Hearing aid optical monitoring apparatus

Abstract
A hearing aid includes a speaker driver, an optical source secured directly to the speaker driver, an optical detector secured directly to the speaker driver, a first light guide extending outwardly from the optical source and in optical communication with the optical source, and a second light guide extending outwardly from the optical detector and in optical communication with the optical detector. The first light guide is configured to deliver light from the optical source into an ear region of the subject via a distal end thereof, and the second light guide is configured to collect light from the ear region via a distal end thereof and deliver collected light to the optical detector. The hearing aid may include at least one signal processor configured to process signals produced by the optical detector, and at least one of the following: an accelerometer, a humidity sensor, an altimeter, a temperature sensor.
Description
FIELD OF THE INVENTION

The present invention relates generally to monitoring devices and, more particularly, to optical monitoring devices.


BACKGROUND OF THE INVENTION

There is growing market demand for personal health and environmental monitors, for example, for gauging overall health and metabolism during exercise, athletic training, dieting, daily life activities, sickness, and physical therapy. However, traditional health monitors and environmental monitors may be bulky, rigid, and uncomfortable—generally not suitable for use during daily physical activity.


Sensors for detecting biometric signals, such as vital signs and other physiological information, are configured to isolate the biometric signals from other spurious signals and deliver biometric readings, such as heart rate, respiration rate, blood pressure, etc., to the user. Unfortunately, spurious signals that may be difficult to isolate from a biometric signal are associated with physical movement (e.g., physical exercise, such as walking, running, daily activities, etc.) of a sensor relative to the user or the environment of the user (e.g., sunlight, room light, humidity, ambient acoustical or electromagnetic noise, temperature extremes or changes in temperature, etc.).


For example, referring to FIG. 1, a conventional photoplethysmography (PPG) optical sensor 10 is illustrated that includes an optical source 14, and an optical detector 16. The optical sensor 10 is desirably positioned directly against the body B (i.e., the skin) of a subject wearing the optical sensor such that light L1 from the optical source 14 is directed into the body B and is subsequently detected by the optical detector 16. However, movement of the user can cause the sensor 10 to move relative to the body B such that light L2 can take a direct path from the optical source 14 into the optical detector 16 (for example by reflection off of the body, i.e., the skin, of the user), which increases spurious signals. Moreover, motion artifacts may cause the distance between the sensor 10 and body B to change in time, thereby modulating L1 and L2 in time, leading to motion artifact noise on the signal generated by the detector 16.


Previous ways of isolating heart rate signals from other signals include the use of passive and active signal processing algorithms, increasing optical sensor output and displacing the optical source from the photodetector, and pushing the sensor more firmly against the user so as to limit the effects of physical movement on the heart rate signal.


SUMMARY

It should be appreciated that this Summary is provided to introduce a selection of concepts in a simplified form, the concepts being further described below in the Detailed Description. This Summary is not intended to identify key features or essential features of this disclosure, nor is it intended to limit the scope of the invention.


According to some embodiments of the present invention, a wearable optical sensor includes at least one optical emitter, at least one optical detector and light-guiding optics. The light-guiding optics are configured to direct a beam pattern of light upon a body of a subject wearing the optical sensor and to detect light scattered from a detection region of the body. In addition, the light-guiding optics are configured to prevent overlap between the beam pattern of light and the detection region when the wearable sensor is separated from the body, for example, by a distance up to about three tenths of a centimeter (0.3 cm). In some embodiments, the light-guiding optics includes optical filtering material and/or light polarizing material.


According to some embodiments of the present invention, an optical sensor module for detecting and/or measuring physiological information from a subject and that can be integrated into a wearable device, such as a headset (e.g., an earbud, etc.), an armband, a wristband, clothing, foot apparel, a ring, etc., includes a base and a housing secured to the base. The base includes an optical source and an optical detector. The housing overlies the optical source and optical detector and includes a first light guide comprising light transmissive material in optical communication with the optical source and a second light guide comprising light transmissive material in optical communication with the optical detector. The first and second light guides define respective first and second axial directions that are outwardly diverging. The first axial direction of the first light guide is angled relative to a plane defined by a surface of the optical source, and the second axial direction of the second light guide is angled relative to a plane defined by a surface of the optical detector. When the sensor module is in use and placed adjacent the skin of a user, a substantial majority of light rays emanating from the optical source and directed into the skin of the user cannot overlap with light rays returning through the skin of the user and collected by the second light guide when the housing is separated from the skin, for example, by a distance up to about three tenths of a centimeter (0.3 cm).


In some embodiments, at least one of the first and second light guides is cylindrical. In other embodiments, at least one of the first and second light guides is non-cylindrical.


The first and second light guides include opposite proximal and distal ends. In some embodiments, the proximal and distal ends of at least one of the first and second light guides have different sizes. For example, the diameter of a light guide distal end may be greater than a diameter of the proximal end thereof. Alternatively, the diameter of a light guide distal end may be smaller than a diameter of the proximal end thereof. In some embodiments, the proximal and distal ends of at least one of the first and second light guides may have different configurations. For example, the proximal end of a light guide may have one type of geometric configuration and the distal end may have a different geometric configuration. As an example, the proximal end may have a triangular configuration and the distal end may have a rectangular configuration, etc.


In some embodiments, the distal end of at least one of the first and second light guides has a curved surface. In other embodiments, the distal end of at least one of the first and second light guides has a textured surface.


In some embodiments, multiple light guides may be substituted for a single light guide either on the optical source or over the optical detector.


In some embodiments, single or multiple light guides may be placed over multiple optical sources or multiple optical detectors.


Optical sensor modules according to embodiments of the present invention are advantageous because they can lower the sensitivity of an optical signal to sensor-user movement related noise, thereby enabling a significant improvement in heart rate monitoring consistency across subjects and types of exercise activities.


According to some embodiments of the present invention, a headset includes a base comprising an optical source and an optical detector, and a housing that is secured to the base and is configured to be positioned at or within an ear of a subject. The housing overlies the optical source and optical detector and includes a first light guide in optical communication with the optical source and a second light guide in optical communication with the optical detector. The first and second light guides define respective first and second axial directions that are outwardly diverging.


According to some embodiments of the present invention, an optical sensor module includes a base having an optical source and an optical detector, a housing secured to the base that overlies the optical source and optical detector, and at least one light polarizing element in optical communication with the optical source and the optical detector. The at least one polarizing element is configured to polarize light emitted by the optical source and/or polarize light detected by the optical detector.


In some embodiments, the at least one light polarizing element is a light polarizing film, a light polarizing lens, and/or a light polarizing light guiding material in the optical path of the optical source and/or the optical detector.


In some embodiments, the at least one light polarizing element includes a first light polarizing element in optical communication with the optical source and a second light polarizing element in optical communication with the optical detector. The first and second light polarizing elements may have the same light polarization orientation or may have respective different light polarization orientations.


In some embodiments, the sensor module housing includes at least one window through which light from the optical source passes and/or through which light detected by the optical detector passes. The at least one window includes the at least one polarizing element. For example, the at least one window may include a first window in optical communication with the optical source and a second window in optical communication with the optical detector. The first window includes a polarizing element (e.g., a polarizing film, etc.) and the second window includes a polarizing element (e.g., a polarizing film, etc.). The first and second window polarizing elements may have the same light polarization orientation or may have respective different light polarization orientations.


According to other embodiments of the present invention, an optical sensor module for detecting and/or measuring physiological information from a subject includes a base having an optical source and an optical detector, and a housing secured to the base that overlies the optical source and optical detector. The housing includes a first light guide in optical communication with the optical source and a second light guide in optical communication with the optical detector. The first light guide includes light polarizing material that is configured to polarize light emitted by the optical source, and the second light guide includes light polarizing material that is configured to polarize light detected by the optical source. The first light guide light polarizing material and the second light guide light polarizing material may have the same light polarization orientation or may have respective different light polarization orientations.


According to other embodiments of the present invention, an optical sensor module for detecting and/or measuring physiological information from a subject includes a housing, an optical source supported by the housing, an optical detector supported by the housing, and at least one light polarizing element supported by the housing. The at least one light polarizing element is configured to polarize light emitted by the optical source and/or polarize light detected by the optical detector. In some embodiments, the at least one light polarizing element is a light polarizing film, a light polarizing lens, and/or a light polarizing light guiding material in the optical path of the optical source and/or the optical detector.


In some embodiments, the at least one light polarizing element includes a first light polarizing element in optical communication with the optical source and a second light polarizing element in optical communication with the optical detector. The first and second light polarizing elements may have the same light polarization orientation or may have respective different light polarization orientations.


In some embodiments, the sensor module housing includes at least one window through which light from the optical source passes and/or through which light detected by the optical detector passes. The at least one window includes the at least one polarizing element. For example, the at least one window may include a first window in optical communication with the optical source and a second window in optical communication with the optical detector. The first window includes a polarizing element (e.g., a polarizing film, etc.) and the second window includes a polarizing element (e.g., a polarizing film, etc.). The first and second window polarizing elements may have the same light polarization orientation or may have respective different light polarization orientations.


According to other embodiments of the present invention, an earbud includes a speaker driver, and a sensor module secured to the speaker driver that is configured to detect and/or measure physiological information from a subject wearing the earbud. In some embodiments, the sensor module includes a printed circuit board (PCB), an optical source secured to the PCB, and an optical detector secured to the PCB. In some embodiments, the PCB is an elongated, flexible PCB having a distal end portion, and the optical source and optical detector are secured to the PCB at the distal end portion.


In some embodiments, the earbud includes a first light guide coupled to the optical source and a second light guide coupled to the optical detector. The first light guide is configured to deliver light from the optical source into an ear region of the subject via a distal end thereof, and the second light guide is configured to collect light from the ear region via a distal end thereof and deliver collected light to the optical detector.


In some embodiments, the earbud includes one or more additional sensors secured to the speaker driver. Exemplary additional sensors include, but are not limited to, accelerometers, humidity sensors, altimeters, and temperature sensors.


In some embodiments, the earbud includes at least one signal processor configured to process signals produced by the optical detector. In other embodiments, the earbud is in communication with a data processing unit that is configured to process signals produced by the optical detector.


According to other embodiments of the present invention, a monitoring device includes a band capable of at least partially encircling a portion of a body of a subject, and an optical source and an optical detector supported by the band. The band includes a first light guide in optical communication with the optical source and a second light guide in optical communication with the optical detector. The first and second light guides define respective first and second axial directions, and the first and second axial directions diverge outwardly from the band. In some embodiments, the first and second light guides are angled relative to each other such that light rays emanating from the optical source and directed into the skin of the subject via the first light guide cannot overlap with light rays collected by the second light guide even when the housing is separated from the ear by a distance up to about three tenths of a centimeter (0.3 cm). In some embodiments, the first axial direction of the first light guide is angled relative to a plane defined by the optical source, and the second axial direction of the second light guide is angled relative to a plane defined by the optical detector.


It is noted that aspects of the invention described with respect to one embodiment may be incorporated in a different embodiment although not specifically described relative thereto. That is, all embodiments and/or features of any embodiment can be combined in any way and/or combination. Applicant reserves the right to change any originally filed claim or file any new claim accordingly, including the right to be able to amend any originally filed claim to depend from and/or incorporate any feature of any other claim although not originally claimed in that manner. These and other objects and/or aspects of the present invention are explained in detail below.





BRIEF DESCRIPTION OF THE DRAWINGS

The accompanying drawings, which form a part of the specification, illustrate various embodiments of the present invention. The drawings and description together serve to fully explain embodiments of the present invention.



FIG. 1 is a side section view of a conventional optical sensor illustrating how light can take a direct path from an optical source to an optical detector via reflection off of the skin of a subject wearing a device incorporating the optical sensor.



FIG. 2 is a side section view of an optical sensor module having light guides, according to some embodiments of the present invention.



FIG. 3A is an enlarged, partial view of the distal end of a light guide from the optical sensor module of FIG. 2 and which illustrates a curved configuration of the surface of the light guide distal end.



FIG. 3B is an enlarged, partial view of the distal end of a light guide from the optical sensor module of FIG. 2 and which illustrates a textured configuration of the surface of the light guide distal end and light rays emanating from the textured surface.



FIG. 4 is a side section view of an optical sensor module having multiple light guides, according to some embodiments of the present invention.



FIG. 5 is a graph illustrating the effect on an optical signal from a sensor module as a function of distance of the sensor module from the body of a subject wearing the sensor module.



FIG. 6 is a side section view of an optical sensor module having light guides, according to some embodiments of the present invention, and illustrating a light detector being moved in an arc above the optical source and a light source being moved in an arc above the optical detector.



FIG. 7 is a graph illustrating the results of a sweep test as illustrated in FIG. 6 for a sensor module without light guides, for a sensor module with light guides with flush, un-textured end surfaces, and for a sensor module with textured end surfaces.



FIG. 8 is a cross sectional view of a ring incorporating an optical sensor module according to some embodiments of the present invention.



FIG. 9A illustrates an optical sensor module integrated within a mobile device and that is configured to engage an optical module worn by a user, according to some embodiments of the present invention.



FIG. 9B is a side section view of the optical sensor and optical module of FIG. 9A prior to the optical sensor engaging the optical module.



FIGS. 10A-10B are side section views of an optical sensor module and an optical module, according to other embodiments of the present invention.



FIG. 11A is a side section view of an optical sensor module, an optical module, and an optical coupler therebetween, according to some embodiments of the present invention.



FIG. 11B is a side section view of an optical sensor module, an optical module, and an optical coupler therebetween, according to some embodiments of the present invention.



FIG. 12A is a front perspective view of an optical sensor module, according to some embodiments of the present invention.



FIG. 12B is a side view of the optical sensor module of FIG. 12A illustrating the light guides therein angled away from each other.



FIG. 12C is a side view of the optical sensor module of FIG. 12A.



FIG. 12D is a front view of the optical sensor module of FIG. 12A.



FIG. 12E is an end view of the optical sensor module of FIG. 12A.



FIG. 12F is a rear perspective view of the optical sensor module of FIG. 12A.



FIG. 13A is a front view of an earbud speaker driver with integrated optomechanics, according to some embodiments of the present invention.



FIG. 13B is a rear view of the earbud speaker driver of FIG. 13A.



FIG. 13C is a side view of the earbud speaker driver of FIG. 13A.



FIG. 13D is a rear view of the earbud speaker driver of FIG. 13A with the light guides coupled to a sensor module, according to some embodiments of the present invention.



FIG. 14 is an illustration of a human ear with various portions thereof labeled.



FIGS. 15-20 illustrate an earbud speaker driver positioned relative to an ear of a subject, according to various embodiments of the present invention.



FIGS. 21A-21B and 22A-22B illustrate a speaker driver sensor, according to some embodiments of the present invention.



FIGS. 23-25 are block diagrams illustrating various configurations of a data processing unit in communication with an earbud having a sensor module, according to embodiments of the present invention.



FIG. 26 is a block diagram an earbud having a sensor module and data processing capability, according to some embodiments of the present invention.



FIG. 27 illustrates a pair of earbuds which each contain a sensor module according to embodiments of the present invention, and which are in communication with a data processing unit.



FIG. 28 illustrates an earbud unit containing a sensor module and a data processing unit, according to some embodiments of the present invention.



FIGS. 29-31 illustrate a speaker driver sensor positioned within an ear of a subject, according to some embodiments of the present invention.



FIG. 32A is a side view of a biometric monitoring device, according to some embodiments of the present invention, and illustrating the center of gravity of the monitoring device.



FIG. 32B is a front view of the biometric monitoring device of FIG. 32A.



FIG. 32C is a front perspective view of the biometric monitoring device of FIG. 32A.



FIG. 32D is a front view of the biometric monitoring device of FIG. 32A illustrating the intersection of orthogonal planes along which the center of gravity of the monitoring device is located.



FIG. 32E is a side view of the biometric monitoring device of FIG. 32D.



FIG. 32F is a front perspective view of the biometric monitoring device of FIG. 32D.



FIG. 33 is a top perspective view side section view of an optical sensor module that includes at least one light polarizing element, according to some embodiments of the present invention.



FIG. 34 is a side section view of the optical sensor module of FIG. 33.



FIG. 35 is a side section view of an optical sensor module that includes at least one light polarizing element, according to some embodiments of the present invention.





DETAILED DESCRIPTION

The present invention will now be described more fully hereinafter with reference to the accompanying figures, in which embodiments of the invention are shown. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Like numbers refer to like elements throughout. In the figures, certain layers, components or features may be exaggerated for clarity, and broken lines illustrate optional features or operations unless specified otherwise. In addition, the sequence of operations (or steps) is not limited to the order presented in the figures and/or claims unless specifically indicated otherwise. Features described with respect to one figure or embodiment can be associated with another embodiment or figure although not specifically described or shown as such.


It will be understood that when a feature or element is referred to as being “on” another feature or element, it can be directly on the other feature or element or intervening features and/or elements may also be present. In contrast, when a feature or element is referred to as being “directly on” another feature or element, there are no intervening features or elements present. It will also be understood that, when a feature or element is referred to as being “connected”, “attached”, “coupled”, or “secured” to another feature or element, it can be directly connected, attached, coupled, or secured to the other feature or element or intervening features or elements may be present. In contrast, when a feature or element is referred to as being “directly connected”, “directly attached”, “directly coupled”, or “directly secured” to another feature or element, there are no intervening features or elements present. Although described or shown with respect to one embodiment, the features and elements so described or shown can apply to other embodiments.


The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the singular forms “a”, “an” and “the” are intended to include the plural forms as well, unless the context clearly indicates otherwise.


As used herein, the terms “comprise”, “comprising”, “comprises”, “include”, “including”, “includes”, “have”, “has”, “having”, or variants thereof are open-ended, and include one or more stated features, integers, elements, steps, components or functions but does not preclude the presence or addition of one or more other features, integers, elements, steps, components, functions or groups thereof. Furthermore, as used herein, the common abbreviation “e.g.”, which derives from the Latin phrase “exempli gratia,” may be used to introduce or specify a general example or examples of a previously mentioned item, and is not intended to be limiting of such item. The common abbreviation “i.e.”, which derives from the Latin phrase “id est,” may be used to specify a particular item from a more general recitation.


As used herein, the term “and/or” includes any and all combinations of one or more of the associated listed items and may be abbreviated as “/”.


As used herein, phrases such as “between X and Y” and “between about X and Y” should be interpreted to include X and Y. As used herein, phrases such as “between about X and Y” mean “between about X and about Y.” As used herein, phrases such as “from about X to Y” mean “from about X to about Y.”


Spatially relative terms, such as “under”, “below”, “lower”, “over”, “upper” and the like, may be used herein for ease of description to describe one element or feature's relationship to another element(s) or feature(s) as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is inverted, elements described as “under” or “beneath” other elements or features would then be oriented “over” the other elements or features. Thus, the exemplary term “under” can encompass both an orientation of over and under. The device may be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly. Similarly, the terms “upwardly”, “downwardly”, “vertical”, “horizontal” and the like are used herein for the purpose of explanation only unless specifically indicated otherwise.


It will be understood that although the terms first and second are used herein to describe various features or elements, these features or elements should not be limited by these terms. These terms are only used to distinguish one feature or element from another feature or element. Thus, a first feature or element discussed below could be termed a second feature or element, and similarly, a second feature or element discussed below could be termed a first feature or element without departing from the teachings of the present invention.


Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the specification and relevant art and should not be interpreted in an idealized or overly formal sense unless expressly so defined herein. Well-known functions or constructions may not be described in detail for brevity and/or clarity.


The term “about”, as used herein with respect to a value or number, means that the value or number can vary, for example, by +/−20%, +/−10%, +/−5%, +/−1%, +/−0.5%, or even +/−0.1%.


The term “headset”, as used herein, is intended to include any type of device or earpiece that may be attached to or near the ear (or ears) of a user and may have various configurations, without limitation. Headsets incorporating optical sensor modules, as described herein, may include mono headsets (a device having only one earbud, one earpiece, etc.) and stereo headsets (a device having two earbuds, two earpieces, etc.), earbuds, hearing aids, ear jewelry, face masks, headbands, and the like. In some embodiments, the term “headset” may include broadly headset elements that are not located on the head but are associated with the headset. For example, in a “medallion” style wireless headset, where the medallion comprises the wireless electronics and the headphones are plugged into or hard-wired into the medallion, the wearable medallion would be considered part of the headset as a whole. Similarly, in some cases, if a mobile phone or other mobile device is intimately associated with a plugged-in headphone, then the term “headset” may refer to the headphone-mobile device combination.


The terms “optical source” and “optical emitter”, as used herein, are interchangeable.


The term “monitoring” refers to the act of measuring, quantifying, qualifying, estimating, sensing, calculating, interpolating, extrapolating, inferring, deducing, or any combination of these actions. More generally, “monitoring” refers to a way of getting information via one or more sensing elements. For example, “blood health monitoring” may include monitoring blood gas levels, blood hydration, and metabolite/electrolyte levels, etc.


The term “physiological” refers to matter or energy of or from the body of a creature (e.g., humans, animals, etc.). In embodiments of the present invention, the term “physiological” is intended to be used broadly, covering both physical and psychological matter and energy of or from the body of a creature. However, in some cases, the term “psychological” is called-out separately to emphasize aspects of physiology that are more closely tied to conscious or subconscious brain activity rather than the activity of other organs, tissues, or cells.


The term “body” refers to the body of a subject (human or animal) that may wear a device incorporating one or more optical sensor modules, according to embodiments of the present invention.


The term “coupling”, as used herein, refers to the interaction or communication between excitation light entering a region of a body and the region itself. For example, one form of optical coupling may be the interaction between excitation light generated from an optical sensor module and the blood vessels of the body of a user. In one embodiment, this interaction may involve excitation light entering the ear region and scattering from a blood vessel in the ear such that the intensity of scattered light is proportional to blood flow within the blood vessel.


The term “processor” is used broadly to refer to a signal processor or computing system or processing or computing method which may be localized or distributed. For example, a localized signal processor may comprise one or more signal processors or processing methods localized to a general location, such as to a wearable device. Examples of such wearable devices may comprise an earpiece, a headset, a headpiece, a finger clip/band, a toe clip/band, a limb band (such as an arm band or leg band), an ankle band, a wrist band, a nose band, a sensor patch, or the like. Examples of a distributed processor include “the cloud”, the internet, a remote database, a remote processor computer, a plurality of remote processors or computers in communication with each other, or the like, or processing methods distributed amongst one or more of these elements. The key difference is that a distributed processor may include delocalized elements, whereas a localized processor may work independently of a distributed processing system. As a specific example, microprocessors, microcontrollers, ASICs (application specific integrated circuits), analog processing circuitry, or digital signal processors are a few non-limiting examples of physical signal processors that may be found in wearable devices.


The term “remote” does not necessarily mean that a remote device is a wireless device or that it is a long distance away from a device in communication therewith. Rather, the term “remote” is intended to reference a device or system that is distinct from another device or system or that is not substantially reliant on another device or system for core functionality. For example, a computer wired to a wearable device may be considered a remote device, as the two devices are distinct and/or not substantially reliant on each other for core functionality. However, any wireless device (such as a portable device, for example) or system (such as a remote database for example) is considered remote to any other wireless device or system.


Sensor modules, according to embodiments of the present invention may be integrated into various wearable devices including, but not limited to headsets (e.g., earbuds, etc.), wristbands, arm bands, leg bands, rings, patches, etc.


Referring to FIG. 2, an optical sensor module 20 that may be incorporated into a wearable device according to some embodiments of the present invention is illustrated. The illustrated sensor module 20 includes a substrate or base 22 (e.g., a circuit board, etc.) having an optical source 24 and an optical detector 26. As would be understood by one skilled in the art of the present invention, the base 22 may support and/or be connected to various electronic components including, but not limited to, a signal processor, a wireless module for communicating with a remote device, a memory storage device, etc. Moreover, a battery, such as a lithium polymer battery or other portable battery, may be mounted to or connected to the base 22 and may be charged via a charge port, such as a USB charge port, for example. Additionally, the base 22 may be flexible, may be rigid, or may include a combination of flexible and rigid material. The base 22 may have various configurations suitable for supporting electronics.


The optical source 24 may be one or more light-emitting diodes (LED), laser diodes (LD), compact incandescent bulbs, micro-plasma emitters, IR blackbody sources, organic LEDs, or the like. The optical detector 26 may be one or more photodiodes, photodetectors, phototransistors, thyristors, solid state devices, optical chipsets, or the like.


A housing 30 is secured to the base 22 and overlies the optical source 24 and optical detector 26. The illustrated housing 30 has a curved outer surface 32 that is configured to engage a particular portion of the body of a user of the sensor module 20 (i.e., a person wearing a device incorporating the optical sensor module 20). For example, in some embodiments, the sensor module 20 may be incorporated into an earbud and the housing outer surface 32 is contoured to matingly engage a particular region of the ear (e.g., the region between the anti-tragus and the concha, the region along the helix or anti-helix of the ear, etc., as illustrated in FIG. 14). However, the housing outer surface 32 may have various shapes and configurations and need not be curved. For example, in some embodiments, the outer surface 32 of the housing may be flat such that the sensor module 20 may be integrated within a wristband.


The term “matingly engage”, as used herein, does not necessarily mean that the housing 30 must physically touch the body of the person; rather, “matingly engage” implies that the housing 30 is designed to optically or optomechanically couple with a particular region of the body or to have a physical structure that compliments a particular region of the body. For example, the housing 30 of FIG. 2 may fit well within an audio earbud and support optical coupling between the anti-tragus and concha of the ear, but a flat housing structure may be more suitable for the housing enabling optical coupling to a person's wrist.


Though FIG. 2 presents a convex (outward-curving) housing 30, a concave (inward-curving) housing 30 may be better suited for other regions of the body. For example, a concave housing 30 may be well-suited for a digit or limb of the body. Additionally, a concave housing 30 may be well-suited for coupling to the ear region behind the ear, adjacent to the earlobe.


The illustrated housing 30 includes a first light guide 40 in optical communication with the optical source 24 and a second light guide 42 in optical communication with the optical detector 26. In addition to supporting the first and second light guides 40, 42, the housing 30 may be configured to enclose and protect the various electronic components mounted to the base 22 from ambient interference (air, humidity, particulates, electromagnetic interference, etc). In some embodiments, the housing 30 may comprise opaque material that prevents light from escaping or entering the light guides 40, 42 laterally (i.e., confines light within the light guides 40, 42 such that light only enters and exits through the respective light guide ends). However, embodiments of the present invention do not require the housing to comprise opaque material.


The first light guide 40 comprises light transmissive material configured to deliver light from the optical source 24 into a region of a body of a user at one or more predetermined locations. The second light guide 40 comprises light transmissive material configured to collect light external to the sensor module 20 and deliver the collected light to the optical detector 26. The first and second light guides 40, 42 may be formed from various types of light transmissive material. In some embodiments, one or both of the first and second light guides 40, 42 may be formed from an elastomeric light transmissive material. In other embodiments, one or both of the first and second light guides 40, 42 may be formed from a substantially rigid light transmissive material. In some embodiments, one or both of the first and second light guides 40, 42 may be formed from a combination of elastomeric light transmissive material and substantially rigid light transmissive material. Exemplary light transmissive materials include, but are not limited to, polycarbonate, acrylic, silicone, glass, metal oxides, polyurethane, etc. In addition, one or both of the first and second light guides 40, 42 may comprise one or more optical fibers.


In some embodiments, a physical optical filter may be disposed along the optical paths R0 and Ri such that only certain wavelengths of light are allowed to leave or enter the sensor module 20. The physical optical filter can be disposed anywhere along the optical path(s), and may be any variety of filters that are well known in the art, as well as new, innovative filters. An optical filter may be composed of polycarbonate, acrylic, silicone, glass, metal oxides, polyurethane, etc. In some embodiments, an optical filter may be a small slab that is placed in the optical path of the optical source 24 and/or optical detector 26 and may be supported by the structure of the sensor module 20. In some embodiments, an optical filter may be integrated with the optical source 24 and/or the optical detector 26. For example, a bandpass filter, such as an interference filter or the like, may be disposed on the top of the optical source 24 and/or optical detector 26. Alternatively (or additionally), an optical filter effect may be integrated within the semiconductor material comprising the optical source 24 and/or optical detector 26, such as by selective ion implantation of certain regions within silicon or by band-gap engineering within compound semiconductors, such as the AlInGaAs or AlInGaN system of semiconductor engineering.


In some embodiments, an optical filter may be integrated within one or more of the light guides 40 and 42. For example, one or both of the first and second light guides 40, 42 may comprise a material having an optically filtering dye or a material which inherently filters one or more wavelengths of light. As one example, either or both of the light guides 40 and 42 may comprise, wholly or partially, a dye therewithin. As one specific example, at least one light guide may comprise a dye, such as an infrared dye designed to block visible wavelengths but pass IR wavelengths. For example, a polycarbonate or acrylic light guide 40 or 42, dyed with Gentex-E800, would facilitate both light-guiding and IR-pass filtering functionality. Alternatively, another example of such an integrated physical optical filter comprises Filtron® absorptive dyes dispersed in polycarbonate and/or acrylic to create an edge or long-pass optical filter. Such materials may be conventionally molded, extruded, and/or fabricated into an optical filter having a variety of shapes. In the case of FIG. 2, at least one light guide may be partially or wholly comprised of such a material, thereby facilitating the combinational purpose of light guiding and optical filtering.


A few additional non-limiting examples of an inherently filtering material includes sapphire, which absorbs some infrared (IR) wavelengths, and glass, which absorbs some ultraviolet (UV) wavelengths. However, various types of filtering material may be utilized, without limitation. In some embodiments, one or both of the light guides 40, 42 may be surrounded or partially surrounded by a cladding/barrier material (not shown) that is configured to at least partially block light from an external source from entering one or both of the light guides 40, 42 at select locations along the light guides 40, 42 and/or at least partially confine light within one or both light guides 40, 42. The cladding/barrier material may be a light blocking material and/or a light reflective material and/or a material that has a higher optical scattering coefficient than the light guiding material of the light guides 40, 42. For example, the cladding material may be a dark (e.g., black, etc.) or silver (or other reflective color) coating, a material with refractive index that differs from the core light guide material, or a texturized light-scattering material on one or more portions of a distal end surface 40c, 42c of one or both of the light guides 40, 42.


The first light guide 40 defines a first axial direction A1, and the second light guide 42 defines a second axial direction A2, as illustrated in FIG. 2. The first axial direction A1 of the first light guide 40 has an angle a1 relative to a plane P1 defined by a surface of the optical source 24 that is less than ninety degrees (90°), and the second axial direction A2 of the second light guide 42 has an angle a2 relative to a plane P2 defined by a surface of the optical detector 26 that is less than ninety degrees (90°). As such, the first and second light guides 40, 42 are positioned within the housing 30 such that they diverge outwardly from the housing 30.


In some embodiments of the present invention, one or both of the first and second light guides 40, 42 may have a generally cylindrical configuration. In other embodiments, one or both of the first and second light guides 40, 42 may have a generally non-cylindrical configuration, e.g., rectangular, triangular, oval, etc.


Each of the first and second light guides 40, 42 has a respective proximal end 40a, 42a and an opposite distal end 40b, 42b. The proximal end 40a of the first light guide 40 is positioned adjacent the optical source 24, and the proximal end 42a of the second light guide 42 is positioned adjacent the optical detector 26. In the illustrated embodiment, the distal end 40b, 42b of the light guides 40, 42 extends slightly outwardly from the housing 30. However, in other embodiments of the present invention, the distal end portion 40b, 42b of one or both light guides 40, 42 may be substantially flush with the housing 30 or may even be recessed within the housing 30.


Light guides that extend from the housing 30 (as opposed to light guides that are flush with the housing 30) may facilitate a higher signal-to-noise (S/N) ratio for biometrically modulated light vs. unwanted optical scatter, because extended light guides may capture more of the desired biometric signal and/or may reject more of the unwanted noise. Namely, in PPG, blood flowing through a blood vessel will cause optical scatter directly or indirectly related to blood flow changes. However, there will also be unwanted optical scatter associated with light bouncing off (i.e., reflecting off) the skin and other body tissues in a manner that is not biometrically modulated (i.e., light that is not interacting with blood flow changes). The desired signal “S” is comprised of light that is biometrically modulated and the noise “N” is comprised of all other scattered light (such as light scattered by skin, other body tissues, motion artifacts, environmental artifacts, etc.). As will be described later, the shape and angle of the light guides may help increase the S/N ratio.


Light guides that are flush with the housing 30 (as opposed to light guides that are extended from the housing 30) may be more aesthetically appealing to those wearing an earbud, armband, or other wearable device form-factor that integrates the sensor module 20. This is because there will be no substantial protrusions that would make the wearable device look much different than a wearable device that does not integrate such a sensor module. Moreover, there may be a higher degree of wearability and comfort associated with flush light guides if there are no protrusions that may potentially generate discomfort after a period of time wearing a device incorporating the sensor module 20.


The distal end 40b, 42b of each illustrated light guide 40, 42 has a respective exposed end surface 40c, 42c that is configured to engage (or be positioned adjacent or near) a portion of the body B of a user. In some embodiments, the end surface 40c, 42c of one or both of the light guides 40, 42 may have a curved configuration. For example, FIG. 3A illustrates a rounded end surface 40c of the first light guide 40 of the sensor module 20 of FIG. 2. In other embodiments, the end surface 40c, 42c of one or both of the light guides 40, 42 may have a flat configuration. However, the end surface 40c, 42c of one or both of the light guides 40, 42 may be shaped in a variety of ways to couple light to and from the body of a user. For example, a rounded surface may improve light collection from a wider angle and a flat surface may narrow the field of view of the light guide. In some cases, a wider field of view may be important to measure more light from a broader range along the body, but in other cases, a narrower view may be important to focus the field of view on a specific region of the body. Note that the bottom 40d of the light guide 40 of FIG. 3A is at an angle with respect to the top 40c of the light guide 40. Although only light guide 40 is illustrated in FIG. 3A, it is understood that the other light guide 42 may have a bottom portion that is at an angle with respect to a top portion thereof. This alteration of symmetry may provide better coupling of light from/to the optical source 24/optical detector 26 to/from the respective light guide 40, 42 while simultaneously directing the respective light paths at the angles a1 and a2 (FIG. 2).


In some embodiments, the end surface 40c, 42c of one or both of the light guides 40, 42 may be textured with a non-optically smooth finish such as an SPI (Society of Plastics Industry) B-1 finish, or the like. However, other finish texturing may be used in accordance with embodiments of the present invention including, but not limited to, SPI A-1, SPI A-2, SPI A-3, SPI B-2, and SPI B-3. However, embodiments of the present invention do not require surface texturing of the end surfaces 40c, 42c.



FIG. 3B illustrates the optical impact of a textured end surface 40c of the light guide 40 of the sensor module 20 of FIG. 2. A textured surface can cause a “feathering” or “diffusing” of light from the optical source 24, thereby limiting the light that reflects directly from the tissue and into the optical detector 26. A diffuse optical beam may also be more uniform than a beam of light generated by the optical source 24. Diffused light beams may have an intensity distribution that is less sensitive to body motion and may be useful in alleviating motion artifacts in scattered light coming from the body and detected by the optical detector 26. The texturing features in this particular example of FIG. 3B were generated with an average texturing feature size smaller than about 100 μm, and the diameter of the light guide was about 3 mm.


The angled configuration of the first and second light guides 40, 42 prevents most or all light from the optical source 24 from directly reaching the optical detector 26 (i.e., without passing through a portion of the body of a user first) when the outer surface 32 of the housing 30 is separated from the body of a user, for example, by a distance up to about three tenths of a centimeter (0.3 cm) or more. This is illustrated in FIG. 2 wherein the dotted line B is representative of the body (i.e., the skin) of a user. Distance D1 represents the distance from the body B to the outer surface 32 of the housing 30. Rays of light emanating from the optical source are represented by Ro and rays of light detected by the optical detector are represented by Ri. The light rays Ro emanating from the optical source 24 do not overlap with the light rays Ri returning to the optical detector 26 over the distance D1, as represented by distance D2. As such, the light emanating from the optical source 24 is directed along the most physiologically meaningful signal pathway (i.e., through the body B and without substantial, unwanted reflection from the body B into the optical detector 26).


Referring to FIG. 4, a sensor module 20, according to some embodiments of the present invention, may include multiple optical sources 24 and/or multiple optical detectors 26 and, as such, multiple light guides 40, 42 may be utilized. In the illustrated embodiment of FIG. 4, a respective light guide 40 is in optical communication with each of the two optical sources 24, and a respective light guide 42 is in optical communication with each of the two optical detectors 26. The light guides 40, 42 each have respective axial directions A1, A2 that diverge outwardly, as discussed above with respect to FIG. 2. Although FIG. 4 shows light guide arrays are aligned in line with respect to each other, it should be understood that the arrays of light guides may be distributed across a common plane or even in multiple planes, and a linear array is not required for embodiments of the present invention.



FIG. 5 illustrates how effective a sensor module, such as the sensor module 20 of FIG. 2, may be in reducing the effect of noise as a result of movement of the sensor module 20 relative to the body B of a user. The separation distance between sensor module housing outer surface 32 and the body of a user B is represented by D1 in FIG. 2, and is plotted along the “X” axis of FIG. 5. The signal detected by the optical detector 26 is plotted along the “Y” axis of FIG. 5 and varies with the distance D1. The signal is shown in FIG. 5 based on this separation distance (Sensor-tissue separation distance, mm). When a conventional sensor module with no light guides is used, the signal onset with small separation distances is abrupt (namely, the slope is higher), leading to a substantial amount of motion artifact noise in the physiological signal (represented by curve 50). When the sensor module 20 of FIG. 2 is used with flush, non-textured light guides 40, 42, the signal onset with separation is much less abrupt (namely, the slope is lower), as illustrated by curve 52. When the sensor module 20 of FIG. 2 is used with light guides 40, 42 having respective end surfaces 40c, 42c that are textured, the signal onset with sensor-tissue separation is very slow (namely, the slope is lowest), leading to much less physiological movement-associated noise, as illustrated by curve 54. FIG. 5 illustrates the robustness of the sensor module 20 of FIG. 2 against noise in a physiological signal detected by the optical detector 26. Thus, although it is true that curve 50 shows a higher overall signal than that of curve 52 and 54, the slope of curve 50 is much higher as the sensor module separates from the skin of the user, showing that the use of light guides can reduce motion artifacts. Furthermore, generally speaking, a higher S/N as well as lower motion artifact sensitivity will result in the best performing PPG sensor modules.


Referring to FIG. 6, another way to model the robustness of the sensor module 20 of FIG. 2 against physiological signal noise is to perform a “sweep test”. The sweep test involves sweeping either a light source 60 over the optical detector 26 or sweeping an optical detector 62 over the optical source 24. The response signal(s) of the optical detector 24 as a function of the angle of the light source 60 is recorded and the response of the optical detector 62 as a function of the angle of the optical detector 62 is recorded.


The result of such a sweep test is illustrated in FIG. 7 for a sensor module without light guides, for a sensor module, such as sensor module 20 (FIG. 2) with light guides with flush, un-textured end surfaces 40c, 42c, and for a sensor module, such as sensor module 20 (FIG. 2) with textured end surfaces 40c, 42c. In FIG. 7, sweep angle in degrees is plotted along the “X” axis, and signal response is plotted along the “Y” axis. In FIG. 7, zero degrees (0°) represents a direction normal (“normal direction”) to the planes P1, P2 of the surfaces of the optical source 24 and the optical detector 26. Similarly, thirty degrees (30°) in FIG. 7 represents an angle that is 30° between the “normal direction” and the emission angle of the light source used for the sweep test. As can be seen with the recorded signal vs. sweep angle, the signal has a much gentler onset with sweep towards the normal (i.e., 0°) with light guides (in this case the light guides may be referred to as “light pipes”) 40, 42 having textured end surfaces 40c, 42c, as represented by curve 70, and with light guides 40, 42 with flush, un-textured end surfaces 40c, 42c, as represented by curve 74. Within the angle of interest, which are the angles of about ±30°, the signal onset is much steeper without the use of light guides, as represented by curve 72. This steep onset in signal is a source of motion-artifact noise that can be remedied by the use of light guides, according to embodiments of the present invention. Note that in FIG. 7 the total overall signal is highest without light guides, but because the change in signal with angle is so high, the ultimate S/N ratio favors using light guides. This is because the noise (Nm) resulting from motion artifacts can be many times that of the PPG signal associated with biometrically modulated light.



FIG. 8 illustrates an embodiment of the sensor module 20 of FIG. 2 incorporated into a ring device 80 that is configured to be worn around a digit of a user, according to some embodiments of the present invention. The light guides 40, 42 of the sensor module 20 are angled away from each other to prevent the overlap of light rays leaving the optical source 24 from directly entering the optical detector 26. A battery (e.g., a flexible battery) 84 is located within the band 82 of the ring device 80 to provide electrical power to the sensor module 20.


It should be noted that the sensor module 20 may be integrated into the ring device 80 in additional ways in accordance with embodiments of the present invention. For example, the sensor module 20 may be partially within the ring device 80 rather than wholly within the ring device 80 as shown in FIG. 8. Additionally, the light guides 40, 42 may extend or partially extend the length of the outer-inner diameter length (the length that is the difference between the outer and inner diameter of the ring device 80) or the light guides 40, 42 may protrude from the ring device 80 itself. Additional configurations may be used where the light guides 40, 42 direct light at angles relative to each other (e.g., angles a1 and a2 illustrated in FIG. 2). Also, it should be noted that the ring device 80 may be used for not only a finger ring but for any appendage or rounded form-factor, such as a digit or limb, such as a toe, arm, wrist, leg, a neck, a waist, and the like. The strap or band 82 may have different sizes and/or shapes depending on the location of donning (i.e., the location on the body of a subject where the device 80 is worn).


Referring to FIGS. 9A-9B, 10A-10B, and 11A-11B, embodiments of the present invention utilizing a smartphone 100 or other mobile or electrical device are illustrated. The illustrated smartphone 100 includes an optical sensor module 110 that is in proximity to, or integrated within, the camera optics of the smartphone 100 or another optical emitter/detector already on the smartphone 100. The optical sensor module 110 is coupled to an optical module 120 in a wearable structure 130 (such as an armband, wristband, leg band, ring, etc.). This embodiment can be useful for the case when electronics are not desired to be within the wearable structure itself—for example, optical module 120 may be optics within a phone armband strap, where the smartphone 100 may contain all the electronics but may not have the optomechanics for biometric monitoring itself. The optical sensor module 110 may have light guides within it or it may not. For example, as illustrated in FIG. 9B, the optical module 110′ includes only a single window W with perhaps a barrier 112 between the optical source 24 and the optical detector 26. The barrier 112 may protrude all the way to the surface of the window W or it may be shorter. The benefit of having the barrier 112 protrude to the surface of the window W is that doing so may reduce or eliminate cross-talk between the optical source 24 and optical detector 26.


The illustrated optical modules 110, 120, 140 include light guides 40, 42 as described above with respect to the sensor module 20 of FIG. 2. When the optical modules 110 and 120 (and 140, when utilized) are in alignment (as expressed by the dotted lines in FIG. 9A), light (e.g., from the flash associated with the camera of the smartphone 100) can be coupled from the smartphone 100 to the body of the person and back from the body to the smartphone 100, such that stable optical monitoring of the body can be achieved. The light guides 40, 42 in the optical module 120 may be configured to be adjacent or proximate to the skin of a user and may be angled away from each other to prevent the overlap of light rays leaving the optical sources 24 and directly entering the optical detectors 26, as described above.


In the embodiment illustrated in FIGS. 10A-10B, the optical module 120 has multiple light guides 40, 42 that align with a respective multiple light guides 40, 42 of the sensor module 110. The light guides 40, 42 of the sensor module 110 are substantially orthogonal to the respective optical emitters 24 and optical detectors 26, as illustrated. However, the light guides 40, 42 of the optical module 120 are angled such that they diverge from each other, as illustrated. This angled configuration of the light guides 40, 42 in the optical module 120 prevents most or all light from the optical sources 24 from directly reaching the optical detectors 26 without first passing through a portion of the body of a user.


Other coupling configurations and light-guiding configurations for the optical module 120 may be used in embodiments of the present invention, and the light guides of the module 120 do not need to be angled as shown in FIGS. 10A-10B. However, the benefits of angling have been disclosed herein. Additionally, the light guides 40, 42 may be cylindrical, oval, or elliptical (i.e., have circular, oval, or elliptical cross-sections) to prevent unwanted scattering at the edges. However, having light-guiding cross-sections with “sides” or “angles”, such as the case for polygonal light guide cross-sections, may be useful for matching the coupling between the modules 110 and 120.


A benefit of the configuration presented in FIG. 9A is that the optical module 120 may reside in a wearable band (or apparel item) 130 without any need for supporting electronics or battery power in the wearable band 130, as the optical emission and detection may take place via the electronics/optics of the electrical device 100 (such as a smartphone, smartwatch, smartearbud, smartsensor, or other electrical apparatus that is light-weight enough to be attached to and worn on the body of a person). The wearable band 130 may be a ring, an armband (as shown), wristband, legband, neckband, or any band or apparel item such as an item of clothing (shirts, socks, under-garments, etc.) that can be worn along the body but which can also support the optical module 120. Many different kinds of band materials and fabrics may be used, such as plastic, polymers, metals, rubbers, silicones, cotton, nylon, wood, or any other sturdy materials that can be worn for a period of time by subjects. However, the wearable band 130 should be stabilized along the body for accurate physiological readings to be assessed on a continuous basis. This may be achieved by using a stretchable material that can fit firmly along the body and/or by integrating a securing mechanism such as a buckle, clamp, clasp, button, etc., and/or by employing a springing or clamping method to hold both modules in place along the body, using one or more body regions for mechanical support. The optical module 120 does not need to touch the skin in order to generate physiological information, but the optical module 120 typically will perform best when stabilized with respect to the body of the subject.


An additional benefit of the configuration shown in FIG. 9A is that the configuration allows for novel biometric sensing use cases via selective biometric analysis. Namely, if the electrical device 100 is configured to have optics 110 that comprises both a camera module (such as smartphone CCD camera optics, for example) as well as PPG module (such as an optical emitter and an accompanied optical detector), and a processor communicating with both the camera module and the PPG module, then advanced biometric sensing may be achieved, such as selective biometric analysis. In this methodology, images of the body of the subject may be collected and analyzed by the processor with respect to blood flow as sensed by the PPG module. For example, the processor may identify the frequency of blood flow (i.e., the frequency relating to the heart rate or breathing rate) via sensor data from the PPG module and may analyze images sensed by the camera module with respect to this frequency. In this method, pixels that are changing at the same rate (or approximate same rate) as the blood flow frequency may be selectively amplified with respect to pixels that are not changing at this rate (raising the effective contrast). In this way, blood vessels (arteries, veins, arterioles, capillaries, and the like) may be selectively analyzed to generate biometric assessments, even in noisy environments.


According to some embodiments of the present invention, the process can be executed in reverse such that regions of the body that do not substantially modulate with blood flow may be selectively amplified with respect to regions that do modulate with blood flow. These more static regions (such as certain tissue regions comprising bone, skin, tendons, etc.) may then be selectively analyzed.


The above-described selective amplification may be further enhanced by incorporating active motion-artifact removal by using a motion sensor (such as an accelerometer or other motion sensor) in physical communication with the body, smart device 100, and/or wearable band as a noise reference such that the processor, in communication with the motion sensor, is able to selectively remove or attenuate frequencies associated with body motion or other unwanted motion noise. Because many smartphones and other smart devices may comprise both digital cameras and accelerometers (often having multiple axes), the processor (which may also reside in a smartphone) may have access to all of these electronics.


There are several examples of biometric assessments that may be generated by the selective amplification method described above. For example, by ratioing intensities of two (2) or more wavelengths from the selectively amplified pixels, an assessment of blood analyte along each blood vessel may be generated. An example of such blood analyte may include any optically interacting blood analyte, such as blood hemoglobin (oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin, and methemoglobin, for example), bilirubin, lactate, glucose, and the like. Numerous blood chromophores may be analyzed via this method. In the case of glucose and other blood analyte which are not chromophores, adding one or more polarizers to the optics (110, 120) may be required, as glucose and other blood constituents have been observed to preferentially scatter light at certain polarizations. As yet another example of a biometric assessment using selective amplification, a processor may analyze blood vessels along their pathways to see how they change shape with each pulse. This assessment may be used to assess vascular compliance and/or blood pressure along the vessels or to assess cardiac output by assessing these localized blood vessel changes in relation to a physical model. As yet another example of a biometric assessment using selective amplification, a processor may characterize static (not time-varying) and/or dynamic (time-varying) changes in blood vessels to generate a biometric identification of a subject. In this assessment, a processor may compare the blood vessel characterization with a known characterization stored in memory, for example, by running an algorithm to assess their similarity. A similarity above a certain threshold may then trigger an identification for a subject. It is important to note that a key aspect of embodiments of the present invention is that combining a PPG sensor with a camera affords the ability to generate a contrast between physiological properties/characteristics that modulate with blood flow and other properties/characteristics that do not substantially modulate with blood flow.


This selective amplification method may be executed with or without modulating the PPG sensor light source (the optical emitter) or with or without polling the PPG detector and/or the camera. For example, a PPG sensor may be operating in a continuous mode, and PPG readings as well as camera readings may be collected continuously. Alternatively, a PPG sensor may be pulsed to generate pulses of light, or the PPG detector or the camera readings may be polled at time intervals. If multiple wavelengths are employed with the PPG sensor, then alternately modulating (i.e., pulsing) the optical emitters such that only one emitter is on at a time may help differentiate the PPG signals for each wavelength. However, this effect may also be achieved by continuously emitting all optical emitting wavelengths and differentiating signals from each wavelength via optical filters on the camera and/or the optical detector(s) of a PPG sensor. For example, the optical detectors of a PPG sensor may each comprise one or more optical filters to pass only certain wavelengths of light and the camera may comprise optical filters and/or may comprise beam-splitting optics to direct certain optical wavelength ranges to certain light-detecting regions of the camera.


In some embodiments, an optomechanical coupler 140 (FIGS. 9A and 11A-11B) can be used to interface between optical sensor module 110 and optical module 120 such that the two optical modules 110, 120 can be matched or to provide additional stability between the smartphone optical module 110 and the band optical module 120. This may be advantageous where a smartphone 100 has native optomechanics 110 (such as the optics used for a photographic camera and/or optics used to measure heart rate) that may not directly match with the optomechanics of the band 120. In this case, the coupling optomechanics 140 can be used to translate between the optics 110 and 120.


In the embodiment illustrated in FIG. 11A, the optomechanical coupler 140 has light guides 40, 42 with a similar shape and configuration as the sensor module 110. In the embodiment illustrated in FIG. 11B, the coupler 140 has light guides 40, 42 with shapes at one end that conform with shapes of the light guides 40, 42 of the sensor module 110, and with different shapes at the opposite end that conform with shapes of the light guides 40, 42 of the optical module 120. The coupler 140 is designed to couple with the optics on a smart device (illustrated as a smartphone 100 in FIG. 9A) and the optics in the wearable sensor (130, FIG. 9A). As such, a user can utilize a separate coupler 140 for each smartphone or other device that they use, since each smartphone/device may be manufactured using different optics.



FIGS. 12A-12F illustrate another style of the optical sensor module 20 of FIG. 2 that can be used with various wearable monitoring devices, such as earbud monitoring devices. The illustrated sensor module 20 includes a substrate or base 22 (e.g., a circuit board, etc.) having an optical source 24 and an optical detector 26 on one side 22a thereof. The base 22 may support and/or be connected to various electronic components including, but not limited to, a signal processor, a wireless module for communicating with a remote device, a memory storage device, etc. Moreover, a battery, such as a lithium polymer battery or other portable battery, may be mounted to or connected to the base 22 and may be charged via a charge port, such as a USB charge port for example. Additionally, the base 22 may be flexible, rigid, or a combination of flexible and rigid material, or various other base constructs suitable for supporting electronics. The base 22 may comprise one piece or a plurality of pieces. In the illustrated embodiment, a capacitor 24c for driving the optical source 24 and an accelerometer 27 are mounted to an opposite side 22b of the base 22.


The optical source 24 may be one or more light-emitting diodes (LED), laser diodes (LD), compact incandescent bulbs, micro-plasma emitters, IR blackbody sources, or the like. The optical detector 26 may be one or more photodiodes, photodetectors, phototransistors, thyristors, solid state devices, optical chipsets, or the like.


A housing 30 is secured to the base 22 and overlies the optical source 24 and optical detector 26. The illustrated housing 30 has a curved outer surface 32 that is configured to engage a particular portion of the body of a user wearing a device incorporating the sensor module 20. For example, although the sensor module 20 may be integrated into numerous wearable form-factors that afford proximate location of the sensor module to the skin of the user, in some embodiments, the sensor module 20 may be incorporated into an earbud and the housing outer surface 32 is contoured to matingly engage a particular region of the ear (e.g., the region between the anti-tragus and the concha, the region along the helix or anti-helix of the ear etc.). However, the housing outer surface 32 may have various shapes and configurations and need not be curved. For example, a wristband module applying the invention may have a flat housing outer surface 32.


The housing 30 includes a first light guide 40 in optical communication with the optical source 24 and a second light guide 42 in optical communication with the optical detector 26. In addition to supporting the first and second light guides 40, 42, the housing 30 may be configured to enclose and protect the various electronic components mounted to the base 22 from ambient interference (air, humidity, particulates, electromagnetic interference, etc).


The first light guide 40 defines a first axial direction A1, and the second light guide 42 defines a second axial direction A2. The first axial direction A1 of the first light guide 40 has an angle a1 relative to a plane P1 defined by a surface of the optical source 24 that is less than ninety degrees (90°), and the second axial direction A2 of the second light guide 42 has an angle a2 relative to a plane P2 defined by a surface of the optical detector 26 that is less than ninety degrees (90°). As such, the first and second light guides 40, 42 are positioned within the housing 30 such that they diverge outwardly from the housing 30.


Referring now to FIGS. 13A-13D, an earbud speaker driver 300 with integrated optomechanics, according to some embodiments of the present invention, is illustrated. The speaker driver 300 has opposite front and rear portions 302a, 302b. As understood by those skilled in the art, sound is emitted through apertures 306 formed in the front portion 302a of the speaker driver 300. An optical source 24 and optical detector 26 are supported by a printed circuit board (PCB) 304 on the rear portion 302b of the speaker driver 300. Light guides 40, 42 couple from the optical source 24 and optical detector 26 to a select region of the ear. In one particular embodiment, the light guides lead to a sensor module that may be placed between the anti-tragus an concha of the ear, such as the sensor module 304 in FIG. 13D. The light guides 40, 42 may lead to any region of the ear, such as the ear canal, tympanic membrane, earlobe, helix, anti-helix, tragus, behind the ear, temple, etc.


A key benefit of the illustrated speaker driver 300 of FIGS. 13A-13D is that all the sensor electronics may be integrated into a compact speaker driver or speaker driver assembly, rather than dispersed throughout an earbud, and the light guiding may be used to couple from the speaker driver 300 to numerous locations of the ear. Additional sensor electronics and light guiding may also be located on the speaker driver 300. For example, the PCB 304 may support an accelerometer, humidity sensor, altimeter, proximity sensor, temperature sensor, etc. Moreover, the PCB 304 may house a temperature sensor coupled to a light guide that directs black body radiation from the tympanic membrane to the temperature sensor. In this case, the temperature sensor may preferably comprise at least one thermopile and one thermistor.



FIG. 14 is an illustration of a human ear E with various portions thereof labeled. FIGS. 15-17, 18A-18B, 19, 20, 21A-21B and 22A-22B show various embodiments of speaker drivers 300 integrated with biometric sensors or both biometric sensors and light guides. It should be noted that the speaker drivers 300 may be integrated within earbuds or other earpieces, or other headwear, but the earbuds are not shown to promote clarity of the invention and to highlight the fact that the speaker drivers 300 may be integrated into a variety of different earbuds, earpieces, headwear, and the like. Additionally, the sizes of various elements may not be to scale. For example, light guides (e.g., 40, 42, FIGS. 17, 19) may be shown smaller, larger, differently shaped than may be in an actual device in order to help present certain aspects of the invention more clearly in the figures.


In FIGS. 15-20, a speaker driver 300 is shown without an earbud housing, as the speaker driver 300 may be incorporated in a variety of earbud designs. The speaker driver 300 is shown positioned within an ear E of a subject and has a sensor circuit 312. In the embodiment illustrated in FIG. 15, the speaker driver 300 is positioned near the concha of the ear E, for example between the antihelix and the tragus of the ear E. A flex circuit (or other electrical connection medium) 310 is electrically connected to the speaker driver 300 and extends from the speaker driver 300. The flex circuit 310 supports a sensor circuit 312 that includes an optical emitter 24 and optical detector 26. The flex circuit 310 provides a signal path from/to the sensor circuit 312 and speaker driver 300. In FIG. 15, the speaker driver 300 is illustrated slightly higher in the concha than would be normal in order to be able to illustrate the sensor circuit 312.


The flex circuit 310 is configured such that sensor circuit 312 touches the skin of the ear at a region containing blood vessels, such as the concha, anti-tragus, ear canal, anti-helix, helix, earlobe, behind the ear, and the like. Performance may be best when the sensor circuit is located at the anti-tragus and/or concha, including (but not limited to) the intersection of the anti-tragus and concha of the ear E. In the illustrated embodiment, the earbud wire 314 (i.e., the electrical wire providing sound to the earbud speaker driver 300, as well as providing electrical connectivity to the sensor circuit 312) is connected to the flex circuit 310. The flex circuit 310 is configured to dampen sound vibrations from the speaker driver 300 and to provide tight coupling of the sensor circuit 312 to the skin.


In the embodiment illustrated in FIG. 16, the speaker driver 300 is positioned near the concha of the ear E, for example between the antihelix and the tragus of the ear E. A rigid sensor circuit 312 that includes an optical emitter 24 and optical detector 26 is secured to the speaker driver 300 and is electrically connected to the speaker driver 300. In the illustrated embodiment, the sensor circuit 312 is oriented to touch the skin behind the antitragus of the ear E (the skin between the anti-tragus and concha of the ear E), but other locations of the ear are also appropriate. Damping material 316 is positioned between the sensor circuit 312 and the speaker driver 300, as illustrated. The damping material 316 dampens sound vibrations from the speaker driver 300 and provides cushioned coupling with the skin of the ear E. In the illustrated embodiment, the earbud wire 314 is connected to the sensor circuit 310 and to the speaker driver 300. In FIG. 16, the speaker driver 300 is illustrated slightly higher in the concha than would be normal in order to be able to illustrate the light guides 40, 42 and sensor circuit 312.


In the embodiment illustrated in FIG. 17, the speaker driver 300 is positioned near the concha of the ear E, for example between the antihelix and the tragus of the ear E. A sensor circuit 312 that includes an optical emitter 24 and optical detector 26 is secured to the speaker driver 300 and is electrically connected to the speaker driver 300. A pair of light guides 40, 42 are in optical communication with the optical emitter 24 and optical detector 26, and a distal end of each is configured to engage the skin behind the antitragus of the ear E. Light guide 40 guides light from the optical emitter into the skin and light guide 42 collects light scattered within the ear and delivers this to the optical detector 26. In some embodiments, damping material (not shown) may be positioned between the sensor circuit 312 and the speaker driver 300 to dampen sound vibrations from the speaker driver 300. In the illustrated embodiment, the earbud wire 314 is connected to the sensor circuit 310. Although only two light guides 40, 42 are illustrated in FIG. 17, it is understood that more than two light guides may be utilized.


In the embodiment illustrated in FIG. 18A, the speaker driver 300 is positioned within the ear E, for example between the antihelix and the tragus of the ear E. A flex circuit 310 containing an optical emitter 24 and detector 26 is electrically connected to the speaker driver 300 and extends from the speaker driver 300 into the ear canal. The emitter 24 and detector 26 are configured to emit and detect light along the skin of the ear canal and/or the tympanic membrane. As illustrated in FIG. 18B, the speaker driver 300 includes pads 320 for electrically connecting to the speaker wire and pads for electrically connecting to the flex circuit 310.


The flex circuit supports a sensor circuit 312 that includes an optical emitter 24 and optical detector 26. The flex circuit 310 provides a signal path from/to the sensor circuit 312 and speaker driver 300. The flex circuit 310 is configured to dampen sound vibrations from the speaker driver 300 and to provide tight coupling of the sensor circuit 312 to the skin within the ear canal. In the illustrated embodiment, the earbud wire 314 is connected to the speaker driver 300.


In the embodiment illustrated in FIG. 19, the speaker driver 300 is positioned within the ear E, for example between the antihelix and the tragus of the ear E. A sensor circuit 312 that includes an optical emitter 24 and optical detector 26 is secured to the speaker driver 300 and is electrically connected to the speaker driver 300. Damping material 316 is positioned between the sensor circuit 312 and the speaker driver 300 to dampen sound vibrations from the speaker driver 300. A pair of light guides 40, 42 are in optical communication with the optical emitter 24 and optical detector 26, and the light guides 40, 42 are configured to extend into the ear canal and engage the skin in the ear canal and/or the tympanic membrane. Light guide 40 guides light from the optical emitter into the ear and light guide 42 collects light scattered within the ear and delivers this to the optical detector 26. In the illustrated embodiment, the earbud wire 314 is connected to the speaker driver 300. In FIG. 19, the light guides 40, 42 are configured to direct light linearly between the emitter 24 and detector 26 and the ear E. Also, the emitter light is directed towards the concha of the ear and the detector collects light scattered by the concha of the ear.


In the embodiment illustrated in FIG. 20, the speaker driver 300 is positioned within the ear E, for example between the antihelix and the tragus of the ear E. An earbud wire 314 is connected to the speaker driver 300 and to a sensor circuit 312. The sensor circuit 312 is configured to be positioned within the ear canal and includes an optical emitter 24 and optical detector 26.



FIGS. 21A-21B and 22A-22B further illustrate the speaker driver embodiment of FIG. 20 situated near or inside the ear canal. In FIGS. 21A-21B and 22A-22B, the sensor circuit 312 is shown to be configured to be flexibly placed within the ear canal to couple with the ear canal and/or tympanic membrane. An additional flex connection or wire from the audio driver may also be available for additional sensors or actuators, such as at least one mechanical or acoustical actuator and/or microphones. In FIGS. 22A-22B, a structure or brace is shown to support the sensor circuit to keep it integrated together in the ear canal.



FIGS. 23-25 are block diagrams illustrating various configurations of a remote data processing unit 420 in communication with an earbud 400 having a sensor module 20, according to embodiments of the present invention. In each of the embodiments, the earbud 400 includes a speaker driver 300 and a sensor module 20, as described above. In each of the embodiments, the data processing unit 420 includes a processor 422, supporting circuitry 424, and a power source 424, such as a battery, capacitor, power regulating circuitry, energy harvesting power source, and/or a connection to an external power source, as would be understood by one skilled in the art. Data from the sensor module 20 is processed by the data processing unit 420. The data processing unit 420 is configured to communicate with another device via wired or wireless communication.


In the embodiment illustrated in FIG. 23, the processor 422 of the remote data processing unit 420 is in analog communication with the speaker driver 300 and is in digital communication with the sensor module 20.


In the embodiment illustrated in FIG. 24, the processor 422 of the remote data processing unit 420 is in digital communication with the sensor module 20. The sensor module 20 may include a digital to analog converter to provide an audio signal to the speaker driver 300.


In the embodiment illustrated in FIG. 25, the processor 422 of the remote data processing unit 420 communicates with the speaker driver 300 of the earbud 400 via analog communication with an embedded digital signal. In some embodiments, this analog communication may be wired and in others it may be wireless. The embedded digital signal may be “quasi-digital”, as a modulated signal within the analog signal, such that both audio information and biometric sensor information are integrated within the analog signal. Such modulation may be achieved on the earbud 400 itself (as represented by the “+” sign in FIG. 25) using modulation techniques that are well-known by those skilled in the art (see, for example, U.S. Patent Application Publication No. 2014/0140567, which is incorporated herein by reference in its entirety). The data processing unit 420 may be located with the earbud 400 or may be located away from the earbud 400, with analog communication between the data processing unit 420 and the earbud 400. At least part of the functionality of the data processing unit 420 may comprise demodulation of the audio+biometric sensor signals, such that each can be addressed separately for audio communication and biofeedback. The data processing unit 420 may be in wireless or wired communication with an external device or external circuitry. A key benefit of the illustrated embodiment is that it enables the data processing unit 420 to be integrated within a smartphone or other smart device via the analog audio jack of the device, with analog communication to the earbud 400. Thus, a separate digital connection to the smart device would not be required in such a configuration, as both the audio and biometric signals are modulated and demodulated in an analog fashion.



FIG. 26 is a block diagram of an earbud 400 having both a sensor module 20 and data processing capability, according to some embodiments of the present invention. The earbud 400 may include a speaker driver 300 and a sensor module 20, as described above, and may include a processor 422, supporting circuitry 424, and a power source 424, such as a battery or a connection area to access an external power source via a port or through soldering. Data from the sensor module 20 is processed by the processor 422. The processor 422 is configured to communicate with other devices, including another earbud, via wired or wireless communication 428. The processor 422 is in analog communication with the speaker driver 300 and is in digital communication with the sensor module 20.


A key benefit of the embodiment of FIG. 26 is that it enables an integrated earbud unit. Such a design may fit within a “true wireless” wireless stereo headset, where there are two separate earpieces available for each ear, with each earpiece in wireless communication with the other. In such an embodiment, each earpiece may comprise the structure of FIG. 26, such that each earpiece comprises sensors and supports audio communication. Moreover, having the driver circuitry, light-guiding, and sensor circuitry integrated as a unit can help reduce the spacing requirements for such a dual-wireless design, where space is fundamentally limited by the size of a subject's ears.



FIG. 27 illustrates a pair of earbuds 400 according to some embodiments of the present invention. Each earbud 400 includes a speaker driver 300 and sensor module 20, as described above. Each earbud 400 is connected to a remote data processing unit 420, which may include a processor, supporting circuitry, and a power source, as described above. Data from each sensor module 20 is processed by the data processing unit and can be communicated to other devices via wired or wireless communication.



FIG. 28 illustrates an earbud 400 having both a sensor module 20 and data processing capability, according to some embodiments of the present invention. The earbud 400 includes a speaker driver 300 and a sensor module 20, as described above. The earbud 400 also includes a processor 422, supporting circuitry 424, and a power source 426, such as a battery, enclosed within a housing 430. The housing 430 is configured to be supported by the ear of a subject. Data from the sensor module 20 is processed by the processor 422. The processor 422 is configured to communicate with other devices via wired or wireless communication. As described above with respect to FIG. 26, this embodiment may comprise two separate earbuds 400 in wireless communication with each other. Moreover, the electronics may be integrated completely with the earbuds 400 alone, such that earhooks may not be required.



FIGS. 29-31 illustrate a speaker driver 300 having integrated light guiding, with sensor locations positioned in various spots within an ear E of a subject, according to some embodiments of the present invention. These figures show designs where the light guiding couples between the speaker driver 300 and sensor module 20, and wherein the sensor module 20 is located at various regions of the ear E. The light guiding may be supported by the earbud housing (not shown), by adhesive (such as glue or welding byproducts), overmolding, integrated alignment tabs, or the like. To simplify the image to emphasize sensor placement, the separations and barrier regions between the emitter and detector light-guiding is not shown (however, examples are provided in FIG. 12 and FIG. 13). FIG. 29 shows a configuration where the light is guided towards a region of the ear E between the anti-tragus and concha of the ear. FIG. 30 shows a configuration where the light is guided between the anti-helix and concha of the ear E. FIG. 31 shows how the light guiding may be configured, with the sensor module removed for clarity. The light guiding may also be contoured to couple from the sensor elements on the speaker driver 300 to the concha of the ear or other ear location.


In some embodiments, one or both of the light guides 40, 42 may be surrounded or partially surrounded by a cladding/barrier material 112 that is configured to at least partially block light from an external source from entering one or both of the light guides 40, 42 at select locations along the light guides 40, 42 and/or at least partially confine light within one or both light guides 40, 42. The cladding/barrier material 112 may be a light blocking material and/or a light reflective material and/or a material that has a higher optical scattering coefficient than the light guiding material of the light guides 40, 42. For example, the cladding material 112 may be a dark (e.g., black, etc.) or silver (or other reflective color) coating, a material with refractive index that differs from (i.e., is less than) the core light guide material, or a texturized light-scattering material on one or more portions of a distal end surface 40c, 42c of one or both of the light guides 40, 42.



FIGS. 32A-32F illustrate a biometric monitoring device 200 configured to be secured within an ear of a user and that may incorporate the sensor module 20 and light guides 40, 42 described above. The illustrated device 200 includes an earpiece body 202, a sensor module 204, a stabilizer 206, a sound port 208, and a connection point 210. The sensor module 204 includes angled light guides 40, 42 as described above with respect to FIG. 2. The illustrated device 200 is configured to be positioned within an ear of a user so as to reduce movement of the device 200. The various components are designed to matingly engage with specific contact points within an ear. For example, the sensor module 204 is configured to engage the region between the anti-tragus and concha of the ear and the stabilizer is configured to engage the anti-helix.


The illustrated device 200 is designed such that its center of gravity CG (FIGS. 32A-32C) is positioned at a location that provides enhanced stability to the device 200 when positioned within an ear of a user. The illustrated location of the CG helps prevent the device 200 from becoming dislodged from an ear of a user during user movement, including extreme activities, such as running and exercising. Moreover, the location of the CG is such that the device 200 is resistant to rotation when positioned within the ear of a user.


The center of gravity CG of the illustrated device 200 is located along the intersection of orthogonal planes PL1 and PL2 (FIGS. 32D-32F). As illustrated, plane PL2 bisects the center of the sensor module 204 and, in this particular embodiment, the center of gravity CG of the device 200 goes through the middle of the anti-tragus/concha divide in the ear, where the sensor module 204 of the monitoring device 200 is aligned.



FIGS. 33 and 34 illustrate an optical sensor module 20 that can be used with various monitoring devices in proximity to the skin, such as monitoring devices that are integrated into earbuds, armbands, wristbands, rings, patches, eyewear, headbands, and the like, according to some embodiments of the present invention. The illustrated sensor module 20 includes a substrate or base 22 (e.g., a circuit board, etc.) having an optical source 24 and an optical detector 26 on one side 22a thereof. The base 22 may support and/or be connected to various electronic components including, but not limited to, a signal processor, a wireless module for communicating with a remote device, a memory storage device, etc. Moreover, a battery, such as a lithium polymer battery or other portable battery, may be mounted to or connected to the base 22 and may be charged via a charge port, such as a USB charge port for example. Additionally, the base 22 may be flexible, or rigid, or may be formed from a combination of flexible and rigid material, or various other base constructs suitable for supporting electronics. In the illustrated embodiment, a capacitor 24c for driving the optical source 24 and an accelerometer 27 are mounted to an opposite side 22b of the base 22.


The optical source 24 may be one or more light-emitting diodes (LED), laser diodes (LD), organic light-emitting diodes (OLEDs), compact incandescent bulbs, micro-plasma emitters, IR blackbody sources, or the like. The optical detector 26 may be one or more photodiodes, photodetectors, phototransistors, thyristors, solid state devices, optical chipsets, or the like.


A housing 30 is secured to the base 22 and overlies the optical source 24 and optical detector 26. The illustrated housing 30 has a curved outer surface 32 that is configured to engage a particular portion of the body of a user of the sensor module 20. For example, in some embodiments, the sensor module 20 may be incorporated into an earbud and the housing outer surface 32 is contoured to matingly engage a particular region of the ear (e.g., the region between the anti-tragus and the concha, the region along the helix or anti-helix of the ear, the skin of the ear canal, etc.). However, the housing outer surface 32 may have various shapes and configurations and need not be curved. For example, a wristband module applying the invention may have a flat housing outer surface 32.


The housing 30 includes a first light guide 40 in optical communication with the optical source 24 and a second light guide 42 in optical communication with the optical detector 26. In addition to supporting the first and second light guides 40, 42, the housing 30 may be configured to enclose and protect the various electronic components mounted to the base 22 from ambient interference (air, humidity, particulates, electromagnetic interference, etc).


The housing 30 also includes a first light polarizing element 90 in optical communication with the optical source 24, and a second light polarizing element 92 in optical communication with the optical detector 26. The first polarizing light element 90 is configured to polarize light emitted by the optical source 24, and the second light polarizing element 92 is configured to polarize light detected by the optical detector 26. Although illustrated as first and second light polarizing elements 90, 92, in some embodiments, the sensor module 20 may utilize a single polarizing element that is in optical communication with one or both of the optical source 24 and optical detector 26.


In some embodiments, the first and second light polarizing elements 90, 92 have the same light polarization orientation (i.e., parallel planes of polarization). In other embodiments, the first and second light polarizing elements 90, 92 have respective different light polarization orientations. For example, the first and second light polarizing elements 90, 92 may have planes of polarization that are orthogonal (i.e., 90°) to each other.


In some embodiments, one or both of the first and second light polarizing elements 90, 92 may be a light polarizing film. In other embodiments, one or both of the first and second light polarizing elements 90, 92 may be a light polarizing lens. In other embodiments, one or both of the first and second light guides 40, 42 may include light polarizing material that serves the function of light polarizing elements 90, 92.


The illustrated sensor module housing 30 includes first and second windows 33a, 33b of optically transparent material through which light from the optical source passes and through which light detected by the optical detector passes, respectively. In some embodiments, the material of one or both of the first and second windows 33a, 33b may include polarizing material (e.g., a polarizing film, etc.) that serves as a polarizing element. One or both of the first and second windows 33a, 33b may also be configured to act as a lens.


In the illustrated embodiment of FIG. 34, the first and second light polarizing elements 90, 92 are polarizing films. Light Le emitted by the optical source 24 is polarized via the first light polarizing element 90, enters the skin S of a subject being monitored via the sensor module 20 and exits the skin S as modulated light Lm. The modulated light Lm is polarized via the second light polarizing element 92 prior to entering the light detector 26. Some of the polarized light emitted by the light source 24 is reflected off (indicated by Lr) of the skin S of the subject. The second light polarizing element 92 suppresses this reflected light Lr. The modulated light Lm that exits the skin S of the subject tends to be depolarized, and up to 50% of this light will traverse the second light polarizing element 92. In principle, light that is specularly reflected off the skin, which will have little if any desired blood flow (or other physiological) information about the subject wearing the module 20, will be sharply attenuated by a cross-polarization orientation of the first and second light polarizing elements 90, 92, with at least one of the first and second polarizing elements 90, 92 being off-axis with the other by approximately 90-degrees. Thus, during times of high skin motion, such as during running or during other aggressive exercise by the subject wearing the sensor module 20, specularly reflected motion artifacts may be attenuated such that mostly optical scatter signals from below the skin S will reach the optical detector 26.


Any suitable light polarizing material which will produce a light polarization effect may be utilized as the first and second light polarizing elements 90, 92 in the context of the present invention. Exemplary polarizing material that can be used in accordance with embodiments of the present invention is available from American Polarizers, Inc., Reading, Pa., as well as Edmund Optics, Barrington, N.J.


The light-guiding material itself, or the lens material, may comprise polarizing material. Additionally, it should be noted that in some embodiments the polarizing material 90, 92 should be located on the outside of the light guides 40, 42 (as shown in FIG. 35), as the light-guiding itself may be depolarizing, depending on the material used and the structure of the light guide, and hence defeat the purpose of having polarizers at all. In such case, a polarization coating or filter on top of each light guide 40, 42 may be most effective. Such a film can be deposited, textured (etched, machined, imprinted, etc.), laminated, glued, or the like.


Referring now to FIG. 35, a sensor module 20 configured to be worn by a subject according to other embodiments of the present invention is illustrated. The sensor module 20 includes a housing 30 that supports an optical source 24 and an optical detector 26. A barrier 112 may be located between the optical source 24 and the optical detector 26 to reduce or eliminate cross-talk between the optical source 24 and optical detector 26. The housing also supports a first light polarizing element 90 in optical communication with the optical source 24 that is configured to polarize light emitted by the optical source 24, and a second light polarizing element 92 in optical communication with the optical detector 26 that is configured to polarize light detected by the optical source 24. The sensor module 20 may have a similar construction as the sensor module 20 of FIG. 34.


In some embodiments, the first and second light polarizing elements 90, 92 have the same light polarization orientation (i.e., parallel planes of polarization). In other embodiments, the first and second light polarizing elements 90, 92 have respective different light polarization orientations. For example, the first and second light polarizing elements 90, 92 may have planes of polarization that are orthogonal (i.e., 90°) to each other.


In some embodiments, one or both of the first and second light polarizing elements 90, 92 may be a light polarizing film. In other embodiments, one or both of the first and second light polarizing elements 90, 92 may be a light polarizing lens which may couple to light guides (not shown). In other embodiments, the housing 30 may include first and second windows as described above with respect to FIG. 34. In some embodiments, the first and second windows may include polarizing material that serve as the polarizing elements 90, 92.


The illustrated sensor module 20 is secured to a portion of the body B of a subject via a band or strap 34. For example, the body portion B may be a digit, an arm, a leg, a torso, etc., of a subject. Light Le emitted by the light source 24 traverses the light polarizing element 90 and either enters the body B or is reflected off of the surface of the body B. Light that enters the body B scatters multiple times, and is becomes depolarized Lm, such that when it exits the wrist, much of the light Lm can traverse the second light polarizing element 92 and be detected by the light detector 26. Reflected light Lr can be filtered out by the second light polarizing element 92 and can therefore be kept from the light detector 26. As such, the light detector 26 can detect primarily light from the light source 24 that has travelled through the tissue of the body B.


Any suitable light polarizing material which will produce a light polarization effect may be utilized as the first and second light polarizing elements 90, 92 in the context of the present invention.


The foregoing is illustrative of the present invention and is not to be construed as limiting thereof. Although a few exemplary embodiments of this invention have been described, those skilled in the art will readily appreciate that many modifications are possible in the exemplary embodiments without materially departing from the teachings and advantages of this invention. Accordingly, all such modifications are intended to be included within the scope of this invention as defined in the claims. The invention is defined by the following claims, with equivalents of the claims to be included therein.

Claims
  • 1. A headset, comprising: a housing;a speaker driver within the housing;a printed circuit board (PCB) directly mounted on a surface of the speaker driver; anda sensor module supported by the PCB and electrically connected to the speaker driver, wherein the sensor module comprises an optical source and an optical detector, and wherein the sensor module is configured to detect and/or measure physiological information from a subject wearing the headset,wherein the PCB is an elongated, flexible PCB having a distal end portion, and wherein the optical source and optical detector are secured to the PCB at the distal end portion.
  • 2. The headset of claim 1, further comprising a first light guide coupled to the optical source and/or a second light guide coupled to the optical detector, wherein the first light guide is configured to deliver light from the optical source into an ear region of the subject via a distal end thereof, and wherein the second light guide is configured to collect light from the ear region via a distal end thereof and deliver collected light to the optical detector.
  • 3. The headset of claim 1, further comprising at least one of the following secured to the PCB: an accelerometer, a humidity sensor, an altimeter, a temperature sensor.
  • 4. The headset of claim 1, further comprising at least one signal processor secured to the PCB that is configured to process signals produced by the optical detector.
  • 5. The headset of claim 1, wherein the headset is in communication with a data processing unit comprising a processor and supporting circuitry that is configured to process signals produced by the optical detector.
  • 6. The headset of claim 1, wherein the headset is a hearing aid.
  • 7. A speaker driver of an earpiece that is configured to be worn within an ear of a subject, the speaker driver comprising: a first portion configured to emit sounds;a second portion integrated within the first portion; andat least one sensor circuit on the second portion of the speaker driver and electrically connected to the speaker driver, wherein the at least one sensor circuit comprises an optical source and an optical detector, and wherein the at least one sensor circuit is configured to detect and/or measure physiological information from the subject wearing the speaker driver.
  • 8. The speaker driver of claim 7, further comprising damping material positioned between the at least one sensor circuit and the speaker driver, wherein the damping material is configured to dampen sound vibrations from the speaker driver.
  • 9. The speaker driver of claim 7, further comprising at least one light guide optically coupled to the optical source and/or to the optical detector.
  • 10. The speaker driver of claim 7, further comprising at least one light guide optically coupled to the optical source and configured to deliver light from the optical source into an ear region of the subject.
  • 11. The speaker driver of claim 7, further comprising at least one light guide optically coupled to the optical detector and configured to collect light from the ear of the subject and deliver collected light to the optical detector.
  • 12. A speaker driver configured to be worn within an ear of a subject, the speaker driver comprising: a front portion of the speaker driver configured to emit sounds;a rear portion of the speaker driver; andat least one sensor circuit on the rear portion of the speaker driver and electrically connected to the speaker driver, wherein the at least one sensor circuit comprises an optical source and an optical detector, and wherein the at least one sensor circuit is configured to detect and/or measure physiological information from the subject wearing the speaker driver,wherein the rear portion is on an opposite side of the speaker driver from the front portion.
  • 13. The speaker driver of claim 12, further comprising a printed circuit board (PCB) coupled to the speaker driver and the at least one sensor circuit.
  • 14. A monitoring device configured to operate in proximity to an ear of a subject, comprising: a housing;a speaker driver within the housing; anda sensor module that is flexibly coupled to the speaker driver, wherein the sensor module comprises an optical source and an optical detector, and wherein the sensor module is configured to detect and/or measure physiological information from the subject.
  • 15. The monitoring device of claim 14, further comprising a processor and supporting circuitry that is configured to process signals produced by the optical detector.
  • 16. The monitoring device of claim 15, wherein the sensor module is coupled to the processor by an electrical wire.
  • 17. The monitoring device of claim 15, wherein the sensor module is wirelessly coupled to the processor.
  • 18. The monitoring device of claim 14, further comprising at least one light guide optically coupled to the optical detector and configured to collect light from the ear of the subject and deliver collected light to the optical detector.
  • 19. The monitoring device of claim 14, wherein the sensor module is flexibly coupled to the speaker driver via a flex circuit that extends from the speaker driver into an ear canal of the ear of the subject.
  • 20. The monitoring device of claim 19, wherein the flex circuit is configured to dampen sound vibrations from the speaker driver.
RELATED APPLICATIONS

This application is a continuation of U.S. patent application Ser. No. 15/324,139, filed Jan. 5, 2017, which is a 35 U.S.C. § 371 national stage application of PCT Application No. PCT/US2015/041562, filed on Jul. 22, 2015, which claims the benefit of and priority to U.S. Provisional Patent Application No. 62/033,922 filed Aug. 6, 2014, the disclosures of which are incorporated herein by reference as if set forth in their entireties.

US Referenced Citations (481)
Number Name Date Kind
3595219 Friedlander et al. Jul 1971 A
4240882 Ang et al. Dec 1980 A
4331154 Broadwater et al. May 1982 A
4438772 Slavin Mar 1984 A
4491760 Linvill Jan 1985 A
4521499 Switzer Jun 1985 A
4541905 Kuwana et al. Sep 1985 A
4592807 Switzer Jun 1986 A
4655225 Dahne et al. Apr 1987 A
4830014 Goodman et al. May 1989 A
4882492 Schlager Nov 1989 A
4896676 Sasaki Jan 1990 A
4928704 Hardt May 1990 A
4957109 Groeger et al. Sep 1990 A
5002060 Nedivi Mar 1991 A
5022970 Cook et al. Jun 1991 A
5025791 Niwa Jun 1991 A
5079421 Knudson et al. Jan 1992 A
5080098 Willett et al. Jan 1992 A
5086229 Rosenthal et al. Feb 1992 A
5143078 Mather et al. Sep 1992 A
5226417 Swedlow et al. Jul 1993 A
5237994 Goldberger Aug 1993 A
5348002 Caro Sep 1994 A
5377100 Pope et al. Dec 1994 A
5482036 Diab et al. Jan 1996 A
5492129 Greenberger Feb 1996 A
5499301 Sudo et al. Mar 1996 A
5581648 Sahagen Dec 1996 A
5596987 Chance Jan 1997 A
5662117 Bittman Sep 1997 A
5673692 Schulze et al. Oct 1997 A
5697374 Odagiri et al. Dec 1997 A
5711308 Singer Jan 1998 A
5725480 Oosta et al. Mar 1998 A
5743260 Chung et al. Apr 1998 A
5779631 Chance Jul 1998 A
5797841 Delonzor et al. Aug 1998 A
5807114 Hodges et al. Sep 1998 A
5807267 Bryars et al. Sep 1998 A
5853005 Scanlon Dec 1998 A
5904654 Wohltmann et al. May 1999 A
5938593 Quellette Aug 1999 A
5964701 Asada et al. Oct 1999 A
5971931 Raff Oct 1999 A
5974338 Asano et al. Oct 1999 A
5995858 Kinast Nov 1999 A
6004274 Nolan et al. Dec 1999 A
6013007 Root et al. Jan 2000 A
6023541 Merchant et al. Feb 2000 A
6030342 Amano et al. Feb 2000 A
6045511 Ott et al. Apr 2000 A
6067006 O'Brien May 2000 A
6070093 Oosta et al. May 2000 A
6078829 Uchida et al. Jun 2000 A
6080110 Thorgersen Jun 2000 A
6081742 Amano et al. Jun 2000 A
6186145 Brown Feb 2001 B1
6198394 Jacobsen et al. Mar 2001 B1
6198951 Kosuda et al. Mar 2001 B1
6205354 Gellermann et al. Mar 2001 B1
6231519 Blants et al. May 2001 B1
6283915 Aceti et al. Sep 2001 B1
6285816 Anderson et al. Sep 2001 B1
6289230 Chaiken et al. Sep 2001 B1
6298314 Blackadar et al. Oct 2001 B1
6332868 Sato et al. Dec 2001 B1
6358216 Kraus et al. Mar 2002 B1
6361660 Goldstein Mar 2002 B1
6371925 Imai et al. Apr 2002 B1
6374129 Chin et al. Apr 2002 B1
6415167 Blank et al. Jul 2002 B1
6443890 Schulze et al. Sep 2002 B1
6444474 Thomas et al. Sep 2002 B1
6454718 Clift Sep 2002 B1
6458080 Brown et al. Oct 2002 B1
6470893 Boesen Oct 2002 B1
6513532 Mault et al. Feb 2003 B2
6514278 Hibst et al. Feb 2003 B1
6527711 Stivoric et al. Mar 2003 B1
6527712 Brown et al. Mar 2003 B1
6529754 Kondo Mar 2003 B2
6534012 Hazen et al. Mar 2003 B1
6556852 Schulze Apr 2003 B1
6569094 Suzuki et al. May 2003 B2
6571117 Marbach May 2003 B1
6605038 Teller et al. Aug 2003 B1
6616613 Goodman Sep 2003 B1
6631196 Taenzer et al. Oct 2003 B1
6647378 Kindo Nov 2003 B2
6656116 Kim et al. Dec 2003 B2
6694180 Boesen Feb 2004 B1
6745061 Hicks et al. Jun 2004 B1
6748254 O'Neil et al. Jun 2004 B2
6760610 Tschupp et al. Jul 2004 B2
6783501 Takahashi et al. Aug 2004 B2
6808473 Hisano et al. Oct 2004 B2
6859658 Krug Feb 2005 B1
6893396 Schulze et al. May 2005 B2
6941239 Unuma et al. Sep 2005 B2
6953435 Kondo et al. Oct 2005 B2
6996427 Ali et al. Feb 2006 B2
6997879 Turcott Feb 2006 B1
7018338 Vetter et al. Mar 2006 B2
7024369 Brown et al. Apr 2006 B1
7030359 Römhild Apr 2006 B2
7034694 Yamaguchi et al. Apr 2006 B2
7039454 Kaga et al. May 2006 B1
7041062 Friedrichs et al. May 2006 B2
7043287 Khalil et al. May 2006 B1
7054674 Cane et al. May 2006 B2
7088234 Naito et al. Aug 2006 B2
7107088 Aceti Sep 2006 B2
7113815 O'Neil et al. Sep 2006 B2
7117032 Childre et al. Oct 2006 B2
7163512 Childre et al. Jan 2007 B1
7175601 Verjus et al. Feb 2007 B2
7209775 Bae et al. Apr 2007 B2
7217224 Thomas May 2007 B2
7252639 Kimura et al. Aug 2007 B2
7263396 Chen et al. Aug 2007 B2
7289837 Mannheimer et al. Oct 2007 B2
7336982 Yoo et al. Feb 2008 B2
7341559 Schultz et al. Mar 2008 B2
7376451 Mahony et al. May 2008 B2
7470234 Elhag et al. Dec 2008 B1
7483730 Diab et al. Jan 2009 B2
7486988 Goodall et al. Feb 2009 B2
7507207 Sakai et al. Mar 2009 B2
7519327 White Apr 2009 B2
7526327 Blondeau et al. Apr 2009 B2
7583994 Scholz Sep 2009 B2
7620450 Kim et al. Nov 2009 B2
7625285 Breving Dec 2009 B2
7652569 Kiff et al. Jan 2010 B2
7689437 Teller et al. Mar 2010 B1
7695440 Kondo Apr 2010 B2
7725147 Li et al. May 2010 B2
7756559 Abreu Jul 2010 B2
7843325 Otto Nov 2010 B2
7894869 Hoarau Feb 2011 B2
7914468 Shalon et al. Mar 2011 B2
7991448 Edgar et al. Aug 2011 B2
7998079 Nagai et al. Aug 2011 B2
8050728 Al-Ali et al. Nov 2011 B2
8055319 Oh et al. Nov 2011 B2
8055330 Egozi Nov 2011 B2
8059924 Letant et al. Nov 2011 B1
8130105 Al-Ali et al. Mar 2012 B2
8137270 Keenan et al. Mar 2012 B2
8157730 LeBoeuf et al. Apr 2012 B2
8172459 Abreu May 2012 B2
8175670 Baker, Jr. et al. May 2012 B2
8204730 Liu et al. Jun 2012 B2
8204786 LeBoeuf et al. Jun 2012 B2
8233955 Al-Ali et al. Jul 2012 B2
8251903 LeBoeuf et al. Aug 2012 B2
8255027 Al-Ali et al. Aug 2012 B2
8255029 Addison et al. Aug 2012 B2
8303512 Kosuda et al. Nov 2012 B2
8320982 LeBoeuf et al. Nov 2012 B2
8323982 LeBoeuf et al. Dec 2012 B2
8328420 Abreu Dec 2012 B2
8416959 Lott et al. Apr 2013 B2
8491492 Shinar et al. Jul 2013 B2
8504679 Spire et al. Aug 2013 B2
8506524 Graskov et al. Aug 2013 B2
8512242 LeBoeuf et al. Aug 2013 B2
8647270 LeBoeuf et al. Feb 2014 B2
8652040 LeBoeuf Feb 2014 B2
8652409 LeBoeuf et al. Feb 2014 B2
8679008 Hughes et al. Mar 2014 B2
8700111 LeBoeuf Apr 2014 B2
8702607 LeBoeuf et al. Apr 2014 B2
8730048 Shen et al. May 2014 B2
8788002 LeBoeuf et al. Jul 2014 B2
8886269 LeBoeuf et al. Nov 2014 B2
8888701 LeBoeuf et al. Nov 2014 B2
8923941 LeBoeuf et al. Dec 2014 B2
8929965 LeBoeuf et al. Jan 2015 B2
8929966 LeBoeuf et al. Jan 2015 B2
8934952 LeBoeuf et al. Jan 2015 B2
8942776 LeBoeuf et al. Jan 2015 B2
8961415 LeBoeuf et al. Feb 2015 B2
9005129 Venkatraman Apr 2015 B2
9044180 LeBoeuf Jun 2015 B2
9538921 LeBoeuf Jan 2017 B2
9750462 LeBoeuf Sep 2017 B2
9814426 Connor Nov 2017 B2
9949048 Isberg Apr 2018 B2
10130277 Connor Nov 2018 B2
10169561 Razouane Jan 2019 B2
10292601 Perkins May 2019 B2
10297911 Hirsch May 2019 B2
20010049471 Suzuki et al. Dec 2001 A1
20020035340 Fraden et al. Mar 2002 A1
20020143242 Nemirovski Oct 2002 A1
20020156386 Dardik et al. Oct 2002 A1
20020156654 Roe et al. Oct 2002 A1
20020186137 Skardon Dec 2002 A1
20020188210 Aizawa Dec 2002 A1
20020194002 Petrushin Dec 2002 A1
20030002705 Boesen Jan 2003 A1
20030007631 Bolognesi et al. Jan 2003 A1
20030045785 Diab et al. Mar 2003 A1
20030050563 Suribhotla et al. Mar 2003 A1
20030064712 Gaston et al. Apr 2003 A1
20030065257 Mault et al. Apr 2003 A1
20030083583 Kovtun et al. May 2003 A1
20030109030 Uchida et al. Jun 2003 A1
20030181795 Suzuki et al. Sep 2003 A1
20030212336 Lee et al. Nov 2003 A1
20030220584 Honeyager et al. Nov 2003 A1
20030222268 Yocom et al. Dec 2003 A1
20040004547 Appelt et al. Jan 2004 A1
20040011949 Bluemcke et al. Jan 2004 A1
20040022700 Kim et al. Feb 2004 A1
20040030581 Leven Feb 2004 A1
20040034289 Teller et al. Feb 2004 A1
20040034293 Kimball Feb 2004 A1
20040054291 Schulz et al. Mar 2004 A1
20040075677 Loyall et al. Apr 2004 A1
20040077934 Massad Apr 2004 A1
20040082842 Lumba et al. Apr 2004 A1
20040103146 Park May 2004 A1
20040117204 Mazar et al. Jun 2004 A1
20040120844 Tribelsky et al. Jun 2004 A1
20040122294 Hatlestad et al. Jun 2004 A1
20040122702 Sabol et al. Jun 2004 A1
20040133123 Leonhardt et al. Jul 2004 A1
20040135571 Uutela et al. Jul 2004 A1
20040138578 Pineda et al. Jul 2004 A1
20040186390 Ross et al. Sep 2004 A1
20040219056 Tribelsky et al. Nov 2004 A1
20040220488 Vyshedskiy et al. Nov 2004 A1
20040225207 Bae et al. Nov 2004 A1
20040228494 Smith Nov 2004 A1
20040242976 Abreu Dec 2004 A1
20050004458 Kanayama et al. Jan 2005 A1
20050027216 Guillemaud et al. Feb 2005 A1
20050030540 Thornton Feb 2005 A1
20050033200 Soehren et al. Feb 2005 A1
20050038349 Choi et al. Feb 2005 A1
20050043600 Diab et al. Feb 2005 A1
20050043630 Buchert et al. Feb 2005 A1
20050058456 Yoo Mar 2005 A1
20050059870 Aceti Mar 2005 A1
20050070809 Acres Mar 2005 A1
20050084666 Pong et al. Apr 2005 A1
20050101845 Nihtila May 2005 A1
20050101872 Sattler et al. May 2005 A1
20050113167 Buchner et al. May 2005 A1
20050113656 Chance May 2005 A1
20050113703 Farringdon et al. May 2005 A1
20050116820 Goldreich Jun 2005 A1
20050119833 Nanikashvili Jun 2005 A1
20050148883 Boesen Jul 2005 A1
20050154264 Lecompte et al. Jul 2005 A1
20050177034 Beaumont Aug 2005 A1
20050187448 Petersen et al. Aug 2005 A1
20050187453 Petersen et al. Aug 2005 A1
20050192515 Givens et al. Sep 2005 A1
20050196009 Boesen Sep 2005 A1
20050203349 Nanikashvili Sep 2005 A1
20050203357 Debreczeny et al. Sep 2005 A1
20050209516 Fraden Sep 2005 A1
20050222487 Miller et al. Oct 2005 A1
20050222903 Buchheit et al. Oct 2005 A1
20050228244 Banet Oct 2005 A1
20050228299 Banet Oct 2005 A1
20050240087 Keenan et al. Oct 2005 A1
20050258816 Zen et al. Nov 2005 A1
20050259811 Kimm et al. Nov 2005 A1
20060009685 Finarov et al. Jan 2006 A1
20060012567 Sicklinger Jan 2006 A1
20060063993 Yu et al. Mar 2006 A1
20060064037 Shalon et al. Mar 2006 A1
20060084878 Banet et al. Apr 2006 A1
20060084879 Nazarian et al. Apr 2006 A1
20060122520 Banet et al. Jun 2006 A1
20060123885 Yates et al. Jun 2006 A1
20060140425 Berg et al. Jun 2006 A1
20060142665 Garay et al. Jun 2006 A1
20060202816 Crump et al. Sep 2006 A1
20060205083 Zhao Sep 2006 A1
20060210058 Kock et al. Sep 2006 A1
20060211922 Al-Ali et al. Sep 2006 A1
20060211924 Dalke et al. Sep 2006 A1
20060217598 Miyajima et al. Sep 2006 A1
20060224059 Swedlow et al. Oct 2006 A1
20060240558 Zhao Oct 2006 A1
20060246342 MacPhee Nov 2006 A1
20060251277 Cho Nov 2006 A1
20060251334 Oba et al. Nov 2006 A1
20060252999 Devaul et al. Nov 2006 A1
20060264730 Stivoric et al. Nov 2006 A1
20060292533 Selod Dec 2006 A1
20060293921 McCarthy et al. Dec 2006 A1
20070004449 Sham Jan 2007 A1
20070004969 Kong et al. Jan 2007 A1
20070015992 Filkins et al. Jan 2007 A1
20070021206 Sunnen Jan 2007 A1
20070027367 Oliver et al. Feb 2007 A1
20070027399 Chou Feb 2007 A1
20070036383 Romero Feb 2007 A1
20070050215 Kil et al. Mar 2007 A1
20070060800 Drinan et al. Mar 2007 A1
20070060819 Altshuler et al. Mar 2007 A1
20070063850 Devaul et al. Mar 2007 A1
20070082789 Nissila et al. Apr 2007 A1
20070083092 Rippo et al. Apr 2007 A1
20070083095 Rippo et al. Apr 2007 A1
20070088221 Stahmann Apr 2007 A1
20070093702 Yu et al. Apr 2007 A1
20070106167 Kinast May 2007 A1
20070112273 Rogers May 2007 A1
20070112598 Heckerman et al. May 2007 A1
20070116314 Grilliot et al. May 2007 A1
20070118043 Oliver et al. May 2007 A1
20070165872 Bridger et al. Jul 2007 A1
20070167850 Russell et al. Jul 2007 A1
20070191718 Nakamura Aug 2007 A1
20070197878 Shklarski Aug 2007 A1
20070197881 Wolf et al. Aug 2007 A1
20070213020 Novac Sep 2007 A1
20070230714 Armstrong Oct 2007 A1
20070233403 Alwan et al. Oct 2007 A1
20070265097 Havukainen Nov 2007 A1
20070270667 Coppi et al. Nov 2007 A1
20070270671 Gal Nov 2007 A1
20070293781 Sims et al. Dec 2007 A1
20070299330 Couronne et al. Dec 2007 A1
20080004536 Baxi et al. Jan 2008 A1
20080015424 Bernreuter Jan 2008 A1
20080039731 McCombie et al. Feb 2008 A1
20080076972 Dorogusker et al. Mar 2008 A1
20080081963 Naghavi et al. Apr 2008 A1
20080086533 Neuhauser et al. Apr 2008 A1
20080096726 Riley et al. Apr 2008 A1
20080114220 Banet et al. May 2008 A1
20080132798 Hong et al. Jun 2008 A1
20080141301 Azzaro et al. Jun 2008 A1
20080146890 LeBoeuf Jun 2008 A1
20080146892 LeBoeuf Jun 2008 A1
20080154098 Morris et al. Jun 2008 A1
20080154105 Lemay Jun 2008 A1
20080165017 Schwartz Jul 2008 A1
20080170600 Sattler et al. Jul 2008 A1
20080171945 Dotter Jul 2008 A1
20080177162 Bae et al. Jul 2008 A1
20080200774 Luo Aug 2008 A1
20080203144 Kim Aug 2008 A1
20080221461 Zhou et al. Sep 2008 A1
20080249594 Dietrich Oct 2008 A1
20080287752 Stroetz et al. Nov 2008 A1
20090005662 Petersen et al. Jan 2009 A1
20090006457 Stivoric et al. Jan 2009 A1
20090010461 Klinghult et al. Jan 2009 A1
20090030350 Yang et al. Jan 2009 A1
20090054751 Babashan et al. Feb 2009 A1
20090054752 Jonnalagadda et al. Feb 2009 A1
20090069645 Nielsen et al. Mar 2009 A1
20090082994 Schuler et al. Mar 2009 A1
20090088611 Buschmann Apr 2009 A1
20090093687 Telfort et al. Apr 2009 A1
20090105548 Bart Apr 2009 A1
20090105556 Fricke et al. Apr 2009 A1
20090131761 Moroney, III et al. May 2009 A1
20090131764 Lee et al. May 2009 A1
20090175456 Johnson Jul 2009 A1
20090177097 Ma et al. Jul 2009 A1
20090214060 Chuang et al. Aug 2009 A1
20090221888 Wijesiriwardana Sep 2009 A1
20090227853 Wijesiriwardana Sep 2009 A1
20090240125 Such et al. Sep 2009 A1
20090253992 Van Der Loo Oct 2009 A1
20090253996 Lee et al. Oct 2009 A1
20090264711 Schuler et al. Oct 2009 A1
20090270698 Shioi et al. Oct 2009 A1
20090287067 Dorogusker et al. Nov 2009 A1
20090299215 Zhang Dec 2009 A1
20100004517 Bryenton et al. Jan 2010 A1
20100022861 Cinbis et al. Jan 2010 A1
20100045663 Chen et al. Feb 2010 A1
20100100013 Hu et al. Apr 2010 A1
20100113948 Yang et al. May 2010 A1
20100168531 Shaltis et al. Jul 2010 A1
20100172522 Mooring et al. Jul 2010 A1
20100179389 Moroney et al. Jul 2010 A1
20100185105 Baldinger Jul 2010 A1
20100217099 LeBoeuf Aug 2010 A1
20100217100 LeBoeuf Aug 2010 A1
20100217103 Abdul-Hafiz et al. Aug 2010 A1
20100222655 Starr et al. Sep 2010 A1
20100228315 Nielsen Sep 2010 A1
20100234714 Mercier et al. Sep 2010 A1
20100268056 Picard et al. Oct 2010 A1
20100274100 Behar et al. Oct 2010 A1
20100274109 Hu et al. Oct 2010 A1
20100292589 Goodman Nov 2010 A1
20100298653 McCombie et al. Nov 2010 A1
20110028810 Van Slyke et al. Feb 2011 A1
20110028813 Watson et al. Feb 2011 A1
20110081037 Oh et al. Apr 2011 A1
20110098112 LeBoeuf Apr 2011 A1
20110105869 Wilson et al. May 2011 A1
20110112382 Li et al. May 2011 A1
20110130638 Raridan, Jr. Jun 2011 A1
20110142371 King et al. Jun 2011 A1
20110288379 Wu Nov 2011 A1
20120030547 Raptis et al. Feb 2012 A1
20120095303 He Apr 2012 A1
20120150052 Buchheim et al. Jun 2012 A1
20120156933 Kreger et al. Jun 2012 A1
20120179011 Moon et al. Jul 2012 A1
20120203081 LeBoeuf et al. Aug 2012 A1
20120226111 LeBoeuf et al. Sep 2012 A1
20120226112 LeBoeuf et al. Sep 2012 A1
20120277548 Burton Nov 2012 A1
20120283577 LeBoeuf et al. Nov 2012 A1
20120289162 Hosoi Nov 2012 A1
20120296184 LeBoeuf et al. Nov 2012 A1
20130053661 Alberth et al. Feb 2013 A1
20130072765 Kahn et al. Mar 2013 A1
20130131519 LeBoeuf et al. May 2013 A1
20130245387 Patel Sep 2013 A1
20130253338 Kang et al. Sep 2013 A1
20130336495 Burgett et al. Dec 2013 A1
20140012105 LeBoeuf et al. Jan 2014 A1
20140051940 Messerschmidt Feb 2014 A1
20140051948 LeBoeuf et al. Feb 2014 A1
20140052567 Bhardwaj et al. Feb 2014 A1
20140058220 LeBoeuf et al. Feb 2014 A1
20140073486 Ahmed et al. Mar 2014 A1
20140088433 Shan Mar 2014 A1
20140094663 LeBoeuf et al. Apr 2014 A1
20140100432 Golda et al. Apr 2014 A1
20140114147 Romesburg et al. Apr 2014 A1
20140127996 Park et al. May 2014 A1
20140128690 LeBoeuf et al. May 2014 A1
20140135596 LeBoeuf et al. May 2014 A1
20140140567 LeBoeuf et al. May 2014 A1
20140180039 LeBoeuf et al. Jun 2014 A1
20140211959 Boyajian et al. Jul 2014 A1
20140219467 Kurtz Aug 2014 A1
20140235967 LeBoeuf et al. Aug 2014 A1
20140235968 LeBoeuf et al. Aug 2014 A1
20140236531 Carter Aug 2014 A1
20140243617 LeBoeuf et al. Aug 2014 A1
20140243620 LeBoeuf et al. Aug 2014 A1
20140275852 Hong et al. Sep 2014 A1
20140275855 LeBoeuf et al. Sep 2014 A1
20140287833 LeBoeuf et al. Sep 2014 A1
20140288396 LeBoeuf et al. Sep 2014 A1
20140288436 Venkatraman et al. Sep 2014 A1
20140323829 LeBoeuf et al. Oct 2014 A1
20140323830 LeBoeuf et al. Oct 2014 A1
20140323880 Ahmed et al. Oct 2014 A1
20140378844 Fei Dec 2014 A1
20150011898 Romesburg Jan 2015 A1
20150018636 Romesburg Jan 2015 A1
20150031967 LeBoeuf et al. Jan 2015 A1
20150032009 LeBoeuf et al. Jan 2015 A1
20150057967 Albinali Feb 2015 A1
20150190085 Nathan et al. Jul 2015 A1
20150250396 Ahmed et al. Sep 2015 A1
20150265217 Penders et al. Sep 2015 A1
20150289820 Miller et al. Oct 2015 A1
20150342481 Liu et al. Dec 2015 A1
20150366509 Romesburg Dec 2015 A1
20160022220 Lee et al. Jan 2016 A1
20160029964 LeBoeuf et al. Feb 2016 A1
20160094899 Aumer et al. Mar 2016 A1
20160287108 Wei et al. Oct 2016 A1
20160324478 Goldstein Nov 2016 A1
20170034615 Mankodi et al. Feb 2017 A1
20170112671 Goldstein Apr 2017 A1
20170295269 Hosoi Oct 2017 A1
20180133507 Malchano May 2018 A1
20190255350 Malchano Aug 2019 A1
20190269936 Malchano Sep 2019 A1
Foreign Referenced Citations (46)
Number Date Country
101212927 Jul 2008 CN
201438747 Apr 2010 CN
3910749 Oct 1990 DE
1 297 784 Apr 2003 EP
1 480 278 Nov 2004 EP
2 077 091 Jul 2009 EP
2 182 839 Oct 2011 EP
2 408 209 May 2005 GB
2 411 719 Sep 2005 GB
7-241279 Sep 1995 JP
9-253062 Sep 1997 JP
9-299342 Nov 1997 JP
2000-116611 Apr 2000 JP
2001-025462 Jan 2001 JP
2003-159221 Jun 2003 JP
2004-513750 May 2004 JP
2004-283523 Oct 2004 JP
2007-044203 Feb 2007 JP
2007-185348 Jul 2007 JP
2008-136556 Jun 2008 JP
2008-279061 Nov 2008 JP
2009-153664 Jul 2009 JP
2010-526646 Aug 2010 JP
2014-068733 Apr 2014 JP
20-0204510 Nov 2000 KR
WO 0024064 Apr 2000 WO
WO 00047108 Aug 2000 WO
WO 0108552 Feb 2001 WO
WO 2002017782 Mar 2002 WO
WO 2005010568 Feb 2005 WO
WO 2005020121 Mar 2005 WO
WO 2005110238 Nov 2005 WO
WO 2006009830 Jan 2006 WO
WO 2006067690 Jun 2006 WO
WO 2007012931 Feb 2007 WO
WO 2007023426 Mar 2007 WO
WO 2007038432 Apr 2007 WO
WO 2007053146 May 2007 WO
WO 2008141306 Nov 2008 WO
WO 2011127063 Oct 2011 WO
WO 2013019494 Feb 2013 WO
WO 2013038296 Mar 2013 WO
WO 2013109389 Jul 2013 WO
WO 2013109390 Jul 2013 WO
WO 2014092932 Jun 2014 WO
WO 2015128226 Sep 2015 WO
Non-Patent Literature Citations (109)
Entry
(google search results on printed boards) : https://www.google.com/search?q=circuit+board&rlz=1C1GCEA_enUS793US794&sxsrf=ACYBGNSRQsAX2MoHmxzdvAo4srZ4c-2Ndg:1573923221961&source=Inms&tbm=isch&sa=X&ved=2ahUKEwjHurH0mO_IAhWvwVkKHaQMCeEQ_AUoAXoECBYQAw&biw=1920&bih=1095.
-https://www.google.com/search?q=pcb+circuit+board&rlz=1C1GCEA_enUS793US794&sxsrf=ACYBGNSxoNANly5dYh-wQC47-sEBGOITtQ:1580404705297&source=Inms&tbm=isch&sa=X&ved=2ahUKEwiQ1b2o6qvnAhXbl3lEHdhuDKUQ_AUoAnoECA4QBA&biw=1920&bih=1097 , https://www.google.com/search?q=pcb+circuit+board+resin&tbm=isch&ved=2ahUKEwiDqNeq6qv.
https://www.seeedstudio.com/blog/2017/07/23/why-are-printed-circuit-boards-are-usually-green-in-colour/.
International Search Report and Written Opinion of the International Searching Authority, PCT/US2015/041562, dated Oct. 28, 2015, 20 pages.
“U.S. Army Fitness Training Handbook” by the Department of the Army, 2003, The Lyons Press. p. 17.
“Warfighter Physiological and Environmental Monitoring: A Study for the U.S. Army Research Institute in Environmental Medicine and the Soldier Systems Center”, Massachusetts Institute of Technology Lincoln Laboratory, Final Report, Nov. 1, 2004, prepared for the U.S. Army under Air Force Contract F19628-00-C-0002; approved for public release.
Anpo et al. “Photocatalytic Reduction of Co2 With H2O on Titanium Oxides Anchored within Micropores of Zeolites: Effects of the Structure of the Active Sites and the Addition of Pt” J. Phys. Chem. , 101:2632-2636 (1997).
Asada et al, “Mobile Monitoring with Wearable Photoplethysmographic Biosensors,” IEEE Engineering in Medicine and Biology Magazine, May/Jun. 2003, pp. 28-40.
Bârsan et al. “Understanding the fundamental principles of metal oxide based gas sensors; the example of CO sensing with SnO2 sensors in the presence of humidity” Journal of Physics: Condensed Matter 15:R813-R839 (2003).
Bifulco et al., “Bluetooth Portable Device for Continuous ECG and Patient Motion Monitoring During Daily Life,” Medicon 2007, IFMBE Proceedings 16, 2007, pp. 369-372.
Bott “Electrochemistry of Semiconductors” Current Separations 17(3):87-91 (1998).
Brodersen et al., “In-Ear Acquisition of Vital Signs Discloses New Chances for Preventive Continuous Cardiovascular Monitoring,” 4th International Workshop on Wearable and Implantable Body Sensor Networks (BSN 2007), vol. 13 of the series IFMBE Proceedings, pp. 189-194.
Celka et al., “Motion Resistant Earphone Located Infrared based Heart Rate Measurement Device,” Proceedings of the Second IASTED International Conference on Biomedical Engineering, Feb. 16-18, 2004, Innsbruck, Austria, pp. 582-585.
Colligan, M. J. et al. in “The psychological effects of indoor air pollution”, Bulletin of the New York Academy of Medicine, vol. 57, No. 10, Dec. 1981, p. 1014-1026.
Communication pursuant to Article 94(3) EPC, European Application No. 12 739 502.8, dated Nov. 30, 2016, 6 pages.
Communication Pursuant to Article 94(3) EPC, EP 12 739 502.8, dated Jul. 19, 2016, 7 pages.
Communication pursuant to Article 94(3) EPC, EP 12 820 308.0, dated Feb. 3, 2016, 5 pages.
Communication pursuant to Article 94(3) EPC, EP 13 863 449.8, dated Nov. 5, 2015, 7 pages.
Communication pursuant to Article 94(3) EPC, EP 14 743 615.8, dated Dec. 23, 2015, 7 pages.
Communication Pursuant to Article 94(3) EPC, EP 14 743 615.8, dated Jul. 19, 2016, 7 pages.
Communication pursuant to Article 94(3) EPC, EP 14 743 839.4, dated Dec. 23, 2015, 6 pages.
Communication Pursuant to Article 94(3) EPC, EP 14 743 839.4, dated Jul. 20, 2016, 5 pages.
Comtois et al., “A Wearable Wireless Reflectance Pulse Oximeter for Remote Triage Applications,” 2006 IEEE, pp. 53-54.
Comtois, Gary, W., “Implementation of Accelerometer-Based Adaptive Noise Cancellation in a Wireless Wearable Pulse Oximeter Platform for Remote Physiological Monitoring and Triage,” Thesis, Worcester Polytechnic Institute, Aug. 31, 2007, 149 pages.
De Paula Santos, U. et al., in “Effects of air pollution on blood pressure and heart rate variability: a panel study of vehicular traffic controllers in the city of Sao Paulo, Brazil”, European Heart Journal (2005) 26, 193-200.
Duun et al., “A Novel Ring Shaped Photodiode for Reflectance Pulse Oximetry in Wireless Applications,” IEEE Sensors 2007 Conference, pp. 596-599.
Ebert, T et al., “Influence of Hydration Status on Thermoregulation and Cycling Hill Climbing,” Med. Sci. Sport Exerc. vol. 39, No. 2, pp. 323-329, 2007.
Edmison et al., “E-Textile Based Automatic Activity Diary for Medical Annotation and Analysis,” Proc. BSN 2006 Int. Workshop Wearable Implantable Body Sensor Netw. (2006), pp. 131-145, Apr. 3-5, 2006.
European Search Report corresponding to European Application No. 07862660.3 dated Apr. 25, 2012; 7 pages.
European Search Report, EP Application No. 13863449.8, dated Oct. 19, 2015, 3 pages.
European Search Report, EP Application No. 14743615.8, dated Oct. 12, 2015, 3 pages.
European Search Report, EP Application No. 14743839.4, dated Oct. 12, 2015, 3 pages.
Extended European Search Report, European Application No. 16183137.5, dated Jan. 12, 2017, 12 pages.
Extended European Search Report, European Application No. 16184560.7, dated Dec. 20, 2016, 9 pages.
Extended European Search Report, EP Application No. 16164775.5, dated Sep. 13, 2016, 7 pages.
Falkner et al., “Cardiovascular response to mental stress in normal adolescents with hypertensive parents. Hemodynamics and mental stress in adolescents,” Hypertension 1979, 1:23-30.
Fitrainer “The Only Trainer You Need”; http://itami.com; Downloaded Feb. 26, 2010; © 2008 FiTriainer™; 2 pages.
Fleming et al., “A Comparison of Signal Processing Techniques for the Extraction of Breathing Rate from the Photopethysmorgram,” World Academy of Science, Engineering and Technology, vol. 30, Oct. 2007, pp. 276-280.
Geladas et al., “Effect of cold air inhalation on core temperature in exercising subjects under stress,” The American Physiological Society, pp. 2381-2387, 1988.
Geun et al., “Measurement Site and Applied Pressure Consideration in Wrist Photoplethysmography,” The 23rd International Technical Conference on Circuits/Systems, Computers and Communications, 2008, pp. 1129-1132.
Gibbs et al., “Active motion artifact cancellation for wearable health monitoring sensors using collocated MEMS accelerometers,” Smart Structures and Materials, 2005: Sensors and Smart Structures Technologies for Civil, Mechanical, and Aerospace Systems, Proc. of SPIE, vol. 5765, pp. 811-819.
Gibbs et al., “Reducing Motion Artifact in Wearable Bio-Sensors Using MEMS Accelerometers for Active Noise Cancellation,” 2005 American Control Conference, Jun. 8-10, 2005, Portland, OR, USA, pp. 1581-1586.
Gold, D.R. et al. in “Ambient Pollution and Heart Rate Variability”, Circulation 2000, 101:1267-1273.
Haahr et al., “A Wearable “Electronic Patch” for Wireless Continuous Monitoring of Chronically Diseased Patients,” Proceedings of the 5th International Workshop on Wearable and Implantable Body Sensor Networks, in conjunction with The 5th International Summer School and Symposium on Medical Devices and Biosensors, The Chinese University of Hong Kong, HKSAR, China, Jun. 1-3, 2008, pp. 66-70.
Han et al., “Artifacts in wearable photoplethysmographs during daily life motions and their reduction with least mean square based active noise cancellation method,” Computers in Biology and Medicine, 42, 2012, pp. 387-393.
International Preliminary Report on Patentability, PCT/US2014/012940, dated Jun. 17, 2015, 23 pages.
International Search Report and Written Opinion of the International Searching Authority, corresponding to International Patent Application No. PCT/US2014/012940, dated Oct. 16, 2014, 3 pages.
International Search Report and Written Opinion of the International Searching Authority, corresponding to PCT/US2012/0948079, dated Oct. 9, 2012.
International Search Report and Written Opinion of the International Searching Authority, corresponding to PCT/US2007/025114, dated May 13, 2008.
International Search Report Corresponding to International Application No. PCT/US2012/022634, dated Aug. 22, 2012, 9 pages.
International Search Report corresponding to International Patent Application No. PCT/US2014/012909, dated May 13, 2014, 3 pages.
International Search Report corresponding to International Patent Application No. PCT/US2012/046446, dated Jan. 14, 2013, 3 pages.
Jiang, Honghui, “Motion-Artifact Resistant Design of Photoplethysmograph Ring Sensor for Driver Monitoring,” Thesis, Massachusetts Institute of Technology, Feb. 2004, 62 pages.
Kuzmina et al., “Compact multi-functional skin spectrometry set-up,” Advanced Optical Materials, Technologies, and Devices, Proc. of SPIE, vol. 6596, 2007, pp. 65960T-1 to 65960T-6.
Lee et al., “Respiratory Rate Detection Algorithms by Photoplethysmography Signal Processing,” 30th Annual International IEEE EMBS Conference, Vancouver, British Columbia, Canada, Aug. 20-24, 2008, pp. 1140-1143.
Lindberg et al., “Monitoring of respiratory and heart rates using a fibre-optic sensor,” Med Biol Eng Comput, Sep. 1992, vol. 30, No. 5, pp. 533-537.
Luprano, Jean, “Sensors and Parameter Extraction by Wearable Systems: Present Situation and Future,” pHealth 2008, May 21, 2008, 29 pages.
Lygouras et al., “Optical-Fiber Finger Photo-Plethysmograph Using Digital Techniques,” IEEE Sensors Journal, vol. 2, No. 1, Feb. 2002, pp. 20-25.
Maguire et al., “The Design and Clinical Use of a Reflective Brachial Photoplethysmograph,” Technical Report NUIM/SS/--/2002/04, Submitted Apr. 2002, Signals and Systems Research Group, National University of Ireland, Maynooth, Co. Kildare, Ireland, 13 pages.
Maomao et al., “Mobile Context-Aware Game for the Next Generation,” 2nd International Conference on Application and Development of Computer Games ADCOG 2003, p. 78-81.
Martins et al. “Zinc oxide as an ozone sensor” Journal of Applied Physics 96(3): 1398-1408 (2004).
Maughan et al., “Exercise, Heat, Hydration and the Brain,” Journal of the American College of Nutrition, vol. 26, No. 5, pp. 604S-612S, 2007.
Maughan, R.J., “Impact of mild dehydration on wellness and on exercise performance,” European Journal of Clinical Nutrition, 57, Suppl. 2, pp. S19-S23, 2003.
Mendelson et al., “Measurement Site and Photodetector Size Considerations in Optimizing Power Consumption of a Wearable Reflectance Pulse Oximeter,” Proceedings of the 25th Annual International Conference of the IEEE EMBS, Cancun, Mexico, Sep. 17-21, 2003, pp. 3016-3019.
Mendelson et al., “Noninvasive Pulse Oximetry Utilizing Skin Reflectance Photoplethysmography,” IEEE Transactions on Biomedical Engineering, vol. 35, No. 10, Oct. 1988, pp. 798-805.
Mostardi, R., et al., “The effect of increased body temperature due to exercise on the heart rate and the maximal aerobic power,” Europ. J. Appl. Physiol, 33, pp. 237-245, 1974.
Nakajima et al., “Monitoring of heart and respiratory rates by photoplethyusmography using a digital filtering technique,” Med. Eng. Phys., vol. 18, No. 5, Jul. 1996, pp. 365-372.
Notification Concerning Transmittal of International Preliminary Report on Patentability, PCT/US2014/012909, dated Jul. 28, 2015.
Notification of Transmittal of International Preliminary Report on Patentability, PCT/US2015/041562, dated Oct. 20, 2016, 14 pages.
Notification of Transmittal of International Preliminary Report on Patentability, PCT/US2015/042636, dated Oct. 20, 2016, 7 pages.
Notification of Transmittal of International Preliminary Reporton Patentability, PCT/US2015/042015, dated Oct. 20, 2016, 10 pages.
Notification of Transmittal of International Preliminary Report on Patentability, PCT/US2015/042035, dated Oct. 20, 2016, 8 pages.
Notification of Transmittal of International Preliminary Report on Patentability, PCT/US2015/046079, dated Oct. 20, 2016, 10 pages.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority, or the Declaration, PCT/US2016/046273, dated Nov. 25, 2016, 24 pages .
Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority, or the Declaration, PCT/US2016/041842, dated Oct. 21, 2016, 5 pages.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority, or the Declaration, PCT/US2016/058098, dated Jan. 10, 2017, 13 pages.
Notification of Transmittal of the International Search Report and Written Opinion of the International Search Authority dated May 26, 2016 by the Korean Intellectual Property Office for corresponding International Application No. PCT/US2016/019126.
Notification of Transmittal of the International Search Report and Written Opinion of the International Search Authority dated May 26, 2016 by the Korean Intellectual Property Office for corresponding International Application No. PCT/US2016/019132.
Notification of Transmittal of the International Search Report and Written Opinion of the International Search Authority dated Jul. 30, 2010 by the Korean Intellectual Property Office for corresponding International Application No. PCT/US2010/021936.
Notification of Transmittal of the International Search Report and Written Opinion of the International Search Authority dated Aug. 26, 2010 by the Korean Intellectual Property Office for corresponding International Application No. PCT/US2010/021629.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Search Authority dated Sep. 16, 2010 by the Korean Intellectual Property Office for corresponding International Application No. PCT/US2010/024922.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Search Authority dated Sep. 27, 2010 by the Korean Intellectual Property Office for corresponding International Application No. PCT/US2010/025216.
Notification of Transmittal of The International Search Report and The Written Opinion of the International Searching Authority, or the Declaration corresponding to International Application No. PCT/US2013/070271; dated Feb. 26, 2014; 13 pages.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority, or the Declaration, PCT/US2015/042636, dated Oct. 29, 2015.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority, or the Declaration, PCT/US2015/042015, dated Oct. 29, 2015.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority, or the Declaration, PCT/US2015/042035, dated Oct. 29, 2015.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority, or the Declaration, PCT/US2015/046079, dated Dec. 29, 2015.
Poh et al., “Motion Tolerant Magnetic Earring Sensor and Wireless Earpiece for Wearable Photoplethysmography,” IEEE Transactions on Information Technology in Biomedicine, vol. 14, No. 3, May 2010, pp. 786-794.
Renevey et al., “Wrist-Located Pulse Detection Using IR Signals, Activity and Nonlinear Artifact Cancellation,” IEEE EMBS, 2001, 4 pages.
Rhee et al., “Artifact-Resistant Power-Efficient Design of Finger-Ring Plethysmographic Sensors,” IEEE Transactions on Biomedical Engineering, vol. 48, No. 7, Jul. 2001, pp. 795-805.
Saladin et al. “Photosynthesis of CH4 at a TiO2 Surface from Gaseous H2 O and CO2” J. Chem. Soc., Chem. Commun. 533-534 (1995).
Shaltis, Phillip Andrew, Analysis and Validation of an Artifact Resistant Design for Oxygen Saturation Measurement Using Photo Plethysmographic Ring Sensors, Thesis, Massachusetts Institute of Technology, Jun. 2004, 103 pages.
Shin et al., “A Novel Headset with a Transmissive PPG Sensor for Heart Rate Measurement,” ICBME 2008, Proceedings 23, 2009, pp. 519-522.
Shorten et al., “Acute effect of environmental temperature during exercise on subsequent energy intake in active men,” Am. J Clin. Nutr. 90, pp. 1215-1221, 2009.
Skubal et al. “Detection and identification of gaseous organics using a TiO2 sensor” Journal of Photochemistry and Photobiology A: Chemistry 148:103-108 (2002).
Skubal et al. “Monitoring the Electrical Response of Photoinduced Organic Oxideation on TiO2 Surfaces” Manuscript submitted Oct. 2000 to SPIE Intl. Symposium on Environment & Industrial Sensing, Boston, MA, Nov. 5-8, 2000, sponsored by SPIE, 10 pp.
Spigulis et al., “Wearable wireless photoplethysmography sensors,” Proc. of SPIE, vol. 6991, 2008, pp. 69912O-1 to 69912O-7.
Takatani et al., “Optical Oximetry Sensors for Whole Blood and Tissue, IEEE Engineering in Medicine and Biology,” Jun./Jul. 1994, pp. 347-357.
Thompson, M.W., “Cardiovascular drift and critical core temperature: factors limiting endurance performance in the heat?” J. Exerc. Sci. Fit, vol. 4, No. 1, pp. 15-24, 2006.
Vogel et al., “A System for Assessing Motion Artifacts in the Signal of a Micro-Optic In-Ear Vital Signs Sensor,” 30th Annual International IEEE EMBS Conference, Vancouver, British Columbia, Canada, Aug. 20-24, 2008.
Vogel et al., “In-Ear Heart Rate Monitoring Using a Micro-Optic Reflective Sensor,” Proceedings of the 29th Annual International Conference of the IEEE EMBS Cite Internationale, Lyon, France, Aug. 23-26, 2007, pp. 1375-1378.
Wang et al., “Multichannel Reflective PPG Earpiece Sensor With Passive Motion Cancellation,” IEEE Transactions on Biomedical Circuits and Systems, vol. 1, No. 4, Dec. 2007, pp. 235-241.
Wang et al., “Reflective Photoplethysmograph Earpiece Sensor for Ubiquitous Heart Rate Monitoring,” 4th International Workshop on Wearable and Implantable Body Sensor Networks, 2007, vol. 13 of the series IFMBE Proceedings, pp. 179-183.
Wei et al. “A New Wristband Wearable Sensor Using Adaptive Reduction Filter to Reduce Motion Artifact,” Proceedings of the 5th International Conference on Information Technology and Application in Biomedicine, in conjunction with The 2nd International Symposium & Summer School on Biomedical and Health Engineering, Shenzhen, China, May 30-31, 2008, pp. 278-281.
Wood et al., “Active Motion Artifact Reduction for Wearable Sensors Using Laguerre Expansion and Signal Separation,” Proceedings of the 2005 IEEE Engineering in Medicine and Biology, 27th Annual Conference, Shanghai, China, Sep. 1-4, 2005, pp. 3571-3574.
Wood, Levi Benjamin, “Motion Artifact Reduction for Wearable Photoplethysmogram Sensors Using Micro Accelerometers and Laguerre Series Adaptive Filters,” Thesis, Massachusetts Institute of Technology, Jun. 2008, 74 pages.
Zhang et al. “Development of Chemical Oxygen Demand On-Line Monitoring System Based on a Photoelectrochemical Degradation Principle” Environ. Sci. Technol., 40(7):2363-2368 (2006).
Extended European Search Report corresponding to European Application No. 15830336.2 dated Jun. 7, 2017 (8 pages).
“Communication Pursuant to Article 94(3) EPC”, EP Application No. 17150916.9, dated Oct. 2, 2020, 6 pp.
Related Publications (1)
Number Date Country
20180302709 A1 Oct 2018 US
Provisional Applications (1)
Number Date Country
62033922 Aug 2014 US
Continuations (1)
Number Date Country
Parent 15324139 US
Child 16011985 US