccgacgag 138840
aatttcttgt tggtcaccaa cgtaattccg cgcgaatcgg ccgaggtgcc ggtgttggat 138900
agcagtagca gcggtggcga tagcgggccg gaggacaaaa agaaaaacgt cgggaataaa 138960
accgcggggg aaaagaacgg cggtgggtct cgggccaaac gccgtcgtag acgacgcgct 139020
ccgaaaaacg acgccgccac gccgtctttt ctacgtcgac acgacgtgct ggagcgtttc 139080
gcggccgcgg ctaagccttt gccgtcgctt tgtgtgcgtg attatgcgtt acgcaatgct 139140
gaccgtgtta cctacgacgg cgaattaatc tacggcagtt acctgttgta tcgcaaggct 139200
cacgtggagc tgtcactctc cagcaacaag gtgcaacacg tggaagccgt gctgcgacag 139260
gtgtacacgc cgggcttgtt agatcatcac aacgtgtgcg acgtggaggc cctgctgtgg 139320
ctgctgtact gtggaccgcg cagcttttgc gcgcgtgaca cttgtttcgg tcgcgaaaag 139380
aacggttgtc ctttccccgc gttgttgccc aaactctttt acgaacccgt gcgggactat 139440
atgacctaca tgaatctggc tgagctgtac gtctttgttt ggtatcgcgg ctacgaattc 139500
cctgcgccga cgccgcaggc gacgacggcg ggtggtggtg gtggtagtgg tggcggcggc 139560
ggggccggcg cttgtgcggt cgagacgagc gcgtcagcag gccgggtcga tgacgccggc 139620
gacgaggtgc atttgccttt aaagcccgtc tcgctggacc gtctcagaga ggtgttgcag 139680
gcggtgcgcg gccgcttctc ggggcgcgag gtgcccgcct ggccggcctc gtcgcgcacc 139740
tgtttgttgt gcgcgctcta cagtcagaac cgtctctgtt tagatctcgc gcgtgacgag 139800
gcgcggaccg tgagttatag ccccatcgtt atccaagact gcgccgcggc tgtcaccgac 139860
gtcactttga gccacatctt gcccggccag agcaccgtct cgcttttccc cgtctaccac 139920
gtcggcaagt tgctggacgc tctctcgctg aacgacgcgg gtctcatcac gttgaatcta 139980
tgacgtcggt caacaaacag ctcttaaagg acgtgatgcg cgtcgacctt gagcgacagc 140040
agcatcagtt tctgcggcgt acctacggac cgcagcaccg gctcaccacg cagcaggctt 140100
tgacggtgat gcgtgtggcc gctcgggaac agacccgata cagtcagcga acgacgcagt 140160
gcgtggccgc acacctgttg gagcaacggg cggccgtgca gcaagagttg caacgcgccc 140220
gacagctgca atccggtaac gtggacgacg cgctggactc tttaaccgag ctgaaggaca 140280
cggtagacga tgtgagagcc accttggtgg actcggtttc ggcgacgtgc gatttggacc 140340
tggaggtcga cgacgccgtc taacaggtat agcaatctcc gtcacgcctc tgttcagatt 140400
ttattaaaaa aaaaacacaa cataacgaca gtgtcggtgt ggtagctagt gcagccttag 140460
gaacagggaa gactgtcgcc actatgtcct ccgcacttcg gtctcgggct cgctcggcct 140520
cgctcggaac gacgactcag ggctgggatc cgccgccatt gcgtcgtccc agcagggcgc 140580
gccggcgcca gtggatgcgc gaagctgcgc aggccgccgc tcaagccgcg gtgcaggccg 140640
cgcaggccgc cgccgctcag gtcgcccagg ctcacgttga tgaaaacgag gtcgtggatc 140700
tgatggccga cgaggccggc ggcggcgtca ccactttgac caccctgagt tccgtcagca 140760
caaccaccgt gcttggacac gcgacttttt ccgcatgcgt tcgaagtgac gtgatgcgtg 140820
acggagaaaa agaggacgcg gcttcggaca aggagaacct gcgtcggccc gtagtgccgt 140880
ccacgtcgtc tcgcggcagc gccgccagcg gcgacggtta ccacggcttg cgctgccgcg 140940
aaacttcggc catgtggtcg ttcgagtacg atcgcgacgg cgacgtgacc agcgtacgcc 141000
gcgctctctt caccggcggc agcgacccct cggacagcgt gagcggcgtc cgcggtggac 141060
gcaaacgccc gttgcgtccg ccgttggtgt cgctggcccg caccccgctg tgccgacgtc 141120
gtgtgggcgg tgtggacgcg gtgctcgaag aaaacgacgt ggagctgcgc gcggaaagtc 141180
aggacagcgc cgtggcatcg ggcccgggcc gcattccgca gccgctcagc ggtagttccg 141240
gggaggaatc cgccacggcg gtggaggccg actccacgtc acacgacgac gtgcattgca 141300
cctgttccaa cgaccagatc atcaccacgt ccatccgcgg ccttacgtgc gacccgcgta 141360
tgttcttgcg ccttacgcat cccgagctct gcgagctctc tatctcctac ctgctggtct 141420
acgtgcccaa agaggacgat ttttgccaca agatttgtta tgccgtggac atgagcgacg 141480
agagctaccg cctgggccag ggctccttcg gcgaggtctg gccgctcgat cgctatcgcg 141540
tggtcaaggt ggcgcgtaag cacagcgaga cggtgctcac ggtctggatg tcgggcctga 141600
tccgcacgcg cgccgctggc gagcaacagc agccgccgtc gctggtgggc acgggcgtgc 141660
accgcggtct gctcacggcc acgggctgct gtctgctgca caacgtcacg gtacatcgac 141720
gtttccacac agacatgttt catcacgacc agtggaagct ggcgtgcatc gacagctacc 141780
gacgtgcctt ttgcacgttg gccgacgcta tcaaatttct caatcaccag tgtcgtgtat 141840
gccactttga cattacaccc atgaacgtgc tcatcgacgt gaacccgcac aaccccagcg 141900
agatcgtgcg cgccgcgctg tgcgattaca gcctcagcga gccctatccg gattacaacg 141960
agcgctgtgt ggccgtcttt caggagacgg gtacggcgcg ccgcatcccc aactgctcgc 142020
accgtctgcg cgaatgttac caccctgctt tccgacccat gccgctgcag aagctgctca 142080
tctgcgaccc gcacgcgcgt ttccccgtag ccggcctacg gcgttattgc atgtcggagc 142140
tgtcggcgct gggtaacgtg ctgggctttt gcctcatgcg gctgttggac cggcgcggtc 142200
tggacgaggt gcgcatgggc acggaggcgt tgctctttaa gcacgccggc gcggcctgcc 142260
gcgcgttgga gaacggtaag ctcacgcact gctccgacgc ctgtctgctc attctggcgg 142320
cgcaaatgag ctacggcgcc tgtctcctgg gcgagcatgg cgccgcgctg gtgtcgcaca 142380
cgctgcgctt tgtggaggcc aagatgtcct cgtgtcgcgt acgcgccttt cgccgcttct 142440
accacgaatg ctcgcagacc atgctgcacg aatacgtcag aaagaacgtg gagcgtctgt 142500
tggccacgag cgacgggctg tatttatata acgcctttcg gcgcaccacc agcataatct 142560
gcgaggagga ccttgacggt gactgccgcc aactgttccc cgagtaaccg ggacgcggaa 142620
cgtgacggtt gctgagggga aaggcaacag agaaggtaca aacccaccgg cggggaaaat 142680
accgaggcgc cgccatcatc atgtggggcg tctcgagttt ggactacgac gacgatgagg 142740
agctcacccg gctgctggcg gtttgggacg atgagcccct cagtctgttt ctcatgaaca 142800
cctttttgct gcaccaggag ggcttccgta atctgccctt tacggtgctg cgtctgtctt 142860
acgcctaccg catcttcgcc aagatgctgc gggcccacgg tacgccagta gccgaggact 142920
ttatgacgcg cgtggccgcg ctggctcgcg acgagggtct gcgcgacatt ttgggtcagc 142980
ggcacgccgc cgaagcttcg cgcgccgaga tcgccgaggc cctggagcgc gtggccgagc 143040
ggtgcgacga ccggcacggc ggctcggacg actacgtgtg gctcagccgg ttgctggatt 143100
tagcgcccaa ctatcggcag gtcgagctct tccagttgct ggaaaaggaa tcgcgcggac 143160
agtcgcgcaa ctcggtgtgg catctgttgc gtatggacac ggtctcggcc accaagttct 143220
acgaggcctt cgtcagcggc tgtctgccgg gcgccgcggc ggcggacggt tcgggtggcg 143280
gcggctcgca ctacacgggt tcgcgcgccg gcgtctcgcc gggcatccag ttcggtatca 143340
aacacgaggg cttagtcaaa acgctggtgg aatgttacgt gatgcacgga cgcgagccgg 143400
tgcgcgacgg cctcggtctg ctcatcgacc ccacgtcggg gctgctgggc gcttccatgg 143460
acctgtgctt cggcgtgctc aagcagggta gcggtcgcac cttgctggtg gaaccgtgtg 143520
cgcgcgtcta cgagatcaag tgccgctaca aatatttgcg caaaaaggag gacccctttg 143580
tgcagaacgt gctgcggagg cacgacgcgg cggccgtggc ctcgctgttg cagtcacacc 143640
cggtgccggg cgtggagttt cgcggtgaac gcgagacccc gtcggcacgc gagtttctgc 143700
tttcgcacga cgcggcgctc ttcagggcca cgctcaagcg cgcgcgcccg ctcaagccgc 143760
ccgaaccgct gcgcgagtac ctggccgatc tgctgtatct caataaggcc gagtgttcgg 143820
aagtgatcgt gtttgacgcc aagcacctga gtgacgacaa cagcgacggg gacgccacga 143880
tcactattaa cgcgagtctc ggcctagccg cgggcgacgg cgctggcggc ggcgctgatc 143940
accacctgcg gggcagcccg ggcgattcgc cgccgccgat acctttcgag gacgaaaaca 144000
cgcccgagct gctgggccgg ctcaacgtgt acgaggtagc gcgcttttca ctgccggctt 144060
ttgtcaatcc gcgtcaccag tattactttc agatgctcat tcagcagtac gtgctcagcc 144120
aatactatat aaagaagcat ccggacccgg agcggatcga tttccgcgac ctgcctaccg 144180
tctacctggt ctcggccatc ttccgcgagc gcgaggaaag cgaactgggc tgcgagttgc 144240
tggccggcgg tcgcgttttc cactgcgacc acatcccgct cctgctcatc gtcacgcccg 144300
tggtctttga ccctcagttt acgcgccatg ccgtctctac cgtgctagac cgttggagtc 144360
gcgacctgtc ccgcaagacg aacctaccga tatgggtgcc gaactctgca aacgaatatg 144420
ttgtgagttc ggtaccacgc ccggtgagcc cctgaaagat gctctgggtc gccaggtgtc 144480
tctacgctcc tacgacaaca tccctccgac ttcctcctcg gacgaagggg aggacgatga 144540
cgacggggag gatgacgata acgaggagcg gcaacagaag ctgcggctct gcggtagtgg 144600
ctgcggggga aacgacagta gtagcggcag ccaccgcgag gccacccacg acggctccaa 144660
gaaaaacgcg gtgcgctcga cgtttcgcga ggacaaggct ccgaaaccga gcaagcagtc 144720
aaaaaagaaa aagaaaccct caaaacatca ccaccatcag caaagctcca ttatgcagga 144780
gacggacgac ctagacgaag aggacacctc aatttacctg tccccgcccc cggtcccccc 144840
cgtccaggtg gtggctaagc gactgccgcg gcccgacaca cccaggactc cgcgccaaaa 144900
gaagatttca caacgtccac ccacccccgg gacaaaaaag cccgccgcct ccttgccctt 144960
ttaactcata aactttcagg tctcgcgtac gattcgcgag tcgggaatgg gacacccgtg 145020
ggtgtttctc cgtgtgtata ttattttttt tttttgtgtg tgtttgcgcc cccgtgtgtc 145080
taatgtgctg tttgaaacac gtaaagtagc tggtggaaga acagataaac ctttaataaa 145140
aaaaaaagta tgtgctcccg acccacggtc tgcgtgtctc ttttttatgt ccatgtctcc 145200
aagtctggtg cgggtggcgg cggggttaag cgtcctcgaa gtcttcatca tcgtcgtcgt 145260
cctcttcttc gcggaggcga cggctttcca agctgtcgtg gtgactgagc acagcgactt 145320
cttcgccgga ggctgtggcc agcgcctggt acttgacact gccgctaccg cgtccgcgaa 145380
agtagcggac ggcgcgacac gtcgtaaaca tggcccatat gaaaaagagc atgccgaacg 145440
accagctgat gccggtgcgg tattcgttgc tgaggaaggt atcgtactgc acgatggggt 145500
agatgaggcc gcagagtcca aagaaggcgc ccaggtggta gccgaattgc accttgacgt 145560
attgaaaaaa gacggcctcg atcagtaaaa agtagatgat ggagatgata gcgtagacca 145620
cgaagacggc taacaccatg tggcctgtac gcacgaaaaa gttgtttccg aagccgtagc 145680
acagggccat ggctaccacg gtggtgttga aaccaagcgc tacctctacc aggttgacga 145740
tgagcgtgcg gaactgcacc gtacctttga gcttggggtg cagacgcgag aagaaaaaga 145800
gtgagcgttt gtagctgcgg tactgcgtga ccatgctcac gttgaaaatg gtcaggcaga 145860
aaaagtgcac ggcggccatg aaggcgatca tgctgggcag ccgaaatgac atggtcagtg 145920
tgaatagttg gaacgtgtcc atgctgagaa tgaagaggaa ggctgtgagg ctgtcgccca 145980
tgtacgaaat gtcgcgtgtc gactggttta ggctcatgcc tttgtccttg cgcatgctga 146040
tcttgatcca gcataccagg tagtagatgg tcacggctaa aaagacgagc tgcatgaaca 146100
cggcgtagca caccaactgc accgagtcta agaaaagcat aggcgtgtgc aggtgcatta 146160
cgttgtaggc cgacatgttg agcctttcaa agtccacgac gtgatagtag acgcaggggt 146220
agcccaggtg cggaaaattg ctcagcacta gatgcacgct gacgttgaca aaagtcagca 146280
ccatgaaaac gatagaagcg ctccatgtcc gtgtattcac cttatccacg tgcgaggggg 146340
ccatggcgat agcggcggcc cgctcgctcg ggaggcgatg ggggcgcgcc gatgacgaca 146400
ggctcgcggg tcgttaaata ctacgatggg agccgccgcg gctcacgacg cggtttgagc 146460
acgtccgggc ggtcggtgaa aaaagacccc gcgggccttc gcgactctct tctgtccgag 146520
gatgaccgct cagccgccgc tgcaccaccg ccaccacccg tacaccctgt tcgggaccag 146580
ctgtcatctc agctggtacg gccttctaga ggcctcggtg cctatcgtac aatgtctgtt 146640
tttggatctg ggtggcggcc gtgccgagcc gcggcttcac acgttcgtgg tgcgcggtga 146700
ccgtctaccg ccggctgagg tgcgtgctgt gcatcgcgcc agctagggtg cgctggcctc 146760
ggccgtgact acggacgccg atgagcgtcg gcgcggccta gagcagcgta gcgccgtgtt 146820
ggcgcgcgtg ttgctagaag gcagcgcgtt aatccgcgtg ttggcgcgca ccttcacgcc 146880
ggtgcagatt cagacggacg ctagtggcgt ggagattttg gaggccgcac cggcactggg 146940
cgtggaaacc gcagcgctgt cgaacgcgct tagtcttttc cacgtagcca agctagtggt 147000
catcggctcg tatcccgaag tgcacgagcc gcgtgtggtc acgcataccg cggaacgcgt 147060
ctccgaagag tatggcaccc acgcgcacaa aaaattgcgt cgcggttact acgcctacga 147120
tttggccatg tcgtttcgcg tcggcactca caagtatgtg ctggagcgcg acgacgaggc 147180
cgtcctggca cgcctctttg aggtgcgcga ggtgtgtttt ttgcgcacct gtctgcgtct 147240
ggtcacgcct gtcggtttcg tggccgtggc agtgaccgac gagcagtgtt gtttattgct 147300
gcagtcggcc tggactcacc tttacgacgt gcttttccgt ggtttcgctg ggcagccgcc 147360
gctacgcgac tacctggggc cggacctctt tgagacgggc gccgcccgtt ctttcttttt 147420
tcccggtttc ccgcccgtgc ccgtctacgc ggtccacggt ctgcacacgt taatgcgcga 147480
gacggcgttg gacgcggcgg ctgaggtgct ctcgtggtgc ggcctgcccg acatcgtggg 147540
ctcggccggc aagctggagg tggaaccctg cgcgctctcg ctcggcgtgc ccgaggatga 147600
gtggcaggtc ttcggtaccg aggccggcgg cggcgccgtg cgtctcaatg ccacggcttt 147660
tcgcgagcga ccggccggcg gcgatcgtcg ctggctgttg ccgccgctgc cacgtgacga 147720
cggcgacggt gaaaacaacg tcgtggaagt cagcagcagc accggcggtg cgcacccgcc 147780
gagcgacgac gccactttca ccgtgcacgt tcgcgacgcc acgctacatc gagtgctcat 147840
cgtggatttg gtcgagcgcg tgctggccaa gtgtgtacgc gcgcgcgact tcaatcccta 147900
cgtgcgttat agtcatcgac tccacactta tgcggtttgt gaaaagttta ttgagaatct 147960
gcgttttcgc tcgcgacgcg ctttctggca gatccagagt ctgctgggct acatctccga 148020
gcacgttacg tcagcctgcg cttcggccgg ccttttgtgg gttctgtcgc gcggccaccg 148080
cgagttttat gtctacgacg gctattcggg tcacggaccc gtctcggccg aagtgtgcgt 148140
gcggactgtg gtcgactgtt attggcgcaa actttttggc ggcgacgatc cgggtcccac 148200
ctgtcgtgtt caagagagcg cgcccggcgt gctgttggtc tggggcgacg agcggttggt 148260
gggtcccttc aacttcttct acggcaacgg cggcgccggt ggtagtccgc tccacggggt 148320
ggtgggtggt ttcgcggcgg gacattgcgg tggcgcttgt tgcgcgggct gcgtcgtcac 148380
tcaccgccat tctagcggcg gcggtggtag tggcgtgggc gacgcggacc acgcgagtgg 148440
cggcggtcta gatgccgctg ccgggagtgg tcataacggc ggtagtgatc gggtttctcc 148500
ctccacgccg cccgcggcgt taggtggctg ttgctgcgca gccggtggcg actggctctc 148560
ggccgtgggt catgtcctgg gccggctgcc ggcgctgtta cgggagcgcg tgagcgtgtc 148620
cgagctggaa gccgtgtacc gcgagatcct ctttcgtttc gtggctcgcc gcaacgacgt 148680
ggacttttgg ttactgcgct tccagcccgg tgaaaacgaa gtaaggccgc acgctggggt 148740
gattgactgc gcgcccttcc acggcgtgtg ggccgagcag ggccagatca tcgtacagtc 148800
acgcgatacg gcgttggcgg ccgatatcgg ctacggcgtc tatgtggaca aggcctttgc 148860
catgctcacg gcttgcgtgg aggtctgggc gcgagagtta ttgtcgtcct ccaccgcttc 148920
caccaccgct tgttcttctt cttccgttct ctcctccgcc ttgccgtccg tcacttcgtc 148980
ctcttcgggc acggcgacgg tgtctcctcc gtcttgttct tcttcgtcgg cgacttggct 149040
cgaggagcgc gacgagtggg tgcgctcgct ggcggttgac gcgcaacacg ctgctaagcg 149100
ggtggcttcc gagggcctgc ggtttttccg gctcaacgct taacgagtca cgtaggggaa 149160
ctacgtgggt aagtgacgtg gatactagta aaaaaagtgc gtcaaagctc ttagcgtgtg 149220
acgtggatac tagtaaaagg gacgtcaaag ctcactacgt gttgcgtgtt tttttttttt 149280
ctatgatatg cgtgtctagt tcgcttctca ctcttcctct cctcgttccc agcgcggcgg 149340
cagcttgggg ggtgagggca aattggggta gttggcgttg agcacgtcta gcaggcccag 149400
gcccacgggc caaccgtcca cggtcttgcg ctcggtcagc ttgaggctga acgagtgtgc 149460
ctcgtcctga ccggtaaggc ggaaaaagaa gcgtgctacc agctgcaggc aggtatgccg 149520
cgtctgctgg aagagcacga aggtagcggg cacgtactgc acaatgtgcg gctctttttc 149580
ctcaaagagc aggtagagcg cgctgcagat cagccgcctg gcgctgtggt gcagcagccg 149640
gccgaagctt tcgcgcacgt tcaccgcgtc caggtactgg agcaggtcgt gcaggcactt 149700
gcgcgttaag ttgcaatttt ccacgcacga aataacggta cagagcgcga agtgcagcag 149760
gttgtcggct ttgacgatgc cgcagcggtg tttgagccgc agatccgaga gcctcacctg 149820
cgtgacggcg tcttcggtct cgagcaaaaa cacggcggag tagcctagaa aggccgaggt 149880
gcacagcaac tcgctgcggt actcggccat ggagaccagc agcccgtgct ccgtgtgcag 149940
ccacagcttg tcgccgcgca ccgtaaagtc gagcacttgc ggctccatga tcatcacatt 150000
ctgtctagtg aaatccgtat ggacctccag cacgccgcgg atcatcaggg cctccatttc 150060
gaaatcggcc gacacgctct gggccgcgcc gctcctcgtc tgccgtgatc aagcggcgcg 150120
gcgcggacct ttcaagtgtt cctgggccgc cgctcgaggc agttcccctt tctggcactc 150180
cgcccgccgc ttcgcggctc atttggcgcc gacgcgcctt ctcgcggctg caaatcagct 150240
ccacgtatcg gcaaaacttg ctgtcgtcgt aggcggcggc cacgatctcg ccgaaggaga 150300
gctgcaggta ggcctcgggt acggggtcca gcgtgcccag cgccaggatg tgacacagat 150360
agggcagggt cacgcgctct accgtgtaat tggagtagac gatggcctct tcggcccctt 150420
gatgcgtgac cagacgccgt aggcgaaagg tacggaaata ctcgttttcc cacaactgcg 150480
tgaggaagcg ttccagcgac tcggtgccgg gcacgaactg cgagaagaag ctgttggcca 150540
ccaggcggtt gtcttccacc gccagcggac ggaagggcgc cgcgtcgcgc gccttgcgca 150600
cggcctccaa cacgggcagg tggtagagtt cggcgtcgcg cgcgcccagg ctcatggagt 150660
cctcgcgccg cgaggcgtag cgcgtgagca ggtcgcgcag ttcgcgcacg cgattctccc 150720
aggtctggtt aagcgtgcgc aggtcctgga tctcgtccac ctgcgactgg atctgctcct 150780
ccaggcactt gataacctgc ttcttaaaca ggtcgcggat gtcccgctcg ggcgccgccg 150840
ggccgggtgg cggcggcagc agcccgacgt ggcccgcggg tcctcccacc acggcgccgc 150900
cgggtcccac cacgccgggt ccgcccggac cacgcgcggg tagtagacgg ttttggtcca 150960
ccagcgaggg ggtcaggtcc tgcagaaagg actcgacgct gtcctcgatg ccgatgcgcg 151020
atttgctgtc cgagacgtta agcaaaaact tcataatgga ctttttggcg tcgctgcccc 151080
ggtcgtgctg ctccatcatc tccaccagct tcttgcagtt gagctcgtgg cggctggcgg 151140
tcaccacttt cacaggaaag gtattgagca actggcagat cttttggtgg cggcagagcc 151200
cgtcgtagcg cagaatctcc tcgtgcaggt gtgccaccgg cgtggtgaac agcagcttgt 151260
cgcgctcata agccagcggt tcggccgcca cgtacaagcg gatgtgcttg ccgcgcagct 151320
gcgcctccag ccgctccgag cgcaccttct tgaagacgcg tacctcgggc gcgttggcta 151380
cgcgcacggc gcccaggcgc tcggccacct gcagcagcag cgccaggtta gcctgcagca 151440
ggtcctgcgc cagcgggtgt gtctcggtgg cccgctgcac ggccgcgcgt acaaattgcg 151500
cccgctcggc cgcctcgctc ggcttggtct tcacgtccag cagcggtacc agtcccaccg 151560
ttacgcacca atccacgtag agaccatagt cgtcgttatc ggcgtactga tataaaatgt 151620
cgcggaggcc gcccagcacg cccgtttgca cgctctggcg caacgaggcg ctccacacca 151680
acagatactg ctccaggtcc tcttcgtcca gcgcgcggta gggaaatagc gccgcgtgca 151740
acttccactc ctcggccacg cgccgcaccg tgatggtgtc aaagagcgtt ttgcacactc 151800
cgtagagcag ctgcttgcgc agcacgcacg ggtcgcgcag cacctggtgc atgctttggc 151860
cgcgacacgt ccccagaaag ccgtgcagca accgcaggaa gctcatcgtc tgccccgtgg 151920
ggaaaatgtc gatgacggcc tcgtcatcca cgccgcggcc cacgcccaag tacgacgacg 151980
ccttgatcct caacctctcg tcggccgcca agatcgaacg gatcgtcgac aaggtcaagt 152040
ccctctcgcg cgagcgcttt gcgcccgagg atttttcgtt ccagtggttt cgctccatca 152100
gtcgcgttga acgaacgaca gataacaacc cctctgccgc aactaccgcc gcggcaacga 152160
cgaccgttca ctcctccgcc tcctcttctg ccgccgctgc cgcttcgtcc gaggccggcg 152220
gcacgcgcgt gccctgcgtc gaccgttggc ccttctttcc cttccgcgcg ctgctcgtca 152280
ccggcacggc gggcgccggc aagacttcca gcatccaggt gctggcggcc aatctagatt 152340
gcgtgatcac cggtaccacg gtgatcgccg cgcagaacct cagcgcgatc ctcaaccgca 152400
ctcgctcggc gcaggtcaag accatctacc gcgtcttcgg cttcgtcagc aagcacgtgc 152460
cgctggctga cagcgccgtt agccacgaga cgctggaacg ctaccgcgtg tgcgagccgc 152520
acgaggagac caccatccag cgcctgcaga tcaacgatct gctcgcctac tggccggtca 152580
tcgccgacat cgtggacaaa tgcttaaata tgtgggagcg caaggccgct tcggcctccg 152640
ccgcggccgc agccgccgcc tgcgaggacc tctcggagct gtgcgagagc aatatcatcg 152700
tcatcgacga gtgcggcctt atgctgcgct acatgctgca ggtggtggtg tttttttact 152760
acttttacaa cgccctgggc gacacgcgac tttaccgcga acgccgcgtg ccctgcatca 152820
tctgcgtcgg ttcgcccacg cagaccgagg cgctggagag ccgctacgac cactacacgc 152880
aaaacaagag cgtgcgcaag ggcgttgacg tgctctcggc gctgattcag aacgaggtgc 152940
tcatcaacta ctgcgacatc gccgacaact gggtcatgtt tattcacaac aagcgttgca 153000
ccgacctgga ctttggcgac ctgctcaagt acatggagtt cggtatcccg ctcaaggagg 153060
agcacgtggc ctacgtggat cgcttcgtgc ggccgcccag ctccatccgc aacccctcgt 153120
acgccgccga gatgacgcgg ctttttctct cacacgtcga ggtgcaggct tacttcaagc 153180
ggctgcacga gcagatccgc ctgagcgagc gccaccgtct ctttgatctg cccgtctact 153240
gcgtggtcaa caaccgcgcg taccaggagc tctgcgagct ggccgacccg ctgggcgact 153300
cgccgcagcc cgtcgagctc tggttccgcc agaacttggc gcgcatcatt aactactcgc 153360
agtttgtcga ccacaacctc tccagcgaga tcaccaagga ggcgctgcgc cccgcggccg 153420
acgtcgttgc caccaacaac tcctccgtcc aggctcacgg agggggagga tctgtaatcg 153480
ggagcaccgg cggcaacgac gagacggcgt ttttccagga cgatgatacc accactgcgc 153540
ccgatagccg tgagacgctg ctcaccttgc gcattaccta catcaagggc agttcggtgg 153600
gagtcaactc taaggtgcgg gcctgtgtta tcggatacca gggcacggtc gaacgtttcg 153660
tggacatctt gcaaaaggac acgtttatcg aacgcacgcc ctgcgagcag gcggcctacg 153720
cctactcgtt agtttcgggc ctgctcttct cggccatgta ctacttctac gtgtcgccct 153780
acacgaccga ggagatgttg cgtgagctgg cgcgcgttga gctgcccgac gtgagttcgc 153840
tctgcgccgc tgccgccgcc acggccgccg ctcccgcttg gagcggggga gagaatccga 153900
taaataatca cgtcgacgcg gattcttctc agggcggcca gagcgtgccg gtatctcaac 153960
ggatggaaca tggccaagag gagacccacg acatcccctg cctgtccaac caccatgacg 154020
actcggacgc catcacggac gccgaactca tggatcacac cagtctgtac gcggatccct 154080
tttttctcaa atacgtcaag ccacctagcc tggcgctgct ttctttcgag gagacggtgc 154140
acatgtacac taccttccgc gacatttttc tcaagcgcta ccagctcatg cagcgtctca 154200
cgggcggtcg cttcgccacg ttgccgctcg ttacctacaa tcgccgtaac gtggtgttca 154260
aggccaactg tcagatcagc tcgcagaccg gctccttcgt gggcatgctt tcgcatgtgt 154320
cgccggcgca gacgtacacg ctcgagggct acaccagcga caacgtgctc agtctgccca 154380
gtgaccgcca ccgcatccac cccgaggtgg tgcagcgcgg cctttcgcgg ctggtgctac 154440
gcgatgcgct tgggttcctc tttgtgctcg acgttaacgt ttcgcgcttc gtcgagtcgg 154500
cgcagggcaa gagtctgcac gtgtgcacca ccgtggacta cggcctcact tcgcgcacgg 154560
ccatgaccat cgccaagagt cagggcctgt cgctcgagaa ggtggccgtg gactttgggg 154620
accatcccaa gaacctcaag atgagccaca tctacgtggc catgtcgcga gtcacggacc 154680
ccgaacacct catgatgaac gttaacccgt tgcgactgcc ctatgagaag aacaccgcta 154740
tcacccccta tatctgtcgc gcgctcaaag acaaacgcac cacgcttatt ttttgacaca 154800
acaccgtgta aggaaaacgt gactttattg agcagggtaa aaaccacgta caagaaccac 154860
gttgtctatc cccaaaaaaa cacacaccgt cagggaacac atcgcctata gatagcggca 154920
ctttacataa aaccaccgta cctgcatcac ggtggctcga tacactggaa attcaataaa 154980
aaccaccgtg tctccgtgac ggtacttatc gggtcagcgt cttttgagat ttctgttcgt 155040
aaacttatcc gtttccccgg tccgcggtgt ctcctcgcga ggctgacagt cgacgggtgg 155100
tacctgcaag agaagaaacc cgggtgggag cgacgccgtc gctgggtatc aaccccgcgg 155160
ctgaccgtcg tccggtaaag gaacaacccg tcgtcgcaag ccgggttcga ccaagagaaa 155220
aaacccgggt gcggggggag acgggtcgtc ctttggttgt tcgcggacgg cgtacatgcc 155280
gcgtgggtca gtcgacggcg tcgctccgtg cggtcggtca tcattctgct tcacatatat 155340
gggttgtttg tgtttttttt tataatgaat acgcactgat cctatccgtg actgcgcgtg 155400
tggcagagag gatgccttat aacatgtatt ttgaaaaatt gccaacagct ataatttctc 155460
tcatgtagca gaatagagac cttttgtcgt ctttttgttt gtcattactt gttttccagg 155520
gaattagaga gagggaaccg cgcctccggc ggcggtgccc gcggaccccg gccccttctc 155580
gcgtgcgcgg tgtgactggt tgagcgaatg agcagctagg cttggtggtg ctccgcgtgc 155640
gggggagaag acgattaaca acaaaaaata agtggaagtg gccggtgggt ctttgtccgc 155700
gtgcgcgccc atccgtcgcc gggaccgagc agaaagtgat gtggtggtac attgattttt 155760
tccttgacag gaaagaaaaa aaagagtttt gttttcctat gtgagaggag aaaggtatgt 155820
gaggagatgt tcgatgatcg tatgttacag ttatgctgta aggaagcttt tatcgtgcgt 155880
cctgtttttc atttgatgta tatgacacaa ttgaaaccta tcgataggcg tatatcgagg 155940
attcatcaat tcttagaatc gtcgtctttt tggctaattg gactttgccc atgttggttg 156000
tcattcgtgg cctgaggtca tcgtcgtcca cgacgacgtg tctatagcgt gcggtgtgat 156060
cattgtgtcg agccagagaa agcgcgcctc gcacgacgtt tgcggatcgg ctcgcgggtg 156120
tgtggaattc ctaagaacat aatcagctgg tcgtctttct ttgatgtgtt gttgtcgtcg 156180
aggtcttgct tcgttttctt ttttcttttt agtcgatgga acttttcttc ggtacgggtt 156240
cttgttatgg aagcttgtgt tttcgaacat gaattcgaaa aaataaaaag gcctatcttc 156300
gtttcaaaaa aaggacagat atcaatcttc ttaacttata tcatggtaaa ttcagaatcc 156360
tatggtgtct tattatctct aaagtagtca acattatggt ctaacttgta tttccctgac 156420
gagatatata tgatccttat aacctggcta ctatcatgaa caacaatatc cttacttaca 156480
gtcatcttcg tgagttaatg aagtataata tcggtcatct atcaacttat ctgctatgta 156540
acgtaccctt ttaggtattt tgcgtttctt aacgagtgta cccgcctgtg tgaggcgaaa 156600
ctctgagaag tctaccgagt cgagttacaa gtcactaaaa cacttacacg agttatctat 156660
actaaaatca ctatctatgt tgtttgctta cctaattatt atcctacatg acgaagctac 156720
ctcccaacgt aaggtagggg gagaggagac agaacaataa aaagtaacta atgtttctta 156780
gaacttaccc gctaaggact taccaaacta tattcaccaa aaaacaacag ctacgtgttt 156840
catttgtttt aatctaccga agtaaaaaaa aaaagatgat tagctatcca gaacctactt 156900
acttcttaat gttttaacta aggatgccta tgggattgga aaaaaaatca cagcaacttg 156960
ctactaatca gttgacagcg aagagactca taacaaagat ttctgggtaa tacggttata 157020
ataatgctta tggactaaag gatacttgga aaaaaagaac gggctatgac tatagagatt 157080
cgtcgagata tcaaacttca aataggcggc tatcattcat ggttgtggtg actatatcgt 157140
ggagaaaaaa tgtgatcgtt agttagctag gtgagactta cagctatcca tccgtctagt 157200
ttttcgttgt aatgatgata gtacgtctat ggtggtgatc gattttggtt aacaatttgt 157260
tcgtttaaag gcttaatgta cttatgctac atgatgtatt attctttgat tcatcgttcc 157320
tcctaagggg gtgtatgtat gtatgtacta gtcgtatagt gttcctaaca tcatgactat 157380
tcagactatg gcttcatcta tcgtgtctaa agttcactta ttctactatt actatatata 157440
tgcactacta tgtaactagg atatggtcct ataaggtgtc ttctatcacg gtggcttgtt 157500
tatcgcttgg cggttacgag caagagttca tcacggacca gccgtgaggc agggcacacg 157560
cgggtcggcg gcgatgatgt cccccgcgaa ggggacaacg aaaacaagag gccgccggcc 157620
gcggccacgg atgcgtagcg gttacacaat gtttggttga gcgttttgtt tcatcgtcgt 157680
ggtggttttg ttgttctctg tatatatcgt gtggtggctt tatcgtcatc attattatca 157740
tcattcttgt ttccatcatc acgatgagtt ttctccgttt tcctctcctc cagtggtagt 157800
cgtgtatcat catcaatcat cgtagtgacg tcgttgctgc tgctgctctt gccttcatgg 157860
cggtatttct cttcctcccc cctaacccca tattaactcg tgagtgtgat ggttagagtg 157920
gctgcttgtt ttttttttct tttctctttg gaacaacaaa agaggataaa gatggtcggt 157980
gaatgtatta ttattatcat cattatgata cggtcgcggt cttcttctcc gatgacgaaa 158040
cctgcgcaca tcgaagaaaa gacgagcgcg cgaaccgata gccgtccgtc tgggacgaag 158100
gagaagatga tggggagagg aggagagccc cagaagccag agcgagaagg gagacgacag 158160
acatacgtcg tcaccgtcct ctggaggagg cacggcggcg ctgtttgttg tttggatgct 158220
tgattatatc ctgttctatg gggtagatta ttatcaatag gcttggtttt caaaggtcag 158280
cctgtgtatt gtcgtgtctt tttttttcgt tctcatgatc gcggagacca cacagacgtg 158340
cgcgtctccc aatggctagg cgttcttttt aggtagtaat tttttgatct tttttttttc 158400
ttaacaagtc tggcttgatt tcttttatct atgatcgatt cttctttttc tcgggggttg 158460
catcttccgt gaaagtaaag tgacactact ctaaatggta accatattat ctgttgatta 158520
ggagaaaaaa taattttttc gcacgaaatc gatcctaagt gaggtgattt acttgctatc 158580
acacgaaatg attatctttt gctgctaacg tactgaattt tttaacagaa ttgcttctcc 158640
gtaactattt ccgcagattc agacagattg tcaaaaaaga atacggcaca gaaatagtgg 158700
gtctgtggct tttggttcgt gtacattcgc gtttgcgtgt cgagatttct acggtatgtt 158760
tattcttcct gcgatgatgt agggtccttg gtgtaagtag gatttcgagt atctctctta 158820
gagcgaacaa aataatcaaa aaacaacagc taggaaatcg agggttactc tacgataaag 158880
tgtctctaca aagtgaagaa tgttacgttg tggtggaata ataagactcg cgtgatcgat 158940
gagtgatcga gagcggctcg aaccttcttt aagagctttg tttagtgcaa ctttaaatta 159000
caaggagtag aaagctgaaa tgaatctatg aaggtgctat tctttgaata tcttactttg 159060
tacgcttcac attcgttatt tggatagaga gttgtctaga gaaaatctgt gattctctat 159120
gagtgttatt tttattatcc ttttggggac tacgattttt cttcttgttc tacataccac 159180
tactactcgt aatcacatac atggacgaaa aaaaaattcg tcaggcagta gataccagat 159240
tctccgacgt tacggcgtct tttttttctt ttgagagagt atctgctgag attgtccgtg 159300
gtgtatctag tcgctatttt tgttgttact agtagttttg cacacagttt attcagtata 159360
gtttttcttc ttgccatgat caattaagcc caccaccttt ttttttagag aggaggaatt 159420
tcgtcttgat ctccagccgg agacaacggc ggtggtggtg gtggcgggag agacttcaag 159480
gcaatgaaaa aaaaaatttc gttttgccat caagtggtga cgataacccg tcagattgat 159540
aattggttcc tacagaaact attctaaccg cggaagaaag aaattgaaaa aaaaaattga 159600
caaaaacatc ataacataaa ggaccaccta cctgggacgc gcagttgggc ggcggactgg 159660
gacggcatgc tgcggcgatg ctgtcggtga tggtctcttc ctctctggtc ctgatcgtct 159720
tttttctagg cgcttccgag gaggcgaagc cggcgacgac gacgataaag aatacaaagc 159780
cgcagtgtcg tccagaggat tacgcgacca gattgcaaga tctccgcgtc acctttcatc 159840
gagtaaaacc tacgttggta ggtcacgtag gtacggttta ttgcgacggt ctttcttttc 159900
cgcgtgtcgg gtgacgtagt tttcctcttg tagcaacgtg aggacgacta ctccgtgtgg 159960
ctcgacggta cggtggtcaa aggctgttgg ggatgcagcg tcatggactg gttgttgagg 160020
cggtatctgg agatcgtgtt tcccgcaggc gaccacgtct atcccggact caagacggaa 160080
ttgcatagta tgcgctcgac gctagaatcc atctacaaag acatgcggca atgtgtaagt 160140
gtctctgtgg cggcgctgtc cgcacagagg taacaacgtg ttcatagcac gctgttttac 160200
ttttgtcggg ctcccagcct ctgttaggtt gcggagataa gtccgtgatt agtcggctgt 160260
ctcaggaggc ggaaaggaaa tcggataacg gcacgcggaa aggtctcagc gagttggaca 160320
cgttgtttag ccgtctcgaa gagtatctgc actcgagaaa gtagcgttgc gatttgcagt 160380
ccgctccggt gtcgttcacc cagttacttt aataaacgta ctgtttaacc acgttgcgtc 160440
gtgacgttgt ttgtgggtgt tgctaggcgg gctggaaaga tgatgtataa atagagtctg 160500
cgacggggtt cggcgctctg ccggctgcgg cggcactcgc tccacggcct ccgacgagcg 160560
ttgcgctcgc gctttgcgcc gccgcgtcat ggatctccct actaccgtcg tgcgaaaata 160620
ctggactttt gcgaatccta atcgcatcct gcatcaaagc gtcaatcaga ctttcgacgt 160680
gcgccagttc gtcttcgata ccgcgcgtct ggtcaactgc gtggacggcg atggcaaggt 160740
gctgcacctc aacaagggct ggctctgcgc taccattatg cagcacggcg aggcttcggc 160800
cggcgccaag acgcagcagg gcttcatgtc tattgacatt acgggcgacg gggagctgca 160860
ggagcacctc tttgtacgcg gcggtatcgt cttcaacaaa tccgtctcct cggtggtggg 160920
ctccagcgga cccaatgaga gcgcgctgct caccatgatt tccgagaacg gtaatttgca 160980
agtgacttac gtgcggcatt acctgaaaaa ccacggcgaa tcctccagcg gaggcggtgg 161040
ttgcggcgcc gcgtctaccg cttccgccgt ctgcgtgtcc tcgctgggtg gcagcggcgg 161100
gactcgcgac ggcccttctg cggaggaaca gcaacggcga aggcaggaac agcgtcacga 161160
agaacggcgc aaaaagtcgt cctcgtctgc cggtggtggt ggaggcggcg gcgctggtgg 161220
tggcggtggc ggcggcggga gcggcggtca gcactcctcg gactccgcca acggactgct 161280
gcgggatccc cggttgatga accggcagaa ggagcggcgg ccgcctccct cctccgagaa 161340
cgacggtgag tcccggccct cctcgcgtca cggtgctttc cgagtggact cgtgagcctc 161400
ccgtagcgca cgagcgagca ggcgagcggt gttggtgcgc tggtggttgt gtggatgata 161460
accatgtgct ttttcgtgcg ctatgtgtcg tcccgtctgt aggctctcct cccctccggg 161520
aggcgaagag acaaaagacc accgcacagc acgaaggcca tggcggcggc ggcaagaacg 161580
agacggagca gcagtccggt ggtgctggcg gtggtggtgg cggcggcagc ggccgcatgt 161640
cgctgccgct ggacacgtct gaagcggtgg cctttctcaa ttactcgtcc tcatcctccg 161700
cggtctcttc ttcctccaac aaccaccacc accatcatca ccaccataac gccgtgacgg 161760
acgtggccgc cggcaccgac ggtgcgttac ttctacccat tgagcgcgga gcggtggttt 161820
cgtcgccgtc gtcgacgtcg ccgtcgtcac ttctttcgct ccctcgaccc agcagcgccc 161880
acagcgcggg cgagacggtg caggagtccg aggcggcggc gacggcggcg gctgcggggt 161940
taatgatgat gaggaggatg aggagggctc cggctgaggc ggcggaggca ccaccgcagt 162000
cggaggagga gaatgattcc accactccag tctctaactg ccgtgttcct ccgaattcgc 162060
aggaatccgc ggcgcctcag cctcctcgca gtccgcgttt tgatgacatt atacagtcat 162120
tgaccaaaat gctcaatgat tgtaaggaga aaagattgtg cgatctcccc ctggtttcca 162180
gcagactctt gccagagacg tcgggcggga ctgtcgtcgt caaccacagc agcgtcgcga 162240
ggaccgccgc agctgtctcc gcagccggcg ttggcccccc agcagccgca tgtccgccac 162300
tcgtcaccac cggtgttgta ccctcaggtt ccgtcgccgg tgtcgcgccc gttgccgccg 162360
caatcgaaac accagctgct cctccccggc ccgtgtgtga aatcaagccc tacgtggtaa 162420
accccgttgt cgccaccgcc gcggctgcca gtaactcttc ctcgtcttct tcggctccac 162480
tgccgccgcc gccaccaccg tcgggcggac gtcggggtcg ggcccggaac aatactcgag 162540
gaggcggcgg tggtggcggt ggtagaaaca gccggcggca ggctgcatcg tcgtcgtcct 162600
cctcctctcg gagatcgcga cggagaaaca accgccacga ggacgaggag gacaacgacc 162660
ctctgctccg gttgtcgcaa gttgccggca acggccgccg gcgagggccc tcgttcctcg 162720
aggacggact cgaaattatc gatcccagcg aggaggctgc gatcgccgcc gcctcgatcg 162780
cggcgttttt cgacgattaa aaaaccgagc cgagaccgga aaaaatatga aacaggacgc 162840
gcttggacat ttgggtttcc accccttttg gtgtgtgtct atatatattg gtcactgatt 162900
ttttttacaa taaagagata gacatcacag ttcaccacct tgtctccccg gtgtgtctat 162960
tatcatcaat cacccacaga gtcgccagtc catggtctct cggtaatgcg tgtccagata 163020
cgcgttggcc agtataaaat ggtcgttgcc cacgaaggcg cgggtggtgt tgcgcggcga 163080
cgggtggcag gacttgagta ccaagtgccg ccgtcggtcg atcaggtact cgcaggtgtg 163140
cgcgtcggcg ccccacagca tgaacaccag atgctcccgg cgctctgaca gcctccggat 163200
cacatggtta ctcagcgtct gccagcctaa gtgacggtga gatccaggct gtccgtgcac 163260
cacggtgaac acggtgttga gcagcagcac gccgcgtcgc gcccaggcgt ccaggcaacc 163320
cgaggccgga cgctgaaacc cgtccaccgt acgcgccagt tcgcgaaaca cgttgttgag 163380
ggagggcggc ggcggtcggc ccgccagcgt gccgaaggcc aggccgctgg cgctgccgtc 163440
gcagtacggg tcctggccca cgatcaccac gcgcacctgc tcgggcggac acagatagct 163500
ccagcggtgt acgtgctcgg gtgccgggta caccatctcg agttgccgcg cgccctccac 163560
cgccgccacc gtgtcgcgca gcagcaccgt gtcgtggtcg ggcaagctga ggaagcggat 163620
ccagtcggcg ctcagacaaa acacgcgagc ctgctcgtcg ggggttaaca gagagccttt 163680
attatcagca atgttagcga gcatccactg cttgagggcc atagcgcgag tgagccggca 163740
ggttgacgcg cgtctgcttc agctcgggcg gcagtccggc gtagtattta tctaggtggc 163800
gtagtagcgg cgggtccagc tggtgacgca ggcagaattc cttcactgcg ttgtacaggc 163860
cgtaaaagag tgtgatgccc tcgggcgcgg cagcggtgct cacgggcaga cgcacggcgc 163920
ggttggtacg cgtggcttcg ttgcgtatgg ccaccaccac gttaaagaga gacggtggca 163980
ccagctcgaa gcctaacacg tgttccgtga agatgctgcg cccgtatgac agtcgcgtga 164040
ggtcgtagcc gcggcacagg tcgtccacgc acgtgtacac ggccggcgag ccatcgccgc 164100
actcgctgta gccgcgcatc accgtcatcc agcgcggcgc tgtgtccgag ctcaacagcg 164160
tcagcagggc ccgcaattga tccggattgt tgtacagcag ggccagagtg tccaggaaag 164220
catcgtccaa cagcacggag ttggcggcct ccggcgtaac gggacggtaa cgaataagtt 164280
gcgatagcgg gccatcgcgt ctggtaacat tcaccaacgg gcgcagccaa ctttcatact 164340
tgtcaccctg aaacacctca cccaacaggc atcgacgcgt tagttcgggg cactccgcgg 164400
ggactttctc ggcggcggta ggagcgacgc tgacggcgac tgaggaaaca atgggcagca 164460
gaaggcaaca ccacagcagt accaccggtc caggtgagaa agagaagccg caatccgggc 164520
ggcggcacat caagtctgcg gcacgatgag agtgtgacgg taaggagcca gttggcgccg 164580
aaagttggcg ctcaggtctt cgatccctaa aacgttatat attgcatcca gcaggtgagc 164640
caggctaaac ggattcacgt accaggtttg gttacccgcg acgatgacgg ccagaccgtg 164700
ggcgctacag ttggagaggt tcctgggtac gaaggtaact gagtcgatgt cgcgccacgg 164760
ggggaatgag acagacgact ggcgcacgct gtaatcacaa ctgtgattga cgtgtagcgt 164820
gtaatttcgg ttgcactcag cctcgaagta gagggggaac cacagttcgt cgtactcgtc 164880
gtcgtcctcc agttctggct cttcttcatc caccgcaatg tctacgctgc tctgagattc 164940
ctcttcgtac aggatgattg acaggttatg gctacacagg tcctgggcgg gaggacgcgt 165000
gggagcgcgg gtggtggtaa tgttttccag atcgtcaaaa gtcggagtgt agtctgacgc 165060
cgtgacgaca ccgtcgacgg agatggtaga agttgcggcc ggtgtcacgg tggtaagtat 165120
ggatacagaa ggggaggggg aagtagcgtt cgtaccgatg gttgtggtat tattattccc 165180
tgtgtttctt gttccagaaa ccgttgacgt tgagatggga atcgacgtgg tgctggacgt 165240
cagattgctg accgaggaaa ccgtggtggg agtggtgacg gtgttactcg tggttgaagt 165300
gacgttaggg gaggtagtag tggtaccggt ggtggcgacg gtagtgtttg tcgtggcggc 165360
ggcagcggtg gtactggtaa cggtggtcgc gttggtttcc accgcttcac acagtaagca 165420
aaagcacagg gccgggaaaa gcaaccagcc ccgccatcgc cgccgccgct tcatgaggtg 165480
ggcaggcgaa agctggtgaa ttcgttgtac agcggcaagt ggggcgccgc gatcgaaggg 165540
tacgtcaaca agctgacgtt gatattaaat acgtctggct gcttttctac gatggaagcg 165600
cacagggtta cggcgtcaaa caggtctttc ttggtggcgc ccgagaccca catctggtat 165660
acacccgtct cgtggtacga agtagagcgc ggcaccaccg gacggatgca gtccagaacg 165720
cggttgggat cctggtgaaa gaatttgaac gtggctacgg cctgtggcgt gtgcggcatc 165780
gtctgcgtga tgagctgctg gcccgctaac acggtgacgt tgtgcaactt gagcagggca 165840
ctcttgaggg cctggaaagc gttgccgcac gaggcgctga tctgcagctg cacggccgtg 165900
gagtcgtgca gccgcatgag acgtgatacc tcttcgaaga cgtacttgta tttgctggca 165960
aaaagtggcg cgtaccgaca gtcggccggc aaaatgtagg tggcgttacc gccgttggtg 166020
gccacggcgg gcgcagcggc cgcggaggcc ggcgtaaaca gcgtcagcgg ccggtggtgg 166080
ctggtaaggt cgatcatggg cggcgtggtg accgtggcgg tggcgggcat gacggggttt 166140
gcggcgacgg gcactccggc cacagcggcg gccgcggcgg ccacggcggc acttgccgag 166200
cccacacccg ccggcagtcc tccgccaccc atgacgccgc cgggcagagc gtcgcccaga 166260
cagacttccg cagtggcggg cgcgctctca gcggtcagta cggtttgccg atcgacctcg 166320
cgacgaaagc tggtgaggaa ctcactgtga tccatggccg cagggcccga gatcccggga 166380
ttctgcgggt gctgaccgag tgcggggcga gttatatgga agacgattag cttggagcgg 166440
agttttgcgt ccctagctga cctgcggatc agcgacgtgc catagggata gactgtgagc 166500
ggcggccgca acggcggggt cggccgccgc tcgtcgtcac ggggcggcgc gagggaggag 166560
gaggtggtgg gtacgatctt gacgtggttg acgtcctgcc cgtccggggg aatacgcaaa 166620
aaaccccgtc gcggcgctac cacgatggtg cgatgggtct ttctcttgtt ggccggggcc 166680
agggacttgc agatgcgtgt ggagccgtag acgatctgga cgtggtcctg ggagaacatg 166740
accatcgccg ccaacgctca gcggggggac gtgttgggaa cacagaggct gagggaaaac 166800
tccgtagaag tcagcgaaat aaagacaaca cagcagccac tcctctcgtc tcgggcccta 166860
ccactgcttg aagtagggca ccgggtgttt cttttcctca acgggctcct ccagtctctt 166920
ataggaccag tcccgccggc gcgccagcat gtaggtcacg tacaaaagaa taatcaccat 166980
gaacaccagg aaagccagca cgccgtaggc cagcagccgg tcctcgaaca gcgggtcgct 167040
cttgataaac acgtaggtgg tggtaaaact tcggcccgca atctgaacgt ggagacgcac 167100
gacagtatac gtgccgttga ggtagaagac aaactcgcgt aaccgttgtc cgttatacgt 167160
cacgttacta atattccacg gcggaatgag ctggttgccc tgatgcagat gcacggtgct 167220
gttggggtga tagaggctgc taccgttgag caagcagtgt tcgtgttcct gaagcagcac 167280
gcggacccgc atcgtggtgg cgttcaggcg agtcccgtac acggcgtaga tgggataggt 167340
gaaaaggtcc caagtggcgt tgtgatggcg gccccagctg aagaaagagc acgtgtactc 167400
agtggtctcc tgcggcctga gtcccgagat aagcagctct tgagcagtag cgttgtagga 167460
gagatgtagt tttcctgtgg ataaaattca taagttgttt attttgttgg caggttggcg 167520
ggggaggaaa aggggttgaa cagaaaggta ggtgctactt accttcatta tcggggggga 167580
aggcgctaag ataccccacc tgagtgaagg gacccttgca gtctgtccgt gcataacaag 167640
taactgataa aatgtctgga tttttggtgt tattcaacag gataactttg caggtggcgt 167700
ttagagacac ttggtcgtgg ctgtagctgg cttcgcaatt cacagtatac aggtgcccct 167760
ctttctgcgt cgtggctatc acggaagtgg aggcggacga ggtagaggtt tgtaccgtgg 167820
tggtgacagc agaagtgacg ttgttagagg tacttattga cgtagtagac gtgacggtgg 167880
tattactagg ggaagtgacg gcgcttgtgg tgctactttt cacccccggg tgcatgtcgc 167940
ccaagagcgc aactacgagc gcgatcgcca gtacggaaca catgttgccg tgtgacgaga 168000
cggcgtgtgg acgagctata tgtggcagga ggtcgcgtca cctcttgtga cgcctaaacg 168060
tccagctcca gataaaagag gcgttaataa tgaagaccac aaaaaccact tgcgtcagta 168120
tgacaatcat aaaggctcgg tgattgctac gcctaaagta cgcgggatta tccaccagtt 168180
catcctgctg aacaaagtgg atgattgacg tattggtgtt actatccgtg ttgttgacca 168240
tggatttgac taagaaagtc ttggcgccaa aagtcccgtt agagccccag caggtgacgc 168300
tgctattcac ataagttccc ggtgcccccg ctagcatgta tttcagttgg tgggtataat 168360
tttttctgtc gttatccatg tcattgctgt agttgacctt gctggtgaga aagcgtgttt 168420
tcaacggggc acttatcatc atccctgagg ccaaaaaggg cgaattgcaa gctgtagtgt 168480
tacaaaaaat agtcaagtta gtgtcattgt attgataaat gtaagccatg cttacttcag 168540
gctcatacca cccgattcca atcgcggccg ccatcgttac cacgtcccat cttcccagac 168600
ttaccaccgc caccactaac agcgtcaccc ccgcacggta catagttacc ctctcgacgt 168660
cgccggctgt caatgacgtg cctgcgtcag tggctatgat ttatagcttt tgggcccaac 168720
cgcaacggat ctgtcgtaat ctaccttcca cagggccgcc gcgacgatgc tgaacgacag 168780
gatcagacag acggcgtaca aaagtcctag gtcggcgtcg acgcggcagg tgcggatgtc 168840
tcgcagggtg ggtagatggg cgatgcacaa ctctttctcc ccccgcccgt acatcccatc 168900
ttgtatcagc agccgtagcg tggcattgat ggtcagcggg gtaaccaaag aaatcacata 168960
gggatgtgta caggaagtgc agtgacgggt atccgtgaga tgtaagtcac caccctcctc 169020
accgtcatca tgaaagacca ggactcgggt gagacgaccc gatgaatact ggatctccca 169080
ccacagtctt tggtccaaca ccgagagggc gcaagagatt ctaagtctcc ctgggttggg 169140
ggagcagatg taagtcccgt atgtgcctct cgccatcagg gccatacaca tgagggggag 169200
aaggacaatt atccgggacc acccgcaccc ccacatcacg agaccagaga cggagatgta 169260
taaaaaaagc tacttttatt aaacagcatt ctcaccacac gttaatactg tcacggggaa 169320
tcactatgta caagagtcca tgtctctctt tccagttttt cacttactga gacttgttcc 169380
tcaggtcctg gatggctgcc tcgatggcca ggctcagggt gtccaggtct tcgggagggg 169440
tctcggtggg ctgctcaaac tgccccacgg cgtaggcctt cgcggccgtc tcgtagatag 169500
gcagcatgaa cccaccctgg ttggtggaga agatgcgcac catgacctgt ttgggaaact 169560
tttgcatcag gggcaggcac aggttgagag cgcccaacag gtccacgggg gtggcagcgt 169620
ggatgatcat gttgcggtaa tcggaggaac gggggcataa ttggtgggtg tgcaattctt 169680
tgaggctcca cgcggccttg acgccttcgt tacaagcatc ggctgtgcgc tgcgccactt 169740
cgggtggatg tgtcacgggc atggtgtgct ccatgaggaa gggagtggag agggccaggt 169800
tgcacatggt gcccaggcga caccgcaccg catccacctc actcttcacc tcatgattgc 169860
gggtgtagat aatctggatg cccttgttgt tcacctgcat ggttttgcag gctttgatgg 169920
cctcatctaa cacctggtgc atactgggaa tcgtgaaggg caggttcttg tactcaagag 169980
agcgattggt gttgcggaac atgcggctca cctcgtcaat cttgacgcga ccccgccgag 170040
tctgcacgtt gggtgtgcag aagggggtgt tcttatcttt catgatattg cgcaccttct 170100
cgttgtccaa ctcggagatg cgtttgctct tcttcttgcg gggtccggtg ctcgccccgc 170160
cgctgctctg atggccgcag ctcagcagag aggaggaggc cgcgccacca aaaccgccgc 170220
gcccatggtg gctcgaggtc acggatgctc ctccgccact gctgcatttc atctcctcgg 170280
actcactctc cgagtccgaa gccgaactgc aggaggagga agacgaagag gaactatctt 170340
catcgggccg gcccaaggga tcgggaagag gagggtggtt catctgggag agcgggtgcg 170400
tgggagaggt cactcgcggc gtgccgctgc cggtggaagg ggaagacgcg gtagcaccgc 170460
gggtttcgac ttcttcaccc tgttcttcct cgctatcaga gatcacgata cagccggcgg 170520
tatcgataat cttgttgcgg tactggatgg taaagtcggg ctcgggcttg atgtcttcct 170580
gtttgatgag gggcagcatg ataggcgcgg gaggcacggg cggtttaata atcaccttga 170640
aaggacgcgt ggttttgcgc ggtttcttac gcgggctgag ctcgggagta gcggatgccc 170700
cggggagagg agtgttagta accgcgacgc tggtgggggt cggcttgtta agaggggcgc 170760
tgctaacgct gcaagagtgg gttgtcagcg tggggccggt gctactggaa tcgataccgg 170820
catgattgac agcctgggcg aggatgtcac ctgatggtga taagaagaca cgggagactt 170880
agtacggttt cacaggcgtg acacgtttat tgagtaggat tacagagtat aacatagagt 170940
ataatataga gtatacaata gtgacgtggg atccataaca gtaactgata tatatataca 171000
atagtttact ggtcagcctt gcttctagtc accatagggt gggtgctctt gcctccagag 171060
gcggtgggtt cctcagcacc atcctcctct tcctctgggg caacttcctc tatctcagac 171120
actggctcag acttgacaga cacagtgtcc tcccgctcct cctgagcacc ctcctcctct 171180
tcctcatcac tctgctcact ttcttcctga tcactgttct cagccacaat tactgaggac 171240
agagggatag tcgcgggtac aggggactct gggggtgaca ccagagaatc agaggagctg 171300
acaccagcgg tggccaaagt gtaggctaca atagcctctt cctcatctga ctcctcggcg 171360
atggcccgta ggtcatccac actaggagag cagactctca gaggatcggc ccccagaatg 171420
tactgggcaa agaccttcat gcagatctcc tcaatgcggc gcttcattac actgataacc 171480
tcaggcttgg ttatcagagg ccgcttggcc agcatcacac tagtctcctc taagacatag 171540
cagcacagca cccgacagaa ctcacttaag agagagatgc ccccgtacat ggtcatcata 171600
caagcgtcac tagtgacctt gtactcatta cacattgttt ccacacatgt agtgaggata 171660
tccataaata tgtgatcaat gtgcgtgagc accttgtctc tctcctcatc caaaatctta 171720
aatattttct gggcataagc cataatctca tcaggggagc actgaggcaa gttctgcagt 171780
gccgccatgg cctgactgca gccattggtg gtcttaggga aggctgagtt cttggtaaag 171840
aactctatat tcctgtagca catatacatc atctttctcc taagttcatc ctttttagca 171900
cgggccttag cctgcagtgc accccccaac ttgttagcgg cgcccttgct cacatcatgc 171960
agctccttaa tacaagccat ccacatctcc cgcttatcct caggtacaat gtagttctca 172020
tacatgctct gcatagttag cccaatacac ttcatctcct cgaaaggctc atgaacctta 172080
tctaagatat ctaaggcatt ctgcaaacat cctcccatca tattaaaggc gccagtgaat 172140
ttctcttccg tctgggtata ttttttcagc atgtgctcct tgattctatg ccgcaccatg 172200
tccactcgaa ccttaatctg tttgactgta gaggaggata acaacacata taagtatccg 172260
tcctcctgac tcatttatcg ctatctcgat gccccgctca catgcaagag ttaatcttta 172320
ctctatctga catacacaag taaatccacg tcccatgcag gttagtatac atcacataca 172380
tgtcaacaga cttaccgagt tctgccagga catctttctc ggggttctcg ttgcaatcct 172440
cggtcacttg ttcaaaagtt ttgagggatt cttcggccaa ctctggaaac agcgggtctc 172500
ccagactcag ctgactgtta acctccttcc tcaacatagt ctgcaggaac gtcgtggcct 172560
tggtcacggg tgtctcgggc ctaaacacat gagaaataga gtcataagca catgggtcac 172620
atacaggaga tatgtatata acattaatac aattttatta aaaaaaaagg gggggcacaa 172680
accccgacac gtaccgtggc accttggagg aagggccctc gtcaggatta tcagggtcca 172740
tctttctctt ggcagaggac tccatcgtgt caaggacggt gactgcagaa aagacccatg 172800
gaaaggaaca gtctgttagt ctgtcagcta ttatgtctgg tggcgcgcgc ggcagcaacg 172860
agtactgctc agactacact gccctccacc gttaacagca ccgcaacggg agttacctct 172920
gactcttatc agaacacaac aactcagctg cctgcatctt cttctgccgc tgccttaagt 172980
cttccaaatg cgtcagcggt gcaagcccgc tccccgagct cattttcaga cacataccct 173040
accgccacgg ccttgtgcgg cacactggtg gtggtgggca tcgtgctgtg cctaagtctg 173100
gcctccactg ttaggagcaa ggagctgccg agcgaccatg agtcgctgga ggcatgggag 173160
cagggctcgg atgtagaagc tccgccgcta ccggagaaga gcccatgtcc ggaacacgta 173220
cccgagattc gcgtggagat cccacgttat gtttaataaa aactgcgggc actggggacg 173280
gtggtgttgt atatgtgaat ttgtaaataa taaatgagac cccatcctgt aaaaatacag 173340
agtccgtgtc agtctctgaa ggacagtgta ttggcatata gccaataaag agagttgtgg 173400
caaagagcca tgttatggat tagtaatgga aagtatcgtc accaataggg gagtggtcaa 173460
taatggtcaa taacccacac ctataggcta agctatacca tcacctataa catgaggaag 173520
cgggggtgta tagaccccaa gccaaaaaca gtatagcatg cataagaagc caagggggtg 173580
ggcctataga ctctataggc ggtacttacg tcactcttgg cacggggaat ccgcgttcca 173640
atgcaccgtt cccggccgcg gaggctggat cggtcccggt gtcttctatg gaggtcaaaa 173700
cagcgtggat ggcgtctcca ggcgatctga cggttcacta aacgagctct gcttatatag 173760
acctcccacc gtacacgcct accgcccatt tgcgtcaatg gggcggagtt gttacgacat 173820
tttggaaagt cccgttgatt ttggtgccaa aacaaactcc cattgacgtc aatggggtgg 173880
agacttggaa atccccgtga gtcaaaccgc tatccacgcc cattgatgta ctgccaaaac 173940
cgcatcacca tggtaatagc gatgactaat acgtagatgt actgccaagt aggaaagtcc 174000
cataaggtca tgtactgggc ataatgccag gcgggccatt taccgtcatt gacgtcaata 174060
gggggcgtac ttggcatatg atacacttga tgtactgcca agtgggcagt ttaccgtaaa 174120
tactccaccc attgacgtca atggaaagtc cctattggcg ttactatggg aacatacgtc 174180
attattgacg tcaatgggcg ggggtcgttg ggcggtcagc caggcgggcc atttaccgta 174240
agttatgtaa cgcggaactc catatatggg ctatgaacta atgaccccgt aattgattac 174300
tattaataac tagtcaataa tcaatgtcaa catggcggta atgttggaca tgagccaata 174360
taaatgtaca tattatgata tggatacaac gtatgcaatg gccaatagcc aatattgatt 174420
tatgctatat aaccaatgaa taatatggct aatggccaat attgattcaa tgtatagatc 174480
gatatgcatt ggccatgtgc cagcttgatg tcgcctctat cggcgatata gcctcatatc 174540
gtctgtcacc tatatcgaaa ctgcgatatt tgcgacacac agaatcgccc aagtcaccaa 174600
agtcgtctat cgccatcccc cgtaaacgat ataagcgcta tcgccagata tcgcgtatgc 174660
ccaaaaatca cttttggaaa aatggcgata tcagttacac agaaactcac atcggcgaca 174720
ttttcaatat gccatatttt caaatatcga tttttccaat atcgccatct ctatcggcga 174780
taaacaccac tatcgcgcga catgaattta gtcggcgaca gaaatctcaa aacgcgtatt 174840
tcggacaaac acacatttta ttattcactg cagcatatag cccattttag cgcggcacac 174900
atccagccgt ttgtgttttt taacgctctc caggtactga tccaggccca cgatccgggt 174960
tatcttgtcg tattccaggt tgatccatcg atagggaacg ctgccagcgg cgcccagcag 175020
gtactgcgcc ttgtcgttca ctttgccgca gcgtattcgc ccgtcagctt cgaggtataa 175080
cctacaacac ggaggggaag ggggggtaca aaacgtgaaa ttagactttt tttttaatga 175140
tgttttgtcc ctctgtctta ctttcccata ggctgtaagg ccctcgagga agagacttac 175200
ggattgtagt tgcagctcgt cagtttgttg tgtacgacct ggcgtgtcaa tgaatgggtc 175260
atggtggtga cgatcccgcg aatctcagcc gttttctcgg gactgtagca gacttcgccg 175320
tccggacacc gcagcctgtg gattcatgaa aatctactct ggcattcccg aggatcgtcg 175380
atggaacatg gctatcagaa acgtcgagag acaaatccag acgcaccaca gaacgcagac 175440
aatcataaaa atacgtacgc gacggtgaag cgattgcaca ttttgaaatc gtaacagcgt 175500
tccggcgggt ggttgacgtt tatgaattcg caacattctt ctgcgcgcac ccgcggcacg 175560
cggctgtgac ccaatagcag ccacaacgtc gtcaagaacg gcgtcaggtc tttgggactc 175620
atgacgcgcg gttttcaaaa ttccctgcgc gcgcgacggg ctcaaacgat gagattggga 175680
tgggtacaga aggtgtaagt ctggttattg gcctcggtga acgtcaatcg cacctgaaaa 175740
gacacgctgt agtcccggaa gacgtgggcc cagctctcca gcttcatcac acacatctga 175800
taacgcgtgc catcgttgac gacgaagcgt agcagcttgg tctgcttggg caccatgtgc 175860
gctccaaaaa tcttggcgtc ttccacgctg atctgcacgt ttccgtcgct cggtttcgaa 175920
gccgtttggg gcatccgttg gaggatggtc tggttgcgac cgctcagata ccagatcacc 175980
tttttcaccc aggtggagct tctctccacc aaggtctggc cttcccggtt gtacagcaga 176040
tacagggtct cgttgcgaca ctcgggaccc gttgatacct gctggaaccc cgagaattgc 176100
aagggggacc gtgggggcga gggatagaga aaaggacagt aaaacgtcgc cgcgtcatgc 176160
ggtttggaat acgtcagttt agaccatggc ggggacggat tctggtttgc cgttagcgtc 176220
gaccacggag acgccagaca gggcgttgcc caaaccgcgc acagaagcag gcagtgaaag 176280
tggtgacgaa gcagaagccg cagcatatta tttcccgtga cgcaggctag ttggcaaaga 176340
gccgcacgct gaactcgagg ctccgggcgt gtggcgccag cgaaccggcg gcgttgaacg 176400
tggtcctttt gttggtgccg ccgcgacggt tctgacgtct aaagtcgctg atgagcaacg 176460
acacctcggt cacgttgatt ctgcaagcac aggttccaaa cgtcatttca taccccatgc 176520
ggttacttag ccgttacccg ttcgccctta ccttcccgtt gtcatgcacc tttagcgcgt 176580
accctcacct cttgagcacg tcaaagttgt ccaagccgtg gctcgcatcg tagtggtagt 176640
tcaacgtgag gtccacgagc tgttccacat acttgtaacg ggtttggtcg ggcagcgcgc 176700
gagagcacgc gtcccagtaa tgcggtactc ggtaataatc gttttttttc cgcggtttcc 176760
cgctggcact gacccagcac cacggcgcac agacaaacag acagccacac ccgacacagc 176820
cgcatgttgc agactgagaa agaaagcttt attatgagac atcatacaca tagtataggc 176880
gaggtgatgg ggcggggaaa gagttggaac cgaaagacaa aaaaaaaagc ctagtcgtac 176940
tcgggatctc tgagcgagac gggttgcatg gcaactttca ttagtttggg aatctgccag 177000
ctggtgctgt tcgaaggttc ttccatttcc gaggcggtca gttcatcgta caccgaaacg 177060
tagtacctga tggggtcctc ctcattgtcc gagaggtgag attcgatggt caaaggcgag 177120
cctctcccat aattgggatt cacgaacgac gtgtccaagt tgccatcctt tctgaaatag 177180
atgacgttct caggatcatg tttcatgcgc tcgcgggccg cggacgcctc ctcctcctcg 177240
tcccagtccc gagtttccaa ccgctgataa gggctcgagg aacaaaatcc ggcggggatc 177300
tgagaacctc gtcgggaacc gctgccaaac gggctgctgc cgccactgtc gtccgtgtcg 177360
tccaacaggt tgacggcctc ttcgtcggcg aaacgaaagc ggcccgggtg cttgcaacac 177420
gaggagtaaa ctaccgcgat cagtaccgct atgaagctga aaatggaggt gcctgtcacg 177480
atgtagaaga ggatagccag cactttcatg atttcgtcat tgcgcgcgtc gtgaacggaa 177540
gattcgcggg cagtggtcat gttggtttcg gttgtaggtt cgctactcgt ggtgctctcg 177600
acggtatttc tgctgctggt gctagtaggg acgtttgtgc tgctggtcat atttgtagcg 177660
tcgctgaagt cgatgtgaag cagcaacccg aacgcgacca ggaccaggaa tgttgcgcga 177720
aggagacccc gcggggccgg cattcttgag acgtggcgac gtggatttct tgttatgtcc 177780
gcgaacgacg tgtaacgagg acgtggtttc cgcaagcctc taccgacgcc gcgacaccag 177840
gtaggttatc aaaacgcgag cccatatcgc cgccatcatt gtaatcagca atgtgttgag 177900
gtactgcacg atgaatctgt ctagtgacac cagccaaccc tctgcttttg cgggcaagcg 177960
cgctttcggt gacagggtgt atcgtacgta gccgcgggtc aggcgcgcgt tgtagcggta 178020
cacgcagaaa tctatccaca ggccaacgcc cggctgtagc ttcggatggt ggataatagc 178080
gcggtgacgt acgccgcgtg gctttagaat ctccacctgt aaggccatct cctccaggta 178140
gtgggtctga ctgcgacgca gcgtccagtt catgtaaaag tcggtctcgc cgtgtccggc 178200
cacgaagagg ctgcttacta atccagtcta cattgtgcca tttctcagtc tgattgcatt 178260
ttttagagtt atgttgccac caacgtatcc tgttacgttg attacctcgt aactgcggtc 178320
gcatctttta tggactgtat aattgaaacc atcacaagta acggtcgtgg tggtgttggt 178380
acatgtggta gtctcaacgt ttgtatttgt cgttgtggat atctgtgtgg ttgttttcga 178440
cggttttgta gaaacggtgg ttgctggtgc agttgcagta gagcaattta tagattctga 178500
agtgctttta ttgctgataa ctgttgtact gtatgttgat gtggctgtct cagtactagt 178560
ggaatagtta acggtagtac tacagggaca ttgacaggaa caggtttgat tgcagctttc 178620
tgataacgcg gatattagta tcgtccacat aaccgtaaat cgccagtcca ttgcaatatt 178680
agttctcgct caatgggcat taatattcct ttgaacgctg agccttacag aatgttttag 178740
tttattgttc agcttcataa gatgtctgcc cggaaacgta gctcaatctt catgttctgt 178800
gtgatatcga acaatgaatt ctgattcact gacggtgtct tgcaacatat ggtacttttt 178860
gttaaaggct cgtcgtgcaa aaaacagaac tatgcaggcc atacaaacca acacgatggt 178920
ccatacggtg cggcttcttt gcgagctatg atagagatta cgtttgtggt gatgtgtatt 178980
gttagtatgt tgacttcctt tctctctatc ttcattttcg atatcggtgt tgtatctagg 179040
gcaaacgaaa gtagcattaa tagcttcagt atgatttttt ggtgttacta ataggtagaa 179100
attttcatct tcgtgatgtc ctgtgaagta attttcttta aaacaacgtc tgctgtacct 179160
gccggaattg gtgatattta gatcgtacag atgtagttct gtgttgttgc acgaacgaca 179220
taagtcatgg tacagtgaag gtctttcatg ttgagaatga catacagtat gagaggtaag 179280
gatgcgtaac caataccaag attgggtatg tgcgttctta cgatgaccta gatgatgtcc 179340
gtgtgtggat cgattgtaat gtcgtatcca ggcgactgaa agacaatccc acgtagaatt 179400
accttttatg gtgacattac tcccttctat tcctgttgta ttagtttctt tgaaacgtat 179460
gattgttgtc tctgtgtgac aagcgttgga agagttagta cggttgtacg tggtgtacgt 179520
tgtggcgctg caatttgtaa gccatggcgt gcttataagt gcagtattag tggatacgtt 179580
gtgcgaagtt tcatctgacg tgatagttac ggtgattgtt gtgttataag atgatgtagc 179640
gtttgctgtt acgttggtaa aagataatat agtgttggta tttgttgaaa tcaattctgt 179700
agtggcagcc gtattggata tattagcata tgatgtattg aatgtagaat atacggttgt 179760
gaaagtactc aagtcggagg taacgttggt gatgttgcca atggttgacg cttgtgaggt 179820
gacagatgtg tgtggcgtcg ttgatgtgtt gttattcgga gtagaaaata cgctggtcac 179880
aaaggtggta gaagcagtgt tgggtgatgt gatggatgca gtattggtag tagtactgtt 179940
gcatgtaact ctatgcagaa tatagaatat tatgattgta tacgccgtat gcctgtacgt 180000
gagatggtga ggtcttcggc aggcgacacg catcttttac tgtaaatccc cgtccaccgt 180060
caacaacaaa ggttccgtat ctaggtccgt ccgcagatgt tcagcgtcct gttccccgat 180120
tcgttgcgat cgcaggaagc agatgaccag cgcgccaaca aagatcatca ttcccgaaac 180180
ccaggcgcaa tggagtgaga ggccggacca ctggcgtttt aaatccgaga taattgcccg 180240
gtctgcctct tgggaatccg taaccacaac tctccctggt cccggataaa agcatcgacg 180300
cgtttccaag gctcggcaga agctacgtgg gtggatgatg aggtagaaag cctcgacatc 180360
gccggtatac tgatcctgca ggaggtagac tcccgtatct ttaaccgtga gattgtacag 180420
cgtcagattt tggcgcgtgc acgcgaacgc cgcaccgccc tgacgcgtgg tttctttata 180480
ggcgtctgta atgatacaaa gtggcggcat acgacgcatg tatctgctgt agatatcata 180540
acgctgccag actacgctgt gatggctagt gttaagcctg gtaaccagcg tgcgtgtacg 180600
gtcctcgcag gtggcacggt agttggcgag ctttaggggt tttttggttg gttcgacggc 180660
gttcgatgaa cttccctgag ttgtgaacaa aaacagcgac gtgactatga caagcgtgag 180720
gggggtgctg taggtctgca tggtgcaaaa cacgttctcg ccttccttat cagacgttgt 180780
cgtcctcgtc ctcttcgtcg tctgtgcccg tcggttcgat caacggggag ttatctttct 180840
gtctggaggg tcggtatgga atccgttcgt agatgttctg ctttttagcc gcgtgttgtt 180900
ccagcttttt gcgtgtcagg ctccgatagg ccagacattg atctacctcg gtgcccgtgt 180960
tgtttttctc ctcctcgcgc gcgtaaatta caaagaagac caccagcagg actatcagcg 181020
tagccacgaa cgagcccgcg ccccaggccg agtatgcgcc tagcatggta atgggttctg 181080
tgatccggca tttgcacatc gcgtggcact tgctgccatt gccggtatta gatgatgtgt 181140
tattcggact gcacttgcac gtcaaatggg tattttctga tttcacgaga cagttggtgg 181200
cgactttggt ttcggcgcag acggccacat agcttaccaa gctgagtgcc agaaagcaca 181260
ccgcgtgcat tacacgcgga tacatattaa aacaccgtgt tccacaagca ccgcacacgt 181320
caatcctccc cgcacggtct tcagcccgcc catgacatga tctccctcac gttacccttc 181380
aacaccctgt agtactctgt ctcggcttcc ggtccccatg tcctaattat aacaaaacac 181440
cgtgacactg tccatctccc tgtctttttg cgccgccggt cccccccaaa tcatgtctct 181500
agatgccgcc ggccaccaac cggaggcacg gcggctattg gattcggcat tggtgcgccg 181560
cgtcttggcc tgcatgatca tcgtcatcat gattgccatt agcatctgga tcctgaccta 181620
cgtgctgttt ctctaataag aaccccggcc cctgacggta attttccttt cttctccgtt 181680
tctcctcagc tgccgtacgt gatgcctcac ggccatctcc gacaggccct ctccccgacc 181740
tcctggacat gtgagggctt gttgctcctc ctgggattgc tggtgctctt ctttcaccac 181800
cacaaccagt cggccgtgga gaggcgtcgc cgcgtctcgt tcgtcgaggc cgatcgactg 181860
ccgcatgaga gcgggtggta ttcttccgat gacgacggag accgggacgg tgatgaggaa 181920
actggagaga gccacaacag aaacagcgtg ggactgtccg ctgtttttag ctgactggcg 181980
tgcgacctgt aaaccgttac tcgggtctca agatggtttg gaagttgtga ctcatcttcc 182040
tgtgggtgat acccaaccgg acgcgagtgt tccataaaag ccgggcgctc cggcgagacc 182100
atgccatcct cgccttcgga cgccccgctc ctcttctctc tcctctcctc cccgctgccg 182160
cggccattgc cgccgccgcc cataccatcg gcatgtcggc cgacaaatcg cagctgtctt 182220
cgccgccgca gctgtagcag ttaacgtcgc cggcctccag gaggagatgg cgctgtgcgt 182280
cgtctcttcg tcccgtctcc ctctgtggtc gtgggtggtg cgagagtaca cgatgggtgg 182340
ctctcgtctc gggggaccac agggggaggg gggtaattta ttattcgtat tactgtaatt 182400
ttgtatcgct taatttgttt agagccgcac gcttgacaac gccttgtata gccttattta 182460
tcccgatgac ttttttctcc gtacaagaaa tggacgtcac ttgagcagac acagtttcat 182520
cgaccacgac agtctcatga tctgactacc tctgacccgc caacgagaaa accgaaaagt 182580
aaaagatgac cgcgccctcg gagtcctttt ttccttttca atcatgaaag caagaggcag 182640
ccgagagaat gccagtaaga gacgaccatc gcagacacag tacgatactc atcttagaac 182700
gaaccagcga ataaccatca cacgtacagc agaatctcat gaactagtca accaacgtca 182760
taaaatcttc acacaatcgt ttttgcgaac ttttaggaac cagcaagtca acaaaagact 182820
aacaaagaaa aaccatcttg gaattaaaaa aagtagcatc gttaccttat gaaccagcag 182880
cattcagtat atacaccaga tataatatat ttattaatgt atcctctctt tctcctgatg 182940
taattttgtt tttgtaaatt caattgttga aagtctctcc ctgggggaat tgcatatctt 183000
attgatgaag aagaaatccc tgccatatgt gttgtcaaac tatcattatt tctctatatg 183060
ggtatttttt ttctaagaag caaaagacta gcagcagcca aaataaacct gatgaaatct 183120
ttaactgaac tcccagtggt ctgtgtgtat atttctgttg gtggtcggtt gtctgaaccc 183180
gggtgggttg ttcggaaacg gcgggacggg gaaacggatg gaaacagcgt cgctatatac 183240
gtgacttttg atctaaacgg acgtcgctag gctgacagtt tacgaattgc taaacaagat 183300
aggaacaaaa caagcggggc tttgcctggt aggatttcct gtggaaacaa taaccggatg 183360
tgattgtggc tggtacataa gctggttctg gctgcaagcg cttttcactg cattaggttt 183420
ggcgtttgct tttgcctggg aacgctatgg ctataacggg aaagaaccgg tttggcaaca 183480
ttccattgtg gggggggggt acttatagcg tgcctagcta tgacgttgat atatgtggat 183540
gcggataata ctcgtaatga gctaaaagcg acgactggta gtaattttac cattacgcat 183600
aggaaagatc cgttgacaac taagtggaaa accgtttttg gtaacaatgg tgatcagtgg 183660
ttgtgcaacg ttacgggtat aggtaatgct actgtgaata gtaacgcaac tatttgtgtg 183720
tcgagctgtg gtcataatac gttggattta tgtaatttaa agtcgggaga ttctggcttc 183780
ttcgatctgt ctcgttggtt cggtgaaaac atggatgaat acagtggtga tgtgtggcac 183840
ttggaagtca gctaaatgtt gtatcgctta gtgaattggt gttcttacag ttttcatgta 183900
ataaactacg tgtaattcgt taaatttgtg tgtttttttg ttagtattct gcgtaacggt 183960
ggaataaaat tgcgttgacc tagttagatt tcctgtgtag aacaatgacc ggacgtgctt 184020
ggactggtac atacgcaggg gctggacgtg gttaccggtc actggactcg gtttcgctgt 184080
agctgtggtt caacctgaac atggctccca gagctgctag gaaccggtcc agtcacattt 184140
tttggtgggt ggggggtact aaaaaagtgt ttaatatttg ggtttaatga taaaatccag 184200
gttatggata tgaggaaact gaatacctcg cagggtcgaa atcttaccac agttgatgat 184260
agaagacggt tttccatcgg gtgggaaaca tgggataacg gtggtgacta ataatggtac 184320
aacggtcgtc aatacaacag cctgtgtttc aagttgttcg catacgtcgc ttgtgctttg 184380
caatatgacg cagcagactg attcgttgta cggagtgggt catcggttga atgacgaaga 184440
agatggtgaa ctgtggagag tttcggtttc ttaataatcc catacgacat gtgttcattt 184500
atatctgaat tttaggatga tgactatagt ataactctgg ggaacaaata tcatacgtta 184560
atcactttaa gttacgccgt taggaaaaga aaatcagtcc gaatgaagca tagtcagccg 184620
aatgatacag caatagcttg tttacaacgt gttctttttt acattatgaa cgtgccttgc 184680
tttttataca cacatggaga cagaggtccc tcagcccttg tcacgacaac tccctttttc 184740
taaaccgtat gtgctccaaa ccgtatctcc tcatcgtcac gtgaaatacc atgggacccc 184800
ttttcgtcac acacgtcttt ccgcttaccc aacgcgtcag cccgcgctcg gcagagctac 184860
catataaaaa cgcaggggtt tagcagcttc cccagatcgc tgctgccccg gcgttctcca 184920
gaagccccgg cgggcgaatc ggccggctgg tcggtcggcg ctcggacgga tggggagaac 184980
ggcggtgact tagccgcccg tggccgggag aagacggagg agccgagatg acaacagcag 185040
tcgtggaagg gtcgccaagc cccggtcctt ctcttctgtc tggtcgaatc ttgttttctt 185100
ttttcaaccg ctctttttgt caccttttta tgtgagtttc tcttccgcgt ctcccggccg 185160
taccatccac ccatgcagca tgcacgcgtg tatgtatgca tcgcctctcc tccgtcccga 185220
ctaccatcag cagtaccact gccgccaccc ccagcgccac caccgctgcc gtcgccaccg 185280
cgttatccgt tcctcgtagg ctggtcctgg ggaacgggtc ggcggccggt cggcttctgt 185340
tttattattt ttttttattt tttatcttct cctttcctta atctcggatt atcatttccc 185400
tctcctacct accacgaatc gcagatgata aacaagaggg taaaaagaaa aaagctacag 185460
acatttgggt acctcagctt tccgataact cgaagaattc aaagtcgacg attcccaaca 185520
agagaaaaca gaacaaaaac aaggtcattt ttatttatcc tcatcgtcaa caacaactac 185580
cgacaacaac gaaacaccac caagaatgtc aatccgcaag ggtgttcctg ccccctcgac 185640
gcgcctgtcg cgatcctcat ggcgaggacc gcgatctccg tataggtaga tgaaattatc 185700
ccgtgtccgg tcctgattcc ccgcatgccc tgcacatcct gacgcgtcgg tcagcagcca 185760
aacaatcata ggaaatgaac cagaagaaca aaaagatcat ctctctcggt gtatagcaac 185820
accaacaaca accgcatcgc aacatcttca tccgcaagac ggaaagaaaa caacaataat 185880
gagaatgaaa tcaccacaac caagccagat ttcacgtcca tgagttttta ttatattatt 185940
atcaaaacga aaaacagaaa aactgtcata gataaatata aaaaaaaata gaaaccacaa 186000
acgactacta gtactccaat cttagatgta tatgctccta gataagattt agtattacca 186060
taatcatcga agaatgaaag acgacgatga ttccttaccg ctcctgccac ccggtctgta 186120
tgtagagaga gaagagagaa aacggtgaat ccaagatccc cgggtcggcg tcggcatgcc 186180
gctgatcgca gtggccccac ctcggcatgc cggcgccggg cgaggaattg ctcatgaaaa 186240
aaagtatctt tctgtaaaaa aagaaaacaa tacatgatta accgaaaaga aaccaacaaa 186300
aagaacccga gatcagtcga tttcgatcac tacgataaac acatggaaga tttcttgaaa 186360
aaagaaaaga gaaagagacc accttcccgg cggcggacac gctcctctcc gtcgccgttc 186420
tgcaccatga ttcgatcaat aacaacatca tcatcggaga ccatctttta atcaatcagc 186480
gttgcagtag tcgactccct ggacacgaag gagtcatcca tttttatcct cgcacttctt 186540
cgctctcaaa gccgccttta aagttgaaat gaaaggatgg aaacatggaa tacagtttta 186600
attgcacgta tcaccatttt actacaaaaa gaaaaaaaaa caacttacac atagtattac 186660
cttaggttta cggataagta gagtgtaggc gtttttgaaa cagttcagcc aatgcaatct 186720
tgtctcggca taatcactct ttctgcatat aatagtagta gtagatttat tcacatcaac 186780
acagcgaaaa actccagcat caaagtacac ctagagacag cccttaaaat atagtttgca 186840
gcttttagat gtacttacac caaagaagat taccgtcctt acgagaaaac agatactcgg 186900
atataggaat caagacagct ctgcactgaa aacacactct cctgtcacga caccgcgcca 186960
caccagaggc gtacgcgtga cttcatcgca acgatccatc gtgatgtccc tcgcagaacc 187020
taaaaagacc aaaaaaaaat cttggaccac agttgtcgat acttgaagac aatattctcg 187080
tgagaacttt gagattcgca cttgaaacct cttaggatcc acaaaaacaa caacctctgt 187140
atggaaaatg cgctatttta tctcagcttt tctcccaaac ctcggtttct tcctattctt 187200
atgttttccc tagtatattt gcctccttat aagaaaagaa gcacaagctc ggtcgcacgg 187260
attattcctt ctgctaatct attattttgt tccttttttt tttctttgcc ttcaccctct 187320
tcactccctg tagcaacaca gagtagtaga cacaataaat gagaagtttg catgcatttg 187380
tcgtgtccgt ggtttgttat ggcgtgtgga gtgctcggga tgggtggacg tggggacgga 187440
ttcttgaggc tacaaagata cgcggagacg tcgtggcgag gggatgggtt tattggatat 187500
cggtgaagca gcgtggcggc gaaagacgcg atccctgggc tggtagatcc ccctaccccg 187560
tctaccaggg acgtttatcc tttggacacg taaatgtctc ggccggcatc cacgcgccac 187620
gttcaccgcg ttgtgcccag cgccatgtgc gggtcgtttc ggcgtgaagt tggacggcgt 187680
agtttcgggg attgtgaacc gtggctgagg gtgtagatgg gacaggaaaa agcgtgtgat 187740
ctgaccgagg cgaagcatgt gggtggtgcg atgcggtgga tgtggcgggg tgcggcggtt 187800
tccgacgtgg agatgtggag atgggggtga tccggatgcg tggcaagagg cctcgagctt 187860
gggcttctcc cgcggatgga cgttctaact gtacacggcg gccgtggcct ccgagtaaaa 187920
aaaccaggtg ctgacgccag acagagacgc cgtcctcgga atcgtgtgcg cgaaagcctg 187980
tgccgcggca gcgtacgacg ttccagtcag cgaggccgtc gcgttggcgc gccaacagta 188040
aggtgacgac aggttggcgg cccatggttc cgaagcgtcc ccacatgcac cagcagtcgg 188100
cgtcaaagtc gcttgcgctg tcggcccagt cgccaccgcc gcggcggatt tccgcgcggg 188160
ggacggggta gccgagtgct gcgccctcgc caatgttgtg aagtggatgc gtgagttgat 188220
gttgattctc tgtgggaaaa tgagcgctgt cctgtgggtt ggtgttgggg tatgcgagta 188280
gtaggggttg tgtttgatcg tagaggtgtt ggcgggcctg tgcgcaagca gcgtagtctg 188340
cggcgtcgag ctccatctgt gtgcggtgtt cttcgtcggc gtgtttgtcc gaggtttgga 188400
catgcggttg tgtgttgctg tggtgtaagg gtaacgtgtg ttgggcgtct gggtgaagcg 188460
gcgtggtgtg ggtgctgttt gtgtctgtgg ctggcatgat tgtgcggcat gtgtgtgttg 188520
tagtgggtgg aggttaaata ggtgaggtgg gttccctggt ccgcgccgca aactgtcccc 188580
gtccccaacg taacctcccc tacgcggcgc gaacagcccc ggccccagcg caacccccgt 188640
ccccggcccc aacaccgtcc cgcacacccc ccgtctccgc aacaccccgg catcgccggc 188700
ggccagaacg ctcgaaaacc cccgacaagc gcagcgccga aacgacacag gcaaggaccg 188760
tggaacgcac cggcagcgcg ccgaaacacc gtcccgaagc ccggtgccga caacaaatac 188820
cgtgggacga cacgcaccgg cagtgcgcag gcagcgtcgg acacaacacg cttacggccc 188880
tcaacactcc ctcgaggacc caccacgcgg ccccgcaccg gcggtgtttt gggtgtgtcg 188940
gggcgcggcc gggtgggtgt gtgccgggtg tgtcgcgggc gtgtgttggg tgtgtcgggg 189000
gtgtgttggc agggtgtgtc agggtgtgtc gcgggcgtgt gccgggtgtg tcgtgccggg 189060
tgtgtcgcgg gcgtgtggcg ggtgtgccgg cggggtgtgg tggcggggtg tgtcggcggt 189120
gtgcgcggcc tcggggtgtg cggcttcgca ggaacgagtg tgtggcctcg cggccgttat 189180
ttcccccgcg gtccccaggg ccgtcgtccc tcgcccccgg gcgttgcttt tcgtgtgtcc 189240
ccagggaccc atgctgccgt cccccgggaa cttcctcttt tccccgggga atcacacaga 189300
cacagacacg cgtcttcttt tcgccgtgcg cgccgcacgt cgcttttatt cgccgtcgcc 189360
gtcctccgca ccacacgcaa ctagtcgccg tccacacacg caactccaag tttcaccccc 189420
ccgctaaaaa cacccccccg cccctcgagg acccaccacg cggcccggaa tggatgtcgg 189480
gcgtccacct agatgggtgc gcgcccggga ggcggctgtg cgctccagtg gtacgcgcct 189540
gccgcgcgtc ttccttcggg tagctgcctt tcccagtcca cggccttcca gactgcgtgg 189600
cgccaaggcg gcgccagcac gcgccgtgca cgtcgctgcc tataaaagcc agctgcgtgt 189660
cgcccgcggc acacgggcga cgaaggcgtc cgcgtgtcta aaccgcgtgc tcgctgacgc 189720
gggtttgctt cctatatagt ggacgtcgga ggtgtccggc gcccatggcc cagcgcaacg 189780
gcatgtcgcc gcgccccccg ccccttggtc gcggccgcgg ggccggaggg ccttcggggg 189840
ttggttcctc tcctccttct tcttgtgtgc cgatgggagc gccgtcaaca gcgggcactg 189900
gtgcgagtgc tgcggctacg acgacgccgg gccacggcgt ccaccgggta gaaccccgcg 189960
ggccgccggg cgcccctccg agtagcggca acaatagcaa cttttggcac ggcccggagc 190020
gcctgttgct gtctcagatt ccggtggagc gccaggcgct gacggagctg gaataccagg 190080
ccatgggcgc cgtgtggcgc gcggcgtttt tggccaacag cacgggccgc gccatgcgca 190140
agtggtcgca gcgcgacgcg ggcacgctgc tgccgctcgg acggccgtac ggattctacg 190200
cgcgggtgac gccgcgcagc cagatgaacg gcgtgggcgc gacggacctg cgtcaactgt 190260
cgccgcggga cgcgtggatc gtactggtgg ctaccgtggt gcacgaggtg gaccccgcag 190320
ccgacccgac ggtgggcgac aaggccggcc atcccgaggg tctgtgcgcg caggacggac 190380
tgtacctggc gctgggcgcc gggttccgcg tgttcgtgta cgacctggca aacaacacgc 190440
tgatcctagc ggcgcgcgac gcggacgagt ggtttcggca cggcgcgggc gaggtggtgc 190500
ggctgtaccg ctgcaaccgg ctgggcgtgg gcaccccgcg cgcgacgctg ctgcctcagc 190560
cggcgctccg acagacgttg ctgcgcgccg aggaggcgac ggcgctcgga cgggagctgc 190620
gccggcggtg ggccggcacg acggtggcgc tgcagacgcc gggcaggcga ctgcagccga 190680
tggtactgct gggcgcgtgg caggagctgg cgcagtacga gccgttcgcg tcggcgccgc 190740
accccgcgtc gctgctgacg gccgtgcgtc ggcacctgaa ccagcgtctg tgctgcggct 190800
ggctggcgct gggcgcggtg ctgcccgcgc ggtggctggg ctgcgcggcg gggccggcga 190860
cggggacggc ggcggggacg acgtcgccgc cagcggcgag cggcacggag acggaggccg 190920
ccggcgggga cgcgccgtgc gcgatagcgg gagccgtggg gtccgctgta cctgtgcctc 190980
cgcagccgta cggcgccgcc ggcgggggcg cgatttgcgt gcctaacgcg gacgcgcacg 191040
cggtggtcgg ggcggacgcg gcagcagcag cggcgccgac ggtgatggtg ggttcgacag 191100
cgatggcggg tccggcggcg tcggggaccg tgccgcgcgc catgctggtg gtgctgctgg 191160
acgagctggg cgccgtgttc gggtactgcc cgctggacgg gcacgtgtac ccgctggcgg 191220
cggagctgtc gcactttctg cgcgcgggcg tgctgggcgc gctggcgctg ggacgcgagt 191280
cggcgcccgc cgccgaggcc gcgcggcggc tgctgcccga gctggaccgc gagcagtggg 191340
agcggccgcg ctgggacgcg ctgcacctgc acccgcgcgc cgcgctgtgg gcgcgcgagc 191400
cgcacgggca gtgggagttc atgtttcgcg aacaacgcgg tgaccccata aatgatcccc 191460
tcgcatttcg tctttcggac gctcgaactc tcggtctcga cctcaccacc gtcatgacag 191520
agcgtcaaag tcaattgccc gaaaagtata tcggtttcta tcagattagg aaacctcctt 191580
ggctcatgga acaacctcca cccccatctc gccaaaccaa accggacgct gcaacgatgc 191640
ccccaccgct cagtgctcag gcaagcgtca gctacgcgct ccgatacgat gacgagtcct 191700
ggcgcccgct cagcacagtt gacgaccaca aagcctggtt ggatctcgac gaatcacatt 191760
gggtcctcgg ggacagccga cccgacgata taaaacaacg cagactgctg aaggccactc 191820
aacgacgagg cgccgaaatc gacagaccca tgcctgtcgt gcctgaagaa tgttacgacc 191880
aacgcttcac taccgaaggc caccaggtca tcccgttgtg cgcgtccgaa cccgaggatg 191940
acgacgaaga tcctacctac gacgaattgc cgtcgcgccc accccagaaa cataagccgc 192000
cagacaaacc tccgcgctta tgcaaaacgg gccccggccc acctccgctg ccgccaaagc 192060
aacggcacgg ttccaccgac ggaaaagttt ctgcgccccg acagtcggag catcataaaa 192120
gacagacccg accgccaagg ccgccaccgc ccaaattcgg ggatagaacc gcggcccatc 192180
tctcgcaaaa tatgcgggac atgtacctcg atatgtgtac atcttcgggc cacaggccac 192240
ggccgccagc acctccgcgg ccgaaaaaat gtcaaacaca cgcccctcac cacgttcatc 192300
attgaaagtc tctccagtcc atatgttgtc aggacgtgct gtcgttctcc gcttgctgcg 192360
aagcccgttc ttccgagtcg tgtcgctgcg tccagcgtcg cgcccaagat gggaatttgg 192420
gtcttttcac gcgtagcctc ctccaccacg gctgctgatc gccgtcacta aggaccgaca 192480
cggaggatga cgaggagctt ctccccgact ccgcggtccg cgaccggcta cgtagcgcgt 192540
gtccctgcca gtctccgcag ttacaccaca cgtcgtgagc agcgtgcacc tgctgccgcc 192600
actgggcctc ggcgtgctca ggccacccgc cggagcccgg tctgagctcc gacgcaggat 192660
gcgcgtactc aacgtgcgcc ttccagtcca tacagcaaca ccataggtcg tgcgagtcgt 192720
cggctacccg ccgccaggcc agttcccgca tgggaaggct ggacacgccg accgagaggt 192780
caccgagccc ggacgccatc tcttcttcct ctccgtcgct gtcattaagc agccaggtca 192840
cctcctccgc tccgcgtccg ccggtctcga cggaccgcgc cgccgtcggc aacacggaaa 192900
acagcacgcc agcccgagcc gctaaggccg catgcccctg ccgcccaact gaacacgcat 192960
accccgctca actgcgtttt gccacccctg tcagtgctct cgctcgagca ccaccccgca 193020
tctcccaacc tttttccaat aaacgaaacc gacatgacac acgtaatggg tactcgtggc 193080
tagatttatt gaaataaacc gcgatcccgg gcgtctcagc acacgaaaaa ccgcatccac 193140
atcatagaca agttacagtc cacagtcaca tacacgataa acaataccaa cagggtaatg 193200
tttatggagt aaaacactat tgtccaggcc acatgcgtgt atgacttccg caccatcccg 193260
tactgcatgt tccacatgta cgcgctagac gtgtaatcca ctcgcagttc ggggacgcaa 193320
cgcagccaga tcacatcccc ttgcagtacc agacgcaggg ctagcgtctc gaagatcggc 193380
atcacatcta agttccgcac gttccacttt aacgactccc cgggaacgaa ctccacgtcg 193440
tcggcgtgta cgtacaggtt ctctcccacg ccgccataat cggccttcgg atcgaagacg 193500
aaccgactca tgttgcccac gatgctcccc cgagcaaaca acttgccgtt gtcaatgtag 193560
caccggttgt cctcgatttg aaaccaggga tgcttggccg tggacttcca gggccggagc 193620
gcgtcttccc cggctttagt gattccatcg ggcaggcgga tcaagggacc catggaggtc 193680
caaagaccca cccaggcttt ccagagattg ttcatggtga aacagcgtgt ggactgtacg 193740
ctctttccca atttatatcc cagagtagtg acgtgagccc agccacctcc cagattcctg 193800
acgttttggt tgtctttcct gccaattcct cccgtaaact tatgattatc ctagcccatt 193860
cccgataaaa atacacggag acagtagata gagttacgaa taaaccggtt tatttattca 193920
agtgtctcag gagattattg aacgagcgtg gataccacgc cgtcgtcagt tcatggtggc 193980
attgagcagc catagcacca gagtcccggc gcccggtatc agacacgctg acctaccggg 194040
cgccttcgag tccgtacccc gcggcctggg tgttagagtc cgtaccttgc agcccaggta 194100
ggtttcaggt accagctggt tcgtacctgt taaataaatc gcagacgggc gctcacccct 194160
acggtcagga gcacaagaac aaccagagag aacagatata cgagcagggt tctgaacagc 194220
agaccccaat tgtcgtctct catgcttcgc tgaaggtacc agttgatggt ctgagagcta 194280
tagtccatcc tcacctgagg aacacacgcg gcatatttct tggggtctcc ccacctcgta 194340
gacaacgtga tgtccaccat atccacggtg tgcgtcaccg ggtgcccacc gatgttccac 194400
tcgaaatagg ctccgcgctc atcatggtgg tactgctcac cggacacctg cagtctgtcc 194460
atgtaagatt gagagacgat acccacgttc acaaagtgtt tctcggtgaa gttgcccgac 194520
atcctcccct tgaagtacag catgcccata tggaaccagc attggttctc ctccactcga 194580
aagtgggccg atctgatctc cgataccacc acatccaggg gccggggcac cgagtccgcg 194640
agtctcagga acaagacggc caggatcgcg agcaccaaca ccggcttcat ggctccgaag 194700
gtccgctgct cggctccgct caccgctccg gtctggctgc agcagtgctt cgctgagaag 194760
tagcgtgtgg actgaacggt gtttttgaat atatagcgtt tcttggtgac gttgtttccc 194820
ctacgtagta ggcaactacg tgccaaaaga ggcgttacgg tactttccgt actgggattt 194880
ccaaaccggg actttccaca cggcggtttc aacaccggga cttttcacac ggtgatttcg 194940
gcaccgggac tttccgcacg gcggtttcgc caccgctgac gttctcatcg ccgcccacgt 195000
caacggtggc gacaccgtac tttcccatgc ggtttataaa cgtcaagagt cacgtcagtc 195060
gcccaccccc attacacggc gatatcccga tagggcatga ggggacccgg gtgtcgcgac 195120
atgtcgacga caggtgcgga ttagtggtcg tgtcgcgaca tggacgtgca gggggatgtc 195180
tgtcgcgata gagttgatgt gacagcccgc tacacctctc tgtcgcgaca tgcatacaca 195240
acgggccggc ttgtcggcga ttgtcgcgac atatcgttat cagttagcga ccggagttgt 195300
ctatcgcgac atatcgtcga ctatcgcgac agaaaaaata ccgttcgtag agaatgccgt 195360
gttgaaggaa cgcgctttta ttgagacgat aaaacagcat caggagccac aacgtcgaat 195420
cccacgtcca gtcgattcgt atgttatgct gcacagcaat gctagaataa caaccagcag 195480
ggtaatcccg caacataaat acaaagtcac agcgaagaat ccgtgtcgtt ctatcaagcg 195540
aaacgcgttc caaacggccc cgtcacagac gcagttattc ataagcgtta acaaccggtg 195600
gctaggatga atatccaaat cacagggcag tagccgacgg actcgttgac aggtcagcct 195660
accctcaagg ttcctatcgt tcggacggga tttgtgcgtt ttaggcctct ttttcgccgc 195720
ctgcaagcat tggtgcgcaa agtcctcacc cagctgtttc cagctatcat ctgcatctgt 195780
gcagtcccct gtatcgttgt aacaaacggg tctgtgcgac ttcgttctcg gaacacaagc 195840
ttgttgtcgc ggagacagag agagaagggt tttcgggtca cgcgaagacc gctcaccggg 195900
ggtcggcaac gcacacatca acagaaaacc gagacgaatc aagagatcca tagtgaagga 195960
gtgatatcga cgtgcttacg aaacggcgat tatatatgtt ctcaacaata ccgccctacg 196020
ttgtatgatg taacgtgtga cgtgagtctg atccaacact gaacgctttc gtcgtgtttt 196080
tcatgcagct tttacagacc atgacaagcc tgacgagagc gttcatcggg gcatgaagta 196140
cgcattacac aaactccata tatttgttac gatagaatac ggaacggagg aggctttcgc 196200
cacacctatc ctgaaagcgt tgcattcttt atgataggtg tgacgatgtc tttaccattc 196260
ccacggctgc tttgcgtgat gatgacattc atcatgtatt tccattcaca catacctttt 196320
gtgcatacgg tttatatatg accatccacg cttataacga acctaacagt ttattagccc 196380
ttgacaggat aggtcaaaag attatatgta ggttttccgg taaaccgaat tgtgatattt 196440
ctctgcagga aatagaacag cctggtacct ataaaacgga caatgcagta ctgtagcagc 196500
gtaaccaagt aggtccacat gaacacgtac aaaattatgg taagccatcg tttttcatac 196560
cacagcctgt agctgtcgta catgaatgag gacggtcgag gaacccaggg tagttgtaat 196620
tgggggcgac attcgtactg tccagaagac aattgcacgg gtttcagtga gatgagtact 196680
ttagcgatgt cggcgggggc gctacgtttc accgtgacgg tgagaacttg accgtcgttt 196740
tgtatttcat gaggcacgtt atacaagcca ctggtatcat gaaggatgac ctctgatgcg 196800
atgtgaggat taaattgtcc ctcaaaccgc caaacgctgg tcatgtttcc accgtcaatt 196860
acgcagctga cggtgtgaga taccacgatg ttggacttag gtttgggggc taattgcctt 196920
tttacaaatt cccttctgta ttgcaggtcc tgctgccact gcttttccgt gcggaaagtc 196980
gccatgtctt ccacacgtgt ggcgacgata gacgccacca aggtagctac cagaagcagc 197040
tggatccgca tggcattacc gtatgtcaat tagaaagttg agcggacacg gttatcgttc 197100
ctggcggata taagtatata aacgcgagtt agcctttccc gtccgttttg tacacccgtt 197160
ccccacacaa atgacgaata cgaccttttt ttttataaaa ataaaccacg tgtattatat 197220
aaaaacattt acatagaaaa gagacacacg gatcaacata aggacttttc acacttttgg 197280
ggtacacagg cgtgccaccg cagatagtaa gcgctggata cacggtacac agtcctggcc 197340
agcacgtatc ccaacagcag caccatcgcc atacagatgg cgatcacgac cccgagctct 197400
aagtgtctgt attcatagtg tagtcgccgc aggttatcca ctgaattccc gtaactgaaa 197460
taacgtatat ggtaccgagg ctggcaccac atgggtttgc atttggtgca cggcaccaaa 197520
tgcagagtga gatggtccaa gtccgtgggc acccactggc gcaaacggaa tacggcttcg 197580
gtggtctcca cgaggcactc cggggcgtgc agacggcccc actttcgtcc gcgacggccc 197640
gaccagccga cccgagccac tatccctttc tcgggataga acgtaccctg tacacgccac 197700
acagcgtcca acacgccgtc cttgacgacg cagctggcct gatagctgga cacgttgtta 197760
agcggcggaa agcgaaactg acgtgccggc ggagccacat agttcggttc accgtgttgt 197820
cgcggttcgt cctccctata gtaatagtag tcgtcgtcct cataggggtt gccggcgtga 197880
gccagcgtta cccaacagca gcccaggccg acgaggaggc gcagccaccg cctcatggcg 197940
gcttcgccag tcaatcgtct ttagcctctt cttcccgtga ggtccttccg gtggcgcggt 198000
gccgacctcg gacccaggga cgtatccacc tcaggtacac acagcaggct acctggacac 198060
cgaagctgaa caaggctacg tgtttcacaa actgcaccag taccacatag aggaatgtca 198120
ggtagcgtct ctccgcaaac agccgttcca agtctgaggg cgttacccgc agcggcaacc 198180
agggcagcct ggacgccggc cggcaatgga gcacgctccg gttacaggca ctgcaggggt 198240
aaacggttaa catcacgtaa gagagtcgtg cgtccacctg tgggagctca gtttcgtaac 198300
gtagagcccc gtcattttcc agctggggtg cgccgacctt gaaatgggtc gcgctccgct 198360
cgttacccca ggtgccgtag gctctcgggg ccgtatcgga gaagttgcca cgcacaagcc 198420
aggcggccac gagtaccccg tgctggacgt aacattcgga cacggaactg gagacacggt 198480
agccggacac gtccccaaac ccgcgagggt actggggcag acggacggac ttgctatttg 198540
acaacggaca gatacgagac gacgaggacg cagacgactc gtcgctggac cacgacaacc 198600
ggagcgactc cttggagcgg ctcgagagta cacttactgc gatcagacac cagtgccaga 198660
agaaggaaca ggtggacggg gaccacagga tcatagccgc cggcaccgcg gccggccgca 198720
ggaagccgcc cggcgcgtcg tctgtgtgcg ggagccgaaa caccgtgcct ctttatatcg 198780
tcccgacgtg acgcgagtat tacgtgtcag gggaaacccc cgtcacgacg aacgtgattt 198840
gtaagtgacg cggggtgctg acggggttcg gcccgagagg tgacggagcg cctcacgtca 198900
gtatgatgtc cgatccgcgt cagccccgac gtggttgtgg tcaccgaaac ccacgtttat 198960
atggacgttg agagcagcgc ctgaccacat gattcatcat accatttctc ggaatcgggc 199020
ccatgccggg aaagcacatt ccttttcagt aaacaacaat gacatcataa caaatcattt 199080
tattcgcgag gtggataata accgcatatc aggaggaggg atcgggtgat gacgcaggcc 199140
ccgcagaaca gtccgaaata aatttttagt attgccccat agtcgcctag ataccagagg 199200
tacgttaagt tcatcaaaac gcccatcggc gtcccggaat cgtataccgg gcacacgaag 199260
cgttcataac aatcccggga ggcgagtgtt agggtagcag agtagtttcg gggtcggttt 199320
ccttccggcg acgacagttc cgtgggcagc agaatgtaca gcgcctcggt agctgtcgcg 199380
gtgccttcca cgaggatggg ctgccggtgc ctttcgtgat tttccccgtc gtgtagccaa 199440
gccgaggccc gcaaagtctt aggcgagggg aattgtccat agagtttcac cgcacccttc 199500
agtacatggt tctgaataac acagccgcac gtgaagtagg taggttctct cgtctcctcc 199560
gtggctgccg ccaccactcc cagccaccac aacaggcaga tcgccagagg gttccggagg 199620
cttccccggc gtagcatggt tttgggttaa agcaaaaagt ctggtgagtc gtttccgagc 199680
gactcgagat gcactccgct tcagtctata tatcaccact ggtccgaaaa catccaggga 199740
aaatgtcggt gcagccaacc tttcacatac agcccccaaa acacttgaat cactgccacc 199800
atcatcagcg tatactgcgc cgacttaatc gtgagcgcgt agtacgccat tagacggcga 199860
tcttcgaaca atagtcgttc gatgtcctct aacgagctcc acaggggaac ccaaggcacg 199920
aggcaccggg gttcgcactc tacataataa gtttggcatt ggtggcaggg ggaaaagtag 199980
aacaacacga gttttgtgcg ttggggaaca cgatagtccc ggagccagta gcgttttgcg 200040
acgaggcttt cggagacgtc ctccaccggc gtcggcactc gatccgcgta gccctccagc 200100
gtctggtagt acacccgggg tgtcggcgtg ggcacggaca ggttcccgcg cagggtccac 200160
agagcctcca gtcgaccgcc cgatcggagc acgcagcgcg cctcggaata ctctactcgg 200220
tactccgaaa catcggacag aggcggtaac ggctccgtct ccaccaaggg cggaggttca 200280
tcgaaaagag tcaaggataa ttcaggcata ctacccgcga ccggggccca gagggctaga 200340
ataagcatta caaggttcat tctgtcttac aagggaaggc tgttaccctg tctagactca 200400
aaagctgtaa ggctgtctta tagcatgtag tcttgcacgt cacggggaac agggtggtga 200460
tctagtgacg tcgggagaac acggtgtttt agggtgcggg ggacaaagga cagtacgaca 200520
gattaggtga tagaaacgtt tttttttatt tatgaaaaag ccagtgtgcc gtgcggccta 200580
gggccccggc gtagtttgga taccagatgg gggccgtcag gggtactacc acgagcagaa 200640
acataatgac ttggtccatg tatagcagca tagcggtgcg cagcaggtcg ccgtccgtgt 200700
agcaatttga cggtgagcga taaagcaccg ttaatgtgtc gcggataagc acgatcttga 200760
ggccgtagat gaagctcaca gtcagtgcta aaatgatgcg ttggtatggt tcccaggact 200820
gcacggcgat gaagagccag agtatgggaa gcatgaagct tagcaaacag aggatggcta 200880
accgtcgttg catgttccag gccatgagcc aggctaggcc cgtacaccag acgcagagca 200940
tggatgacag gacataggcc tggattacca cggtgcgatc gaaacacagc ccgatggtgg 201000
acacggatat cgtagtgagg gtggtatata ccatgaccag catcagggtc ccgggtcggc 201060
gccgacgttc cagccagtac gcgtggcaac gcagagcgca gggtagcagt gtgctccaga 201120
agggcaatgt atcgcgcagg tagggggccg tcacgcgcca cggtatgagc atgaaaagga 201180
tggtagtggc tatggtggcg ctggtctgga acacgacagt gccgtagaga cgtaccatcc 201240
agagaaagtg ttgaacgctc cgcagggtgt cttcatcttt ggtgattacg gtgactcgac 201300
ggatcggcgg tggtgacggc ggcgacacgg gtgggggttt ctctttctta tggccgagtg 201360
gctcgccttg gtgaaactgg atctgtacca tgacgggtgc tcgacgaaca gtcgtggggg 201420
ctttaggtac ccggcaagtt ttatagagaa agggggacga tgggtggtgg ctacgagcca 201480
ccgccacctt cgcaatacga ggatctgaag gcggcaaaga cggtcgtcca gggcaggcgc 201540
cagaggttgg gactgagcac gatcagcgtg attttaaaca tggtcaccag tcctacgtag 201600
atcagcagcg agccgcgtaa cgtctgagca gccggcagtt cgtcgcggat gtaacgcgtg 201660
ccgtagaaag tcacggtcat cataaggaag acgatggcgc cgtagccgta gagtagaata 201720
cgctgatgat ggaacacggt ctggtcgccg ataacccaga gcgtgatgaa aaaaacgctg 201780
gtgagtaccc gtgagcatat gagctcccaa cgcttagcgc gaaagctgtc cccaaccatg 201840
acagcgccgg tgcaagctat ccacagcgtg aggaccagtg tgtagtcgat gaggatggcg 201900
ggcaggtcgg agcaccaggt gtagaaaacc gtggtaacgg agaggaggcc tacgtagccc 201960
atggtcaata ccacgtcgtc ggggtgcctt tcgccctgta tcaagaccaa acaccagaga 202020
agggaggggg caaaaaccag cagcagaggg gaagattcat gttgacatat gttgtgggaa 202080
tcggggatac ccagccaaat cattccgcag aaagccgtac tgatggcgat gtgaaagacc 202140
actagggcgt agacccggac gaggacagca aaacggcgca gccacataag gccgtggtgc 202200
agctgcagga gggaagccca ttgcggcgaa tgtagcgacg gtagcggcgg gtccatgagg 202260
cgggtgatgc gcccgagtga acgggtgagc gtctcggtgg agtcttctta taaaccagcg 202320
gagctcaggc agccttgctc tggaacgtcg cagtggtggt gttgaggatg acgctgagcg 202380
tgccgttgtc aatcaggtaa tgatgatagg tgccgagctt ggccaggtag ctgaacattt 202440
ggtcccagcg tgccgaccac accacgggcg tgagcatcag gagtgtggtg tgatagatta 202500
gtgtttcggt ggcgtaaagt atcagcgagc tgcggatgac gtggctcacg ggcattttgg 202560
tggcgatgta gcgcacgtct tggaaaagga cggccaggat gcagcccacg aacacggtgt 202620
agagacacag caaagtctta tgtaaccagg tgtaagtaga agccaggacg ctgaccatca 202680
ccgtcaaaag tgtggaggta aaaagcgcgt cacgccacac ggagctgaga cggtgctccc 202740
aagccacgcc gttgcaggcc acgaacaacg tccacgttag gatgaggcta gaaatgccga 202800
tgggcgctgt ggcgcacagg ttgagcccgg cggtggtgaa cgagagaagc gccacataca 202860
gcgcaaacac caggccgttg ctggggtgtc tgtgatcggt gagctccagc gcgcccagaa 202920
ccaatactgg tgtgcagcta agcaatagcg gcgagggatc gtcgctgcac ttgtagccca 202980
gcgaggggta acccagccaa accagcgcgc taatgagtac gctgaaagcg gtttccagcg 203040
tcagcaatcc gtagacacgc atgacaatcg cggtccgccg tagccaacac acggcatctt 203100
cggaaactgt ggacgctgtt tccgaatacc gggaggagat cgtgcttccc tcttccaagg 203160
atcggaaagt agcgtccgtc gtttccgcgg acgcggcttc cctggtacgc tccgtttccg 203220
acgacgcggt ttcccgctgc gtggaaactg tctccatgtc gggaccgcag cgcccggcgg 203280
cgtatccgca aggtctcgaa gctacagctt gtcagaggaa aagtaggttt gcaaaaaggt 203340
gcgcagggtc atgattctca gcaccatcag cagagtgaaa accagactga gaaacacctt 203400
gacggccgcc aaaagcgcgc gttccagcgg cgtctcgtag cgtacagcca gggccgcttc 203460
gtggaaatgc gagacggcta gacaggtaat gagcacgctg aaggacaaga cgatcttaaa 203520
gcaccaggac caaccacgcc tcaagatgac caccacgatt gccgtgaagg tcaacgtgat 203580
caaagcatgg acgaccacga tctgacggcg gacggtacgt tcgggagcca acaacgctac 203640
gccggtgcag ctgagaaagg ccagtaaggt gaacaacgcg gccgagatga ccaacgtacc 203700
gtccaggcag agacatatca cgatcaacgg cggcacgtga agcagcgtgt aaaagagcag 203760
aacgccgata ttgctgggat gcgatgtttc gtaacagtga atgaagatca ctgacgtgac 203820
gggtatgaca aagacgaggc tgggcgagga ctccgtgaga cacagacgag aatggtgaaa 203880
ccacgtcgcg ggcgccgcgt agcagaaggc gctcaacaac gcggtcaagc cggccagctg 203940
ccaacccacg gcgccatagg tgtgcagcgc cacgcggcaa cagtcgaccc aagccagact 204000
gcgggtcgcc agccgggtct cttggatccc ggggggcacg tagatgaccg tgccatcggt 204060
gggtacttga aacccttttt ctcttctcat ggtgcgctgc gttctctgga aacggctgct 204120
ctgtccgaaa accagttccg aacgaaaatc tagggcgaga gggtggacaa cggcgtcgac 204180
gacgaagcat gggacaggtc gttcggcgtt aacgtcatcg cgtcggacga cggtagttct 204240
aagagacgta gatcgctcag caggtcctga cagttgcgga ttcgcaagat cagaaaaaaa 204300
agggaaatga acgtaataaa gagctgtagc gacgtatgcg ccacatcgcg tggcataaga 204360
acgtgacgga cgaaaaggac ctgctgcgaa aagtgaccgg cgaagataag gcccaccgtg 204420
ctgtagaagc ccaaaagcag ccgcaggggc caagtccagg gccgcgtgaa gacgatgaga 204480
acgttgacca gaaagaccac gacccagacg ccgttgatga gggtaaattg atcggacagg 204540
gtgcagttgt cgcgacagat gaagactact tccgcgcaga gcaaggtgat gaccaacgtg 204600
agcacaaacg acgtcaacac ctcgcggggc tcctggcagg cacacgtgac acctagcgcc 204660
gggatgtgcg ccaggaggcc ggcgagtaat agcaccagct gtcggaacgg acgacggcag 204720
cgcgggtgcc ggtttcgctg agcgagaacc ggtcgctcat agcggaaata cacgaagagc 204780
gcggaggcca caggcaccag gaggagcacc tcgggcgccc agacaacgtg acaaggaaag 204840
cccggacgcg acttgagagt cgctgtaggg aagaccagag agaagctacc caagacggcc 204900
accgccgcgg agatttggaa gaggagcaag ccggcgattc ggacgacaac ctcgaagcga 204960
tgcacccagc ccagcacggc caccacggcc gcttcatcat agtcgtcgtt gttgccgctg 205020
tcgaacagcc gccgaaacac gatctgtcgc tgggtcgcgg tgggaaagcg cagacccatg 205080
acagccggag gctatatgac cgcgcgtcta agacgcgaga tccgtggggg gacttttaga 205140
tgtttgggcg gcccgcggtt ctaacaggct tgattggtgg agacggccgg cgcggcgggt 205200
gggggaaacg acgagttttt ccgttacgcc atggttcgcg tgaggtttct ctgtacctcc 205260
cgcaaaaggt cacagcccga aatggaggcc gcgttggtgg ccccggtggc gcgtgacgat 205320
aaccaggtca tccaagcgat gagtttgtct aatgagtcct cggtggtgaa gaggatgaga 205380
atgagcaggt acaggtacac caggttctca tagagacaca aggtgagcag gtcagcctcg 205440
gaccacgcga tctcaaacag gcgcgtggtg tcaaagaccg tgacgaccag catgaagctg 205500
agcgccatgg cgtaatagcc caaaaaaagt ttgtgcccca acggtacggg ctgcaggtaa 205560
agtgcgatca agaacgcgat aacgccgatc acaaacagcg tgacgatgac ctgccatcga 205620
cggtgattat ggccggctag acccgtgacg cagctgcaga ggctaaaaag cacgcaagcc 205680
aagaggcccg agaaggtcac tagcgtagag gaggagcagg cgctggccac gatcaccgaa 205740
agcgtcgtga gcacgctata aatggtgagc aggccagggc tcggtggcga cgtgaacgat 205800
ccttcatcgc gtttgccgtg cagcagggcc aaacagatgg tgggcaccat caaacttaag 205860
ggcggcataa agccggtgca acagagaaag acggtgcctt taagatgcgg aaaagccagc 205920
accaggccca gacagagcaa gaaggtgcag gtgccctgca cggccacggt gctgtagacc 205980
cgcatacaaa gtaaaaagcg acgtacgtcg ttcgtcgaca cggaggaaat cataatgact 206040
ccgcgcgagg gtcgcggggg tgggggcgcc caggccgtcc cggtggcctc tgagttcgga 206100
gacatgacgg cggtggcgat caaaaggcgc gtatgagaaa ccgtttatag agtgtaatag 206160
aatcaccgtc attcccacac ggcgttcccc cataaagtca cgtaacactc gagtaagcgt 206220
gaaaaagctt tattgttgaa taaaaaacac gagtacaaca ccgagttgcg gtgtcctgtc 206280
tgtctactgg gtggggaagg ttcatcgtct gtctctagag ggaaggtggg gaatgtctaa 206340
gcgagcggga gcgtgtcatc tcccccatct ttttacaaca agctgaggag actcacgccg 206400
tcgatgcgtc cgccgtgttt ctcggcgtac tgctgcaccc agacgtggcc gctaaatatg 206460
gcgacgctca tgtttaggag actcatgacg atggtgtaca acacgacgct gacacagacg 206520
ctgtttttag acaacgttcc acgctggtag atgagatcca gggtctcgta aataagcacg 206580
gccgaagcgg cggtcaccac caggacgtag agtccgctgt agatcttgct gacccacagc 206640
acgggcgaaa agtaaagcaa taggtaaaag acgatgacgg accagccgta gccaatcccg 206700
atgactttcc agcgcgtggg attgttgccg gccaggtagg tgagaccgct gcagagaacg 206760
aaaaagacca tcaccagggc aaacgacaga ccgatgacgc gcctttctcc gcaaaagccc 206820
gtgcacacgg tgatgccggt gttgatcagc aagcacgcca ccgtgagatg agcaaaattg 206880
gtggtgtgtg ggcgaaactc ggcgaaaccg cgtagcatag ccagcgtgga cacgggtacg 206940
atggaggata gggctggcac tatgccgttg gcgcactgtc cctgcacatc ggggaaggcg 207000
agccaagcca gcaagcagac cgtgagggta caagccagct gccacacgag cccgtgatag 207060
acctccatga gcagcttaaa gcgtttcaac cattggaaga gctgctgttc ggccaccagc 207120
gcgtggctgc gatggagcgg cacgatggtg accgtcggcg actcatggtg ttcggaaacc 207180
gaggcggtgt cgcccatgct gccgcttacg accgctgtcg gtctaaggta ggcgtcgatg 207240
aaacagtccg tcttatcagc acccggttac cgcggatttg attgacgtca cgagtgtggt 207300
caaaccgtgg cggcaccctg tatccgaccc gtcgtcatgg gctccacaac cagagcctca 207360
gaagatggta catgccgatg aataaagcca cattttcgac atagaggcgt agcgagggct 207420
gaaaactctc cgggaaagaa ctctgacagg tgatcaggga cagatcgtga attagcatca 207480
gcgtcaccgt caacagcgtc gtcgcgtgta aaccgagaaa gaacggggcc gcggcccgca 207540
gcagccaaag tcccagcgcc gtagcgcaga gcagagacag gaccgacggt agccacagcc 207600
gccggagaga cgcgccagga tcgcaaccca aaagcgaggc ccccaggcag ctgagatcta 207660
ccgccagggc gagaagagcc gcgccgacaa aggcctgcgg cgacggctgg cacatcagca 207720
aggtcagaaa ggctagcgcg tgcggcaggc agtaagccaa caggagtggg agtttgcggg 207780
gacaacggtc gatcgacgga ccgcgtagca gcaggaacag gcagccgacg ggcacgacga 207840
ggctgagatg agaaagcggc ggtgggtcgt cgtcccgtcc ccgctcgcat agctcggcca 207900
ccggtggcgg catgagccac cagctgagca cgctgagggc gacggtggcg gtaagctgga 207960
aggcgacgag gacggaggcg cgcagccata ccgccagcct ctctaggtag gggactacct 208020
cctcgacggt ccattctagc gggacgacat gaagcatggc gacaagcgcg gctgctgtga 208080
aaacgggcac ggttttatag gcattaggac ttccccgtcg tactggcggc tgtcaaagtc 208140
ccgttgtcca aaggcgcgcc gtccgaaaga ctaatccaac ggggacccga gagcatgagc 208200
aacaacgtga gaaagatggc catgctgtcc aggtagagac agacggcgtg acggatgcat 208260
tggttaggtg ggcagaaaaa gatgaccata agactgtcgt aggccagaat acccaaaaag 208320
aagctgatag agaaggcgca caacgtcacc actatcttct gcagccaatc ggcgtcgctt 208380
agcagagcga gcgtgaggaa cgaaagcagc attaccacgt agacgcagct gatgcatttc 208440
cagcgacgtc ggtcacggcc acctagaaac gccagccccg taaaggagat aaacaacgcc 208500
agggtcatca cgtaggaacc tactagtacg cggctttcag agcacatttg gaagatggcc 208560
gccgtcaggc tgttggccaa cagatagatg aaaagcaccg tggcgttact agggtgttcg 208620
ttgcccaacg tgtacgtgat gaacatgcag acgatgggca cgagcacggt gagaaagaag 208680
ctgtagttct cgacgcaaaa gttgcggttt tgtgggaacc ccaaccaaaa aacgcttccc 208740
aagccgaagc tgaaagccag ctgaaagatg aagatggcgt acacgcgcag ccatacggtg 208800
aactttttga accactcgag agcctccatg cgggagagca gcagcgcgtt agcctcctgc 208860
gcctgcatgg tggcgacggt ctcggcacaa agccgctgcg gcgcacctac ccttctctta 208920
tacacaagcg agcgagtggg gcacggtgac gtggtcacgc cgcggacacg tcgattagga 208980
gacgaactgg ggcgacgccg ctgctgtggc agcgaccgtc gtctgagcag tgtgggcgct 209040
gccgggctcg gagggcatga agtagagcac ggagacaaag aggtacatga ggtccatgta 209100
caagcagagc gcgcccggga tataactctc atactcgatg tcgtgcagga tgtcctgcgt 209160
atcgcacacc accgaggtca cgatgacggc caaaccggct atcatcacca ggatctcact 209220
taccgcctcg ggaaaaagag aaaatacggc gaacagtaag agaatcagcg tggatgcgcc 209280
cgtcaatagg gaacgctgta attccacgtc gcgggcaaac agatacgtag cgagcgtgag 209340
gaaacaaaat agcgtcactg tggccaccat ggcataaatg actgaacgat gactaaagtg 209400
gaagcctgac gccgtgacag ccacgctggt aagcaacgtg tacgtcagta agatccatac 209460
gtttttggga aagttgggct cggcccaacg caacagacct aggcacacga tggagatcat 209520
taagcaagac agcgtcagac gcacgctgga aaagagctgc tccaaccggt gcggcaacac 209580
cagccagcaa aaggcgcaga cgctcataag gatgaggcat tgcacccaga taaggatgta 209640
gatgcgcagc aggaagaccg accgggctat ctggacctga ccgcggagcg acatggcggc 209700
aacgccggcg gttatcgccg agattcgtct aaatacacga agcgaactag aaaacgcaca 209760
cacgtgattt gcaaaaagaa agcagctgcc ggcttattat tttattaaaa atttatctgt 209820
gcagaatcat aagtttatga tgaataaaaa cggggaaagg gaatctgctt ttagggaccc 209880
gggtctggtc cgtcgtctcc catctggtcg ggttcgggga tggggacctg tttcagcgtg 209940
tgtccgcggg cgtgcatggc ttttgctcgc cggccgcgct gtaaccaggc ctctttctct 210000
gtggtcggcg agtcttccga cgggtaggga gcctgggagt ccatcgcttc aggcccaccg 210060
ctcgttccct cgaccgtcgt gtcgtcctcg ttttcgctat tacacggggt ttctggagta 210120
tcgcctatac ggttggcgat tctccggggg cggccgctct cgtcctcgtc gctgctatcg 210180
ccgcccggta attcgacgcc gcattcgttg tacggaacgc ggcacatggg cggcggaaag 210240
aacttgggca tgcgaaagca gcgttgtcca tccacggtct gcgtggtttc atcgttatcc 210300
tcccataatc ccccctgtag cgccggcagc gtttcgacgc tgtgagaggg gaaggcccag 210360
ttctggttgt cttgcagcgc gcccgtgggc agtaggtccg tgcggcccca tgcgctgctg 210420
ttgttgggta ccttgtcagt gccgcgagta ggtcgcagaa accagtccag agcgctctct 210480
agctgcgagc gtgtgatggt gcccagtgcg ccgtgccagc gcagcacgtc tcttttcagc 210540
gtgtggtgac agacgggcag ctcctccaac cgacactcgc cgcgcaatcc gcggtcgaag 210600
cggcagagac cacgcagttt aagcagaccg cacttgagaa acatgtgaaa attatcggca 210660
atgcgatata ggtccgagtc ctcgatcttg tgtaggtaga ccacgccaaa cttgtcgagc 210720
agcaccaggc cgctgggcac aaaaggcccg taggccaggt aatagcccac gaggccgacg 210780
acgtaccact cgcagcacaa gcgttgacga ataaagttca gaagatcgcg aaagtccgcg 210840
gccggcatgt ggtcaaaagg ccggcaggcg cgcaggccct cgatggagcc cagcatgagc 210900
aacggctcca cctcggtgcg acccggcgtg cggatgacca ggttgagacc gctcatttcg 210960
cgggccgtct tggccacggc cgcagcgtca gtggggtcgg tgcagaggaa tttttgcaca 211020
tgatagcgcg gttcggtggt ggcgaacggc gtttgtgggt gccgatacac atattcgcac 211080
cagagtaggc cgttcttgga aaaggctttg atatcactgg ccacctcgta gagcccgtcg 211140
gtctcccagt cgtagacgta gacggtgccg taatgactta gcatgagcac gcagggcagt 211200
tcctgcgcct gcttggtgtt tcgtgttaga tcgctgtcgg gtggacgcac ggctagtaca 211260
ccgacggctt ccagggtgtc atcgcagcag agatagtcgg cggccagaga acgtgcgtaa 211320
atctgcggga tggcggcctg ttcgcgcatc actaggaacc agttggcggg gttgcgcagt 211380
gctacggtgg ttccttggtg gcgttgcacg taggttctca gcgccggagg atcgtactgg 211440
cgcagataga ggccttgcag catcgataac gtcttttgaa agacggtgtt tctaaattga 211500
aaaacgccgt agtcgcagcg gatagcatct tcgcacgctc gtcgcgctgt cggagatagg 211560
tgccccaggc ttcggcggcg gctttggtga gtagggacat gccggcggag ccgtctcgac 211620
agcgagtcgg ataaagcgcg ctgcgcgaaa gcttaatata ggagcagcgt cagacgaatc 211680
gcggctggtg gcccgggggg tgggacgcgc cgcctacaca aagtgctccc gaaaatcgaa 211740
actcttgacc cactccggag acaaatccgt attcagattg atgcgtcgag cttccacttc 211800
ggcttccgaa acctcggcct ccgtccggta ggcgttaaca atacgctgac ccaggtgcca 211860
acgctctttc tctgccaaac gccgttgctc aaaccattcg tctacgtcct tgaggtcaaa 211920
gacagtgtcc tcctcaaggt caaagcctag gtcttcccac tcgtcgtcat cgctctcgtg 211980
gccggcggcc atacgcgcgg caaccgcgtc ttcccctcct cttctttcaa cgttgggtac 212040
cacgttgttt tcttcgggtt ccataggttc tgcgccgctg tcgtcatcat cctctccctg 212100
ctcctcatcg tccgccaagg cgtcgtggat tacctccagg ttctgattgt cgggtacgac 212160
gtggttatct tcgtcgtcgt cgcgtggcat gggcggcggc cgacggcgga cgaccggcat 212220
ggcgcggccg tcgtttcctt cgtcttcctc ttcaccgtct cccaaggaac gcggtcgacg 212280
acgttccgcg aagtcgccgc ggaccacgcg cgcctgccaa atggtaaacg cgtcccaacc 212340
gtcccagtta ttgagcattt cggcgcgaaa acggtcgcct cgacagagcc agcgaaactg 212400
ccgcgcgtag tcgcggtcta cgccgctgtc gaacatggta aagtgcagac gcgccgcctc 212460
gcccatgtgt acgcagcctc cgttgcgttc cagcctggcc gcgcgccgta gaccgtgttc 212520
gtagcggcga cgcacgtaca ccttcatgag gccggcgcga aaaagttcct ctaggctgtc 212580
ggccagccgg tagatttcac cggctagacg ctgcaggggc ggcgagcggt ccagatgcga 212640
cttgacaatc accacgtaaa aacgacagaa acggtcgaag atgatgagga aggacgtgtc 212700
aaaaaaacca ccggcgcggt aagagcccac ggcacccagc aggtaccagc ggcaacgcag 212760
ttgcagcgtg acgtacattt cgcactcggc caagcgggcg gctggcgcta cctcgaaggg 212820
ccagcagtcc gtcaagcagc cgaaactggt caggagtttc aacgttttgg catggcgtcc 212880
aggtgtatga aagttcacgt cgcgtccgtg gtgttcgcca acgcaggcgg ccaacgcgtc 212940
ggcgtcatga ccgtgacgca gcagcatcgc taccacgtcg tgcggtaccc gcgtagcaaa 213000
tggcgtctgt ggctgacggt atacggcttc ggtgtacatc ataccgtaac gcgccagctc 213060
gtccagatga cgcgcgcaca gcagcagaat ctcttgcgag ggttcgtaga tgtagaggcg 213120
cgtaccgcca cccatgcaga gcaccagctc cgtctcttcg tagtgatctt ccaccatgat 213180
cacgcacttg cctagcacga taaggcgttc ggggcaacaa atcacgtcgt ccagcagctg 213240
gtcgcgtagc tccggcatgg tgctgccggg ccgtacctgc aggaaccagt tgtgcggaat 213300
gccgagcgac agcacctggt cgacgtggtt acggacccag tcgcgaagca cgtcggcgct 213360
gtactggcac tcgaagatgc cctgaaagtc gcccatgacc cgcagaaaag tttcgtagcg 213420
cgtgtggcaa tagaggaatt catcgtttcg cgtaaacgtg ggagctccgt cttcccaacg 213480
tgtacgccac atgtcaaaag aggccgccag ctagacaccc cagaaaagaa gcagagaaag 213540
agacttcttt gtgcgacacg ttttattctg cgtcctccgc tcgacgttca aatctggatg 213600
tactcgcgca cacccgtcag gctctttaag ggaaaagggt ccgagtacgt cactaaccgc 213660
gactgatgca ccagggcggt aatcacccgc tccgcgccct cgcgcgtcga cgaacgcgtc 213720
gtcaccaggc aatgcagccg cgggcccgta tcgtcctgat gaccagcggc ctcgcgctcg 213780
gctgcttcca caccgacaat gtcgggatcc aacacgtagc tctgcgagtt ggtgtcgtag 213840
cggtgtagca ccaacgtgtt ggggtccaga cgctcccacg cgccctcgtg cgggtcaaaa 213900
cgctccgtta aacagagcca gtcatactgc tgctgcagaa tacgccgctc gcgctcgcgt 213960
cgctcatcgg gcaacgcggc gtcttcgttg aagagaatgt cccgcttgtg gtctacggca 214020
cgctcgtggt ggtgcgggca caggtgacgg tgttccatac gcgtctgacg ttgacgctcg 214080
cgctcaaaac gccggtgtcg aaagaccatt ttcagcaacc ccatgcggaa aaactccgtg 214140
atggtgttgg caacgcgccg cacatagtgg ttggggtcgt ccatctggat ggcgtacacg 214200
gcaccgaacc agtccagcag taccagcact tcggccacaa aactgcgtcc cggtcgcgga 214260
cgtcccgtca cgcctagcac ataccacggc gtggccagat tagcacggac agcccaccac 214320
caacgacggc tctccacctc ggtgagcgca caaaagggcc aaatgcggtg taactgctgt 214380
accgttttca tcaaccgcat aatcaccgta ccgtaacccg gtgtatgcaa ctttacgtcg 214440
caacccagga ttcgttcggc cgtggcgtac gagccctcgg gcgtggtgtc attgagaaac 214500
aaaacatgca tggtacgcgc gcccttagga tatcgtcgcg gaacgggtac cgtcattctc 214560
cgcagagtgg tgtgaatcac gtcgcgatac gcaatctccg aacgtgacac accgtaacgt 214620
gccagttcgt ccaggttgtg cgataccaac accatgtact tttcacgagt gtcgtaggcg 214680
tagacgcgag aaaagcgacc cataaaaacc acgtacggag tagccaccat gccatcatgg 214740
tgatcgcgac gtggctcggg caacaaaata acagcgtatc ccaacggcgt caacggctcg 214800
cggcaacaga tgagctttga cgccgcctgt ttggcggcgg taatgatccc gtcctccgta 214860
cgtaacatca catgccagcc cttgggggga cccaaggaca gacagcgtcc ctcgttacga 214920
tgaacgtaac gcgtgatttc cattggctcc aggcaaaaga acagttcctt aaaatcccgc 214980
aacacttgtc ggtataacgc catgggatcc tcggccgcca caggcagcgc ggggagctcc 215040
ggcggcataa ctgcagcgcc gtcagggcca gaacccgcag ccggatccat cattgagcga 215100
cactctcagc cggacaaccg gcgtcactga cagaagccga gccaaataca gagaaagcaa 215160
cgctacaccg tcaccccgct cccaagcgcc gcggaaagtg ctccgatttt tcaccgtcgt 215220
tcgcgacgtt gatttgcctc ggtctgagaa ccgacctagc gttcggaccg gtgcgcagaa 215280
acagccggcg gtccgagcca ctgagcggtt cacagccccg gccgccgata gttaccggag 215340
agacgttcga gctgcaggta catcagcgct tcccgcttcg ccaccccgcg cccgccccag 215400
tttatactct ccgacgcccc gtccaacgcg cctgtggagg gccaatcgga ccgcgggagc 215460
tctccaagtg gatgacaggc acagccgagt gcccgaccgt gaagagccct catccacctg 215520
aacagaccgc taaccgaagg accccgagtc gcgtccgtcg gtcccgacgt ccgtcgccat 215580
ctggctccct gctgttggct acctctcgga tttcaaaaaa gagcacgtgc cgatgacggt 215640
gcacaggaaa gagccaaagt gtcacggcgt ctttttttat ttgtattcct ttcctgtttt 215700
gtactcgtaa actgttgatg ttgtttttac atccaaaagg gcaagtaaga aacaggatga 215760
ggcatggtag gtttgggcgt ggggcggccc tccagcacgg cggcccgggc cgcccggcgg 215820
gtgagcaccc ggcgttgcgc cgtgtctatc ttgtgtttct tctgtgtctt tttcctatct 215880
tgttccgcga cggcctcttt catcacgttc agcatgcgtt cctcgacgcc ctccagggat 215940
cctggggagg agggagtcct agtgaggctt ccaatgttgt tttgtggatt ttcggtttcc 216000
ttttcttggt cgtcatcgtc ggacgtgtcg tcttcctctt gatcctcttc ttcgtccgag 216060
tagtagacgc atagtccttg gttcatcagg ctgggattca tcaggttctg acggggaatc 216120
cgctgttgta gacgtttaac cgcccgttcc aggcgagagc tcatgccgca ccagacgctg 216180
taacgccgca cgggcccgta gcgggctgtt tgttcgcgta catgatcgtt gagctcttgc 216240
caatattgtt tggcacactc cagatcggag gtttgtggat agtcgggtcg gatccgcgga 216300
tcccaactga catcggcggt gccggagact tcgtccagac tgttacgcat agagcaccag 216360
tcgggtcgga cgataaacct gtccttgcgg attaaccatt tataacgtag ttcgtgatgg 216420
cgtgtagagg cccgtacacg ctccacggtc ccaaagcggt cccagaaggg aaagttttcg 216480
tgggggcagc gacccggcac ttccagacgt tcggcgtcgt ccacggcgta gtgaaaacgc 216540
cggccggcct ggtaaatttt gagcagaccc actgttaaca acatatccac gctgtcagcc 216600
aaccgccaga tctcgcggcg agacacgtca aaatagaaaa attcgcaggc tcggtcgacc 216660
aggatcacga aatcggcgtg aaagacgccg gagggtagcg attcgcccac cacacccatt 216720
atcatggttt cacagcataa gcggtccaca aagaacttca acaggtcgtt gaattgctcc 216780
gtctccatac agatgaaggg ccagacgcct ttgaggttct cggcctggcc gcagagcagt 216840
agcggacgtg tcatctcgcc cggagtgcgc agaggcacgc attcgccgcg ataacgacag 216900
gtcacacgct gtagttcgct gatgctgttg tcgtgcaggc gaaggtcgca gataatatga 216960
tccggttgcg tggttagcag cggcgtgcgc atttgctcgc cgtagatggc ctcgcagtgc 217020
aacagcccgt gtcgcgcaaa atcgtccaaa ctgtgcgcca ggtagtaaag caccccgcga 217080
tcgcggtcta gacaccacac ggtttcgtaa cgtcctaaca ggagcaccag acgggcctgg 217140
ctaggtggct caatttcctc tacatacacg aaaaagtcgt catcgtccga gtcctcgtcc 217200
tcagaagagg accgcggccc gtgtactctg ggcaacacgg tggtagagaa ctgcaggacg 217260
cccagagact cgagcgattc ttcgcagcag atgagctgac cccagggcgt ttcgggcccg 217320
tcggtgacag ccgcgctgcc aaagatgtcc tcaaactcta caaaatctag acgccatccg 217380
ggtggcgctg aaatgggaag gctaatgttc atatcagcat agctacgaac taagtggcgg 217440
atgtcctgcc gcaagtcttg gcagagaatg agctttcgta aacccttgag ggtcctccga 217500
acaacggccc cagacgcgta gcgataggac tggcgcatgg tgccgcggcg tggagcggca 217560
cttggcagcc tattttatgg agtttcttca gtgacgtggc ttgttcacgt cgttcgtggg 217620
ctgcggttgg cagctccggt ctgtaaacca cccgaaaaga ctgacatcga cgtcaaagac 217680
tcacgtaatt tggaacatgt gcgaccgcaa agtgcgtcag aatagcacgt ggctttagga 217740
cataaaaagt accgtgaggt ctagacgtgg gttttgtgat tgacacttac accaggtaag 217800
ccaagggacg gtgaaactgt atgtgaggaa tctgggtgct tagacgacta acgtgtaatg 217860
ctttttacag gactgttcga caggtgatag tacctgtaag gtgatgacca cctctacaaa 217920
taatcaaacc ttaacgcagg tgagcaacat gacaaaccac accttaaaca gcaccgaaat 217980
ttatcagttg ttcgagtaca ctcggttggg ggtatggttg atgtgcatcg tgggcacgtt 218040
tctgaacgtg ctggtgatta ccaccatcct gtactaccgt cgtaagaaaa aatctccgag 218100
cgatacctac atctgcaacc tggctgtagc cgatctgttg attgtcgtcg gcctgccgtt 218160
ttttctagaa tatgccaagc atcaccctaa actcagccga gaggtggttt gttcgggact 218220
caacgcttgt ttctacatct gtctttttgc cggcgtttgt tttctcatca acctgtcgat 218280
ggatcgctac tgcgtcatcg tttggggtgt agaattgaac cgcgtgcgaa ataacaagcg 218340
ggccacctgt tgggtggtga ttttttggat actagccgtg ctcatgggga tgccacatta 218400
cctgatgtac agccatacca acaacgagtg tgttggtgaa ttcgctaacg agacgtcggg 218460
ttggttcccc gtgtttttga acaccaaagt taacatttgc ggctacctgg cgcccatcgc 218520
gctgatggcg tacacgtaca accgtatggt gcggtttatc attaactacg ttggtaaatg 218580
gcacatgcag acgctccacg ttcttttggt tgtggttgtg tcttttgcca gcttttggtt 218640
tcctttcaac ctggcgctat ttttagaatc catccgtctt ctggcgggag tgtacaatga 218700
cacacttcaa aacgttatta tcttctgtct atacgtcggt cagtttttgg cctacgttcg 218760
cgcttgtctg aatcctggga tctacatcct agtaggcact caaatgagga aggacatgtg 218820
gacaacccta agggtattcg cctgttgctg cgtgaagcag gagatacctt accaggacat 218880
tgatattgag ctacaaaagg acatacaaag aagggccaaa cacaccaaac gtacccatta 218940
tgacagaaaa aatgcaccta tggagtccgg ggaggaggaa tttctgttgt aattcgatcc 219000
tctctcacgc gtccgccgca catctatttt tgctaattgc acgtttcttc gtggtcacgt 219060
cggctcgaag aggttggtgt gaaaacgtca tctcgccgac gtggtgaacc gctcatatag 219120
accaaaccgg acgctgcctc agtctctcgg tgcgtggacc agacggcgtc catgcaccga 219180
gggcagaact ggtgctatca tgacaccgac gacgacgacc gcggaactca cgacggagtt 219240
tgactacgat gaagacgcga ctccttgtgt tttcaccgac gtgcttaatc agtcaaagcc 219300
agttacgttg tttctgtacg gcgttgtctt tctcttcggt tccatcggca acttcttggt 219360
gatcttcacc atcacctggc gacgtcggat tcaatgctcc ggcgatgttt actttatcaa 219420
cctcgcggcc gccgatttgc ttttcgtttg tacactacct ctgtggatgc aatacctcct 219480
agatcacaac tccctagcca gcgtgccgtg tacgttactc actgcctgtt tctacgtggc 219540
tatgtttgcc agtttgtgtt ttatcacgga gattgcactc gatcgctact acgctattgt 219600
ttacatgaga tatcggcctg taaaacaggc ctgccttttc agtatttttt ggtggatctt 219660
tgccgtgatc atcgccattc cacactttat ggtggtgacc aaaaaagaca atcaatgtat 219720
gaccgactac gactacttag aggtcagtta cccgatcatc ctcaacgtag aactcatgct 219780
tggtgctttc gtgatcccgc tcagtgttat cagctactgc tactaccgca tttccagaat 219840
cgttgcggtg tctcagtcgc gccacaaagg tcgcattgta cgggtactta tagcggtcgt 219900
gcttgtcttt atcatctttt ggctgccgta ccacctaacg ctgtttgtgg acacgttaaa 219960
actcctcaaa tggatctcca gcagctgcga gttcgaaaga tcgctcaaac gtgcgctcat 220020
cttgaccgag tcgctcgcct tttgtcactg ttgtctcaat ccgctgctgt acgtcttcgt 220080
gggcaccaag tttcgcaaga actacactgt ctgctggccg agtttcgcca gcgactcttt 220140
tcccgcgatg tatcctggta ccacagcatg agcttttcgc gtcggagctc gccgagtcga 220200
agagagacat cttccgacac gctgtccgac gaggtgtgtc gcgtctcaca aattataccg 220260
taataaaaaa gcgctacctc ggccttttca tacaaacccc gtgtccgccc ctcttttccc 220320
cgtgcccgat atacacgata ttaaacccac gaccatttcc gtgcgattag cgaaccggaa 220380
aagtttatgg ggaaaaagac gtaggaaagg atcatgtaga aaaacatgcg gtgtttccga 220440
tggtggctct acagtgggtg gtggtggctc acgtttggat gtgctcggac cgtgacggtg 220500
ggtttcgtcg cgcccacggt ccgggcacaa tcaaccgtgg tccgctctga gccggctccg 220560
ccgtcggaaa cccgacgaga caacaatgac acgtcttact tcagcagcac ctctttccat 220620
tcttccgtgt cccctgccac ctcagtggac cgtcaatttc gacggaccac gtacgaccgt 220680
tgggacggtc gacgttggct gcgcacccgc tacgggaacg ccagcgcctg cgtgacgggc 220740
acccaatgga gcaccaactt ttttttctct cagtgtgagc actaccctag tttcgtgaaa 220800
ctcaacgggg tgcagcgctg gacacctgtt cggagaccta tgggcgaggt tgcctactac 220860
gggggttgtt gtatggtggg cgggggtaat cgtgcgtacg tgatactcgt gagcggttac 220920
gggaccgcca gctacggcaa cgctttacgc gtgaattttg ggcgcggcaa ctgcacggcg 220980
ccgaaacgca cctaccctcg gcgcttggaa ctgcacgatg gccgcacaga ccctagccgt 221040
tgcgatccct accaagtgta tttctacggt ctgcagtgtc ctgagcaact ggttatcacc 221100
gcccacggcg gcgtgggtat gcgccgctgt cctaccggct ctcgtcccac cccgtcccgg 221160
ccccaccggc atgacttgga gaacgagcta catggtctgt gtgtggatct tctggtgtgc 221220
gtccttttat tagctctgct gctgttggag ctcgttccca tggaagccgt gcgtcacccg 221280
ctgcttttct ggcgacgcgt ggcgttatcg ccgtccactt ccaaggtgga tcgcgccgtc 221340
aagctgtgtc ttcggcgcat gtttggtctg ccgccgccac cgtcagtcgc accacctggg 221400
gaaaagaagg agctaccggc tcaggcggcc ttgtcgccgc cactgaccac ctggtcacta 221460
ccgccgtttc cgtccacgcg gatacctgac agtccgccgc caccgtacca gcttcgtcac 221520
gccacgtcac tagtgacggt acccacgctg ctgttatata cgtcatccga catcggtgac 221580
acagcttcag aaacaacgtg tgtggcgcac gctacttatg gggaaccccc ggagcccgct 221640
cgatcgacgg ctacggttca ggaatgtacc gttcttaccg ccccgaattg cggcatcgtc 221700
aacaacgacg gcgcggtctc tgaaggccaa gaccatggag atgcggttca ccatagcctg 221760
gatgtggttt cccagtgtgc tgctgatact ggggttgttg acacctccga gtaacgggtg 221820
caccgtcgat gttggacgaa acgtatccat tggagaacag tgccgccttc gaaacggtgc 221880
gacgttctcc aagggagaca tcgaaggtaa cttcagtggg cccgtcgtcg tggagttgga 221940
ctacgaagat atcgatatta ctggcgaacg gcagcgactt cggttccatc tcagcggact 222000
cgggtgtcct acaaaggaaa atataagaaa agacaatgaa agcgacgtca acggtggaat 222060
tcgctgggct ctatatatac aaaccggcga cgccaagtac ggtattcgta accagcattt 222120
gagtatacgg ttaatgtatc ctggggaaaa aaatacacaa cagctgttgg attctgattt 222180
cagttgcgaa cgtcaccgga gaccgtccac gccgttggga aagaacgccg aagtgcctcc 222240
cgcgacccgc acgtcttcta catacagcgt cctcagcgct tttgtagtgt ggatcggatc 222300
cggcctcaat atcatctggt ggaccggcat cgtgcttctg gcggtggacg ctctcggact 222360
tggcgagcgt tggctgaggt tagcactgtc tcaccgggac aaacatcacg catcgcgaac 222420
cgcggcgctc cagtgtcaac gcgacatgtt acttcggcaa cgtcgacggg ctcggcggct 222480
gcacgccgtt tctgaaggca aactgcagga agagaagaaa cgacagtctg ctctggtctg 222540
gaacgttgag gcgcgaccct ttccgtccac acatcagctg attgtgctgc cccctcctgt 222600
agcgtcagct cctcctgcgg ttccctcgca gccccccgag tattcgtctg tgtttccgcc 222660
tgtataaaaa taaagagacg ggaggctgat cgcggccttc agcgtctcat ttgtctttac 222720
tctcgagtgc ggtcggtgtc tcgtcggtga gacgaggccg ccgcccgaca agttcgatct 222780
catgtcgctc ttggagcgcg aagagagttg gcgtcgcgta gtcgactact cgcacaacct 222840
gtggtgtacg tgcggtaact ggcagagcca cgttgagatt caggacgagg agccaaactg 222900
cgagcagccg gagcccgcac actggctgga atacgtggcg gtccagtggc aggcccgggt 222960
tcgcgattct cacgatcgct ggtgtctctg caacgcctgg cgtgatcacg ccttgcgcgg 223020
ccgttggggt acggcgtatt cctcgggttc ctcggcctct tcctccggtt tcgtcgcgga 223080
gagcaagttc acctggtgga aacgactgcg ccacagtacc cggcgctggt tgtttcgccg 223140
ccggcgagct cgatacactc cgtctaactg tggggaaagt agcactagca gcggccagag 223200
tagcggtgac gagagtaact gcagtctacg cacccacggc gtgtacacac ggggtgaaca 223260
acactaatcg ataagtcgcg tgtaggcgac tggctacatc aaccggatat ctgcggggat 223320
ttaaaaagac gacccgttgt catccggctt agaccaaacc gtccttttat catcttccgt 223380
cgccatggct atgtacacat ccgaatccga acgcgactgg cgtcgtgtaa tccacgactc 223440
gcacggcctg tggtgcgact gcggcgactg gcgagagcac ctctattgtg tgtacgacag 223500
ccattttcag cgacgaccca cgacccgagc cgaacggagg gccgccaatt ggcggcgaca 223560
gatgcggcgg ttacaccgtt tgtggtgttt ttgtcaggac tggaagtgtc acgcgttata 223620
cgccgagtgg gacggcaaag aatccgacga cgagtcgtcg gcgtcttcct cgggcgaagc 223680
gccagagcaa caggtccccg cttggaagac cgtgcgggcc ttctcgcggg cctaccacca 223740
ccgcattaac cggggtctgc ggggcacgcc cccaccgcgc aacttgccgg gatacgagca 223800
cgcctccgag ggctggcggt tttgcagtcg acgggaacgg cgagaggacg atcttcgcac 223860
gcgggctgag ccggaccgcg tggtgttcca gttaggggga gtaccccctc gccgtcaccg 223920
ggaaacttac gtgtaagaac acggcgtgac aataaacaac atagcgtaaa tccccgtgtg 223980
atgtgtgtga ttgacgttcg ggaaacatgt ccccatcatc agcgtcacaa ttgacgtggg 224040
ttggtcactg acgtgcagga tgttacgcga gtcagagaat cgcataagaa cggagtggtg 224100
agcgggttcc cacaggagtc tctggcgcaa aagcaccatg agcctcaggt tccccgagag 224160
ggtgggttac gagaaactgg gataccgccc gcatgccaaa cgcgtgcggg tgcatgactc 224220
gttgggattg acgcggttta tcatgaggca actcatgatg tacccgctgg tgttgccgtt 224280
cacttttccg ttttacgtgc cgcggtccta gcacgtcagt ggtgacgctg ataattgcaa 224340
catggcccat gacgaacccg cttgggacga acgtcaatac cacgtcaaac caccgtgact 224400
tggctgaacg ttgaaacata aagccaaagc gccgtcggca cttggcttca gagcagcgcc 224460
tcggggcgat gcgacggcga tgaacttaga gcaactcatc aacgtccttg gtctgctcgt 224520
ctggattgcc gctcgtgctg tcagccgcgt tggtccgcat ggctccggac tcgtttatcg 224580
tgagcttcat gatttctacg ggtatctgca gctggacctt ctgggaccag tggtggcggg 224640
gaatcgctca gtccggacct ggagagagca ggcggaccga gccagaggga ccttcgcttg 224700
gcgttcaggc cttaatacta gccgcatctt acctgtcggc agcatgtatc ggggctccga 224760
cgccttaccc gccggcctgt atcgtcccga agaagaggtg ttcctcctct tgaatcgctg 224820
ccatgggcca ctgtcaacgc cgaaaaatgc ttgtctggct gaggttggtg tcgctaatgc 224880
cacttttttg tctcgcttca atgtcggtga ttttcacgga gcgtcatggg aaaacggtac 224940
cgctcccgat ggagagcccg gggtatgctg aaattcctct taaaatttcg taaacgacgt 225000
cgtccagtcg ttgtgccgcg attcgtacgg ttcatcgtct acgtcgtttt gttcaccgtc 225060
gctgtgcaac gcgtgaaaca agagcgtgat gcgcaccttc ggcggtatga agaacgatta 225120
cggaaaaacc gcgcacggcg tcggcagtct tttccgtgac ttggggcgat gggtccgagc 225180
tgcggtatgg gtcacggcgg cgtgtgtttt attgacgaag atgccgatgt gtgactaaaa 225240
acgtcccagc cccagagcga tatgtttcaa taaaaaaaat atgtagtatc atattatgcg 225300
tgtcctggtt tttcattttt ggatgtatgt atcgcataaa gggtggcgag gtgtgaggat 225360
gaaacatatg cagatacgca gtgttgttat ccgaacgaaa cccgtgtaat gcgtacaacg 225420
gtacttcagt atgaaagtcc cgtgtgtggg gggggggggc aaatagttgc gtttgccgtt 225480
gggcgtacgc tacgtttgta tttctggcta taatatgtgc ggtcatgtgt cgatgttcct 225540
attgggaagg gtgtgactgt agggtgtata aagtacggtg ggacgcagag ggacattgat 225600
agaaacaggt tgagcgctgt acgagtttca cacgctgaat cggcgccaag aataaaacag 225660
tggttattcg taaaagtatg gggggggggg ggatgttgtc gacggttgtt agatgcattg 225720
cgtatctgta ttagtagttt tgcaagccgt ggtgcgtgtt attgtgacgt agcaattatc 225780
gtattgtgca tgtgtcgttc atcacagagt ttagtatact aatatgaagc gtcgcgagta 225840
ttaaagcaat tggtgtctct gtgctagtct aacaacacct gtgtaatgcg tacaacgaga 225900
aaaaagacgc gaaagcaacg tgtatggggg ggggggggaa taatattgct aatcatgcgt 225960
cttgcagtac agatagccgc tgtatcttac gcgtattgtc gcaacagttc cacatcggtg 226020
taattggatg tctggtactt atcactggcg tcgttataac attgtaaaac aagttttcga 226080
aacataacga cagctgcaaa agaaaaccag tttattgagc attgtaatgg tagtgtgtgg 226140
ctatattaga aaacgtgacg cgtcgcatgt cgcggcacaa tctggcagcg gggtcggggt 226200
agggtacggt gggaggcatg tacacagatg gaacaaaagc agaagtaacg tgagaaggag 226260
catacagtcc agtatccagc ggttcctgag tagcaccacc catcaactga atgccctcat 226320
gagtaaaagt ctgcgggcga cagcccttgg ggaccgttgg catgggacga tcaatctcca 226380
aaccacagcg taacaccgtt ttcttccaac gtcgttgata gacgtcgttt ttacggttac 226440
tcccaagaac ccagaaagtc tcgtccaagt cgtaccagga atcttctccg gggagacgcg 226500
acggtttcca atcctcgtcg tctcgtctca aagcacgtcc caaactggct tgaggagtca 226560
acggtggttc tgtgggtcgg gtgtagcgcg agtgttttcc cttcatgagc gattcatcct 226620
ccttgccttt aggctttttg gtctttttgt gtatcatctg gccgccggcc tccataacca 226680
ccgtggccaa gtccagtccc agagcttgag cgtcggcgcg gcgtcgggcg tcttgcaggt 226740
agtcttccac atttgcacag atggccgggt gtttggtggc tagggtgagg acctcagcct 226800
cgccgcgacc cggacgtagc aaaaaagcca actgcccgtg cggctcgcgc gcccacagcg 226860
cggcgcgcgg gtgcaggtgc agcgcgtccc agcgcggccg ctcccactgc tcgcggtcca 226920
gctcgggcag cagccgccgc gcggcctcgg cggcgggcgc cgactcgcgt cccagcgcca 226980
gcgcgcccag cacgcccgcg cgcagaaagt gcgacagctc cgccgccagc gggtacacgt 227040
gcccgtccag cgggcagtac ccgaacacgg cgcccagctc gtccagcagc accaccagca 227100
tggcgcgcgg cacggtcccc gacgccgccg gacccgccat cgctgtcgaa cccaccatca 227160
ccgtcggcgc cgctgctgct gccgcgtccg ccccgaccac cgcgtgcgcg tccgcgttag 227220
gcacgcaaat cgcgcccccg ccggcggcgc cgtacggctg cggaggcaca ggtacagcgg 227280
accccacggc tcccgctatc gcgcacggcg cgtccccgcc ggcggcctcc gtctccgtgc 227340
cgctcgccgc tggcggcgac gtcgtccccg ccgccgtccc cgtcgccggc cccgccgcgc 227400
agcccagcca ccgcgcgggc agcaccgcgc ccagcgccag ccagccgcag cacagacgct 227460
ggttcaggtg ccgacgcacg gccgtcagca gcgacgcggg gtgcggcgcc gacgcgaacg 227520
gctcgtactg cgccagctcc tgccacgcgc ccagcagtac catcggctgc agtcgcctgc 227580
ccggcgtctg cagcgccacc gtcgtgccgg cccaccgccg gcgcagctcc cgtccgagcg 227640
ccgtcgcctc ctcggcgcgc agcaacgtct gtcggagcgc cggctgaggc agcagcgtcg 227700
cgcgcggggt gcccacgccc agccggttgc agcggtacag ccgcaccacc tcgcccgcgc 227760
cgtgccgaaa ccactcgtcc gcgtcgcgcg ccgctaggat cagcgtgttg tttgccaggt 227820
cgtacacgaa cacgcggaac ccggcgccca gcgccaggta cagtccgtcc tgcgcgcaca 227880
gaccctcggg atggccggcc ttgtcgccca acgtcgggtc ggctgcgggg tccacctcgt 227940
gcaccacggt agccaccagt acgatccacg cgtcccgcgg cgacagttga cgcaggtccg 228000
tcgcgcccac gccgttcatc tggctgcgcg gcgtcacccg cgcgtagaat ccgtacggcc 228060
gtccgagcgg cagcagcgtg cccgcgtcgc gctgcgacca cttgcgcatg gcgcggcccg 228120
tgctgttggc caaaaacgcc gcgcgccaca cggcgcccat ggcctggtat tccagctccg 228180
tcagcgcctg gcgctccacc ggaatctgag acagcaacag gcgctccggg ccgtgccaaa 228240
agttgctatt gttgccgcta ctcggagggg cgcccggcgg cccgcggggt tctacccggt 228300
ggacgccgtg gcccggcgtc gtcgtagccg cagcactcgc accagtgccc gctgtggacg 228360
gcgctcccat cggcacacaa gaagaaggag gagaggaacc aacccccgaa ggccctccgg 228420
ccccgcggcc gcgaccaagg ggcggggggc gcggcgacat gccgttgcgc tgggccatgg 228480
gcgccggaca cctccgacgt ccactatata ggaagcaaac ccgcgtcagc gagcacgcgg 228540
tttagacacg cggacgcctt cgtcgcccgt gtgccgcggg cgacacgcag ctggctttta 228600
taggcagcga cgtgcacggc gcgtgctggc gccgccttgg cgccacgcag tctggaaggc 228660
cgtggactgg gaaaggcagc tacccgaagg aagacgcgcg gcaggcgcgt accactggag 228720
cgcacagccg cctcccgggc gcgcacccat ctaggtggac gcccgacatc cattccgggc 228780
cgcgtggtgg gtcctcgagg ggcggggggg tgtttttagc gggggggtga aacttggagt 228840
tgcgtgtgtg gacggcgact agttgcgtgt ggtgcggagg acggcgacgg cgaataaaag 228900
cgacgtgcgg cgcgcacggc gaaaagaaga cgcgtgtctg tgtctgtgtg attccccggg 228960
gaaaagagga agttcccggg ggacggcagc atgggtccct ggggacacac gaaaagcaac 229020
gcccgggggc gagggacgac ggccctgggg accgcggggg aaataacggc cgcgaggcca 229080
cacactcgtt cctgcgaagc cgcacacccc gaggccgcgc acaccgccga cacaccccgc 229140
caccacaccc cgccggcaca cccgccacac gcccgcgaca cacccggcac gacacacccg 229200
gcacacgccc gcgacacacc ctgacacacc ctgccaacac acccccgaca cacccaacac 229260
acgcccgcga cacacccggc acacacccac ccggccgcgc cccgacacac ccaaaacacc 229320
gccggtgcgg ggccgcgtgg tgggtcctcg aggg 229354

Number	Name	Date	Kind
3959466	Plotkin	May 1976	A
5552143	Plotkin et al.	Sep 1996	A
5591439	Plotkin et al.	Jan 1997	A
5721354	Spaete et al.	Feb 1998	A
5925751	Spaete et al.	Jul 1999	A
6040170	Spaete et al.	Mar 2000	A
6277621	Horsburgh et al.	Aug 2001	B1
6291236	Spaete et al.	Sep 2001	B1

Number	Date	Country
WO 9503400	Feb 1995	WO
WO 9943842	Feb 1999	WO
WO 9906582	Nov 1999	WO

Generation of human cytomegalovirus yeast artificial chromosome recombinants

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