Claims
- 1. An herbal pharmaceutical compositions comprising:
an extract of Radix Scutellariae (root of scutellaria); an extract of Rhizoma Coptidis (rhizome of coptis); an extract of Radix et Rhizoma Rhei (root and rhizome of rhubarb); and dry powders of Radix Ginseng (root of ginseng) or Radix Panacis Quinquefoli (American ginseng); wherein said extract of said root of scutellaria, said extract of said rhizoma of coptis, and said extract of said root and rhizome of rhubarb are produced by extracting said root of scutellaria, said rhizoma of coptis, said root and rhizome of rhubarb by a solvent which is at least one selected from the group consisting of water and alcohol.
- 2. The herbal pharmaceutical composition according to claim 1, wherein said dry powers of the root of ginseng or American ginseng is replaced with Rhizoma Zingiberis (rhizome of ginger).
- 3. The herbal pharmaceutical composition according to claim 1, wherein said root of scutellaria and said rhizome of coptis are extracted by water.
- 4. The herbal pharmaceutical composition according to claim 1, wherein said root and rhizome of rhubarb is extracted by alcohol or a mixture of alcohol and water.
- 5. The herbal pharmaceutical composition according to claim 4, wherein said root and rhizome of rhubarb is extracted by 95:5 by volume of alcohol and water.
- 6. The herbal pharmaceutical composition according to claim 1, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng are at a weight ratio of about 1-2:1-2:1-2:1-2.
- 7. The herbal pharmaceutical composition according to claim 1, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng or American ginseng are at a weight ratio of about 1:1:1:1.
- 8. The herbal pharmaceutical composition according to claim 2, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said rhizome of ginger are at a weight ratio of about 1-2:1-2:1-2:1-2.
- 9. The herbal pharmaceutical composition according to claim 2, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said rhizome of ginger are at a weight ratio of about 1:1:1:1.
- 10. The herbal pharmaceutical composition according to claim 1, wherein said herbal pharmceutical compositions is used to prevent patients from developing or treat patients with cardiovascular diseases.
- 11. The herbal pharmaceutical composition according to claim 10, wherein said cardiovascular diseases is at least one selected from the group consisting of hypertension, coronary heart disease, cerebrovascular disease, peripheral vascular disease, heart failure, rheumatic heart disease, congestive heart disease, and cardiomyopathies.
- 12. The herbal pharmaceutical composition according to claim 1, wherein said herbal pharmaceutical compositions is used to treat patients with hypertension.
- 13. The herbal pharmaceutical composition according to claim 1, wherein said herbal pharmaceutical compositions inhibits inducible nitric oxide synthase (iNOS).
- 14. The herbal pharmaceutical composition according to claim 1, wherein said herbal pharmaceutical compositions inhibits cyclooxygenase 2 (COX-2) activity.
- 15. The herbal pharmaceutical composition according to claim 1, wherein said herbal pharmaceutical compositions reduces C-reactive protein (CRP) concentration in serum.
- 16. The herbal pharmaceutical composition according to claim 1, wherein said herbal pharmaceutical compositions further comprises a pharmaceutically acceptable excipient and/or carrier.
- 17. The herbal pharmaceutical composition according to claim 1, wherein said herbal pharmaceutical compositions is formulated as one selected from the group consisting of granule, capsule, tablet, powder, and bolus.
- 18. The herbal pharmaceutical composition according to claim 17, wherein said herbal pharmaceutical composition is a tablet.
- 19. A method for preparing the herbal pharmaceutical composition according to claim 1 comprising:
extracting said root of scutellaria with said solvent to form said extract of root of scutellaria; extracting rhizome of coptis with said solvent to form said extract of rhizome of coptis; extracting said root and rhizome of rhubarb with said solvent to form said extract of said root and rhizome of rhubarb; mixing said extracts of said root of scutellaria, said rhizome of coptis, and said root and rhizome of rhubarb to form an herbal extract mixture; condensing said herbal extract mixture to form an herbal paste; grinding said root of ginseng or American ginseng to make dry powders of ginseng or American ginseng; adding said dry powders of ginseng or American ginseng to said herbal paste; and drying said paste to form the herbal pharmaceutical composition.
- 20. The method according to claim 21, wherein said root of ginseng or American ginseng is replaced with Rhizoma Zingiberis (rhizome of ginger).
- 21. The method according to claim 19, wherein said root of scutellaria and said rhizome of coptis are extracted by water.
- 22. The method according to claim 19, wherein said root and rhizome of rhubarb is extracted by alcohol or a mixture of alcohol and water.
- 23. The method according to claim 19, wherein said root and rhizome of rhubarb is extracted by 95% (v/v) of alcohol in water.
- 24. The method according to claim 19, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng or American ginseng are at a weight ratio of about 1-2:1-2:1-2:1-2.
- 25. The method according to claim 19, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng or American ginseng are at a weight ratio of about 1:1:1:1.
- 26. The method according to claim 20, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said rhizome of ginger are at a weight ratio of about 1-2:1-2:1-2:1-2.
- 27. The method according to claim 20, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng or American ginseng are at a weight ratio of about 1:1:1:1.
- 28. A method for preventing patients from developing or treating patients with cardiovascular diseases comprising:
adminstering an effective amount of the herbal pharmaceutical composition according to claim 1 to said patients.
- 29. The method according to claim 30, wherein said herbal pharmaceutical composition is orally administered to patients.
- 30. The method according to claim 31, wherein said cardiovascular diseases is at least one selected from the group consisting of hypertension, coronary heart disease, cerebrovascular disease, peripheral vascular disease, heart failure, rheumatic heart disease, congenital heart disease, and cardiomyopathies.
- 31. A method for treating patients with hypertension and/or ischemia comprising:
adminstering an effective amount of an herbal pharmaceutical composition to said patients; wherein said herbal pharmaceutical composition comprising: an extract of Radix Scutellariae (root of scutellaria); an extract of Rhizoma Coptidis (rhizome of coptis); an extract of Radix et Rhizoma Rhei (root and rhizome of rhubarb); and dry powder of Radix Ginseng (root of ginseng) or Radix Panacis Quinquefolii (American ginseng); wherein said extract of said root of scutellaria, said extract of said rhizoma of coptis, and said extract of said root and rhizome of rhubarb are produced by extracting said root of scutellaria, said rhizoma of coptis, said root and rhizome of rhubarb by a solvent which is at least one selected from the group consisting of water and alcohol.
- 32. A method for inhibiting inducible nitric oxide synthase (iNOS) activity in patients comprising:
adminstering an effective amount of the herbal pharmaceutical composition according to claim 1 to said patients.
- 33. A method for inhibiting cyclooxygenase 2 (COX 2) activity in patients comprising:
adminstering an effective amount of the herbal pharmaceutical composition according to claim 1 to said patients.
- 34. A method for reducing serum CRP concentration in patients comprising:
adminstering an effective amount of the herbal pharmaceutical composition according to claim 1 to said patients.
- 35. An herbal pharmaceutical composition comprising:
dry powders of Radix Scutellariae (root of scutellaria); dry powders of Rhizoma Coptidis (rhizome of coptis); dry powders of Radix et Rhizoma Rhei (root and rhizome of rhubarb); and dry powders of Radix Ginseng (root of ginseng) or Radix Panacis Quinquefolii (American ginseng).
- 36. The herbal pharmaceutical composition according to claim 35, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng or American ginseng are at a weight ratio of about 1-2:1-2:1-2:1-2.
- 37. The herbal pharmaceutical composition according to claim 35, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng or American ginseng are at a weight ratio of about 1:1:1:1.
- 38. The herbal pharmaceutical composition according to claim 35, wherein said root of ginseng or American ginseng is replaced with Rhizoma Zingiberis (rhizome of ginger).
- 39. The herbal pharmaceutical composition according to claim 35, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said rhizome of ginger are at a weight ratio of about 1-2:1-2:1-2:1-2.
- 40. The herbal pharmaceutical composition according to claim 35, wherein said root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said rhizome of ginger are at a weight ratio of about 1:1:1:1.
- 41. A method for preparing the herbal pharmaceutical composition according to claim 35 comprising:
individually cutting and root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng or American ginseng into dry powders; and mixing said individually ground dry powders of root of scutellaria, said rhizome of coptis, said root and rhizome of rhubarb, and said root of ginseng or American ginseng.
- 42. The method according to claim 41, wherein said root of ginseng or American ginseng is replaced with Rhizoma Zingiberis (rhizome of ginger).
- 43. The method according to claim 31, wherein said herbal pharmaceutical composition is orally administered to patients.
- 44. The method according to claim 31, wherein said herbal pharmaceutical composition is used to lower blood pressure or maintain stable blood pressure in said patients.
Priority Claims (1)
Number |
Date |
Country |
Kind |
90131897 |
Dec 2003 |
TW |
|
RELATED APPLICATIONS
[0001] The present invention is a Divisional Application of U.S. patent application Ser. No. 10/164,568, filed on Jun. 10, 2002, which in turn claims the priority on Taiwanese application number 90131897, filed on Dec. 21, 2001, which are herein incorporated by reference.
Divisions (1)
|
Number |
Date |
Country |
Parent |
10164568 |
Jun 2002 |
US |
Child |
10875812 |
Jun 2004 |
US |