Claims
- 1. An antibody which specifically binds a glutamate receptor protein subunit selected from the group consisting of GluR1, GluR2, GluR3, GluR4, GluR5, GluR6, and GluR7.
- 2. An antibody according to claim 1, wherein said subunit has the amino acid sequence set forth in SEQ ID NO:2, SEQ ID NO:4, SEQ ID NO:6, SEQ ID NO:8, SEQ ID NO:10, SEQ ID NO:12, or SEQ ID NO:14.
- 3. An antibody according to claim 2, wherein said antibody is a monoclonal antibody and said subunit has the same amino acid sequence as GluR1 set forth as SEQ ID NO:2.
- 4. An antibody according to claim 2, wherein said antibody is a monoclonal antibody and said subunit has the same amino acid sequence as GluR2 set forth as SEQ ID NO:4.
- 5. An antibody according to claim 2, wherein said antibody is a monoclonal antibody and said subunit has the same amino acid sequence as GluR3 set forth as SEQ ID NO:6.
- 6. An antibody according to claim 2, wherein said antibody is a monoclonal antibody and said subunit has the same amino acid sequence as GluR4 set forth as SEQ ID NO:8.
- 7. An antibody according to claim 2, wherein said antibody is a monoclonal antibody and said subunit has the same amino acid sequence as GluR5 set forth as SEQ ID NO:10.
- 8. An antibody according to claim 2, wherein said antibody is a monoclonal antibody and said subunit has the same amino acid sequence as GluR6 set forth as SEQ ID NO:12.
- 9. An antibody according to claim 2, wherein said antibody is a monoclonal antibody and said subunit has the same amino acid sequence as GluR7 set forth as SEQ ID NO:14.
- 10. An antibody which specifically binds a glutamate receptor protein subunit on a cell membrane, wherein said subunit is selected from the group consisting of GluR1, GluR2, GluR3, GluR4, GluR5, GluR6, and GluR7.
- 11. An antibody according to claim 1, wherein said antibody is a monoclonal antibody.
- 12. An antibody which specifically binds to a glutamate receptor protein encoded by at least one gene sequence selected from the gene sequences deposited as ATCC No. 68134, ATCC No. 68132, ATCC No. 68133, ATCC No. 68375, or ATCC No. 68374.
Parent Case Info
This application is a continuation of U.S. Ser. No. 08/013,767, filed Feb. 4, 1993, now abandoned, which is, in turn, a division of U.S. Ser. No. 07/718,575, filed Jun. 21, 1991, now U.S. Pat. No. 5,202,257, which claims priority from PCT/US90/06153, filed Oct. 25, 1990, which is, in turn, a continuation-in-part of U.S. Ser. No. 07/428,116, filed Oct. 27, 1989, now abandoned, the entire contents of each of which are hereby incorporated by reference herein.
ACKNOWLEDGEMENT
This invention was made with Government support under Grant Numbers NS 11549 and NS 28709.01, awarded by the National Institutes of Health. The Government has certain rights in this invention.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4857637 |
Hammonds et al. |
Aug 1989 |
|
Non-Patent Literature Citations (4)
Entry |
Osband et al., Immund Today, 1990, 11:193. |
Harris et al., TiBTech, 1993, 11:43. |
Hampson et al., J Biol Chem., 264:13329, 1989. |
Hampson et al., J Biol Chem, 263:2500, 1988. |
Divisions (1)
|
Number |
Date |
Country |
Parent |
718575 |
Jun 1991 |
|
Continuations (1)
|
Number |
Date |
Country |
Parent |
13767 |
Feb 1993 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
428116 |
Oct 1989 |
|