Claims
- 1. A compound having the following physicochemical properties:
- 1) appearance: yellow powder;
- 2) molecular weight (FABMS, (M+H).sup.30)=1127;
- 3) molecular formula: C.sub.59 H.sub.86 N.sub.2 O.sub.19 ;
- 4) melting point: turns brown at 135.degree. C.;
- 5) UV spectrum: as shown in FIG. 1;
- 6) solubility in solvents: insoluble in water, diethyl ether, hexane and chloroform; slightly soluble in methanol, ethanol and n-butanol; soluble in dimethyl sulfoxide and N,N-dimethylformamide;
- 7) color reaction: phenol-sulfuric acid: positive, ferric chloride: negative, ninhydrin: positive, concentrated sulfuric acid: positive, iodine: positive;
- 8) .sup.1 H--NMR spectrum: as shown in FIG. 2;
- 9) .sup.13 D--NMR spectrum: as shown in FIG. 3;
- 10) specific rotation: [.alpha.].sub.D.sup.20 +296.degree. (C=0.1% DMSO);
- 11) IR spectrum: as shown in FIG. 4.
- 2. A method for treating a patient in need of a treatment of bacteriosis, and said treatment comprising administering an amount effective to treat bacteriosis in said patient of a compound having the following physicochemical properties:
- 1) appearance: yellow powder;
- 2) molecular weight (FABMS, (M+H).sup.30)=1127;
- 3) molecular formula: C.sub.59 H.sub.86 N.sub.2 O.sub.19 ;
- 4) melting point: product turns brown at 135.degree. C.;
- 5) UV spectrum: as shown in FIG. 1;
- 6) solubility: insoluble in water, diethyl ether, hexane and chloroform; slightly soluble in methanol, ethanol and n-butanol; and soluble in dimethyl sulfoxide and N,N-dimethylformamide;
- 7) color reaction: phenol-sulfuric acid: positive, ferric chloride: negative, ninhydrin: positive, concentrated sulfuric acid: positive, iodine: positive;
- 8) .sup.1 H--NMR spectrum: as shown in FIG. 2;
- 9) .sup.13 C--NMR spectrum: as shown in FIG. 3;
- 10) specific rotation: [.alpha.].sub.D.sup.20 +296.degree. (C=0.1% DMSO);
- 11) IR spectrum: as shown in FIG. 4
- 3. A method for producing a compound having the following physicochemical properties:
- 1) appearance: yellow powder;
- 2) molecular weight (FABMS, (M+H).sup.30)=1127;
- 3) molecular formula: C.sub.59 H.sub.86 N.sub.2 O.sub.19 ;
- 4) melting point: product turns brown at 135.degree. C.;
- 5) UV spectrum: as shown in FIG. 1;
- 6) solubility: insoluble in water, diethyl ether, hexane and chloroform; slightly soluble in methanol, ethanol and n-butanol; and soluble in dimethyl sulfoxide and N,N-dimethylformamide;
- 7) color reaction: phenol-sulfuric acid: positive, ferric chloride: negative, ninyydrin: positive, concentrated sulfuric acid: positive, iodine: positive;
- 8) .sup.1 H--NMR spectrum: as shown in FIG. 2;
- 9) .sup.13 C--NMR spectrum: as shown in FIG. 3;
- 10) specific rotation: [.alpha.].sub.D.sup.20 +296.degree. (C=0.1% DMSO);
- 11) IR spectrum: as shown in fIG. 4, said process comprising:
- methyl esterifying heptaene V-28-3 by adding to a methyl alcohol suspension of V-28-3, at ice temperature, an amount of a diazomethane solution in tetrahydrofuran, sufficient to produce said compound, mixing for a period of time sufficient to produce said compound at room temperature, and recovering said compound.
- 4. The process of claim 3, wherein said recovering step comprises removing the methyl alcohol and tetrahydrofuran to obtain a dry product, and then isolating said compound from said dry product by chromatography.
Priority Claims (1)
Number |
Date |
Country |
Kind |
62-051570 |
Mar 1987 |
JPX |
|
Parent Case Info
This application is a Continuation-In-Part of application Ser. No. 164,973, filed on Mar. 7, 1988, now abandoned.
Non-Patent Literature Citations (1)
Entry |
Chemical Abstracts 106:137002d (1987). |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
164973 |
Mar 1988 |
|