GENETIC ANALYSIS OF MITOCHONDRIAL ASSEMBLY

Information

• Research Project
• 3293537

• ApplicationId

  3293537

• Core Project Number

  R01GM037803

• Full Project Number

  1R01GM037803-01

• Serial Number

  37803

• FOA Number

• Sub Project Id

• Project Start Date

  1/1/1987 - 38 years ago

• Project End Date

  12/31/1989 - 35 years ago

• Program Officer Name

• Budget Start Date

  1/1/1987 - 38 years ago

• Budget End Date

  12/31/1987 - 37 years ago

• Fiscal Year

  1987

• Support Year

  1

• Suffix

• Award Notice Date

  -

Organizations

• University of Basel

The overall aim of this project is to identify the mechanism of mitochondrial assembly. Mitochondria are the main sources of ATP in eukaryotic cells, but they are also essential for many other biochemical processes. The specific aim of this project to isolate and characterize yeast mutants in which mitochondrial assembly is defective. Two such mutants (mas 1 and mas 2) have already been isolated using a "brute force" screen. Additional mutants will be sought by a variety of selection procedures. The genes affected in such mutants will be isolated by genetic complementation with genomic DNA banks from wild-type yeast. Availability of the genes should give information on the properties and the function of the proteins which participate in mitochondrial assembly.

IC Name

• Activity

  R01

• Administering IC

  GM

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  863

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  CBY

• Study Section Name

  Cellular Biology and Physiology Subcommittee 1

• Organization Name

  UNIVERSITY OF BASEL

• Organization Department

• Organization DUNS

  484650064

• Organization City

  BASEL

• Organization State

• Organization Country

  SWITZERLAND

• Organization Zip Code

  CH - 4051

• Organization District

  SWITZERLAND