Heteroaryl and benzyl amide compounds

Abstract

Compounds of formula I

Description

Claims

1. A compound of formula I

2. The compound according to claim 1 wherein R1 is C1-C6alkyl, halo-C1-C6alkyl, C3-C8cycloalkyl, halo-C3-C8cycloalkyl or tri-C1-C6alkylsilyl.

3. The compound according to claim 1 wherein R2 is a group (a).

4. The compound according to claim 1 wherein R2 is a group (b).

5. The compound according to claim 1 wherein R1 is C1-C6alkyl, halo-C1-C6alkyl, halo-C1-C6alkoxy, C3-C8cycloalkyl, halo-C3-C8cycloalkyl or tri-C1-C6alkylsilyl;R2 is hydrogen or a group

6. The compound according to claim 1 wherein R1 is C1-C6alkyl, halo-C1-C6alkyl, halo-C1-C6alkoxy, C3-C8cycloalkyl, halo-C3-C8cycloalkyl or tri-C1-C6alkylsilyl;R2 is hydrogen or a group

7. The compound according to claim 1 wherein R1 is C1-C6alkyl, halo-C1-C6alkyl, halo-C1-C6alkoxy, C3-C8cycloalkyl, halo-C3-C8cycloalkyl or tri-C1-C6alkylsilyl;R2 is hydrogen or a group

8. The compound according to claim 1 wherein R1 is C1-C6alkyl;R2 is a group

9. A process for the production of a compound of formula I according to claim 1 which process comprises reacting an acid derivative, a compound of formula II

10. The compound of claim 5 wherein R2 is

11. The compound of claim 5 wherein R2 is

12. The compound of claim 6 wherein R2 is

13. The compound of claim 6 wherein R2 is

14. The compound of claim 7 wherein R2 is

15. The compound of claim 7 wherein R2 is

16. A pharmaceutical composition comprising a compound according to claim 1 and a pharmaceutically acceptable carrier or adjuvant or mixture thereof.