TREA

HERBICIDE TRIAZOLYLPYRIDINE KETONES

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Information

  • Patent Application
  • 20130296168
  • Publication Number
    20130296168
  • Date Filed
    May 22, 2013
    11 years ago
  • Date Published
    November 07, 2013
    10 years ago
Information
Abstract
Triazolylpyridine ketones expressed by the following formula (1) and use thereof as herbicides.
Description
BACKGROUND OF THE INVENTION

1. Field of the Invention


This invention relates to novel triazolylpyridine ketones, use thereof as herbicides, manufacturing methods thereof, and novel intermediates thereof.


2. Description of Related Art


It is already known that some kinds of aryl ketones show action as herbicides (For example, WO 97/46530-A, WO 99/03845-A, WO 00/15615-A, and Japanese Patent Application Laid-Open (JP-A) No. 2005-60299).


DISCLOSURE OF INVENTION

However, compounds disclosed in the above publications are not sufficiently satisfactory in the effect and/or safety as herbicides.


SUMMARY

The present inventors zealously studied in order to create novel compounds having higher effects and higher safety as herbicides. As a result, novel triazolylpyridine ketones of the following formula (I), which have excellent herbicide activity and show safety to crops, and which are represented by the following formula (I), have been founded out.




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In the formula, R1 represents alkyl, cycloalkyl, cycloalkyl-alkyl, haloalkyl, alkenyl, alkynyl, aryl, aralkyl, alkoxyalkyl, cycloalkyl-alkoxyalkyl, haloalkoxyalkyl, alkenyloxyalkyl, alkynyloxyalkyl, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl, cycloalkyl-alkylthioalkyl, cycloalkyl-alkylsulfinylalkyl, cycloalkyl-alkylsulfonylalkyl, haloalkylthioalkyl, haloalkylsulfinylalkyl, haloalkylsulfonylalkyl, alkenylthioalkyl, alkenylsulfinylalkyl, alkenylsulfonylalkyl, alkynylthioalkyl, alkynylsulfinylalkyl, alkynylsulfonylalkyl, alkoxyalkoxyalkyl, cycloalkyl-alkoxyalkoxyalkyl, haloalkoxyalkoxyalkyl, alkenyloxyalkoxyalkyl, alkynyloxyalkoxyalkyl, alkylthioalkoxyalkyl, alkylsulfinylalkoxyalkyl, alkylsulfonylalkoxyalkyl, cycloalkyl-alkylthioalkoxyalkyl, cycloalkyl-alkylsulfinylalkoxyalkyl, cycloalkyl-alkylsulfonylalkoxyalkyl, haloalkylthioalkoxyalkyl, haloalkylsulfinylalkoxyalkyl, haloalkylsulfonylalkoxyalkyl, alkenylthioalkoxyalkyl, alkenylsulfinylalkoxyalkyl, alkenylsulfonylalkoxyalkyl, alkynylthioalkoxyalkyl, alkynylsulfinylalkoxyalkyl, alkynylsulfonylalkoxyalkyl, cyclic ether-O-alkyl, cyclic ether-alkoxyalkyl, alkylsulfonylaminoalkoxyalkyl, cycloalkyl-alkylsulfonylaminoalkoxyalkyl, haloalkylsulfonylaminoalkoxyalkyl, alkylthio, alkylsulfinyl, alkylsulfonyl, alkoxy, haloalkoxy, alkoxyalkoxy, or NR2R3, R2 and R3 respectively represent hydrogen or alkyl,


Q represents




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R4 represents hydroxy, halogen, alkylthio, substituted phenylthio, substituted benzylthio, substituted-1-pyrazolyl, substituted-1-imidazolyl, 1,2,4-triazolyl-1-yl, 1H-tetrazol-1-yl or 2H-tetrazol-2-yl,


R5, R6, R7, R8, R9, and R10 respectively represent hydrogen or alkyl,


R5 and R10 together represent ethylene or —CH═CH—,


R7 and R8 together represent carbonyl,


R11 represents alkyl,


R12 represents hydrogen, alkyl, or cycloalkyl,


R13 represents hydrogen, alkyl, alkenyl, alkynyl, aralkyl, alkylsulfonyl, substituted phenylsulfonyl, acyl, or acylalkyl,


R14 represents alkyl or cycloalkyl, and


R15 represents hydrogen, alkoxycarbonyl, or alkylthio.







DETAILED DESCRIPTION OF A PREFERRED EMBODIMENT

Compounds of the above formula (I) of the present invention can be synthesized, for example, by means of either of the following manufacturing method (a), (b), (c), (d), (e), (f), (g), (h), (i), or (j).


Manufacturing Method (a)

In the case that compounds in which Q represents Q1 and R4 represents hydroxyl, or Q represents Q2 and R13 represents hydrogen are manufactured: a method of rearranging the compounds represented by the following formulae in the presence of a base and a cyanogen compound




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In the respective formulae, R1, R5, R6, R7, R8, R9, R10, R11, and R12 have the same meanings as the aforementioned.


Manufacturing Method (b)

In the case that compounds in which Q represents Q3 and R15 represents hydrogen are manufactured: a method for reacting the compounds represented by the following formulae with hydroxylamine hydrochloride




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In the respective formulae, R1 and R14 have the same meanings as the aforementioned.


Manufacturing Method (c)

In the case that compounds in which Q represents Q3 and R15 represents alkoxycarbonyl are manufactured: a method for reacting the compounds represented by the following formula (IX) with imidoyl chloride represented by the following formula (X)




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In the formula, R1 and R14 have the same meanings as the aforementioned.




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In the formula, R16 represents alkoxycarbonyl.


Manufacturing Method (d)

In the case that compounds in which Q represents Q3 and R15 represents alkoxycarbonyl are manufactured: a method for reacting the compounds represented by the following formula with 1H-1,2,4-triazole in the presence of a base




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In the formula, R1, R14, and R16 have the same meanings as the aforementioned.


Manufacturing Method (e)

In the case that compounds in which Q represents Q3 and R15 represents alkylthio are manufactured: a method for reacting the compound represented by the following formula with hydroxylamine hydrochloride




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In the formula, R1 and R14 have the same meanings as the aforementioned and R17 represents alkylthio.


Manufacturing Method (f)

In the case that compounds in which Q represents Q4 are manufactured: a method for reacting the compounds represented by the following formula (XIII) with the compounds represented by the following formula (XIV) in the presence of a base




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In the formula, R1 has the same meanings as the aforementioned and X represents halogen.




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In the formula, R14 has the same meanings as the aforementioned.


Manufacturing Method (g)

In the case that compounds in which Q represents Q4 are manufactured: a method for causing the ring-opening reaction of the compounds represented by the following formula in the presence of a base




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In the formula, R1 and R14 have the same meanings as the aforementioned.


Manufacturing Method (h)

In the case that compounds in which Q represents Q1 and R4 represents halogen are manufactured: a method for reacting the compounds represented by the following formula with a halogenating agent




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In the formula, R1, R5, R6, R7, R8, R9, and R10 have the same meanings as the aforementioned.


Manufacturing Method (i)

In the case that compounds in which Q represents Q1 and R4 represents alkylthio, substituted phenylthio, substituted benzylthio, substituted pyrazol-1-yl, substituted imidazol-1-yl, 1,2,4-triazol-1-yl, 1H-tetrazol-1-yl, or 2H-tetrazol-2-yl are manufactured: a method for reacting the compounds represented by the following formula (XVII) with the compounds represented by the following formula (XVIII)




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In the formula, R1, R5, R6, R7, R8, R9, R10 and X have the same meanings as the aforementioned.





R18—H  Formula (XVIII)


In the formula, R18 represents alkylthio, substituted phenylthio, substituted benzylthio, substituted pyrazol-1-yl, substituted imidazol-1-yl, 1,2,4-triazol-1-yl, 1H-tetrazol-1-yl, or 2H-tetrazol-2-yl.


Manufacturing Method (j)

In the case that compounds in which Q represents Q2 and R13 represents alkyl, alkenyl, alkynyl, aralkyl, alkylsulfonyl, substituted phenylsulfonyl, acyl, or acylalkyl are manufactured: a method for reacting the compounds represented by the following formula (XIX) with the compounds represented by the following formula (XX)




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In the formula, R1, R11, and R12 have the same meanings as the aforementioned.





R19—X  Formula (X)


In the formula, X has the same meanings as the aforementioned, and R19 represents alkyl, alkenyl, alkynyl, aralkyl, alkylsulfonyl, substituted phenylsulfonyl, acyl, or acylalkyl.


The triazolylpyridine ketones of formula (I) provided by the present invention show stronger herbicide action than any of compounds described in the above prior art documents and have extremely superior effects as selective herbicides that do not substantially cause phytotoxicity to crops, especially effective to the general of broad-leaved weeds such as morning glories, knotweed, nightshade, fat hen, velvet leaf, amaranthus or the like, and effective to warm-season gramineous weeds such as livid amaranthus, green bristle grass, southern crabgrass, wire grass or the like, and show extremely excellent effects as herbicides for dry field crops such as wheat, corn or the like.


In the present specification, “Alkyl”, for example, shows normal chain or branched chain C1-12 alkyl such as methyl, ethyl, n- or iso-propyl, n-, iso-, sec-, or tert-butyl, n-pentyl, n-hexyl, n-heptyl, n-octyl, n-nonyl, n-decyl, n-undecyl, n-dodecyl or the like, and is preferably C1-6 alkyl.


Moreover, for respective alkyl parts in respective groups having alkyls as a part of configuration, ones similar to those explained in the above “alkyl” can be exemplified.


“Acylamino”, for example, shows alkylcarbonylamino, cyclopropylcarbonylamino, and benzoylamino, and here, as for alkyl part, alkyl having the same meanings as those explained in the above “alkyl” can be exemplified.


“Halogen” and respective halogen parts in respective halogen substituted groups show fluorine, chlorine, bromine, and iodine, and preferably show fluorine, chlorine, and bromine.


“Cycloalkyl” and the cycloalkyl part in a group having cycloalkyl as a part of configuration show C3-8 cycloalkyl such as cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclooctyl or the like, and preferably show C3-7 cycloalkyl.


“Alkenyl” and the alkenyl part in a group having alkenyl as a part of configuration show C2-5 alkenyl such as vinyl, allyl, 1-propenyl, 1- (or 2-, or 3-)butenyl, 1-pentenyl or the like, and preferably show C2-4 alkenyl.


“Alkynyl” and the alkynyl part in a group having alkynyl as a part of configuration show C2-5 alkynyl such as ethynyl, propargyl, 1-propynyl, butan-3-ynyl, pentan-4-ynyl or the like, and preferably show C2-4 alkynyl.


“Aryl” and the aryl part of “aralkyl” show C6-12 aryl such as phenyl, tolyl, xylyl, naphthyl, biphenylyl or the like, and preferably show C6-8 aryl. Preferred examples of “aralkyl” include benzyl, α-methylbenzyl, and phenethyl.


In the compounds of formula (I) of the present invention, the following compounds are preferred in which


R1 represents C1-6 alkyl, C3-8 cycloalkyl, C3-8 cycloalkyl-C1-2 alkyl, C1-6 haloalkyl, C2-6 alkenyl, C2-6 alkynyl, C6-12 aryl, C6-12 aryl-C1-2 alkyl, C1-6 haloalkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkoxy-C1-4 alkyl, C2-6 alkenyloxy-C1-4 alkyl, C2-6 alkynyloxy-C1-4 alkyl, C1-6 alkylthio-C1-4 alkyl, C1-6 alkylsulfinyl-C1-4 alkyl, C1-6 alkylsulfonyl-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylthio-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkyl, C1-6 haloalkylthio-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkyl, C1-6 haloalkylthio-C1-4 alkyl, C1-6 haloalkylsulfinyl-C1-4 alkyl, C1-6 haloalkylsulfonyl-C1-4 alkyl, C2-6 alkenylthio-C1-4 alkyl, C2-6 alkenylsulfenyl-C1-4 alkyl, C2-6 alkenylsulfonyl-C1-4 alkyl, C2-6 alkynylthio-C1-4 alkyl, C2-6 alkynylsulfinyl-C1-4 alkyl, C2-6 alkynylsulfonyl-C3-4 alkyl, C1-6 alkoxy-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkoxy-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkoxy-C1-4 alkoxy-C1-4 alkyl, C2-6 alkenyloxy-C1-4 alkoxy-C1-4 alkyl, C2-6 alkynyloxy-C1-4 alkoxy-C1-4 alkyl, C1-6 alkylthio-C1-4 alkoxy-C1-4 alkyl, C1-6 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-6 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkylthio-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-6 alkenylthio-C1-4 alkoxy-C1-4 alkyl, C2-6 alkenylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-6 alkenylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-6 alkynylthio-C1-4 alkoxy-C1-4 alkyl, C2-6 alkynylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-6 alkynylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-5 cyclic ether-O—C1-4 alkyl, C2-5 cyclic ether-C1-4 alkoxy-C1-4 alkyl, C1-6 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylthio, C1-6 alkylsulfinyl, C1-6 alkylsulfonyl, C1-6 alkoxy, C1-6 haloalkoxy, C1-6 alkoxy-C1-4 alkoxy, or NR2R3, R2 and R3 respectively represent hydrogen or C1-6 alkyl, Q represents




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R4 represents hydroxy, halogen, C1-6 alkylthio, substituted phenylthio, substituted benzylthio, substituted-1-pyrazolyl, substituted-1-imidazolyl, 1,2,4-triazol-1-yl, 1H-tetrazol-1-yl, or 2H-tetrazol-2-yl,


R5, R6, R7, R8, R9, and R10 respectively represent hydrogen or C1-6 alkyl,


R5 and R10 together represent ethylene or —CH═CH—,


R7 and R8 together represent carbonyl,


R11 represents C1-6 alkyl,


R12 represents hydrogen, C1-6 alkyl, or C3-8 cycloalkyl,


R13 represents hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C6-10 aryl-C1-2 alkyl, C1-6 alkylsulfonyl, substituted phenylsulfonyl, C1-6 alkylcarbonyl, benzoyl, heteroarylcarbonyl, C1-6 alkyl-carbonyl-C1-4 alkyl, benzoyl-C1-4 alkyl, or heteroarylcarbonyl-C1-4 alkyl,


R14 represents C1-6 alkyl or C3-8 cycloalkyl, and R15 represents hydrogen, C1-6 alkoxy-carbonyl or C1-6 alkylthio.


Among the compounds of formula (I), the following compounds are especially preferred in which


R1 represents C1-4 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-C1-2 alkyl, C1-4 haloalkyl, C2-4 alkenyl, C2-4 alkynyl, C6-8 aryl, C6-8 aryl-C1-2 alkyl, C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkoxy-C1-4 alkyl, C2-4 alkenyloxy-C1-4 alkyl, C2-4 alkynyloxy-C1-4 alkyl, C1-4 alkylthio-C1-4 alkyl, C1-4 alkylsulfinyl-C1-4 alkyl, C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkyl, C1-4 haloalkylthio-C1-4 alkyl, C1-4 haloalkylsulfinyl-C1-4 alkyl, C1-4 haloalkylsulfonyl-C1-4 alkyl, C2-4 alkenylthio-C1-4 alkyl, C2-4 alkenylsulfinyl-C1-4 alkyl, C2-4 alkenylsulfonyl-C1-4 alkyl, C2-4 alkynylthio-C1-4 alkyl, C2-4 alkynylsulfinyl-C1-4 alkyl, C2-4 alkynylsulfonyl-C1-4 alkyl, C1-4 alkoxy-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkoxy-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkoxy-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenyloxy-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynyloxy-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylthio-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylsulfinyl-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylthio-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylthio-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenylthio-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylthio-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 cyclic ether-O—C1-4 alkyl, C2-4 cyclic ether-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylthio, C1-4 alkylsulfinyl, C1-4 alkylsulfonyl, C1-4 alkoxy, C1-4 haloalkoxy, C1-4 alkoxy-C1-4 alkoxy or NR2R3,


R2 and R3 respectively represent hydrogen or C1-4 alkyl, Q represents




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R4 represents hydroxy, halogen, C1-4 alkylthio, substituted phenylthio, substituted benzylthio, substituted-1-pyrazolyl, substituted-1-imidazolyl, 1,2,4-triazol-1-yl, 1H-tetrazol-1-yl, or 2H-tetrazol-2-yl,


R5, R6, R7, R8, R9 and R10 respectively represent hydrogen or C1-4 alkyl, R5 and R10 together represent ethylene or —CH═CH—,


R7 and R8 together represent carbonyl,


R11 represents C1-4 alkyl,


R12 represents hydrogen, C1-4 alkyl, or C3-7 cycloalkyl,


R13 represents hydrogen, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C6-8 aryl-C1-2 alkyl, C1-4 alkylsulfonyl, substituted phenylsulfonyl, C1-4 alkylcarbonyl, benzoyl, heteroarylcarbonyl, C1-4 alkyl-carbonyl-C1-4 alkyl, benzoyl-C1-4 alkyl, or heteroarylcarbonyl-C1-4 alkyl,


R14 represents C1-4 alkyl or C3-7 cycloalkyl, and R15 represents hydrogen, C1-4 alkoxy-carbonyl or C1-4 alkylthio.


The case in which, for example, 3-oxo-1-cyclohexen-1-yl 2-methyl-6-(1H-1,2,4-triazole-1-yl)nicotinate is used as a raw material and acetocyanhydrin is used as a cyanogen compound in the manufacturing method (a) can be represented by the following reaction formula.




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The case in which, for example, 1-cyclopropyl-2-[(dimethylamino)methylene]-3-(2-methyl-6-(1H-triazol-1-yl)pyridin-3-yl)propan-1,3-dione and hydroxylamine hydrochloride are used as raw materials in the manufacturing method (b) can be represented by the following reaction formula.




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The case in which, for example, 1-cyclopropyl-3-(2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl)propan-1,3-dione and ethyl chlorooxyimidoacetate are used as raw materials in the manufacturing method (c) can be represented by the following reaction formula.




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The case in which, for example, ethyl 4-[(6-chloro-2-methylpyridin-3-yl)carbonyl]-5-cyclopropylisooxazole-3-carboxylic acid ester and triazole are used as raw materials and, for example, potassium carbonate is used as a base in the manufacturing method (d) can be represented by the following reaction formula.




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The case in which, for example, 2-[bis(methylthio)methylene]-1-cyclopropyl-3-[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]-1-propan-1,3-dione and hydroxylamine hydrochloride are used as raw materials in the manufacturing method (e) can be represented by the following reaction formula.




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The case in which, for example, 2-methyl-6-(1H-1,2,4-triazol-1-yl)nicotinic acid chloride is used as a raw material and, for example, sodium hydride is used as a base in the manufacturing method (f) can be represented by the following reaction formula.




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The case in which, for example, (5-cyclopropylisooxazol-4-yl)[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone is used as a raw material, and, for example, triethylamine is used as a base in the manufacturing method (g) can be represented by the following reaction formula.




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The case in which, for example, 2-{[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]}cyclohexan-1,3-dione is used as a raw material and, for example, oxalyl dichloride is used as a chlorinating agent in the manufacturing method (h) can be represented by the following reaction formula.




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The case in which, for example, 3-chloro-2-([2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-ylcarbonyl])-2-cyclohexen-1-one and thiophenol are used as raw materials in the manufacturing method (i) can be represented by the following reaction formula.




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The case in which, for example, (5-hydroxy-1-methyl-1H-pyrazol-4-yl)[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone and phenacyl bromide are used as raw materials, and, for example, potassium carbonate is used as a base in the manufacturing method (j) can be represented by the following reaction formula.




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The compounds of formulae (II), (III), and (IV) serving as the raw materials in the manufacturing method (a) are novel ones, and can be obtained by reacting the compounds represented by the following formula (XXI) with the compounds represented by the following formula (XXII) or (XXIII).




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In the formula, R1 has the same meanings as the aforementioned.




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In the formula, R5, R6, R7, R8, R9 and R10 have the same meanings as the aforementioned.




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In the formula, R11 and R12 have the same meanings as the aforementioned.


The compounds of formula (XXI) are novel ones, and can be obtained by reacting the compounds represented by the following formula with thionyl chloride.




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In the formula, R1 has the same meanings as the aforementioned.


The compounds of formula (XXIV) are novel ones, and can be obtained by hydrolyzing the compounds represented by the following formula.




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In the formula, R1 has the same meanings as the aforementioned.


The compounds of formula (XXV) are obtained by reacting the compounds represented by the following formula with 1H-1,2,4-triazole.




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In the formula, R1 has the same meanings as the aforementioned.


The compounds of formula (XXVI) are obtained, for example, by reacting the compounds represented by the following formula with phosphorus oxychloride. (Refer to J. Org. Chem., 1954, vol. 19, No. 2, pages 183-193).




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In the formula, R1 has the same meanings as the aforementioned.


Among compounds of formula (XXVII), for example, 6-oxo compound that is the tautomer of a compound of formula (XXVII) in which R1 is methyl is a publicly known compound described in J. Org. Chem., 1954, vol. 19, No. 2, pages 183-193.


Moreover, the tautomer of a compound of formula (XXVII) in which R1 is trifluoromethyl is a publicly known compound described in WO2004/029027 or the like.


Among compounds of formula (XXIV), for example, a compound of formula (XXIV) in which R1 is methoxymethyl, trifluoroethoxymethyl, or 2-(methoxy)ethoxymethyl can be obtained by reacting the compound of formula (XXV) in which R3 is bromomethyl with corresponding metal alkoxide, and subsequently by hydrolyzing the resultant product without isolating the product.


Moreover, the compound of formula (XXIV) in which R1 is 2-(methoxy)ethoxymethyl can be synthesized by continuously subjecting ethyl 2-(bromomethyl)-6-chloronicotinate corresponding to formula (XXVI) in which R3 is bromomethyl to a three-step reaction of alkoxyalkylation, triazolylation, and hydrolysis without isolating the intermediate products.


Among compounds of formula (XXV), for example, the compound of formula (XXV) in which R1 is methylthiomethyl can be obtained by reacting the compound of formula (XXV) in which R1 is bromomethyl with corresponding metal thioalkoxide. Moreover, by oxidizing this methylthiomethyl compound, the compound of formula (XXV) in which R3 is methylsulfonylmethyl can also be obtained.


Compounds of formulae (XXII) and (XXIII) are publicly known compounds.


Typical examples of the compounds of formula (XXII) include the following.


Cyclohexan-1,3-dione, 4-methylcyclohexan-1,3-dione, 4,4-dimethylcyclohexan-1,3-dione, 2,2,4,4-tetramethylcyclohexan-1,3,5-trione, bicyclo[3.2.1]octan-2,4-dione, bicyclo[3.2.1]-6-octen-2,4-dione.


Moreover, typical examples of the compounds of formula (XXIII) include the following.


1-Methyl-1H-pyrazol-5-ol, 1-ethyl-1H-pyrazol-5-ol, 1,3-dimethyl-1H-pyrazol-5-ol, 3-cyclopropyl-1-methyl-1H-pyrazol-5-ol.


Typical examples of the compounds of formulae (II), (III), and (IV) as the raw materials in the manufacturing method (a) include the following.

  • 3-Oxo-1-cyclohexen-1-yl
  • 2-(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)nicotinate,
  • 3-oxo-1-cyclohexen-1-yl
  • 2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)nicotinate,
  • 4,4-dimethyl-3-oxo-1-cyclohexen-1-yl
  • 2-methyl-6-(1H-1,2,4-triazol-1-yl)nicotinate,
  • 4-oxobicyclo[3.2.1]-2-octen-2-yl
  • 2-methyl-6-(1H-1,2,4-triazol-1-yl)nicotinate,
  • 1-ethyl-1H-pyrazol-5-yl
  • 2-methyl-6-(1H-1,2,4,-triazol-1-yl)nicotinate,
  • 1,3-dimethyl-1H-pyrazol-5-yl
  • 2-(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)nicotinate,
  • 3-cyclopropyl-1-methyl-1H-pyrazol-5-yl
  • 2-methyl-6-(1H-1,2,4-triazol-1-yl)nicotinate,
  • 1-methyl-1H-pyrazole-5-yl
  • 2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)nicotinate.


The compounds of formulae (V) and (VI) as the raw materials in the manufacturing method (b) are novel ones, and, for example, can be obtained as a mixture of formulae (V) and (VI) by reacting the compounds of formula (IX) with dimethylformamide dimethylacetal.


Moreover, the compounds of formulae (VII) and (VIII) are also novel ones, and can be obtained as a mixture of formulae (VII) and (VIII) by reacting the compounds of formula (IX) with ethyl orthoformate.


The compounds of formula (V) and the compounds of formula (VI), and the compounds of formula (VII) and the compounds of formula (VIII) are geometrical isomers.


Typical examples of compounds of formulae (V), (VI), (VII), and (VIII) as the raw materials in the manufacturing method (b) include the following.

  • (2E)-1-cyclopropyl-2-[(dimethylamino)methylene]-3-[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]propan-1,3-dione,
  • (2E)-1-cyclopropyl-2-[(dimethylamino)methylene]-3-[2-methyl-6-(1H-1,2,4-triazole-1-yl)pyridin-3-yl]propan-1,3-dione,
  • (2E)-1-cyclopropyl-2-[(dimethylamino)methylene]-3-[2-(methoxymethyl)-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl]propan-1,3-dione,
  • (2E)-2-[(dimethylamino)methylene]-4,4-dimethyl-1-[2-methyl-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl]pentan-1,3-dione,
  • (2E)-1-cyclopropyl-2-[(dimethylamino)methylene]-3-(2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl)propane-1,3-dione,
  • (2E)-1-cyclopropyl-2-[(dimethylamino)methylene]-3-[6-(1H-1,2,4-triazole-1-yl)-2-(trifluoromethyl)pyridin-3-yl]propan-1,3-dione,
  • (2Z)-1-cyclopropyl-2-[(dimethylamino)methylene]-3-[2-(methoxymethyl)-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl]propane-1,3-dione,
  • (2Z)-1-cyclopropyl-2-[(dimethylamino)methylene)-3-(2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]propan-1,3-dione,
  • (2Z)-2-[(dimethylamino)methylene]-4,4-dimethyl-1-[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]pentan-1,3-dione,
  • (2Z)-1-cyclopropyl-2-[(dimethylamino)methylene]-3-(2-[(methylthio)methyl]-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl)propane-1,3-dione),
  • (2Z)-1-cyclopropyl-2-[(dimethylamino)methylene]-3-[6-(1H-1,2,4-triazol-1-yl)-2-(trifluoromethyl)pyridin-3-yl]propan-1,3-dione,
  • (2E)-1-cyclopropyl-2-(ethoxymethylene)-3-[2-(methoxymethyl)-6-(1H-1,2,4-triazole-1-yl)pyridin-3-yl]propan-1,3-dione,
  • (2E)-1-cyclopropyl-2-(ethoxymethylene)-3-[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]propan-1,3-dione,
  • (2E)-2-(ethoxymethylene)-4,4-dimethyl-1-[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]pentan-1,3-dione,
  • (2E)-1-cyclopropyl-2-(ethoxymethylene)-3-(2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl)propan-1,3-dione,
  • (2E)-1-cyclopropyl-2-(ethoxymethylene)-3-[6-(1H-1,2,4-triazol-1-yl)-2-(trifluoromethyl)pyridin-3-yl]propan-1,3-dione,
  • (2Z)-1-cyclopropyl-2-(ethoxymethylene)-3-[2-(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]propane-1,3-dione,
  • (2Z)-1-cyclopropyl-2-(ethoxymethylene)-3-[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]propane-1,3-dione,
  • (2Z)-2-(ethoxymethylene)-4,4-dimethyl-1-[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]pentan-1,3-dione,
  • (2Z)-1-cyclopropyl-2-(ethoxymethylene)-3-(2-[(methylthio)methyl]-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl)propan-1,3-dione,
  • (2Z)-1-cyclopropyl-2-(ethoxymethylene)-3-[6-(1H-1,2,4,-triazol-1-yl)-2-(trifluoromethyl)pyridin-3-yl]propan-1,3-dione.


The compounds of formula (IX) as the raw material in the manufacturing method (c) are novel ones, and can be obtained, for example, by reacting the compounds represented by the following formula with acid.




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In the formula, R1 and R14 have the same meanings as the aforementioned.


The compounds of formula (XXVIII) can be obtained by reacting the compounds of the formula (XXI) with the compounds represented by the following formula.




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In the formula, R14 has the same meanings as the aforementioned.


The compounds of formula (XXIX) are publicly known compounds described in WO99/03856.


The acid reacted with the compounds of formula (XXVIII) is, for example, hydrochloric acid, sulfuric acid, or trifluoro acetic acid.


Typical examples of the compounds of formula (IX) as the raw material in the manufacturing method (c) include the following.

  • 1-Cyclopropyl-3-[6-(1H-1,2,4-triazol-1-yl)-2-(trifluoromethyl)pyridin-3-yl]propane-1,3-dione,
  • 1-cyclopropyl-3-[2-(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]propan-1,3-dione,
  • 4,4-dimethyl-1-[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]pentan-1,3-dione,
  • 1-cyclopropyl-3-(2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl)propan-1,3-dione.


The compounds of formula (X) as the raw material in the manufacturing method (c) are imidoyl chlorides well known in organic chemistry, and a typical example thereof is ethyl 2-chloro-2-(hydroxyimino)acetate.


The compounds of formula (XI) as the raw material in the manufacturing method (d) are novel ones, and can be obtained, for example, by reacting the compounds represented by the following formula with the compounds of formula (X).




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In the formula, R1 and R14 have the same meanings as the aforementioned.


The compounds of formula (XXX) are novel ones, and can be obtained, for example, by reacting the compounds represented by the following formula with acid.




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In the formula, R1 and R14 have the same meanings as the aforementioned.


The compounds of formula (XXXI) are novel ones, and can be obtained, for example, by reacting the compounds represented by the following formula with the compounds represented by formula (XXIX).




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In the formula, R1 has the same meanings as the aforementioned.


The compounds of formula (XXXII) can be obtained easily by hydrolyzing the compounds of the formula (XXVI), and subsequently reacting the obtained compounds with thionyl chloride.


Among compounds of formula (XXXII), the compound in which R1 is methyl is publicly known one described in Japanese Patent Laid-Open No. 3-38586, and the compound in which R1 is methoxy is publicly known one described in Japanese Patent Laid-Open No. 52-3968.


As the acid to be reacted with the compounds of formula (XXXI), compounds the same as those explained in the manufacturing method (c) can be used.


Typical examples of the compounds of formula (XI) as the raw material in the manufacturing method (d) include the following.


Ethyl 4-([6-chloro-2-(trifluoromethyl)pyridin-3-yl]carbonyl-5-cyclopropylisooxazole-3-carboxylic acid ester, ethyl 5-tert-butyl-4-[(6-chloro-2-methylpyridin-3-yl)carbonyl]isooxazole-3-carboxylic acid ester.


The compounds of formula (XII) as the raw material in the manufacturing method (e) are novel ones, and can be obtained, for example, by reacting the compounds represented by formula (IX) with carbon disulfide and methyl iodide in the presence of potassium fluoride carried by alumina.


Typical examples of the compounds of formula (XII) include the following:

  • 2-[Bis(methylthio)methylene]-1-cyclopropyl-3-[6-(1H-1,2,4-triazol-1-yl)-2-(trifluoromethyl)pyridin-3-yl]propan-1,3-dione,
  • 2-[bis(methylthio)methylene]-1-[2-(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]-4,4-dimethylpentan-1,3-dione,
  • 2-[bis(methylthio)methylene]-1-cyclopropyl-3-[2-(methoxymethyl)-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl]propan-1,3-dione,
  • 2-[bis(methylthio)methylene]-1-cyclopropyl-3-(2-[(methylthio)methyl]-6-(1H-1,2,4,-triazol-3-yl)pyridin-3-yl)propan-1,3-dione.


The compounds of formula (XIII) as the raw material in the manufacturing method (f) include the compounds of formula (XXI) and are novel ones, and their representative ones are compounds corresponding to the compounds of formula (XXI).


Typical examples of the compounds of formula (XIII) include the following.

  • 2-(Methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)nicotinic acid chloride,
  • 6-(1H-1,2,4-triazol-1-yl)-2-(trifluoromethyl)nicotinic acid chloride,
  • 2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)nicotinic acid chloride,
  • 6-(1H-1,2,4-triazol-1-yl)-2-[(2,2,2-trifluoroethoxy)methyl]nicotinic acid chloride,
  • 2-[(2-methoxyethoxy)methyl]-6-(1H-1,2,4-triazol-1-yl)nicotinic acid chloride.


Similarly, the compounds of formula (XIV) as the raw material in the manufacturing method (f) are publicly known ones, and examples thereof include the following compounds. 3-Oxobutanenitrile, 3-oxopentanenitrile, 3-cyclopropyl-3-oxopropanenitrile, 4,4-dimethyl-3-oxopentanenitrile.


The compounds of formula (XV) as the raw material in the manufacturing method (g) corresponds to the compounds in which Q is Q3 and R15 is hydrogen in the formula (I) of the present invention.


The compounds of formula (XV) can be obtained by the manufacturing method (b).


Typical examples of the compounds of formula (XV) include the following.

  • (5-Cyclopropylisooxazol-4-yl)[2-(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone,
  • (5-cyclopropylisooxazol-4-yl){2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl}methanone,
  • (5-cyclopropylisooxazol-4-yl)[6-(1H-1,2,4-triazol-1-yl)-2-(trifluoromethyl)pyridin-3-yl]methanone,
  • (5-tert-butylisooxazol-4-yl)[2-methyl-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl]methanone.


The compounds of respective formulae (XVI), (XVII), and (XIX) as the raw materials in the manufacturing methods of (h), (i), and (j) are also included in the formula (I) of the present invention, and can be obtained by the manufacturing method (a).


Typical examples of the compounds of formula (XVI) include the following.

  • 2-{[6-(1H-1,2,4-triazol-1-yl)-2-(trifluoromethyl)pyridin-3-yl]carbonyl}cyclohexan-1,3-dione,
  • 2-{[2-(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]carbonyl}cyclohexan-1,3-dione,
  • 2-({2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl}carbonyl)cyclohexan-1,3-dione,
  • 4,4-dimethyl-2-{[2-methyl-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl]carbonyl}cyclohexan-1,3-dione,
  • 3-{[2-methyl-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl]carbonyl}bicyclo[3.2.1]octan-2,4-dione.


Typical examples of the compounds of formula (XVII) include the following.

  • 3-Chloro-2-([6-(1H-1,2,4-triazol-1-yl)-2-(trifluoromethyl)pyridin-3-yl]carbonyl-2-cyclohexen-1-one,
  • 3-chloro-2-([2-(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]carbonyl)-2-cyclohexen-1-one,
  • 3-chloro-2-({2-[(methylthio)methyl]-6-(1H-1,2,4-triazol-1-yl)pyridine-3-yl}carbonyl)-2-cyclohexen-1-one,
  • 4-chloro-3-([2-methyl-6-(1H-1,2,4,-triazol-1-yl)pyridin-3-yl]carbonyl)bicyclo[3.2.1]-3-octen-2-one.


Typical examples of the compounds of formula (XIX) include the following.

  • (1-Ethyl-hydroxy-1H-pyrazol-4-yl)[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone,
  • (5-hydroxy-1,3-dimethyl-1H-pyrazol-4-yl)[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone,
  • (3-cyclopropane-5-hydroxy-1-methyl-1H-pyrazol-4-yl)[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone,
  • (5-hydroxy-1-methyl-1H-pyrazol-4-yl)[(methoxymethyl)-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone.


The halogenating agent in the manufacturing method (h), the compounds of formula (XVIII) as the raw material in the manufacturing method (i), and the compounds of formula (XX) as the raw material in the manufacturing method (j) are well known.


As the halogenating agent, the following ones can be used.


Phosphorus oxychloride, phosphorus oxybromide, phosphorus trichloride, phosphorus tribromide, oxalyl dichloride, oxalyl dibromide,-thionyl chloride, and thionyl bromide.


Examples of the compounds of formula (XVIII) include the following.


Methanethiol, thiophenol, benzylthiol, imidazole, pyrazole, 1,2,4-triazole, and tetrazole.


Examples of the compounds of formula (XX) include the following.


Iodomethane, allyl bromide, propargyl bromide, benzyl bromide, methanesulfonyl chloride, ethanesulfonyl chloride, propanesulfonyl chloride, benzenesulfonyl chloride, p-toluenesulfonyl chloride, and phenacyl chloride.


The reaction of the manufacturing method (a) can be carried out in a suitable diluent, and examples of the diluent include aliphatic, cycloaliphatic, and aromatic hydrocarbons (that are chlorinated in some cases), for example, toluene, dichloromethane, chloroform, and 1,2-dichloroethane; ethers, for example, ethyl ether, dimethoxyethane (DME), and tetrahydrofuran (THF); ketones, for example, methyl isobutyl ketone (MIBK); nitriles, for example, acetonitrile; esters, for example, ethyl acetate; acid amides, for example, dimethylformamide (DMF).


The manufacturing method (a) can be carried out in the presence of a cyanogen compound and a base, and examples of the cyanide compound include sodium cyanide, potassium cyanide, acetone cyanohydrin, and hydrogen cyanide. Examples of the base include inorganic bases such as hydroxides and carbonates of alkaline metals and alkaline earth metals, for example, sodium carbonate, potassium carbonate, lithium hydroxide, sodium hydroxide, potassium hydroxide, and calcium hydroxide; and organic bases such as tertiary amines, dialkylaminoanilines, and pyridines, for example, triethylamine, pyridine, 4-dimethylaminopyridine (DMAP), 1,4-diazabicyclo[2,2,2]octane (DABCO), and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU).


The manufacturing method (a) can be carried out by adding a phase transfer catalyst, and examples of the phase transfer catalysts include crown ethers, for example, dibenzo-18-crown-6, 18-crown-6, and 15-crown-5.


The manufacturing method (a) can be carried out in a substantially wide temperature range. The temperature is generally from about −10 to about 80° C., and preferably from about 5 to about 40° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can also be carried out under pressure or under reduced pressure in some cases.


In the manufacturing method (a), a target compound of formula (I) can be obtained, for example, by reacting 1 to 4 mol of triethylamine with 1 mol of a compound of formula (II) in a diluent, for example, acetonitrile, in the presence of 0.01 to 0.5 mol of acetone cyanohydrin.


When rearrangement reaction of the compounds of formula (IV) are carried out in the manufacturing method (a), the rearrangement of the compound of formula (IV) can be conducted in the presence of a base.


Such a reaction can be carried out in an appropriate diluent, and examples of the diluent include ethers, for example, dioxane, and tetrahydrofuran (THF); and alcohols, for example, tert-amylalcohol, and tert-butylalcohol.


Moreover, examples of the base include inorganic bases such as carbonates of alkaline metals, for example, sodium carbonate, and potassium carbonate; and organic bases, such as tertiary amines, for example, triethylamine, pyridine, and 4-dimethylaminopyridine (DMAP).


The reaction can be carried out in a substantially wide temperature range, and the temperature is generally from about 5 to about 200° C., and preferably from about 25 to about 130° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can be carried out under pressure or under reduced pressure in some cases.


In the reaction, a target compound of formula (I) can be obtained, for example, by reacting 0.5 to 2 mol of potassium carbonate with 1 mol of the compound of formula (IV) in a diluent, for example, dioxane.


The reaction of the manufacturing method (b) can be carried out in an appropriate diluent, and examples of the diluent include aliphatic, cycloaliphatic, and aromatic hydrocarbons (that may be chlorinated in some cases), for example, toluene, dichloromethane, chloroform, and 1,2-dichloroethane; ethers, for example, tetrahydrofuran (THF); nitriles, for example, acetonitrile; and alcohols, for example, methanol, ethanol, and isopropanol.


The manufacturing method (b) can be carried out in a substantially wide temperature range. The temperature is generally from about −10 to about 100° C., and preferably from about 0 to about 50° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can be carried out under pressure or under reduced pressure in some cases.


In the manufacturing method (b), a target compound of the formula (I) can be obtained, for example, by reacting 1 to 1.5 mol of hydroxylamine hydrochloride with 1 mol of the compound of formula (V) in a diluent, for example ethanol, in the presence of 1 to 1.5 mol of sodium acetate.


The manufacturing method (b) can be successively carried out without isolating the compounds of formulae (V), (VI), (VII) and (VIII), and a target compound of formula (I) can be obtained.


The reaction of the manufacturing method (c) can be carried out in an appropriate diluent, and examples of the diluent include aliphatic, cycloaliphatic, and aromatic hydrocarbons (that may be chlorinated in some cases), for example, toluene, dichloromethane, chloroform, and 1,2-dichloroethane; ethers, for example, tetrahydrofuran (THF); nitriles, for example, acetonitrile; and alcohols, for example, methanol, ethanol, and isopropanol.


The manufacturing method (c) can be carried out in the presence of a base, and examples of the bases include inorganic bases such as acetates, carbonates, and bicarbonates of alkaline metals and alkaline earth metals, for example, sodium acetate, sodium hydrogen carbonate, potassium hydrogen carbonate, sodium carbonate, and potassium carbonate; and organic bases such as tertiary amines, dialkylaminoanilines, and pyridines, for example, triethylamine, pyridine, and 4-dimethylaminopyridine (DMAP).


The manufacturing method (c) can be carried out in a substantially wide temperature range. The temperature is generally from about −10 to about 100° C., and preferably from about 0 to about 50° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can be carried out under pressure or under reduced pressure in some cases.


In the manufacturing method (c), a target compound of the formula (I) can be obtained, for example, by reacting 1 to 1.5 mol of the compound of formula (X) with 1 mol of the compound of formula (IX) in a diluent, for example, toluene.


The reaction of the manufacturing method (d) can be carried out in an appropriate diluent, and examples of the diluent include aliphatic, cycloaliphatic, and aromatic hydrocarbons (that may be chlorinated in some cases), for example, pentane, hexane, cyclohexane, petroleum ether, ligroin, benzene, toluene, xylene, dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, chlorobenzene, and dichlorobenzene; ethers, for example, ethyl ether, methyl ethyl ether, isopropyl ether, butyl ether, dioxane, dimethoxyethane (DME), tetrahydrofuran (THF), and diethylene glycol dimethyl ether (DGM); ketones, for example, acetone, methyl ethyl ketone (MEK), methyl isopropyl ketone, and methyl isobutyl ketone (MIBK); nitriles, for example, acetonitrile, propionitrile, and acrylonitrile; esters, for example, ethyl acetate, and amyl acetate; acid amides, for example, dimethylformamide (DMF), dimethylacetamide (DMA), N-methylpyrolidone, 1,3-dimethyl-2-imidazolidinone, and hexamethylphosphoric triamide (HMPA); sulfones and sulfoxides, for example, dimethyl sulfoxide (DMSO), and sulfolane; and bases, for example, pyridine.


The manufacturing method (d) can be carried out in the presence of an acid binding agent, and examples of such an acid binding agent include inorganic bases, such as hydrides, hydroxides, carbonates and bicarbonates of alkaline metals and alkaline earth metals, for example, sodium hydride, lithium hydride, sodium hydrogen carbonate, potassium hydrogen carbonate, sodium carbonate, potassium carbonate, lithium hydroxide, sodium hydroxide, potassium hydroxide, and calcium hydroxide; inorganic alkaline metal amides, for example, lithium amide, sodium amide, and potassium amide; organic bases such as alcoholate, tertiary amines, dialkylaminoanilines and pyridines, for example, triethylamine, 1,1,4,4-tetramethylethylenediamine (TMEDA), N,N-dimethylaniline, N,N-diethylaniline, pyridine, 4-dimethylaminopyridine (DMAP), 1,4 diazabicyclo[2,2,2]octane (DABCO), and 1,8-diazabicyclo[5,4,0]undec-7-ene (DBU); and organic lithium compounds, for example, methyl lithium, n-butyl lithium, sec-butyl lithium, tert-butyl lithium, phenyl lithium, dimethyl copper lithium, lithium diisopropylamide, lithium cyclohexylisopropylamide, lithium dicyclohexylamide, n-butyl lithium/DABCO, n-butyl lithium/DBU, and n-butyl lithium/TMEDA.


The manufacturing method (d) can be carried out in a substantially wide temperature range. It is generally carried out between about 25 and about 180° C., preferably between about 50 and about 180° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can also be carried out under pressure or under reduced pressure.


In the manufacturing method (d), a target compound can be obtained, for example, by reacting 1 mol to 5 mol of 1H-1,2,4-triazole with 1 mol of the compound of formula (XI) in a diluent, for example, dimethylformamide in the presence of a base, for example, potassium carbonate.


The reaction of the manufacturing method (e) can be carried out under conditions similar to those of the manufacturing method (b).


The manufacturing method (f) can be carried out in an appropriate diluent, and examples of the diluent include aliphatic, cycloaliphatic, and aromatic hydrocarbons (that may be chlorinated in some cases), for example, pentane, hexane, cyclohexane, petroleum ether, ligroin, benzene, toluene, xylene, dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, chlorobenzene, and dichlorobenzene; ethers, for example, ethyl ether, methyl ethyl ether, isopropyl ether, butyl ether, dioxane, dimethoxyethane (DME), tetrahydrofuran (THF), and diethylene glycol dimethyl ether (DGM); acid amides, for example, dimethylformamide (DMF), dimethylacetamide (DMA), N-methylpyrolidone, 1,3-dimethyl-2-imidazolidinone, and hexamethylphosphoric triamide (HMPA); sulfones and sulfoxides, for example, dimethylsulfoxide (DMSO), and sulfolane; and bases, for example, pyridine.


The manufacturing method (f) can be carried out in the presence of an acid binding agent, and examples of the acid binding agent include inorganic bases such as hydrides, hydroxides, carbonates, and bicarbonates of alkaline metals and alkaline earth metals, for example, sodium hydride, lithium hydride, sodium hydrogen carbonate, potassium hydrogen carbonate, sodium carbonate, potassium carbonate, lithium hydroxide, sodium hydroxide, potassium hydroxide, and calcium hydroxide; inorganic alkaline metal amides, for example, lithium amide, sodium amide, and potassium amide; organic bases such as alcoholate, tertiary amines, dialkylaminoanilins, and pyridines, for example, triethylamine, 1,1,4,4-tetramethylethylenediamine (TMEDA), N,N-dimethylaniline, N,N-diethylaniline, pyridine, 4-dimethylaminopyridine (DMAP), 1,4-diazabicyclo[2,2,2]octane (DABCO) and 1,8-diazabicyclo[5,4,0]undec-7-ene (DBU); and organic lithium compounds, for example, methyl lithium, n-butyl lithium, sec-butyl lithium, tort-butyl lithium, phenyl lithium, dimethyl copper lithium, lithium diisopropyl amide, lithium cyclohexylisopropylamide, lithium dicyclohexylamide, n-butyl lithium/DABCO, n-butyl lithium/DBU, and n-butyl lithium/TMEDA.


The manufacturing method (f) can be carried out in a substantially wide temperature range. It is generally carried out between about −70 and about 200° C., and preferably between about −50 and about 100° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can be carried out under pressure or under reduced pressure.


In manufacturing method (f), a target compound can be obtained, for example, by reacting 1 mol to 2 mol of the compound of formula (XIV) with 1 mol of the compound of formula (XIII) in a diluent, for example THF in the presence of 1.0 mol to 3 mol of sodium hydride.


The reaction of the manufacturing method (g) can be carried out in an appropriate diluent, and examples of the diluent include water; aliphatic, cycloaliphatic, and aromatic hydrocarbons (that may be chlorinated in some cases), for example, pentane, hexane, cyclohexane, petroleum ether, ligroin, benzene, toluene, xylene, dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, chlorobenzene, and dichlorobenzene; ethers, for example, ethyl ether, methyl ethyl ether, isopropyl ether, butyl ether, dioxane, dimethoxyethane (DME), tetrahydrofuran (THF), and diethylene glycol dimethyl ether (DGM); alcohols, for example, methanol, ethanol, isopropanol, butanol, and ethylene glycol; esters, for example, ethyl acetate, and amyl acetate; acid amides, for example, dimethylformamide (DMF), dimethylacetamide (DMA), N-methylpyrolidone, 1,3-dimethyl2-imidazolidinone, and hexamethylphosphoric triamide (HMPA); sulfones and sulfoxides, for example, dimethyl sulfoxide (DMSO), and sulfolane; and bases, for example, pyridine.


The manufacturing method (g) can be carried out in a substantially wide temperature range. It is generally carried out between about −70 and about 200° C., and preferably between about −30 and about 100° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can also be carried out under pressure or under reduced pressure.


In the manufacturing method (g), a target compound can be obtained, for example, by reacting 1 mol of the compound of formula (XV) in a diluent, for example, dichloromethane in the presence of 1 mol to 3 mol of triethylamine.


The reaction of the manufacturing method (h) can be carried out in an appropriate diluent, and examples of the diluent include aliphatic, cycloaliphatic, and aromatic hydrocarbons (that may be chlorinated in some cases), for example, pentane, hexane, cyclohexane, petroleum ether, ligroin, benzene, toluene, xylene, dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and chlorobenzene; ethers, for example, ethyl ether, methyl ethyl ether, isopropyl ether, butyl ether, dioxane, dimethoxyethane (DME), tetrahydrofuran (THF), and diethylene glycol dimethyl ether (DGM); ketones, for example, acetone, methyl ethyl ketone (MEK), methyl isopropyl ketone, and methyl isobutyl ketone (MIBK); nitriles, for example acetonitrile, and propionitrile; esters, for example, ethyl acetate, and amyl acetate; and acid amides, for example, dimethylformamide (DMF), dimethyl acetamide (DMA), N-methylpyrolidone, 1,3-dimethyl-2-imidazolidinone, and hexamethylphosphoric triamide (HMPA).


The reaction of the manufacturing method (h) can be carried out in a substantially wide temperature range. The temperature is generally from about −20 to about 100° C., and preferably about 0 to about 50° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can also be carried out under pressure or under reduced pressure in some cases.


In the manufacturing method (h), a target compound of formula (I) can be obtained, for example, by reacting 1 to 5 mol of oxalyl dichloride with 1 mol of the compound of formula (XVI) in a diluent, for example, dichloromethane.


The reaction of the manufacturing method (i) can be carried out in an appropriate diluent, and examples of the diluent include aliphatic, cycloaliphatic, and aromatic hydrocarbons (that may be chlorinated in some cases), for example, pentane, hexane, cyclohexane, petroleum ether, ligroin, benzene, toluene, xylene, dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, chlorobenzene, and dichlorobenzene; ethers, for example, ethyl ether, methyl ethyl ether, isopropyl ether, butyl ether, dioxane, dimethoxyethane (DME), tetrahydrofuran (THF), and diethylene glycol dimethyl ether (DGM): ketones, for example, acetone, methyl ethyl ketone (MEK), methyl isopropyl ketone, and methyl isobutyl ketone (MIBK); nitriles, for example, acetonitrile, propionitrile, and acrylonitrile; esters, for example, ethyl acetate, and amyl acetate; acid amides, for example, dimethylformamide (DMF), dimethylacetamide (DMA), and N-methylpyrolidone; sulfones and sulfoxides, for example, dimethlsulfoxide (DMSO), and sulfolane; and bases, for example, pyridine.


The manufacturing method (i) can be carried out in the presence of an acid binding agent, and examples of the acid binding agent include inorganic bases such as hydrides and carbonates of alkaline metals, for example, sodium hydride, lithium hydride, sodium carbonate, and potassium carbonate; and organic bases such as tertiary amines, dialkylaminoanilines and pyridines, for example, triethylamine, 1,1,4,4-tetramethylethylenediamine (TMEDA), pyridine, 4-dimethyaminopyridine (DMAP), 1,4-diazabicyclo[2,2,2]octane (DABCO), and 1,8-diazabicyclo[5,4,0]undec-7-ene (DBU).


The reaction of the manufacturing method (i) can be carried out in a substantially wide temperature range. The temperature is generally from about −20 to about 140° C., and preferably from about 0 to about 100° C. Moreover, it is desirable that the reaction is carried out under normal pressure, but the operation can also be carried out under pressure or under reduced pressure in some cases.


In the manufacturing method (i), a target compound of formula (I) can be obtained, for example, by reacting 1 to 5 mol of the compound of formula (XVIII) with 1 mol of the compound of formula (XVII) in a diluent, for example, tetrahydrofuran in the presence of 1 to 5 mol of triethylamine.


The reaction of the manufacturing method (j) can be carried out under conditions similar to those of the manufacturing method (h).


The active compound of formula (I) of the present invention shows excellent herbicide activity for various weeds as shown in biological test examples described later, and can be used as a herbicide. In the present specification, the weeds mean, in a broad sense, all plants growing in locations where they are undesired. The compound of the present invention acts as a selective herbicide depending on the application concentration. The active compound can be used, for example, between the following weeds and cultivated plants.


The Genus of Dicotyledonous Weeds:



Sinapis, Capsella, Leipidium, Galium, Stellaria, Chenopodium, Kochia, Urtica, Senecio, Amaranthus, Portulaca, Xanthium, Ipomoea, Polygonum, Ambrosia, Cirsium, Sonchus, Solanum, Rorippa, Lamium, Veronica, Datura, Viola, Galeopsis, Papaver, Centaurea, Galinsoga, Rotala, Lindernia, SeSbania, Trifolium, Abutilon, Lamium, Matricaria, Artemsia, Sesbania, Pharbitis, Amaranthus and the like.


The Genus of Dicotyledonous Cultivated Plants:



Gossypium, Glycine, Beta, Daucus, Phaseolus, Pisum, Solanum, Linum, Ipomoea, Vicia, Nicotiana, Lycopersicon, Arachis, Brassica, Lactuca, Cucumis, Cucurbita and the like.


The Genus of Monocotyledonous Weeds:



Echinochlona, Setaria, Panicum, Digitaria, Phleum, Poa, Festuca, Eleusine, Lolium, Bromus, Avena, Cyperus, Sorghum, Agropyron, Monochoria, Fimbristylis, Sagittaria, Eleocharis, Scirpus, Paspalum, Ischaemum, Agrostis, Alopecurus, Cynodon, Commelina, Brechiaria, Leptochloa, Echinochloa and the like.


The Genus of Monocotyledonous Cultivated Plants:



Oryza, Zea, Triticum, Hordeum, Avena, Secale, Sorghum, Panicum, Saccharum, Ananas, Asparagus, Allium and the like.


However, use of the active compound of formula (I) of the present invention is not limited only for weeds of these kinds of grasses, and can be applied similarly to weeds of other kinds of grasses.


Use of the compound of the present invention is not limited to the above plants and similarly applicable to other plants. Moreover, the active compounds of the present invention can non-selectively control weeds according to the application concentration, and can be used at, for example, an industrial site such as a factory, a railroad track, a road, a forested site, a non-forested site or the like. Furthermore, the active compounds of the present invention can be used to control weeds in perennial plant cultivation, and can be applied to, for example, planting, ornamental planting, orchard, grape vineyard, citrus orchard, nut orchard, banana plantation, coffee plantation, tea plantation, rubber plant plantation, guinea oil palm plantation, cocoa plantation, small orchard, hop plantation or the like, and, in annual plant cultivation, can also be applied to selectively control weeds.


The active compounds of the present invention, for actual use, can be prepared in customary formulations. Examples of the formulations include solution, wettable powder, emulsion, suspension, dust, water-dispersible granule, tablet, granule, suspended emulsifiable concentrate, and microcapsules in a polymer substance.


These formulations can be manufactured by known methods per se. For example, they can be prepared by mixing the active compounds with extenders, namely, liquid or solid diluents or carriers, and, optionally, with surfactants, namely emulsifiers and/or dispersants and/or foam-forming agents.


Examples of the liquid diluents or carriers include aromatic hydrocarbons (for example, xylene, toluene, and alkyl naphthalene), chlorinated aromatic or chlorinated aliphatic hydrocarbons (for example, chlorobenzenes, ethylene chlorides, and methylene chloride), aliphatic hydrocarbons [for example, cyclohexane, and paraffins (for example, mineral oil fraction)], alcohols (for example, butanol, and glycol) and ethers and esters thereof, ketones (for example, acetone, methyl ethyl ketone, methyl isobutyl ketone, and cyclohexanone), strongly polar solvents (for example, dimethylformamide, and dimethylsulfoxide), and water. In the case where water is used as an extender, for example, an organic solvent can be used as an auxiliary solvent.


Examples of the solid diluent or carrier include crushed natural mineral (for example, kaolin, clay, talc, chalk, quartz, attapulgite, montmorillonite, and diatomaceous earth), and crushed synthetic mineral (for example, high-dispersed silicic acid, alumina, and silicate). Examples of the solid carrier for use in granule include crushed and sorted rock (for example, calcite, marble, pumice, meerschaum, and dolomite), synthesized grain of inorganic and organic powder, fine granular body of organic material (for example, sawdust, shell of coco, corncob, and stem of cigarette).


Examples of the emulsifier and/or the foam-forming agent include nonionic and anionic emulsifiers [for example, polyoxyethylene fatty acid ester, polyoxyethylene fatty acid alcohol ether (for example, alkylaryl polyglycol ether, alkylsulfonate, alkylsulfate, and arylsulfonate)], and albumin hydrolysate.


As the decomposing agent, for example, lignin sulfite waste fluid and methyl cellulose are included.


A fixing agent can also be used in formulations (powder material, granule, and emulsion), and examples of the fixing agent include carboxymethylcellulose, and natural and synthetic polymer (for example, gum arabic, polyvinyl alcohol, and polyvinyl acetate).


A coloring agent can also be used and examples of the coloring agent include inorganic pigments (for example, iron oxide, titanium oxide, and Prussian blue), organic dyes such as alizarin dyes, azo dyes, and metal phthalocyanine dyes, and trace elements such as salts of metals including iron, manganese, boron, copper, cobalt, molybdenum, and zinc.


The formulations can generally contain the active compound(s) of formula (I) within a range of 0.1 to 95 wt %, and preferably contains the compound(s) within a range of 0.5 to 90 wt %.


The active compound of formula (I) of the present invention can be used for controlling weeds as such or in their formulation foams. Moreover, the active compound of formula (I) of the present invention can also be used in combination with a known herbicide. A mixed herbicide composition with a known herbicide may be previously prepared as a final formulation form, or can be prepared by tank-mixing on occasion of application.


For example, the following herbicides shown in common names can be exemplified as specific examples of herbicides that can be used in combination with the active compounds of formula (I) of the present invention.


Sulfonylurea herbicides: for example, chlorsulfuron, sulfometuron methyl, chlorimuron ethyl, triasulfuron, amidosulfuron, oxasulfuron, tribenuron ethyl, prosulfuron, ethametsulfuron methyl, triflusulfuron methyl, thifensuluron methyl, flazasulfuron, rimsulfuron, nicosulfuron, flupyrsulfuron, bensulfuron methyl, pyrazosulfuron ethyl, foramsulfuron, sulfosulfuron, cinosulfuron, azimsulfuron, metsulfuron-methyl, halosulfuron methyl, ethoxysulfuron, cyclosulfamuron, and iodosulfuron;


carbamate herbicides: for example, phenmedipham, chloropropham, asulam, benthiocarb, molinate, esprocarb, pyributicarb, dimepiperate, and swep;


chloroacetanilide herbicides: for example, propachlor, metazachlor, alachlor, acetochlor, metolachlor, butachlor, pretilachlor, and thenylchlor;


diphenylether herbicides: for example, acifluorfen, oxifluorfen, lactofen, fomesafen, aclonifen, chlomethoxynyl, bifenox, and CNP;


triazine herbicides: for example, simazine, atrazine, propazine, cyanazine, ametryn, simetryn, dimethametryn, and prometryn;


phenoxy acid or benzoic acid herbicides: for example, 2,3,6-TBA, dicamba, quinclorac, quinmerac, clopyralid, picloram, triclopyr, fluoroxypyr, fenoxaprop, diclofop methyl, fluazifop buthyl, haloxyfop methyl, quizalofop ethyl, cyhalofop butyl, 2,4-PA, MCP, MCPB, and phenothiol;


acid amide or urea herbicides: for example, izoxaben, diflufenican, diuron, linuron, fluometuron, difenoxuron, methyldymron, isoproturon, isouron, tebuthiuron, methabenzthiazuron, propanil, mefenacet, chlomeprop, naproanilide, bromobutide, dymron, cumyluron, etobenzanide, and oxaziclomefone;


organic phosphorus herbicides: for example, glyphosate, bialaphos, glufosinate, L-glufosinate, amiprofos methyl, anilofos, bensulide, piperophos, and butamifos;


dinitroaniline herbicides: for example, trifluralin, and prodiamine:


phenol herbicides: for example, bromoxynil, ioxynil, and dinoseb;


cyclohexanedione herbicides: for example, alloxydim, sethoxydim, cloproxydim, clethodim, cycloxydim, and tralkoxydim;


imidazolinone herbicides: for example, imazamethabenz, imazapyr, imazamethapyr, imazethapyr, imazamox, and imazaquin;


bipyridium herbicides: for example, paraquat, and diquat;


carbamoyltetrazolinone herbicides: for example, fentrazamide;


nitrile herbicides: cichlobenil; and


other herbicides: for example, bentazone, tridiphane, indanofan, amitrol, carfentrazone ethyl, sulfentrazone, fenchlorazol ethyl, isoxaflutole, clomazone, maleic acid hydrazide, pyridate, chloridazon, norflurazon, pyrithiobac, bromacil, terbacil, metribuzin, oxaziclomefone, cinmethylin, flumiclorac pentyl, flumioxazin, fluthiacet methyl, azafenidin, benfuresate, oxadiazon, oxadiargyl, pentoxazone, cafenstrole, pyriminobac, bispyribac sodium, pyribenzoxim, pyriftalid, pyraflufen ethyl, benzobicyclon, dithiopyr, dalapon, and chlorthiamid.


The above active compounds are known herbicides described in “Pesticide Manual”, published by British Crop Protect Council in 2000.


Moreover, when the active compounds of formula (I) of the present invention are blended with a phytotoxicity-reducing agent, phytotoxicity is reduced by this blending, and wider spectrum of weed controlling is provided, and thereby wider application as selective herbicide can be provided.


Examples of the phytotoxicity-reducing agent include the following compounds represented by general names or development codes.


AD-67, BAS-145138, benoxacor, cloquintocet-mexyl, cyometrinil, 2,4-D, DKA-24, dichlormid, dymron, fenchlorim, fenclorazole ethyl, flurazole, fluxofenim, furilazole, isoxadifen-ethyl, mefenpyr-diethyl, MG-191, naphthalic anhydride, oxabetrinil, PPG-1292, and R-29148.


The above phytotoxicity-reducing agent is also described in “Pesticide Manual” published by British Crop Protect Council in 2000.


Furthermore, the above phytotoxicity-reducing agent can be blended with a mixed herbicide composition containing the compound of formula (I) of the present invention and the above herbicide. By this blending, phytotoxicity is reduced and a wider spectrum of weed controlling is provided, and application as a selective herbicide can be made wider.


Surprisingly, a synergy effect can be demonstrated in several blending herbicide composition composed of the compounds of the present invention and known herbicides and/or phytotoxicity-reducing agents.


In the case that the active compounds of formula (I) of the present invention are used, these can be used directly as they are, or used in formulations such as prepared liquid for spraying, emulsion, tablet, suspension, powder, or granule, or application forms prepared by diluting. The active compounds of formula (I) of the present invention can be applied, for example, by the method of liquid agent scattering (watering), spraying, atomizing, or spreading granules.


The active compounds of formula (I) of the present invention can be used at every stage before germination or after germination of plant. Moreover, they can be taken into the soil prior to seeding.


The application amount of the active compounds of the present invention can be changed in a substantial range, and basically varies, depending on nature of desired effect. When the active compound is used as a herbicide, the application amount of the active compound per 1 hectare can be, for example, is about 0.005 to about 4 kg, and is preferably about 0.01 to about 2 kg.


Next, manufacturing and use of the compounds of the present invention are shown more concretely by the following examples, but the present invention should not be limited to only them.


EXAMPLES
Compound Example
Synthesis Example 1
Synthesis of 2-{[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]carbonyl}cyclohexan-1,3-dione



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To acetonitrile (5 ml) solution of 3-oxo-1-cyclohexen-1-yl 2-methyl-6-(1H-1,2,4-triazol-1-yl)nicotinate (0.13 g, 0.44 mmol) and triethylamine (0.09 g, 0.87 mmol), a catalytic amount of acetone cyanohydrine was added. The obtained solution was stirred at room temperature around the clock. Volatile materials were evaporated under reduced pressure from the obtained reaction solution, and the obtained residue was made acidic with citric acid aqueous solution, and was extracted with ethyl acetate. After washing the obtained organic layer with water, the organic layer was dried with magnesium sulfate and concentrated to obtain the desired product (0.1 g, yield 77%).



1H NMR (CDCl3, 300 MHz)


δ 2.02-2.16 (2H, m), 2.49 (3H, s), 2.45-2.59 (2H, m), 2.70-2.91 (2H, m), 7.59 (1H, d), 7.74 (1H, d), 8.09 (1H, s), 9.21 (1H, s)


Synthesis Example 2
Synthesis of (5-hydroxy-1-methyl-1H-pyrazol-4-yl)[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone



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To acetonitrile (5 ml) solution of 1-methyl-1H-pyrazole-5-yl 2-methyl-6-(1H-1,2,4-triazol-1-yl)nicotinate (0.19 g, 0.65 mmol) and triethylamine (0.13 g, 1.29 mmol), a catalytic amount of acetone cyanohydrin was added. The obtained solution was stirred at room temperature around the clock. Volatile materials were evaporated under reduced pressure from the obtained reaction solution, and the obtained residue was made acidic with citric acid aqueous solution, and was extracted with ethyl acetate. After washing the obtained organic layer with water, the organic layer was dried with magnesium sulfate and concentrated to obtain the desired product (0.18 g, yield 93%).



1H NMR (CDCl3, 300 MHz)


δ 2.71 (3H, s), 3.73 (3H, s), 7.43 (1H, s), 7.84 (1H, d), 8.00 (1H, d), 8.13 (1H, s), 9.25 (1H, s)


Synthesis Example 3
Synthesis of ethyl 5-cyclopropyl-4-[[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]carbonyl]isooxazole-3-carboxylic acid ester



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4-[(6-Chloro-2-methylpyridin-3-yl)carbonyl]-5-cyclopropylisooxazole-3-carboxylic acid ester (0.2 g, 0.6 mmol), triazole (0.08 g, 1.19 mmol) and potassium carbonate (0.17 g, 1.19 mmol) were stirred in DMF (5 ml) at 10° C. for four hours. To the obtained reaction solution, water and ethyl acetate were added. The organic layer was separated. Furthermore, water layer was extracted with ethyl acetate. After washing all the obtained organic layer with water, the organic layer was dried with magnesium sulfate and concentrated. The obtained residue was separated and purified by column chromatography to obtain the desired product (0.15 g, yield 68%).



1H NMR (CDCl3, 300 MHz)


δ 1.16-1.38 (7H, m), 2.30-2.39 (1H, m), 2.77 (3H, s), 4.10-4.17 (2H, q), 7.75 (1H, d), 7.85 (1H, d), 8.11 (1H, s), 9.24 (1H, s)


Synthesis Example 4
Synthesis of (5-cyclopropylisooxazol-4-yl)[2-methyl-6-(1H-1,2,4-triazol-1-yl)pyridin-3-yl]methanone



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To ethanol (5 ml) solution of 1-cyclopropyl-2-[(dimethylamino)methylene]-3-(2-methyl6-(1H-triazol-1-yl)pyridin-3-yl]propan-1,3-dione (0.29 g, 0.89 mmol), hydroxylamine hydrochloride (0.07 g, 0.98 mmol) was added. The obtained solution was stirred at room temperature around the clock. To obtained reaction solution, water and ethyl acetate were added. The organic layer was separated.


Furthermore, the water layer was extracted with ethyl acetate. All the obtained organic layer was washed with water, dried with magnesium sulfate and concentrated. The obtained residue was separated and purified by column chromatography to obtain the desired product (0.19 g, yield 72%).



1H NMR (CDCl3, 300 MHz)


δ 1.21-1.40 (4H, m), 2.60-2.73 (1H, m), 2.66 (3H, s), 7.82 (1H, d), 7.90 (1H, d), 8.11 (1H, s), 8.22 (1H, s), 9.22 (1H, a)


Synthesis Example 5
Synthesis of 3-cyclopropyl-2-{[2-methyl-6-(1H-1,2,4-triazol-1-yl)-pyridin-3-yl]carbonyl}-3-oxopropanenitrile



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A THF (2 ml) suspension of sodium hydride (0.06 g, 60% oil suspension, 18.78 mmol) was cooled in an ice bath, and a THF (2 ml) solution of 3-cyclopropyl-3-oxopropanenitrile was dripped thereto. To the obtained reaction solution, a THF (3 ml) solution of 2-methyl-6-(1H-1,2,4-triazol-1-yl)nicotinic acid chloride (0.16 g, 0.73 mmol) was dripped. The resultant was stirred at room temperature for 3 hours. The obtained reaction solution was made acidic with a citric acid aqueous solution, and the product was extracted with ethyl acetate. The obtained organic layer was washed with water, dried with magnesium sulfate and concentrated to obtain the desired product (0.14 g, yield 64%).



1H NMR (CDCl3, 300 MHz)


δ 1.26-1.49 (4H, m), 2.38-2.46 (1H, m), 2.70 (3H, s), 7.85 (1H, d), 8.05 (1H, d), 8.12 (1H, s), 9.23 (1H, s)


Compounds obtained by operating on the basis of the manufacturing method of the compounds of the present invention explained in the synthesis example 1 to 5 are shown in the following table 1 to table 175 together with the compounds synthesized by the synthesis example 1 to 5.


Moreover, the NMR data of physical property values of some compounds are shown in table 176.









TABLE 1









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physical





property


compound


(melting


number
Q
R1
point-ND)


1-1 
Q1a
CH3
NMR


1-2 
Q1a
CH2CH3



1-3 
Q1a
(CH2)2CH3






1-4 
Q1a


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1-5 
Q1a


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1-6 
Q1a


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1-7 
Q1a


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1-8 
Q1a


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1-9 
Q1a


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1-10
Q1a


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1-11
Q1a


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1-12
Q1a
CF3
138-145° C.


1-13
Q1a
CH2CF3



1-14
Q1a
CF2CF3



1-15
Q1a
CH2CH═CH2



1-16
Q1a
CH2C≡CH



1-17
Q1a
C6H5



1-18
Q1a
CH2C6H5



1-19
Q1a
CH2OCH3
NMR


1-20
Q1a
CH2OCH2CH3



1-21
Q1a
CH2O(CH2)2CH3



1-22
Q1a
(CH2)2OCH3



1-23
Q1a
(CH2)3OCH3






1-24
Q1a


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1-25
Q1a


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1-26
Q1a


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1-27
Q1a


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1-28
Q1a
CH2OCH2CF3
NMR


1-29
Q1a
CH2OCF2CHF2



1-30
Q1a
CH2OCH2CF2CF3



1-31
Q1a
CH2OCH2CH═CH2



1-32
Q1a
CH2OCH2CH═CCl2



1-33
Q1a
CH2OCH2CF═CF2



1-34
Q1a
CH2OC2C≡CH



1-35
Q1a
CH2OCH2C≡CCH3



1-36
Q1a
CH2SCH3
1.5755(24)


1-37
Q1a
CH2SCH2CH3



1-38
Q1a
CH2S(CH2)2CH3






1-39
Q1a


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1-40
Q1a


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TABLE 2








physical





property


compound


(melting


number
Q
R1
point-ND)







1-41
Q1a


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1-42
Q1a


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1-43
Q1a
CH2SCH2CF3



1-44
Q1a
CH2SCH2CH═CH2



1-45
Q1a
CH2SCH2C≡CH



1-46
Q1a
CH2SOCH3



1-47
Q1a
CH2SOCH2CH3



1-48
Q1a
CH2SO(CH2)2CH3






1-49
Q1a


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1-50
Q1a


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1-51
Q1a


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1-52
Q1a


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1-53
Q1a
CH2SOCH2CF3



1-54
Q1a
CH2SOCH2CH═CH2



1-55
Q1a
CH2SOCH2C≡CH



1-56
Q1a
CH2SO2CH3
173-174° C.


1-57
Q1a
CH2SO2CH2CH3



1-58
Q1a
CH2SO2(CH2)2CH3






1-59
Q1a


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1-60
Q1a


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1-61
Q1a


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1-62
Q1a


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1-63
Q1a
CH2SO2CH2CF3



1-64
Q1a
CH2SO2CH2CH═CH2



1-65
Q1a
CH2SO2CH2C≡CH



1-66
Q1a
CH2O(CH2)2OCH3
NMR


1-67
Q1a
CH2O(CH2)2OCH2CH3






1-68
Q1a


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1-69
Q1a
CH2O(CH2)2OCH2CF3



1-70
Q1a
CH2O(CH2)2OCH2CH═CH2



1-71
Q1a
CH2O(CH2)2OCH2C≡CH



1-72
Q1a
CH2O(CH2)2SCH3






1-73
Q1a


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1-74
Q1a
CH2O(CH2)2SCH2CF3



1-75
Q1a
CH2O(CH2)2SCH2CH═CH2



1-76
Q1a
CH2O(CH2)2SCH2C≡CH



1-77
Q1a
CH2O(CH2)2SOCH3






1-78
Q1a


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1-79
Q1a
CH2O(CH2)2SOCH2CF3



1-80
Q1a
CH2O(CH2)2SOCH2CH═CH2



















TABLE 3








physical





property


compound


(melting


number
Q
R1
point-ND)







1-81 
Q1a
CH2O(CH2)2SOCH2C≡CH



1-82 
Q1a
CH2O(CH2)2SO2CH3






1-83 
Q1a


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1-84 
Q1a
CH2O(CH2)2SO2CH2CF3



1-85 
Q1a
CH2O(CH2)2SO2CH2CH═CH2



1-86 
Q1a
CH2O(CH2)2SO2CH2C≡CH






1-87 
Q1a


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1-88 
Q1a


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1-89 
Q1a


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1-90 
Q1a


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1-91 
Q1a


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1-92 
Q1a


embedded image








1-93 
Q1a


embedded image








1-94 
Q1a


embedded image








1-95 
Q1a
CH2O(CH2)2NHSO2CH3



1-96 
Q1a
CH2O(CH2)2N(CH3)(SO2CH3)






1-97 
Q1a


embedded image








1-98 
Q1a
CH2O(CH2)2NHSO2CF3



1-99 
Q1a
CH2O(CH2)2NHSO2CHF2



1-100
Q1a
CH2O(CH2)2NHSO2CH2CF3



1-101
Q1a
SCH3



1-102
Q1a
SOCH3



1-103
Q1a
SO2CH3



1-104
Q1a
OCH3



1-105
Q1a
OCH2CH3



1-106
Q1a
O(CH2)2CH3



1-107
Q1a
OCH2CF3



1-108
Q1a
OCF2CF3



1-109
Q1a
O(CH2)2OCH3



1-110
Q1a
NHCH3



1-111
Q1a
NHCH2CH3



1-112
Q1a
N(CH3)2



1-113
Q1a
N(CH2CH3)2



1-114
Q1a
N(CH3)(CH2CH3)



1-115
Q1b
CH3
NMR


1-116
Q1b
CH2CH3



1-117
Q1b
(CH2)3CH3






1-118
Q1b


embedded image








1-119
Q1b


embedded image








1-120
Q1b


embedded image























TABLE 4










physical






property



compound


(melting



number
Q
R1
point-ND)









1-121
Q1b


embedded image










1-122
Q1b


embedded image










1-123
Q1b


embedded image










1-124
Q1b


embedded image










1-125
Q1b


embedded image










1-126
Q1b
CF3




1-127
Q1b
CH2CF3




1-128
Q1b
CF2CF3
1.5395(25)



1-129
Q1b
CH2CH═CH2




1-130
Q1b
CH2C≡CH




1-131
Q1b
C6H5




1-132
Q1b
CH2C6H5




1-133
Q1b
CH2OCH3
1.5685(25)



1-134
Q1b
CH2OCH2CH3




1-135
Q1b
CH2O(CH2)2CH3




1-136
Q1b
(CH2)2OCH3




1-137
Q1b
(CH2)3OCH3








1-138
Q1b


embedded image










1-139
Q1b


embedded image










1-140
Q1b


embedded image










1-141
Q1b


embedded image










1-142
Q1b
CH2OCH2CF3
NMR



1-143
Q1b
CH2OCF2CHF2




1-144
Q1b
CH2OCH2CF2CF3




1-145
Q1b
CH2OCH2CH═CH2




1-146
Q1b
CH2OCH2CH═CCl2




1-147
Q1b
CH2OCH2CF═CF2




1-148
Q1b
CH2OC2C≡CH




1-149
Q1b
CH2OCH2C≡CCH3




1-150
Q1b
CH2SCH3




1-151
Q1b
CH2SCH2CH3




1-152
Q1b
CH2S(CH2)2CH3








1-153
Q1b


embedded image










1-154
Q1b


embedded image










1-155
Q1b


embedded image










1-156
Q1b


embedded image










1-157
Q1b
CH2SCH2CF3




1-158
Q1b
CH2SCH2CH═CH2




1-159
Q1b
CH2SCH2C≡CH




1-160
Q1b
CH2SOCH3




















TABLE 5








physical





property


compound


(melting


number
Q
R1
point-ND)







1-161
Q1b
CH2SOCH2CH3



1-162
Q1b
CH2SO(CH2)2CH3






1-163
Q1b


embedded image








1-164
Q1b


embedded image








1-165
Q1b


embedded image








1-166
Q1b


embedded image








1-167
Q1b
CH2SOCH2CF3



1-168
Q1b
CH2SOCH2CH═CH2



1-169
Q1b
CH2SOCH2C≡CH



1-170
Q1b
CH2SO2CH3



1-171
Q1b
CH2SO2CH2CH3



1-172
Q1b
CH2SO2(CH2)2CH3






1-173
Q1b


embedded image








1-174
Q1b


embedded image








1-175
Q1b


embedded image








1-176
Q1b


embedded image








1-177
Q1b
CH2SO2CH2CF3



1-178
Q1b
CH2SO2CH2CH═CH2



1-179
Q1b
CH2SO2CH2C≡CH



1-180
Q1b
CH2O(CH2)2OCH3



1-181
Q1b
CH2O(CH2)2OCH2CH3






1-182
Q1b


embedded image








1-183
Q1b
CH2O(CH2)2OCH2CF3



1-184
Q1b
CH2O(CH2)2OCH2CH═CH2



1-185
Q1b
CH2O(CH2)2OCH2C≡CH



1-186
Q1b
CH2O(CH2)2SCH3






1-187
Q1b


embedded image








1-188
Q1b
CH2O(CH2)2SCH2CF3



1-189
Q1b
CH2O(CH2)2SCH2CH═CH2



1-190
Q1b
CH2O(CH2)2SCH2C≡CH



1-191
Q1b
CH2O(CH2)2SOCH3






1-192
Q1b


embedded image








1-193
Q1b
CH2O(CH2)2SOCH2CF3



1-194
Q1b
CH2O(CH2)2SOCH2CH═CH2



1-195
Q1b
CH2O(CH2)2SOCH2C≡CH



1-196
Q1b
CH2O(CH2)2SO2CH3






1-197
Q1b


embedded image








1-198
Q1b
CH2O(CH2)2SO2CH2CF3



1-199
Q1b
CH2O(CH2)2SO2CH2CH═CH2



1-200
Q1b
CH2O(CH2)2SO2CH2C≡CH



















TABLE 6








physical





property


compound


(melting


number
Q
R1
point-ND)







1-201
Q1b


embedded image








1-202
Q1b


embedded image








1-203
Q1b


embedded image








1-204
Q1b


embedded image








1-205
Q1b


embedded image








1-206
Q1b


embedded image








1-207
Q1b


embedded image








1-208
Q1b


embedded image








1-209
Q1b
CH2O(CH2)2NHSO2CH3



1-210
Q1b
CH2O(CH2)2N(CH3)(SO2CH3)






1-211
Q1b


embedded image








1-212
Q1b
CH2O(CH2)2NHSO2CF3



1-213
Q1b
CH2O(CH2)2NHSO2CHF2



1-214
Q1b
CH2O(CH2)2NHSO2CH2CF3



1-215
Q1b
SCH3



1-216
Q1b
SOCH3



1-217
Q1b
SO2CH3



1-218
Q1b
OCH3



1-219
Q1b
OCH2CH3



1-220
Q1b
O(CH2)2CH3



1-221
Q1b
OCH2CF3



1-222
Q1b
OCF2CF3



1-223
Q1b
O(CH2)2OCH3



1-224
Q1b
NHCH3



1-225
Q1b
NHCH2CH3



1-226
Q1b
N(CH3)2



1-227
Q1b
N(CH2CH3)2



1-228
Q1b
N(CH3)(CH2CH3)



1-229
Q1c
CH3



1-230
Q1c
CH2CH3



1-231
Q1c
(CH2)2CH3






1-232
Q1c


embedded image








1-233
Q1c


embedded image








1-234
Q1c


embedded image








1-235
Q1c


embedded image








1-236
Q1c


embedded image








1-237
Q1c


embedded image








1-238
Q1c


embedded image








1-239
Q1c


embedded image








1-240
Q1c
CF3





















TABLE 7










physical






property



compound


(melting



number
Q
R1
point-ND)









1-241
Q1c
CH2CF3




1-242
Q1c
CF2CF3




1-243
Q1c
CH2CH═CH2




1-244
Q1c
CH2C≡CH




1-245
Q1c
C6H5




1-246
Q1c
CH2C6H5




1-247
Q1c
CH2OCH3




1-248
Q1c
CH2OCH2CH3




1-249
Q1c
CH2O(CH2)2CH3




1-250
Q1c
(CH2)2OCH3




1-251
Q1c
(CH2)3OCH3








1-252
Q1c


embedded image










1-253
Q1c


embedded image










1-254
Q1c


embedded image










1-255
Q1c


embedded image










1-256
Q1c
CH2OCH2CF3




1-257
Q1c
CH2OCF2CHF2




1-258
Q1c
CH2OCH2CF2CF3




1-259
Q1c
CH2OCH2CH═CH2




1-260
Q1c
CH2OCH2CH═CCl2




1-261
Q1c
CH2OCH2CF═CF2




1-262
Q1c
CH2OC2C≡CH




1-263
Q1c
CH2OCH2C≡CCH3




1-264
Q1c
CH2SCH3




1-265
Q1c
CH2SCH2CH3




1-266
Q1c
CH2S(CH2)2CH3








1-267
Q1c


embedded image










1-268
Q1c


embedded image










1-269
Q1c


embedded image










1-270
Q1c


embedded image










1-271
Q1c
CH2SCH2CF3




1-272
Q1c
CH2SCH2CH═CH2




1-273
Q1c
CH2SCH2C≡CH




1-274
Q1c
CH2SOCH3




1-275
Q1c
CH2SOCH2CH3




1-276
Q1c
CH2SO(CH2)2CH3








1-277
Q1c


embedded image










1-278
Q1c


embedded image










1-279
Q1c


embedded image










1-280
Q1c


embedded image






















TABLE 8








physical





property


compound


(melting


number
Q
R1
point-ND)







1-281
Q1c
CH2SOCH2CF3



1-282
Q1c
CH2SOCH2CH═CH2



1-283
Q1c
CH2SOCH2C≡CH



1-284
Q1c
CH2SO2CH3



1-285
Q1c
CH2SO2CH2CH3



1-286
Q1c
CH2SO2(CH2)2CH3






1-287
Q1c


embedded image








1-288
Q1c


embedded image








1-289
Q1c


embedded image








1-290
Q1c


embedded image








1-291
Q1c
CH2SO2CH2CF3



1-292
Q1c
CH2SO2CH2CH═CH2



1-293
Q1c
CH2SO2CH2C≡CH



1-294
Q1c
CH2O(CH2)2OCH3



1-295
Q1c
CH2O(CH2)2OCH2CH3






1-296
Q1c


embedded image








1-297
Q1c
CH2O(CH2)2OCH2CF3



1-298
Q1c
CH2O(CH2)2OCH2CH═CH2



1-299
Q1c
CH2O(CH2)2OCH2C≡CH



1-300
Q1c
CH2O(CH2)2SCH3






1-301
Q1c


embedded image








1-302
Q1c
CH2O(CH2)2SCH2CF3



1-303
Q1c
CH2O(CH2)2SCH2CH═CH2



1-304
Q1c
CH2O(CH2)2SCH2C≡CH



1-305
Q1c
CH2O(CH2)2SOCH3






1-306
Q1c


embedded image








1-307
Q1c
CH2O(CH2)2SOCH2CF3



1-308
Q1c
CH2O(CH2)2SOCH2CH═CH2



1-309
Q1c
CH2O(CH2)2SOCH2C≡CH



1-310
Q1c
CH2O(CH2)2SO2CH3






1-311
Q1c


embedded image








1-312
Q1c
CH2O(CH2)2SO2CH2CF3



1-313
Q1c
CH2O(CH2)2SO2CH2CH═CH2



1-314
Q1c
CH2O(CH2)2SO2CH2C≡CH






1-315
Q1c


embedded image








1-316
Q1c


embedded image








1-317
Q1c


embedded image








1-318
Q1c


embedded image








1-319
Q1c


embedded image








1-320
Q1c


embedded image





















TABLE 9








physical





property


compound


(melting


number
Q
R1
point-





ND)







1-321
Q1c


embedded image








1-322
Q1c


embedded image








1-323
Q1c
CH2O(CH2)2NHSO2CH3



1-324
Q1c
CH2O(CH2)2N(CH3)(SO2CH3)






1-325
Q1c


embedded image








1-326
Q1c
CH2O(CH2)2NHSO2CF3



1-327
Q1c
CH2O(CH2)2NHSO2CHF2



1-328
Q1c
CH2O(CH2)2NHSO2CH2CF3



1-329
Q1c
SCH3



1-330
Q1c
SOCH3



1-331
Q1c
SO2CH3



1-332
Q1c
OCH3



1-333
Q1c
OCH2CH3



1-334
Q1c
O(CH2)2CH3



1-335
Q1c
OCH2CF3



1-336
Q1c
OCF2CF3



1-337
Q1c
O(CH2)2OCH3



1-338
Q1c
NHCH3



1-339
Q1c
NHCH2CH3



1-340
Q1c
N(CH3)2



1-341
Q1c
N(CH2CH3)2



1-342
Q1c
N(CH3)(CH2CH3)



1-343
Q1d
CH3



1-344
Q1d
CH2CH3



1-345
Q1d
(CH2)2CH3






1-346
Q1d


embedded image








1-347
Q1d


embedded image








1-348
Q1d


embedded image








1-349
Q1d


embedded image








1-350
Q1d


embedded image








1-351
Q1d


embedded image








1-352
Q1d


embedded image








1-353
Q1d


embedded image








1-354
Q1d
CF3



1-355
Q1d
CH2CF3



1-356
Q1d
CF2CF3



1-357
Q1d
CH2CH═CH2



1-358
Q1d
CH2C≡CH



1-359
Q1d
C6H5



1-360
Q1d
CH2C6H5







text missing or illegible when filed




















TABLE 10










physical






property



compound


(melting



number
Q
R1
point-ND)









1-361
Q1d
CH2OCH3




1-362
Q1d
CH2OCH2CH3




1-363
Q1d
CH2O(CH2)2CH3




1-364
Q1d
(CH2)2OCH3




1-365
Q1d
(CH2)3OCH3








1-366
Q1d


embedded image










1-367
Q1d


embedded image










1-368
Q1d


embedded image










1-369
Q1d


embedded image










1-370
Q1d
CH2OCH2CF3




1-371
Q1d
CH2OCF2CHF2




1-372
Q1d
CH2OCH2CF2CF3




1-373
Q1d
CH2OCH2CH═CH2




1-374
Q1d
CH2OCH2CH═CCl2




1-375
Q1d
CH2OCH2CF═CF2




1-376
Q1d
CH2OC2C≡CH




1-377
Q1d
CH2OCH2C≡CCH3




1-378
Q1d
CH2SCH3




1-379
Q1d
CH2SCH2CH3




1-380
Q1d
CH2S(CH2)2CH3








1-381
Q1d


embedded image










1-382
Q1d


embedded image










1-383
Q1d


embedded image










1-384
Q1d


embedded image










1-385
Q1d
CH2SCH2CF3




1-386
Q1d
CH2SCH2CH═CH2




1-387
Q1d
CH2SCH2C≡CH




1-388
Q1d
CH2SOCH3




1-389
Q1d
CH2SOCH2CH3




1-390
Q1d
CH2SO(CH2)2CH3








1-391
Q1d


embedded image










1-392
Q1d


embedded image










1-393
Q1d


embedded image










1-394
Q1d


embedded image










1-395
Q1d
CH2SOCH2CF3




1-396
Q1d
CH2SOCH2CH═CH2




1-397
Q1d
CH2SOCH2C≡CH




1-398
Q1d
CH2SO2CH3




1-399
Q1d
CH2SO2CH2CH3




1-400
Q1d
CH2SO2(CH2)2CH3




















TABLE 11








physical





property


compound


(melting


number
Q
R1
point-ND)







1-401
Q1d


embedded image








1-402
Q1d


embedded image








1-403
Q1d


embedded image








1-404
Q1d


embedded image








1-405
Q1d
CH2SO2CH2CF3



1-406
Q1d
CH2SO2CH2CH═CH2



1-407
Q1d
CH2SO2CH2C≡CH



1-408
Q1d
CH2O(CH2)2OCH3



1-409
Q1d
CH2O(CH2)2OCH2CH3






1-410
Q1d


embedded image








1-411
Q1d
CH2O(CH2)2OCH2CF3



1-412
Q1d
CH2O(CH2)2OCH2CH═CH2



1-413
Q1d
CH2O(CH2)2OCH2C≡CH



1-414
Q1d
CH2O(CH2)2SCH3






1-415
Q1d


embedded image








1-416
Q1d
CH2O(CH2)2SCH2CF3



1-417
Q1d
CH2O(CH2)2SCH2CH═CH2



1-418
Q1d
CH2O(CH2)2SCH2C≡CH



1-419
Q1d
CH2O(CH2)2SOCH3






1-420
Q1d


embedded image








1-421
Q1d
CH2O(CH2)2SOCH2CF3



1-422
Q1d
CH2O(CH2)2SOCH2CH═CH2



1-423
Q1d
CH2O(CH2)2SOCH2C≡CH



1-424
Q1d
CH2O(CH2)2SO2CH3






1-425
Q1d


embedded image








1-426
Q1d
CH2O(CH2)2SO2CH2CF3



1-427
Q1d
CH2O(CH2)2SO2CH2CH═CH2



1-428
Q1d
CH2O(CH2)2SO2CH2C≡CH






1-429
Q1d


embedded image








1-430
Q1d


embedded image








1-431
Q1d


embedded image








1-432
Q1d


embedded image








1-433
Q1d


embedded image








1-434
Q1d


embedded image








1-435
Q1d


embedded image








1-436
Q1d


embedded image








1-437
Q1d
CH2O(CH2)2NHSO2CH3



1-438
Q1d
CH2O(CH2)2N(CH3)(SO2CH3)






1-439
Q1d


embedded image








1-440
Q1d
CH2O(CH2)2NHSO2CF3





















TABLE 12










physical






property



compound


(melting



number
Q
R1
point-ND)









1-441
Q1d
CH2O(CH2)2NHSO2CHF2




1-442
Q1d
CH2O(CH2)2NHSO2CH2CF3




1-443
Q1d
SCH3




1-444
Q1d
SOCH3




1-445
Q1d
SO2CH3




1-446
Q1d
OCH3




1-447
Q1d
OCH2CH3




1-448
Q1d
O(CH2)2CH3




1-449
Q1d
OCH2CF3




1-450
Q1d
OCF2CF3




1-451
Q1d
O(CH2)2OCH3




1-452
Q1d
NHCH3




1-453
Q1d
NHCH2CH3




1-454
Q1d
N(CH3)2




1-455
Q1d
N(CH2CH3)2




1-456
Q1d
N(CH3)(CH2CH3)




1-457
Q1e
CH3
NMR



1-458
Q1e
CH2CH3




1-459
Q1e
(CH2)2CH3








1-460
Q1e


embedded image










1-461
Q1e


embedded image










1-462
Q1e


embedded image










1-463
Q1e


embedded image










1-464
Q1e


embedded image










1-465
Q1e


embedded image










1-466
Q1e


embedded image










1-467
Q1e


embedded image










1-468
Q1e
CF3




1-469
Q1e
CH2CF3




1-470
Q1e
CF2CF3




1-471
Q1e
CH2CH═CH2




1-472
Q1e
CH2C≡CH




1-473
Q1e
C6H5




1-474
Q1e
CH2C6H5




1-475
Q1e
CH2OCH3




1-476
Q1e
CH2OCH2CH3




1-477
Q1e
CH2O(CH2)2CH3




1-478
Q1e
(CH2)2OCH3




1-479
Q1e
(CH2)3OCH3








1-480
Q1e


embedded image























TABLE 13









physical






property






(melting



compound


point-



number
Q
R1
ND)







 
1-481
Q1e


embedded image









1-482
Q1e


embedded image









1-483
Q1e


embedded image









1-484
Q1e
CH2OCH2CF3




1-485
Q1e





1-486
Q1e
CH2OCH2CF2CF3




1-487
Q1e
CH2OCH2CH═CH2




1-488
Q1e
CH2OCH2CH═CCl2




1-489
Q1e
CH2OCH2CF═CF2




1-490
Q1e
CH2OC2C≡CH




1-491
Q1e
CH2OCH2C≡CCH3




1-492
Q1e
CH2SCH3




1-493
Q1e
CH2SCH2CH3




1-494
Q1e
CH2S(CH2)2CH3







1-495
Q1e


embedded image









1-496
Q1e


embedded image









1-497
Q1e


embedded image









1-498
Q1e


embedded image









1-499
Q1e
CH2SCH2CF3




1-500
Q1e
CH2SCH2CH═CH2




1-501
Q1e
CH2SCH2C≡CH




1-502
Q1e
CH2SOCH3




1-503
Q1e
CH2SOCH2CH3




1-504
Q1e
CH2SO(CH2)2CH3







1-505
Q1e


embedded image









1-506
Q1e


embedded image









1-507
Q1e


embedded image









1-508
Q1e


embedded image









1-509
Q1e
CH2SOCH2CF3




1-510
Q1e
CH2SOCH2CH═CH2




1-511
Q1e
CH2SOCH2C≡CH




1-512
Q1e
CH2SO2CH3




1-513
Q1e
CH2SO2CH2CH3




1-514
Q1e
CH2SO2(CH2)2CH3







1-515
Q1e


embedded image









1-516
Q1e


embedded image









1-517
Q1e


embedded image









1-518
Q1e


embedded image









1-519
Q1e
CH2SO2CH2CF3




1-520
Q1e
CH2SO2CH2CH═CH2



















TABLE 14








physical





property


com-


(melting


pound


point-


number
Q
R1
ND)







1-521
Q1e
CH2SO2CH2C≡CH



1-522
Q1e
CH2O(CH2)2OCH3



1-523
Q1e
CH2O(CH2)2OCH2CH3






1-524
Q1e


embedded image








1-525
Q1e
CH2O(CH2)2OCH2CF3



1-526
Q1e
CH2O(CH2)2OCH2CH═CH2



1-527
Q1e
CH2O(CH2)2OCH2C≡CH



1-528
Q1e
CH2O(CH2)2SCH3






1-529
Q1e


embedded image








1-530
Q1e
CH2O(CH2)2SCH2CF3



1-531
Q1e
CH2O(CH2)2SCH2CH═CH2



1-532
Q1e
CH2O(CH2)2SCH2C≡CH



1-533
Q1e
CH2O(CH2)2SOCH3






1-534
Q1e


embedded image








1-535
Q1e
CH2O(CH2)2SOCH2CF3



1-536
Q1e
CH2O(CH2)2SOCH2CH═CH2



1-537
Q1e
CH2O(CH2)2SOCH2C≡CH



1-538
Q1e
CH2O(CH2)2SO2CH3






1-539
Q1e


embedded image








1-540
Q1e
CH2O(CH2)2SO2CH2CF3



1-541
Q1e
CH2O(CH2)2SO2CH2CH═CH2



1-542
Q1e
CH2O(CH2)2SO2CH2C≡CH






1-543
Q1e


embedded image








1-544
Q1e


embedded image








1-545
Q1e


embedded image








1-546
Q1e


embedded image








1-547
Q1e


embedded image








1-548
Q1e


embedded image








1-549
Q1e


embedded image








1-550
Q1e


embedded image








1-551
Q1e
CH2O(CH2)2NHSO2CH3



1-552
Q1e
CH2O(CH2)2N(CH3)(SO2CH3)






1-553
Q1e


embedded image








1-554
Q1e
CH2O(CH2)2NHSO2CF3



1-555
Q1e
CH2O(CH2)2NHSO2CHF2



1-556
Q1e
CH2O(CH2)2NHSO2CH2CF3



1-557
Q1e
SCH3



1-558
Q1e
SOCH3



1-559
Q1e
SO2CH3



1-560
Q1e
OCH3




















TABLE 15









physical






property






(melting



compound


point-



number
Q
R1
ND)







 
1-561
Q1e
OCH2CH3




1-562
Q1e
O(CH2)2CH3




1-563
Q1e
OCH2CF3




1-564
Q1e
OCF2CF3




1-565
Q1e
O(CH2)2OCH3




1-566
Q1e
NHCH3




1-567
Q1e
NHCH2CH3




1-568
Q1e
N(CH3)2




1-569
Q1e
N(CH2CH3)2




1-570
Q1e
N(CH3)(CH2CH3)




1-571
Q1f
CH3




1-572
Q1f
CH2CH3




1-573
Q1f
(CH2)2CH3







1-574
Q1f


embedded image









1-575
Q1f


embedded image









1-576
Q1f


embedded image









1-577
Q1f


embedded image









1-578
Q1f


embedded image









1-579
Q1f


embedded image









1-580
Q1f


embedded image









1-581
Q1f


embedded image









1-582
Q1f
CF3




1-583
Q1f
CH2CF3




1-584
Q1f
CF2CF3




1-585
Q1f
CH2CH═CH2




1-586
Q1f
CH2C≡CH




1-587
Q1f
C6H5




1-588
Q1f
CH2C6H5




1-589
Q1f
CH2OCH3




1-590
Q1f
CH2OCH2CH3




1-591
Q1f
CH2O(CH2)2CH3




1-592
Q1f
(CH2)2OCH3




1-593
Q1f
(CH2)3OCH3







1-594
Q1f


embedded image









1-595
Q1f


embedded image









1-596
Q1f


embedded image









1-597
Q1f


embedded image









1-598
Q1f
CH2OCH2CF3




1-599
Q1f
CH2OCF2CHF2




1-600
Q1f
CH2OCH2CF2CF3



















TABLE 16








physical





property


compound


(melting


number

text missing or illegible when filed

R1
point-ND)







1-601

text missing or illegible when filed 1f
CH2OCH2CH═CH2



1-602

text missing or illegible when filed 1f
CH2OCH2CH═CCl2



1-603

text missing or illegible when filed 1f
CH2OCH2CF═CFtext missing or illegible when filed



1-604

text missing or illegible when filed 1f
CHtext missing or illegible when filed OC2Ctext missing or illegible when filed CH



1-605

text missing or illegible when filed 1f
CH2OCH2Ctext missing or illegible when filed CCH3



1-606

text missing or illegible when filed 1f
CH2SCH3



1-607

text missing or illegible when filed 1f
CH2SCH2CH3



1-608

text missing or illegible when filed 1f
CH2S(CH2)2CH3






1-609

text missing or illegible when filed 1f


embedded image








1-610

text missing or illegible when filed 1f


embedded image








1-611

text missing or illegible when filed 1f


embedded image








1-612

text missing or illegible when filed 1f


embedded image








1-613

text missing or illegible when filed 1f
CH2SCH2CF3



1-614

text missing or illegible when filed 1f
CH2SCH2CH═CHtext missing or illegible when filed



1-615

text missing or illegible when filed 1f
CH2SCH2C═CH



1-616

text missing or illegible when filed 1f
CH2SOCH3



1-617

text missing or illegible when filed 1f
CH2SOCH2CH3



1-618

text missing or illegible when filed 1f
CH2SO(CH2)2CH3






1-619

text missing or illegible when filed 1f


embedded image








1-620

text missing or illegible when filed 1f


embedded image








1-621

text missing or illegible when filed 1f


embedded image








1-622

text missing or illegible when filed 1f


embedded image








1-623

text missing or illegible when filed 1f
CH2SOCH2CF3



1-624

text missing or illegible when filed 1f
CH2SOCH2CH═CH2



1-625

text missing or illegible when filed 1f
CH2SOCH2C═CH



1-626

text missing or illegible when filed 1f
CH2SO2CH3



1-627

text missing or illegible when filed 1f
CH2SO2CH2CH3



1-628

text missing or illegible when filed 1f
CH2SOtext missing or illegible when filed (CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed






1-629

text missing or illegible when filed 1f


embedded image








1-630

text missing or illegible when filed 1f


embedded image








1-631

text missing or illegible when filed 1f


embedded image








1-632

text missing or illegible when filed 1f


embedded image








1-633

text missing or illegible when filed 1f
CH2SO2CH2CF3



1-634

text missing or illegible when filed 1f
CH2SO2CH2CH═CHtext missing or illegible when filed



1-635

text missing or illegible when filed 1f
CH2SO2CH2C═CH



1-636

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



1-637

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3






1-638

text missing or illegible when filed 1f


embedded image








1-639

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



1-640

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH═CHtext missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 17








physical





property


com-


(melting


pound


point-


number

text missing or illegible when filed

R1
ND)







1-641

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed ═CH



1-642

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed






1-643

text missing or illegible when filed 1f


embedded image








1-644

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CF3



1-645

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CH═CHtext missing or illegible when filed



1-646

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed C═CH



1-647

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3






1-648

text missing or illegible when filed 1f


embedded image








1-649

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CF3



1-650

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CH═CHtext missing or illegible when filed



1-651

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed C═CH



1-652

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CH3






1-653

text missing or illegible when filed 1f


embedded image








1-654

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CH2CF3



1-655

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CH═CHtext missing or illegible when filed



1-656

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed C═CH






1-657

text missing or illegible when filed 1f


embedded image








1-658

text missing or illegible when filed 1f


embedded image








1-659

text missing or illegible when filed 1f


embedded image








1-660

text missing or illegible when filed 1f


embedded image








1-661

text missing or illegible when filed 1f


embedded image








1-662

text missing or illegible when filed 1f


embedded image








1-663

text missing or illegible when filed 1f


embedded image








1-664

text missing or illegible when filed 1f


embedded image








1-665

text missing or illegible when filed 1f
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



1-666

text missing or illegible when filed 1f
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SO2CH3)






1-667

text missing or illegible when filed 1f


embedded image








1-668

text missing or illegible when filed 1f
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CF3



1-669

text missing or illegible when filed 1f
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHFtext missing or illegible when filed



1-670

text missing or illegible when filed 1f
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHtext missing or illegible when filed CF3



1-671

text missing or illegible when filed 1f
SCH3



1-672

text missing or illegible when filed 1f
SOCH3



1-673

text missing or illegible when filed 1f
SO2CH3



1-674

text missing or illegible when filed 1f
OCH3



1-675

text missing or illegible when filed 1f
OCH2CH3



1-676

text missing or illegible when filed 1f
O(CHtext missing or illegible when filed )text missing or illegible when filed CH3



1-677

text missing or illegible when filed 1f
OCH2CF3



1-678

text missing or illegible when filed 1f
OCF2CF3



1-679

text missing or illegible when filed 1f
O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed



1-680

text missing or illegible when filed 1f
NHCH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 18








physical





property


compound


(melting


number

text missing or illegible when filed

R1
point-ND)







1-681

text missing or illegible when filed 1f
NHCH2CH3



1-682

text missing or illegible when filed 1f
N(CHtext missing or illegible when filed )text missing or illegible when filed



1-683

text missing or illegible when filed 1f
N(CHtext missing or illegible when filed CHtext missing or illegible when filed )text missing or illegible when filed



1-684

text missing or illegible when filed 1f
N(CHtext missing or illegible when filed )(CHtext missing or illegible when filed CH3)



1-685

text missing or illegible when filed 1g
CH3
NMR


1-686

text missing or illegible when filed 1g
CH2CH3



1-687

text missing or illegible when filed 1g
(CHtext missing or illegible when filed )text missing or illegible when filed CH3






1-688

text missing or illegible when filed 1g


embedded image








1-689

text missing or illegible when filed 1g


embedded image








1-690

text missing or illegible when filed 1g


embedded image








1-691

text missing or illegible when filed 1g


embedded image








1-692

text missing or illegible when filed 1g


embedded image








1-693

text missing or illegible when filed 1g


embedded image








1-694

text missing or illegible when filed 1g


embedded image








1-695

text missing or illegible when filed 1g


embedded image








1-696

text missing or illegible when filed 1g
CF3



1-697

text missing or illegible when filed 1g
CH2CF3



1-698

text missing or illegible when filed 1g
CF2CF3



1-699

text missing or illegible when filed 1g
CH2CH═CHtext missing or illegible when filed



1-700

text missing or illegible when filed 1g
CH2C═CH



1-701

text missing or illegible when filed 1g
Ctext missing or illegible when filed Htext missing or illegible when filed



1-702

text missing or illegible when filed 1g
CH2C6H5



1-703

text missing or illegible when filed 1g
CH2OCH3
114-120° C.


1-704

text missing or illegible when filed 1g
CH2OCH2CH3



1-705

text missing or illegible when filed 1g
CH2O(CH2)text missing or illegible when filed CHtext missing or illegible when filed



1-706

text missing or illegible when filed 1g
(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



1-707

text missing or illegible when filed 1g
(CHtext missing or illegible when filed )text missing or illegible when filed OCH3






1-708

text missing or illegible when filed 1g


embedded image








1-709

text missing or illegible when filed 1g


embedded image








1-710

text missing or illegible when filed 1g


embedded image








1-711

text missing or illegible when filed 1g


embedded image








1-712

text missing or illegible when filed 1g
CH2OCH2CF3
NMR


1-713

text missing or illegible when filed 1g
CH2OCFtext missing or illegible when filed CHFtext missing or illegible when filed



1-714

text missing or illegible when filed 1g
CH2OCH2CF2CF3



1-715

text missing or illegible when filed 1g
CH2OCHtext missing or illegible when filed CH═CHtext missing or illegible when filed



1-716

text missing or illegible when filed 1g
CH2OCH2CH═CCltext missing or illegible when filed



1-717

text missing or illegible when filed 1g
CH2OCH2CF═CFtext missing or illegible when filed



1-718

text missing or illegible when filed 1g
CH2OCtext missing or illegible when filed Ctext missing or illegible when filed CH



1-719

text missing or illegible when filed 1g
CH2OCH2Ctext missing or illegible when filed CCHtext missing or illegible when filed



1-720

text missing or illegible when filed 1g
CH2SCH3






text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 19










physical






property






(melting



compound


point-



number

text missing or illegible when filed

R1
ND)









1-721

text missing or illegible when filed 1g
CH2SCH2CH3




1-722

text missing or illegible when filed 1g
CH2S(CH3)2CH3








1-723

text missing or illegible when filed 1g


embedded image










1-724

text missing or illegible when filed 1g


embedded image










1-725

text missing or illegible when filed 1g


embedded image










1-726

text missing or illegible when filed 1g


embedded image










1-727

text missing or illegible when filed 1g
CH2SCH2CF3




1-728

text missing or illegible when filed 1g
CH2SCH2CH═CHtext missing or illegible when filed




1-729

text missing or illegible when filed 1g
CH2SCH2C═CH




1-730

text missing or illegible when filed 1g
CH2SOCH3




1-731

text missing or illegible when filed 1g
CH2SOCH2CH3




1-732

text missing or illegible when filed 1g
CH2SO(CHtext missing or illegible when filed )text missing or illegible when filed CH3








1-733

text missing or illegible when filed 1g


embedded image










1-734

text missing or illegible when filed 1g


embedded image










1-735

text missing or illegible when filed 1g


embedded image










1-736

text missing or illegible when filed 1g


embedded image










1-737

text missing or illegible when filed 1g
CH2SOCH2CF3




1-738

text missing or illegible when filed 1g
CH2SOCH2CH═CHtext missing or illegible when filed




1-739

text missing or illegible when filed 1g
CH2SOCH2C═CH




1-740

text missing or illegible when filed 1g
CH2SO2CH3




1-741

text missing or illegible when filed 1g
CH2SO2CH2CH3




1-742

text missing or illegible when filed 1g
CH2SO2(CHtext missing or illegible when filed )text missing or illegible when filed CH3








1-743

text missing or illegible when filed 1g


embedded image










1-744

text missing or illegible when filed 1g


embedded image










1-745

text missing or illegible when filed 1g


embedded image










1-746

text missing or illegible when filed 1g


embedded image










1-747

text missing or illegible when filed 1g
CH2SO2CH2CF3




1-748

text missing or illegible when filed 1g
CH2SO2CH2CH═CHtext missing or illegible when filed




1-749

text missing or illegible when filed 1g
CH2SO2CH2C═CH




1-750

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




1-751

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3








1-752

text missing or illegible when filed 1g


embedded image










1-753

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




1-754

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH═CH2




1-755

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2Ctext missing or illegible when filed H




1-756

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3








1-757

text missing or illegible when filed 1g


embedded image










1-758

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3




1-759

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CH═CH2




1-760

text missing or illegible when filed 1g
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2C═CH








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 20








physical





property


compound


(melting


number
Q
R1
point-ND)







1-761
Q1g
CH2O(CH2)2SOCH3






1-762
Q1g


embedded image








1-763
Q1g
CH2O(CH2)2SOCH2CF3



1-764
Q1g
CH2O(CH2)2SOCH2CH═CH2



1-765
Q1g
CH2O(CH2)2SOCH2C≡CH



1-766
Q1g
CH2O(CH2)2SO2CH3






1-767
Q1g


embedded image








1-768
Q1g
CH2O(CH2)2SO2CH2CF3



1-769
Q1g
CH2O(CH2)2SO2CH2CH═CH2



1-770
Q1g
CH2O(CH2)2SO2CH2C≡CH






1-771
Q1g


embedded image








1-772
Q1g


embedded image








1-773
Q1g


embedded image








1-774
Q1g


embedded image








1-775
Q1g


embedded image








1-776
Q1g


embedded image








1-777
Q1g


embedded image








1-778
Q1g


embedded image








1-779
Q1g
CH2O(CH2)2NHSO2CH3



1-780
Q1g
CH2O(CH2)2N(CH3)(SO2CH3)






1-781
Q1g


embedded image








1-782
Q1g
CH2O(CH2)2NHSO2CF3



1-783
Q1g
CH2O(CH2)2NHSO2CHF2



1-784
Q1g
CH2O(CH2)2NHSO2CH2CF3



1-785
Q1g
SCH3



1-786
Q1g
SOCH3



1-787
Q1g
SO2CH3



1-788
Q1g
OCH3



1-789
Q1g
OCH2CH3



1-790
Q1g
O(CH2)2CH3



1-791
Q1g
OCH2CF3



1-792
Q1g
OCF2CF3



1-793
Q1g
O(CH2)2OCH3



1-794
Q1g
NHCH3



1-795
Q1g
NHCH2CH3



1-796
Q1g
N(CH3)2



1-797
Q1g
N(CH2CH3)2



1-798
Q1g
N(CH3)(CH2CH3)



1-799
Q1h
CH3
NMR


1-800
Q1h
CH2CH3




















TABLE 21









physical






property






(melting



compound


point-



number
Q
R1
ND)







 
1-801
Q1h
(CH2)2CH3







1-802
Q1h


embedded image









1-803
Q1h


embedded image









1-804
Q1h


embedded image









1-805
Q1h


embedded image









1-806
Q1h


embedded image









1-807
Q1h


embedded image









1-808
Q1h


embedded image









1-809
Q1h


embedded image









1-810
Q1h
CF3
1.5495






(25)



1-811
Q1h
CH2CF3




1-812
Q1h
CF2CF3




1-813
Q1h
CH2CH═CH2




1-814
Q1h
CH2C≡CH




1-815
Q1h
C6H5




1-816
Q1h
CH2C6H5




1-817
Q1h
CH2OCH3
1.5773






(25)



1-818
Q1h
CH2OCH2CH3




1-819
Q1h
CH2O(CH2)2CH3




1-820
Q1h
(CH2)2OCH3




1-821
Q1h
(CH2)3OCH3







1-822
Q1h


embedded image









1-823
Q1h


embedded image









1-824
Q1h


embedded image









1-825
Q1h


embedded image









1-826
Q1h
CH2OCH2CF3
NMR



1-827
Q1h
CH2OCF2CHF2




1-828
Q1h
CH2OCH2CF2CF3




1-829
Q1h
CH2OCH2CH═CH2




1-830
Q1h
CH2OCH2CH═CCl2




1-831
Q1h
CH2OCH2CF═CF2




1-832
Q1h
CH2OC2C≡CH




1-833
Q1h
CH2OCH2C≡CCH3




1-834
Q1h
CH2SCH3




1-835
Q1h
CH2SCH2CH3




1-836
Q1h
CH2S(CH2)2CH3







1-837
Q1h


embedded image









1-838
Q1h


embedded image









1-839
Q1h


embedded image









1-840
Q1h


embedded image






















TABLE 22









physical






property






(melting



compound


point-



number
Q
R1
ND)







 
1-841
Q1h
CH2SCH2CF3




1-842
Q1h
CH2SCH2CH═CH2




1-843
Q1h
CH2SCH2C≡CH




1-844
Q1h
CH2SOCH3




1-845
Q1h
CH2SOCH2CH3




1-846
Q1h
CH2SO(CH2)2CH3







1-847
Q1h


embedded image









1-848
Q1h


embedded image









1-849
Q1h


embedded image









1-850
Q1h


embedded image









1-851
Q1h
CH2SOCH2CF3




1-852
Q1h
CH2SOCH2CH═CH2




1-853
Q1h
CH2SOCH2C≡CH




1-854
Q1h
CH2SO2CH3




1-855
Q1h
CH2SO2CH2CH3




1-856
Q1h
CH2SO2(CH2)2CH3







1-857
Q1h


embedded image









1-858
Q1h


embedded image









1-859
Q1h


embedded image









1-860
Q1h


embedded image









1-861
Q1h
CH2SO2CH2CF3




1-862
Q1h
CH2SO2CH2CH═CH2




1-863
Q1h
CH2SO2CH2C≡CH




1-864
Q1h
CH2O(CH2)2OCH3




1-865
Q1h
CH2O(CH2)2OCH2CH3







1-866
Q1h


embedded image









1-867
Q1h
CH2O(CH2)2OCH2CF3




1-868
Q1h
CH2O(CH2)2OCH2CH═CH2




1-869
Q1h
CH2O(CH2)2OCH2C≡CH




1-870
Q1h
CH2O(CH2)2SCH3







1-871
Q1h


embedded image









1-872
Q1h
CH2O(CH2)2SCH2CF3




1-873
Q1h
CH2O(CH2)2SCH2CH═CH2




1-874
Q1h
CH2O(CH2)2SCH2C≡CH




1-875
Q1h
CH2O(CH2)2SOCH3







1-876
Q1h


embedded image









1-877
Q1h
CH2O(CH2)2SOCH2CF3




1-878
Q1h
CH2O(CH2)2SOCH2CH═CH2




1-879
Q1h
CH2O(CH2)2SOCH2C≡CH




1-880
Q1h
CH2O(CH2)2SO2CH3



















TABLE 23








physical





property


com-


(melting


pound


point-


number
Q
R1
ND)







1-881
Q1h


embedded image








1-882
Q1h
CH2O(CH2)2SO2CH2CF3



1-883
Q1h
CH2O(CH2)2SO2CH2CH═CH2



1-884
Q1h
CH2O(CH2)2SO2CH2C≡CH






1-885
Q1h


embedded image








1-886
Q1h


embedded image








1-887
Q1h


embedded image








1-888
Q1h


embedded image








1-889
Q1h


embedded image








1-890
Q1h


embedded image








1-891
Q1h


embedded image








1-892
Q1h


embedded image








1-893
Q1h
CH2O(CH2)2NHSO2CH3



1-894
Q1h
CH2O(CH2)2N(CH3)(SO2CH3)






1-895
Q1h


embedded image








1-896
Q1h
CH2O(CH2)2NHSO2CF3



1-897
Q1h
CH2O(CH2)2NHSO2CHF2



1-898
Q1h
CH2O(CH2)2NHSO2CH2CF3



1-899
Q1h
SCH3



1-900
Q1h
SOCH3



1-901
Q1h
SO2CH3



1-902
Q1h
OCH3



1-903
Q1h
OCH2CH3



1-904
Q1h
O(CH2)2CH3



1-905
Q1h
OCH2CF3



1-906
Q1h
OCF2CF3



1-907
Q1h
O(CH2)2OCH3



1-908
Q1h
NHCH3



1-909
Q1h
NCH2CH3



1-910
Q1h
N(CH3)2



1-911
Q1h
N(CH2CH3)2



1-912
Q1h
N(CH3)(CH2CH3)



1-913
Q1i
CH3
NMR


1-914
Q1i
CH2CH3



1-915
Q1i
(CH2)2CH3






1-916
Q1i


embedded image








1-917
Q1i


embedded image








1-918
Q1i


embedded image








1-919
Q1i


embedded image








1-920
Q1i


embedded image























TABLE 24










physical






property



compound


(melting



number
Q
R1
point-ND)









1-921
Q1i


embedded image










1-922
Q1i


embedded image










1-923
Q1i


embedded image










1-924
Q1i
CF3




1-925
Q1i
CH2CF3




1-926
Q1i
CF2CF3




1-927
Q1i
CH2CH═CH2




1-928
Q1i
CH2C≡CH




1-929
Q1i
C6H5




1-930
Q1i
CH2C6H5




1-931
Q1i
CH2OCH3




1-932
Q1i
CH2OCH2CH3




1-933
Q1i
CH2O(CH2)2CH3




1-934
Q1i
(CH2)2OCH3




1-935
Q1i
(CH2)3OCH3








1-936
Q1i


embedded image










1-937
Q1i


embedded image










1-938
Q1i


embedded image










1-939
Q1i


embedded image










1-940
Q1i
CH2OCH2CF3




1-941
Q1i
CH2OCF2CHF2




1-942
Q1i
CH2OCH2CF2CF3




1-943
Q1i
CH2OCH2CH═CH2




1-944
Q1i
CH2OCH2CH═CCl2




1-945
Q1i
CH2OCH2CF═CF2




1-946
Q1i
CH2OC2C≡CH




1-947
Q1i
CH2OCH2C≡CCH3




1-948
Q1i
CH2SCH3




1-949
Q1i
CH2SCH2CH3




1-950
Q1i
CH2S(CH2)2CH3








1-951
Q1i


embedded image










1-952
Q1i


embedded image










1-953
Q1i


embedded image










1-954
Q1i


embedded image










1-955
Q1i
CH2SCH2CF3




1-956
Q1i
CH2SCH2CH═CH2




1-957
Q1i
CH2SCH2C≡CH




1-958
Q1i
CH2SOCH3




1-959
Q1i
CH2SOCH2CH3




1-960
Q1i
CH2SO(CH2)2CH3





















TABLE 25









physical






property



compound


(melting



number
Q
R1
point-ND)








1-961
Q1i


embedded image









1-962
Q1i


embedded image









1-963
Q1i


embedded image









1-964
Q1i


embedded image









1-965
Q1i
CH2SOCH2CF3




1-966
Q1i
CH2SOCH2CH═CH2




1-967
Q1i
CH2SOCH2C≡CH




1-968
Q1i
CH2SO2CH3




1-969
Q1i
CH2SO2CH2CH3




1-970
Q1i
CH2SO2(CH2)2CH3







1-971
Q1i


embedded image









1-972
Q1i


embedded image









1-973
Q1i


embedded image









1-974
Q1i


embedded image









1-975
Q1i
CH2SO2CH2CF3




1-976
Q1i
CH2SO2CH2CH═CH2




1-977
Q1i
CH2CO2CH2C≡CH




1-978
Q1i
CH2O(CH2)2OCH3




1-979
Q1i
CH2O(CH2)2OCH2CH3







1-980
Q1i


embedded image









1-981
Q1i
CH2O(CH2)2OCH2CF3




1-982
Q1i
CH2O(CH2)2OCH2CH═CH2




1-983
Q1i
CH2O(CH2)2OCH2C≡CH




1-984
Q1i
CH2O(CH2)2SCH3







1-985
Q1i


embedded image









1-986
Q1i
CH2O(CH2)2SCH2CF3




1-987
Q1i
CH2O(CH2)2SCH2CH═CH2




1-988
Q1i
CH2O(CH2)2SCH2C≡CH




1-989
Q1i
CH2O(CH2)2SOCH3







1-990
Q1i


embedded image









1-991
Q1i
CH2O(CH2)2SOCH2CF3




1-992
Q1i
CH2O(CH2)2SOCH2CH═CH2




1-993
Q1i
CH2O(CH2)2SOCH2C≡CH




1-994
Q1i
CH2O(CH2)2SO2CH3







1-995
Q1i


embedded image









1-996
Q1i
CH2O(CH2)2SO2CH2CF3




1-997
Q1i
CH2O(CH2)2SO2CH2CH═CH2




1-998
Q1i
CH2O(CH2)2SO2CH2C≡CH







1-999
Q1i


embedded image









1-1000
Q1i


embedded image





















TABLE 26








physical





property


compound


(melting


number
Q
R1
point-ND)







1-1001
Q1i


embedded image








1-1002
Q1i


embedded image








1-1003
Q1i


embedded image








1-1004
Q1i


embedded image








1-1005
Q1i


embedded image








1-1006
Q1i


embedded image








1-1007
Q1i
CH2O(CH2)2NHSO2CH3



1-1008
Q1i
CH2O(CH2)2N(CH3)(SO2CH3)






1-1009
Q1i


embedded image








1-1010
Q1i
CH2O(CH2)2NHSO2CF3



1-1011
Q1i
CH2O(CH2)2NHSO2CHF2



1-1012
Q1i
CH2O(CH2)2NHSO2CH2CF3



1-1013
Q1i
SCH3



1-1014
Q1i
SOCH3



1-1015
Q1i
SO2CH3



1-1016
Q1i
OCH3



1-1017
Q1i
OCH2CH3



1-1018
Q1i
O(CH2)2CH3



1-1019
Q1i
OCH2CF3



1-1020
Q1i
OCF2CF3



1-1021
Q1i
O(CH2)2OCH3



1-1022
Q1i
NHCH3



1-1023
Q1i
NHCH2CH3



1-1024
Q1i
N(CH3)2



1-1025
Q1i
N(CH2CH3)2



1-1026
Q1i
N(CH3)(CH2CH3)


















TABLE 27









embedded image




embedded image




embedded image
















embedded image




embedded image




embedded image














embedded image


















physical





property


compound


(melting


number
Q
R1
point-ND)





2-1
Q2a
CH3
NMR


2-2
Q2a
CH2CH3



2-3
Q2a
(CH2)2CH3






2-4
Q2a


embedded image








2-5
Q2a


embedded image








2-6
Q2a


embedded image








2-7
Q2a


embedded image








2-8
Q2a


embedded image








2-9
Q2a


embedded image








2-10
Q2a


embedded image








2-11
Q2a


embedded image








2-12
Q2a
CF3
174-178° C.


2-13
Q2a
CH2CF3



2-14
Q2a
CF2CF3



2-15
Q2a
CH2CH═CH2



2-16
Q2a
CH2C≡CH



2-17
Q2a
C6H5



2-18
Q2a
CH2C6H5



2-19
Q2a
CH2OCH3



2-20
Q2a
CH2OCH2CH3



2-21
Q2a
CH2O(CH2)2CH3



2-22
Q2a
(CH2)2OCH3



2-23
Q2a
(CH2)3OCH3






2-24
Q2a


embedded image








2-25
Q2a


embedded image








2-26
Q2a


embedded image








2-27
Q2a


embedded image








2-28
Q2a
CH2OCH2CF3
NMR


2-29
Q2a
CH2OCF2CHF2



2-30
Q2a
CH2OCH2CF2CF3



2-31
Q2a
CH2OCH2CH═CH2



2-32
Q2a
CH2OCH2CH═CCl2



2-33
Q2a
CH2OCH2CF═CF2



2-34
Q2a
CH2OC2C═CH



2-35
Q2a
CH2OCH2C≡CCH3



2-36
Q2a
CH2SCH3



2-37
Q2a
CH2SCH2CH3



2-38
Q2a
CH2S(CH2)2CH3






2-39
Q2a


embedded image








2-40
Q2a


embedded image





















TABLE 28








physical





property





(melting


compound


point-


number

text missing or illegible when filed

Rtext missing or illegible when filed
ND)







2-41

text missing or illegible when filed 2a


embedded image








2-42

text missing or illegible when filed 2a


embedded image








2-43

text missing or illegible when filed 2a
CHtext missing or illegible when filed SCH2CF3



2-44

text missing or illegible when filed 2a
CH2SCH2CH═CHtext missing or illegible when filed



2-45

text missing or illegible when filed 2a
CH2SCHtext missing or illegible when filed C≡CH



2-46

text missing or illegible when filed 2a
CH2SOCH3



2-47

text missing or illegible when filed 2a
CH2SOCH2CH3



2-48

text missing or illegible when filed 2a
CH2SO(CHtext missing or illegible when filed )text missing or illegible when filed CH3






2-49

text missing or illegible when filed 2a


embedded image








2-50

text missing or illegible when filed 2a


embedded image








2-51

text missing or illegible when filed 2a


embedded image








2-52

text missing or illegible when filed 2a


embedded image








2-53

text missing or illegible when filed 2a
CH2SOCH2CF3



2-54

text missing or illegible when filed 2a
CH2SOCH2CH═CH2



2-55

text missing or illegible when filed 2a
CH2SOCH2C≡CH



2-56

text missing or illegible when filed 2a
CH2SO2CH3



2-57

text missing or illegible when filed 2a
CH2SO2CH2CH3



2-58

text missing or illegible when filed 2a
CH2SO2(CHtext missing or illegible when filed )text missing or illegible when filed CH3






2-59

text missing or illegible when filed 2a


embedded image








2-60

text missing or illegible when filed 2a


embedded image








2-61

text missing or illegible when filed 2a


embedded image








2-62

text missing or illegible when filed 2a


embedded image








2-63

text missing or illegible when filed 2a
CH2SO2CH2CF3



2-64

text missing or illegible when filed 2a
CH2SO2CH2CH═CHtext missing or illegible when filed



2-65

text missing or illegible when filed 2a
CH2SO2CH2C═CH



2-66

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



2-67

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3






2-68

text missing or illegible when filed 2a


embedded image








2-69

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



2-70

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH═CHtext missing or illegible when filed



2-71

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2C═CH



2-72

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3






2-73

text missing or illegible when filed 2a


embedded image








2-74

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



2-75

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CH═CHtext missing or illegible when filed



2-76

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2C═CH



2-77

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3






2-78

text missing or illegible when filed 2a


embedded image








2-79

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



2-80

text missing or illegible when filed 2a
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CH═CH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 29








physical





property


compound


(melting


number
Q
R1
point-ND)







2-81 
Q2a
CH2O(CH2)2SOCH2C≡CH



2-82 
Q2a
CH2O(CH2)2SO2CH3






2-83 
Q2a


embedded image








2-84 
Q2a
CH2O(CH2)2SO2CH2CF3



2-85 
Q2a
CH2O(CH2)2SO2CH2CH═CH2



2-86 
Q2a
CH2O(CH2)2SO2CH2C≡CH






2-87 
Q2a


embedded image








2-88 
Q2a


embedded image








2-89 
Q2a


embedded image








2-90 
Q2a


embedded image








2-91 
Q2a


embedded image








2-92 
Q2a


embedded image








2-93 
Q2a


embedded image








2-94 
Q2a


embedded image








2-95 
Q2a
CH2O(CH2)2NHSO2CH3



2-96 
Q2a
CH2O(CH2)2N(CH3)(SO2CH3)






2-97 
Q2a


embedded image








2-98 
Q2a
CH2O(CH2)2NHSO2CF3



2-99 
Q2a
CH2O(CH2)2NHSO2CHF2



2-100
Q2a
CH2O(CH2)2NHSO2CH2CF3



2-101
Q2a
SCH3



2-102
Q2a
SOCH3



2-103
Q2a
SO2CH3



2-104
Q2a
OCH3



2-105
Q2a
OCH2CH3



2-106
Q2a
O(CH2)2CH3



2-107
Q2a
OCH2CF3



2-108
Q2a
OCF2CF3



2-109
Q2a
O(CH2)2OCH3



2-110
Q2a
NHCH3



2-111
Q2a
NHCH2CH3



2-112
Q2a
N(CH3)2



2-113
Q2a
N(CH2CH3)2



2-114
Q2a
N(CH3)(CH2CH3)



2-115
Q2b
CH3



2-116
Q2b
CH2CH3



2-117
Q2b
(CH2)2CH3






2-118
Q2b


embedded image








2-119
Q2b


embedded image








2-120
Q2b


embedded image























TABLE 30










physical






property



compound


(melting



number
Q
R1
point-ND)









2-121
Q2b


embedded image










2-122
Q2b


embedded image










2-123
Q2b


embedded image










2-124
Q2b


embedded image










2-125
Q2b


embedded image










2-126
Q2b
CF3




2-127
Q2b
CH2CF3




2-128
Q2b
CF2CF3




2-129
Q2b
CH2CH═CH2




2-130
Q2b
CH2C≡CH




2-131
Q2b
C6H5




2-132
Q2b
CH2C6H5




2-133
Q2b
CH2OCH3




2-134
Q2b
CH2OCH2CH3




2-135
Q2b
CH2O(CH2)2CH3




2-136
Q2b
(CH2)2OCH3




2-137
Q2b
(CH2)3OCH3








2-138
Q2b


embedded image










2-139
Q2b


embedded image










2-140
Q2b


embedded image










2-141
Q2b


embedded image










2-142
Q2b
CH2OCH2CF3




2-143
Q2b
CH2OCF2CHF2




2-144
Q2b
CH2OCH2CF2CF3




2-145
Q2b
CH2OCH2CH═CH2




2-146
Q2b
CH2OCH2CH═CCl2




2-147
Q2b
CH2OCH2CF═CF2




2-148
Q2b
CH2OC2C≡CH




2-149
Q2b
CH2OCH2C≡CCH3




2-150
Q2b
CH2SCH3




2-151
Q2b
CH2SCH2CH3




2-152
Q2b
CH2S(CH2)2CH3








2-153
Q2b


embedded image










2-154
Q2b


embedded image










2-155
Q2b


embedded image










2-156
Q2b


embedded image










2-157
Q2b
CH2SCH2CF3




2-158
Q2b
CH2SCH2CH═CH2




2-159
Q2b
CH2SCH2C≡CH




2-160
Q2b
CH2SOCH3




















TABLE 31








physical





property


compound


(melting


number
Q
R1
point-ND)







2-161
Q2b
CH2SOCH2CH3



2-162
Q2b
CH2SO(CH2)2CH3






2-163
Q2b


embedded image








2-164
Q2b


embedded image








2-165
Q2b


embedded image








2-166
Q2b


embedded image








2-167
Q2b
CH2SOCH2CF3



2-168
Q2b
CH2SOCH2CH═CH2



2-169
Q2b
CH2SOCH2C≡CH



2-170
Q2b
CH2SO2CH3



2-171
Q2b
CH2SO2CH2CH3



2-172
Q2b
CH2SO2(CH2)2CH3






2-173
Q2b


embedded image








2-174
Q2b


embedded image








2-175
Q2b


embedded image








2-176
Q2b


embedded image








2-177
Q2b
CH2SO2CH2CF3



2-178
Q2b
CH2SO2CH2CH═CH2



2-179
Q2b
CH2SO2CH2C≡CH



2-180
Q2b
CH2O(CH2)2OCH3



2-181
Q2b
CH2O(CH2)2OCH2CH3






2-182
Q2b


embedded image








2-183
Q2b
CH2O(CH2)2OCH2CF3



2-184
Q2b
CH2O(CH2)2OCH2CH═CH2



2-185
Q2b
CH2O(CH2)2OCH2C≡CH



2-186
Q2b
CH2O(CH2)2SCH3






2-187
Q2b


embedded image








2-188
Q2b
CH2O(CH2)2SCH2CF3



2-189
Q2b
CH2O(CH2)2SCH2CH═CH2



2-190
Q2b
CH2O(CH2)2SCH2C≡CH



2-191
Q2b
CH2O(CH2)2SOCH3






2-192
Q2b


embedded image








2-193
Q2b
CH2O(CH2)2SOCH2CF3



2-194
Q2b
CH2O(CH2)2SOCH2CH═CH2



2-195
Q2b
CH2O(CH2)2SOCH2C≡CH



2-196
Q2b
CH2O(CH2)2SO2CH3






2-197
Q2b


embedded image








2-198
Q2b
CH2O(CH2)2SO2CH2CF3



2-199
Q2b
CH2O(CH2)2SO2CH2CH═CH2



2-200
Q2b
CH2O(CH2)2SO2CH2C≡CH



















TABLE 32








physical





property


compound


(melting


number
Q
R1
point-ND)







2-201
Q2b


embedded image








2-202
Q2b


embedded image








2-203
Q2b


embedded image








2-204
Q2b


embedded image








2-205
Q2b


embedded image








2-206
Q2b


embedded image








2-207
Q2b


embedded image








2-208
Q2b


embedded image








2-209
Q2b
CH2O(CH2)2NHSO2CH3



2-210
Q2b
CH2O(CH2)2N(CH3)(SO2CH3)






2-211
Q2b


embedded image








2-212
Q2b
CH2O(CH2)2NHSO2CF3



2-213
Q2b
CH2O(CH2)2NHSO2CHF2



2-214
Q2b
CH2O(CH2)2NHSO2CH2CF3



2-215
Q2b
SCH3



2-216
Q2b
SOCH3



2-217
Q2b
SO2CH3



2-218
Q2b
OCH3



2-219
Q2b
OCH2CH3



2-220
Q2b
O(CH2)2CH3



2-221
Q2b
OCH2CF3



2-222
Q2b
OCF2CF3



2-223
Q2b
O(CH2)2OCH3



2-224
Q2b
NHCH3



2-225
Q2b
NHCH2CH3



2-226
Q2b
N(CH3)2



2-227
Q2b
N(CH2CH3)2



2-228
Q2b
N(CH3)(CH2CH3)



2-229
Q2c
CH3
NMR


2-230
Q2c
CH2CH3



2-231
Q2c
(CH2)2CH3






2-232
Q2c


embedded image








2-233
Q2c


embedded image








2-234
Q2c


embedded image








2-235
Q2c


embedded image








2-236
Q2c


embedded image








2-237
Q2c


embedded image








2-238
Q2c


embedded image








2-239
Q2c


embedded image








2-240
Q2c
CF3





















TABLE 33










physical






property



compound


(melting



number
Q
R1

text missing or illegible when filed










2-241
Q2c
CH2CF3




2-242
Q2c
CF2CF3




2-243
Q2c
CH2CH═CH2




2-244
Q2c
CH2C≡CH




2-245
Q2c
C6C5




2-246
Q2c
CH2C6C5




2-247
Q2c
CH2OCH3




2-248
Q2c
CH2OCH2CH3




2-249
Q2c
CH2O(CH2)2CH3




2-250
Q2c
(CH2)2OCH3




2-251
Q2c
(CH2)3OCH3








2-252
Q2c


embedded image










2-253
Q2c


embedded image










2-254
Q2c


embedded image










2-255
Q2c


embedded image










2-256
Q2c
CH2OCH2CF3




2-257
Q2c
CH2OCF2CHF2




2-258
Q2c
CH2OCH2CF2CF3




2-259
Q2c
CH2OCH2CH═CH2




2-260
Q2c
CH2OCH2CH═CCl2




2-261
Q2c
CH2OCH2CF═CF2




2-262
Q2c
CH2OC2C≡CH




2-263
Q2c
CH2OCH2C≡CCH3




2-264
Q2c
CH2SCH3




2-265
Q2c
CH2SCH2CH3




2-266
Q2c
CH2S(CH2)2CH3








2-267
Q2c


embedded image










2-268
Q2c


embedded image










2-269
Q2c


embedded image










2-270
Q2c


embedded image










2-271
Q2c
CH2SCH2CF3




2-272
Q2c
CH2SCH2CH═CH2




2-273
Q2c
CH2SCH2C≡CH




2-274
Q2c
CH2SOCH3




2-275
Q2c
CH2SOCH2CH3




2-276
Q2c
CH2SO(CH2)2CH3








2-277
Q2c


embedded image










2-278
Q2c


embedded image










2-279
Q2c


embedded image










2-280
Q2c


embedded image










text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 34








physical





property


compound


(melting


number
Q
R1
point-ND)







2-281
Q2c
CH2SOCH2CF3



2-282
Q2c
CH2SOCH2CH═CH2



2-283
Q2c
CH2SOCH2C≡CH



2-284
Q2c
CH2SO2CH3



2-285
Q2c
CH2SO2CH2CH3



2-286
Q2c
CH2SO2(CH2)2CH3






2-287
Q2c


embedded image








2-288
Q2c


embedded image








2-289
Q2c


embedded image








2-290
Q2c


embedded image








2-291
Q2c
CH2SO2CH2CF3



2-292
Q2c
CH2SO2CH2CH═CH2



2-293
Q2c
CH2SO2CH2C≡CH



2-294
Q2c
CH2O(CH2)2OCH3



2-295
Q2c
CH2O(CH2)2OCH2CH3






2-296
Q2c


embedded image








2-297
Q2c
CH2O(CH2)2OCH2CF3



2-298
Q2c
CH2O(CH2)2OCH2CH═CH2



2-299
Q2c
CH2O(CH2)2OCH2C≡CH



2-300
Q2c
CH2O(CH2)2SCH3






2-301
Q2c


embedded image








2-302
Q2c
CH2O(CH2)2SCH2CF3



2-303
Q2c
CH2O(CH2)2SCH2CH═CH2



2-304
Q2c
CH2O(CH2)2SCH2C≡CH



2-305
Q2c
CH2O(CH2)2SOCH3






2-306
Q2c


embedded image








2-307
Q2c
CH2O(CH2)2SOCH2CF3



2-308
Q2c
CH2O(CH2)2SOCH2CH═CH2



2-309
Q2c
CH2O(CH2)2SOCH2C≡CH



2-310
Q2c
CH2O(CH2)2SO2CH3






2-311
Q2c


embedded image








2-312
Q2c
CH2O(CH2)2SO2CH2CF3



2-313
Q2c
CH2O(CH2)2SO2CH2CH═CH2



2-314
Q2c
CH2O(CH2)2SO2CH2C≡CH






2-315
Q2c


embedded image








2-316
Q2c


embedded image








2-317
Q2c


embedded image








2-318
Q2c


embedded image








2-319
Q2c


embedded image








2-320
Q2c


embedded image





















TABLE 35








physical





property


com-


(melting


pound


point-


number

text missing or illegible when filed

Rtext missing or illegible when filed
ND)







2-321

text missing or illegible when filed 2c


embedded image








2-322

text missing or illegible when filed 2c


embedded image








2-323

text missing or illegible when filed 2c
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



2-324

text missing or illegible when filed 2c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SO2CH3)






2-325

text missing or illegible when filed 2c


embedded image








2-326

text missing or illegible when filed 2c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CF3



2-327

text missing or illegible when filed 2c
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CHF3



2-328

text missing or illegible when filed 2c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CH2CF3



2-329

text missing or illegible when filed 2c
SCH3



2-330

text missing or illegible when filed 2c
SOCH3



2-331

text missing or illegible when filed 2c
SO2CH3



2-332

text missing or illegible when filed 2c
OCH3



2-333

text missing or illegible when filed 2c
OCH2CH3



2-334

text missing or illegible when filed 2c
O(CHtext missing or illegible when filed )text missing or illegible when filed CH3



2-335

text missing or illegible when filed 2c
OCH2CF3



2-336

text missing or illegible when filed 2c
OCFtext missing or illegible when filed CFtext missing or illegible when filed



2-337

text missing or illegible when filed 2c

text missing or illegible when filed (CHtext missing or illegible when filed )text missing or illegible when filed OCH3



2-338

text missing or illegible when filed 2c
NHCH3



2-339

text missing or illegible when filed 2c
NHCH2CH3



2-340

text missing or illegible when filed 2c
N(CHtext missing or illegible when filed )text missing or illegible when filed



2-341

text missing or illegible when filed 2c
N(CH2CHtext missing or illegible when filed )text missing or illegible when filed



2-342

text missing or illegible when filed 2c
N(CHtext missing or illegible when filed )(CHtext missing or illegible when filed CHtext missing or illegible when filed )



2-343

text missing or illegible when filed 2d
CH3



2-344

text missing or illegible when filed 2d
CH2CH3



2-345

text missing or illegible when filed 2d
(CHtext missing or illegible when filed )text missing or illegible when filed CH3






2-346

text missing or illegible when filed 2d


embedded image








2-347

text missing or illegible when filed 2d


embedded image








2-348

text missing or illegible when filed 2d


embedded image








2-349

text missing or illegible when filed 2d


embedded image








2-350

text missing or illegible when filed 2d


embedded image








2-351

text missing or illegible when filed 2d


embedded image








2-352

text missing or illegible when filed 2d


embedded image








2-353

text missing or illegible when filed 2d


embedded image








2-354

text missing or illegible when filed 2d
CF3



2-355

text missing or illegible when filed 2d
CH2CF3



2-356

text missing or illegible when filed 2d
CF2CF3



2-357

text missing or illegible when filed 2d
CH2CH═CH2



2-358

text missing or illegible when filed 2d
CH2C≡CH



2-359

text missing or illegible when filed 2d
Ctext missing or illegible when filed Htext missing or illegible when filed



2-360

text missing or illegible when filed 2d
CH2Ctext missing or illegible when filed Htext missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed

















TABLE 36









physical






property






(melting



compound


point-



number
Q
R1
ND)







 
2-361
Q2d
CH2OCH3




2-362
Q2d
CH2OCH2CH3




2-363
Q2d
CH2O(CH2)2CH3




2-364
Q2d
(CH2)2OCH3




2-365
Q2d
(CH2)3OCH3







2-366
Q2d


embedded image









2-367
Q2d


embedded image









2-368
Q2d


embedded image









2-369
Q2d


embedded image









2-370
Q2d
CH2OCH2CF3




2-371
Q2d
CH2OCF2CHF2




2-372
Q2d
CH2OCH2CF2CF3




2-373
Q2d
CH2OCH2CH═CH2




2-374
Q2d
CH2OCH2CH═CCl2




2-375
Q2d
CH2OCH2CF═CF2




2-376
Q2d
CH2OC2C≡CH




2-377
Q2d
CH2OCH2C≡CCH3




2-378
Q2d
CH2SCH3




2-379
Q2d
CH2SCH2CH3




2-380
Q2d
CH2S(CH2)2CH3







2-381
Q2d


embedded image









2-382
Q2d


embedded image









2-383
Q2d


embedded image









2-384
Q2d


embedded image









2-385
Q2d
CH2SCH2CF3




2-386
Q2d
CH2SCH2CH═CH2




2-387
Q2d
CH2SCH2C≡CH




2-388
Q2d
CH2SOCH3




2-389
Q2d
CH2SOCH2CH3




2-390
Q2d
CH2SO(CH2)2CH3







2-391
Q2d


embedded image









2-392
Q2d


embedded image









2-393
Q2d


embedded image









2-394
Q2d


embedded image









2-395
Q2d
CH2SOCH2CF3




2-396
Q2d
CH2SOCH2CH═CH2




2-397
Q2d
CH2SOCH2C≡CH




2-398
Q2d
CH2SO2CH3




2-399
Q2d
CH2SO2CH2CH3




2-400
Q2d
CH2SO2(CH2)2CH3



















TABLE 37








physical





property


compound


(melting


number
Q
R1
point-ND)







2-401
Q2d


embedded image








2-402
Q2d


embedded image








2-403
Q2d


embedded image








2-404
Q2d


embedded image








2-405
Q2d
CH2SO2CH2CF3



2-406
Q2d
CH2SO2CH2CH═CH2



2-407
Q2d
CH2SO2CH2C≡CH



2-408
Q2d
CH2O(CH2)2OCH3



2-409
Q2d
CH2O(CH2)2OCH2CH3






2-410
Q2d


embedded image








2-411
Q2d
CH2O(CH2)2OCH2CF3



2-412
Q2d
CH2O(CH2)2OCH2CH═CH2



2-413
Q2d
CH2O(CH2)2OCH2C≡CH



2-414
Q2d
CH2O(CH2)2SCH3






2-415
Q2d


embedded image








2-416
Q2d
CH2O(CH2)2SCH2CF3



2-417
Q2d
CH2O(CH2)2SCH2CH═CH2



2-418
Q2d
CH2O(CH2)2SCH2C≡CH



2-419
Q2d
CH2O(CH2)2SOCH3






2-420
Q2d


embedded image








2-421
Q2d
CH2O(CH2)2SOCH2CF3



2-422
Q2d
CH2O(CH2)2SOCH2CH═CH2



2-423
Q2d
CH2O(CH2)2SOCH2C≡CH



2-424
Q2d
CH2O(CH2)2SO2CH3






2-425
Q2d


embedded image








2-426
Q2d
CH2O(CH2)2SO2CH2CF3



2-427
Q2d
CH2O(CH2)2SO2CH2CH═CH2



2-428
Q2d
CH2O(CH2)2SO2CH2C≡CH






2-429
Q2d


embedded image








2-430
Q2d


embedded image








2-431
Q2d


embedded image








2-432
Q2d


embedded image








2-433
Q2d


embedded image








2-434
Q2d


embedded image








2-435
Q2d


embedded image








2-436
Q2d


embedded image








2-437
Q2d
CH2O(CH2)2NHSO2CH3



2-438
Q2d
CH2O(CH2)2N(CH3)(SO2CH3)






2-439
Q2d


embedded image








2-440
Q2d
CH2O(CH2)2NHSO2CF3




















TABLE 38









physical






property



compound


(melting



number
Q
R1
point-ND)








2-441
Q2d
CH2O(CH2)2NHSO2CHF3




2-442
Q2d
CH2O(CH2)2NHSO2CH2CF3




2-443
Q2d
SCH3




2-444
Q2d
SOCH3




2-445
Q2d
SO2CH3




2-446
Q2d
OCH3




2-447
Q2d
OCH2CH3




2-448
Q2d
O(CH2)2CH3




2-449
Q2d
OCH2CF3




2-450
Q2d
OCF2CF3




2-451
Q2d
O(CH2)2OCH3




2-452
Q2d
NHCH3




2-453
Q2d
NHCH2CH3




2-454
Q2d
N(CH3)2




2-455
Q2d
N(CH2CH3)2




2-456
Q2d
N(CH3)(CH2CH3)




2-457
Q2e
CH3




2-458
Q2e
CH2CH3




2-459
Q2e
(CH2)2CH3







2-460
Q2e


embedded image









2-461
Q2e


embedded image









2-462
Q2e


embedded image









2-463
Q2e


embedded image









2-464
Q2e


embedded image









2-465
Q2e


embedded image









2-466
Q2e


embedded image









2-467
Q2e


embedded image









2-468
Q2e
CF3




2-469
Q2e
CH2CF3




2-470
Q2e
CF2CF3




2-471
Q2e
CH2CH═CH2




2-472
Q2e
CH2C═CH




2-473
Q2e
C6H5




2-474
Q2e
CH2C6H5




2-475
Q2e
CH2OCH3




2-476
Q2e
CH2OCH2CH3




2-477
Q2e
CH2O(CH2)2CH3




2-478
Q2e
(CH2)2OCH3




2-479
Q2e
(CH2)3OCH3







2-480
Q2e


embedded image





















TABLE 39








physical





property


compound


(melting


number
Q
R1
point-ND)







2-481
Q2e


embedded image








2-482
Q2e


embedded image








2-483
Q2e


embedded image








2-484
Q2e
CH2OCH2CF3



2-485
Q2e




2-486
Q2e
CH2OCH2CF2CF3



2-487
Q2e
CH2OCH2CH═CH2



2-488
Q2e
CH2OCH2CH═CCl2



2-489
Q2e
CH2OCH2CF═CF2



2-490
Q2e
CH2OC2C═CH



2-491
Q2e
CH2OCH2C═CCH3



2-492
Q2e
CH3SCH3



2-493
Q2e
CH2SCH2CH3



2-494
Q2e
CH2S(CH2)2CH3






2-495
Q2e


embedded image








2-496
Q2e


embedded image








2-497
Q2e


embedded image








2-498
Q2e


embedded image








2-499
Q2e
CH2SCH2CF3



2-500
Q2e
CH2SCH2CH═CH2



2-501
Q2e
CH2SCH2C≡CH



2-502
Q2e
CH3SOCH3



2-503
Q2e
CH2SOCH2CH3



2-504
Q2e
CH2SO(CH2)2CH3






2-505
Q2e


embedded image








2-506
Q2e


embedded image








2-507
Q2e


embedded image








2-508
Q2e


embedded image








2-509
Q2e
CH2SOCH2CF3



2-510
Q2e
CH2SOCH2CH═CH2



2-511
Q2e
CH2SOCH2C≡CH



2-512
Q2e
CH2SO2CH3



2-513
Q2e
CH2SO2CH2CH3



2-514
Q2e
CH2SO2(CH2)2CH3






2-515
Q2e


embedded image








2-516
Q2e


embedded image








2-517
Q2e


embedded image








2-518
Q2e


embedded image








2-519
Q2e
CH2SO2CH2CF3



2-520
Q2e
CH3SO2CH2CH═CH2





















TABLE 40










physical






property



compound


(melting



number
Q
R1
point-ND)









2-521
Q2e
CH2SO2CH2C≡CH




2-522
Q2e
CH2O(CH2)2OCH3




2-523
Q2e
CH2O(CH2)2OCH2CH3








2-524
Q2e


embedded image










2-525
Q2e
CH2O(CH2)2OCH2CF3




2-526
Q2e
CH2O(CH2)2OCH2CH═CH2




2-527
Q2e
CH2O(CH2)2OCH2C≡CH




2-528
Q2e
CH2O(CH2)2SCH3








2-529
Q2e


embedded image










2-530
Q2e
CH2O(CH2)2SCH2CF3




2-531
Q2e
CH2O(CH2)2SCH2CH═CH2




2-532
Q2e
CH2O(CH2)2SCH2C≡CH




2-533
Q2e
CH2O(CH2)2SOCH3








2-534
Q2e


embedded image










2-535
Q2e
CH2O(CH2)2SOCH2CF3




2-536
Q2e
CH2O(CH2)2SOCH2CH═CH2




2-537
Q2e
CH2O(CH2)2SOCH2C≡CH




2-538
Q2e
CH2O(CH2)2SO2CH3








2-539
Q2e


embedded image










2-540
Q2e
CH2O(CH2)2SO2CH2CF3




2-541
Q2e
CH2O(CH2)2SO2CH2CH═CH2




2-542
Q2e
CH2O(CH2)2SO2CH2C≡CH








2-543
Q2e


embedded image










2-544
Q2e


embedded image










2-545
Q2e


embedded image










2-546
Q2e


embedded image










2-547
Q2e


embedded image










2-548
Q2e


embedded image










2-549
Q2e


embedded image










2-550
Q2e


embedded image










2-551
Q2e
CH2O(CH2)2NHSO2CH3




2-552
Q2e
CH2O(CH2)2N(CH3)(SO2CH3)








2-553
Q2e


embedded image










2-554
Q2e
CH2O(CH2)2NHSO2CF3




2-555
Q2e
CH2O(CH2)2NHSO2CHF2




2-556
Q2e
CH2O(CH2)2NHSO2CH2CF3




2-557
Q2e
SCH3




2-558
Q2e
SOCH3




2-559
Q2e
SO2CH3




2-560
Q2e
OCH3




















TABLE 41








physical





property


compound


(melting


number
Q
R1
point-ND)







2-561
Q2e
OCH2CH3



2-562
Q2e
O(CH2)2CH3



2-563
Q2e
OCH2CF3



2-564
Q2e
OCF2CF3



2-565
Q2e
O(CH2)2OCH3



2-566
Q2e
NHCH3



2-567
Q2e
NHCH2CH3



2-568
Q2e
N(CH3)2



2-569
Q2e
N(CH2CH3)2



2-570
Q2e
N(CH3)(CH2CH3)



2-571
Q2f
CH3



2-572
Q2f
CH2CH3



2-573
Q2f
(CH2)2CH3






2-574
Q2f


embedded image








2-575
Q2f


embedded image








2-576
Q2f


embedded image








2-577
Q2f


embedded image








2-578
Q2f


embedded image








2-579
Q2f


embedded image








2-580
Q2f


embedded image








2-581
Q2f


embedded image








2-582
Q2f
CF3



2-583
Q2f
CH2CF3



2-584
Q2f
CF2CF3



2-585
Q2f
CH2CH═CH2



2-586
Q2f
CH2C≡CH



2-587
Q2f
C6H5



2-588
Q2f
CH2C6H5



2-589
Q2f
CH2OCH3



2-590
Q2f
CH2OCH2CH3



2-591
Q2f
CH2O(CH2)2CH3



2-592
Q2f
(CH2)2OCH3



2-593
Q2f
(CH2)3OCH3






2-594
Q2f


embedded image








2-595
Q2f


embedded image








2-596
Q2f


embedded image








2-597
Q2f


embedded image








2-598
Q2f
CH2OCH2CF3



2-599
Q2f
CH2OCF2CHF2



2-600
Q2f
CH2OCH2CF2CF3



















TABLE 42








physical





property


compound


(melting


number
D
R1
point-ND)







2-601
Q2f
CH2OCH2CH═CH2



2-602
Q2f
CH2OCH2CH═CCl2



2-603
Q2f
CH2OCH2CF═CF3



2-604
Q2f
CH2OC2C≡CH



2-605
Q2f
CH2OCH2C≡CCH3



2-606
Q2f
CH2SCH3



2-607
Q2f
CH2SCH2CH3



2-608
Q2f
CH2S(CH2)2CH3






2-609
Q2f


embedded image








2-610
Q2f


embedded image








2-611
Q2f


embedded image








2-612
Q2f


embedded image








2-613
Q2f
CH2SCH2CF3



2-614
Q2f
CH2SCH2CH═CH3



2-615
Q2f
CH2SCH2C≡CH



2-616
Q2f
CH2SOCH3



2-617
Q2f
CH2SOCH2CH3



2-618
Q2f
CH2SO(CH2)2CH3






2-619
Q2f


embedded image








2-620
Q2f


embedded image








2-621
Q2f


embedded image








2-622
Q2f


embedded image








2-623
Q2f
CH2SOCH2CF3



2-624
Q2f
CH2SOCH2CH═CH2



2-625
Q2f
CH2SOCH2C≡CH



2-626
Q2f
CH2SO2CH3



2-627
Q2f
CH2SO2CH2CH3



2-628
Q2f
CH2SO2(CH3)2CH3






2-629
Q2f


embedded image








2-630
Q2f


embedded image








2-631
Q2f


embedded image








2-632
Q2f


embedded image








2-633
Q2f
CH2SO2CH2CF3



2-634
Q2f
CH2SO2CH2CH═CH2



2-635
Q2f
CH2SO2CH2C≡CH



2-636
Q2f
CH2O(CH2)2OCH3



2-637
Q2f
CH2O(CH2)2OCH2CH3






2-638
Q2f


embedded image








2-639
Q2f
CH2O(CH2)2OCH2CF3



2-640
Q2f
CH2O(CH2)2OCH2CH═CH2



















TABLE 43








physical





property


compound


(melting


number
Q
R1
point-ND)







2-641
Q2f
CH2O(CH2)2OCH2C≡CH



2-642
Q2f
CH2O(CH2)2SCH3






2-643
Q2f


embedded image








2-644
Q2f
CH2O(CH2)2SCH2CF3



2-645
Q2f
CH2O(CH2)2SCH2CH═CH2



2-646
Q2f
CH2O(CH2)2SCH2C≡CH



2-647
Q2f
CH2O(CH2)2SOCH3






2-648
Q2f


embedded image








2-649
Q2f
CH2O(CH2)2SOCH2CF3



2-650
Q2f
CH2O(CH2)2SOCH2CH═CH2



2-651
Q2f
CH2O(CH2)2SOCH2C≡CH



2-652
Q2f
CH2O(CH2)2SO2CH3






2-653
Q2f


embedded image








2-654
Q2f
CH2O(CH2)2SO2CH2CF3



2-655
Q2f
CH2O(CH2)2SO2CH2CH═CH2



2-656
Q2f
CH2O(CH2)2SO2CH2C≡CH






2-657
Q2f


embedded image








2-658
Q2f


embedded image








2-659
Q2f


embedded image








2-660
Q2f


embedded image








2-661
Q2f


embedded image








2-662
Q2f


embedded image








2-663
Q2f


embedded image








2-664
Q2f


embedded image








2-665
Q2f
CH2O(CH2)2NHSO2CH3



2-666
Q2f
CH2O(CH2)2N(CH3)(SO2CH3)






2-667
Q2f


embedded image








2-668
Q2f
CH2O(CH2)2NHSO2CF3



2-669
Q2f
CH2O(CH2)2NHSO2CHF2



2-670
Q2f
CH2O(CH2)2NHSO2CH2CF3



2-671
Q2f
SCH3



2-672
Q2f
SOCH3



2-673
Q2f
SO2CH3



2-674
Q2f
OCH3



2-675
Q2f
OCH2CH3



2-676
Q2f
O(CH2)2CH3



2-677
Q2f
OCH2CF3



2-678
Q2f
OCF2CF3



2-679
Q2f
O(CH2)2OCH3



2-680
Q2f
NHCH3



















TABLE 44





compound


physical property


number
Q
R1
(melting point-ND)

















2-681
Q2f
NHCH2CH3


2-682
Q2f
N(CH3)2


2-683
Q2f
N(CH2CH3)


2-684
Q2f
N(CH3)(CH2CH3)
















TABLE 45









embedded image









embedded image

 embedded image







embedded image

 embedded image







embedded image

 embedded image
















physical





property


compound


(melting


number
Q
R1
point-ND)





3-1
Q3a
CH3



3-2
Q3a
CH2CH3



3-3
Q3a
(CH2)2CH3






3-4
Q3a


embedded image








3-5
Q3a


embedded image








3-6
Q3a


embedded image








3-7
Q3a


embedded image








3-8
Q3a


embedded image








3-9
Q3a


embedded image








3-10
Q3a


embedded image








3-11
Q3a


embedded image








3-12
Q3a
CF3



3-13
Q3a
CH2CF2



3-14
Q3a
CF2CF3



3-15
Q3a
CH2CH═CH2



3-16
Q3a
CH2C≡CH



3-17
Q3a
C6H6



3-18
Q3a
CH2C6H6



3-19
Q3a
CH2OCH3



3-20
Q3a
CH2OCH2CH3



3-21
Q3a
CH2O(CH2)2CH3



3-22
Q3a
(CH2)2OCH3



3-23
Q3a
(CH2)3OCH3






3-24
Q3a


embedded image








3-25
Q3a


embedded image








3-26
Q3a


embedded image








3-27
Q3a


embedded image








3-28
Q3a
CH2OCH2CF3



3-29
Q3a
CH2OCF2CHF2



3-30
Q3a
CH2OCH2CF2CF3



3-31
Q3a
CH2OCH2CH═CH2



3-32
Q3a
CH2OCH2CH═CCl2



3-33
Q3a
CH2OCH2CF═CF2



3-34
Q3a
CH2OC2C≡CH



3-35
Q3a
CH2OCH2C≡CCH3



3-36
Q3a
CH2SCH3



3-37
Q3a
CH2SCH2CH3



3-38
Q3a
CH2S(CH2)2CH3






3-39
Q3a


embedded image








3-40
Q3a


embedded image























TABLE 46










physical






property



compound


(melting



number
Q
R1
point-ND)









3-41
Q3a


embedded image










3-42
Q3a


embedded image










3-43
Q3a
CH2SCH2CF3




3-44
Q3a
CH2SCH2CH═CH2




3-45
Q3a
CH2SCH2C═CH




3-46
Q3a
CH2SOCH3




3-47
Q3a
CH2SOCH2CH3




3-48
Q3a
CH2SO(CH2)2CH3








3-49
Q3a


embedded image










3-50
Q3a


embedded image










3-51
Q3a


embedded image










3-52
Q3a


embedded image










3-53
Q3a
CH2SOCH2CF3




3-54
Q3a
CH2SOCH2CH═CH2




3-55
Q3a
CH2SOCH2C≡CH




3-56
Q3a
CH2SO2CH3




3-57
Q3a
CH2SO2CH2CH3




3-58
Q3a
CH2SO2(CH2)2CH3








3-59
Q3a


embedded image










3-60
Q3a


embedded image










3-61
Q3a


embedded image










3-62
Q3a


embedded image










3-63
Q3a
CH2SO2CH2CF3




3-64
Q3a
CH2SO2CH2CF3




3-65
Q3a
CH2SO2CH2C≡CH




3-66
Q3a
CH2O(CH2)2OCH3




3-67
Q3a
CH2O(CH2)2OCH2CH3








3-68
Q3a


embedded image










3-69
Q3a
CH2O(CH2)2OCH2CF3




3-70
Q3a
CH2O(CH2)2OCH2CH═CH2




3-71
Q3a
CH2O(CH2)2OCH2C≡CH




3-72
Q3a
CH2O(CH2)2SCH3








3-73
Q3a


embedded image










3-74
Q3a
CH2O(CH2)2SCH2CF3




3-75
Q3a
CH2O(CH2)2SCH2CH═CH2




3-76
Q3a
CH2O(CH2)2SCH2C≡CH




3-77
Q3a
CH2O(CH2)2SOCH3








3-78
Q3a


embedded image










3-79
Q3a
CH2O(CH2)2SOCH2CF3




3-80
Q3a
CH2O(CH2)2SOCH2CH═CH2


























physical





property


compound


(melting


number
Q
R1

text missing or illegible when filed








3-81
Q3a
CH2O(CH2)2SOCH2Ctext missing or illegible when filed CH



3-82
Q3a
CH2O(CH2)2SO2CH3






3-83
Q3a


embedded image








3-84
Q3a
CH2O(CH2)2SO2CH2CF3



3-85
Q3a
CH2O(CH2)2SO2CH2CH═CH2



3-86
Q3a
CH2O(CH2)2SO2CH2Ctext missing or illegible when filed CH






3-87
Q3a


embedded image








3-88
Q3a


embedded image








3-89
Q3a


embedded image








3-90
Q3a


embedded image








3-91
Q3a


embedded image








3-92
Q3a


embedded image








3-93
Q3a


embedded image








3-94
Q3a


embedded image








3-95
Q3a
CH2O(CH2)2NHSO2CH3



3-96
Q3a
CH2O(CH2)2N(CH3)(SO2CH3)






3-97
Q3a


embedded image








3-98
Q3a
CH2O(CH2)2NHSO2CF3



3-99
Q3a
CH2O(CH2)2NHSO2CHF2



3-100
Q3a
CH2O(CH2)2NHSO2CH2CF3



3-101
Q3a
SCH3



3-102
Q3a
SOCH3



3-103
Q3a
SO2CH3



3-104
Q3a
OCH3



3-105
Q3a
OCH2CH3



3-106
Q3a
O(CH2)2CH3



3-107
Q3a
OCH2CF3



3-108
Q3a
OCF2CF3



3-109
Q3a
O(CH2)2OCH3



3-110
Q3a
NHCH3



3-111
Q3a
NHCH2CH3



3-112
Q3a
N(CH3)2



3-113
Q3a
N(CH2CH3)2



3-114
Q3a
N(CH3)(CH2CH3)



3-115
Q3b
CH3
NMR


3-116
Q3b
CH2CH3



3-117
Q3b
(CH2)2CH3






3-118
Q3b


embedded image








3-119
Q3b


embedded image








3-120
Q3b


embedded image








text missing or illegible when filed indicates data missing or illegible when filed

















TABLE 48









physical






property






(melting



compound


point-



number
Q
R1
ND)







 
3-121
Q3b


embedded image









3-122
Q3b


embedded image









3-123
Q3b


embedded image









3-124
Q3b


embedded image









3-125
Q3b


embedded image









3-126
Q3b
CF3




3-127
Q3b
CH2CF3




3-128
Q3b
CF2CF3




3-129
Q3b
CH2CH═CH2




3-130
Q3b
CH2C≡CH




3-131
Q3b
C6H5




3-132
Q3b
CH2C6H5




3-133
Q3b
CH2OCH3




3-134
Q3b
CH2OCH2CH3




3-135
Q3b
CH2O(CH2)2CH3




3-136
Q3b
(CH2)2OCH3




3-137
Q3b
(CH2)3OCH3







3-138
Q3b


embedded image









3-139
Q3b


embedded image









3-140
Q3b


embedded image









3-141
Q3b


embedded image









3-142
Q3b
CH2OCH2CF3




3-143
Q3b
CH2OCF2CHF2




3-144
Q3b
CH2OCH2CF2CF3




3-145
Q3b
CH2OCH2CH═CH2




3-146
Q3b
CH2OCH2CH═CCl2




3-147
Q3b
CH2OCH2CF═CF2




3-148
Q3b
CH2OC2C≡CH




3-149
Q3b
CH2OCH2C≡CCH3




3-150
Q3b
CH2SCH3




3-151
Q3b
CH2SCH2CH3




3-152
Q3b
CH2S(CH2)2CH3







3-153
Q3b


embedded image









3-154
Q3b


embedded image









3-155
Q3b


embedded image









3-156
Q3b


embedded image









3-157
Q3b
CH2SCH2CF3




3-158
Q3b
CH2SCH2CH═CH2




3-159
Q3b
CH2SCH2C≡CH




3-160
Q3b
CH2SOCH3



















TABLE 49








physical





property


compound


(melting


number
Q
R1
point-ND)







3-161
Q3b
CH2SOCH2CH3



3-162
Q3b
CH2SO(CH2)2CH3






3-163
Q3b


embedded image








3-164
Q3b


embedded image








3-165
Q3b


embedded image








3-166
Q3b


embedded image








3-167
Q3b
CH2SOCH2CF3



3-168
Q3b
CH2SOCH2CH═CH2



3-169
Q3b
CH2SOCH2C≡CH



3-170
Q3b
CH2SO2CH3



3-171
Q3b
CH2SO2CH2CH3



3-172
Q3b
CH2SO2(CH2)2CH3






3-173
Q3b


embedded image








3-174
Q3b


embedded image








3-175
Q3b


embedded image








3-176
Q3b


embedded image








3-177
Q3b
CH2SO2CH2CF3



3-178
Q3b
CH2SO2CH2CH═CH2



3-179
Q3b
CH2SO2CH2C≡CH



3-180
Q3b
CH2O(CH2)2OCH3



3-181
Q3b
CH2O(CH2)2OCH2CH3






3-182
Q3b


embedded image








3-183
Q3b
CH2O(CH2)2OCH2CF3



3-184
Q3b
CH2O(CH2)2OCH2CH═CH2



3-185
Q3b
CH2O(CH2)2OCH2C≡CH



3-186
Q3b
CH2O(CH2)2SCH3






3-187
Q3b


embedded image








3-188
Q3b
CH2O(CH2)2SCH2CF3



3-189
Q3b
CH2O(CH2)2SCH2CH═CH2



3-190
Q3b
CH2O(CH2)2SCH2C≡CH



3-191
Q3b
CH2O(CH2)2SOCH3






3-192
Q3b


embedded image








3-193
Q3b
CH2O(CH2)2SOCH2CF3



3-194
Q3b
CH2O(CH2)2SOCH2CH═CH2



3-195
Q3b
CH2O(CH2)2SOCH2C≡CH



3-196
Q3b
CH2O(CH2)2SO2CH3






3-197
Q3b


embedded image








3-198
Q3b
CH2O(CH2)2SO2CH2CF3



3-199
Q3b
CH2O(CH2)2SO2CH═CH2



3-200
Q3b
CH2O(CH2)2SO2CH2C≡CH



















TABLE 50








physical





property


compound


(melting


number
Q
R1
point-ND)







3-201
Q3b


embedded image








3-202
Q3b


embedded image








3-203
Q3b


embedded image








3-204
Q3b


embedded image








3-205
Q3b


embedded image








3-206
Q3b


embedded image








3-207
Q3b


embedded image








3-208
Q3b


embedded image








3-209
Q3b
CH2O(CH2)2NHSO2CH3



3-210
Q3b
CH2O(CH2)2N(CH3)(SO2CH3)






3-211
Q3b


embedded image








3-212
Q3b
CH2O(CH2)2NHSO2CF3



3-213
Q3b
CH2O(CH2)2NHSO2CHF2



3-214
Q3b
CH2O(CH2)2NHSO2CH2CF3



3-215
Q3b
SCH3



3-216
Q3b
SOCH3



3-217
Q3b
SO2CH3



3-218
Q3b
OCH3



3-219
Q3b
OCH2CH3



3-220
Q3b
O(CH2)2CH3



3-221
Q3b
OCH2CF3



3-222
Q3b
OCF2CF3



3-223
Q3b
O(CH2)2OCH3



3-224
Q3b
NHCH3



3-225
Q3b
NHCH2CH3



3-226
Q3b
N(CH3)2



3-227
Q3b
N(CH2CH3)2



3-228
Q3b
N(CH3)(CH2CH3)



3-229
Q3c
CH3



3-230
Q3c
CH2CH3



3-231
Q3c
(CH2)2CH3






3-232
Q3c


embedded image








3-233
Q3c


embedded image








3-234
Q3c


embedded image








3-235
Q3c


embedded image








3-236
Q3c


embedded image








3-237
Q3c


embedded image








3-238
Q3c


embedded image








3-239
Q3c


embedded image








3-240
Q3c
CF3





















TABLE 51










physical






property



compound


(melting



number
Q
R1

text missing or illegible when filed










3-241
Q3c
CH2CF3




3-242
Q3c
CF2CF3




3-243
Q3c
CH2CH═CH




3-244
Q3c
CH2C≡CH




3-245
Q3c
C6C5




3-246
Q3c
CH2C6C5




3-247
Q3c
CH2OCH3




3-248
Q3c
CH2OCH2CH3




3-249
Q3c
CH2O(CH2)2CH3




3-250
Q3c
(CH2)2OCH3




3-251
Q3c
(CH2)3OCH3








3-252
Q3c


embedded image










3-253
Q3c


embedded image










3-254
Q3c


embedded image










3-255
Q3c


embedded image










3-256
Q3c
CH2OCH2CF3




3-257
Q3c
CH2OCH2CHF2




3-258
Q3c
CH2OCH2CF2CF3




3-259
Q3c
CH2OCH2CH═CH2




3-260
Q3c
CH2OCH2CH═CCl2




3-261
Q3c
CH2OCH2CF═CF




3-262
Q3c
CH2OC2C≡CH




3-263
Q3c
CH2OCH2C≡CCH3




3-264
Q3c
CH2SCH3




3-265
Q3c
CH2S(CH2)2CH3




3-266
Q3c
CH2S(CH2)2CH3








3-267
Q3c


embedded image










3-268
Q3c


embedded image










3-269
Q3c


embedded image










3-270
Q3c


embedded image










3-271
Q3c
CH2SCH2CF3




3-272
Q3c
CH2SCH2CH═CH2




3-273
Q3c
CH2SCH2C≡CH




3-274
Q3c
CH2SOCH3




3-275
Q3c
CH2SOCH2CH3




3-276
Q3c
CH2SO(CH2)2CH3








3-277
Q3c


embedded image










3-278
Q3c


embedded image










3-279
Q3c


embedded image










3-280
Q3c


embedded image










text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 52








physical


com-


property


pound


(melting


number

text missing or illegible when filed

R1
point-ND)







3-281

text missing or illegible when filed 3c
CH2SOCHtext missing or illegible when filed CF3



3-282

text missing or illegible when filed 3c
CHtext missing or illegible when filed SOCH2CH═CHtext missing or illegible when filed



3-283

text missing or illegible when filed 3c
CHtext missing or illegible when filed SOCH2C═CH



3-284

text missing or illegible when filed 3c
CHtext missing or illegible when filed SOtext missing or illegible when filed CH2



3-285

text missing or illegible when filed 3c
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CH3



3-286

text missing or illegible when filed 3c
CHtext missing or illegible when filed SO2(CH2)2text missing or illegible when filed CHtext missing or illegible when filed






3-287

text missing or illegible when filed 3c


embedded image








3-288

text missing or illegible when filed 3c


embedded image








3-289

text missing or illegible when filed 3c


embedded image








3-290

text missing or illegible when filed 3c


embedded image








3-291

text missing or illegible when filed 3c
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed



3-292

text missing or illegible when filed 3c
CHtext missing or illegible when filed SOtext missing or illegible when filed CH2CH═CHtext missing or illegible when filed



3-293

text missing or illegible when filed 3c
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed C═CH



3-294

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CH2)text missing or illegible when filed OCH3



3-295

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed






3-296

text missing or illegible when filed 3c


embedded image








3-297

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CH2)2OCH2CFtext missing or illegible when filed



3-298

text missing or illegible when filed 3c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed CH2



3-299

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CH2)2OCH2CH═CH



3-300

text missing or illegible when filed 3c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed






3-301

text missing or illegible when filed 3c


embedded image








3-302

text missing or illegible when filed 3c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



3-303

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CH2)2SCHtext missing or illegible when filed CH═CHtext missing or illegible when filed



3-304

text missing or illegible when filed 3c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed C═CH



3-305

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CH2)2SOCHtext missing or illegible when filed






3-306

text missing or illegible when filed 3c


embedded image








3-307

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CH2)2SOCH2CFtext missing or illegible when filed



3-308

text missing or illegible when filed 3c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CH═CHtext missing or illegible when filed



3-309

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CH2)2SOCH2C═CH



3-310

text missing or illegible when filed 3c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed






3-311

text missing or illegible when filed 3c


embedded image








3-312

text missing or illegible when filed 3c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed



3-313

text missing or illegible when filed 3c
CHtext missing or illegible when filed O(CH2)2SOtext missing or illegible when filed CHtext missing or illegible when filed CH═CHtext missing or illegible when filed



3-314

text missing or illegible when filed 3c
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed C═CH






3-315

text missing or illegible when filed 3c


embedded image








3-316

text missing or illegible when filed 3c


embedded image








3-317

text missing or illegible when filed 3c


embedded image








3-318

text missing or illegible when filed 3c


embedded image








3-319

text missing or illegible when filed 3c


embedded image








3-320

text missing or illegible when filed 3c


embedded image








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 53








physical





property





(melting


compound


point-


number
Q
R1
ND)







3-321
Q3c


embedded image








3-322
Q3c


embedded image








3-323
Q3c
CH2O(CH2)2NHSO2CH3



3-324
Q3c
CH2O(CH2)2N(CH3)(SO2CH3)






3-325
Q3c


embedded image








3-326
Q3c
CH2O(CH2)2NHSO2CF3



3-327
Q3c
CH2O(CH2)2NHSO2CHF2



3-328
Q3c
CH2O(CH2)2NHSO2CH2CF3



3-329
Q3c
SCH3



3-330
Q3c
SOCH3



3-331
Q3c
SO2CH3



3-332
Q3c
OCH3



3-333
Q3c
OCH2CH3



3-334
Q3c
O(CH2)2CH3



3-335
Q3c
OCH2CF3



3-336
Q3c
OCF2CF3



3-337
Q3c
O(CH2)2OCH3



3-338
Q3c
NHCH3



3-339
Q3c
NHCH2CH3



3-340
Q3c
N(CH3)2



3-341
Q3c
N(CH2CH3)2



3-342
Q3c
N(CH3)(CH2CH3)



3-343
Q3d
CH3
NMR


3-344
Q3d
CH2CH3



3-345
Q3d
(CH2)2CH3






3-346
Q3d


embedded image








3-347
Q3d


embedded image








3-348
Q3d


embedded image








3-349
Q3d


embedded image








3-350
Q3d


embedded image








3-351
Q3d


embedded image








3-352
Q3d


embedded image








3-353
Q3d


embedded image








3-354
Q3d
CF3



3-355
Q3d
CH2CF3



3-356
Q3d
CF2CF3



3-357
Q3d
CH2CH═CH2



3-358
Q3d
CH2C≡CH



3-359
Q3d
C6H5



3-360
Q3d
CH2C6H5




















TABLE 54









physical






property






(melting



compound


point-



number
Q
R1
ND)







 
3-361
Q3d
CH2OCH3




3-362
Q3d
CH2OCH2CH3




3-363
Q3d
CH2O(CH2)2CH3




3-364
Q3d
(CH2)2OCH3




3-365
Q3d
(CH2)3OCH3







3-366
Q3d


embedded image









3-367
Q3d


embedded image









3-368
Q3d


embedded image









3-369
Q3d


embedded image









3-370
Q3d
CH2OCH2CF3




3-371
Q3d
CH2OCF2CHF2




3-372
Q3d
CH2OCH2CF2CF3




3-373
Q3d
CH2OCH2CH═CH2




3-374
Q3d
CH2OCH2CH═CCl2




3-375
Q3d
CH2OCH2CF═CF2




3-376
Q3d
CH2OC2C≡CH




3-377
Q3d
CH2OCH2C≡CCH3




3-378
Q3d
CH2SCH3




3-379
Q3d
CH2SCH2CH3




3-380
Q3d
CH2S(CH2)2CH3







3-381
Q3d


embedded image









3-382
Q3d


embedded image









3-383
Q3d


embedded image









3-384
Q3d


embedded image









3-385
Q3d
CH2SCH2CF3




3-386
Q3d
CH2SCH2CH═CH2




3-387
Q3d
CH2SCH2C≡CH




3-388
Q3d
CH2SOCH3




3-389
Q3d
CH2SOCH2CH3




3-390
Q3d
CH2SO(CH2)2CH3







3-391
Q3d


embedded image









3-392
Q3d


embedded image









3-393
Q3d


embedded image









3-394
Q3d


embedded image









3-395
Q3d
CH2SOCH2CF3




3-396
Q3d
CH2SOCH2CH═CH2




3-397
Q3d
CH2SOCH2C≡CH




3-398
Q3d
CH2SO2CH3




3-399
Q3d
CH2SO2CH2CH3




3-400
Q3d
CH2SO2(CH2)2CH3



















TABLE 55








physical





property





(melting


compound


point-


number

text missing or illegible when filed

Rtext missing or illegible when filed
ND)







3-401

text missing or illegible when filed 3d


embedded image








3-402

text missing or illegible when filed 3d


embedded image








3-403

text missing or illegible when filed 3d


embedded image








3-404

text missing or illegible when filed 3d


embedded image








3-405

text missing or illegible when filed 3d
CH2SOtext missing or illegible when filed CH2CF3



3-406

text missing or illegible when filed 3d
CH2SO2CHtext missing or illegible when filed CH═CHtext missing or illegible when filed



3-407

text missing or illegible when filed 3d
CH2SOtext missing or illegible when filed CH2C═C



3-408

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



3-409

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CH3






3-410

text missing or illegible when filed 3d


embedded image








3-411

text missing or illegible when filed 3d
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



3-412

text missing or illegible when filed 3d
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH═CH3



3-413

text missing or illegible when filed 3d
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2C═CH



3-414

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3






3-415

text missing or illegible when filed 3d


embedded image








3-416

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



3-417

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CH═CH3



3-418

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2C═CH



3-419

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3






3-420

text missing or illegible when filed 3d


embedded image








3-421

text missing or illegible when filed 3d
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



3-422

text missing or illegible when filed 3d
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CH═CH2



3-423

text missing or illegible when filed 3d
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2C═CH



3-424

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3






3-425

text missing or illegible when filed 3d


embedded image








3-426

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3



3-427

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2C═CHtext missing or illegible when filed



3-428

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CH2C═CH






3-429

text missing or illegible when filed 3d


embedded image








3-430

text missing or illegible when filed 3d


embedded image








3-431

text missing or illegible when filed 3d


embedded image








3-432

text missing or illegible when filed 3d


embedded image








3-433

text missing or illegible when filed 3d


embedded image








3-434

text missing or illegible when filed 3d


embedded image








3-435

text missing or illegible when filed 3d


embedded image








3-436

text missing or illegible when filed 3d


embedded image








3-437

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



3-438

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SOtext missing or illegible when filed CH3)






3-439

text missing or illegible when filed 3d


embedded image








3-440

text missing or illegible when filed 3d
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CF3






text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 56










physical






property



com-


(melting



pound


point-



number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)









3-441

text missing or illegible when filed 3d
CH2O(CH2)2NHSORtext missing or illegible when filed CHF3




3-442

text missing or illegible when filed 3d
CH2O(CH2)2NHSO2CHRtext missing or illegible when filed CF3




3-443

text missing or illegible when filed 3d
SCH3




3-444

text missing or illegible when filed 3d
SOCH3




3-445

text missing or illegible when filed 3d
SO2CH3




3-446

text missing or illegible when filed 3d
OCH3




3-447

text missing or illegible when filed 3d
OCH2CH3




3-448

text missing or illegible when filed 3d
O(CH2)text missing or illegible when filed CH3




3-449

text missing or illegible when filed 3d
OCH2CF3




3-450

text missing or illegible when filed 3d
OCF2CF3




3-451

text missing or illegible when filed 3d
O(CH2)text missing or illegible when filed OCH3




3-452

text missing or illegible when filed 3d
NHCH3




3-453

text missing or illegible when filed 3d
NHCHtext missing or illegible when filed CHtext missing or illegible when filed




3-454

text missing or illegible when filed 3d
N(CH3)2




3-455

text missing or illegible when filed 3d
N(CH2CH3)2




3-456

text missing or illegible when filed 3d
N(CH2)(CHtext missing or illegible when filed CH3)




3-457

text missing or illegible when filed 3e
CH3




3-458

text missing or illegible when filed 3e
CF3




3-459

text missing or illegible when filed 3e
(CH3)2CH3








3-460

text missing or illegible when filed 3e


embedded image










3-461

text missing or illegible when filed 3e


embedded image










3-462

text missing or illegible when filed 3e


embedded image










3-463

text missing or illegible when filed 3e


embedded image










3-464

text missing or illegible when filed 3e


embedded image










3-465

text missing or illegible when filed 3e


embedded image










3-466

text missing or illegible when filed 3e


embedded image










3-467

text missing or illegible when filed 3e


embedded image










3-468

text missing or illegible when filed 3e
CFtext missing or illegible when filed




3-469

text missing or illegible when filed 3e
CH2CFtext missing or illegible when filed




3-470

text missing or illegible when filed 3e
CF2CF3




4-471

text missing or illegible when filed 3e
CH2CH═CH3




4-472

text missing or illegible when filed 3e
CH2C═CH




4-473

text missing or illegible when filed 3e
Ctext missing or illegible when filed Htext missing or illegible when filed




4-474

text missing or illegible when filed 3e
CH2Ctext missing or illegible when filed Htext missing or illegible when filed




4-475

text missing or illegible when filed 3e
CH2OCH3




4-476

text missing or illegible when filed 3e
CH2OCH2CH3




4-477

text missing or illegible when filed 3e
CH2O(CH2)text missing or illegible when filed CH3




4-478

text missing or illegible when filed 3e
(CH2)2OCH3




4-479

text missing or illegible when filed 3e
(CHtext missing or illegible when filed )text missing or illegible when filed OCH3








4-480

text missing or illegible when filed 3e


embedded image










text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 57










physical






property



compound


(melting



number
Q
R1
point-ND)









3-481
Q3e


embedded image










3-482
Q3e


embedded image










3-483
Q3e


embedded image










3-484
Q3e
CH2OCH2CF3




3-485
Q3e





3-486
Q3e
CH2OCH2CF2CF3




3-487
Q3e
CH2OCH2CH═CH2




3-488
Q3e
CH2OCH2CH═CCl2




3-489
Q3e
CH2OCH2CF═CF2




3-490
Q3e
CH2OC2C≡CH




3-491
Q3e
CH2OCH2C≡CCH3




3-492
Q3e
CH2SCH3




3-493
Q3e
CH2SCH2CH3




3-494
Q3e
CH2S(CH2)2CH3








3-495
Q3e


embedded image










3-496
Q3e


embedded image










3-497
Q3e


embedded image










3-498
Q3e


embedded image










3-499
Q3e
CH2SCH2CF3




3-500
Q3e
CH2SCH2CH═CH2




3-501
Q3e
CH2SCH2C═CH




3-502
Q3e
CH2SOCH3




3-503
Q3e
CH2SOCH2CH3




3-504
Q3e
CH2SO(CH2)2CH3








3-505
Q3e


embedded image










3-506
Q3e


embedded image










3-507
Q3e


embedded image










3-508
Q3e


embedded image










3-509
Q3e
CH2SOCH2CF3




3-510
Q3e
CH2SOCH2CH═CH2




3-511
Q3e
CH2SOCH2C≡CH




3-512
Q3e
CH2SO2CH3




3-513
Q3e
CH2SO2CH2CH3




3-514
Q3e
CH2SO2(CH2)2CH3








3-515
Q3e


embedded image










3-516
Q3e


embedded image










3-517
Q3e


embedded image










3-518
Q3e


embedded image










3-519
Q3e
CH2SO2CH2CF3




3-520
Q3e
CH2SO2CH2CH═CH2




















TABLE 58








physical





property


compound


(melting


number
Q
R1
point-ND)







3-521
Q3e
CH2SO2CH2C≡CH



3-522
Q3e
CH2O(CH2)2OCH3



3-523
Q3e
CH2O(CH2)2OCH2CH3






3-524
Q3e


embedded image








3-525
Q3e
CH2O(CH2)2OCH2CF3



3-526
Q3e
CH2O(CH2)2OCH2CH═CH2



3-527
Q3e
CH2O(CH2)2OCH2C≡CH



3-528
Q3e
CH2O(CH2)2SCH3






3-529
Q3e


embedded image








3-530
Q3e
CH2O(CH2)2SCH2CF3



3-531
Q3e
CH2O(CH2)2SCH2CH═CH2



3-532
Q3e
CH2O(CH2)2SCH2C≡CH



3-533
Q3e
CH2O(CH2)2SOCH3






3-534
Q3e


embedded image








3-535
Q3e
CH2O(CH2)2SOCH2CF3



3-536
Q3e
CH2O(CH2)2SOCH2CH═CH2



3-537
Q3e
CH2O(CH2)2SOCH2C≡CH



3-538
Q3e
CH2O(CH2)2SO2CH3






3-539
Q3e


embedded image





3-540
Q3e
CH2O(CH2)2SO2CH2CF3



3-541
Q3e
CH2O(CH2)2SO2CH2CH═CH2



3-542
Q3e
CH2O(CH2)2SO2CH2C≡CH






3-543
Q3e


embedded image








3-544
Q3e


embedded image








3-545
Q3e


embedded image








3-546
Q3e


embedded image








3-547
Q3e


embedded image








3-548
Q3e


embedded image








3-549
Q3e


embedded image








3-550
Q3e


embedded image








3-551
Q3e
CH2O(CH2)2NHSO2CH3



3-552
Q3e
CH2O(CH2)2N(CH3)(SO2CH3)






3-553
Q3e


embedded image








3-554
Q3e
CH2O(CH2)2NHSO2CF3



3-555
Q3e
CH2O(CH2)2NHSO2CHF2



3-556
Q3e
CH2O(CH2)2NHSO2CH2CF3



3-557
Q3e
SCH3



3-558
Q3e
SOCH3



3-559
Q3e
SO2CH3



3-560
Q3e
OCH3




















TABLE 59









physical






property



compound


(melting



number
Q
R1
point-ND)








3-561
Q3e
OCH2CH3




3-562
Q3e
O(CH2)2CH3




3-563
Q3e
OCH2CF3




3-564
Q3e
OCF2CF3




3-565
Q3e
O(CH2)2OCH3




3-566
Q3e
NHCH3




3-567
Q3e
NHCH2CH3




3-568
Q3e
N(CH3)2




3-569
Q3e
N(CH2CH3)2




3-570
Q3e
N(CH3)(CH2CH3)




3-571
Q3f
CH3




3-572
Q3f
CH2CH3




3-573
Q3f
(CH2)2CH3







3-574
Q3f


embedded image









3-575
Q3f


embedded image









3-576
Q3f


embedded image









3-577
Q3f


embedded image









3-578
Q3f


embedded image









3-579
Q3f


embedded image









3-580
Q3f


embedded image









3-581
Q3f


embedded image









3-582
Q3f
CF3




3-583
Q3f
CH2CF3




3-584
Q3f
CF2CF3




3-585
Q3f
CH2CH═CH2




3-586
Q3f
CH2C≡CH




3-587
Q3f
C6H5




3-588
Q3f
CH2C6H5




3-589
Q3f
CH2OCH3




3-590
Q3f
CH2OCH2CH3




3-591
Q3f
CH2O(CH2)2CH3




3-592
Q3f
(CH2)2OCH3




3-593
Q3f
(CH2)3OCH3







3-594
Q3f


embedded image









3-595
Q3f


embedded image









3-596
Q3f


embedded image









3-597
Q3f


embedded image









3-598
Q3f
CH2OCH2CF3




3-599
Q3f
CH2OCF2CHF2




3-600
Q3f
CH2OCH2CF2CF3




















TABLE 60









physical






property






(melting



compound


point-



number
Q
R1
ND)







 
3-601
Q3f
CH2OCH2CH═CH2




3-602
Q3f
CH2OCH2CH═CCl2




3-603
Q3f
CH2OCH2CF═CF2




3-604
Q3f
CH2OC2C≡CH




3-605
Q3f
CH2OCH2C≡CCH3




3-606
Q3f
CH2SCH3




3-607
Q3f
CH2SCH2CH3




3-608
Q3f
CH2S(CH2)2CH3







3-609
Q3f


embedded image









3-610
Q3f


embedded image









3-611
Q3f


embedded image









3-612
Q3f


embedded image









3-613
Q3f
CH2SCH2CF3




3-614
Q3f
CH2SCH2CH═CH2




3-615
Q3f
CH2SCH2C≡CH




3-616
Q3f
CH2SOCH3




3-617
Q3f
CH2SOCH2CH3




3-618
Q3f
CH2SO(CH2)2CH3







3-619
Q3f


embedded image









3-620
Q3f


embedded image









3-621
Q3f


embedded image









3-622
Q3f


embedded image









3-623
Q3f
CH2SOCH2CF3




3-624
Q3f
CH2SOCH2CH═CH2




3-625
Q3f
CH2SOCH2C≡CH




3-626
Q3f
CH2SO2CH3




3-627
Q3f
CH2SO2CH2CH3




3-628
Q3f
CH2SO2(CH2)2CH3







3-629
Q3f


embedded image









3-630
Q3f


embedded image









3-631
Q3f


embedded image









3-632
Q3f


embedded image









3-633
Q3f
CH2SO2CH2CF3




3-634
Q3f
CH2SO2CH2CH═CH2




3-635
Q3f
CH2SO2CH2C≡CH




3-636
Q3f
CH2O(CH2)2OCH3




3-637
Q3f
CH2O(CH2)2OCH2CH3







3-638
Q3f


embedded image









3-639
Q3f
CH2O(CH2)2OCH2CF3




3-640
Q3f
CH2O(CH2)2OCH2CH═CH2



















TABLE 61








physical





property


compound


(melting


number
Q
R1
point-ND)







3-641
Q3f
CH2O(CH2)2OCH2C≡CH



3-642
Q3f
CH2O(CH2)2SCH3






3-643
Q3f


embedded image








3-644
Q3f
CH2O(CH2)2SCH2CF3



3-645
Q3f
CH2O(CH2)2SCH2CH═CH2



3-646
Q3f
CH2O(CH2)2SCH2C≡CH



3-647
Q3f
CH2O(CH2)2SOCH3






3-648
Q3f


embedded image








3-649
Q3f
CH2O(CH2)2SOCH2CF3



3-650
Q3f
CH2O(CH2)2SOCH2CH═CH2



3-651
Q3f
CH2O(CH2)2SOCH2C≡CH



3-652
Q3f
CH2O(CH2)2SO2CH3






3-653
Q3f


embedded image








3-654
Q3f
CH2O(CH2)2SO2CH2CF3



3-655
Q3f
CH2O(CH2)2SO2CH2CH═CH2



3-656
Q3f
CH2O(CH2)2SO2CH2C≡CH






3-657
Q3f


embedded image








3-658
Q3f


embedded image








3-659
Q3f


embedded image








3-660
Q3f


embedded image








3-661
Q3f


embedded image








3-662
Q3f


embedded image








3-663
Q3f


embedded image








3-664
Q3f


embedded image








3-665
Q3f
CH2O(CH2)2NHSO2CH3



3-666
Q3f
CH2O(CH2)2N(CH3)(SO2CH3)






3-667
Q3f


embedded image








3-668
Q3f
CH2O(CH2)2NHSO2CF3



3-669
Q3f
CH2O(CH2)2NHSO2CHF2



3-670
Q3f
CH2O(CH2)2NHSO2CH2CF3



3-671
Q3f
SCH3



3-672
Q3f
SOCH3



3-673
Q3f
SO2CH3



3-674
Q3f
OCH3



3-675
Q3f
OCH2CH3



3-676
Q3f
O(CH2)2CH3



3-677
Q3f
OCH2CF3



3-678
Q3f
OCF2CF3



3-679
Q3f
O(CH2)2OCH3



3-680
Q3f
NHCH3



















TABLE 62





compound


physical property


number
Q
R1
(melting point-ND)

















3-681
Q3f
NHCH2CH3


3-682
Q3f
N(CH3)2


3-683
Q3f
N(CH2CH3)2


3-684
Q3f
N(CH3)(CH2CH3)
















TABLE 63









embedded image














Q4a




embedded image









Q4b




embedded image



















physical





property


compound


(melting


number
Q
R1
point-ND)





4-1 
Q4a
CH3



4-2 
Q4a
CH2CH3



4-3 
Q4a
(CH2)2CH3






4-4 
Q4a


embedded image








4-5 
Q4a


embedded image








4-6 
Q4a


embedded image








4-7 
Q4a


embedded image








4-8 
Q4a


embedded image








4-9 
Q4a


embedded image








4-10
Q4a


embedded image








4-11
Q4a


embedded image








4-12
Q4a
CF3



4-13
Q4a
CH2CF3



4-14
Q4a
CF2CF3



4-15
Q4a
CH2CH═CH2



4-16
Q4a
CH2C≡CH



4-17
Q4a
C6H5



4-18
Q4a
CH2C6H5



4-19
Q4a
CH2OCH3



4-20
Q4a
CH2OCH2CH3



4-21
Q4a
CH2O(CH2)2CH3



4-22
Q4a
(CH2)2OCH3



4-23
Q4a
(CH2)3OCH3






4-24
Q4a


embedded image








4-25
Q4a


embedded image








4-26
Q4a


embedded image








4-27
Q4a


embedded image








4-28
Q4a
CH2OCH2CF3



4-29
Q4a
CH2OCF2CHF2



4-30
Q4a
CH2OCH2CF2CF3



4-31
Q4a
CH2OCH2CH═CH2



4-32
Q4a
CH2OCH2CH═CCl2



4-33
Q4a
CH2OCH2CF═CF2



4-34
Q4a
CH2OC2C≡CH



4-35
Q4a
CH2OCH2C≡CCH3



4-36
Q4a
CH2SCH3



4-37
Q4a
CH2SCH2CH3



4-38
Q4a
CH2S(CH2)2CH3






4-39
Q4a


embedded image








4-40
Q4a


embedded image





















TABLE 64








physical





property


compound


(melting


number
Q
R1
point-ND)







4-41
Q4a


embedded image








4-42
Q4a


embedded image








4-43
Q4a
CH2SCH2CF3



4-44
Q4a
CH2SCH2CH═CH2



4-45
Q4a
CH2SCH2C≡CH



4-46
Q4a
CH2SOCH3



4-47
Q4a
CH2SOCH2CH3



4-48
Q4a
CH2SO(CH2)2CH3






4-49
Q4a


embedded image








4-50
Q4a


embedded image








4-51
Q4a


embedded image








4-52
Q4a


embedded image








4-53
Q4a
CH2SOCH2CF3



4-54
Q4a
CH2SOCH2CH═CH2



4-55
Q4a
CH2SOCH2C≡CH



4-56
Q4a
CH2SO2CH3



4-57
Q4a
CH2SO2CH2CH3



4-58
Q4a
CH2SO2(CH2)2CH3






4-59
Q4a


embedded image








4-60
Q4a


embedded image








4-61
Q4a


embedded image








4-62
Q4a


embedded image








4-63
Q4a
CH2SO2CH2CF3



4-64
Q4a
CH2SO2CH2CH═CH2



4-65
Q4a
CH2SO2CH2C≡CH



4-66
Q4a
CH2O(CH2)2OCH3



4-67
Q4a
CH2O(CH2)2OCH2CH3






4-68
Q4a


embedded image








4-69
Q4a
CH2O(CH2)2OCH2CF3



4-70
Q4a
CH2O(CH2)2OCH2CH═CH2



4-71
Q4a
CH2O(CH2)2OCH2C≡CH



4-72
Q4a
CH2O(CH2)2SCH3






4-73
Q4a


embedded image








4-74
Q4a
CH2O(CH2)2SCH2CF3



4-75
Q4a
CH2O(CH2)2SCH2CH═CH2



4-76
Q4a
CH2O(CH2)2SCH2C≡CH



4-77
Q4a
CH2O(CH2)2SOCH3






4-78
Q4a


embedded image








4-79
Q4a
CH2O(CH2)2SOCH2CF3



4-80
Q4a
CH2O(CH2)2SOCH2CH═CH2



















TABLE 65








physical





property


compound


(melting


number
Q
R1
point-ND)







4-81 
Q4a
CH2O(CH2)2SOCH2C≡CH



4-82 
Q4a
CH2O(CH2)2SO2CH3






4-83 
Q4a


embedded image








4-84 
Q4a
CH2O(CH2)2SO2CH2CF3



4-85 
Q4a
CH2O(CH2)2SO2CH2CH═CH2



4-86 
Q4a
CH2O(CH2)2SO2CH2C≡CH






4-87 
Q4a


embedded image








4-88 
Q4a


embedded image








4-89 
Q4a


embedded image








4-90 
Q4a


embedded image








4-91 
Q4a


embedded image








4-92 
Q4a


embedded image








4-93 
Q4a


embedded image








4-94 
Q4a


embedded image








4-95 
Q4a
CH2O(CH2)2NHSO2CH3



4-96 
Q4a
CH2O(CH2)2N(CH3)(SO2CH3)






4-97 
Q4a


embedded image








4-98 
Q4a
CH2O(CH2)2NHSO2CF3



4-99 
Q4a
CH2O(CH2)2NHSO2CHF2



4-100
Q4a
CH2O(CH2)2NHSO2CH2CF3



4-101
Q4a
SCH3



4-102
Q4a
SOCH3



4-103
Q4a
SO2CH3



4-104
Q4a
OCH3



4-105
Q4a
OCH2CH3



4-106
Q4a
O(CH2)2CH3



4-107
Q4a
OCH2CF3



4-108
Q4a
OCF2CF3



4-109
Q4a
O(CH2)2OCH3



4-110
Q4a
NHCH3



4-111
Q4a
NHCH2CH3



4-112
Q4a
N(CH3)2



4-113
Q4a
N(CH2CH3)2



4-114
Q4a
N(CH3)(CH2CH3)



4-115
Q4b
CH3
NMR


4-116
Q4b
CH2CH3



4-117
Q4b
(CH2)2CH3






4-118
Q4b


embedded image








4-119
Q4b


embedded image








4-120
Q4b


embedded image





















TABLE 66








physical





property


compound


(melting


number
Q
R1
point-ND)







4-121
Q4b


embedded image








4-122
Q4b


embedded image








4-123
Q4b


embedded image








4-124
Q4b


embedded image








4-125
Q4b


embedded image








4-126
Q4b
CF3
122-132° C.


4-127
Q4b
CH2CF3



4-128
Q4b
CF2CF3



4-129
Q4b
CH2CH═CH2



4-130
Q4b
CH2C≡CH



4-131
Q4b
C6H5



4-132
Q4b
CH2C6H5



4-133
Q4b
CH2OCH3
1.5723(25)


4-134
Q4b
CH2OCH2CH3



4-135
Q4b
CH2O(CH2)2CH3



4-136
Q4b
(CH2)2OCH3



4-137
Q4b
(CH2)3OCH3






4-138
Q4b


embedded image








4-139
Q4b


embedded image








4-140
Q4b


embedded image








4-141
Q4b




4-142
Q4b
CH2OCH2CF3
NMR


4-143
Q4b
CH2OCF2CHF2



4-144
Q4b
CH2OCH2CF2CF3



4-145
Q4b
CH2OCH2CH═CH2



4-146
Q4b
CH2OCH2CH═CCl2



4-147
Q4b
CH2OCH2CF═CF2



4-148
Q4b
CH2OC2C≡CH



4-149
Q4b
CH2OCH2C≡CCH3



4-150
Q4b
CH2SCH3



4-151
Q4b
CH2SCH2CH3



4-152
Q4b
CH2S(CH2)2CH3






4-153
Q4b


embedded image








4-154
Q4b


embedded image








4-155
Q4b


embedded image








4-156
Q4b


embedded image








4-157
Q4b
CH2SCH2CF3



4-158
Q4b
CH2SCH2CH═CH2



4-159
Q4b
CH2SCH2C≡CH



4-160
Q4b
CH2SOCH3



















TABLE 67








physical





property


compound


(melting


number
Q
R1
point-ND)







4-161
Q4b
CH2SOCH2CH3



4-162
Q4b
CH2SO(CH2)2CH3






4-163
Q4b


embedded image








4-164
Q4b


embedded image








4-165
Q4b


embedded image








4-166
Q4b


embedded image








4-167
Q4b
CH2SOCH2CF3



4-168
Q4b
CH2SOCH2CH═CH2



4-169
Q4b
CH2SOCH2C≡CH



4-170
Q4b
CH2SO2CH3



4-171
Q4b
CH2SO2CH2CH3



4-172
Q4b
CH2SO2(CH2)2CH3






4-173
Q4b


embedded image








4-174
Q4b


embedded image








4-175
Q4b


embedded image








4-176
Q4b


embedded image








4-177
Q4b
CH2SO2CH2CF3



4-178
Q4b
CH2SO2CH2CH═CH2



4-179
Q4b
CH2SO2CH2C≡CH



4-180
Q4b
CH2O(CH2)2OCH3



4-181
Q4b
CH2O(CH2)2OCH2CH3






4-182
Q4b


embedded image








4-183
Q4b
CH2O(CH2)2OCH2CF3



4-184
Q4b
CH2O(CH2)2OCH2CH═CH2



4-185
Q4b
CH2O(CH2)2OCH2C≡CH



4-186
Q4b
CH2O(CH2)2SCH3






4-187
Q4b


embedded image








4-188
Q4b
CH2O(CH2)2SCH2CF3



4-189
Q4b
CH2O(CH2)2SCH2CH═CH2



4-190
Q4b
CH2O(CH2)2SCH2C≡CH



4-191
Q4b
CH2O(CH2)2SOCH3






4-192
Q4b


embedded image








4-193
Q4b
CH2O(CH2)2SOCH2CF3



4-194
Q4b
CH2O(CH2)2SOCH2CH═CH2



4-195
Q4b
CH2O(CH2)2SOCH2C≡CH



4-196
Q4b
CH2O(CH2)2SO2CH3






4-197
Q4b


embedded image








4-198
Q4b
CH2O(CH2)2SO2CH2CF3



4-199
Q4b
CH2O(CH2)2SO2CH2CH═CH2



4-200
Q4b
CH2O(CH2)2SO2CH2C≡CH



















TABLE 68








physical





property


compound


(melting


number
Q
R1
point-ND)







4-201
Q4b


embedded image








4-202
Q4b


embedded image








4-203
Q4b


embedded image








4-204
Q4b


embedded image








4-205
Q4b


embedded image








4-206
Q4b


embedded image








4-207
Q4b


embedded image








4-208
Q4b


embedded image








4-209
Q4b
CH2O(CH2)2NHSO2CH3



4-210
Q4b
CH2O(CH2)2 N(CH3)(SO2CH3)






4-211
Q4b


embedded image








4-212
Q4b
CH2O(CH2)2NHSO2CF3



4-213
Q4b
CH2O(CH2)2NHSO2CHF2



4-214
Q4b
CH2O(CH2)2NHSO2CH2CF3



4-215
Q4b
SCH3



4-216
Q4b
SOCH3



4-217
Q4b
SO2CH3



4-218
Q4b
OCH3



4-219
Q4b
OCH2CH3



4-220
Q4b
O(CH2)2CH3



4-221
Q4b
OCH2CF3



4-222
Q4b
OCF2CF3



4-223
Q4b
O(CH2)2OCH3



4-224
Q4b
NHCH3



4-225
Q4b
NHCH2CH3



4-226
Q4b
N(CH3)2



4-227
Q4b
N(CH2CH3)2



4-228
Q4b
N(CH3)(CH2CH3)
















TABLE 69









embedded image




















physical






property



compound


(melting



number
R4
R1
point-ND)







5-1 
Cl
CH3




5-2 
Cl
CF3




5-3 
Cl
CH2OCH3




5-4 
Cl
CH2OCH2CH3








5-5 
Cl


embedded image










5-6 
Cl
CH2OCH2CF3




5-7 
Cl
CH2SCH3




5-8 
Cl
CH2SCH2CH3








5-9 
Cl


embedded image










5-10
Cl
CH2SCH2CF3




5-11
Cl
CH2SOCH3




5-12
Cl
CH2SOCH2CH3








5-13
Cl


embedded image










5-14
Cl
CH2SOCH2CF3




5-15
Cl
CH2SO2CH3




5-16
Cl
CH2SO2CH2CH3








5-17
Cl


embedded image










5-18
Cl
CH2SO2CH2CF3




5-19
Cl
CH2O(CH2)2OCH3




5-20
Cl
CH2O(CH2)2OCH2CH3




5-21
Cl
CH2O(CH2)2OCH2CF3




5-22
Cl
CH2O(CH2)2SCH3




5-23
Cl
CH2O(CH2)2SCH2CF3




5-24
Cl
CH2O(CH2)2SOCH3




5-25
Cl
CH2O(CH2)2SOCH2CF3




5-26
Cl
CH2O(CH2)2SO2CH3




5-27
Cl
CH2O(CH2)2SO2CH2CF3








5-28
Cl


embedded image










5-29
Cl


embedded image










5-30
Cl
CH2O(CH2)2NHSO2CH3




5-31
Cl
CH2O(CH2)2N(CH3)(SO2CH3)




5-32
SCH3
CH3




5-33
SCH3
CF3




5-34
SCH3
CH2OCH3




5-35
SCH3
CH2OCH2CH3








5-36
SCH3


embedded image










5-37
SCH3
CH2OCH2CF3




5-38
SCH3
CH2SCH3




5-39
SCH3
CH2SCH2CH3








5-40
SCH3


embedded image






















TABLE 70








physical





property


compound


(melting


number
R4
R1
point-ND)







5-41
SCH3
CH2SCH2CF3



5-42
SCH3
CH2SOCH3



5-43
SCH3
CH2SOCH2CH3






5-44
SCH3


embedded image








5-45
SCH3
CH2SOCH2CF3



5-46
SCH3
CH2SO2CH3



5-47
SCH3
CH2SO2CH2CH3






5-48
SCH3


embedded image








5-49
SCH3
CH2SO2CH2CF3



5-50
SCH3
CH2O(CH2)2OCH3



5-51
SCH3
CH2O(CH2)2OCH2CH3



5-52
SCH3
CH2O(CH2)2OCH2CF3



5-53
SCH3
CH2O(CH2)2SCH3



5-54
SCH3
CH2O(CH2)2SCH2CF3



5-55
SCH3
CH2O(CH2)2SOCH3



5-56
SCH3
CH2O(CH2)2SOCH2CF3



5-57
SCH3
CH2O(CH2)2SO2CH3



5-58
SCH3
CH2O(CH2)2SO2CH2CF3






5-59
SCH3


embedded image








5-60
SCH3


embedded image








5-61
SCH3
CH2O(CH2)2NHSO2CH3



5-62
SCH3
CH2O(CH2)2N(CH3)(SO2CH3)



5-63
SCH2CH3
CH3



5-64
SCH2CH3
CF3



5-65
SCH2CH3
CH2OCH3



5-66
SCH2CH3
CH2OCH2CH3






5-67
SCH2CH3


embedded image








5-68
SCH2CH3
CH2OCH2CF3



5-69
SCH2CH3
CH2SCH3



5-70
SCH2CH3
CH2SCH2CH3






5-71
SCH2CH3


embedded image








5-72
SCH2CH3
CH2SCH2CF3



5-73
SCH2CH3
CH2SOCH3



5-74
SCH2CH3
CH2SOCH2CH3






5-75
SCH2CH3


embedded image








5-76
SCH2CH3
CH2SOCH2CF3



5-77
SCH2CH3
CH2SO2CH3



5-78
SCH2CH3
CH2SO2CH2CH3






5-79
SCH2CH3


embedded image








5-80
SCH2CH3
CH2SO2CH2CF3



















TABLE 71








physical





property


compound


(melting


number
R4
R1
point-ND)







5-81 
SCH2CH3
CH2O(CH2)2OCH3



5-82 
SCH2CH3
CH2O(CH2)2OCH2CH3



5-83 
SCH2CH3
CH2O(CH2)2OCH2CF3



5-84 
SCH2CH3
CH2O(CH2)2SCH3



5-85 
SCH2CH3
CH2O(CH2)2SCH2CF3



5-86 
SCH2CH3
CH2O(CH2)2SOCH3



5-87 
SCH2CH3
CH2O(CH2)2SOCH2CF3



5-88 
SCH2CH3
CH2O(CH2)2SO2CH3



5-89 
SCH2CH3
CH2O(CH2)2SO2CH2CF3






5-90 
SCH2CH3


embedded image








5-91 
SCH2CH3


embedded image








5-92 
SCH2CH3
CH2O(CH2)2NHSO2CH3



5-93 
SCH2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



5-94 
S(CH2)2CH3
CH3



5-95 
S(CH2)2CH3
CF3



5-96 
S(CH2)2CH3
CH2OCH3



5-97 
S(CH2)2CH3
CH2OCH2CH3






5-98 
S(CH2)2CH3


embedded image








5-99 
S(CH2)2CH3
CH2OCH2CF3



5-100
S(CH2)2CH3
CH2SCH3



5-101
S(CH2)2CH3
CH2SCH2CH3






5-102
S(CH2)2CH3


embedded image








5-103
S(CH2)2CH3
CH2SCH2CF3



5-104
S(CH2)2CH3
CH2SOCH3



5-105
S(CH2)2CH3
CH2SOCH2CH3






5-106
S(CH2)2CH3


embedded image








5-107
S(CH2)2CH3
CH2SOCH2CF3



5-108
S(CH2)2CH3
CH2SO2CH3



5-109
S(CH2)2CH3
CH2SO2CH2CH3






5-110
S(CH2)2CH3


embedded image








5-111
S(CH2)2CH3
CH2SO2CH2CF3



5-112
S(CH2)2CH3
CH2O(CH2)2OCH3



5-113
S(CH2)2CH3
CH2O(CH2)2OCH2CH3



5-114
S(CH2)2CH3
CH2O(CH2)2OCH2CF3



5-115
S(CH2)2CH3
CH2O(CH2)2SCH3



5-116
S(CH2)2CH3
CH2O(CH2)2SCH2CF3



5-117
S(CH2)2CH3
CH2O(CH2)2SOCH3



5-118
S(CH2)2CH3
CH2O(CH2)2SOCH2CF3



5-119
S(CH2)2CH3
CH2O(CH2)2SO2CH3



5-120
S(CH2)2CH3
CH2O(CH2)2SO2CH2CF3



















TABLE 72








physical





property


compound


(melting point-


number
R4
R1
ND)







5-121
S(CH2)2CH3


embedded image








5-122
S(CH2)2CH3


embedded image








5-123
S(CH2)2CH3
CH2O(CH2)2NHSO2CH3



5-124
S(CH2)2CH3
CH2O(CH2)2N(CH3)SO2(CH3)



5-125
SC6H5
CH3



5-126
SC6H5
CF3



5-127
SC6H5
CH2OCH3



5-128
SC6H5
CH2OCH2CH3






5-129
SC6H5


embedded image








5-130
SC6H5
CH2OCH2CF3



5-131
SC6H5
CH2SCH3



5-132
SC6H5
CH2SCH2CH3






5-133
SC6H5


embedded image








5-134
SC6H5
CH2SCH2CF3



5-135
SC6H5
CH2SOCH3



5-136
SC6H5
CH2SOCH2CH3






5-137
SC6H5


embedded image








5-138
SC6H5
CH2SOCH2CF3



5-139
SC6H5
CH2SO2CH3



5-140
SC6H5
CH2SO2CH2CH3






5-141
SC6H5


embedded image








5-142
SC6H5
CH2SO2CH2CF3



5-143
SC6H5
CH2O(CH2)2OCH3



5-144
SC6H5
CH2O(CH2)2OCH2CH3



5-145
SC6H5
CH2O(CH2)2OCH2CF3



5-146
SC6H5
CH2O(CH2)2SCH3



5-147
SC6H5
CH2O(CH2)2SCH2CF3



5-148
SC6H5
CH2O(CH2)2SOCH3



5-149
SC6H5
CH2O(CH2)2SOCH2CF3



5-150
SC6H5
CH2O(CH2)2SO2CH3



5-151
SC6H5
CH2O(CH2)2SO2CH2CF3






5-152
SC6H5


embedded image








5-153
SC6H5


embedded image








5-154
SC6H5
CH2O(CH2)2NHSO2CH3



5-155
SC6H5
CH2O(CH2)2N(CH3)(SO2CH3)



5-156
SCH2C6H5
CH3



5-157
SCH2C6H5
CF3



5-158
SCH2C6H5
CH2OCH3



5-159
SCH2C6H5
CH2OCH2CH3






5-160
SCH2C6H5


embedded image





















TABLE 73








physical





property


compound


(melting point-


number
R4
R1
ND)







5-161
SCH2C6H5
CH2OCH2CF3



5-162
SCH2C6H5
CH2SCH3



5-163
SCH2C6H5
CH2SCH2CH3






5-164
SCH2C6H5


embedded image








5-165
SCH2C6H5
CH2SCH2CF3



5-166
SCH2C6H5
CH2SOCH3



5-167
SCH2C6H5
CH2SOCH2CH3






5-168
SCH2C6H5


embedded image








5-169
SCH2C6H5
CH2SOCH2CF3



5-170
SCH2C6H5
CH2SO2CH3



5-171
SCH2C6H5
CH2SO2CH2CH3






5-172
SCH2C6H5


embedded image








5-173
SCH2C6H5
CH2SO2CH2CF3



5-174
SCH2C6H5
CH2O(CH2)2OCH3



5-175
SCH2C6H5
CH2O(CH2)2OCH2CH3



5-176
SCH2C6H5
CH2O(CH2)2OCH2CF3



5-177
SCH2C6H5
CH2O(CH2)2SCH3



5-178
SCH2C6H5
CH2O(CH2)2SCH2CF3



5-179
SCH2C6H5
CH2O(CH2)2SOCH3



5-180
SCH2C6H5
CH2O(CH2)2SOCH2CF3



5-181
SCH2C6H5
CH2O(CH2)2SO2CH3



5-182
SCH2C6H5
CH2O(CH2)2SO2CH2CF3






5-183
SCH2C6H5


embedded image








5-184
SCH2C6H5


embedded image








5-185
SCH2C6H5
CH2O(CH2)2NHSO2CH3



5-186
SCH2C6H5
CH2O(CH2)2N(CH3)(SO2CH3)



5-187
1H- text missing or illegible when filed -
CH3





text missing or illegible when filed -





1- text missing or illegible when filed




5-188
1H- text missing or illegible when filed -
CF3





text missing or illegible when filed -





1- text missing or illegible when filed




5-189
1H- text missing or illegible when filed -
CH2OCH3





text missing or illegible when filed -





1- text missing or illegible when filed




5-190
1H- text missing or illegible when filed -
CH2OCH2CH3





text missing or illegible when filed -





1- text missing or illegible when filed







5-191
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-192
1H- text missing or illegible when filed -
CH2OCH2CF3





text missing or illegible when filed -





1- text missing or illegible when filed




5-193
1H- text missing or illegible when filed -
CH2SCH3





text missing or illegible when filed -





1- text missing or illegible when filed




5-194
1H- text missing or illegible when filed -
CH2SCH2CH3





text missing or illegible when filed -





1- text missing or illegible when filed







5-195
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-196
1H- text missing or illegible when filed -
CH2SCH2CF3





text missing or illegible when filed -





1- text missing or illegible when filed




5-197
1H- text missing or illegible when filed -
CH2SOCH3





text missing or illegible when filed -





1- text missing or illegible when filed




5-198
1H- text missing or illegible when filed -
CH2SOCH2CH3





text missing or illegible when filed -





1- text missing or illegible when filed







5-199
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-200
1H- text missing or illegible when filed -
CH2SOCH2CF3





text missing or illegible when filed -





1- text missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 74








physical





property





(melting


compound


point-


number
R4
R1
ND)







5-201
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SO2CH3




1- text missing or illegible when filed




5-202
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SO2CH2CH3




1- text missing or illegible when filed







5-203
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-204
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SO2CH2CF3




1- text missing or illegible when filed




5-205
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2OCH3




1- text missing or illegible when filed




5-206
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2OCH2CH3




1- text missing or illegible when filed




5-207
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2OCH2CF3




1- text missing or illegible when filed




5-208
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2SCH3




1- text missing or illegible when filed




5-209
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2SCH2CF3




1- text missing or illegible when filed




5-210
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2SOCH3




1- text missing or illegible when filed




5-211
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2SOCH2CF3




1- text missing or illegible when filed




5-212
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2SO2CH3




1- text missing or illegible when filed




5-213
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2SO2CH2CF3




1- text missing or illegible when filed







5-214
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-215
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-216
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2NHSO2CH3




1- text missing or illegible when filed




5-217
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2N(CH3)(SO2CH3)




1- text missing or illegible when filed




5-218
1H- text missing or illegible when filed - text missing or illegible when filed -
CH3




1- text missing or illegible when filed




5-219
1H- text missing or illegible when filed - text missing or illegible when filed -
CF3




1- text missing or illegible when filed




5-220
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2OCH3




1- text missing or illegible when filed




5-221
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2OCH2CH3




1- text missing or illegible when filed







5-222
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-223
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2OCH2CF3




1- text missing or illegible when filed




5-224
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SCH3




1- text missing or illegible when filed




5-225
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SCH2CH3




1- text missing or illegible when filed







5-226
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-227
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SCH2CF3




1- text missing or illegible when filed




5-228
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SOCH3




1- text missing or illegible when filed




5-229
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SOCH2CH3




1- text missing or illegible when filed







5-230
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-231
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SOCH2CF3




1- text missing or illegible when filed




5-232
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SO2CH3




1- text missing or illegible when filed




5-233
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SO2CH2CH3




1- text missing or illegible when filed







5-234
1H- text missing or illegible when filed - text missing or illegible when filed - 1- text missing or illegible when filed


embedded image








5-235
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2SO2CH2CF3




1- text missing or illegible when filed




5-236
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2OCH3




1- text missing or illegible when filed




5-237
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2OCH2CH3




1- text missing or illegible when filed




5-238
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2OCH2CF3




1- text missing or illegible when filed




5-239
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2SCH3




1- text missing or illegible when filed




5-240
1H- text missing or illegible when filed - text missing or illegible when filed -
CH2O(CH2)2SCH2CF3




1- text missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 75








physical


com-


property


pound


(melting


num-


point-


ber
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







5-text missing or illegible when filed -41
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



5-text missing or illegible when filed -42
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



5-text missing or illegible when filed -43
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



5-text missing or illegible when filed -44
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






5-text missing or illegible when filed -45
1H-imidazole1-yl


embedded image








5-text missing or illegible when filed -46
1H-imidazole-1-yl


embedded image








5-text missing or illegible when filed -47
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



5-text missing or illegible when filed -48
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SO2CH3)



5-text missing or illegible when filed -49
1H-triazole-1-yl
CH3



5-text missing or illegible when filed -50
1H-triazole-1-yl
CF3



5-text missing or illegible when filed -51
1H-triazole-1-yl
CH2OCH3



5-text missing or illegible when filed -52
1H-triazole-1-yl
CH2OCH2CH3






5-text missing or illegible when filed -53
1H-triazole-1-yl


embedded image








5-text missing or illegible when filed -54
1H-triazole-1-yl
CH2OCH2CF3



5-text missing or illegible when filed -55
1H-triazole-1-yl
CH2SCH3



5-text missing or illegible when filed -56
1H-triazole-1-yl
CH2SCH2CH3






5-text missing or illegible when filed -57
1H-triazole-1-yl


embedded image








5-text missing or illegible when filed -58
1H-triazole-1-yl
CH2SCH2CF3



5-text missing or illegible when filed -59
1H-triazole-1-yl
CH2SOCH3



5-text missing or illegible when filed -60
1H-triazole-1-yl
CH2SOCH2CH3






5-text missing or illegible when filed -61
1H-triazole-1-yl


embedded image








5-text missing or illegible when filed -62
1H-triazole-1-yl
CH2SOCH2CF3



5-text missing or illegible when filed -63
1H-triazole-1-yl
CH2SO2CH3



5-text missing or illegible when filed -64
1H-triazole-1-yl
CH2SO2CH2CH3






5-text missing or illegible when filed -65
1H-triazole-1-yl


embedded image








5-text missing or illegible when filed -66
1H-triazole-1-yl
CH2SO2CH2CF3



5-text missing or illegible when filed -67
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



5-text missing or illegible when filed -68
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



5-text missing or illegible when filed -69
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



5-text missing or illegible when filed -70
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



5-text missing or illegible when filed -71
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



5-text missing or illegible when filed -72
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



5-text missing or illegible when filed -73
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



5-text missing or illegible when filed -74
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



5-text missing or illegible when filed -75
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






5-text missing or illegible when filed -76
1H-triazole-1-yl


embedded image








5-text missing or illegible when filed -77
1H-triazole-1-yl


embedded image








5-text missing or illegible when filed -78
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



5-text missing or illegible when filed -79
1H-triazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )SO2CH3)



5-text missing or illegible when filed -80
1H-tetrazole-1-yl
CH3






text missing or illegible when filed indicates data missing or illegible when filed






















physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







5-281
1H-tetrazole-1-yl
CF3



5-282
1H-tetrazole-1-yl
CH2CH3



5-283
1H-tetrazole-1-yl
CH2OCH2CH3






5-284
1H-tetrazole-1-yl


embedded image








5-285
1H-tetrazole-1-yl
CH2OCH2CF3



5-286
1H-tetrazole-1-yl
CH2SCH3



5-287
1H-tetrazole-1-yl
CH2SCH2CH3






5-288
1H-tetrazole-1-yl


embedded image








5-289
1H-tetrazole-1-yl
CH2SCH2CF3



5-290
1H-tetrazole-1-yl
CH2SOCH3



5-291
1H-tetrazole-1-yl
CH2SO2CH3






5-292
1H-tetrazole-1-yl


embedded image








5-293
1H-tetrazole-1-yl
CH2SOCH2CF3



5-294
1H-tetrazole-1-yl
CH2SO2CH3



5-295
1H-tetrazole-1-yl
CH2SO2CH2CH3






5-296
1H-tetrazole-1-yl


embedded image








5-297
1H-tetrazole-1-yl
CH2SO2CH2CF3



5-298
1H-tetrazole-1-yl
CH2CH(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



5-299
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH2



5-300
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



5-301
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



5-302
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



5-303
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



5-304
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



5-305
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



5-306
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






5-307
1H-tetrazole-1-yl


embedded image








5-308
1H-tetrazole-1-yl


embedded image








5-309
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



5-310
1H-tetrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SO2CH3)



5-311
1H-tetrazole-2-yl
CH3



5-312
1H-tetrazole-2-yl
CF3



5-313
1H-tetrazole-2-yl
OCH2CH3



5-314
1H-tetrazole-2-yl
CH2OCH2CH3






5-315
1H-tetazole-2-yl


embedded image








5-316
1H-tetrazole-2-yl
CH2OCH2CF3



5-317
1H-tetrazole-2-yl
CH2SCH3



5-318
1H-tetrazole-2-yl
CH2SCH2CH3






5-319
1H-tetrazole-2-yl


embedded image








5-320
1H-tetrazole-2-yl
CH2SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 77








physical


com-


property


pound


(melting


num-


point-


ber
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -321
1H-tetrazol-2-yl
CH2SOCH3




text missing or illegible when filed -322
1H-tetrazol-2-yl
CH2SOCH2CH3







text missing or illegible when filed -323
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -324
1H-tetrazol-2-yl
CH2SOCH2CF3




text missing or illegible when filed -325
1H-tetrazol-2-yl
CH2SO2CH3




text missing or illegible when filed -326
1H-tetrazol-2-yl
CH2SO2CH2CH3







text missing or illegible when filed -327
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -328
1H-tetrazol-2-yl
CH2SO2CH2CF3




text missing or illegible when filed -329
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -330
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -331
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -332
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -333
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3




text missing or illegible when filed -334
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -335
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CH3




text missing or illegible when filed -336
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -337
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3







text missing or illegible when filed -338
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -339
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -340
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




text missing or illegible when filed -341
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filedtext missing or illegible when filed SO2CHtext missing or illegible when filed )






text missing or illegible when filed indicates data missing or illegible when filed













TABLE 78









embedded image




















physical






property






(melting



compound


point-



number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -1
Cl
CH3





text missing or illegible when filed -2
Cl
CF3





text missing or illegible when filed -3
Cl
CH2OCH3





text missing or illegible when filed -4
Cl
CH2OCH2CH3









text missing or illegible when filed -5
Cl


embedded image











text missing or illegible when filed -6
Cl
CH2OCH2CF3





text missing or illegible when filed -7
Cl
CH2SCH3





text missing or illegible when filed -8
Cl
CH2SCH2CH3









text missing or illegible when filed -9
Cl


embedded image











text missing or illegible when filed -10
Cl
CH2SCH2CF3





text missing or illegible when filed -11
Cl
CH2SOCH3





text missing or illegible when filed -12
Cl
CH2SOCH2CH3









text missing or illegible when filed -13
Cl


embedded image











text missing or illegible when filed -14
Cl
CH2SOCH2CF3





text missing or illegible when filed -15
Cl
CH2SO2CH3





text missing or illegible when filed -16
Cl
CH2SO2CH2CH3









text missing or illegible when filed -17
Cl


embedded image











text missing or illegible when filed -18
Cl
CH2SO2CH2CF3





text missing or illegible when filed -19
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3





text missing or illegible when filed -20
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3





text missing or illegible when filed -21
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3





text missing or illegible when filed -22
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3





text missing or illegible when filed -23
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CH3





text missing or illegible when filed -24
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3





text missing or illegible when filed -25
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed CH2CF3





text missing or illegible when filed -26
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3





text missing or illegible when filed -27
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed CH2CF3









text missing or illegible when filed -28
Cl


embedded image











text missing or illegible when filed -29
Cl


embedded image











text missing or illegible when filed -30
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed SO2CH3









text missing or illegible when filed -31
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed (SO2CHtext missing or illegible when filed )





text missing or illegible when filed -32
SCH3
CH3





text missing or illegible when filed -33
SCH3
CF3





text missing or illegible when filed -34
SCH3
CH2OCH3





text missing or illegible when filed -35
SCH3
CH2OCH2CH3









text missing or illegible when filed -36
SCH3


embedded image











text missing or illegible when filed -37
SCH3
CH2OCH2CF3





text missing or illegible when filed -38
SCH3
CH2SCH3





text missing or illegible when filed -39
SCH3
CH2SCH2CH3









text missing or illegible when filed -40
SCH3


embedded image










text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 79








physical





property





(melting


compound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -41
SCH3
CH2OCH2CF3




text missing or illegible when filed -42
SCH3
CH2SOCH3




text missing or illegible when filed -43
SCH3
CH2SOCH2CH3







text missing or illegible when filed -44
SCH3


embedded image









text missing or illegible when filed -45
SCH3
CH2SOCH2CF3




text missing or illegible when filed -46
SCH3
CH2SO2CH3




text missing or illegible when filed -47
SCH3
CH2SO2CH2CH3







text missing or illegible when filed -48
SCH3


embedded image









text missing or illegible when filed -49
SCH3
CH2SO2CH2CH3




text missing or illegible when filed -50
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -51
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -52
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -53
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -54
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3




text missing or illegible when filed -55
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -56
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




text missing or illegible when filed -57
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -58
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3







text missing or illegible when filed -59
SCH3


embedded image









text missing or illegible when filed -60
SCH3


embedded image









text missing or illegible when filed -61
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




text missing or illegible when filed -62
SCH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed (SO2CHtext missing or illegible when filed )




text missing or illegible when filed -63
SCH2CH3
CH3




text missing or illegible when filed -64
SCH2CH3
CF3




text missing or illegible when filed -65
SCH2CH3
CH2OCH3




text missing or illegible when filed -66
SCH2CH3
CH2OCH2CH3







text missing or illegible when filed -67
SCH2CH3


embedded image









text missing or illegible when filed -68
SCH2CH3
CH2OCH2CF3




text missing or illegible when filed -69
SCH2CH3
CH2SCH3




text missing or illegible when filed -70
SCH2CH3
CH2SCH2CH3







text missing or illegible when filed -71
SCH2CH3


embedded image









text missing or illegible when filed -72
SCH2CH3
CH2SCH2CF3




text missing or illegible when filed -73
SCH2CH3
CH2SOCH3




text missing or illegible when filed -74
SCH2CH3
CH2SOCH2CH3







text missing or illegible when filed -75
SCH2CH3


embedded image









text missing or illegible when filed -76
SCH2CH3
CH2SOCH2CF3




text missing or illegible when filed -77
SCH2CH3
CH2SO2CH3




text missing or illegible when filed -78
SCH2CH3
CH2SO2CH2CH3




text missing or illegible when filed -79
SCH2CH3


embedded image









text missing or illegible when filed -80
SCH2CH3
CH2SO2CH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 80








physical





property





(melting


compound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -81
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -82
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -83
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -84
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -85
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3




text missing or illegible when filed -86
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -87
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




text missing or illegible when filed -88
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -89
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3







text missing or illegible when filed -90
SCH2CH3


embedded image









text missing or illegible when filed -91
SCH2CH3


embedded image









text missing or illegible when filed -92
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




text missing or illegible when filed -93
SCH2CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed Ntext missing or illegible when filedtext missing or illegible when filed SO2CH3)




text missing or illegible when filed -94
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH3




text missing or illegible when filed -95
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CF3




text missing or illegible when filed -96
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2OCH3




text missing or illegible when filed -97
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2OCH2CH3







text missing or illegible when filed -98
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3


embedded image









text missing or illegible when filed -99
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2OCH2CF3




text missing or illegible when filed -100
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SCH3




text missing or illegible when filed -101
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SCH2CH3







text missing or illegible when filed -102
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3


embedded image









text missing or illegible when filed -103
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SCH2CF3




text missing or illegible when filed -104
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SOCH3




text missing or illegible when filed -105
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SOCH2CH3







text missing or illegible when filed -106
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3


embedded image









text missing or illegible when filed -107
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SOCH2CF3




text missing or illegible when filed -108
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SO2CH3




text missing or illegible when filed -109
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SO2CH2CH3







text missing or illegible when filed -110
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3


embedded image









text missing or illegible when filed -111
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2SO2CH2CF3




text missing or illegible when filed -112
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -113
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -114
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -115
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -116
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed CH2CF3




text missing or illegible when filed -117
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -118
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




text missing or illegible when filed -119
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -120
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 81








physical


com-


property


pound


(melting


num-


point-


ber
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -121
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3


embedded image









text missing or illegible when filed -122
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3


embedded image









text missing or illegible when filed -123
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




text missing or illegible when filed -124
S(CHtext missing or illegible when filed )text missing or illegible when filed CH3
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )text missing or illegible when filed SO2CHtext missing or illegible when filed )




text missing or illegible when filed -125
SCtext missing or illegible when filed Htext missing or illegible when filed
CH3




text missing or illegible when filed -126
SCtext missing or illegible when filed Htext missing or illegible when filed
CF3




text missing or illegible when filed -127
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2OCH3




text missing or illegible when filed -128
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2OCH2CH3







text missing or illegible when filed -129
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -130
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2OCH2CF3




text missing or illegible when filed -131
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SCH3




text missing or illegible when filed -132
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SCH2CH3







text missing or illegible when filed -133
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -134
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SCH2CF3




text missing or illegible when filed -135
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2OCH3




text missing or illegible when filed -136
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH2CH3







text missing or illegible when filed -137
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -138
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH2CF3




text missing or illegible when filed -139
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH3




text missing or illegible when filed -140
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH2CH3







text missing or illegible when filed -141
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -142
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH2CF3




text missing or illegible when filed -143
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -144
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -145
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -146
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -147
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CH3




text missing or illegible when filed -148
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -149
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




text missing or illegible when filed -150
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -151
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3







text missing or illegible when filed -152
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -153
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -154
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




text missing or illegible when filed -155
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SO2CHtext missing or illegible when filed )




text missing or illegible when filed -156
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH3




text missing or illegible when filed -157
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CF3




text missing or illegible when filed -158
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH2OCH3




text missing or illegible when filed -159
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH2OCH2CH3







text missing or illegible when filed -160
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 82








physical


com-


property


pound


(melting


num-


point-


ber
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -161
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2OCH2CF3




text missing or illegible when filed -162
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SCH3




text missing or illegible when filed -163
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SCH2CH3







text missing or illegible when filed -164
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -165
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SCH2CF3




text missing or illegible when filed -166
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH3




text missing or illegible when filed -167
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH2CH3







text missing or illegible when filed -168
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -169
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH2CF3




text missing or illegible when filed -170
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH3




text missing or illegible when filed -171
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH2CH3







text missing or illegible when filed -172
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -173
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH2CF3




text missing or illegible when filed -174
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -175
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -176
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -177
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -178
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3




text missing or illegible when filed -179
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -180
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




text missing or illegible when filed -181
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -182
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3







text missing or illegible when filed -183
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -184
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image









text missing or illegible when filed -185
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




text missing or illegible when filed -186
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed SO2CHtext missing or illegible when filed )




text missing or illegible when filed -187
1H-pyrazole-1-yl
CH3




text missing or illegible when filed -188
1H-pyrazole-1-yl
CF3




text missing or illegible when filed -189
1H-pyrazole-1-yl
CH2OCH3




text missing or illegible when filed -190
1H-pyrazole-1-yl
CH2OCH2CH3







text missing or illegible when filed -191
1H-pyrazole-1-yl


embedded image









text missing or illegible when filed -192
1H-pyrazole-1-yl
CH2OCH2CF3




text missing or illegible when filed -193
1H-pyrazole-1-yl
CH2SCH3




text missing or illegible when filed -194
1H-pyrazole-1-yl
CH2SCH2CH3







text missing or illegible when filed -195
1H-pyrazole-1-yl


embedded image









text missing or illegible when filed -196
1H-pyrazole-1-yl
CH2SCH2CF3




text missing or illegible when filed -197
1H-pyrazole-1-yl
CH2SOCH3




text missing or illegible when filed -198
1H-pyrazole-1-yl
CH2SOCH2CH3







text missing or illegible when filed -199
1H-pyrazole-1-yl


embedded image









text missing or illegible when filed -200
1H-pyrazole-1-yl
CH2SOCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 83








phys-





ical


\


prop-





erty


com-


(melt-


pound


ing


num-


point-


ber
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -201
1H-pyrazole-1-yl
CH2SO2CH3




text missing or illegible when filed -202
1H-pyrazole-1-yl
CH2SO2CH2CH3







text missing or illegible when filed -203
1H-pyrazole-1-yl


embedded image









text missing or illegible when filed -204
1H-pyrazole-1-yl
CH2SO2CH2CF3




text missing or illegible when filed -205
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -206
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -207
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -208
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -209
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3




text missing or illegible when filed -210
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -211
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




text missing or illegible when filed -212
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -213
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3







text missing or illegible when filed -214
1H-pyrazole-1-yl


embedded image









text missing or illegible when filed -215
1H-pyrazole-1-yl


embedded image









text missing or illegible when filed -216
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




text missing or illegible when filed -217
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed SO2CHtext missing or illegible when filed )




text missing or illegible when filed -218
1H-imidazole-1-yl
CH3




text missing or illegible when filed -219
1H-imidazole-1-yl
CF3




text missing or illegible when filed -220
1H-imidazole-1-yl
OCH2CH3




text missing or illegible when filed -221
1H-imidazole-1-yl
CH2OCH2CH3







text missing or illegible when filed -222
1H-imidazole-1-yl


embedded image









text missing or illegible when filed -223
1H-imidazole-1-yl
CH2OCH2CF3




text missing or illegible when filed -224
1H-imidazole-1-yl
CH2SCH3




text missing or illegible when filed -225
1H-imidazole-1-yl
CH2SCH2CH3







text missing or illegible when filed -226
1H-imidazole-1-yl


embedded image









text missing or illegible when filed -227
1H-imidazole-1-yl
CH2SCH2CF3




text missing or illegible when filed -228
1H-imidazole-1-yl
SOCH3




text missing or illegible when filed -229
1H-imidazole-1-yl
CH2SOCH2CH3







text missing or illegible when filed -230
1H-imidazole-1-yl


embedded image









text missing or illegible when filed -231
1H-imidazole-1-yl
CH2SOCH2Ctext missing or illegible when filed




text missing or illegible when filed -232
1H-imidazole-1-yl
CH2SO2CH3




text missing or illegible when filed -233
1H-imidazole-1-yl
CH2SO2CH2CH3







text missing or illegible when filed -234
1H-imidazole-1-yl


embedded image









text missing or illegible when filed -235
1H-imidazole-1-yl
CH2SO2CH2CF3




text missing or illegible when filed -236
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -237
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -238
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -239
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -240
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 84










physical






property



compound


(melting



number
R4
R1
point-ND)










text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed



embedded image



text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed



embedded image



text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed



embedded image



text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed



embedded image



text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed



embedded image



text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed



embedded image



text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed



embedded image



text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed



embedded image



text missing or illegible when filed









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 85








physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -281
1H-tetrazol-1-yl
CF3




text missing or illegible when filed -282
1H-tetrazol-1-yl
CH2OCH3




text missing or illegible when filed -283
1H-tetrazol-1-yl
CH2OCH2OCH3







text missing or illegible when filed -284
1H-tetrazol-1-yl


embedded image









text missing or illegible when filed -285
1H-tetrazol-1-yl
CH2OCH2CF3




text missing or illegible when filed -286
1H-tetrazol-1-yl
CH2SCH3




text missing or illegible when filed -287
1H-tetrazol-1-yl
CH2SCH2CH3







text missing or illegible when filed -288
1H-tetrazol-1-yl


embedded image









text missing or illegible when filed -289
1H-tetrazol-1-yl
CH2SCH2CF3




text missing or illegible when filed -290
1H-tetrazol-1-yl
CH2SOCH3




text missing or illegible when filed -291
1H-tetrazol-1-yl
CH2SOCH2CH3







text missing or illegible when filed -292
1H-tetrazol-1-yl


embedded image









text missing or illegible when filed -293
1H-tetrazol-1-yl
CH2SOCH2CF3




text missing or illegible when filed -294
1H-tetrazol-1-yl
CH2SO2CH3




text missing or illegible when filed -295
1H-tetrazol-1-yl
CH2SO2CH2CH3







text missing or illegible when filed -296
1H-tetrazol-1-yl


embedded image









text missing or illegible when filed -297
1H-tetrazol-1-yl
CH2SO2CH2CF3




text missing or illegible when filed -298
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -299
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -300
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -301
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -302
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3




text missing or illegible when filed -303
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -304
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




text missing or illegible when filed -305
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -306
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3







text missing or illegible when filed -307
1H-tetrazol-1-yl


embedded image









text missing or illegible when filed -308
1H-tetrazol-1-yl


embedded image









text missing or illegible when filed -309
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




text missing or illegible when filed -310
1H-tetrazol-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3)




text missing or illegible when filed -311
1H-tetrazol-2-yl
CH3




text missing or illegible when filed -312
1H-tetrazol-2-yl
CF3




text missing or illegible when filed -313
1H-tetrazol-2-yl
CH2OCH3




text missing or illegible when filed -314
1H-tetrazol-2-yl
CH2OCH2CH3







text missing or illegible when filed -315
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -316
1H-tetrazol-2-yl
CH2OCH2CF3




text missing or illegible when filed -317
1H-tetrazol-2-yl
CH2SCH3




text missing or illegible when filed -318
1H-tetrazol-2-yl
CH2SCH2CH3







text missing or illegible when filed -319
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -320
1H-tetrazol-2-yl
CH2SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 86








physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -321
1H-tetrazol-2-yl
CH2SOCH3




text missing or illegible when filed -322
1H-tetrazol-2-yl
CH2SOCH2CH3







text missing or illegible when filed -323
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -324
1H-tetrazol-2-yl
CH2SOCH2CF3




text missing or illegible when filed -325
1H-tetrazol-2-yl
CH2SO2CH3




text missing or illegible when filed -326
1H-tetrazol-2-yl
CH2SO2CH2CH3







text missing or illegible when filed -327
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -328
1H-tetrazol-2-yl
CH2SO2CH2CF3




text missing or illegible when filed -329
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3




text missing or illegible when filed -330
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed -331
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed -332
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed -333
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3




text missing or illegible when filed -334
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed -335
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




text missing or illegible when filed -336
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed -337
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3







text missing or illegible when filed -338
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -339
1H-tetrazol-2-yl


embedded image









text missing or illegible when filed -340
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3







text missing or illegible when filed -341
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SO2CHtext missing or illegible when filed )






text missing or illegible when filed indicates data missing or illegible when filed













TABLE 87









embedded image


















physical





property


compound


(melting


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
point-ND)





7-1
Cl
CH3



7-2
Cl
CF3



7-3
Cl
CH2CH3



7-4
Cl
CH2OCH2CH3






7-5
Cl


embedded image








7-6
Cl
CH2OCH2CF3



7-7
Cl
CH2SCH3



7-8
Cl
CH2SCH2CH3






7-9
Cl


embedded image








7-10
Cl
CH2SCH2CF3



7-11
Cl
CH2SOCH3



7-12
Cl
CH2SOCH2CH3






7-13
Cl


embedded image








7-14
Cl
CH2SOCH2CF3



7-15
Cl
CH2SO2CH3



7-16
Cl
CH2SO2CH2CH3






7-17
Cl


embedded image








7-18
Cl
CH2SO2CH2CF3



7-19
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



7-20
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



7-21
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



7-22
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



7-23
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



7-24
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CH3



7-25
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



7-26
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



7-27
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






7-28
Cl


embedded image








7-29
Cl


embedded image








7-30
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



7-31
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SO2CHtext missing or illegible when filed )



7-32
SCHtext missing or illegible when filed
CH3



7-33
SCHtext missing or illegible when filed
CF3



7-34
SCHtext missing or illegible when filed
CH2OCH3



7-35
SCHtext missing or illegible when filed
CH2OCH2CH3






7-36
SCHtext missing or illegible when filed


embedded image








7-37
SCHtext missing or illegible when filed
CH2OCH2CF3



7-38
SCHtext missing or illegible when filed
CH2SCH3



7-39
SCHtext missing or illegible when filed
CH2SCH2CH3






7-40
SCHtext missing or illegible when filed


embedded image








text missing or illegible when filed indicates data missing or illegible when filed

















TABLE 88









physical






property



compound


(melting point-



number
R4
R1
ND)








7-41
SCH3
CH2SCH2CF3




7-42
SCH3
CH2SOCH3




7-43
SCH3
CH2SOCH2CH3







7-44
SCH3


embedded image









7-45
SCH3
CH2SOCH2CF3




7-46
SCH3
CH2SO2CH3




7-47
SCH3
CH2SO2CH2CH3







7-48
SCH3


embedded image









7-49
SCH3
CH2SO2CH2CF3




7-50
SCH3
CH2O(CH2)2OCH3




7-51
SCH3
CH2O(CH2)2OCH2CH3




7-52
SCH3
CH2O(CH2)2OCH2CF3




7-53
SCH3
CH2O(CH2)2SCH3




7-54
SCH3
CH2O(CH2)2SCH2CF3




7-55
SCH3
CH2O(CH2)2SOCH3




7-56
SCH3
CH2O(CH2)2SOCH2CF3




7-57
SCH3
CH2O(CH2)2SO2CH3




7-58
SCH3
CH2O(CH2)2SO2CH2CF3







7-59
SCH3


embedded image









7-60
SCH3


embedded image









7-61
SCH3
CH2O(CH2)2NHSO2CH3




7-62
SCH3
CH2O(CH3)2N(CH3)(SO2CH3)




7-63
SCH2CH3
CH3




7-64
SCH2CH3
CF3




7-65
SCH2CH3
CH2OCH3




7-66
SCH2CH3
CH2OCH2CH3







7-67
SCH2CH3


embedded image









7-68
SCH2CH3
CH2OCH2CF3




7-69
SCH2CH3
CH2SCH3




7-70
SCH2CH3
CH2SCH2CH3







7-71
SCH2CH3


embedded image









7-72
SCH2CH3
CH2SCH2CF3




7-73
SCH2CH3
CH2SOCH3




7-74
SCH2CH3
CH2SOCH2CH3







7-75
SCH2CH3


embedded image









7-76
SCH2CH3
CH2SOCH2CF3




7-77
SCH2CH3
CH2SO2CH3




7-78
SCH2CH3
CH2SO2CH2CH3







7-79
SCH2CH3


embedded image









7-80
SCH2CH3
CH2SO2CH2CF3



















TABLE 89








physical





property





(melting


compound


point-


number
R4
R1
ND)







7-81 
SCH2CH3
CH2O(CH2)2OCH3



7-82 
SCH2CH3
CH2O(CH2)2OCH2CH3



7-83 
SCH2CH3
CH2O(CH2)2OCH2CF3



7-84 
SCH2CH3
CH2O(CH2)2SCH3



7-85 
SCH2CH3
CH2O(CH2)2SCH2CF3



7-86 
SCH2CH3
CH2O(CH2)2SOCH3



7-87 
SCH2CH3
CH2O(CH2)2SOCH2CF3



7-88 
SCH2CH3
CH2O(CH2)2SO2CH3



7-89 
SCH2CH3
CH2O(CH2)2SO2CH2CF3






7-90 
SCH2CH3


embedded image








7-91 
SCH2CH3


embedded image








7-92 
SCH2CH3
CH2O(CH2)2NHSO2CH3



7-93 
SCH2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



7-94 
S(CH2)2CH3
CH3



7-95 
S(CH2)2CH3
CF3



7-96 
S(CH2)2CH3
CH2OCH3



7-97 
S(CH2)2CH3
CH2OCH2CH3






7-98 
S(CH2)2CH3


embedded image








7-99 
S(CH2)2CH3
CH2OCH2CF3



7-100
S(CH2)2CH3
CH2SCH3



7-101
S(CH2)2CH3
CH2SCH2CH3






7-102
S(CH2)2CH3


embedded image








7-103
S(CH2)2CH3
CH2SCH2CF3



7-104
S(CH2)2CH3
CH2SOCH3



7-105
S(CH2)2CH3
CH2SOCH2CH3






7-106
S(CH2)2CH3


embedded image








7-107
S(CH2)2CH3
CH2SOCH2CF3



7-108
S(CH2)2CH3
CH2SO2CH3



7-109
S(CH2)2CH3
CH2SO2CH2CH3






7-110
S(CH2)2CH3


embedded image








7-111
S(CH2)2CH3
CH2SO2CH2CF3



7-112
S(CH2)2CH3
CH2O(CH2)2OCH3



7-113
S(CH2)2CH3
CH2O(CH2)2OCH2CH3



7-114
S(CH2)2CH3
CH2O(CH2)2OCH2CF3



7-115
S(CH2)2CH3
CH2O(CH2)2SCH3



7-116
S(CH2)2CH3
CH2O(CH2)2SCH2CF3



7-117
S(CH2)2CH3
CH2O(CH2)2SOCH3



7-118
S(CH2)2CH3
CH2O(CH2)2SOCH2CF3



7-119
S(CH2)2CH3
CH2O(CH2)2SO2CH3



7-120
S(CH2)2CH3
CH2O(CH2)2SO2CH2CF3



















TABLE 90








physical





property


compound


(melting point-


number
Rtext missing or illegible when filed
R1
ND)







7-text missing or illegible when filed

text missing or illegible when filed



embedded image








7-text missing or illegible when filed

text missing or illegible when filed



embedded image








7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed







7-text missing or illegible when filed

text missing or illegible when filed



embedded image








7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed







7-text missing or illegible when filed

text missing or illegible when filed



embedded image








7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed







7-text missing or illegible when filed

text missing or illegible when filed



embedded image











7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed







7-text missing or illegible when filed

text missing or illegible when filed



embedded image








7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed







7-text missing or illegible when filed

text missing or illegible when filed



embedded image








7-text missing or illegible when filed

text missing or illegible when filed



embedded image








7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed




7-text missing or illegible when filed

text missing or illegible when filed


text missing or illegible when filed







7-text missing or illegible when filed

text missing or illegible when filed



embedded image








text missing or illegible when filed indicates data missing or illegible when filed

















TABLE 91









physical






property



compound


(melting point-



number
R4
R1
ND)








7-161
SCH2C6H5
CH2OCH2CF3




7-162
SCH2C6H5
CH2SCH3




7-163
SCH2C6H5
CH2SCH2CH3







7-164
SCH2C6H5


embedded image









7-165
SCH2C6H5
CH2SCH2CF3




7-166
SCH2C6H5
CH2SOCH3




7-167
SCH2C6H5
CH2SOCH2CH3







7-168
SCH2C6H5


embedded image









7-169
SCH2C6H5
CH2SOCH2CF3




7-170
SCH2C6H5
CH2SO2CH3




7-171
SCH2C6H5
CH2SO2CH2CH3







7-172
SCH2C6H5


embedded image









7-173
SCH2C6H5
CH2SO2CH2CF3




7-174
SCH2C6H5
CH2O(CH2)2OCH3




7-175
SCH2C6H5
CH2O(CH2)2OCH2CH3




7-176
SCH2C6H5
CH2O(CH2)2OCH2CF3




7-177
SCH2C6H5
CH2O(CH2)2SCH3




7-178
SCH2C6H5
CH2O(CH2)2SCH2CF3




7-179
SCH2C6H5
CH2O(CH2)2SOCH3




7-180
SCH2C6H5
CH2O(CH2)2SOCH2CF3




7-181
SCH2C6H5
CH2O(CH2)2SO2CH3




7-182
SCH2C6H5
CH2O(CH2)2SO2CH2CF3







7-183
SCH2C6H5


embedded image









7-184
SCH2C6H5


embedded image









7-185
SCH2C6H5
CH2O(CH2)2NHSO2CH3




7-186
SCH2C6H5
CH2O(CH2)2N(CH3)(SO2CH3)




7-187
1H-text missing or illegible when filed -1-yl
CH3




7-188
1H-text missing or illegible when filed -1-yl
CF3




7-189
1H-text missing or illegible when filed -1-yl
CH2OCH3




7-190
1H-text missing or illegible when filed -1-yl
CH2OCH2CH3







7-191
1H-text missing or illegible when filed -1-yl


embedded image









7-192
1H-text missing or illegible when filed -1-yl
CH2OCH2CF3




7-193
1H-text missing or illegible when filed -1-yl
CH2SCH3




7-194
1H-text missing or illegible when filed -1-yl
CH2SCH2CH3







7-195
1H-text missing or illegible when filed -1-yl


embedded image









7-196
1H-text missing or illegible when filed -1-yl
CH2SCH2CF3




7-197
1H-text missing or illegible when filed -1-yl
CH2SOCH3




7-198
1H-text missing or illegible when filed -1-yl
CH2SOCH2CH3







7-199
1H-text missing or illegible when filed -1-yl


embedded image









7-200
1H-text missing or illegible when filed -1-yl
CH2SOCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 92





compound


physical property


number
R4
R1
(melting point-ND)







7-201
1H-pyrazole-1-yl
CH2SO2CH3



7-202
1H-pyrazole-1-yl
CH2SO2CH2CH3






7-203
1H-pyrazole-1-yl


embedded image








7-204
1H-pyrazole-1-yl
CH2SO2CH2CF3



7-205
1H-pyrazole-1-yl
CH2O(CH2)2OCH3



7-206
1H-pyrazole-1-yl
CH2O(CH2)2OCH2CH3



7-207
1H-pyrazole-1-yl
CH2O(CH2)2OCH2CF3



7-208
1H-pyrazole-1-yl
CH2O(CH2)2SCH3



7-209
1H-pyrazole-1-yl
CH2O(CH2)2SCH2CF3



7-210
1H-pyrazole-1-yl
CH2O(CH2)2SOCH3



7-211
1H-pyrazole-1-yl
CH2O(CH2)2SOCH2CF3



7-212
1H-pyrazole-1-yl
CH2O(CH2)2SO2CH3



7-213
1H-pyrazole-1-yl
CH2O(CH2)2SO2CH2CF3






7-214
1H-pyrazole-1-yl


embedded image








7-215
1H-pyrazole-1-yl


embedded image








7-216
1H-pyrazole-1-yl
CH2O(CH2)2NHSO2CH3



7-217
1H-pyrazole-1-yl
CH2O(CH2)2N(CH3)(SO2CH3)



7-218
1H-imidazole-1-yl
CH3



7-219
1H-imidazole-1-yl
CF3



7-220
1H-imidazole-1-yl
CH2OCH3



7-221
1H-imidazole-1-yl
CH2OCH2CH3






7-222
1H-imidazole-1-yl


embedded image








7-223
1H-imidazole-1-yl
CH2OCH2CF3



7-224
1H-imidazole-1-yl
CH2SCH3



7-225
1H-imidazole-1-yl
CH2SCH2CH3






7-226
1H-imidazole-1-yl


embedded image








7-227
1H-imidazole-1-yl
CH2SCH2CF3



7-228
1H-imidazole-1-yl
CH2SOCH3



7-229
1H-imidazole-1-yl
CH2SOCH2CH3






7-230
1H-imidazole-1-yl


embedded image








7-231
1H-imidazole-1-yl
CH2SOCH2CF3



7-232
1H-imidazole-1-yl
CH2SO2CH3



7-233
1H-imidazole-1-yl
CH2SO2CH2CH3






7-234
1H-imidazole-1-yl


embedded image








7-235
1H-imidazole-1-yl
CH2SO2CH2CF3



7-236
1H-imidazole-1-yl
CH2O(CH2)2OCH3



7-237
1H-imidazole-1-yl
CH2O(CH2)2OCH2CH3



7-238
1H-imidazole-1-yl
CH2O(CH2)2OCH2CF3



7-239
1H-imidazole-1-yl
CH2O(CH2)2SCH3



7-240
1H-imidazole-1-yl
CH2O(CH2)2SCH2CF3




















TABLE 93









physical






property



compound


(melting point-



number
R4
R1
ND)








7-241

text missing or illegible when filed

CH2O(CH2)2SOCH3




7-242

text missing or illegible when filed

CH2O(CH2)2SOCH2CF3




7-243

text missing or illegible when filed

CH2O(CH2)2SO2CH3




7-244

text missing or illegible when filed

CH2O(CH2)2SO2CH2CF3







7-245

text missing or illegible when filed



embedded image









7-246

text missing or illegible when filed



embedded image









7-247

text missing or illegible when filed

CH2O(CH2)2NHSO2CH3




7-248

text missing or illegible when filed

CH2O(CH2)2N(CH3)(SO2CH3)




7-249

text missing or illegible when filed

CH3




7-250

text missing or illegible when filed

CF3




7-251

text missing or illegible when filed

CH2OCH3




7-252

text missing or illegible when filed

CH2OCH2CH3







7-253

text missing or illegible when filed



embedded image









7-254

text missing or illegible when filed

CH2OCH2CF3




7-255

text missing or illegible when filed

CH2SCH3




7-256

text missing or illegible when filed

CH2SCH2CH3







7-257

text missing or illegible when filed



embedded image









7-258

text missing or illegible when filed

CH2SCH2CF3




7-259

text missing or illegible when filed

CH2SOCH3




7-260

text missing or illegible when filed

CH2SOCH2CH3







7-261

text missing or illegible when filed



embedded image









7-262

text missing or illegible when filed

CH2SOCH2CF3




7-263

text missing or illegible when filed

CH2SO2CH3




7-264

text missing or illegible when filed

CH2SO2CH2CH3







7-265

text missing or illegible when filed



embedded image









7-266

text missing or illegible when filed

CH2SO2CH2CF3




7-267

text missing or illegible when filed

CH2O(CH2)2OCH3




7-268

text missing or illegible when filed

CH2O(CH2)2OCH2CH3




7-269

text missing or illegible when filed

CH2O(CH2)2OCH2CF3




7-270

text missing or illegible when filed

CH2O(CH2)2SCH3




7-271

text missing or illegible when filed

CH2O(CH2)2SCH2CF3




7-272

text missing or illegible when filed

CH2O(CH2)2SOCH3




7-273

text missing or illegible when filed

CH2O(CH2)2SOCH2CF3




7-274

text missing or illegible when filed

CH2O(CH2)2SO2CH3




7-275

text missing or illegible when filed

CH2O(CH2)2SO2CH2CF3







7-276

text missing or illegible when filed



embedded image









7-277

text missing or illegible when filed



embedded image









7-278

text missing or illegible when filed

CH2O(CH2)2NHSO2CH3




7-279

text missing or illegible when filed

CH2O(CH2)2N(CH3)(SO2CH3)




7-280

text missing or illegible when filed

CH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 94








physical





property


com-


(melting


pound


point-


number
R4
R1
ND)







7-281
1H-text missing or illegible when filed -1-yl
CF3



7-282
1H-text missing or illegible when filed -1-yl
CH2OCH3



7-283
1H-text missing or illegible when filed -1-yl
CH2OCH2CH3






7-284
1H-text missing or illegible when filed -1-yl


embedded image








7-285
1H-text missing or illegible when filed -1-yl
CH2OCH2CF3



7-286
1H-text missing or illegible when filed -1-yl
CH2SCH3



7-287
1H-text missing or illegible when filed -1-yl
CH2SCH2CH3






7-288
1H-text missing or illegible when filed -1-yl


embedded image








7-289
1H-text missing or illegible when filed -1-yl
CH2SCH2CF3



7-290
1H-text missing or illegible when filed -1-yl
CH2SOCH3



7-291
1H-text missing or illegible when filed -1-yl
CH2SOCH2CH3






7-292
1H-text missing or illegible when filed -1-yl


embedded image








7-293
1H-text missing or illegible when filed -1-yl
CH2SOCH2CF3



7-294
1H-text missing or illegible when filed -1-yl
CH2SO2CH3



7-295
1H-text missing or illegible when filed -1-yl
CH2SO2CH2CH3






7-296
1H-text missing or illegible when filed -1-yl


embedded image








7-297
1H-text missing or illegible when filed -1-yl
CH2SO2CH2CF3



7-298
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH3



7-299
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH2CH3



7-300
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH2CF3



7-301
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SCH3



7-302
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SCH2CF3



7-303
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SOCH3



7-304
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SOCH2CF3



7-305
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SO2CH3



7-306
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SO2CH2CF3






7-307
1H-text missing or illegible when filed -1-yl


embedded image








7-308
1H-text missing or illegible when filed -1-yl


embedded image








7-309
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2NHSO2CH3



7-310
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2N(CH3)(SO2CH3)



7-311
1H-text missing or illegible when filed -2-yl
CH3



7-312
1H-text missing or illegible when filed -2-yl
CF3



7-313
1H-text missing or illegible when filed -2-yl
CH2OCH3



7-314
1H-text missing or illegible when filed -2-yl
CH2OCH2CH3






7-315
1H-text missing or illegible when filed -2-yl


embedded image








7-316
1H-text missing or illegible when filed -2-yl
CH2OCH2CF3



7-317
1H-text missing or illegible when filed -2-yl
CH2SCH3



7-318
1H-text missing or illegible when filed -2-yl
CH2SCH2CH3






7-319
1H-text missing or illegible when filed -2-yl


embedded image








7-320
1H-text missing or illegible when filed -2-yl
CH2SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 95








physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
R1
ND)







7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CHtext missing or illegible when filed






7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl


embedded image








7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed






7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl


embedded image








7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed






7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl


embedded image








7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl


embedded image








7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHtext missing or illegible when filed



7-text missing or illegible when filed
1H-text missing or illegible when filed -2-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SOtext missing or illegible when filed CHtext missing or illegible when filed )






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 96








physical





property


compound


(melting point-


number
R4
R1
ND)







8-1 
Cl
CH3



8-2 
Cl
CF3



8-3 
Cl
CH2OCH3



8-4 
Cl
CH2OCH2CH3






8-5 
Cl


embedded image








8-6 
Cl
CH2OCH2CF3



8-7 
Cl
CH2SCH3



8-8 
Cl
CH2SCH2CH3






8-9 
Cl


embedded image








8-10
Cl
CH2SCH2CF3



8-11
Cl
CH2SOCH3



8-12
Cl
CH2SOCH2CH3






8-13
Cl


embedded image








8-14
Cl
CH2SOCH2CF3



8-15
Cl
CH2SO2CH3



8-16
Cl
CH2SO2CH2CH3






8-17
Cl


embedded image








8-18
Cl
CH2SO2CH2CF3



8-19
Cl
CH2O(CH2)2OCH3



8-20
Cl
CH2O(CH2)2OCH2CH3



8-21
Cl
CH2O(CH2)2OCH2CF3



8-22
Cl
CH2O(CH2)2SCH3



8-23
Cl
CH2O(CH2)2SCH2CF3



8-24
Cl
CH2O(CH2)2SOCH3



8-25
Cl
CH2O(CH2)2SOCH2CF3



8-26
Cl
CH2O(CH2)2SO2CH3



8-27
Cl
CH2O(CH2)2SO2CH2CF3






8-28
Cl


embedded image








8-29
Cl


embedded image








8-30
Cl
CH2O(CH2)2NHSO2CH3



8-31
Cl
CH2O(CH2)2N(CH3)(SO2CH3)



8-32
SCH3
CH3



8-33
SCH3
CF3



8-34
SCH3
CH2OCH3



8-35
SCH3
CH2OCH2CH3






8-36
SCH3


embedded image








8-37
SCH3
CH2OCH2CF3



8-38
SCH3
CH2SCH3



8-39
SCH3
CH2SCH2CH3






8-40
SCH3


embedded image





















TABLE 97








physical





property


compound


(melting


number
R4
R1
point-ND)







8-41
SCH3
CH2SCH2CF3



8-42
SCH3
CH2SOCH3



8-43
SCH3
CH2SOCH2CH3






8-44
SCH3


embedded image








8-45
SCH3
CH2SOCH2CF3



8-46
SCH3
CH2SO2CH3



8-47
SCH3
CH2SO2CH2CH3






8-48
SCH3


embedded image








8-49
SCH3
CH2SO2CH2CF3



8-50
SCH3
CH2O(CH2)2OCH3



8-51
SCH3
CH2O(CH2)2OCH2CH3



8-52
SCH3
CH2O(CH2)2OCH2CF3



8-53
SCH3
CH2O(CH2)2SCH3



8-54
SCH3
CH2O(CH2)2SCH2CF3



8-55
SCH3
CH2O(CH2)2SOCH3



8-56
SCH3
CH2O(CH2)2SOCH2CF3



8-57
SCH3
CH2O(CH2)2SO2CH3



8-58
SCH3
CH2O(CH2)2SO2CH2CF3






8-59
SCH3


embedded image








8-60
SCH3


embedded image








8-61
SCH3
CH2O(CH2)2NHSO2CH3



8-62
SCH3
CH2O(CH2)2N(CH3)(SO2CH3)



8-63
SCH2CH3
CH3



8-64
SCH2CH3
CF3



8-65
SCH2CH3
CH2OCH3



8-66
SCH2CH3
CH2OCH2CH3






8-67
SCH2CH3


embedded image








8-68
SCH2CH3
CH2OCH2CF3



8-69
SCH2CH3
CH2SCH3



8-70
SCH2CH3
CH2SCH2CH3






8-71
SCH2CH3


embedded image








8-72
SCH2CH3
CH2SCH2CF3



8-73
SCH2CH3
CH2SOCH3



8-74
SCH2CH3
CH2SOCH2CH3






8-75
SCH2CH3


embedded image








8-76
SCH2CH3
CH2SOCH2CF3



8-77
SCH2CH3
CH2SO2CH3



8-78
SCH2CH3
CH2SO2CH2CH3






8-79
SCH2CH3


embedded image








8-80
SCH2CH3
CH2SO2CH2CF3



















TABLE 98








physical





property


compound


(melting


number
R4
R1
point-ND)







8-81 
SCH2CH3
CH2O(CH2)2OCH3



8-82 
SCH2CH3
CH2O(CH2)2OCH2CH3



8-83 
SCH2CH3
CH2O(CH2)2OCH2CF3



8-84 
SCH2CH3
CH2O(CH2)2SCH3



8-85 
SCH2CH3
CH2O(CH2)2SCH2CF3



8-86 
SCH2CH3
CH2O(CH2)2SOCH3



8-87 
SCH2CH3
CH2O(CH2)2SOCH2CF3



8-88 
SCH2CH3
CH2O(CH2)2SO2CH3



8-89 
SCH2CH3
CH2O(CH2)2SO2CH2CF3






8-90 
SCH2CH3


embedded image








8-91 
SCH2CH3


embedded image








8-92 
SCH2CH3
CH2O(CH2)2NHSO2CH3



8-93 
SCH2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



8-94 
S(CH2)2CH3
CH3



8-95 
S(CH2)2CH3
CF3



8-96 
S(CH2)2CH3
CH2OCH3



8-97 
S(CH2)2CH3
CH2OCH2CH3






8-98 
S(CH2)2CH3


embedded image








8-99 
S(CH2)2CH3
CH2OCH2CF3



8-100
S(CH2)2CH3
CH2SCH3



8-101
S(CH2)2CH3
CH2SCH2CH3






8-102
S(CH2)2CH3


embedded image








8-103
S(CH2)2CH3
CH2SCH2CF3



8-104
S(CH2)2CH3
CH2SOCH3



8-105
S(CH2)2CH3
CH2SOCH2CH3






8-106
S(CH2)2CH3


embedded image








8-107
S(CH2)2CH3
CH2SOCH2CF3



8-108
S(CH2)2CH3
CH2SO2CH3



8-109
S(CH2)2CH3
CH2SO2CH2CH3






8-110
S(CH2)2CH3


embedded image








8-111
S(CH2)2CH3
CH2SO2CH2CF3



8-112
S(CH2)2CH3
CH2O(CH2)2OCH3



8-113
S(CH2)2CH3
CH2O(CH2)2OCH2CH3



8-114
S(CH2)2CH3
CH2O(CH2)2OCH2CF3



8-115
S(CH2)2CH3
CH2O(CH2)2SCH3



8-116
S(CH2)2CH3
CH2O(CH2)2SCH2CF3



8-117
S(CH2)2CH3
CH2O(CH2)2SOCH3



8-118
S(CH2)2CH3
CH2O(CH2)2SOCH2CF3



8-119
S(CH2)2CH3
CH2O(CH2)2SO2CH3



8-120
S(CH2)2CH3
CH2O(CH2)2SO2CH2CF3



















TABLE 99








physical





property


compound


(melting


number
R4
R1
point-ND)







8-121
S(CH2)2CH3


embedded image








8-122
S(CH2)2CH3


embedded image








8-123
S(CH2)2CH3
CH2O(CH2)2NHSO2CH3



8-124
S(CH2)2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



8-125
SC6H5
CH3



8-126
SC6H5
CF3



8-127
SC6H5
CH2OCH3



8-128
SC6H5
CH2OCH2CH3






8-129
SC6H5


embedded image








8-130
SC6H5
CH2OCH2CF3



8-131
SC6H5
CH2SCH3



8-132
SC6H5
CH2SCH2CH3






8-133
SC6H5


embedded image








8-134
SC6H5
CH2SCH2CF3



8-135
SC6H5
CH2SOCH3



8-136
SC6H5
CH2SOCH2CH3






8-137
SC6H5


embedded image








8-138
SC6H5
CH2SOCH2CF3



8-139
SC6H5
CH2SO2CH3



8-140
SC6H5
CH2SO2CH2CH3






8-141
SC6H5


embedded image








8-142
SC6H5
CH2SO2CH2CF3



8-143
SC6H5
CH2O(CH2)2OCH3



8-144
SC6H5
CH2O(CH2)2OCH2CH3



8-145
SC6H5
CH2O(CH2)2OCH2CF3



8-146
SC6H5
CH2O(CH2)2SCH3



8-147
SC6H5
CH2O(CH2)2SCH2CF3



8-148
SC6H5
CH2O(CH2)2SOCH3



8-149
SC6H5
CH2O(CH2)2SOCH2CF3



8-150
SC6H5
CH2O(CH2)2SO2CH3



8-151
SC6H5
CH2O(CH2)2SO2CH2CF3






8-152
SC6H5


embedded image








8-153
SC6H5


embedded image








8-154
SC6H5
CH2O(CH2)2NHSO2CH3



8-155
SC6H5
CH2O(CH2)2N(CH3)(SO2CH3)



8-156
SCH2C6H5
CH3



8-157
SCH2C6H5
CF3



8-158
SCH2C6H5
CH2OCH3



8-159
SCH2C6H5
CH2OCH2CH3



8-160
SCH2C6H5


embedded image





















TABLE 100








physical





property


compound



text missing or illegible when filed



number
R4
R1

text missing or illegible when filed








8-161
SCH2C6H5
CH2OCH2CF3



8-162
SCH2C6H5
CH2SCH3



8-163
SCH2C6H5
CH2SCH2CH3






8-164
SCH2C6H5


embedded image








8-165
SCH2C6H5
CH2SCH2CF3



8-166
SCH2C6H5
CH2SOCH3



8-167
SCH2C6H5
CH2SOCH2CH3






8-168
SCH2C6H5


embedded image








8-169
SCH2C6H5
CH2SOCH2CF3



8-170
SCH2C6H5
CH2SO2CH3



8-171
SCH2C6H5
CH2SO2CH2CH3






8-172
SCH2C6H5


embedded image








8-173
SCH2C6H5
CH2SO2CH2CF3



8-174
SCH2C6H5
CH2O(CH2)2OCH3



8-175
SCH2C6H5
CH2O(CH2)2OCH2CH3



8-176
SCH2C6H5
CH2O(CH2)2OCH2CF3



8-177
SCH2C6H5
CH2O(CH2)2SCH3



8-178
SCH2C6H5
CH2O(CH2)2SCH2CF3



8-179
SCH2C6H5
CH2O(CH2)2SOCH3



8-180
SCH2C6H5
CH2O(CH2)2SOCH2CF3



8-181
SCH2C6H5
CH2O(CH2)2SO2CH2



8-182
SCH2C6H5
CH2O(CH2)2SO2CH2CF3






8-183
SCH2C6H5


embedded image








8-184
SCH2C6H5


embedded image








8-185
SCH2C6H5
CH2O(CH2)2NHSO2CH3



8-186
SCH2C6H5
CH2O(CH2)2N(CH3)(SO2CH3)



8-187

text missing or illegible when filed

CH3



8-188

text missing or illegible when filed

CF3



8-189

text missing or illegible when filed

CH2OCH3



8-190

text missing or illegible when filed

CH2OCH2CH3






8-191

text missing or illegible when filed



embedded image








8-192

text missing or illegible when filed

CH2OCH2CF3



8-193

text missing or illegible when filed

CH2SCH3



8-194

text missing or illegible when filed

CH2SCH2CH3






8-195

text missing or illegible when filed



embedded image








8-196

text missing or illegible when filed

CH2SCH2CF3



8-197

text missing or illegible when filed

CH2SOCH3



8-198

text missing or illegible when filed

CH2SOCH2CH3






8-199

text missing or illegible when filed



embedded image








8-200

text missing or illegible when filed

CH2SOCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 101








physical





property


compound


(melting point-


number
R4
R1
ND)







8-201
1H-pyrazole-
CH2SO2CH3




1-yl




8-202
1H-pyrazole-
CH2SO2CH2CH3




1-yl







8-203
1H-pyrazole- 1-yl


embedded image








8-204
1H-pyrazole-
CH2SO2CH2CF3




1-yl




8-205
1H-pyrazole-
CH2O(CH2)2OCH3




1-yl




8-206
1H-pyrazole-
CH2O(CH2)2OCH2CH3




1-yl




8-207
1H-pyrazole-
CH2O(CH2)2OCH2CF3




1-yl




8-208
1H-pyrazole-
CH2O(CH2)2SCH3




1-yl




8-209
1H-pyrazole-
CH2O(CH2)2SCH2CF3




1-yl




8-210
1H-pyrazole-
CH2O(CH2)2SOCH3




1-yl




8-211
1H-pyrazole-
CH2O(CH2)2SOCH2CF3




1-yl




8-212
1H-pyrazole-
CH2O(CH2)2SO2CH3




1-yl




8-213
1H-pyrazole-
CH2O(CH2)2SO2CH2CF3




1-yl







8-214
1H-pyrazole- 1-yl


embedded image








8-215
1H-pyrazole- 1-yl


embedded image








8-216
1H-pyrazole-
CH2O(CH2)2NHSO2CH3




1-yl




8-217
1H-pyrazole-
CH2O(CH2)2N(CH3)(SO2CH3)




1-yl




8-218
1H-imidazole-
CH3




1-yl




8-219
1H-imidazole-
CF3




1-yl




8-220
1H-imidazole-
CH2OCH3




1-yl




8-221
1H-imidazole-
CH2OCH2CH3




1-yl







8-222
1H-imidazole- 1-yl


embedded image








8-223
1H-imidazole-
CH2OCH2CF3




1-yl




8-224
1H-imidazole-
CH2SCH3




1-yl




8-225
1H-imidazole-
CH2SCH2CH3




1-yl







8-226
1H-imidazole- 1-yl


embedded image








8-227
1H-imidazole-
CH2SCH2CF3




1-yl




8-228
1H-imidazole-
CH2SOCH3




1-yl




8-229
1H-imidazole-
CH2SOCH2CH3




1-yl







8-230
1H-imidazole- 1-yl


embedded image








8-231
1H-imidazole-
CH2SOCH2CF3




1-yl




8-232
1H-imidazole-
CH2SO2CH3




1-yl




8-233
1H-imidazole-
CH2SO2CH2CH3




1-yl







8-234
1H-imidazole- 1-yl


embedded image








8-235
1H-imidazole-
CH2SO2CH2CF3




1-yl




8-236
1H-imidazole-
CH2O(CH2)2OCH3




1-yl




8-237
1H-imidazole-
CH2O(CH2)2OCH2CH3




1-yl




8-238
1H-imidazole-
CH2O(CH2)2OCH2CF3




1-yl




8-239
1H-imidazole-
CH2O(CH2)2SCH3




1-yl




8-240
1H-imidazole-
CH2O(CH2)2SCH2CF3




1-yl



















TABLE 102








physical





property


compound


(melting


number
R4
R1
point-ND)







8-241
1H- text missing or illegible when filed
CH2O(CH2)2SOCH3



8-242
1H- text missing or illegible when filed
CH2O(CH2)2SOCH2CF3



8-243
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH3



8-244
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH2CF3






8-245
1H- text missing or illegible when filed


embedded image








8-246
1H- text missing or illegible when filed


embedded image








8-247
1H- text missing or illegible when filed
CH2O(CH2)2NHSO2CH3



8-248
1H- text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO2CH3)



8-249
1H- text missing or illegible when filed
CH3



8-250
1H- text missing or illegible when filed
CF3



8-251
1H- text missing or illegible when filed
CH2OCH3



8-252
1H- text missing or illegible when filed
CH2OCH2CH3






8-253
1H- text missing or illegible when filed


embedded image








8-254
1H- text missing or illegible when filed
CH2OCH2CF3



8-255
1H- text missing or illegible when filed
CH2SCH3



8-256
1H- text missing or illegible when filed
CH2SCH2CH3






8-257
1H- text missing or illegible when filed


embedded image








8-258
1H- text missing or illegible when filed
CH2SCH2CF3



8-259
1H- text missing or illegible when filed
CH2SOCH3



8-260
1H- text missing or illegible when filed
CH2SOCH2CH3






8-261
1H- text missing or illegible when filed


embedded image








8-262
1H- text missing or illegible when filed
CH2SOCH2CF3



8-263
1H- text missing or illegible when filed
CH2SO2CH3



8-264
1H- text missing or illegible when filed
CH2SO2CH2CH3






8-265
1H- text missing or illegible when filed


embedded image








8-266
1H- text missing or illegible when filed
CH2SO2CH2CF3



8-267
1H- text missing or illegible when filed
CH2O(CH2)2OCH3



8-268
1H- text missing or illegible when filed
CH2O(CH2)2OCH2CH3



8-269
1H- text missing or illegible when filed
CH2O(CH2)2OCH2CF3



8-270
1H- text missing or illegible when filed
CH2O(CH2)2SCH3



8-271
1H- text missing or illegible when filed
CH2O(CH2)2SCH2CF3



8-272
1H- text missing or illegible when filed
CH2O(CH2)2SOCH3



8-273
1H- text missing or illegible when filed
CH2O(CH2)2SOCH2CF3



8-274
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH3



8-275
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH2CF3






8-276
1H- text missing or illegible when filed


embedded image








8-277
1H- text missing or illegible when filed


embedded image








8-278
1H- text missing or illegible when filed
CH2O(CH2)2NHSO2CH3



8-279
1H- text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO2CH3)



8-280
1H- text missing or illegible when filed
CH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 103








physical





property





(melting


compound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed -281
1H-tetrazole-1-yl
CF3




text missing or illegible when filed -282
1H-tetrazole-1-yl
CH2OCH3




text missing or illegible when filed -283
1H-tetrazole-1-yl
CH2OCH2CH3







text missing or illegible when filed -284
1H-tetrazole-1-yl


embedded image






text missing or illegible when filed -285
1H-tetrazole-1-yl
CH2OCH2CFH3




text missing or illegible when filed -286
1H-tetrazole-1-yl
CH2SCH3




text missing or illegible when filed -287
1H-tetrazole-1-yl
CH2OCH3H2SCH2CH3







text missing or illegible when filed -288
1H-tetrazole-1-yl


embedded image









text missing or illegible when filed -289
1H-tetrazole-1-yl
CH2SCH2CF3




text missing or illegible when filed -290
1H-tetrazole-1-yl
CH2SOCH3




text missing or illegible when filed -291
1H-tetrazole-1-yl
CH2SOCH2CH3







text missing or illegible when filed -292
1H-tetrazole-1-yl


embedded image









text missing or illegible when filed -293
1H-tetrazole-1-yl
CH2SOCH2CF3




text missing or illegible when filed -294
1H-tetrazole-1-yl
CH2SO2CH3




text missing or illegible when filed -295
1H-tetrazole-1-yl
CH2SO2CH2CH3







text missing or illegible when filed -296
1H-tetrazole-1-yl


embedded image









text missing or illegible when filed -297
1H-tetrazole-1-yl
CH2SO2CH2CF3




text missing or illegible when filed -298
1H-tetrazole-1-yl
CH2O(CH2)2OCH3




text missing or illegible when filed -299
1H-tetrazole-1-yl
CH2O(CH2)2OCH2CH3




text missing or illegible when filed -300
1H-tetrazole-1-yl
CH2O(CH2)2OCH2CF3




text missing or illegible when filed -301
1H-tetrazole-1-yl
CH2O(CH2)2SCH3




text missing or illegible when filed -302
1H-tetrazole-1-yl
CH2O(CH2)2SCH2CF3




text missing or illegible when filed -303
1H-tetrazole-1-yl
CH2O(CH2)2SOCH3




text missing or illegible when filed -304
1H-tetrazole-1-yl
CH2O(CH2)2SOCH2CF3




text missing or illegible when filed -305
1H-tetrazole-1-yl
CH2O(CH2)2SO2CH3




text missing or illegible when filed -306
1H-tetrazole-1-yl
CH2O(CH2)2SOCH2CF3







text missing or illegible when filed -307
1H-tetrazole-1-yl


embedded image









text missing or illegible when filed -308
1H-tetrazole-1-yl


embedded image









text missing or illegible when filed -309
1H-tetrazole-1-yl
CH2O(CH2)2NHSO2CH3




text missing or illegible when filed -310
1H-tetrazole-1-yl
CH2O(CH2)2N(CH3)(SO2CH3)




text missing or illegible when filed -311
1H-tetrazole-2-yl
CH3




text missing or illegible when filed -312
1H-tetrazole-2-yl
CH3




text missing or illegible when filed -313
1H-tetrazole-2-yl
CH2OCH3




text missing or illegible when filed -314
1H-tetrazole-2-yl
CH2OCH2CH3







text missing or illegible when filed -315
1H-tetrazole-2-yl


embedded image









text missing or illegible when filed -316
1H-tetrazole-2-yl
CH2OCH2CH3




text missing or illegible when filed -317
1H-tetrazole-2-yl
CH2SCH3




text missing or illegible when filed -318
1H-tetrazole-2-yl
CH2SCH2CH3







text missing or illegible when filed -319
1H-tetrazole-2-yl


embedded image









text missing or illegible when filed -320
1H-tetrazole-2-yl
CH2SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 104








physical





property


compound


(melting


number
R4
R1
point-ND)







8-321
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2SOCH2



8-322
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2SOCH2CH3






8-323
1H-text missing or illegible when filed -2-text missing or illegible when filed


embedded image








8-324
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2SOCH2CF3



8-325
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2SO2CH3



8-326
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2SO2CH2CH2






8-327
1H-text missing or illegible when filed -2-text missing or illegible when filed


embedded image








8-328
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2SO2CH2CF3



8-329
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2OCH3



8-330
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2OCH2CH3



8-331
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2OCH2CF3



8-332
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2SCH3



8-333
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2SCH2CF3



8-334
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2SOCH3



8-335
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2SOCH2CF3



8-336
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2SO2CH3



8-337
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2SO2CH2CF3






8-338
1H-text missing or illegible when filed -2-text missing or illegible when filed


embedded image








8-339
1H-text missing or illegible when filed -2-text missing or illegible when filed


embedded image








8-340
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2NHSO2CH3



8-341
1H-text missing or illegible when filed -2-text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO2CH3)






text missing or illegible when filed indicates data missing or illegible when filed













TABLE 105









embedded image


















physical





property


compound


(melting point


number
R4
R1
ND)





9-1 
Cl
CH3



9-2 
Cl
CF3



9-3 
Cl
CH2OCH3



9-4 
Cl
CH2OCH2CH3






9-5 
Cl


embedded image








9-6 
Cl
CH2OCH2CF3



9-7 
Cl
CH2SCH3



9-8 
Cl
CH2SCH2CH3






9-9 
Cl


embedded image








9-10
Cl
CH2SCH2CF3



9-11
Cl
CH2SOCH3



9-12
Cl
CH2SOCH2CH3






9-13
Cl


embedded image








9-14
Cl
CH2SOCH2CF3



9-15
Cl
CH2SO2CH3



9-16
Cl
CH2SO2CH2CH3






9-17
Cl


embedded image








9-18
Cl
CH2SO2CH2CF3



9-19
Cl
CH2O(CH2)2OCH3



9-20
Cl
CH2O(CH2)2OCH2CH3



9-21
Cl
CH2O(CH2)2OCH2CF3



9-22
Cl
CH2O(CH2)2SCH3



9-23
Cl
CH2O(CH2)2SCH2CF3



9-24
Cl
CH2O(CH2)2SOCH3



9-25
Cl
CH2O(CH2)2SOCH2CF3



9-26
Cl
CH2O(CH2)2SO2CH3



9-27
Cl
CH2O(CH2)2SO2CH2CF3






9-28
Cl


embedded image








9-29
Cl


embedded image








9-30
Cl
CH2O(CH2)2NHSO2CH3



9-31
Cl
CH2O(CH2)2N(CH3)(SO2CH3)



9-32
SCH3
CH3



9-33
SCH3
CF3



9-34
SCH3
CH2OCH3



9-35
SCH3
CH2OCH2CH3






9-36
SCH3


embedded image








9-37
SCH3
CH2OCH2CF3



9-38
SCH3
CH2SCH3



9-39
SCH3
CH2SCH2CH3






9-40
SCH3


embedded image





















TABLE 106








physical





property


compound


(melting point-


number
R4
R1
ND)







9-41
SCH3
CH2SCH2CF3



9-42
SCH3
CH2SOCH3



9-43
SCH3
CH2SOCH2CH3






9-44
SCH3


embedded image








9-45
SCH3
CH2SOCH2CF3



9-46
SCH3
CH2SO2CH3



9-47
SCH3
CH2SO2CH2CH3






9-48
SCH3


embedded image








9-49
SCH3
CH2SO2CH2CF3



9-50
SCH3
CH2O(CH2)2OCH3



9-51
SCH3
CH2O(CH2)2OCH2CH3



9-52
SCH3
CH2O(CH2)2OCH2CF3



9-53
SCH3
CH2O(CH2)2SCH3



9-54
SCH3
CH2O(CH2)2SCH2CF3



9-55
SCH3
CH2O(CH2)2SOCH3



9-56
SCH3
CH2O(CH2)2SOCH2CF3



9-57
SCH3
CH2O(CH2)2SO2CH3



9-58
SCH3
CH2O(CH2)2SO2CH2CF3






9-59
SCH3


embedded image








9-60
SCH3


embedded image








9-61
SCH3
CH2O(CH2)2NHSO2CH3



9-62
SCH3
CH2O(CH2)2N(CH3)(SO2CH3)



9-63
SCH2CH3
CH3



9-64
SCH2CH3
CF3



9-65
SCH2CH3
CH2OCH3



9-66
SCH2CH3
CH2OCH2CH3






9-67
SCH2CH3


embedded image








9-68
SCH2CH3
CH2OCH2CF3



9-69
SCH2CH3
CH2SCH3



9-70
SCH2CH3
CH2SCH2CH3






9-71
SCH2CH3


embedded image








9-72
SCH2CH3
CH2SCH2CF3



9-73
SCH2CH3
CH2SOCH3



9-74
SCH2CH3
CH2SOCH2CH3






9-75
SCH2CH3


embedded image








9-76
SCH2CH3
CH2SOCH2CF3



9-77
SCH2CH3
CH2SO2CH3



9-78
SCH2CH3
CH2SO2CH2CH3






9-79
SCH2CH3


embedded image








9-80
SCH2CH3
CH2SO2CH2CF3




















TABLE 107









physical






property



compound


(melting point-



number
R4
R1
ND)








9-81
SCH2CH3
CH2O(CH2)2OCH3




9-82
SCH2CH3
CH2O(CH2)2OCH2CH3




9-83
SCH2CH3
CH2O(CH2)2OCH2CF3




9-84
SCH2CH3
CH2O(CH2)2SCH3




9-85
SCH2CH3
CH2O(CH2)2SCH2CF3




9-86
SCH2CH3
CH2O(CH2)2SOCH3




9-87
SCH2CH3
CH2O(CH2)2SOCH2CF3




9-88
SCH2CH3
CH2O(CH2)2SO2CH3




9-89
SCH2CH3
CH2O(CH2)2SO2CH2CF3







9-90
SCH2CH3


embedded image









9-91
SCH2CH3


embedded image









9-92
SCH2CH3
CH2O(CH2)2NHSO2CH3




9-93
SCH2CH3
CH2O(CH2)2N(CH3)(SO2CH3)




9-94
S(CH2)2CH3
CH3




9-95
S(CH2)2CH3
CF3




9-96
S(CH2)2CH3
CH2OCH3




9-97
S(CH2)2CH3
CH2OCH2CH3







9-98
S(CH2)2CH3


embedded image









9-99
S(CH2)2CH3
CH2OCH2CF3




9-100
S(CH2)2CH3
CH2SCH3




9-101
S(CH2)2CH3
CH2SCH2CH3







9-102
S(CH2)2CH3


embedded image









9-103
S(CH2)2CH3
CH2SCH2CF3




9-104
S(CH2)2CH3
CH2SOCH3




9-105
S(CH2)2CH3
CH2SOCH2CH3







9-106
S(CH2)2CH3


embedded image









9-107
S(CH2)2CH3
CH2SOCH2CF3




9-108
S(CH2)2CH3
CH2SO2CH3




9-109
S(CH2)2CH3
CH2SO2CH2CH3







9-110
S(CH2)2CH3


embedded image









9-111
S(CH2)2CH3
CH2SO2CH2CF3




9-112
S(CH2)2CH3
CH2O(CH2)2OCH3




9-113
S(CH2)2CH3
CH2O(CH2)2OCH2CH3




9-114
S(CH2)2CH3
CH2O(CH2)2OCH2CF3




9-115
S(CH2)2CH3
CH2O(CH2)2SCH3




9-116
S(CH2)2CH3
CH2O(CH2)2SCH2CF3




9-117
S(CH2)2CH3
CH2O(CH2)2SOCH3




9-118
S(CH2)2CH3
CH2O(CH2)2SOCH2CF3




9-119
S(CH2)2CH3
CH2O(CH2)2SO2CH3




9-120
S(CH2)2CH3
CH2O(CH2)2SO2CH2CF3



















TABLE 108








physical





property


compound


(melting point-


number
R4
R1
ND)







9-121
S(CH2)2CH3


embedded image








9-122
S(CH2)2CH3


embedded image








9-123
S(CH2)2CH3
CH2O(CH2)2NHSO2CH3



9-124
S(CH2)2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



9-125
SC6H5
CH3



9-126
SC6H5
CF3



9-127
SC6H5
CH2OCH3



9-128
SC6H5
CH2OCH2CH3






9-129
SC6H5


embedded image








9-130
SC6H5
CH2OCH2CF3



9-131
SC6H5
CH2SCH3



9-132
SC6H5
CH2SCH2CH3






9-133
SC6H5


embedded image








9-134
SC6H5
CH2SCH2CF3



9-135
SC6H5
CH2SOCH3



9-136
SC6H5
CH2SOCH2CH3






9-137
SC6H5


embedded image








9-138
SC6H5
CH2SOCH2CF3



9-139
SC6H5
CH2SO2CH3



9-140
SC6H5
CH2SO2CH2CH3






9-141
SC6H5


embedded image








9-142
SC6H5
CH2SO2CH2CF3



9-143
SC6H5
CH2O(CH2)2OCH3



9-144
SC6H5
CH2O(CH2)2OCH2CH3



9-145
SC6H5
CH2O(CH2)2OCH2CF3



9-146
SC6H5
CH2O(CH2)2SCH3



9-147
SC6H5
CH2O(CH2)2SCH2CF3



9-148
SC6H5
CH2O(CH2)2SOCH3



9-149
SC6H5
CH2O(CH2)2SOCH2CF3



9-150
SC6H5
CH2O(CH2)2SO2CH3



9-151
SC6H5
CH2O(CH2)2SO2CH2CF3






9-152
SC6H5


embedded image








9-153
SC6H5


embedded image








9-154
SC6H5
CH2O(CH2)2NHSO2CH3



9-155
SC6H5
CH2O(CH2)2N(CH3)(SO2CH3)



9-156
SCH2C6H5
CH3



9-157
SCH2C6H5
CF3



9-158
SCH2C6H5
CH2OCH3



9-159
SCH2C6H5
CH2OCH2CH3






9-160
SCH2C6H5


embedded image





















TABLE 109








physical





property


compound



text missing or illegible when filed



number
R4
R1
ND)


















9-161
SCH2C6H5
CH2OCH2CF3



9-162
SCH2C6H5
CH2SCH3



9-163
SCH2C6H5
CH2SCH2CH3






9-164
SCH2C6H5


embedded image








9-165
SCH2C6H5
CH2SCH2CF3



9-166
SCH2C6H5
CH2SOCH3



9-167
SCH2C6H5
CH2SOCH2CH3






9-168
SCH2C6H5


embedded image








9-169
SCH2C6H5
CH2SOCH2CF3



9-170
SCH2C6H5
SCH2C6H5



9-171
SCH2C6H5
CH2SO2CH2CH3






9-172
SCH2C6H5


embedded image








9-173
SCH2C6H5
CH2SO2CH2CF3



9-174
SCH2C6H5
CH2O(CH2)2OCH3



9-175
SCH2C6H5
CH2O(CH2)2OCH2CH3



9-176
SCH2C6H5
CH2O(CH2)2OCH2CF3



9-177
SCH2C6H5
CH2O(CH2)2SCH3



9-178
SCH2C6H5
CH2O(CH2)2SCH2CF3



9-179
SCH2C6H5
CH2O(CH2)2SOCH3



9-180
SCH2C6H5
CH2O(CH2)2SOCH2CF3



9-181
SCH2C6H5
CH2O(CH2)2SO2CH3



9-182
SCH2C6H5
CH2O(CH2)2SO2CH2CF3






9-183
SCH2C6H5


embedded image








9-184
SCH2C6H5


embedded image








9-185
SCH2C6H5
CH2O(CH2)2NHSO2CH3



9-186
SCH2C6H5
CH2O(CH2)2N(CH3)(SO2CH3)



9-187
1H-text missing or illegible when filed -1-yl
CH3



9-188
1H-text missing or illegible when filed -1-yl
CF3



9-189
1H-text missing or illegible when filed -1-yl
CH2OCH3



9-190
1H-text missing or illegible when filed -1-yl
CH2OCH2CH3






9-191
1H-text missing or illegible when filed -1-yl


embedded image








9-192
1H-text missing or illegible when filed -1-yl
CH2OCH2CF3



9-193
1H-text missing or illegible when filed -1-yl
CH2SCH3



9-194
1H-text missing or illegible when filed -1-yl
CH2SCH2CH3






9-195
1H-text missing or illegible when filed -1-yl


embedded image








9-196
1H-text missing or illegible when filed -1-yl
CH2SCH2CF3



9-197
1H-text missing or illegible when filed -1-yl
CH2SOCH3



9-198
1H-text missing or illegible when filed -1-yl
CH2OCH2CH3






9-199
1H-text missing or illegible when filed -1-yl


embedded image








9-200
1H-text missing or illegible when filed -1-yl
CH2SOCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 101










physical






property



compound



text missing or illegible when filed




number
R4
R1

text missing or illegible when filed










9-201

text missing or illegible when filed

CH2SO2CH3




9-202

text missing or illegible when filed

CH2SO2CH2CH3








9-203

text missing or illegible when filed



embedded image










9-204

text missing or illegible when filed

CH2SO2CH2CF3




9-205

text missing or illegible when filed

CH2O(CH2)2OCH3




9-206

text missing or illegible when filed

CH2O(CH2)2OCH2CH3




9-207

text missing or illegible when filed

CH2O(CH2)2OCH2CF3




9-208

text missing or illegible when filed

CH2O(CH2)2SCH3




9-209

text missing or illegible when filed

CH2O(CH2)2




9-210

text missing or illegible when filed

CH2O(CH2)2SOCH3




9-211

text missing or illegible when filed

CH2O(CH2)2SOCH2CF3




9-212

text missing or illegible when filed

CH2O(CH2)2SO2CH3




9-213

text missing or illegible when filed

CH2O(CH2)2SO2CH2CF3








9-214

text missing or illegible when filed



embedded image










9-215

text missing or illegible when filed



embedded image










9-216

text missing or illegible when filed

CH2O(CH2)2NHSO2CH3




9-217

text missing or illegible when filed

CH2O(CH2)2N(CH3)(SO2CH3)




9-218

text missing or illegible when filed

CH3




9-219

text missing or illegible when filed

CF3




9-220

text missing or illegible when filed

CH2OCH3




9-221

text missing or illegible when filed

CH2OCH2CH3








9-222

text missing or illegible when filed



embedded image










9-223

text missing or illegible when filed

CH2OCH2CF3




9-224

text missing or illegible when filed

CH2SCH3




9-225

text missing or illegible when filed

CH2SCH2CH3








9-226

text missing or illegible when filed



embedded image










9-227

text missing or illegible when filed

CH2SCH2CF3




9-228

text missing or illegible when filed

CH2SOCH3




9-229

text missing or illegible when filed

CH2SOCH2CH3








9-230

text missing or illegible when filed



embedded image










9-231

text missing or illegible when filed

CH2SOCH2CF3




9-232

text missing or illegible when filed

CH2SO2CH3




9-233

text missing or illegible when filed

CH2SO2CH2CH3








9-234

text missing or illegible when filed



embedded image










9-235

text missing or illegible when filed

CH2SO2CH2CF3




9-236

text missing or illegible when filed

CH2O(CH2)2OCH3




9-237

text missing or illegible when filed

CH2O(CH2)2OCH2CH3




9-238

text missing or illegible when filed

CH2O(CH2)2OCH2CF3




9-239

text missing or illegible when filed

CH2O(CH2)2SCH3




9-240

text missing or illegible when filed

CH2O(CH2)2SCH2CF3








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 111








physical





property


compound


(melting point-


number
R4
R1
ND)







9-241
1H- text missing or illegible when filed
CH2O(CH2)2SOCH3



9-242
1H- text missing or illegible when filed
CH2O(CH2)2SOCH2CF3



9-243
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH3



9-244
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH2CF3






9-245
1H- text missing or illegible when filed


embedded image








9-246
1H- text missing or illegible when filed


embedded image








9-247
1H- text missing or illegible when filed
CH2O(CH2)2NHSO2CH3



9-248
1H- text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO2CH3)



9-249
1H- text missing or illegible when filed
CH3



9-250
1H- text missing or illegible when filed
CF3



9-251
1H- text missing or illegible when filed
CH2OCH3



9-252
1H- text missing or illegible when filed
CH2OCH2CH3






9-253
1H- text missing or illegible when filed


embedded image








9-254
1H- text missing or illegible when filed
CH2OCH2CF3



9-255
1H- text missing or illegible when filed
CH2SCH3



9-256
1H- text missing or illegible when filed
CH2SCH2CH3






9-257
1H- text missing or illegible when filed


embedded image








9-258
1H- text missing or illegible when filed
CH2SCH2CF3



9-259
1H- text missing or illegible when filed
CH2SOCH3



9-260
1H- text missing or illegible when filed
CH2SOCH2CH3






9-261
1H- text missing or illegible when filed


embedded image








9-262
1H- text missing or illegible when filed
CH2SOCH2CF3



9-263
1H- text missing or illegible when filed
CH2SO2CH3



9-264
1H- text missing or illegible when filed
CH2SO2CH2CH3






9-265
1H- text missing or illegible when filed


embedded image








9-266
1H- text missing or illegible when filed
CH2SO2CH2CF3



9-267
1H- text missing or illegible when filed
CH2O(CH2)2OCH3



9-268
1H- text missing or illegible when filed
CH2O(CH2)2OCH2CH3



9-269
1H- text missing or illegible when filed
CH2O(CH2)2OCH2CF3



9-270
1H- text missing or illegible when filed
CH2O(CH2)2SCH3



9-271
1H- text missing or illegible when filed
CH2O(CH2)2SCH2CF3



9-272
1H- text missing or illegible when filed
CH2O(CH2)2SOCH3



9-273
1H- text missing or illegible when filed
CH2O(CH2)2SOCH2CF3



9-274
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH3



9-275
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH2CF3






9-276
1H- text missing or illegible when filed


embedded image








9-277
1H- text missing or illegible when filed


embedded image








9-278
1H- text missing or illegible when filed
CH2O(CH2)2NHSO2CH3



9-279
1H- text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO2CH3)



9-280
1H- text missing or illegible when filed
CH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 112








physical





property


compound


(melting point-


number
R4
R1
ND)







9-281
1H- text missing or illegible when filed
CF3



9-282
1H- text missing or illegible when filed
CH2OCH3



9-283
1H- text missing or illegible when filed
CH2OCH2CH3






9-284
1H- text missing or illegible when filed


embedded image








9-285
1H- text missing or illegible when filed
CH2OCH2CF3



9-286
1H- text missing or illegible when filed
CH2SCH3



9-287
1H- text missing or illegible when filed
CH2SCH2CH3






9-288
1H- text missing or illegible when filed


embedded image








9-289
1H- text missing or illegible when filed
CH2SCH2CF3



9-290
1H- text missing or illegible when filed
CH2SOCH3



9-291
1H- text missing or illegible when filed
CH2SOCH2CH3






9-292
1H- text missing or illegible when filed


embedded image








9-293
1H- text missing or illegible when filed
CH2SOCH2CF3



9-294
1H- text missing or illegible when filed
CH2SO2CH3



9-295
1H- text missing or illegible when filed
CH2SO2CH2CH3






9-296
1H- text missing or illegible when filed


embedded image








9-297
1H- text missing or illegible when filed
CH2SO2CH2CF3



9-298
1H- text missing or illegible when filed
CH2O(CH2)2OCH3



9-299
1H- text missing or illegible when filed
CH2O(CH2)2OCH2CH3



9-300
1H- text missing or illegible when filed
CH2O(CH2)2OCH2CF3



9-301
1H- text missing or illegible when filed
CH2O(CH2)2SCH3



9-302
1H- text missing or illegible when filed
CH2O(CH2)2SCH2CF3



9-303
1H- text missing or illegible when filed
CH2O(CH2)2SOCH3



9-304
1H- text missing or illegible when filed
CH2O(CH2)2SOCH2CF3



9-305
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH3



9-306
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH2CF3






9-307
1H- text missing or illegible when filed


embedded image








9-308
1H- text missing or illegible when filed


embedded image








9-309
1H- text missing or illegible when filed
CH2O(CH2)2NHSO2CH3



9-310
1H- text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO2CH3)



9-311
1H- text missing or illegible when filed
CH3



9-312
1H- text missing or illegible when filed
CF3



9-313
1H- text missing or illegible when filed
CH2OCH3



9-314
1H- text missing or illegible when filed
CH2OCH2CH3






9-315
1H- text missing or illegible when filed


embedded image








9-316
1H- text missing or illegible when filed
CH2OCH2CF3



9-317
1H- text missing or illegible when filed
CH2SCH3



9-318
1H- text missing or illegible when filed
CH2SCH2CH3






9-319
1H- text missing or illegible when filed


embedded image








9-320
1H- text missing or illegible when filed
CH2SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 113








physical





property


compound


(melting


number
R4
R1
point-ND)







9-321
1H-tetrazole-2-yl
CH2SOCH3



9-322
1H-tetrazole-2-yl
CH2SOCH2CH3






9-323
1H-tetrazole-2-yl


embedded image








9-324
1H-tetrazole-2-yl
CH2SOCH2CF3



9-325
1H-tetrazole-2-yl
CH2SO2CH3



9-326
1H-tetrazole-2-yl
CH2SO2CH2CH3






9-327
1H-tetrazole-2-yl


embedded image








9-328
1H-tetrazole-2-yl
CH2SO2CH2CF3



9-329
1H-tetrazole-2-yl
CH2O(CH2)2OCH3



9-330
1H-tetrazole-2-yl
CH2O(CH2)2OCH2CH3



9-331
1H-tetrazole-2-yl
CH2O(CH2)2OCH2CF3



9-332
1H-tetrazole-2-yl
CH2O(CH2)2SCH3



9-333
1H-tetrazole-2-yl
CH2O(CH2)2SCH2CF3



9-334
1H-tetrazole-2-yl
CH2O(CH2)2SOCH3



9-335
1H-tetrazole-2-yl
CH2O(CH2)2SOCH2CF3



9-336
1H-tetrazole-2-yl
CH2O(CH2)2SO2CH3



9-337
1H-tetrazole-2-yl
CH2O(CH2)2SO2CH2CF3






9-338
1H-tetrazole-2-yl


embedded image








9-339
1H-tetrazole-2-yl


embedded image








9-340
1H-tetrazole-2-yl
CH2O(CH2)2NHSO2CH3



9-341
1H-tetrazole-2-yl
CH2O(CH2)2N(CH3)(SO2CH3)
















TABLE 114









embedded image


















physical





property


compound


(melting point-


number
R4
R1
ND)





10-1 
Cl
CH3



10-2 
Cl
CF3



10-3 
Cl
CH2OCH3



10-4 
Cl
CH2OCH2CH3






10-5 
Cl


embedded image








10-6 
Cl
CH2OCH2CF3



10-7 
Cl
CH2SCH3



10-8 
Cl
CH2SCH2CH3






10-9 
Cl


embedded image








10-10
Cl
CH2SCH2CF3



10-11
Cl
CH2SOCH3



10-12
Cl
CH2SOCH2CH3






10-13
Cl


embedded image








10-14
Cl
CH2SOCH2CF3



10-15
Cl
CH2SO2CH3



10-16
Cl
CH2SO2CH2CH3






10-17
Cl


embedded image








10-18
Cl
CH2SO2CH2CF3



10-19
Cl
CH2O(CH2)2OCH3



10-20
Cl
CH2O(CH2)2OCH2CH3



10-21
Cl
CH2O(CH2)2OCH2CF3



10-22
Cl
CH2O(CH2)2SCH3



10-23
Cl
CH2O(CH2)2SCH2CF3



10-24
Cl
CH2O(CH2)2SOCH3



10-25
Cl
CH2O(CH2)2SOCH2CF3



10-26
Cl
CH2O(CH2)2SO2CH3



10-27
Cl
CH2O(CH2)2SO2CH2CF3






10-28
Cl


embedded image








10-29
Cl


embedded image








10-30
Cl
CH2O(CH2)2NHSO2CH3



10-31
Cl
CH2O(CH2)2N(CH3)(SO2CH3)



10-32
SCH3
CH3



10-33
SCH3
CF3



10-34
SCH3
CH2OCH3



10-35
SCH3
CH2OCH2CH3






10-36
SCH3


embedded image








10-37
SCH3
CH2OCH2CF3



10-38
SCH3
CH2SCH3



10-39
SCH3
CH2SCH2CH3






10-40
SCH3


embedded image





















TABLE 115








physical





property


compound


(melting point-


number
R4
R1
ND)







10-41
SCH3
CH2SCH2CF3



10-42
SCH3
CH2SOCH3



10-43
SCH3
CH2SOCH2CH3






10-44
SCH3


embedded image








10-45
SCH3
CH2SOCH2CF3



10-46
SCH3
CH2SO2CH3



10-47
SCH3
CH2SO2CH2CH3






10-48
SCH3


embedded image








10-49
SCH3
CH2SO2CH2CF3



10-50
SCH3
CH2O(CH2)2OCH3



10-51
SCH3
CH2O(CH2)2OCH2CH3



10-52
SCH3
CH2O(CH2)2OCH2CF3



10-53
SCH3
CH2O(CH2)2SCH3



10-54
SCH3
CH2O(CH2)2SCH2CF3



10-55
SCH3
CH2O(CH2)2SOCH3



10-56
SCH3
CH2O(CH2)2SOCH2CF3



10-57
SCH3
CH2O(CH2)2SO2CH3



10-58
SCH3
CH2O(CH2)2SO2CH2CF3






10-59
SCH3


embedded image








10-60
SCH3


embedded image








10-61
SCH3
CH2O(CH2)2NHSO2CH3



10-62
SCH3
CH2O(CH2)2N(CH3)(SO2CH3)



10-63
SCH2CH3
CH3



10-64
SCH2CH3
CF3



10-65
SCH2CH3
CH2OCH3



10-66
SCH2CH3
CH2OCH2CH3






10-67
SCH2CH3


embedded image








10-68
SCH2CH3
CH2OCH2CF3



10-68
SCH2CH3
CH2SCH3



10-70
SCH2CH3
CH2SCH2CH3






10-71
SCH2CH3


embedded image








10-72
SCH2CH3
CH2SCH2CF3



10-73
SCH2CH3
CH2SOCH3



10-74
SCH2CH3
CH2SOCH2CH3






10-75
SCH2CH3


embedded image








10-76
SCH2CH3
CH2SOCH2CF3



10-77
SCH2CH3
CH2SO2CH3



10-78
SCH2CH3
CH2SO2CH2CH3






10-79
SCH2CH3


embedded image








10-80
SCH2CH3
CH2SO2CH2CF3



















TABLE 116








physical





property


compound


(melting point-


number
R4
R1
ND)







10-81 
SCH2CH3
CH2O(CH2)2OCH3



10-82 
SCH2CH3
CH2O(CH2)2OCH2CH3



10-83 
SCH2CH3
CH2O(CH2)2OCH2CF3



10-84 
SCH2CH3
CH2O(CH2)2SCH3



10-85 
SCH2CH3
CH2O(CH2)2SCH2CF3



10-86 
SCH2CH3
CH2O(CH2)2SOCH3



10-87 
SCH2CH3
CH2O(CH2)2SOCH2CF3



10-88 
SCH2CH3
CH2O(CH2)2SO2CH3



10-89 
SCH2CH3
CH2O(CH2)2SO2CH2CF3






10-90 
SCH2CH3


embedded image








10-91 
SCH2CH3


embedded image








10-92 
SCH2CH3
CH2O(CH2)2NHSO2CH3



10-93 
SCH2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



10-94 
S(CH2)2CH3
CH3



10-95 
S(CH2)2CH3
CF3



10-96 
S(CH2)2CH3
CH2OCH3



10-97 
S(CH2)2CH3
CH2OCH2CH3






10-98 
S(CH2)2CH3


embedded image








10-99 
S(CH2)2CH3
CH2OCH2CF3



10-100
S(CH2)2CH3
CH2SCH3



10-101
S(CH2)2CH3
CH2SCH2CH3






10-102
S(CH2)2CH3


embedded image








10-103
S(CH2)2CH3
CH2SCH2CF3



10-104
S(CH2)2CH3
CH2SOCH3



10-105
S(CH2)2CH3
CH2SOCH2CH3






10-106
S(CH2)2CH3


embedded image








10-107
S(CH2)2CH3
CH2SOCH2CF3



10-108
S(CH2)2CH3
CH2SO2CH3



10-109
S(CH2)2CH3
CH2SO2CH2CH3






10-110
S(CH2)2CH3


embedded image








10-111
S(CH2)2CH3
CH2SO2CH2CF3



10-112
S(CH2)2CH3
CH2O(CH2)2OCH3



10-113
S(CH2)2CH3
CH2O(CH2)2OCH2CH3



10-114
S(CH2)2CH3
CH2O(CH2)2OCH2CF3



10-115
S(CH2)2CH3
CH2O(CH2)2SCH3



10-116
S(CH2)2CH3
CH2O(CH2)2SCH2CF3



10-117
S(CH2)2CH3
CH2O(CH2)2SOCH3



10-118
S(CH2)2CH3
CH2O(CH2)2SOCH2CF3



10-119
S(CH2)2CH3
CH2O(CH2)2SO2CH3



10-120
S(CH2)2CH3
CH2O(CH2)2SO2CH2CF3



















TABLE 117








physical





property


compound


(melting


number
R4
R1
point-ND)







10-121
S(CH2)2CH3


embedded image








10-122
S(CH2)2CH3


embedded image








10-123
S(CH2)2CH3
CH2O(CH2)2NHSO2CH3



10-124
S(CH2)2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



10-125
SC6H5
CH3



10-126
SC6H5
CF3



10-127
SC6H5
CH2OCH3



10-128
SC6H5
CH2OCH2CH3






10-129
SC6H5


embedded image








10-130
SC6H5
CH2OCH2CF3



10-131
SC6H5
CH2SCH3



10-132
SC6H5
CH2SCH2CH3






10-133
SC6H5


embedded image








10-134
SC6H5
CH2SCH2CF3



10-135
SC6H5
CH2SOCH3



10-136
SC6H5
CH2SOCH2CH3






10-137
SC6H5


embedded image








10-138
SC6H5
CH2SOCH2CF3



10-139
SC6H5
CH2SO2CH3



10-140
SC6H5
CH2SO2CH2CH3






10-141
SC6H5


embedded image








10-142
SC6H5
CH2SO2CH2CF3



10-143
SC6H5
CH2O(CH2)2OCH3



10-144
SC6H5
CH2O(CH2)2OCH2CH3



10-145
SC6H5
CH2O(CH2)2OCH2CF3



10-146
SC6H5
CH2O(CH2)2SCH3



10-147
SC6H5
CH2O(CH2)2SCH2CF3



10-148
SC6H5
CH2O(CH2)2SOCH3



10-149
SC6H5
CH2O(CH2)2SOCH2CF3



10-150
SC6H5
CH2O(CH2)2SO2CH3



10-151
SC6H5
CH2O(CH2)2SO2CH2CF3






10-152
SC6H5


embedded image








10-153
SC6H5


embedded image








10-154
SC6H5
CH2O(CH2)2NHSO2CH3



10-155
SC6H5
CH2O(CH2)2N(CH3)(SO2CH3)



10-156
SCH2C6H5
CH3



10-157
SCH2C6H5
CF3



10-158
SCH2C6H5
CH2OCH3



10-159
SCH2C6H5
CH2OCH2CH3






10-160
SCH2C6H5


embedded image





















TABLE 118








physical





property





(melting


compound


pointtext missing or illegible when filed  


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed







text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 119








physical





property





(melting


compound


point text missing or illegible when filed


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed







text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 120








physical





property


compound


(melting


number
R4
R1
point-ND)







10-241
1H- text missing or illegible when filed
CH2O(CH2)2SOCH3



10-242
1H- text missing or illegible when filed
CH2O(CH2)2SOCH2CF3



10-243
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH3



10-244
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH2CF3






10-245
1H- text missing or illegible when filed


embedded image








10-246
1H- text missing or illegible when filed


embedded image








10-247
1H- text missing or illegible when filed
CH2O(CH2)2NHSO2CH3



10-248
1H- text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO2CH3)



10-249
1H- text missing or illegible when filed
CH3



10-250
1H- text missing or illegible when filed
CF3



10-251
1H- text missing or illegible when filed
CH2OCH3



10-252
1H- text missing or illegible when filed
CH2OCH2CH3






10-253
1H- text missing or illegible when filed


embedded image








10-254
1H- text missing or illegible when filed
CH2OCH2CF3



10-255
1H- text missing or illegible when filed
CH2SCH3



10-256
1H- text missing or illegible when filed
CH2SCH2CH3






10-257
1H- text missing or illegible when filed


embedded image








10-258
1H- text missing or illegible when filed
CH2SCH2CF3



10-259
1H- text missing or illegible when filed
CH2SOCH3



10-260
1H- text missing or illegible when filed
CH2SOCH2CH3






10-261
1H- text missing or illegible when filed


embedded image








10-262
1H- text missing or illegible when filed
CH2SOCH2CF3



10-263
1H- text missing or illegible when filed
CH2SO2CH3



10-264
1H- text missing or illegible when filed
CH2SO2CH2CH3






10-265
1H- text missing or illegible when filed


embedded image








10-266
1H- text missing or illegible when filed
CH2SO2CH2CF3



10-267
1H- text missing or illegible when filed
CH2O(CH2)2OCH3



10-268
1H- text missing or illegible when filed
CH2O(CH2)2OCH2CH3



10-269
1H- text missing or illegible when filed
CH2O(CH2)2OCH2CF3



10-270
1H- text missing or illegible when filed
CH2O(CH2)2SCH3



10-271
1H- text missing or illegible when filed
CH2O(CH2)2SCH2CF3



10-272
1H- text missing or illegible when filed
CH2O(CH2)2SOCH3



10-273
1H- text missing or illegible when filed
CH2O(CH2)2SOCH2CF3



10-274
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH3



10-275
1H- text missing or illegible when filed
CH2O(CH2)2SO2CH2CF3






10-276
1H- text missing or illegible when filed


embedded image








10-277
1H- text missing or illegible when filed


embedded image








10-278
1H- text missing or illegible when filed
CH2O(CH2)2NHSO2CH3



10-279
1H- text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO2CH3)



10-280
1H- text missing or illegible when filed
CH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 121





compound


physical property


number
R4
R1
(melting point-ND)







10-281
1H-tetrazole-1-yl
CF3



10-282
1H-tetrazole-1-yl
CH2OCH3



10-283
1H-tetrazole-1-yl
CH2OCH2CH3














10-284
1H-tetrazole-1-yl


embedded image








10-285
1H-tetrazole-1-yl
CH2OCH2CF3



10-286
1H-tetrazole-1-yl
CH2SCH3



10-287
1H-tetrazole-1-yl
CH2SCH2CH3






10-288
1H-tetrazole-1-yl


embedded image








10-289
1H-tetrazole-1-yl
CH2SCH2CF3



10-290
1H-tetrazole-1-yl
CH2SOCH3



10-291
1H-tetrazole-1-yl
CH2SOCH2CH3






10-292
1H-tetrazole-1-yl


embedded image








10-293
1H-tetrazole-1-yl
CH2SOCH2CF3



10-294
1H-tetrazole-1-yl
CH2SO2CH3



10-295
1H-tetrazole-1-yl
CH2SO2CH2CH3






10-296
1H-tetrazole-1-yl


embedded image








10-297
1H-tetrazole-1-yl
CH2SO2CH2CF3



10-298
1H-tetrazole-1-yl
CH2O(CH2)2OCH3



10-299
1H-tetrazole-1-yl
CH2O(CH2)2OCH2CH3



10-300
1H-tetrazole-1-yl
CH2O(CH2)2OCH2CF3



10-301
1H-tetrazole-1-yl
CH2O(CH2)2SCH3



10-302
1H-tetrazole-1-yl
CH2O(CH2)2SCH2CF3



10-303
1H-tetrazole-1-yl
CH2O(CH2)2SOCH3



10-304
1H-tetrazole-1-yl
CH2O(CH2)2SOCH2CF3



10-305
1H-tetrazole-1-yl
CH2O(CH2)2SO2CH3



10-306
1H-tetrazole-1-yl
CH2O(CH2)2SO2CH2CF3






10-307
1H-tetrazole-1-yl


embedded image








10-308
1H-tetrazole-1-yl


embedded image








10-309
1H-tetrazole-1-yl
CH2O(CH2)2NHSO2CH3



10-310
1H-tetrazole-1-yl
CH2O(CH2)2N(CH3)(SO2CH3)



10-311
1H-tetrazole-2-yl
CH3



10-312
1H-tetrazole-2-yl
CF3



10-313
1H-tetrazole-2-yl
CH2OCH3



10-314
1H-tetrazole-2-yl
CH2OCH2CH3






10-315
1H-tetrazole-2-yl


embedded image








10-316
1H-tetrazole-2-yl
CH2OCH2CF3



10-317
1H-tetrazole-2-yl
CH2SCH3



10-318
1H-tetrazole-2-yl
CH2SCH2CH3






10-319
1H-tetrazole-2-yl


embedded image








10-320
1H-tetrazole-2-yl
CH2SCH2CF3



















TABLE 122








physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







10-321
1H-tetrazol-2-yl
CH2SOCH3



10-322
1H-tetrazol-2-yl
CH2SOCH2CH3






10-323
1H-tetrazol-2-yl


embedded image








10-324
1H-tetrazol-2-yl
CH2SOCH2CF3



10-325
1H-tetrazol-2-yl
CH2SO2CH3



10-326
1H-tetrazol-2-yl
CH2SO2CH2CH3






10-327
1H-tetrazol-2-yl


embedded image








10-328
1H-tetrazol-2-yl
CH2SO2CH2CF3



10-329
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



10-330
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



10-331
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



10-332
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



10-333
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



10-334
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed OCH3



10-335
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



10-336
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



10-337
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






10-338
1H-tetrazol-2-yl


embedded image








10-339
1H-tetrazol-2-yl


embedded image








10-340
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3






10-341
1H-tetrazol-2-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SO2CH3)






text missing or illegible when filed indicates data missing or illegible when filed













TABLE 123









embedded image


















physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)





11-1
Cl
CH3



11-2
Cl
CF3



11-3
Cl
CH2OCH3



11-4
Cl
CH2OCH2CH3






11-5
Cl


embedded image








11-6
Cl
CH2OCH2CF3



11-7
Cl
CH2SCH3



11-8
Cl
CH2SCH2CH3






11-9
Cl


embedded image








11-10
Cl
CH2SCH2CF3



11-11
Cl
CH2SOCH3



11-12
Cl
CH2SOCH2CH3






11-13
Cl


embedded image








11-14
Cl
CH2SOCH2CF3



11-15
Cl
CH2SO2CH3



11-16
Cl
CH2SO2CH2CH3






11-17
Cl


embedded image








11-18
Cl
CH2SO2CH2CF3



11-19
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



11-20
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



11-21
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



11-22
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



11-23
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



11-24
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



11-25
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



11-26
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



11-27
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






11-28
Cl


embedded image








11-29
Cl


embedded image








11-30
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



11-31
Cl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3)



11-32
SCHtext missing or illegible when filed
CH3



11-33
SCHtext missing or illegible when filed
CF3



11-34
SCHtext missing or illegible when filed
CH2OCH3



11-35
SCHtext missing or illegible when filed
CH2OCH2CH3






11-36
SCHtext missing or illegible when filed


embedded image








11-37
SCHtext missing or illegible when filed
CH2OCH2CF3



11-38
SCHtext missing or illegible when filed
CH2SCH3



11-39
SCHtext missing or illegible when filed
CH2SCH2CH3






11-40
SCHtext missing or illegible when filed


embedded image








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 124








physical


com-


property


pound


(melting


number
R4
R1
point-ND)







11-41
SCH3
CH2SCH2CF text missing or illegible when filed



11-42
SCH3
CH2SOCH text missing or illegible when filed



11-43
SCH3
CH2SOCH text missing or illegible when filed  CH text missing or illegible when filed






11-44
SCH3


embedded image








11-45
SCH3
CH2SOCH text missing or illegible when filed  CF3



11-46
SCH3
CH2SO text missing or illegible when filed  CH3



11-47
SCH3
CH2SO2CH2CH3






11-48
SCH3


embedded image








11-49
SCH3
CH2SO2CH2CF text missing or illegible when filed



11-50
SCH3
CH2O(CH2)2OCH text missing or illegible when filed



11-51
SCH3
CH text missing or illegible when filed  O(CH2)2OCH2CH3



11-52
SCH3
CH text missing or illegible when filed  O(CH2)2OCH2CF text missing or illegible when filed



11-53
SCH3
CH text missing or illegible when filed  O(CH2)2SCH text missing or illegible when filed



11-54
SCH3
CH text missing or illegible when filed  O(CH2)2SCH2CF3



11-55
SCH3
CH2O(CH2)2SOCH text missing or illegible when filed



11-56
SCH3
CH text missing or illegible when filed  O(CH2)2SOCH2CF text missing or illegible when filed



11-57
SCH3
CH2O(CH2)2SO2CH3



11-58
SCH3
CH2O(CH2)2SO2CH2CF3






11-59
SCH3


embedded image








11-60
SCH3


embedded image








11-61
SCH3
CH2O(CH2) text missing or illegible when filed  NHSO2CH text missing or illegible when filed



11-62
SCH3
CH text missing or illegible when filed  O(CH2)2N(CH3)(SO2CH text missing or illegible when filed  )



11-63
SCH2CH3
CH text missing or illegible when filed



11-64
SCH2CH3
CF3



11-65
SCH2CH3
CH2OCH text missing or illegible when filed



11-66
SCH2CH3
CH2OCH2CH text missing or illegible when filed






11-67
SCH2CH3


embedded image








11-68
SCH2CH3
CH2OCH2CF3



11-69
SCH2CH3
CH text missing or illegible when filed  SCH text missing or illegible when filed



11-70
SCH2CH3
CH2SCH text missing or illegible when filed  CH text missing or illegible when filed






11-71
SCH2CH3


embedded image








11-72
SCH2CH3
CH2SCH2C text missing or illegible when filed



11-73
SCH2CH3
CH2SOCH text missing or illegible when filed



11-74
SCH2CH3
CH2SOCH text missing or illegible when filed  CH3






11-75
SCH2CH3


embedded image








11-76
SCH2CH3
CH2SOCH text missing or illegible when filed  CF text missing or illegible when filed



11-77
SCH2CH3
CH2SO2CH text missing or illegible when filed



11-78
SCH2CH3
CH2SO text missing or illegible when filed  CH text missing or illegible when filed  CH3






11-79
SCH2CH3


embedded image








11-80
SCH2CH3
CH2SO text missing or illegible when filed  CH text missing or illegible when filed  CF text missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 125








physical





property





(melting


compound


pointtext missing or illegible when filed


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed








text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image









text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image









text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

SCHtext missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed








text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed


embedded image









text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed








text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed


embedded image









text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed








text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed


embedded image









text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed








text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed


embedded image









text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed





text missing or illegible when filed

S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed

text missing or illegible when filed







text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 126










physical






property



compound


(melting



number
R4
R1
point-ND)










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image










text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 127








physical





property





(melting


compound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







11-161
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2OCH2CF3



11-162
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SCH3



11-163
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SCH2CH3






11-164
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








11-165
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SCH2CF3



11-166
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH3



11-167
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH2CH3






11-168
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








11-169
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH2CF3



11-170
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH3



11-171
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CHtext missing or illegible when filed CH3






11-172
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








11-173
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH2CF3



11-174
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



11-175
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



11-176
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



11-177
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



11-178
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



11-179
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



11-180
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



11-181
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



11-182
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






11-183
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








11- 184
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








11-185
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



11-186
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed SO2CH3)



11-187
1H-pyrazole-1-yl
CH3



11-188
1H-pyrazole-1-yl
CF3



11-189
1H-pyrazole-1-yl
CH2OCH3



11-190
1H-pyrazole-1-yl
CH2OCH2CH3






11-191
1H-pyrazole-1-yl


embedded image








11-192
1H-pyrazole-1-yl
CH2OCH2CF3



11-193
1H-pyrazole-1-yl
CH2SCH3



11-194
1H-pyrazole-1-yl
CH2SCH2CH3






11-195
1H-pyrazole-1-yl


embedded image








11-196
1H-pyrazole-1-yl
CH2SCH2CF3



11-197
1H-pyrazole-1-yl
CH2SOCH3



11-198
1H-pyrazole-1-yl
CH2SOCH2CH3






11-199
1H-pyrazole-1-yl


embedded image








11-200
1H-pyrazole-1-yl
CH2SOCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 128








physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







11-201
1H-pyrazole-1-yl
CH2SO2CH3



11-202
1H-pyrazole-1-yl
CH2SO2CH2CH3






11-203
1H-pyrazole-1-yl


embedded image








11-204
1H-pyrazole-1-yl
CH2SO2CH2CF3



11-205
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



11-206
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



11-207
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



11-208
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



11-209
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



11-210
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed



11-211
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



11-212
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



11-213
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CHtext missing or illegible when filed CF3






11-214
1H-pyrazole-1-yl


embedded image








11-215
1H-pyrazole-1-yl


embedded image








11-216
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



11-217
1H-pyrazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed SO2CH3)



11-218
1H-imidazole-1-yl
CH3



11-219
1H-imidazole-1-yl
CF3



11-220
1H-imidazole-1-yl
CHtext missing or illegible when filed OCH3



11-221
1H-imidazole-1-yl
CHtext missing or illegible when filed OCH2CH3






11-222
1H-imidazole-1-yl


embedded image








11-223
1H-imidazole-1-yl
CHtext missing or illegible when filed OCH2CF3



11-224
1H-imidazole-1-yl
CH2SCH3



11-225
1H-imidazole-1-yl
CH2SCH2CH3






11-226
1H-imidazole-1-yl


embedded image








11-227
1H-imidazole-1-yl
CH2SCH2CF3



11-228
1H-imidazole-1-yl
CH2SOCH3



11-229
1H-imidazole-1-yl
CH2SOCH2CH3






11-230
1H-imidazole-1-yl


embedded image








11-231
1H-imidazole-1-yl
CH2SOCH2CF3



11-232
1H-imidazole-1-yl
CH2SO2CH3



11-233
1H-imidazole-1-yl
CH2SO2CH2CH3






11-234
1H-imidazole-1-yl


embedded image








11-235
1H-imidazole-1-yl
CH2SO2CH2CF3



11-236
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



11-237
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



11-238
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



11-239
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



11-240
1H-imidazole-1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 129








physical





property





(melting


compound


pointtext missing or illegible when filed


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)








text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed







text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 130








physical





property





(melting


compound


point-


number
R4
R1
ND)







11-281
1H-tetrazole-1-yl
CF3



11-282
1H-tetrazole-1-yl
CH2OCH3



11-283
1H-tetrazole-1-yl
CH2OCH2CH3






11-284
1H-tetrazole-1-yl


embedded image








11-285
1H-tetrazole-1-yl
CH2OCH2CF3



11-286
1H-tetrazole-1-yl
CH2SCH3



11-287
1H-tetrazole-1-yl
CH2SCH2CH3






11-288
1H-tetrazole-1-yl


embedded image








11-289
1H-tetrazole-1-yl
CH2SCH2CF3



11-290
1H-tetrazole-1-yl
CH2SOCH3



11-291
1H-tetrazole-1-yl
CH2SOCH2CH3






11-292
1H-tetrazole-1-yl


embedded image








11-293
1H-tetrazole-1-yl
CH2SOCH2CF3



11-294
1H-tetrazole-1-yl
CH2SO2CH3



11-295
1H-tetrazole-1-yl
CH2SO2CH2CH3






11-296
1H-tetrazole-1-yl


embedded image








11-297
1H-tetrazole-1-yl
CH2SO2CH2CF3



11-298
1H-tetrazole-1-yl
CH2O(CH2)2OCH3



11-299
1H-tetrazole-1-yl
CH2O(CH2)2OCH2CH3



11-300
1H-tetrazole-1-yl
CH2O(CH2)2OCH2CF3



11-301
1H-tetrazole-1-yl
CH2O(CH2)2SCH3



11-302
1H-tetrazole-1-yl
CH2O(CH2)2SCH2CF3



11-303
1H-tetrazole-1-yl
CH2O(CH2)2SOCH3



11-304
1H-tetrazole-1-yl
CH2O(CH2)2SOCH2CF3



11-305
1H-tetrazole-1-yl
CH2O(CH2)2SO2CH3



11-306
1H-tetrazole-1-yl
CH2O(CH2)2SO2CH2CF3






11-307
1H-tetrazole-1-yl


embedded image








11-308
1H-tetrazole-1-yl


embedded image








11-309
1H-tetrazole-1-yl
CH2O(CH2)2NHSO2CH3



11-310
1H-tetrazole-1-yl
CH2O(CH2)2N(CH3)(SO2CH3)



11-311
1H-text missing or illegible when filed -1-yl
CH3



11-312
1H-text missing or illegible when filed -1-yl
CF3



11-313
1H-text missing or illegible when filed -1-yl
CH2OCH3



11-314
1H-text missing or illegible when filed -1-yl
CH2OCH2CH3






11-315
1H-text missing or illegible when filed -1-yl


embedded image








11-316
1H-text missing or illegible when filed -1-yl
CH2OCH2CF3



11-317
1H-text missing or illegible when filed -1-yl
CH2SCH3



11-318
1H-text missing or illegible when filed -1-yl
CH2SCH2CH3






11-319
1H-text missing or illegible when filed -1-yl


embedded image








11-320
1H-text missing or illegible when filed -1-yl
CH2SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 146








physical





property


com-


(melting


pound


point-


number
R4
R1
ND)







13-201
1H-pyrazole-1-yl
CH2SO2CH3



13-202
1H-pyrazole-1-yl
CH2SO2CH2CH3






13-203
1H-pyrazole-1-yl


embedded image








13-204
1H-pyrazole-1-yl
CH2SO2CH2CF3



13-205
1H-pyrazole-1-yl
CH2O(CH2)2OCH3



13-206
1H-pyrazole-1-yl
CH2O(CH2)2OCH2CH3



13-207
1H-pyrazole-1-yl
CH2O(CH2)2OCH2CF3



13-208
1H-pyrazole-1-yl
CH2O(CH2)2SCH2



13-209
1H-pyrazole-1-yl
CH2O(CH2)2SCH2CF3



13-210
1H-pyrazole-1-yl
CH2O(CH2)2SOCH2



13-211
1H-pyrazole-1-yl
CH2O(CH2)2SOCH2CF3



13-212
1H-pyrazole-1-yl
CH2O(CH2)2SO2CH3



13-213
1H-pyrazole-1-yl
CH2O(CH2)2SO2CH2CF3






13-214
1H-pyrazole-1-yl


embedded image








13-215
1H-pyrazole-1-yl


embedded image








13-216
1H-pyrazole-1-yl
CH2O(CH2)2NHSO2CH3



13-217
1H-pyrazole-1-yl
CH2O(CH2)2N(CH3)(SO2CH3)



13-218
1H-imidazole-1-yl
CH3



13-219
1H-imidazole-1-yl
CF3



13-220
1H-imidazole-1-yl
CH2OCH3



13-221
1H-imidazole-1-yl
CH2OCH2CH3






13-222
1H-imidazole-1-yl


embedded image








13-223
1H-imidazole-1-yl
CH2OCH2CF3



13-224
1H-imidazole-1-yl
CH2SCH3



13-225
1H-imidazole-1-yl
CH2SCH2CH3






13-226
1H-imidazole-1-yl


embedded image








13-227
1H-imidazole-1-yl
CH2SCH2CF3



13-228
1H-imidazole-1-yl
CH2SOCH3



13-229
1H-imidazole-1-yl
CH2SOCH2CH3






13-230
1H-imidazole-1-yl


embedded image








13-231
1H-imidazole-1-yl
CH2SOCH2CF3



13-232
1H-imidazole-1-yl
CH2SO2CH3



13-233
1H-imidazole-1-yl
CH2SO2CH2CH3






13-234
1H-imidazole-1-yl


embedded image








13-235
1H-imidazole-1-yl
CH2SO2CH2CF3



13-236
1H-imidazole-1-yl
CH2O(CH2)2OCH3



13-237
1H-imidazole-1-yl
CH2O(CH2)2OCH2CH3



13-238
1H-imidazole-1-yl
CH2O(CH2)2OCH2CF3



13-239
1H-imidazole-1-yl
CH2O(CH2)2SCH3



13-240
1H-imidazole-1-yl
CH2O(CH2)2SCH2CF3



















TABLE 147








physical


com-


property


pound


(melting


num-


point-


ber
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







13-241
1H-imidazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



13-242
1H-imidazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



13-243
1H-imidazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



13-244
1H-imidazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






13-245
1H-imidazole-1-yl


embedded image








13-246
1H-imidazole-1-yl


embedded image








13-247
1H-imidazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



13-248
1H-imidazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NH(text missing or illegible when filed SO2CH3)



13-249
1H-triazole-1-yl
CH3



13-250
1H-triazole-1-yl
CF3



13-251
1H-triazole-1-yl
CH2OCH



13-252
1H-triazole-1-yl
CHtext missing or illegible when filed OCH2CH3






13-253
1H-triazole-1-yl


embedded image








13-254
1H-triazole-1-yl
CHtext missing or illegible when filed OCH2CF3



13-255
1H-triazole-1-yl
CH2SCH3



13-256
1H-triazole-1-yl
CHtext missing or illegible when filed SCH2CH3






13-257
1H-triazole-1-yl


embedded image








13-258
1H-triazole-1-yl
CHtext missing or illegible when filed SCH2CF3



13-259
1H-triaole-1-yl
CHtext missing or illegible when filed SOCH3



13-260
1H-triazole-1-yl
CHtext missing or illegible when filed SOCH2CH3






13-261
1H-triazole-1-yl


embedded image








13-262
1H-triazole-1-yl
CHtext missing or illegible when filed SOCH2CF3



13-263
1H-triazole-1-yl
CHtext missing or illegible when filed SO2CH3



13-264
1H-triazole-1-yl
CHtext missing or illegible when filed SOtext missing or illegible when filed CH2CH3






13-265
1H-triazole-1-yl


embedded image








13-266
1H-triazole-1-yl
CHtext missing or illegible when filed SO2CH2CF3



13-267
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



13-268
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



13-269
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



13-270
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



13-271
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



13-272
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



13-273
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



13-274
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



13-275
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






13-276
1H-triazole-1-yl


embedded image








13-277
1H-triazole-1-yl


embedded image








13-278
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



13-279
1H-triazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )N(CHtext missing or illegible when filed )(SO2CH3)



13-280
1H-tetrazole-1-yl
CH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 148








physical





property





(melting


compound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







13-281
1H-tetrazole-1-yl
CF3



13-282
1H-tetrazole-1-yl
CH2OCH3



13-283
1H-tetrazole-1-yl
CH2OCH2CH3






13-284
1H-tetrazole-1-yl


embedded image








13-285
1H-tetrazole-1-yl
CH2OCH2CF3



13-286
1H-tetrazole-1-yl
CHtext missing or illegible when filed SCH3



13-287
1H-tetrazole-1-yl
CH2SCH2CH3






13-288
1H-tetrazole-1-yl


embedded image








13-289
1H-tetrazole-1-yl
CHtext missing or illegible when filed SCH2CF3



13-290
1H-tetrazole-1-yl
CHtext missing or illegible when filed SOCH3



13-291
1H-tetrazole-1-yl
CHtext missing or illegible when filed SOCH2CH3






13-292
1H-tetrazole-1-yl


embedded image








13-293
1H-tetrazole-1-yl
CHtext missing or illegible when filed SOCH2CF3



13-294
1H-tetrazole-1-yl
CHtext missing or illegible when filed SO2CH3



13-295
1H-tetrazole-1-yl
CHtext missing or illegible when filed SO2CHtext missing or illegible when filed CH3






13-296
1H-tetrazole-1-yl


embedded image








13-297
1H-tetrazole-1-yl
CHtext missing or illegible when filed SO2CH2CF3



13-298
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



13-299
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



13-300
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



13-301
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3



13-302
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CF3



13-303
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



13-304
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



13-305
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



13-306
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CHtext missing or illegible when filed CF3






13-307
1H-tetrazole-1-yl


embedded image








13-308
1H-tetrazole-1-yl


embedded image








13-309
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



13-310
1H-tetrazole-1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed SO2CH3)



13-311
1H-tetrazole-2-yl
CH3



13-312
1H-tetrazole-2-yl
CF3



13-313
1H-tetrazole-2-yl
CH2OCH3



13-314
1H-tetrazole-2-yl
CHtext missing or illegible when filed OCH2CH3






13-315
1H-tetrazole-2-yl


embedded image








13-316
1H-tetrazole-2-yl
CHtext missing or illegible when filed OCH2CF3



13-317
1H-tetrazole-2-yl
CHtext missing or illegible when filed SCH3



13-318
1H-tetrazole-2-yl
CHtext missing or illegible when filed SCH2CH3






13-319
1H-tetrazole-2-yl


embedded image








13-320
1H-tetrazole-2-yl
CHtext missing or illegible when filed SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 149










physical






property



compound



text missing or illegible when filed




number

text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed













TABLE 150









embedded image


















physical





property


Compound


(melting


number
R13
R1
point-ND)





14-1 
CH3
CH3



14-2 
CH3
CF3



14-3 
CH3
CH2OCH3



14-4 
CH3
CH2OCH2CH3






14-5 
CH3


embedded image








14-6 
CH3
CH2OCH2CF3



14-7 
CH3
CH2SCH3



14-8 
CH3
CH2SCH2CH3






14-9 
CH3


embedded image








14-10
CH3
CH2SCH2CF3



14-11
CH3
CH2SOCH3



14-12
CH3
CH2SOCH2CH3






14-13
CH3


embedded image








14-14
CH3
CH2SOCH2CF3



14-15
CH3
CH2SO2CH3



14-16
CH3
CH2SO2CH2CH3






14-17
CH3


embedded image








14-18
CH3
CH2SO2CH2CF3



14-19
CH3
CH2O(CH2)2OCH3



14-20
CH3
CH2O(CH2)2OCH2CH3



14-21
CH3
CH2O(CH2)2OCH2CF3



14-22
CH3
CH2O(CH2)2SCH3



14-23
CH3
CH2O(CH2)2SCH2CF3



14-24
CH3
CH2O(CH2)2SOCH3



14-25
CH3
CH2O(CH2)2SOCH2CF3



14-26
CH3
CH2O(CH2)2SO2CH3



14-27
CH3
CH2O(CH2)2SO2CH2CF3






14-28
CH3


embedded image








14-29
CH3


embedded image








14-30
CH3
CH2O(CH2)2NHSO2CH3



14-31
CH3
CH2O(CH2)2N(CH3)(SO2CH3)



14-32
CH2CH3
CH3



14-33
CH2CH3
CF3



14-34
CH2CH3
CH2OCH3



14-35
CH2CH3
CH2OCH2CH3






14-36
CH2CH3


embedded image








14-37
CH2CH3
CH2OCH2CF3



14-38
CH2CH3
CH2SCH3



14-39
CH2CH3
CH2SCH2CH3






14-40
CH2CH3


embedded image























TABLE 151










physical






property



compound


(melting



number
R13
R1
point-ND)









14-41

text missing or illegible when filed


text missing or illegible when filed





14-42

text missing or illegible when filed


text missing or illegible when filed





14-43

text missing or illegible when filed


text missing or illegible when filed









14-44

text missing or illegible when filed



embedded image










14-45

text missing or illegible when filed


text missing or illegible when filed





14-46

text missing or illegible when filed


text missing or illegible when filed





14-47

text missing or illegible when filed


text missing or illegible when filed









14-48

text missing or illegible when filed



embedded image










14-49

text missing or illegible when filed


text missing or illegible when filed





14-50

text missing or illegible when filed


text missing or illegible when filed





14-51

text missing or illegible when filed


text missing or illegible when filed





14-52

text missing or illegible when filed


text missing or illegible when filed





14-53

text missing or illegible when filed


text missing or illegible when filed





14-54

text missing or illegible when filed


text missing or illegible when filed





14-55

text missing or illegible when filed


text missing or illegible when filed





14-56

text missing or illegible when filed


text missing or illegible when filed





14-57

text missing or illegible when filed


text missing or illegible when filed





14-58

text missing or illegible when filed


text missing or illegible when filed









14-59

text missing or illegible when filed



embedded image










14-60

text missing or illegible when filed



embedded image










14-61

text missing or illegible when filed


text missing or illegible when filed





14-62

text missing or illegible when filed


text missing or illegible when filed





14-63

text missing or illegible when filed


text missing or illegible when filed





14-64

text missing or illegible when filed


text missing or illegible when filed





14-65

text missing or illegible when filed


text missing or illegible when filed





14-66

text missing or illegible when filed


text missing or illegible when filed









14-67

text missing or illegible when filed



embedded image










14-68

text missing or illegible when filed


text missing or illegible when filed





14-69

text missing or illegible when filed


text missing or illegible when filed





14-70

text missing or illegible when filed


text missing or illegible when filed









14-71

text missing or illegible when filed



embedded image










14-72

text missing or illegible when filed


text missing or illegible when filed





14-73

text missing or illegible when filed


text missing or illegible when filed





14-74

text missing or illegible when filed


text missing or illegible when filed









14-75

text missing or illegible when filed



embedded image










14-76

text missing or illegible when filed


text missing or illegible when filed





14-77

text missing or illegible when filed


text missing or illegible when filed





14-78

text missing or illegible when filed


text missing or illegible when filed









14-79

text missing or illegible when filed



embedded image










14-80

text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 152








physical





property


compound


(melting


number
R13
R1
point-ND)







14-81
(CH2)2CH3
CH2O(CH2)2OCH3



14-82
(CH2)2CH3
CH2O(CH2)2OCH2CH3



14-83
(CH2)2CH3
CH2O(CH2)2OCH2CF3



14-84
(CH2)2CH3
CH2O(CH2)2SCH3



14-85
(CH2)2CH3
CH2O(CH2)2SCH2CF3



14-86
(CH2)2CH3
CH2O(CH2)2SOCH3



14-87
(CH2)2CH3
CH2O(CH2)2SOCH2CF3



14-88
(CH2)2CH3
CH2O(CH2)2SO2CH3



14-89
(CH2)2CH3
CH2O(CH2)2SO2CH2CF3






14-90
(CH2)2CH3


embedded image








14-91
(CH2)2CH3


embedded image








14-92
(CH2)2CH3
CH2O(CH2)2NHSO2CH3



14-93
(CH2)2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



14-94
CH2CH═CH2
CH3



14-95
CH2CH═CH2
CF3



14-96
CH2CH═CH2
CH2OCH3



14-97
CH2CH═CH2
CH2OCH2CH3






14-98
CH2CH═CH2


embedded image








14-99
CH2CH═CH2
CH2OCH2CF3



14-100
CH2CH═CH2
CH2SCH3



14-101
CH2CH═CH2
CH2SCH2CH3






14-102
CH2CH═CH2


embedded image








14-103
CH2CH═CH2
CH2SCH2CF3



14-104
CH2CH═CH2
CH2SOCH3



14-105
CH2CH═CH2
CH2SOCH2CH3






14-106
CH2CH═CH2


embedded image








14-107
CH2CH═CH2
CH2SOCH2CF3



14-108
CH2CH═CH2
CH2SO2CH3



14-109
CH2CH═CH2
CH2SO2CH2CH3






14-110
CH2CH═CH2


embedded image








14-111
CH2CH═CH2
CH2SO2CH2CF3



14-112
CH2CH═CH2
CH2O(CH2)2OCH3



14-113
CH2CH═CH2
CH2O(CH2)2OCH2CH3



14-114
CH2CH═CH2
CH2O(CH2)2OCH2CF3



14-115
CH2CH═CH2
CH2O(CH2)2SCH3



14-116
CH2CH═CH2
CH2O(CH2)2SCH2CF3



14-117
CH2CH═CH2
CH2O(CH2)2SOCH3



14-118
CH2CH═CH2
CH2O(CH2)2SOCH2CF3



14-119
CH2CH═CH2
CH2O(CH2)2SO2CH3



14-120
CH2CH═CH2
CH2O(CH2)2SO2CH2CF3



















TABLE 153








physical





property


compound


(melting


number
R13
R1
point-ND)







14-121
CH2CH═CH2


embedded image








14-122
CH2CH═CH2


embedded image








14-123
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHtext missing or illegible when filed



14-124
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SOtext missing or illegible when filed CHtext missing or illegible when filed )



14-125
CH2CH═CH2
CH3



14-126
CH2CH═CH2
CF3



14-127
CH2CH═CH2
CHtext missing or illegible when filed OCHtext missing or illegible when filed



14-128
CH2CH═CH2
CHtext missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed






14-129
CH2CH═CH2


embedded image








14-130
CH2CH═CH2
CHtext missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



14-131
CH2CH═CH2
CHtext missing or illegible when filed SCHtext missing or illegible when filed



14-132
CH2CH═CH2
CHtext missing or illegible when filed SCHtext missing or illegible when filed CHtext missing or illegible when filed






14-133
CH2CH═CH2


embedded image








14-134
CH2CH═CH2
CHtext missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



14-135
CH2CH═CH2
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



14-136
CH2CH═CH2
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CHtext missing or illegible when filed






14-137
CH2CH═CH2


embedded image








14-138
CH2CH═CH2
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



14-139
CH2CH═CH2
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



14-140
CH2CH═CH2
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed






14-141
CH2CH═CH2


embedded image








14-142
CH2CH═CH2
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed



14-143
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed



14-144
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed



14-145
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



14-146
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed



14-147
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



14-148
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed



14-149
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



14-150
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



14-151
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed






14-152
CH2CH═CH2


embedded image








14-153
CH2CH═CH2


embedded image








14-154
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHtext missing or illegible when filed



14-155
CH2CH═CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SOtext missing or illegible when filed CHtext missing or illegible when filed )



14-156
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH3



14-157
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CF3



14-158
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed



14-159
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed






14-160
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 154








physical





property


compound


(melting


number
R13
R1
point-ND)







14-161
CH2C6H5
CH2OCH2CF3



14-162
CH2C6H5
CH2SCH3



14-163
CH2C6H5
CH2SCH2CH3






14-164
CH2C6H5


embedded image








14-165
CH2C6H5
CH2SCH2CF3



14-166
CH2C6H5
CH2SOCH3



14-167
CH2C6H5
CH2SOCH2CH3






14-168
CH2C6H5


embedded image








14-169
CH2C6H5
CH2SOCH2CF3



14-170
CH2C6H5
CH2SO2CH3



14-171
CH2C6H5
CH2SO2CH2CH3






14-172
CH2C6H5


embedded image








14-173
CH2C6H5
CH2SO2CH2CF3



14-174
CH2C6H5
CH2O(CH2)2OCH3



14-175
CH2C6H5
CH2O(CH2)2OCH2CH3



14-176
CH2C6H5
CH2O(CH2)2OCH2CF3



14-177
CH2C6H5
CH2O(CH2)2SCH3



14-178
CH2C6H5
CH2O(CH2)2SCH2CF3



14-179
CH2C6H5
CH2O(CH2)2SOCH3



14-180
CH2C6H5
CH2O(CH2)2SOCH2CF3



14-181
CH2C6H5
CH2O(CH2)2SO2CH3



14-182
CH2C6H5
CH2O(CH2)2SO2CH2CF3






14-183
CH2C6H5


embedded image








14-184
CH2C6H5


embedded image








14-185
CH2C6H5
CH2O(CH2)2NHSO2CH3



14-186
CH2C6H5
CH2O(CH2)2N(CH3)(SO2CH3)



14-187
SO2CH3
CH3



14-188
SO2CH3
CF3



14-189
SO2CH3
CH2OCH3



14-190
SO2CH3
CH2OCH2CH3



14-191
SO2CH3


embedded image





14-192
SO2CH3
CH2OCH2CF3



14-193
SO2CH3
CH2SCH3



14-194
SO2CH3
CH2SCH2CH3






14-195
SO2CH3


embedded image








14-196
SO2CH3
CH2SCH2CF3



14-197
SO2CH3
CH2SOCH3



14-198
SO2CH3
CH2SOCH2CH3






14-199
SO2CH3


embedded image








14-200
SO2CH3
CH2SOCH2CF3



















TABLE 155








physical





property


compound


(melting


number
R12
R1
point-ND)








text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed




text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed







text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 156








physical





property


compound


(melting


number
R13
R1
point-ND)







14-241
SO2CH2CH3
CH2O(CH2)2SOCH3



14-242
SO2CH2CH3
CH2O(CH2)2SOCH2CF3



14-243
SO2CH2CH3
CH2O(CH2)2SO2CH3



14-244
SO2CH2CH3
CH2O(CH2)2SO2CH2CF3






14-245
SO2CH2CH3


embedded image








14-246
SO2CH2CH3


embedded image








14-247
SO2CH2CH3
CH2O(CH2)2NHSO2CH3



14-248
SO2CH2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



14-249
SO2(CH2)2CH3
CH3



14-250
SO2(CH2)2CH3
CF3



14-251
SO2(CH2)2CH3
CH2OCH3



14-252
SO2(CH2)2CH3
CH2OCH2CH3






14-253
SO2(CH2)2CH3


embedded image








14-254
SO2(CH2)2CH3
CH2OCH2CF3



14-255
SO2(CH2)2CH3
CH2SCH3



14-256
SO2(CH2)2CH3
CH2SCH2CH3






14-257
SO2(CH2)2CH3


embedded image








14-258
SO2(CH2)2CH3
CH2SCH2CF3



14-259
SO2(CH2)2CH3
CH2SOCH3



14-260
SO2(CH2)2CH3
CH2SOCH2CH3






14-261
SO2(CH2)2CH3


embedded image








14-262
SO2(CH2)2CH3
CH2SOCH2CF3



14-263
SO2(CH2)2CH3
CH2SO2CH3



14-264
SO2(CH2)2CH3
CH2SO2CH2CH3






14-265
SO2(CH2)2CH3


embedded image








14-266
SO2(CH2)2CH3
CH2SO2CH2CF3



14-267
SO2(CH2)2CH3
CH2O(CH2)2OCH3



14-268
SO2(CH2)2CH3
CH2O(CH2)2OCH2CH3



14-269
SO2(CH2)2CH3
CH2O(CH2)2OCH2CF3



14-270
SO2(CH2)2CH3
CH2O(CH2)2SCH3



14-271
SO2(CH2)2CH3
CH2O(CH2)2SCH2CF3



14-272
SO2(CH2)2CH3
CH2O(CH2)2SOCH3



14-273
SO2(CH2)2CH3
CH2O(CH2)2SOCH2CF3



14-274
SO2(CH2)2CH3
CH2O(CH2)2SO2CH3



14-275
SO2(CH2)2CH3
CH2O(CH2)2SO2CH2CF3






14-276
SO2(CH2)2CH3


embedded image








14-277
SO2(CH2)2CH3


embedded image








14-278
SO2(CH2)2CH3
CH2O(CH2)2NHSO2CH3



14-279
SO2(CH2)2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



14-280
SO2C6H5
CH3



















TABLE 157








physical





property





(melting


compound


point-


number
R13
R1
ND)







14-281
SO2C6H5
CF3



14-282
SO2C6H5
CH2OCH3



14-283
SO2C6H5
CH2OCH2CH3






14-284
SO2C6H5


embedded image








14-285
SO2C6H5
CH2OCH2CF3



14-286
SO2C6H5
CH2SCH3



14-287
SO2C6H5
CH2SCH2CH3






14-288
SO2C6H5


embedded image








14-289
SO2C6H5
CH2SCH2CF3



14-290
SO2C6H5
CH2SOCH3



14-291
SO2C6H5
CH2SOCH2CH3






14-292
SO2C6H5


embedded image








14-293
SO2C6H5
CH2SOCH2CF3



14-294
SO2C6H5
CH2SO2CH3



14-295
SO2C6H5
CH2SO2CH2CH3






14-296
SO2C6H5


embedded image








14-297
SO2C6H5
CH2SO2CH2CF3



14-298
SO2C6H5
CH2O(CH2)2OCH3



14-299
SO2C6H5
CH2O(CH2)2OCH2CH3



14-300
SO2C6H5
CH2O(CH2)2OCH2CF3



14-301
SO2C6H5
CH2O(CH2)2SCH3



14-302
SO2C6H5
CH2O(CH2)2SCH2CF3



14-303
SO2C6H5
CH2O(CH2)2SOCH3



14-304
SO2C6H5
CH2O(CH2)2SOCH2CF3



14-305
SO2C6H5
CH2O(CH2)2SO2CH3



14-306
SO2C6H5
CH2O(CH2)2SO2CH2CF3






14-307
SO2C6H5


embedded image








14-308
SO2C6H5


embedded image








14-309
SO2C6H5
CH2O(CH2)2NHSO2CH3



14-310
SO2C6H5
CH2O(CH2)2N(CH3)(SO2CH3)



14-311
SO2(4-CH3)C6H text missing or illegible when filed
CH3



14-312
SO2(4-CH3)C6H text missing or illegible when filed
CF3



14-313
SO2(4-CH3)C6H text missing or illegible when filed
CH2OCH3



14-314
SO2(4-CH3)C6H text missing or illegible when filed
CH2OCH2CH3






14-315
SO2(4-CH3)C6H4


embedded image








14-316
SO2(4-CH3)C6H text missing or illegible when filed
CH2OCH2CF3



14-317
SO2(4-CH3)C6H text missing or illegible when filed
CH2SCH3



14-318
SO2(4-CH3)C6H text missing or illegible when filed
CH2SCH2CH3






14-319
SO2(4-CH3)C6H4


embedded image








14-320
SO2(4-CH3)C6H text missing or illegible when filed
CH2SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 158








physical





property


com-


(melting


pound


point-


number
R13
R1
ND)







14-321
SO2(4-CH3)C6H4
CH2SOCH3



14-322
SO2(4-CH3)C6H4
CH2SOCH2CH3






14-323
SO2(4-CH3)C6H4


embedded image








14-324
SO2(4-CH3)C6H4
CH2SOCH2CF3



14-325
SO2(4-CH3)C6H4
CH2SO2CH3



14-326
SO2(4-CH3)C6H4
CH2SO2CH2CH3






14-327
SO2(4-CH3)C6H4


embedded image








14-328
SO2(4-CH3)C6H4
CH2SO2CH2CF3



14-329
SO2(4-CH3)C6H4
CH2O(CH2)2OCH3



14-330
SO2(4-CH3)C6H4
CH2(CH2)2OCH2CH3



14-331
SO2(4-CH3)C6H4
CH2(CH2)2OCH2CF3



14-332
SO2(4-CH3)C6H4
CH2O(CH2)2SCH3



14-333
SO2(4-CH3)C6H4
CH2O(CH2)2SCH2CF3



14-334
SO2(4-CH3)C6H4
CH2O(CH2)2SOCH3



14-335
SO2(4-CH3)C6H4
CH2O(CH2)2SOCH2CF3



14-336
SO2(4-CH3)C6H4
CH2O(CH2)2SO2CH3



14-337
SO2(4-CH3)C6H4
CH2O(CH2)2SO2CH2CF3






14-338
SO2(4-CH3)C6H4


embedded image








14-339
SO2(4-CH3)C6H4


embedded image








14-340
SO2(4-CH3)C6H4
CH2O(CH2)2NHSO2CH3



14-341
SO2(4-CH3)C6H text missing or illegible when filed
CH2O(CH2)2N(CH3)(SO text missing or illegible when filed CH3)



14-342
COCH3
CH3



14-343
COCH3
CF3



14-344
COCH3
CH2OCH3



14-345
COCH3
CH2OCH2CH3






14-346
COCH3


embedded image








14-347
COCH3
CH2OCH2CF3



14-348
COCH3
CH2SCH3



14-349
COCH3
CH2SCH2CH3






14-350
COCH3


embedded image








14-351
COCH3
CH2SCH2CF3



14-352
COCH3
CH2SOCH3



14-353
COCH3
CH2SOCH2CH3






14-354
COCH3


embedded image








14-355
COCH3
CH2SOCH2CF3



14-356
COCH3
CH2SO2CH3



14-357
COCH3
CH2SO2CH2CH3






14-358
COCH3


embedded image








14-359
COCH3
CH2SO2CH2CF3



14-360
COCH3
CH2O(CH2)2OCH3






text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 159










physical






property



compound


(melting



number
R text missing or illegible when filed
R1
point text missing or illegible when filed )










text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image










text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 160








physical





property


compound


(melting


number
R13
R1
point-ND







14-401
COC6H5


embedded image








14-402
COC6H5
CH2O(CH2)2NHSO2CH3



14-403
COC6H5
CH2O(CH2)2N(CH3)(SO2CH3)



14-404
COCH2C6H5
CH3



14-405
COCH2C6H5
CF3



14-405
COCH2C6H5
CH2OCH3



14-407
COCH2C6H5
CH2OCH2CH3






14-408
COCH2C6H5


embedded image








14-409
COCH2C6H5
CH2OCH2CF3



14-410
COCH2C6H5
CH2SCH3



14-411
COCH2C6H5
CH2SCH2CH3






14-412
COCH2C6H5


embedded image








14-413
COCH2C6H5
CH2SCH2CF3



14-414
COCH2C6H5
CH2SOCH3



14-415
COCH2C6H5
CH2SOCH2CH3






14-416
COCH2C6H5


embedded image








14-417
COCH2C6H5
CH2SOCH2CF3



14-418
COCH2C6H5
CH2SO2CH3



14-419
COCH2C6H5
CH2SO2CH2CH3






14-420
COCH2C6H5


embedded image








14-421
COCH2C6H5
CH2SO2CH2CF3



14-422
COCH2C6H5
CH2O(CH2)2OCH3



14-423
COCH2C6H5
CH2O(CH2)2OCH2CH3



14-424
COCH2C6H5
CH2O(CH2)2OCH2CF3



14-425
COCH2C6H5
CH2O(CH2)2SCH3



14-426
COCH2C6H5
CH2O(CH2)2SCH2CF3



14-427
COCH2C6H5
CH2O(CH2)2SOCH3



14-428
COCH2C6H5
CH2O(CH2)2SOCH2CF3



14-429
COCH2C6H5
CH2O(CH2)2SO2CH3



14-430
COCH2C6H5
CH2O(CH2)2SO2CH2CF3






14-431
COCH2C6H5


embedded image








14-432
COCH2C6H5


embedded image








14-433
COCH2C6H5
CH2O(CH2)2NHSO2CH3



14-434
COCH2C6H5
CH2O(CH2)2N(CH3)(SO2CH3)



 4-435
CH2COCH3
CH3



 4-436
CH2COCH3
CF3



 4-437
CH2COCH3
CH2OCH3



 4-438
CH2COCH3
CH2OCH2CH3






 4-439
CH2COCH3


embedded image








 4-439
CH2COCH3
CH2OCH2CF3



















TABLE 131








physical





property


compound



text missing or illegible when filed



number
R4
R1

text missing or illegible when filed








11-321

text missing or illegible when filed

CH2SOCH3



11-322

text missing or illegible when filed

CH2SOCH2CH3






11-323

text missing or illegible when filed



embedded image








11-324

text missing or illegible when filed

CH2SOCH2CF3



11-325

text missing or illegible when filed

CH2SO2CH3



11-326

text missing or illegible when filed

CH2SO2CH2CH3






11-327

text missing or illegible when filed



embedded image








11-328

text missing or illegible when filed

CH2SO2CH2CF3



11-329

text missing or illegible when filed

CH2O(CH2)2OCH3



11-330

text missing or illegible when filed

CH2O(CH2)2OCH2CH3



11-331

text missing or illegible when filed

CH2O(CH2)2OCH2CF3



11-332

text missing or illegible when filed

CH2O(CH2)2SCH3



11-333

text missing or illegible when filed

CH2O(CH2)2SCH2CF3



11-334

text missing or illegible when filed

CH2O(CH2)2SOCH3



11-335

text missing or illegible when filed

CH2O(CH2)2SOCH2CF3



11-336

text missing or illegible when filed

CH2O(CH2)2SO2CH3



11-337

text missing or illegible when filed

CH2O(CH2)2SO2CH2CF3






11-338

text missing or illegible when filed



embedded image








11-339

text missing or illegible when filed



embedded image








11-340

text missing or illegible when filed

CH2O(CH2)2NHSO2CH3



11-341

text missing or illegible when filed

CH2O(CH2)2N(CH3)(SO2CH3)






text missing or illegible when filed indicates data missing or illegible when filed













TABLE 132









embedded image




















physical






property



compound


(melting



number
R4
R1
point-ND)







12-1
Cl
CH3




12-2
Cl
CF3




12-3
Cl
CH2OCH3




12-4
Cl
CH2OCH2CH3








12-5
Cl


embedded image










12-6
Cl
CH2OCH2CF3




12-7
Cl
CH2SCH3




12-8
Cl
CH2SCH2CH3








12-9
Cl


embedded image










12-10
Cl
CH2SCH2CF3




12-11
Cl
CH2SOCH3




12-12
Cl
CH2SOCH2CH3








12-13
Cl


embedded image










12-14
Cl
CH2SOCH2CF3




12-15
Cl
CH2SO2CH3




12-16
Cl
CH2SO2CH2CH3








12-17
Cl


embedded image










12-18
Cl
CH2SO2CH2CF3




12-19
Cl
CH2O(CH2)2OCH3




12-20
Cl
CH2O(CH2)2OCH2CH3




12-21
Cl
CH2O(CH2)2OCH2CF3




12-22
Cl
CH2O(CH2)2SCH3




12-23
Cl
CH2O(CH2)2SCH2CF3




12-24
Cl
CH2O(CH2)2SOCH3




12-25
Cl
CH2O(CH2)2SOCH2CF3




12-26
Cl
CH2O(CH2)2SO2CH3




12-27
Cl
CH2O(CH2)2SO2CH2CF3








12-28
Cl


embedded image










12-29
Cl


embedded image










12-30
Cl
CH2O(CH2)2NHSO2CH3




12-31
Cl
CH2O(CH2)2N(CH3)(SO2CH3)




12-32
SCH3
CH3




12-33
SCH3
CF3




12-34
SCH3
CH2OCH3




12-35
SCH3
CH2OCH2CH3








12-36
SCH3


embedded image










12-37
SCH3
CH2OCH2CF3




12-38
SCH3
CH2SCH3




12-39
SCH3
CH2SCH2CH3








12-40
SCH3


embedded image






















TABLE 133








physical





property


compound


(melting


number
R4
R1
point-ND)







12-41
SCH3
CH2SCH2CF3



12-42
SCH3
CH2SOCH3



12-43
SCH3
CH2SOCH2CH3






12-44
SCH3


embedded image








12-45
SCH3
CH2SOCH2CF3



12-46
SCH3
CH2SO2CH3



12-47
SCH3
CH2SO2CH2CH3






12-48
SCH3


embedded image








12-49
SCH3
CH2SO2CH2CF3



12-50
SCH3
CH2O(CH2)2OCH3



12-51
SCH3
CH2O(CH2)2OCH2CH3



12-52
SCH3
CH2O(CH2)2OCH2CF3



12-53
SCH3
CH2O(CH2)2SCH3



12-54
SCH3
CH2O(CH2)2SCH2CF3



12-55
SCH3
CH2O(CH2)2SOCH3



12-56
SCH3
CH2O(CH2)2SOCH2CF3



12-57
SCH3
CH2O(CH2)2SO2CH3



12-58
SCH3
CH2O(CH2)2SO2CH2CF3






12-59
SCH3


embedded image








12-60
SCH3


embedded image








12-61
SCH3
CH2O(CH2)2NHSO2CH3



12-62
SCH3
CH2O(CH2)2N(CH3)(SO2CH3)



12-63
SCH2CH3
CH3



12-64
SCH2CH3
CF3



12-65
SCH2CH3
CH2OCH3



12-66
SCH2CH3
CH2OCH2CH3






12-67
SCH2CH3


embedded image








12-68
SCH2CH3
CH2OCH2CF3



12-69
SCH2CH3
CH2SCH3



12-70
SCH2CH3
CH2SCH2CH3






12-71
SCH2CH3


embedded image








12-72
SCH2CH3
CH2SOCH2CH3



12-73
SCH2CH3
CH2SO2CH3



12-74
SCH2CH3
CH2SOCH2CH3






12-75
SCH2CH3


embedded image








12-76
SCH2CH3
CH2SOCH2CF3



12-77
SCH2CH3
CH2SO2CH3



12-78
SCH2CH3
CH2SO2CH2CH3






12-79
SCH2CH3


embedded image








12-80
SCH2CH3
CH2SO2CH2CF3



















TABLE 134








physical





property


compound


(melting point


number
R text missing or illegible when filed
R1

text missing or illegible when filed )








text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed







text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 135








physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







12-121
S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed


embedded image








12-122
S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed


embedded image








12-123


text missing or illegible when filed CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHtext missing or illegible when filed



12-124
S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed



12-125
SCtext missing or illegible when filed Htext missing or illegible when filed
CH3



12-126
SCtext missing or illegible when filed Htext missing or illegible when filed
CF3



12-127
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2OCH3



12-128
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCH2CH3






12-129
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-130
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCH2CF3



12-131
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SCH3



12-132
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CH3






12-133
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-134
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CF3



12-135
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



12-136
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CHtext missing or illegible when filed






12-137
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-138
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCH2CF3



12-139
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SO2CH3



12-140
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CH2CH3






12-141
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-142
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SO2CH2CF3



12-143
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



12-144
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed



12-145
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



12-146
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed Otext missing or illegible when filed (CHtext missing or illegible when filed )text missing or illegible when filed SCH3



12-147
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH2CF3



12-148
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



12-149
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3



12-150
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



12-151
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CF3






12-152
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-153
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-154
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



12-155
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed (SO2CH3)



12-156
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH3



12-157
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CF3



12-158
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH2OCH3



12-159
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH2OCH2CH3






12-160
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 136








physi-





cal





prop-


com-


erty


pound


(melt-


num-


ing text missing or illegible when filed


ber
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







12-161
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



12-162
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed



12-163
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CHtext missing or illegible when filed






12-164
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-165
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



12-166
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



12-167
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CHtext missing or illegible when filed






12-168
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-169
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



12-170
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



12-171
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed






12-172
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-173
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed



12-174
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed



12-175
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed



12-176
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filedtext missing or illegible when filedtext missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



12-177
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed



12-178
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



12-179
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed



12-180
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



12-181
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



12-182
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed






12-183
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-184
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-185
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



12-186
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed )



12-187
1H-pyrazole-1-yl
CHtext missing or illegible when filed



12-188
1H-pyrazole-1-yl
CFtext missing or illegible when filed



12-189
1H-pyrazole-1-yl
CHtext missing or illegible when filed OCHtext missing or illegible when filed



12-190
1H-pyrazole-1-yl
CHtext missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed






12-191
1H-pyrazole-1-yl


embedded image








12-192
1H-pyrazole-1-yl
CHtext missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



12-193
1H-pyrazole-1-yl
CHtext missing or illegible when filed SCHtext missing or illegible when filed



12-194
1H-pyrazole-1-yl
CHtext missing or illegible when filed SCHtext missing or illegible when filed CHtext missing or illegible when filed






12-195
1H-pyrazole-1-yl


embedded image








12-196
1H-pyrazole-1-yl
CHtext missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



12-197
1H-pyrazole-1-yl
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



12-198
1H-pyrazole-1-yl
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CHtext missing or illegible when filed






12-199
1H-pyrazole-1-yl


embedded image








12-200
1H-pyrazole-1-yl
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 137








physical





property





(melting


compound


point-


number
R4
R1
ND)







12-201
1H-text missing or illegible when filed -1-yl
CH2SO2CH3



12-202
1H-text missing or illegible when filed -1-yl
CH2SO2CH2CH3






12-203
1H-text missing or illegible when filed -1-yl


embedded image








12-204
1H-text missing or illegible when filed -1-yl
CH2SO2CH2CF3



12-205
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH3



12-206
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH2CH3



12-207
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH2CF3



12-208
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SCH3



12-209
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SCH2CF3



12-210
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SOCH3



12-211
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SOCH2CF3



12-212
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SO2CH3



12-213
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SO2CH2CF3






12-214
1H-text missing or illegible when filed -1-yl


embedded image








12-215
1H-text missing or illegible when filed -1-yl


embedded image








12-216
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2NHSO2CH3



12-217
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2N(CH3)(SO2CH3)



12-218
1H-text missing or illegible when filed -1-yl
CH3



12-219
1H-text missing or illegible when filed -1-yl
CF3



12-220
1H-text missing or illegible when filed -1-yl
CH2OCH3



12-221
1H-text missing or illegible when filed -1-yl
CH2OCH2CH3






12-222
1H-text missing or illegible when filed -1-yl


embedded image








12-223
1H-text missing or illegible when filed -1-yl
CH2OCH2CF3



12-224
1H-text missing or illegible when filed -1-yl
CH2SCH3



12-225
1H-text missing or illegible when filed -1-yl
CH2SCH2CH3






12-226



embedded image








12-227
1H-text missing or illegible when filed -1-yl
CH2SCHtext missing or illegible when filed CF3



12-228
1H-text missing or illegible when filed -1-yl
CH2SOCH3



12-229
1H-text missing or illegible when filed -1-yl
CH2SOCH2CH3






12-230
1H-text missing or illegible when filed -1-yl


embedded image








12-231
1H-text missing or illegible when filed -1-yl
CH2SOCH2CF3



12-232
1H-text missing or illegible when filed -1-yl
CH2SO2CH3



12-233
1H-text missing or illegible when filed -1-yl
CH2SO2CH2CH3






12-234
1H-text missing or illegible when filed -1-yl


embedded image








12-235
1H-text missing or illegible when filed -1-yl
CH2SO2CH2CF3



12-236
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH3



12-237
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH2CH3



12-238
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2OCH2CF3



12-239
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SCH3



12-240
1H-text missing or illegible when filed -1-yl
CH2O(CH2)2SCH2CF3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 138








physical


com-


property


pound


(text missing or illegible when filed


number

text missing or illegible when filed

R1

text missing or illegible when filed









text missing or illegible when filed

1H-imidazole-
CHtext missing or illegible when filed CH(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed




1-yl





text missing or illegible when filed

1H-imidazole-
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH2CF3




1-yl





text missing or illegible when filed

1H-imidazole-
CH2O(CH2)SO2CH3




1-yl





text missing or illegible when filed

1H-imidazole-
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH2CFtext missing or illegible when filed




1-yl








text missing or illegible when filed

1H-imidazole- 1-yl


embedded image









text missing or illegible when filed

1H-imidazole- 1-yl


embedded image









text missing or illegible when filed

1H-imidazole-
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3




1-yl





text missing or illegible when filed

1H-imidazole-
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )text missing or illegible when filed (SO2CH3)




1-yl





text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CFtext missing or illegible when filed




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2OCH3




text missing or illegible when filed

1H--1-yl
CH2OCHtext missing or illegible when filed CHtext missing or illegible when filed







text missing or illegible when filed

1H--text missing or illegible when filed 1-yl


embedded image









text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CHtext missing or illegible when filed OCH2CF3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2SCH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2SCH2CH3







text missing or illegible when filed

1H-text missing or illegible when filed -1-yl


embedded image









text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2SCH2CF3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2SOCH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CHtext missing or illegible when filed SOCH2CH3







text missing or illegible when filed

1H-text missing or illegible when filed -1-yl


embedded image









text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2SOCH2CF3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2SO2CH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2SO2CHtext missing or illegible when filed CH3







text missing or illegible when filed

1H-text missing or illegible when filed -1-yl


embedded image









text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2SO2CH2CF3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SCH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH2O(CH2)3OCH2CF3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CH2CF3







text missing or illegible when filed

1H-text missing or illegible when filed -1-yl


embedded image









text missing or illegible when filed

1H-text missing or illegible when filed -1-yl


embedded image












text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )text missing or illegible when filed (SO2CH3)




text missing or illegible when filed

1H-text missing or illegible when filed -1-yl
CH3






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 139








physical





property


compound


(melting pointtext missing or illegible when filed


number
Rtext missing or illegible when filed
R1
ND)








text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed







text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 140








physical





property


compound


(melting


number
R4
R1
point-ND)







12-321
1H-tetrazole-2-yl
CH2SOCH3



12-322
1H-tetrazole-2-yl
CH2SOCH2CH3






12-323
1H-tetrazole-2-yl


embedded image








12-324
1H-tetrazole-2-yl
CH2SOCH2CF3



12-325
1H-tetrazole-2-yl
CH2SO2CH3



12-326
1H-tetrazole-2-yl
CH2SO2CH2CH3






12-327
1H-tetrazole-2-yl


embedded image








12-328
1H-tetrazole-2-yl
CH2SO2CH2CF3



12-329
1H-tetrazole-2-yl
CH2O(CH2)2OCH3



12-330
1H-tetrazole-2-yl
CH2O(CH2)2OCH2CH3



12-331
1H-tetrazole-2-yl
CH2O(CH2)2OCH2CF3



12-332
1H-tetrazole-2-yl
CH2O(CH2)2SCH3



12-333
1H-tetrazole-2-yl
CH2O(CH2)2SCH2CF3



12-334
1H-tetrazole-2-yl
CH2O(CH2)2SOCH3



12-335
1H-tetrazole-2-yl
CH2O(CH2)2SOCH2CF3



12-336
1H-tetrazole-2-yl
CH2O(CH2)2SO2CH3



12-337
1H-tetrazole-2-yl
CH2O(CH2)2SO2CH2CF3






12-338
1H-tetrazole-2-yl


embedded image








12-339
1H-tetrazole-2-yl


embedded image








12-340
1H-tetrazole-2-yl
CH2O(CH2)2NHSO2CH3



12-341
1H-tetrazole-2-yl
CH2O(CH2)2N(CH3)(SO2CH3)
















TABLE 141









embedded image


















physical





property


compound


(melting point-


number
R4
R1
ND)






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image









text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed





text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed








text missing or illegible when filed


text missing or illegible when filed



embedded image








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 142








physical





property





(melting


compound


point-


number
R4
R1
ND)







13-41
SCH3
CH2SCH2CF3



13-42
SCH3
CH2SOCH3



13-43
SCH3
CH2SOCH2CH3






13-44
SCH3


embedded image








13-45
SCH3
CH2SOCH2CF3



13-46
SCH3
CH2SO2CH3



13-47
SCH3
CH2SO2CH2CH3






13-48
SCH3


embedded image








13-49
SCH3
CH2SO2CH2CF3



13-50
SCH3
CH2SO2CH2CF3



13-51
SCH3
CH2O(CH2)2OCH2CH3



13-52
SCH3
CH2O(CH2)2OCH2CF3



13-53
SCH3
CH2O(CH2)2SCH3



13-54
SCH3
CH2O(CH2)2SCH2CF3



13-55
SCH3
CH2O(CH2)2SOCH3



13-56
SCH3
CH2O(CH2)2SOCH2CF3



13-57
SCH3
CH2O(CH2)2SO2CH3



13-58
SCH3
CH2O(CH2)2SO2CH2CF3






13-59
SCH3


embedded image








13-60
SCH3


embedded image








13-61
SCH3
CH2O(CH2)2NHSO2CH3



13-62
SCH3
CH2O(CH2)2N(CH3)(SO2CH3)



13-63
SCH2CH3
CH3



13-64
SCH2CH3
CF3



13-65
SCH2CH3
CH2OCH3



13-66
SCH2CH3
CH2OCH2CH3






13-67
SCH2CH3


embedded image








13-68
SCH2CH3
CH2OCH2CF3



13-69
SCH2CH3
CH2SCH3



13-70
SCH2CH3
CH2SCH2CH3






13-71
SCH2CH3


embedded image








13-72
SCH2CH3
CH2SCH2CF3



13-73
SCH2CH3
CH2SOCH3



13-74
SCH2CH3
CH2SOCH2CH3






13-75
SCH2CH3


embedded image








13-76
SCH2CH3
CH2SOCH2CF3



13-77
SCH2CH3
CH2SO2CH3



13-78
SCH2CH3
CH2SO2CH2CH3






13-79
SCH2CH3


embedded image








13-80
SCH2CH3
CH2SO2CH2CF3







text missing or illegible when filed


















TABLE 143








physical





property





(melting


compound


point-


number
R4
R1
ND)







13-81
SCH2CH3
CH2O(CH2)2OCH3



13-82
SCH2CH3
CH2O(CH2)2OCH2CH3



13-83
SCH2CH3
CH2O(CH2)2OCH2CF3



13-84
SCH2CH3
CH2O(CH2)2SCH3



13-85
SCH2CH3
CH2O(CH2)2SCH2CF3



13-86
SCH2CH3
CH2O(CH2)2SOCH3



13-87
SCH2CH3
CH2O(CH2)2SOCH2CF3



13-88
SCH2CH3
CH2O(CH2)2SO2CH3



13-89
SCH2CH3
CH2O(CH2)2SO2CH2CF3






13-90
SCH2CH3


embedded image








13-91
SCH2CH3


embedded image








13-92
SCH2CH3
CH2O(CH2)2NHSO2CH3



13-93
SCH2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



13-94
S(CH2)2CH3
CH3



13-95
S(CH2)2CH3
CF3



13-96
S(CH2)2CH3
CH2OCH3



13-97
S(CH2)2CH3
CH2OCH2CH3






13-98
S(CH2)2CH3


embedded image








13-99
S(CH2)2CH3
CH2OCH2CF3



13-100
S(CH2)2CH3
CH2SCH3



13-101
S(CH2)2CH3
CH2SCH2CH3






13-102
S(CH2)2CH3


embedded image








13-103
S(CH2)2CH3
CH2SCH2CF3



13-104
S(CH2)2CH3
CH2SOCH3



13-105
S(CH2)2CH3
CH2SOCH2CH3






13-106
S(CH2)2CH3


embedded image








13-107
S(CH2)2CH3
CH2SOCH2CF3



13-108
S(CH2)2CH3
CH2SO2CH3



13-109
S(CH2)2CH3
CH2SO2CH2CH3






13-110
S(CH2)2CH3


embedded image








13-111
S(CH2)2CH3
CH2SO2CH2CF3



13-112
S(CH2)2CH3
CH2O(CH2)2OCH3



13-113
S(CH2)2CH3
CH2O(CH2)2OCH2CH3



13-114
S(CH2)2CH3
CH2O(CH2)2OCH2CF3



13-115
S(CH2)2CH3
CH2O(CH2)2SCH3



13-116
S(CH2)2CH3
CH2O(CH2)2SCH2CF3



13-117
S(CH2)2CH3
CH2O(CH2)2SOCH3



13-118
S(CH2)2CH3
CH2O(CH2)2SOCH2CF3



13-119
S(CH2)2CH3
CH2O(CH2)2SO2CH3



13-120
S(CH2)2CH3
CH2O(CH2)2SO2CH2CF3



















TABLE 144








physical





property


com-


(melting


pound


point-


number
Rtext missing or illegible when filed
Rtext missing or illegible when filed
ND)







12-121
S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed


embedded image








12-122
S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed


embedded image








12-123
S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed
CH2O(CH3)2NHSO2CH3



12-124
S(CHtext missing or illegible when filed )text missing or illegible when filed CHtext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )(SO2CH3)



12-125
SCtext missing or illegible when filed Htext missing or illegible when filed
CH3



12-126
SCtext missing or illegible when filed Htext missing or illegible when filed
CF3



12-127
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2OCH3



12-128
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2OCH2CH3






12-129
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-130
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCH2CF3



12-131
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SCH3



12-132
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SCH2CH3






12-133
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-134
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SCHtext missing or illegible when filed CF3



12-135
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH3



12-136
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SOCH2CH3






12-137
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-138
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCH2CF3



12-139
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH3



12-140
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SO2CH2CH3






12-141
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-142
SCtext missing or illegible when filed Htext missing or illegible when filed
CH2SO2CH2CF3



12-143
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH3



12-144
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CH3



12-145
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCH2CF3



12-146
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(text missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed



12-147
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CF3



12-148
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCH3



12-149
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CF3



12-150
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CH3



12-151
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SO2CHtext missing or illegible when filed CF3






12-152
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-153
SCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








12-154
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CH3



12-155
SCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filedtext missing or illegible when filed (SO2CH3)



12-156
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH3



12-157
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CF3



12-158
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCH3



12-159
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CH2OCH2CH3






12-160
SCHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 145








physical





property


compound


(melting point-


number
R4
R1
ND)







13-161
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2OCH3CFtext missing or illegible when filed



13-162
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CH2SCH2



13-163
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCH2CHtext missing or illegible when filed






13-164
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








13-165
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCH2CFtext missing or illegible when filed



13-166
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



13-167
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCH2CHtext missing or illegible when filed






13-168
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








13-169
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCH2CFtext missing or illegible when filed



13-170
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



13-171
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed






13-172
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








13-173
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed



13-174
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed



13-175
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed



13-176
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



13-177
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed



13-178
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



13-179
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed



13-180
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



13-181
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



13-182
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed






13-183
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








13-184
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








13-185
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHtext missing or illegible when filed



13-186
SCH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CHtext missing or illegible when filed )(SOtext missing or illegible when filed CHtext missing or illegible when filed )



13-187
1H-pyrazole-1-yl
CHtext missing or illegible when filed



13-188
1H-pyrazole-1-yl
CFtext missing or illegible when filed



13-189
1H-pyrazole-1-yl
CHtext missing or illegible when filed OCH2



13-190
1H-pyrazole-1-yl
CHtext missing or illegible when filed OCH2CHtext missing or illegible when filed






13-191
1H-pyrazole-1-yl


embedded image








13-192
1H-pyrazole-1-yl


embedded image








13-193
1H-pyrazole-1-yl
CHtext missing or illegible when filed SCH2



13-194
1H-pyrazole-1-yl
CHtext missing or illegible when filed SCH2CHtext missing or illegible when filed






13-195
1H-pyrazole-1-yl


embedded image








13-196
1H-pyrazole-1-yl
CHtext missing or illegible when filed SCH2CFtext missing or illegible when filed



13-197
1H-pyrazole-1-yl
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



13-198
1H-pyrazole-1-yl
CHtext missing or illegible when filed SOCH2CHtext missing or illegible when filed






13-199
1H-pyrazole-1-yl


embedded image








13-200
1H-pyrazole-1-yl
CHtext missing or illegible when filed SOCH2CFtext missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 161








physical





property


compound



text missing or illegible when filed



number
R13
R1

text missing or illegible when filed








 4-441
CH2COCH3
CH2SCH3



 4-442
CH2COCH3
CH2SCH2CH3






 4-443
CH2COCH3


embedded image








 4-444
CH2COCH3
CH2SCH2CF3



 4-445
CH2COCH3
CH2SOCH3



 4-446
CH2COCH3
CH2SOCH2CH3






 4-447
CH2COCH3


embedded image








 4-448
CH2COCH3
CH2SOCH2CF3



 4-449
CH2COCH3
CH2SO2CH3



 4-450
CH2COCH3
CH2SO2CH2CH3






 4-451
CH2COCH3


embedded image








 4-452
CH2COCH3
CH2SO2CH2CF3



 4-453
CH2COCH3
CH2O(CH2)2OCH3



 4-454
CH2COCH3
CH2O(CH2)2OCH2CH3



 4-455
CH2COCH3
CH2O(CH2)2OCH2CF3



 4-456
CH2COCH3
CH2O(CH2)2SCH3



 4-457
CH2COCH3
CH2O(CH2)2SCH2CF3



 4-458
CH2COCH3
CH2O(CH2)2SOCH3



 4-459
CH2COCH3
CH2O(CH2)2SOCH2CF3



 4-460
CH2COCH3
CH2O(CH2)2SO2CH3



 4-461
CH2COCH3
CH2O(CH2)2SO2CH2CF3






 4-462
CH2COCH3


embedded image








 4-463
CH2COCH3


embedded image








 4-464
CH2COCH3
CH2O(CH2)2NHSO2CH3



 4-465
CH2COCH3
CH2O(CH2)2N(CH3)(SO2CH3)



14-466
CH2COC6H5
CH3



14-467
CH2COC6H5
CF3



14-468
CH2COC6H5
CH2OCH3



14-469
CH2COC6H5
CH2OCH2CH3






14-470
CH2COC6H5


embedded image








14-471
CH2COC6H5
CH2OCH2CF3



14-472
CH2COC6H5
CH2SCH3



14-473
CH2COC6H5
CH2SCH2CH3






14-474
CH2COC6H5


embedded image








14-475
CH2COC6H5
CH2SCH2CF3



14-476
CH2COC6H5
CH2SOCH3



14-477
CH2COC6H5
CH2SOCH2CH3






14-478
CH2COC6H5


embedded image








14-479
CH2COC6H5
CH2SOCH2CF3



14-480
CH2COC6H5
CH2SO2CH3






text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 162










physical






property



compound


(melting



number
R text missing or illegible when filed
R1
point text missing or illegible when filed )










text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed













TABLE 163









embedded image




















physical






property



compound


(melting



number
R text missing or illegible when filed
R1
point text missing or illegible when filed )








text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image










text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 164










physical






property



compound


(melting



number
R text missing or illegible when filed
R1
point text missing or illegible when filed )










text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed

















TABLE 165









physical






property



compound


(melting



number
R13
R1
point-ND)








15-81
(CH2)2CH3
CH2O(CH2)2OCH3




15-82
(CH2)2CH3
CH2O(CH2)2OCH2CH3




15-83
(CH2)2CH3
CH2O(CH2)2OCH2CF3




15-84
(CH2)2CH3
CH2O(CH2)2SCH3




15-85
(CH2)2CH3
CH2O(CH2)2SCH2CF3




15-86
(CH2)2CH3
CH2O(CH2)2SOCH3




15-87
(CH2)2CH3
CH2O(CH2)2SOCH2CF3




15-88
(CH2)2CH3
CH2O(CH2)2SO2CH3




15-89
(CH2)2CH3
CH2O(CH2)2SO2CH2CF3







15-90
(CH2)2CH3


embedded image









15-91
(CH2)2CH3


embedded image









15-92
(CH2)2CH3
CH2O(CH2)2NHSO2CH3




15-93
(CH2)2CH3
CH2O(CH2)2N(CH3)(SO2CH3)




15-94
CH2CH═CH2
CH3




15-95
CH2CH═CH2
CF3




15-96
CH2CH═CH2
CH2OCH3




15-97
CH2CH═CH2
CH2OCH2CH3







15-98
CH2CH═CH2


embedded image









15-99
CH2CH═CH2
CH2OCH2CF3




15-100
CH2CH═CH2
CH2SCH3




15-101
CH2CH═CH2
CH2SCH2CH3







15-102
CH2CH═CH2


embedded image









15-103
CH2CH═CH2
CH2SCH2CF3




15-104
CH2CH═CH2
CH2SOCH3




15-105
CH2CH═CH2
CH2SOCH2CH3







15-106
CH2CH═CH2


embedded image









15-107
CH2CH═CH2
CH2SOCH2CF3




15-108
CH2CH═CH2
CH2SO2CH3




15-109
CH2CH═CH2
CH2SO2CH2CH3







15-110
CH2CH═CH2


embedded image









15-111
CH2CH═CH2
CH2SO2CH2CF3




15-112
CH2CH═CH2
CH2O(CH2)2OCH3




15-113
CH2CH═CH2
CH2O(CH2)2OCH2CH3




15-114
CH2CH═CH2
CH2O(CH2)2OCH2CF3




15-115
CH2CH═CH2
CH2O(CH2)2SCH3




15-116
CH2CH═CH2
CH2O(CH2)2SCH2CF3




15-117
CH2CH═CH2
CH2O(CH2)2SOCH3




15-118
CH2CH═CH2
CH2O(CH2)2SOCH2CF3




15-119
CH2CH═CH2
CH2O(CH2)2SO2CH3




15-120
CH2CH═CH2
CH2O(CH2)2SO2CH2CF3



















TABLE 166








physical





property





(melting


compound


point-


number
R13
R1
ND)







15-121
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-122
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-123
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CH2)2NHSO2CH3



15-124
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CH2)2N(CH2)(SO2CH3



15-125
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed



15-126
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CF3



15-127
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2OCH2



15-128
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2OCH2CHtext missing or illegible when filed






15-129
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-130
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2OCHtext missing or illegible when filed CFtext missing or illegible when filed



15-131
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2SCHtext missing or illegible when filed



15-132
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CH3






15-133
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-134
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2SCH2CFtext missing or illegible when filed



15-135
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2SOCHtext missing or illegible when filed



15-136
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CHtext missing or illegible when filed






15-137
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-138
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



15-139
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2SO2CH3



15-140
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed






15-141
CHtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-142
CHtext missing or illegible when filed CH═CHtext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CH2CFtext missing or illegible when filed



15-143
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed O(CH2)2OCHtext missing or illegible when filed



15-144
CHtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed O(CH2)2OCH2CHtext missing or illegible when filed



15-145
CHtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed (CH2)2OCH2CF3



15-146
CHtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CH2)2SCH3



15-147
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CH2)2SCH2CFtext missing or illegible when filed



15-148
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CH2)text missing or illegible when filed SOCHtext missing or illegible when filed



15-149
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



15-150
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



15-151
CH2CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed






15-152
CHtext missing or illegible when filed CHtext missing or illegible when filed CH2


embedded image








15-153
CHtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-154
CHtext missing or illegible when filed CHtext missing or illegible when filed CH2
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSO2CHtext missing or illegible when filed



15-155
CHtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed
CH2O(CH2)3N(CHtext missing or illegible when filed )(SO3CH2)



15-156
CH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed



15-157
CH2Ctext missing or illegible when filed Htext missing or illegible when filed
CFtext missing or illegible when filed



15-158
CH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed



15-159
CH2Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCH2CH2






15-160
CH2Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 167








physical





property


compound


(melting


number
R13
R1
point-ND)







15-161
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed CF



15-162
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed



15-163
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CHtext missing or illegible when filed






15-164
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








15-165
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



15-166
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



15-167
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed Stext missing or illegible when filed CHtext missing or illegible when filed






15-168
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








15-169
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



15-170
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOOtext missing or illegible when filed CHtext missing or illegible when filed



15-171
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed






15-172
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








15-173
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed



15-174
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed



15-175
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(Ctext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed



15-176
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )OCHtext missing or illegible when filed CFtext missing or illegible when filed



15-177
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed



15-178
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



15-179
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed SOCHtext missing or illegible when filed



15-180
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CH2)2SOCH2CFtext missing or illegible when filed



15-181
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CH2)2SO2CH3



15-182
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CH2)2SO2CHtext missing or illegible when filed CFtext missing or illegible when filed






15-183
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








15-184
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed


embedded image








15-185
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHtext missing or illegible when filed



15-186
CHtext missing or illegible when filed Ctext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed N(CH2)(SO2CHtext missing or illegible when filed )



15-187
SOtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed



15-188
SOtext missing or illegible when filed CHtext missing or illegible when filed
CFtext missing or illegible when filed



15-189
SOtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed



15-190
SOtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed






15-191
SOtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-192
SOtext missing or illegible when filed CHtext missing or illegible when filed
CH2OCH2CFtext missing or illegible when filed



15-193
SOtext missing or illegible when filed CHtext missing or illegible when filed
CH2SCH2



15-194
SOtext missing or illegible when filed CHtext missing or illegible when filed
CH2SCH2CH3






15-195
SOtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-196
SOtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



15-197
SOtext missing or illegible when filed CHtext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



15-198
SOtext missing or illegible when filed CHtext missing or illegible when filed
CH2SOCHtext missing or illegible when filed CHtext missing or illegible when filed






15-199
SOtext missing or illegible when filed CHtext missing or illegible when filed


embedded image








15-200
SOtext missing or illegible when filed CHtext missing or illegible when filed
CH2SOCH2CFtext missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 168








physical





property


compound


(melting


number
R13
R1
point-ND)







15-201
SO2CH3
CH3SO2CH3



15-202
SO2CH3
CH2SO2CH2CH3






15-203
SO2CH3


embedded image








15-204
SO2CH3
CH2SO2CH2SF3



15-205
SO2CH3
CH2O(CH2)2OCH3



15-206
SO2CH3
CH2O(CH2)2OCH2CH3



15-207
SO2CH3
CH2O(CH2)2OCH2CF3



15-208
SO2CH3
CH2O(CH2)2SCH3



15-209
SO2CH3
CH2O(CH2)2SCH2CF3



15-210
SO2CH3
CH2O(CH2)2SOCH3



15-211
SO2CH3
CH2O(CH2)2SOCH2CF3



15-212
SO2CH3
CH2O(CH2)2SO2CH3



15-213
SO2CH3
CH2O(CH2)2SO2CH3CF3






15-214
SO2CH3


embedded image








15-215
SO2CH3


embedded image








15-216
SO2CH3
CH2O(CH2)2NHSO2CH3



15-217
SO2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



15-218
SO2CH2CH3
CH3



15-219
SO2CH2CH3
CF3



15-220
SO2CH2CH3
CH2OCH3



15-221
SO2CH2CH3
CH2OCH2CH3






15-222
SO2CH2CH3


embedded image








15-223
SO2CH2CH3
CH2OCH3



15-224
SO2CH2CH3
CH2SCH3



15-225
SO2CH2CH3
CH2SCH2CH3






15-226
SO2CH2CH3


embedded image








15-227
SO2CH2CH3
CH2SCH2CF3



15-228
SO2CH2CH3
CH2SOCH3



15-229
SO2CH2CH3
CH2SOCH2CH3






15-230
SO2CH2CH3


embedded image








15-231
SO2CH2CH3
CH2SOCH2CF3



15-232
SO2CH2CH3
CH2SO2CH3



15-233
SO2CH2CH3
CH2SO2CH2CH3






15-234
SO2CH2CH3


embedded image








15-235
SO2CH2CH3
CH2SO2CH2CF3



15-236
SO2CH2CH3
CH2O(CH2)2OCH3



15-237
SO2CH2CH3
CH2O(CH2)2OCH2CH3



15-238
SO2CH2CH3
CH2O(CH2)2OCH2CF3



15-239
SO2CH2CH3
CH2O(CH2)2SCH3



15-240
SO2CH2CH3
CH2O(CH2)2SCH2CF3



















TABLE 169








physical





property


compound


(melting


number
R13
R1
(point-ND)







15-241
SO2CH2CH3
CH2O(CH2)2SOCH3



15-242
SO2CH2CH3
CH2O(CH2)2SOCH2CF3



15-243
SO2CH2CH3
CH2O(CH2)2SO2CH3



15-244
SO2CH2CH3
CH2O(CH2)2SO2CH2CF3






15-245
SO2CH2CH3


embedded image








15-246
SO2CH2CH3


embedded image








15-247
SO2CH2CH3
CH2O(CH2)2NHSO2CH3



15-248
SO2CH2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



15-249
SO2(CH2)2CH3
CH3



15-250
SO2(CH2)2CH3
CF3



15-251
SO2(CH2)2CH3
CH2OCH3



15-252
SO2(CH2)2CH3
CH2OCH2CH3






15-253
SO2(CH2)2CH3


embedded image








15-254
SO2(CH2)2CH3
CH2OCH2CF3



15-255
SO2(CH2)2CH3
CH2SCH3



15-256
SO2(CH2)2CH3
CH2SCH2CH3






15-257
SO2(CH2)2CH3


embedded image








15-258
SO2(CH2)2CH3
CH2SCH2CF3



15-259
SO2(CH2)2CH3
CH2SOCH3



15-260
SO2(CH2)2CH3
CH2SOCH2CH3






15-261
SO2(CH2)2CH3


embedded image








15-262
SO2(CH2)2CH3
CH2SOCH2CF3



15-263
SO2(CH2)2CH3
CH2SO2CH3



15-264
SO2(CH2)2CH3
CH2SO2CH2CH3






15-265
SO2(CH2)2CH3


embedded image








15-266
SO2(CH2)2CH3
CH2SO2CH2CF3



15-267
SO2(CH2)2CH3
CH2O(CH2)2OCH3



15-268
SO2(CH2)2CH3
CH2O(CH2)2OCH2CH3



15-269
SO2(CH2)2CH3
CH2O(CH2)2OCH2CF3



15-270
SO2(CH2)2CH3
CH2O(CH2)2SCH3



15-271
SO2(CH2)2CH3
CH2O(CH2)2SCH2CF3



15-272
SO2(CH2)2CH3
CH2O(CH2)2SOCH3



15-273
SO2(CH2)2CH3
CH2O(CH2)2SOCH2CF3



15-274
SO2(CH2)2CH3
CH2O(CH2)2SO2CH3



15-275
SO2(CH2)2CH3
CH2O(CH2)2SO2CH2CF3






15-276
SO2(CH2)2CH3


embedded image








15-277
SO2(CH2)2CH3


embedded image








15-278
SO2(CH2)2CH3
CH2O(CH2)2NHSO2CH3



15-279
SO2(CH2)2CH3
CH2O(CH2)2N(CH3)(SO2CH3)



15-280
SO2C6H5
CH3





















TABLE 170










physical






property



compound


(melting



number
R text missing or illegible when filed
R1
point text missing or illegible when filed )










text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 171










physical






property



compound


(melting



number
R text missing or illegible when filed
R1
point text missing or illegible when filed )










text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 172










physical






property



compound


(melting



number
R text missing or illegible when filed
R1
point text missing or illegible when filed )










text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image










text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 173










physical






property



compound


(melting



number
R13
R1
point-ND)










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed
















TABLE 174








physical





property


compound


(melting


number
R1text missing or illegible when filed
R1
point-Ntext missing or illegible when filed )







 4-441
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed



 4-442
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CHtext missing or illegible when filed






 4-443
CHtext missing or illegible when filed COCHtext missing or illegible when filed


embedded image








 4-444
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



 4-445
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed



 4-446
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CHtext missing or illegible when filed






 4-447
CHtext missing or illegible when filed COCHtext missing or illegible when filed


embedded image








 4-448
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



 4-449
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



 4-450
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CHtext missing or illegible when filed






 4-451
CHtext missing or illegible when filed COCHtext missing or illegible when filed


embedded image








 4-452
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed



 4-453
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed



 4-454
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CHtext missing or illegible when filed



 4-455
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



 4-456
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed



 4-457
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



 4-458
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed



 4-459
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



 4-460
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed



 4-461
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed CFtext missing or illegible when filed






 4-462
CHtext missing or illegible when filed COCHtext missing or illegible when filed


embedded image








 4-463
CHtext missing or illegible when filed COCHtext missing or illegible when filed


embedded image








 4-464
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed NHSOtext missing or illegible when filed CHtext missing or illegible when filed



 4-465
CHtext missing or illegible when filed COCHtext missing or illegible when filed
CHtext missing or illegible when filed O(CHtext missing or illegible when filed )text missing or illegible when filed Ntext missing or illegible when filed CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed )



1text missing or illegible when filed -466
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CNtext missing or illegible when filed



1text missing or illegible when filed -467
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CFtext missing or illegible when filed



1text missing or illegible when filed -468
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed



1text missing or illegible when filed -469
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed CH






1text missing or illegible when filed -470
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








1text missing or illegible when filed -471
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed OCHtext missing or illegible when filed CFtext missing or illegible when filed



1text missing or illegible when filed -472
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed



1text missing or illegible when filed -473
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CHtext missing or illegible when filed






1text missing or illegible when filed -474
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








1text missing or illegible when filed -475
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SCHtext missing or illegible when filed CFtext missing or illegible when filed



1text missing or illegible when filed -476
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CNtext missing or illegible when filed SOCHtext missing or illegible when filed



1text missing or illegible when filed -477
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CNtext missing or illegible when filed SOCHtext missing or illegible when filed CHtext missing or illegible when filed






1text missing or illegible when filed -478
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed


embedded image








1text missing or illegible when filed -479
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOCHtext missing or illegible when filed CFtext missing or illegible when filed



1text missing or illegible when filed -480
CHtext missing or illegible when filed COCtext missing or illegible when filed Htext missing or illegible when filed
CHtext missing or illegible when filed SOtext missing or illegible when filed CHtext missing or illegible when filed






text missing or illegible when filed indicates data missing or illegible when filed


















TABLE 175










physical






property



compound



text missing or illegible when filed




number
Rtext missing or illegible when filed
R1

text missing or illegible when filed











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed










text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed



embedded image











text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed






text missing or illegible when filed


text missing or illegible when filed


text missing or illegible when filed









text missing or illegible when filed indicates data missing or illegible when filed














TABLE 176







1H NMR (CDCl3, 300 MHz)







1-1
δ 2.02-2.16(2H, m), 2.49(3H, s), 2.45-2.59(2H, m), 2.70-2.91(2H, m),



7.59(1H, d), 7.74(1H, d), 8.09(1H, s), 9.21(1H, s)


1-19
δ 2.01-2.11(2H, m), 2.45(2H, t), 2.80(2H, t), 3.27(3H, s), 4.83(2H, s), 7.55(1H, d),



7.85(1H, d), 8.11(1H, s), 9.21(1H, s)


1-28
δ 1.77-1.94(2H, m), 2.01-2.36(2H, m), 2.62-2.75(2H, m), 3.87(2H, q),



4.64(2H, s), 7.54(1H, d), 7.61(1H, d), 7.99(1H, s), 9.09(1H, s)


1-66
δ 2.02-2.10(2H, m), 2.44(2H, t), 2.79(2H, t), 3.34(3H, s), 3.42-3.45(2H, m), 3.52-



3.55(2H, m), 4.73(2H, s), 7.65(1H, d), 7.79(1H, d), 8.11(1H, s), 9.21(1H, s)


1-115
δ 1.13(3H, d), 1.72-1.86(1H, m), 2.10-2.16(1H, m), 2.39-2.60(2H, m),



2.48(3H, s), 2.79-2.92(2H, m), 7.60(1H, d), 7.75(1H, d), 8.10(1H, s), 9.21(1H, s)


1-142
δ 1.14(3H, d), 1.73-2.68(5H, m), 3.80(2H, q), 4.84(2H, s), 7.67(1H, d),



7.88(1H, d), 8.12(1H, s), 9.19(1H, s)


1-457
δ 1.12(3H, s), 1.19(1H, s), 1.76-1.89(2H, m), 2.38-2.87(2H, m), 2.44(3H, s),



7.54(1H, d), 7.71(1H, d), 8.07(1H, s), 9.19(1H, s)


1-685
δ 1.26(6H, s), 1.36(6H, s), 2.55(3H, s), 7.60(1H, d), 7.78(1H, d), 8.10(1H, s),



9.22(1H, s)


1-712
δ 1.34(12H, s), 3.84(2H, q), 4.91(2H, s), 7.89(1H, d), 7.91(1H, d), 8.14(1H, s),



9.221(1H, s)


1-799
δ 1.72-2.25(6H, m), 2.47(3H, s), 2.99-3.18(2H, m), 7.61(1H, d), 7.73(1H, d),



8.09(1H, s), 9.21(1H, s)


1-826
δ 1.71-2.07(6H, m), 2.90-3.19(2H, m), 4.84(2H, q), 4.84(2H, s), 7.39(1H, d),



7.88(1H, d), 8.11(1H, s), 9.17(1H, s)


1-913
δ 2.40-2.68(2H, m), 2.44(3H, s), 3.33-3.55(2H, m), 6.21-6.22(1H, m), 6.36-



6.93(2H, m), 6.44-6.47(1H, m), 7.61(1H, d), 7.75(1H, d), 8.10(1H, s), 9.21(1H, s)


2-1
δ 2.71(3H, s), 3.73(3H, s), 7.43(1H, s), 7.84(1H, d), 8.00(1H, d), 8.13(1H, s),



9.25(1H, s)


2-28
δ 3.73(3H, s), 3.93(2H, q), 5.01(1H, s), 7.45(1H, s), 7.99(1H, d), 8.10(1H, d),



8.15(1H, s), 9.24(1H, s)


2-229
δ 1.81(3H, s), 2.59(3H, s), 3.6text missing or illegible when filed (3H, s), 7.76(1H, d), 7.84(1H, d), 8.14(1H, s),



9.26(1H, s)


3-115
δ 1.21-1.40(4H, m), 2.60-2.73(1H, m), 2.66(3H, s), 7.82(1H, d), 7.90(1H, d),



8.11(1H, s), 8.22(1H, s), 9.22(1H, s)


3-343
δ 1.16-1.38(7H, m), 2.30-2.39(1H, m), 2.77(3H, s), 4.10-4.17(2H, q),



7.75(1H, d), 7.85(1H, d), 8.11(1H, s), 9.24(1H, s)


4-115
δ 1.26-1.49(4H, m), 2.38-2.46(1H, m), 2.70(3H, s), 7.85(1H, d), 8.05(1H, d),



8.12(1H, s), 9.23(1H, s)


4-142
δ 1.29-1.36(2H, m), 1.43-1.49(2H, m), 2.33-2.41(1H, m), 3.91(2H, q),



5.00(2H, s), 7.99(1H, d), 8.12(1H, d), 8.14(1H, s), 9.19(1H, s)






text missing or illegible when filed indicates data missing or illegible when filed






Biological Test Example
Test Example 1
Herbicide Effect Test Against Field Weed (Soil Spray Treatment Before Germination)

Preparing Preparation of Active Compound


Carrier: DMF 5 parts by weight


Emulsifier: benzyloxy polyglycol ether 1 part by weight


A preparation of active compound is obtained as an emulsion by mixing 1 part by weight of active compound with the above amounts of carrier and emulsifier. A prescribed amount of preparation is diluted with water.


In a greenhouse, seeds of field weeds [livid amaranth (Amaranthus), green bristle grass (Setaria)] were sown on the surface layer of 16 cm2 pots filled with field soil (sandy loam), and covered with soil. Here, one kind of grass was sown for one pot. Immediately after sowing, the prescribed diluted solutions which were prepared according to the above preparation method of the preparation of respective active compounds were sprayed to soil. After 2 weeks from the treatment, the herbicide effect of each of the compounds was examined. In the evaluation of herbicide effect, complete death was evaluated as 100%, and the case of no herbicide effect was evaluated as 0%. When the herbicide effect is 80% or more, such active compounds are evaluated to have practical utility as a herbicide. Results are shown in Table 177.









TABLE 177







Soil spray treatment before germination











Dosage




Compound number
(g ai/ha)
Green bristle grass
Livid amaranth













1-1
500
100
100


2-1
500
100
100


2-229
500
100
100


3-343
500
95
100


4-115
500
100
100









Test Example 2
Herbicide Effect Test Against Field Weed (Foliage Spray Treatment after Germination)

In a greenhouse, to 16 cm2 pots filled with field soil (sandy loam), seedling plants (2nd-3rd leaf stage) of a field weed (Green bristle grass) were transplanted. After 1 day, the prescribed diluted solutions of preparations of respective active compounds, which were prepared according to the above Test example 1, were sprayed from the upside of the plant body. After 2 weeks from the treatment, the herbicide effect of each of the compounds was examined. Evaluation of herbicidal effect was carried out similarly to Test example 1. Results are shown in Table 178.









TABLE 178







Foliage spray treatment after germination











Compound number
Dosage (g ai/ha)
Green bristle grass














1-36
500
100



1-66
500
90



1-115
500
100



1-457
500
100



3-115
500
100









Test Example 3
Selective Herbicide Effect Test to Field Crop (Soil Spray Treatment Before Germination)

In a greenhouse, seeds of field crops [wheat (Triticum), corn (Zea), soy bean (Glycine)] and weeds [barnyardgrass (Echinochloa), southern crabgrass (Digitaria), livid amaranth (Amaranthus), fat hen (Chenopodium)] were sown on the surface layer of 16 cm2 pots filled with field soil (sandy loam), and covered with soil. After 1 day, the prescribed diluted solutions of preparations of respective active compounds, which were prepared according to Test example 1, were sprayed to the soil. After 2 weeks from the treatment, phytotoxicity to crops and herbicide effect of respective compounds were examined. In the evaluation of herbicide effect and phytotoxicity, complete death was evaluated as 100%, and the case of no herbicide effect or no phytotoxicity was evaluated as 0%. When the herbicide effect is 80% or more, such active compounds are evaluated to have practical utility as a herbicide. When phytotoxicity is 20% or less, such active compounds are evaluated to have excellent safety as a herbicide. Results are shown in Table 179.

















TABLE 179





Compound
Dosage




Southern
Livid



number
(g/ha)
Wheat
Corn
Soy bean
Barnyardgrass
crabgrass
amaranth
Fat hen























1-1
320
10
0
20
100
100
80
100


1-28
320
0
5
10
100
100
90
100


1-115
320
0
0
10
100
100
90
100


1-685
80
40
30
10
100
100
90
90


1-799
320
0
5
30
90
100
100
90


1-913
320
0
0
0
100
100
100
90


3-115
320
5
10
20
100
100
90
100


3-343
320
0
0
0
90
100
100
100


4-115
320
20
30
0
100
100
100
100









Test Example 4
Selective Herbicide Effect Test to Field Crop (Foliage Spray Treatment after Germination)

In a greenhouse, respective seeds of weeds (barnyardgrass, southern crabgrass, fat hen, and livid amaranth) and crops (wheat, corn, and soy bean) were sown on the surface layer of pots filled with field soil, and covered with soil. After one day and 10 days (average 2nd leaf stage for weeds) from the sowing and covering the seeds with soil, the prescribed diluted solutions of preparations of respective active compounds, which were prepared according to Test example 1, were uniformly sprayed onto the soil surfaces of respective test pots and the foliage parts of the plant bodies.


After 14 days from the spraying, the degree of herbicide effect was examined. Evaluation of herbicide effect and phytotoxicity were carried out similarly to Test example 3.


Results are shown in Table 180.

















TABLE 180





Compound
Dosage




Southern
Livid



number
(g/ha)
Wheat
Corn
Soy bean
Barnyardgrass
crabgrass
amaranth
Fat hen























1-36
320
0
10
50
100
100
80
90


1-56
320
0
50
50
100
100
80
90


1-56
320
10
50
50
100
100
100
100


1-457
320
20
50
40
100
100
100
100


2-1
80
0
5
50
100
95
100
90


2-229
320
10
50
60
100
100
100
90









Formulation Example
Formulation Example 1
Granule

Water (25 parts) is added to a mixture of compound No. 1-1 (10 parts) of the present invention, bentonite (montmorillonite) (30 parts), talc (58 parts), and lignin sulfonate (2 parts), and the mixture is kneaded well, made into granules of 10-40 mesh with an extrusion granulator, and dried at 40-50° C. to prepare granules.


Formulation Example 2
Granule

Clay mineral grains (95 parts) having particle size distribution of 0.2-2 mm are put into a rotary mixer, and compound No. 1-1 (5 parts) of the present invention is sprayed together with a liquid diluent under revolution, and the grains are uniformly humidified and then dried at 40-50° C. to prepare granules.


Formulation Example 3
Emulsion

Compound No. 1-1 (30 parts) of the present invention, xylene (55 parts), polyoxyethylene alkyl phenyl ether (8 parts), and calcium alkylbenzene sulfonate (7 parts) are mixed and stirred to prepare an emulsion.


Formulation Example 4
Wettable Powder

Compound No. 1-1 (15 parts) of the present invention, a mixture of white carbon (water-containing amorphous silica fine powders) and powder clay (1:5) (80 parts), sodium alkylbenzene sulfonate (2 parts), and sodium alkylnaphthalene sulfonate-formalin polymer (3 parts) are powder-blended to prepare a wettable powder.


Formulation Example 5
Water-Dispersible Granule

Compound No. 1-1 (20 parts) of the present invention, sodium lignin sulfonate (30 parts), bentonite (15 parts), and calcinated diatomaceous earth powder (35 parts) are sufficiently blended, and water is added thereto, and the mixture is extruded and dried through a screen of 0.3 mm to prepare water-dispersible granules.

Claims
  • 1. A triazolylpyridine ketone derivative represented by formula (I)
  • 2. A compound according to claim 1 wherein R1 represents C1-6 alkyl, C3-8 cycloakyl, C3-8 cycloalkyl-C1-2 alkyl, C1-6haloalkyl, C2-6 alkenyl, C2-6 alkyl, C6-12 aryl, C6-12 aryl-C2-6 alkyl, C1-6 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkoxy-C1-4 alkyl, C2-6 alkenyloxy-C1-4 alkyl, C2-6 alkynyloxy-C1-4 alkyl, C1-6 alkylthio-C1-4 alkyl, C1-6 alkylsulfinyl-C1-4 alkyl, C1-6 alkylsulfonyl-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylthio-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkyl, C1-6 haloalkylthio-C1-4 alkyl, C1-6 haloalkylsulfinyl-C1-4 alkyl, C1-6 haloalkylsulfonyl-C1-4 alkyl, C2-6 alkenylthio-C1-4 alkyl, C2-6 alkenylsulfinyl-C1-4 alkyl, C2-6 alkenylsulfonyl-C1-4 alkyl, C2-6 alkynylthio-C1-4 alkyl, C2-6 alkynylsulfinyl-C1-4 alkyl, C2-6 alkynylsulfonyl-C1-4 alkyl, C1-6 alkoxy-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkoxy-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkoxy-C1-4 alkoxy-C1-4 alkyl, C2-6 alkenyloxy-C1-4 alkoxy-C1-4 alkyl, C2-6 alkynyloxy-C1-4 alkoxy-C1-4 alkyl, C1-6 alkylthio-C1-4 alkoxy-C1-4 alkyl, C1-6 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-6 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylthio-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkylthio-C1-4 alkoxy-C1-4 alkyl, C1-6 halo-alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-6 alkenyl-thio-C1-4 alkoxy-C1-4 alkyl, C2-6 alkenylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-6 alkenylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-6 alkynylthio-C1-4 alkoxy-C1-4 alkyl, C2-6 alkynylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-6 alkynylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-5 cyclic ether-O—C1-4 alkyl, C2-5 cyclic ether-C1-4 alkoxy-C1-4 alkyl, C1-6 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C3-8 cycloalkyl-C1-4 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-6 haloalkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylthio, C1-6 alkylsulfinyl, C1-6 alkylsulfonyl, C1-6 alkoxy, C1-6 haloalkoxy, C1-6 alkoxy-C1-4 alkoxy, or NR2R3,R2 and R3 independently represent hydrogen or C1-6 alkyl, andQ represents
  • 3. A compound according to claim 1 wherein R1 represents C1-4 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-C1-2 alkyl, C1-4 haloalkyl, C2-4 alkenyl, C2-4 alkynyl, C6-8 aryl, C6-8 aryl-C1-2 alkyl, C2-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkoxy C1-4 alkyl, C1-4 haloalkoxy-C1-4 alkyl, C2-4 alkenyloxy-C1-4 alkyl, C2-4 alkynyloxy-C1-4 alkyl, C1-4 alkylthio-C1-4 alkyl, C1-4 alkylsulfinyl-C1-4 alkyl, C1-4 alkylsulfonyl-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylthio-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkyl, C1-4 haloalkylthio-C1-4 alkyl, C1-4 haloalkylsulfinyl-C1-4 alkyl, C1-4 haloalkylsulfonyl-C1-4 alkyl, C2-4 alkenylthio-C1-4 alkyl, C2-4 alkenylsulfinyl-C1-4 alkyl, C2-4 alkenylsulfonyl-C1-4 alkyl, C2-4 alkynylthio-C1-4 alkyl, C2-4 alkynylsulfinyl-C1-4 alkyl, C2-4 alkynylsulfonyl-C1-4 alkyl, C1-4 alkoxy-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl C1-4 alkoxy-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkoxy-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenyloxy-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynyloxy-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylthio-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylthio-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylthio-C1-4 alkoxy-C1-4 alkyl, C1-4 halo-alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenyl-thio-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylthio-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 cyclic ether-O—C1-4 alkyl, C2-4 cyclic ether-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylthio, C1-4 alkylsulfinyl, C1-4 alkylsulfonyl, C1-4 alkoxy, C1-4 haloalkoxy, C1-4 alkoxy-C1-4 alkoxy or NR2R3,R2 and R3 respectively represent hydrogen or C1-4 alkyl, andQ represents
  • 4. A compound according to claim 2 wherein R1 represents C1-4 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-C1-2 alkyl, C1-4 haloalkyl, C2-4 alkenyl, C2-4 alkynyl, C6-8 aryl, C6-8 aryl-C1-2 alkyl, C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkoxy-C1-4 alkyl, C2-4 alkenyloxy-C1-4 alkyl, C2-4 alkynyloxy-C1-4 alkyl, C1-4 alkylthio-C1-4 alkyl, C1-4 alkylsulfinyl-C1-4 alkyl, C1-4 alkylsulfonyl-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylthio-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkyl, C1-4 haloalkylthio-C1-4 alkyl, C1-4 haloalkylsulfinyl-C1-4 alkyl, C1-4 haloalkylsulfonyl-C1-4 alkyl, C2-4 alkenylthio-C1-4 alkyl, C2-4 alkenylsulfinyl-C1-4 alkyl, C2-4 alkenylsulfonyl-C1-4 alkyl, C2-4 alkynylthio-C1-4 alkyl, C2-4 alkynylsulfinyl-C1-4 alkyl, C2-4 alkynylsulfonyl-C1-4 alkyl, C1-4 alkoxy-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkoxy-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkoxy-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenyloxy-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynyloxy-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylthio-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylthio-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylthio-C1-4 alkoxy-C1-4 alkyl, C1-4 halo-alkylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenyl-thio-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkenylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylthio-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylsulfinyl-C1-4 alkoxy-C1-4 alkyl, C2-4 alkynylsulfonyl-C1-4 alkoxy-C1-4 alkyl, C2-4 cyclic ether-O—C1-4 alkyl, C2-4 cyclic ether-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C3-7 cycloalkyl-C1-4 alkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-4 haloalkylsulfonylamino-C1-4 alkoxy-C1-4 alkyl, C1-4 alkylthio, C1-4 alkylsulfinyl, C1-4 alkylsulfonyl, C1-4 alkoxy, C1-4 haloalkoxy, C1-4 alkoxy-C1-4 alkoxy or NR2R3,R2 and R3 independently represent hydrogen or C1-4 alkyl, andQ represents
  • 5. A composition for controlling a weed comprising at least one compound of the formula (I) according to claim 1 and an extender.
  • 6. A composition according to claim 5 further comprising a surfactant.
  • 7. A composition according to claim 5 further comprising an additional herbicide and/or a phytotoxicity-reducing agent.
  • 8. A method of controlling a weed comprising applying at least one compound of formula (I) according to claim 1 to the weed and/or soil around the weed.
  • 9. A compound of formula (I) according to claim 1 wherein R1 represents methyl, andQ represents
  • 10. A compound of formula (I) according to claim 1 wherein R1 represents alkyl.
  • 11. A compound according to claim 1, wherein the compound is
Priority Claims (1)
Number Date Country Kind
2007-202808 Aug 2007 JP national
CROSS REFERENCE TO RELATED APPLICATIONS

This application is a Divisional application of U.S. application Ser. No. 12/671,728, filed May 27, 2010, which is a §371 National Stage Application of PCT/EP2008/0006063, filed Jul. 24, 2008, which claims priority to Japanese Application No. 2007-202808, filed Aug. 3, 2007, the content of all of which are incorporated herein by reference in their entireties.

Divisions (1)
Number Date Country
Parent 12671728 May 2010 US
Child 13900478 US