Claims
- 1. A composition useful for treating a domesticated warm blooded animal to promote growth, improve feed efficiency, or improve leanness, which comprises both of (1) a first compound having the formula ##STR4## wherein: R.sup.1 is hydrogen, hydroxy, or methoxy;
- R.sup.2 is hydrogen or fluoro;
- R.sup.3 is hydrogen or C.sub.1 -C.sub.2 alkyl;
- R.sup.4 is hydrogen or methyl;
- R.sup.5 is hydrogen, fluoro, nitro, hydroxy, SO.sub.2 CH.sub.3 or CONH.sub.2 ; provided that R.sup.1 is hydrogen only when R.sup.5 is nitro or SO.sub.2 CH.sub.3, or an acid addition salt thereof; and (2) a second compound which is a tetracycline, tylosin, penicillin, cephalosporin, polyether, glycopeptide, or orthosomycin, in a ratio of about 1 to about 2 parts by weight of the first compound and about 1 to about 10 parts by weight of the second compound.
- 2. The composition of claim 1 wherein the first compound is 1-(4-hydroxyphenyl)-2-(1-methyl-3-(4-hydroxyphenyl)propylamino)ethanol or an acid addition salt thereof.
- 3. The composition of claim 2 where the second compound is tylosin.
- 4. The composition of claim 2 wherein the second compound is a polyether.
- 5. A method for treating a domesticated warm blooded animal to promote growth, improve feed efficiency, or improve leanness, which comprises administering to the animal both of (1) a first compound having the formula ##STR5## wherein: R.sup.1 is hydrogen, hydroxy, or methoxy;
- R.sup.2 is hydrogen or fluoro;
- R.sup.3 is hydrogen or C.sub.1 -C.sub.2 alkyl;
- R.sup.4 is hydrogen or methyl;
- R.sup.5 is hydrogen, fluoro, nitro, hydroxy, SO.sub.2 CH.sub.3 or CONH.sub.2 ; provided that R.sup.1 is hydrogen only when R.sup.5 is nitro or SO.sub.2 CH.sub.3, or an acid addition salt thereof; and (2) a second compound which is a tetracycline, tylosin, penicillin, cephalosporin, polyether, glycopeptide, or orthosomycin, in amounts which in combination are effective.
- 6. The method of claim 5 wherein the first compound is 1-(4-hydroxyphenyl)-2-(1-methyl-3-(4-hydroxyphenyl)-propylamino)ethanol or an acid addition salt thereof.
- 7. The method of claim 6 wherein the second compound is tylosin.
- 8. The method of claim 6 wherein the second compound is a polyether.
Parent Case Info
This application is a divisional of Ser. No. 08/037,789 filed Mar. 18, 1993 which is a continuation of application Ser. No. 07/606,670 filed Oct. 31, 1990, which is now abandoned; which is a divisional of application Ser. No. 07/328,996 filed Mar. 27, 1989, now U.S. Pat. No. 4,992,473, and issued application Ser. No. 07/153,640 filed Feb. 8, 1988 and issued Jul. 18, 1989, as U.S. Pat. No. 4,849,453; this is a divisional of application Ser. No. 06/860,719 filed May 7, 1986 and issued Mar. 29, 1988 as U.S. Pat. No. 4,734,437; this is a continuation of application Ser. No. 06/628,002 filed Jul. 5, 1984 which is now abandoned; which is a continuation of application Ser. No. 06/462,587 filed Jan. 31, 1983 which is now abandoned.
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Number |
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Date |
Kind |
3818101 |
Baile et al. |
Jun 1974 |
|
4391826 |
Mills et al. |
Jul 1983 |
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Related Publications (1)
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Number |
Date |
Country |
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153640 |
Feb 1988 |
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Divisions (3)
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Number |
Date |
Country |
Parent |
37789 |
Mar 1993 |
|
Parent |
328996 |
Mar 1989 |
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Parent |
860719 |
May 1986 |
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Continuations (3)
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Number |
Date |
Country |
Parent |
606670 |
Oct 1990 |
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Parent |
628002 |
Jul 1984 |
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Parent |
462587 |
Jan 1983 |
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