The present invention relates to a mixing apparatus such as a centrifuge or shaker. In particular, the invention relates to a head that can be coupled to a mixing apparatus and configured to receive either a microplate or test tubes.
In one embodiment, the invention provides a head that can be coupled with a mixing apparatus. The head includes a body that defines a longitudinal axis and includes a plurality of sides that are deformable and are spaced to permit frictional engagement of a microplate between them. The head also includes at least one vertical channel that is configured to removably secure a test tube to the body so that a longitudinal axis of the test tube orients in a direction perpendicular to the longitudinal axis of the body, and at least one horizontal channel that is configured to removably secure a test tube to the body so that a longitudinal axis of the test tube orients in a direction parallel to an axis of the horizontal channel.
In another embodiment, the invention provides a head that can be coupled with a mixing apparatus. The head includes a body that defines a longitudinal axis and a first side, a second side, a third side, and a fourth side that each includes a projection. The body includes a central member for supporting a microplate between the sides. The head includes a first vertical channel, a second vertical channel, a third vertical channel, and a fourth vertical channel. The first vertical channel is configured to removably secure a first test tube to the body in a direction so that a longitudinal axis of the test tube is perpendicular to the longitudinal axis of the body. The second vertical channel is configured to removably secure a second test tube to the body in a direction so that a longitudinal axis of the test tube is perpendicular to the longitudinal axis of the body. The first horizontal channel is configured to removably secure a third test tube to the body in a direction so that a longitudinal axis of the test tube is parallel to the longitudinal axis of the body. The second horizontal channel configured to removably secure a fourth test tube to the body in a direction so that a longitudinal axis of the test tube is perpendicular to the longitudinal axis of the body. The first test tube, the second test tube, the third test tube, and the fourth test tube can be coupled to the body at the same time.
Other aspects of the invention will become apparent by consideration of the detailed description and accompanying drawings.
Before any embodiments of the invention are explained in detail, it is to be understood that the invention is not limited in its application to the details of construction and the arrangement of components set forth in the following description or illustrated in the following drawings. The invention is capable of other embodiments and of being practiced or of being carried out in various ways.
Further with respect to
As illustrated in
A bottom 120 of each of the first and the second sides 54, 58 includes a plurality of test tube apertures 130 that are configured to hold test tubes so that their longitudinal axes orient in a direction parallel to an axis B (
The central member 100 includes a top surface 200 having a non-uniform contour. In other words, the top surface 200 has raised regions 204, 208, 212 and depressed regions 216, 220. The central member 100 also includes a deformable pad 224 that is flush with one of the raised portions 208 of the top surface 200. The pad 224 is constructed from an elastomeric material such as polyurethane foam.
The central member 100 includes a plurality of test tube apertures 250, 254 that are also configured to hold test tubes so that their longitudinal axes orient in a direction parallel to the axis B and therefore, perpendicular to the longitudinal axis A. As illustrated
The apertures 250 of the first row 258 each include an adjacent, concentric wall 270 that projects from the body 50 in a direction parallel to the longitudinal the axis B. The apertures 250 and the walls 270 each define a vertical channel 274 (
The apertures 254 of the second row 262 each include an adjacent, concentric wall 300 that projects from the body 50 in a direction parallel to the longitudinal the axis B. The walls 300 of the apertures 254 in the second row 262 each include a first wall section 304 that is disposed above the top surface 200 of the central member 100 (
The body 50 is also configured to removably receive and frictionally engage a microplate 350. In particular, the first, the second, the third, and the fourth sides 54, 58, 62, 66 are elastically deformable and receive the microplate therebetween. The projections 104 on each of the first, the second, the third and the fourth sides 54, 58, 62, 66 engage and maintain the position of the microplate 350 relative to the body 50 and secure the microplate 350 with a snap-fit engagement. An auxiliary coupling mechanism (not shown) may additionally be used to secure the microplate 350 relative to the body 50. The auxiliary mechanism may be an elastic retention bands (not shown) that are pre-attached to the mixing head, for example.
To assemble the head and housing, the head 10 is secured (i.e., by a snap fit engagement or fastening system) to the housing 18 of the mixing apparatus 14. The rotor post sub-assembly 20 underlies the pad 224 and connects to a switch (not shown) in the housing for activating the motor 22. Once assembled, either the microplate 350 or one or more test tubes may be secured to the head 10. For example, the user can couple the microplate 350 to the head 10 between the first, the second, the third, and the fourth sides 54, 58, 62, 66 using one or more of the projections 104 on those sides. Alternatively, the user may slide one or more test tubes into one or more of the horizontal channels 80, 84, 88, 92 and one or more of the vertical channels 138, 274, 324. The head 10 is configured to receive several sizes of test tubes at the same time. In other words, the head 10 can receive, for example, a 50 ml test tube in one of the horizontal channels 80, 84 and a 15 ml test tube in another of the horizontal channels 88, 92 at the same time. Also, the head 10 can receive, for example, a 1 ml test tube in one of the vertical channels 138, a 1.5 ml test tube in another of the vertical channels 274, and a 2 ml test tube in yet a third of the vertical channels 324, all at the same time. Similarly, the head 10 can receive a test tube in one or more of the horizontal channels 80, 84, 88, 92 and a test tube in one or more of the vertical channels 138, 274, 324 at the same time. Once appropriately positioned, the motor 22 is actuated by the switch 26. Actuation of the motor 22 moves (e.g., translates, oscillates, or translates and oscillates) the head 10 relative to housing 18 to agitate the contents of the microplate 350 or of the one or more test tubes.
The head 10 is depressible relative to the housing 18 to manually actuate the motor 22, if switch 26 is in the intermittent position. In particular, when a manual force is applied to the pad 224, the pad 224 will move toward the sub-assembly 20 in the housing 18, thereby actuating the motor 22. Removal of the force causes the motor 22 to stop. Therefore, a user can, for example, press a bottom, closed end of a test tube into the pad 224 and actuate the motor 22. By holding the test tube against pad 224 while the motor is actuated, the contents of the test tube are agitated. Removing the test tube from the pad 224 shuts the motor off. If the switch 26 is at the “intermittent” position and the speed dial 28 is set to maximum, a vortex motion will be created within the contents of the test tubes held in or pressed against the head.
Various features and advantages of the invention are set forth in the following claims.
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