Heterocyclic acyl sulfonamides

BACKGROUND OF THE INVENTION
This invention relates to heterocyclic or carbonyl sulfonamides which are especially useful as agricultural chemicals.
J. Med. Chem., 1974, 17, 645 describes the synthesis of ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate. No herbicidal use for the compound is disclosed.
Yasuo Nakisumi in Chem. and Pharm. Bulletin, 10 (1962), 612 describes the synthesis of 5,7-dimethylpyrazolo[1,5-A]pyrimidine-3-carboxylic acid.
EP-A-150,974, published 8/7/85, teaches compounds of the following formula to have herbicidal activity. ##STR1##
South African Patent Application 84/8844, discloses substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides of the following formula as herbicides and plant growth regulants. ##STR2##
SUMMARY OF THE INVENTION
This invention relates to novel compounds of Formulae Ia and Ib, agriculturally suitable compositions containing them and their method-of-use as preemergent and/or postemergent herbicides or plant growth regulants ##STR3## wherein R is H; C.sub.1 -C.sub.3 alkyl optionally substituted with halogen; C.sub.1 -C.sub.3 thioalkyl optionally substituted with halogen; benzyl optionally substituted with F, Cl, OCH.sub.3, SCH.sub.3 or NO.sub.2 ; allyl; propargyl; --C(O)(C.sub.1 -C.sub.3 alkyl); CO.sub.2 CH.sub.3 ; or CO.sub.2 CH.sub.2 CH.sub.3 ;
G is Cl, OR' or SR';
R' is C.sub.1 -C.sub.3 alkyl optionally substituted with halogen;
W is O, S, NR" or NOR";
R" is H or C.sub.1 -C.sub.3 alkyl optionally substituted with halogen;
L is ##STR4## R.sub.1 is H; halogen; NO.sub.2 ; CN; C.sub.1 -C.sub.4 alkyl optionally substituted with F, Cl, Br, CN, OCH.sub.3 or SCH.sub.3 ; C.sub.2 -C.sub.4 alkenyl optionally substituted with F, Cl, Br, OCH.sub.3 or SMe; C.sub.3 -C.sub.4 alkynyl; C.sub.3 -C.sub.5 cycloalkyl optionally substituted with F, Cl or CH.sub.3 ; C(O)R.sub.16 ; C(OCH.sub.2 CH.sub.2 O)R.sub.16 ; C(R.sub.16)(OR.sub.17)(OR.sub.18); CO.sub.2 R.sub.19 ; C(O)NR.sub.20 R.sub.21 ; N.sub.3 ; S(O).sub.2 NR.sub.22 R.sub.23 ; S(O).sub.2 OR.sub.24 ; OS(O).sub.2 R.sub.25 ; phenyl optionally substituted by F, Cl, Br, CH.sub.3 or OCH.sub.3 ; ER.sub.26 ; (CH.sub.2).sub.n Q or (CH.sub.2).sub.n Q.sub.1 ;
R.sub.2 is H, halogen, CN, NO.sub.2, C.sub.1 -C.sub.3 alkyl optionally substituted with halogen, CO.sub.2 R.sub.19, S(O).sub.2 NR.sub.27 R.sub.28, NR.sub.29 R.sub.30, ER.sub.31 ; or C.sub.1 -C.sub.2 alkyl substituted with C.sub.1 -C.sub.2 alkoxy, C.sub.1 -C.sub.2 haloalkoxy, C.sub.1 -C.sub.2 alkylthio, C.sub.1 -C.sub.2 haloalkylthio, CN, OH or SH;
R.sub.2 ' is independently H, F, Cl, Br, CH.sub.3, OCH.sub.3, or SCH.sub.3 ;
R.sub.3 is H, CH.sub.3, OCH.sub.3, OCF.sub.2 H, F, Cl, Br, CO.sub.2 R.sub.19, S(O).sub.2 N(CH.sub.3).sub.2, OS(O).sub.2 CH.sub.3 or S(O).sub.p CH.sub.3 ;
R.sub.4 is Cl, NO.sub.2, CO.sub.2 CH.sub.3, CO.sub.2 CH.sub.2 CH.sub.3, C(O)N(CH.sub.3).sub.2, OS(O).sub.2 CH.sub.3, S(O).sub.2 CH.sub.3, S(O).sub.2 CH.sub.2 CH.sub.3, OCH.sub.3 or OCH.sub.2 CH.sub.3 ;
R.sub.5 is H, C.sub.1 -C.sub.3 alkyl, F, Cl, Br, NO.sub.2, S(O).sub.2 NR.sub.32 R.sub.33, S(O).sub.2 N(OCH.sub.3)CH.sub.3 or S(O).sub.p R.sub.34 ;
R.sub.6 is C.sub.1 -C.sub.3 alkyl or phenyl;
R.sub.7 is H, C.sub.1 -C.sub.3 alkyl optionally substituted with halogen, C.sub.3 -C.sub.4 alkenyl, or phenyl;
R.sub.8 is H or CH.sub.3 ;
R.sub.9 is H, CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.10 is H, CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.11 is H, Cl or C.sub.1 -C.sub.3 alkyl;
R.sub.12 is H, C.sub.1 -C.sub.4 alkyl optionally substituted with F, Cl, Br or OCH.sub.3 ; C.sub.3 -C.sub.5 cycloalkyl optionally substituted with F, Cl or OCH.sub.3 ; C.sub.3 -C.sub.4 alkenyl; or C.sub.3 -C.sub.4 alkynyl;
R.sub.13 is H or C.sub.1 -C.sub.3 alkyl;
R.sub.14 is H, F, Cl, Br, CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.15 is H, F, Cl, Br, CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.16 is C.sub.1 -C.sub.4 alkyl optionally substituted with F, Cl, Br or OCH.sub.3 ; C.sub.3 -C.sub.5 cycloalkyl optionally substituted with F or Cl; or C.sub.3 -C.sub.4 alkenyl;
R.sub.17 and R.sub.18 are independently C.sub.1 -C.sub.3 alkyl;
R.sub.19 is C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.4 alkenyl, C.sub.3 -C.sub.4 alkynyl; C.sub.2 -C.sub.4 haloalkyl, C.sub.2 -C.sub.3 cyanoalkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.4 -C.sub.7 cycloalkylalkyl or C.sub.2 -C.sub.4 alkoxyalkyl;
R.sub.20 is H, CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.21 is CH.sub.3, CH.sub.2 CH.sub.3, CH.sub.2 CH.sub.2 CH.sub.3, OCH.sub.3 or OCH.sub.2 CH.sub.3 ; or R.sub.20 and R.sub.21 may be taken together to form --(CH.sub.2).sub.2 (CH.sub.2).sub.n (CH.sub.2).sub.2 -- and --CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 --;
R.sub.22 is C.sub.1 -C.sub.4 alkyl, C.sub.2 -C.sub.3 cyanoalkyl, OCH.sub.3, OCH.sub.2 CH.sub.3, N(CH.sub.3).sub.2, C.sub.3 -C.sub.4 alkenyl, C.sub.3 -C.sub.4 alkynyl, cyclopropylmethyl or C.sub.3 -C.sub.4 cycloalkyl;
R.sub.23 is H, C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.4 alkenyl; or
R.sub.22 and R.sub.23 may be taken together as --(CH.sub.2).sub.3 --, --(CH.sub.2).sub.4 -- or --CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 --;
R.sub.24 is C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 haloalkyl;
R.sub.25 is C.sub.1 -C.sub.3 alkyl or N(CH.sub.3).sub.2 ;
R.sub.26 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.2 -C.sub.4 alkoxyalkyl, C.sub.3 -C.sub.4 alkenyl, C.sub.3 -C.sub.4 alkynyl, phenyl optionally substituted by F, Cl, Br, CH.sub.3 or OCH.sub.3, or C.sub.2 -C.sub.4 haloalkenyl;
R.sub.27 is C.sub.1 -C.sub.3 alkyl;
R.sub.28 is H, C.sub.1 -C.sub.4 alkyl or methoxy;
R.sub.27 and R.sub.28 may be taken together to form --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.5 -- or --CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 --;
R.sub.29 and R.sub.30 are independently H, CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.31 is C.sub.1 -C.sub.4 alkyl optionally substituted with F, Cl or OCH.sub.3 ;
R.sub.32 is CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.33 is H, CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.34 is C.sub.1 -C.sub.3 alkyl, C.sub.3 -C.sub.4 alkenyl or C.sub.3 -C.sub.4 alkynyl;
Q.sub.a is O, S, S(O), S(O).sub.2 or NCH.sub.3 ;
Q.sub.b is O, S or S(O).sub.2 ;
Q.sub.c is O, S, NH, N(C.sub.1 -C.sub.3 alkyl), NCH.sub.2 CH.dbd.CH.sub.2 or NCH.sub.2 C.tbd.CH;
Q.sub.d is O, NH, N(C.sub.1 -C.sub.3 alkyl), NCH.sub.2 CH.dbd.CH.sub.2 or NCH.sub.2 C.tbd.CH;
Q.sub.e is O or NR.sub.12 ;
Q.sub.f is C(O) or S(O).sub.2 ;
Q.sub.g is O, S, NH or N(C.sub.1 -C.sub.3 alkyl);
n is 0 or 1;
p is 0, 1 or 2;
W' is O or S;
E is O, S, S(O) or S(O).sub.2 ;
Q is ##STR5## wherein Q.sub.1 -1 through Q.sub.1 -87 may be optionally substituted with 1 or 2 groups selected from C.sub.1 -C.sub.2 alkyl or C.sub.1 -C.sub.2 haloalkyl;
R.sub.35 is H, C.sub.1 -C.sub.3 alkyl or allyl;
R.sub.36 and R.sub.37 are independently H or C.sub.1 -C.sub.3 alkyl;
X.sub.b is O or NR.sub.36 ; and
X.sub.c is O, S, S(O), S(O).sub.2 or NR.sub.36 ;
A is ##STR6## X or Y is H, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, C.sub.2 -C.sub.5 alkoxyalkyl, C.sub.2 -C.sub.5 alkoxyalkoxy, amino, C.sub.1 -C.sub.3 alkylamino, di(C.sub.1 -C.sub.3 alkyl)amino, C.sub.3 -C.sub.4 alkenyloxy, C.sub.3 -C.sub.4 alkynyloxy, C.sub.2 -C.sub.5 alkylsulfinylalkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.2 -C.sub.5 alkylsulfonylalkyl, C.sub.3 -C.sub.5 cycloalkyl, C.sub.2 -C.sub.4 alkynyl, C.sub.2 -C.sub.5 alkylthioalkyl, ##STR7## or N(OCH.sub.3)CH.sub.3 ; W.sub.1 and W.sub.2 are independently O or S;
m and m' are independently 2 or 3;
R.sub.a is H or CH.sub.3 ;
R.sub.b and R.sub.c are independently C.sub.1 -C.sub.2 alkyl;
Z is CH, N, CCH.sub.3, CCH.sub.2 CH.sub.3, CCl or CBr;
Z.sub.1 is C--U, N or N--O;
Z.sub.2 and Z.sub.3 are independently N or C--U;
Z.sub.4 is NCH.sub.3, O, S or CH.sub.2 ;
U is H, F, Cl, Br, C.sub.1 -C.sub.2 alkyl optionally substituted by F, Cl, Br or OCH.sub.3, CN, NO.sub.2, NMe.sub.2, OR'", SR'" or CO.sub.2 CH.sub.3 ;
R'" is C.sub.1 -C.sub.2 alkyl optionally substituted with F, Cl, Br or OCH.sub.3 ;
X.sub.a is CH.sub.3, CH.sub.2 C.sub.3 or CH.sub.2 CF.sub.3 ; and
X.sub.d is H or CH.sub.3 ;
and their agriculturally suitable salts; provided that
(1) the total number of carbon atoms of R.sub.22 and R.sub.23 is less than or equal to five;
(2) when X or Y is Cl, F, Br or I, then Z is CH and the remaining X or Y is OCH.sub.3, OCH.sub.2 CH.sub.3, N(OCH.sub.3)CH.sub.3, NHCH.sub.3, N(CH.sub.3).sub.2 or OCF.sub.2 H;
(3) when X or Y is C.sub.1 haloalkoxy, then Z is CH;
(4) at least one of X or Y is X' where X' is H, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, C.sub.2 -C.sub.5 alkoxyalkoxy, amino, C.sub.1 -C.sub.3 alkylamino or di(C.sub.1 -C.sub.3 alkyl)amino; and
(5) the total number of carbon atoms of R.sub.27 and R.sub.28 is less than or equal to five.
In the above definitions, the term "alkyl", used either alone or in compound words such as "alkylthio" or "haloalkyl", denotes straight chain or branched alkyl, e.g. methyl, ethyl, n-propyl, isopropyl or the different butyl isomers.
Alkoxy denotes methoxy, ethoxy, n-propyloxy, isopropyloxy and the different butyl isomers.
Alkenyl denotes straight chain or branched alkenes, e.g. 1-propenyl, 2-propenyl, 3-propenyl and the different butenyl isomers.
Alkynyl denotes straight chain or branched alkynes, e.g. ethynyl, 1-propynyl, 2-propynyl and the different butynyl isomers.
Alkylsulfonyl denotes methylsulfonyl, ethylsulfonyl and the different propylsulfonyl isomers.
Alkylthio, alkylsulfinyl, alkylamino, etc. are defined analogously to the above examples.
Cycloalkyl denotes cyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl.
The term "halogen", either alone or in compound words such as "haloalkyl", denotes fluorine, chlorine, bromine or iodine. Further, when used in compound words such as "haloalkyl" said alkyl may be partially halogenated or fully substituted with halogen atoms and said halogen atoms may be the same or different. Examples of haloalkyl include CH.sub.2 CH.sub.2 F, CF.sub.2 CF.sub.3 and CH.sub.2 CHFCl.
The total number of carbon atoms in a substituent group is indicated by the C.sub.i -C.sub.j prefix where i and j are numbers from 1 to 7. For example, C.sub.1 -C.sub.3 alkylsulfonyl would designate methylsulfonyl through propylsulfonyl, C.sub.2 alkoxyalkoxy would designate OCH.sub.2 OCH.sub.3, C.sub.2 cyanoalkyl would designate CH.sub.2 CN and C.sub.3 cyanoalkyl would designate CH.sub.2 CH.sub.2 CN and CH(CN)CH.sub.3.
Preferred Compounds
Preferred for reasons of increased ease of synthesis and/or greater herbicidal efficacy are:
1. Compounds of Formula I where A is A-1, A-2, A-4, A-6, A-7, A-8, A-9, A-11, A-16 or A-19.
2. Compounds of Preferred 1 where
Formula I is Formula Ia;
W is O; and
R is H.
3. Compounds of Preferred 1 where
Formula I is Formula Ib;
G is OR' or SR'.
4. Compounds of Preferred 2 where
R.sub.2 ' is H;
X' is C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, OCF.sub.2 H, CH.sub.2 F, CF.sub.3, OCH.sub.2 CH.sub.2 F, OCH.sub.2 CHF.sub.2, OCH.sub.2 CF.sub.3, CH.sub.2 Cl or CH.sub.2 Br;
X or Y is H, C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, CH.sub.2 OCH.sub.3, Cl, F, Br, I, CH.sub.2 OCH.sub.2 CH.sub.3, NHCH.sub.3, N(OCH.sub.3)CH.sub.3, N(CH.sub.3).sub.2, CF.sub.3, SCH.sub.3, OCH.sub.2 CH.dbd.CH.sub.2, OCH.sub.2 C.tbd.CH, OCH.sub.2 CH.sub.2 OCH.sub.3, CH.sub.2 SCH.sub.3, ##STR8## OCF.sub.2 H, SCF.sub.2 H, cyclopropyl, C.tbd.CH or C.tbd.CCH.sub.3 ; and Z is CH.
5. Compounds of Preferred 4 where
R.sub.1 is halogen; NO.sub.2 ; CN; C.sub.1 -C.sub.3 alkyl optionally substituted with F, CL, Br, CN, OCH.sub.3 or SCH.sub.3 ; C.sub.3 alkenyl optionally substituted with F, Cl or Br; C.sub.3 alkynyl; C.sub.3 cycloalkyl optionally substituted with F, Cl or CH.sub.3 ; C(O)R.sub.16 ; C(OCH.sub.2 CH.sub.2 O)R.sub.16 ; C(R.sub.16)(OR.sub.17)(OR.sub.18); CO.sub.2 R.sub.19 ; C(O)NR.sub.20 R.sub.21 ; N.sub.3 ; S(O).sub.2 NR.sub.22 R.sub.23 ; OS(O).sub.2 R.sub.25 ; ER.sub.25 ; (CH.sub.2).sub.n Q or (CH.sub.2).sub.n Q.sub.1 ;
R.sub.16 is C.sub.1 -C.sub.3 alkyl, C.sub.3 cycloalkyl or C.sub.3 alkenyl;
R.sub.17 and R.sub.18 are C.sub.1 -C.sub.2 alkyl;
R.sub.19 is C.sub.1 -C.sub.3 alkyl, C.sub.3 alkenyl, CH.sub.2 CH.sub.2 F, CH.sub.2 CH.sub.2 Cl, CH.sub.2 CH.sub.2 OCH.sub.3 or cyclopropyl methyl;
R.sub.20 is H or CH.sub.3 ;
R.sub.21 is CH.sub.3, CH.sub.2 CH.sub.3 or OCH.sub.3 ;
R.sub.22 is C.sub.1 -C.sub.3 alkyl, OCH.sub.3, OCH.sub.2 CH.sub.3, allyl, propargyl or cyclopropyl;
R.sub.23 is H, CH.sub.3 or CH.sub.2 CH.sub.3 ;
R.sub.26 is C.sub.1 -C.sub.3 alkyl optionally substituted by halogen, C.sub.2 -C.sub.3 alkoxyalkyl, allyl, propargyl or C.sub.2 -C.sub.3 haloalkenyl;
n is 0; and
Q.sub.1 is Q.sub.1 -1, Q.sub.1 -4, Q.sub.1 -5, Q.sub.1 -7, Q.sub.1 -10, Q.sub.1 -11, Q.sub.1 -12, Q.sub.1 -17, Q.sub.1 -19, Q.sub.1 -20, Q.sub.1 -24, Q.sub.1 -25, Q.sub.1 -27, Q.sub.1 -28, Q.sub.1 -36, Q.sub.1 -38, Q.sub.1 -46, Q.sub.1 -47, Q.sub.1 -54, Q.sub.1 -56, Q.sub.1 -59, Q.sub.1 -60, Q.sub.1 -63, Q.sub.1 -71, Q.sub.1 -74, Q.sub.1 -76, Q.sub.1 -78 or Q.sub.1 -79.
6. Compounds of Preferred 5 where
R.sub.2 is H; halogen; CN; NO.sub.2 ; CH.sub.3 ; CF.sub.3 ; ER.sub.31 ; or C.sub.1 -C.sub.2 alkyl substituted with C.sub.1 -C.sub.2 alkoxy, C.sub.1 -C.sub.2 haloalkoxy, C.sub.1 -C.sub.2 alkylthio, C.sub.1 -C.sub.2 haloalkylthio or CN;
E is O or S; and
R.sub.31 is C.sub.1 -C.sub.2 alkyl optionally substituted with F, Cl or OCH.sub.3.
7. Compounds of Preferred 6 where
W' is O;
Q.sub.e is NR.sub.12 ;
Q.sub.c is O, NH, N(C.sub.1 -C.sub.3 alkyl), NCH.sub.2 CH.dbd.CH.sub.2, or NCH.sub.2 C.tbd.CH;
Q.sub.f is S(O).sub.2 ;
Q.sub.g is O or S;
R.sub.11 is H or CH.sub.3 ; and
R.sub.13 is H or CH.sub.3.
8. Compounds of Preferred 7 where
X' is CH.sub.3, OCH.sub.3, OCH.sub.2 CH.sub.3 or OCF.sub.2 H; and
X or Y is CH.sub.3, OCH.sub.3, C.sub.2 H.sub.5, CH.sub.2 OCH.sub.3, NHCH.sub.3, CH(OCH.sub.3).sub.2, Cl or cyclopropyl.
9. Compounds of Preferred 8 where A is A-1.
10. Compounds of Preferred 8 where A is A-2.
11. Compounds of Preferred 8 where A is A-4.
12. Compounds of Preferred 8 where A is A-6.
13. Compounds of Preferred 8 where A is A-7.
14. Compounds of Preferred 8 where A is A-8.
15. Compounds of Preferred 8 where A is A-9.
16. Compounds of Preferred 8 where A is A-11.
17. Compounds of Preferred 8 where A is A-16.
18. Compounds of Preferred 8 where A is A-19.
19. Compounds of Preferred 8 where
A is A-1;
L is L-1, L-3, L-4, L-5, L-6, L-7, L-8, L-9, L-11, L-12, L-13, L-14, L-15 or L-16;
Z.sub.1 is CH or N; and
Z.sub.2 is CH or N.
20. Compounds of Preferred 19 where Z.sub.1 and Z.sub.2 are N.
21. Compounds of Preferred 8 where
A is A-4;
L is L-1, L-3, L-4, L-5, L-6, L-7, L-8, L-9, L-11, L-12, L-13, L-14, L-15 or L-16;
Z.sub.4 is O or S; and
Z.sub.1 is N, CH or CCH.sub.3.
Specifically Preferred for reasons of greatest ease of synthesis and/or greatest herbicidal efficacy are:
5,7-Dimethyl-N-[[2-(methylsulfonyl)phenyl]sulfonyl]pyrazolo[1,5-A]pyrimidine-3-carboxamide
Methyl 2-[[[(5,7-dimethylpyrazolo[1,5-A]pyrimidin-3-yl)carbonyl]amino]sulfonyl]benzoate
Methyl 2-[[[(5,7-dimethyl[1,2,3]triazolo[1,5-A]pyrimidine-3-yl)carbonyl]amino]sulfonyl]benzoate
N-[[2-(1-Ethyl-1H-tetrazol-5-yl)phenyl]sulfonyl]-5,7-dimethylpyrazolo[1,5A-]pyrimidine-3-carbamate
N-[[2-[(Dimethylamino)sulfonyl]phenyl]sulfonyl]-5,7-dimethyl[1,2,3]triazolo[1,5A-]pyrimidine-3-carboxamide
N-[(2-Chlorophenyl)sulfonyl]-5,7-dimethyl[1,2,3]-triazolo[1,5-A]pyrimidine-3-carboxamide
N-[(2,6-Dibromophenyl)sulfonyl]-5,7-dimethyl-[1,2,3]triazolo[1,5-A]pyrimidine-3-carboxamide
The compounds disclosed can be variously named using alternative rules of nomenclature. In particular, 5,7-dimethyl-N-[[(2-methylsulfonyl)-phenyl]sulfonyl]pyrazolo[1,5-A]pyrimidine-3-carboxamide is alternatively named 5,7-dimethyl-N-((2-(methylsulfonyl)phenylsulfonyl))pyrazolo-((1,5-A))pyrimidine-3-carboxamide. Methyl 2-[[[(5,7-dimethylpyrazolo[1,5-A]pyrimidin-3-yl)-carbonyl]amino]sulfonyl]benzoate is alternatively named 2-(((((5,7-dimethylpyrazolo((1,5-A))-pyrimidine-3-yl)carbonylamino))sulfonyl))benzoic acid, methyl ester. Methyl 2-[[[(5,7-dimethyl[1,2,3]-triazolo[1,5-A]pyrimidin-3-yl)carbonyl]amino]sulfonyl]-benzoate is alternatively named 2-[(((5,7-dimethyl-((1,2,3))triazolo((1,5-A))pyrimidine-3-yl)carbonylamino))sulfonyl]benzoic acid, methyl ester.
N-[[2-(1-ethyl-1H-tetrazol-5-yl)phenyl]sulfonyl]-5,7-dimethylpyrazolo[1,5-A]pyrimidine-3-carbamate is alternatively named N-((2-(1-ethyl-1H-tetrazol-5-yl)phenylsulfonyl))-5,7-dimethylpyrazolo((1,5-A))-pyrimidine-3-carbamate.
DETAILED DESCRIPTION OF THE INVENTION
Synthesis
Compounds of Formula Ia and Formula Ib can be prepared using one or more of the reactions and techniques described in this section. In some cases, substituents on the starting materials may be incompatible with the reaction conditions described. It will be readily apparent to one skilled in the art to use either standard protecting groups (e.g., ketal as a protecting group for ketone) or one of the alternative methods described.
Equation 1 illustrates the reaction of N-sulfonylheterocyclic carboxamides of Formula Ia (W is O) with Lawesson's Reagent of Formula II to give the desired N-sulfonylthiocarboxamides of Formula Ia (W is S).
Equation 1 ##STR9## wherein A, R and L are as previously defined.
The reaction of Equation 1 is best carried out in an inert aprotic solvent such as toluene or xylene at a temperature between about 0.degree. and 145.degree. C. In cases in which the products are insoluble in the reaction solvent, they may be isolated by simple filtration. When the products are soluble, they may be isolated by evaporation of the solvent, followed by crystallization or chromatography of the residue.
Compounds of Formula Ia (W is O and A is not A-3) can be synthesized by the reaction of heterocyclic carboxylic acids or their anion of Formula III with thionyl chloride or oxalyl chloride in the presence of a base such as pyridine, 2,6-lutidine or triethylamine if desired and then by the reaction of the carbonyl chloride of Formula IV which is formed in situ, with a sulfonamide of Formula V in the presence of a base such as pyridine, 2,6-lutidine or triethylamine as shown below in Equation 2.
Equation 2 ##STR10## wherein M is H, Li, K or Na;
R and L are as previously defined; and
A' is A-1, A-2, A-4, A-5, A-6, A-7, A-8, A-9, A-11, A-12, A-13, A-14, A-15, A-16, A-17, A-18 or A-19.
The sequential reactions of Equation 2 are best carried out in an inert aprotic solvent such as methylene chloride or ether. The excess thionyl chloride or oxalyl chloride is evaporated before the carbonyl chloride of Formula IV, is reacted with the sulfonamide of Formula V. The products are readily isolated by evaporation of the solvent, followed by chromatography, or alternatively by extraction of the residue with sodium carbonate aqueous solution, washing the aqueous solution with ether, acidifying the aqueous solution with an inorganic acid such as hydrochloric acid and filtration.
Alternatively, compounds of Formula Ia (W is O, A is not A-3) can be synthesized by the reaction of heterocyclic carboxylic acids of Formula III with 1,1-carbonyldiimidazole of Formula VI and then by the reaction of the carbonylimidazole of Formula VII, which is formed in situ, with a sulfonamide of Formula V in the presence of a base such as pyridine or triethylamine as shown below in Equation 3.
Equation 3 ##STR11## wherein A', R and L are as previously defined.
The reaction of Equation 3 is best carried out in an inert aprotic solvent such as methylene chloride, chloroform or acetonitrile at a temperature between about 0.degree. C. to 82.degree. C. The product can be isolated by evaporation of solvent, adding the residue to water, acidifying the aqueous solution with hydrochloric acid and filtrating. Crystallization or chromatography may be used for further purification. In cases where the crude products are insoluble in the reaction solvent, the products may be isolated by filtrating, adding the crude products collected to water, acidifying the aqueous solution with hydrochloric acid and filtrating. Crystallization or chromatography may also be used for further purification as would be preferred by one skilled in the art.
Compounds of Formula Ia (W is O, A is not A-3) can also be synthesized by the reaction of heterocyclic carboxylic acid of Formula III with 2-chloro-1-methyl pyridinium iodide of Formula VIa in the presence of a base such as triethylamine and then by the reaction of the 2-(heterocyclic carbonyloxy)-1-methylpyridinium salt of Formula VIIa, which is formed in situ, with a sulfonamide of Formula V in the presence of a base such as triethylamine as shown below in Equation 3a.
Equation 3a ##STR12## wherein A', R and L are as previously defined.
The reaction of Equation 3a is best carried out in an inert aprotic solvent such as methylene chloride, chloroform or acetonitrile at a temperature between -30.degree. C. to 82.degree. C. The product can be isolated by evaporation of solvent, adding the residue to water, acidifying the aqueous solution with an acid such as hydrochloric acid and filtration. Crystallization or chromatography may be used for further purification.
Reactions of the heterocycles or their lithium anions of Formula XVII with sulfonyl isocyanates of Formula IX can also afford compounds of Formula Ia (W is O, A is not A-3) as shown below in Equation 3b ##STR13## wherein A' and L are as previously defined
M' is H or Li.
The reaction of Equation 3b is best carried out in an inert aprotic solvent such as tetrahydrofuran or dichloromethane at a temperature between -78.degree. C. and 80.degree. C. The product can be isolated by concentrating the reaction mixture and acidifying (if appropriate) the residue in water followed by filtration. Crystallization or chromatography may be used for further purification.
Compounds of Formula Ia (W is O, A is A-3) can be synthesized by the reaction of compounds of Formula VIII with a sulfonyl isocyanate of Formula IX or a N-phenoxycarbonylsulfonamide of Formula X in the presence of a base such as triethylamine or DBU as shown below in Equation 4.
Equation 4a ##STR14##
Equation 4b ##STR15## wherein X, Y, Z, Z.sub.1, Z.sub.2 and L are as previously defined.
The reaction of Equation 4 is best carried out in an inert aprotic solvent such as acetonitrile, chloroform or methylene chloride at a temperature between about 0.degree. C. to 80.degree. C. In cases where the products are insoluble in the reaction solvents, they can be isolated by simple filtration. Alternatively, the products can be isolated by evaporating the reaction solvents after washing with dilute aqueous acid such as hydrochloric acid, if desired, triturated in a solvent such as ether, n-butylchloride or hexane and then filtrating. The products may be further purified by crystallization or chromatography.
Compounds of Formula Ia (W is S, NR" or NOR"0 and R is H) can be synthesized by the reaction of imidoyl chlorides of Formula Ib (G is Cl) with an amine, hydroxyamine, alkoxyamine or hydrogen sulfide of Formula XI in the presence of a base such as triethylamine if desired as shown below in Equation 5.
Equation 5 ##STR16## wherein W is S, NR" or NOR"; and
A, L and R" are as previously defined.
The reaction of Equation 5 is best carried out in an inert aprotic solvent such as methylene chloride or dichloroethane at a temperature between about 0.degree. C. and 80.degree. C. The products may be isolated by evaporation of the solvent, followed by crystallization or chromatography of the residue.
Compounds of Formula Ia (W is O, NR" or NOR" and R is not H) can be synthesized by contacting compounds of Formula Ia (W is O, NR" or NOR" and R is H) with a base such as n-butyllithium or sodium hydride followed by contacting with an alkylating agent of Formula XII as shown below in Equation 6.
Equation 6 ##STR17## wherein A, R" and L are as previously defined:
R is as previously defined but other than H; and P1 V is Cl, Br or I.
The reaction of Equation 6 is best carried out in an inert aprotic solvent such as ether or tetrahydrofuran at a temperature between about -80.degree. C. to 70.degree. C. The products may be isolated by evaporation of solvent, followed by crystallization or chromatography of the residue.
Equation 7 illustrates the reaction of imidoyl chlorides or Formula Ib (G is Cl) with an alcohol or a mercaptan of Formula XIII in the presence of a base such as triethylamine to give compounds of Formula Ib (G is OR' or SR').
Equation 7 ##STR18## wherein A and L are as previously defined; and
G.sub.1 is OR' or SR'.
The reaction of Equation 7 is best carried out in an inert aprotic solvent such as methylene chloride or dichloroethane at a temperature between about 0.degree. C. and 80.degree. C. The products may be isolated by evaporation of the solvent, followed by crystallization of chromatography of the residue.
The imidoyl chlorides of Formula Ib (G is Cl) can be synthesized by the reaction of carbonyl sulfonamides of Formula Ia (R is H and W is O) with triphenylphosphine/CCl.sub.4 or PCl.sub.5 /POCl.sub.3 as shown below in Equation 8.
Equation 8 ##STR19## wherein A and L are as previously defined.
The reaction of Equation 8 is best carried out in CCl.sub.4 or POCl.sub.3 at a temperature between about 0.degree. C. and 105.degree. C. The products may be isolated by evaporation of the solvent, followed by crystallization or chromatography of the residue as would be apparent to one skilled in the art.
Compounds of Formula Ib (G is SR') may also be prepared by the reaction of N-sulfonylthiocarboxamides of Formula Ia (W is S and R is H), with an alkylating agent of Formula XIV in the presence of a base such as potassium carbonate as shown below in Equation 9.
Equation 9 ##STR20## wherein A, R' and L are as previously defined; and
V is Cl, Br or I.
The reaction of Equation 9 is best carried out in an inert aprotic solvent such as N,N-dimethylformamide at a temperature between about 0.degree. C. and 100.degree. C. The products may be isolated by evaporation of the solvent, followed by crystallization or chromatography of the residue.
The sulfonamides of Formula V, the sulfonyl isocyanates of Formula IX and the N-phenoxycarbonylsulfonamides of Formula X can be prepared by methods known in the art or by obvious modification of these known methods. The anion of heterocyclic carboxylic acid of Formula III (M is K, Li, Na) can be prepared from the acid of Formula III (M is H) by methods known in the art or by modification of these methods.
The heterocyclic carboxylic acid of Formula III (M is H) can be synthesized by the methods shown below in Equations 10, 11, 11a and 12.
Equation 10 illustrates the conversion of the heterocyclic carboxylic acid esters of Formula XV to the acid of Formula III (M is H) by the method taught by Yasuo Makisumi in Chem. Pharm. Bull., 10, 612 (1962) or by modification of this method (e.g., aqueous alcohol instead of water as reaction solvent).
Equation 10 ##STR21## wherein A' is as previously defined; and
R.sub.35 is C.sub.1 -C.sub.5 alkyl or benzyl.
The reaction of Equation 10 is best carried out in an aqueous alcoholic solution or water at a temperature between 0.degree. C. to 100.degree. C. The product can be isolated by concentrating the reaction solution, acidifying it to pH<3 with an acid such as hydrochloric acid followed by filtration. Crystallization or chromatography may be used for further purification.
Alternatively, the heterocyclic acid esters of Formula XV can be converted to the acid of Formula III (M is H) by reaction with acids such as hydrobromic acid or by reaction with trimethylsilyliodide (or boron tribromide) as shown below in Equation 11.
Equation 11 ##STR22## wherein A' and R.sub.35 are as previously defined.
The reaction of Equation 11 is best carried out under the conditions taught by C. S. Marvel, et al. in J. Am. Chem. Soc., 62 3495 (1940), A. M. Felix in J. Org. Chem., 39 (10) 1427 (1974) and M. E. Jung, et al. in J. Am. Chem. Soc., 99 968 (1977).
Equation 11a illustrates the conversion of the heterocyclic acid benzyl esters of Formula XV (R.sub.35 is benzyl) to the acid of Formula III (M is M) by hydrogenation in the presence of a catalyst such as palladium on carbon.
Equation 11a ##STR23##
The reaction of Equation 11a is best carried out in an inert solvent such as methanol, ethanol or ethylacetate at a temperature between 0.degree. C.-80.degree. C. The product can be isolated by filtering the reaction solution and concentrating the filtrate. Crystallization or chromatography may be used for further purification.
Equation 12 illustrates the conversion of the bromoheterocycle of Formula XVI to the corresponding lithium anion of Formula XVIIa by reaction of XVI with n-butyllitium or t-butyllithium (two equivalents or more) and the conversion of XVIIa, which is formed in situ, to the acid of Formula III (M is H), by reaction of XVIIa with carbon dioxide followed by acidifying with an acid such as hydrochloric acid.
Equation 12 ##STR24## wherein A' is as previously defined.
The reaction of Equation 12 is best carried out at a temperature between about -110.degree. C. to 70.degree. C. in an inert aprotic solvent such as ether or THF, to which an aqueous acid such as hydrochloric acid is later added. The products may be isolated by evaporation of the solvent followed by washing the residue with water and ether. Crystallization or chromatography may be used for further purification.
The esters of Formula XVa (A is A-1, Z.sub.1 is not N-O) can be synthesized by the methods shown below in Equations 13, 14, 15, 16 and 17. ##STR25## wherein Z.sub.1 ' is C-U or N; and
X, Y, Z, Z.sub.2 and R.sub.35 are as previously defined.
Equation 13 illustrates the reaction of .beta.-dicarbonyl compounds of Formula XVIII (or their equivalent) with an aminoazole ester of Formula XIX to give the desired esters of Formula XVa (X is X.sub.1, Y is Y.sub.1, Z is C-U, Z.sub.1 is not N-O).
Equation 13 ##STR26## wherein X.sub.1 or Y.sub.1 is H, C.sub.1 -C.sub.4 alkyl, C.sub.2 -C.sub.5 alkoxyalkyl, C.sub.2 -C.sub.5 alkylsulfinylalkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.2 -C.sub.5 alkylsulfonylalkyl, C.sub.3 -C.sub.5 cycloalkyl, C.sub.2 -C.sub.4 alkynyl, C.sub.2 -C.sub.5 alkylthioalkyl. ##STR27## U, Z.sub.1, Z.sub.2 and R.sub.35 are as previously defined.
The reaction of Equation 13 is best carried out under the conditions taguth by D. E. O'Brien, et al., in J. Med. Chem., 17, 645 (1974), P. Guerret, et al., in Bull. Soc. Chim. Fr., (3) 1031 (1971), and Yasuo Makisumi in Chem. Pharm. Bull., 10, 612 (1962).
Equation 14 illustrates the reaction of aminoazole esters of Formula XIX with compounds of Formula XX to give the desired esters of Formula XVa (A is A-1, Z is N and Z.sub.1 is not N-O).
Equation 14 ##STR28## wherein Z.sub.1 ', Z.sub.2, R.sub.35, X.sub.1 and Y.sub.1 are as previously defined; and
R.sub.36 is C.sub.1 -C.sub.4 alkyl.
The reaction of Equation 14 is best carried out in an inert solvent such as toluene in the presence of an acid such as p-toluenesulfonic acid at a temperature between about 0.degree. C. to 111.degree. C. The products may be isolated by washing the reaction solution with an aqueous sodium carbonate solution, drying (MgSO.sub.4) and concentrating the reaction solution. Crystallization and chromatography may be used for further purification of the products.
Equation 15 illustrates the reaction of aminoazole esters of Formula XIX with an imidate of Formula XXI to give the amidines of Formula XXII and the reaction of the amidines of Formula XXII with ortho esters of Formula XXIII to give the desired heterocyclic esters of Formula XVa (X is X.sub.1, Y is Y.sub.1, Z is N, Z.sub.1 is not N-O).
Equation 15 ##STR29## wherein Z.sub.1 ', Z.sub.2, R.sub.35, X.sub.1, R.sub.36 and Y.sub.1 are as previously defined; and
R.sub.37 is C.sub.1 -C.sub.4 alkyl.
The reaction of Equation 15 is best carried out under the condition taught by Keitaro Senga. et al., in J. Med Chem., 25, 243 (1982).
Compounds of Formula XVa (X is X.sub.2, Z.sub.1 is not N-O) can be prepared as shown below in Equation 16 by reaction of chlorosubstituted heterocyclic carboxylic acid esters of Formula XVa (X is Cl, Z.sub.1 is not N-O) with nucleophiles of Formula .sup.31 X.sub.2.
Equation 16 ##STR30## wherein Y, Z, Z.sub.1 ', Z.sub.2, and R.sub.35 are as previously defined;
X.sub.2 is C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, halogen, C.sub.2 -C.sub.5 alkoxyalkoxy, amino, C.sub.1 -C.sub.3 alkylamino, di(C.sub.1 -C.sub.3 alkyl)amino, C.sub.2 -C.sub.4 alkynyl, C.sub.3 -C.sub.4 alkenyloxy, C.sub.3 -C.sub.4 alkynyloxy, or N(OCH.sub.3)CH.sub.3.
The reaction of Equation 16 is best carried out in an inert solvent such as dimethylformamide or an alcohol. The products may be isolated by evaporating the reaction solvent and washing the residue with water. Chromatography may be used for further purification of the products.
Compounds of Formula XVa (Y is Y.sub.2, Z.sub.1 is not N-O) can be prepared as shown below in Equation 17 by reacting chlorosubstituted heterocyclic carboxylic acid esters of Formula XVa (Y is Cl, Z.sub.1 is not N-O) with nucleophiles of Formula .sup.- Y.sub.2.
Equation 17 ##STR31## wherein X, Z, Z.sub.1 ', Z.sub.2 and R are as previously defined;
Y.sub.2 is C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, halogen, C.sub.2 -C.sub.5 alkoxyalkoxy, amino, C.sub.1 -C.sub.3 alkylamino, di(C.sub.1 -C.sub.3 alkyl)amino, C.sub.3 -C.sub.4 alkenyloxy, C.sub.3 -C.sub.4 alkynyloxy, C.sub.2 -C.sub.4 alkynyl or N(OCH.sub.3)CH.sub.3.
The reaction of Equation 17 is best carried out in an inert solvent such as dimethylformamide or an alcohol. The products can be isolated by evaporating the reaction solvent and washing the residue with water. Chromatography may be used for further purification of the products.
Compounds XVa (X is Cl and Z.sub.1 is not N-O) and XVa (Y is Cl and Z.sub.1 is not N-O) can be prepared from dichloroheterocyclic carboxylic acid esters of Formula XVa (X is Cl and Y is Cl, and Z.sub.1 is not N-O) by nucleophilic displacement reactions with an appropriate nucleophile by methods known in the art or by obvious modifications of these known methods. ##STR32## wherein Z, Z.sub.1 ', Z.sub.2 and R.sub.35 are as previously defined.
Alternatively, they can be prepared by reacting the corresponding hydroxy compounds of Formula XXIII or XXIV with POCl.sub.3 or by other well-known methods or by obvious modification of these known methods. ##STR33## wherein X, Y, Z, Z.sub.1 ', Z.sub.2 and R.sub.35 are as previously defined.
Compound XVa (X is Cl, Y is Cl and Z.sub.1 is not N-O) can be prepared by reacting the corresponding dihydroxy compounds of Formula XXV with POCl.sub.3 by methods well known in the art. ##STR34## wherein Z, Z.sub.1 ', Z.sub.2 and R.sub.35 are as previously defined.
The compounds XXIII (Z is C-U and Z is not N-O), XXIV (XZ is C-U and Z.sub.1 is not N-O) or XXV (Z is C-U and Z is not N-O) can be prepared by condensation of a .beta.-keto ester, a malonatediester or one of their equivalents with 3-amino-4-carboalkoxypyrazoles as taught by:
1. Yasuo Makisumi in Chem. Pharm. Bull., 10, 612 (1962);
2. Keitaro Senga et all. in J. Med. Chem., 24(5), 61a (1971);
3. Alfred Dornow and Klaus Dehmer in Chem. Ber., 100(8), 2577 (1967);
4. Mohamed Elnagdi in Arch. Pharm., 316(8), 713 (1983);
5. B. B. Gavrilenko in Zh. Org. Khim., 18(5), 1079 (1982);
or by modifications of these methods (e.g., reaction of 3-amino-4-carbethoxypyrazole with diketene).
The compounds XXIII (Z is N, Z.sub.1 is not N-O), XXIV (Z is N, Z.sub.1 is not N-O) or XXV (Z is N, Z.sub.1 is not N-O) can be similarly prepared by condensation of carbonylisocyanates of Formula XXVI or the compounds of Formula XXVII with aminoazole esters of Formula XIXX. ##STR35## wherein J is H, Cl, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.2 -C.sub.5 alkoxyalkyl, C.sub.2 -C.sub.5 alkylsulfinylalkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.2 -C.sub.5 alkylsulfonylalkyl, C.sub.3 -C.sub.5 cycloalkyl, C.sub.2 -C.sub.4 alkynyl, C.sub.2 -C.sub.5 alkylthioalkyl, ##STR36## R.sub.36 and R.sub.37 are independently C.sub.1 -C.sub.4 alkyl; and Y.sub.1 is as previously defined.
The esters of formula XVa (A is A-1, Z.sub.1 is N-O) can be synthesized by oxidation of esters of Formula XVa (A is A-1, Z.sub.1 is N) with an oxidizing agent such as m-chloroperoxybenzoic acid. ##STR37## wherein X, Y, Z, Z.sub.2 and R.sub.35 are as previously defined.
The bromoheterocycles of Formula XVIa (A is A-1) can be synthesized by the same methods as those for the preparation of the esters of Formula XVa (A is A-1) using the aminobromoazoles of Formula XXVIII instead of the aminoazole esters of Formula XIX as starting material. ##STR38## wherein X, Y, Z, Z.sub.1, Z.sub.1 ', Z.sub.2 and R.sub.35 are as previously defined.
Alternatively, the bromoheterocycles of Formula XVIa can be synthesized by bromination of the heterocycles of Formula XXXXV with a brominating agent such as bromine or N-bromosuccinimide as shown in Equation 17b.
Equation 17b ##STR39## wherein X, Y, Z, Z.sub.1 and Z.sub.2 are as previously defined.
The reaction of Equation 17b is best carried out in an inert solvent such as chloroform or carbon tetrachloride at a temperature between 0.degree. C. to 77.degree. C. The products can then be isolated by filtration, concentration of the filtrate and washing the residue with water. Crystallization or chromatography may be used for further purification if desired.
The bromoheterocycles of Formula XVIb (A is A-2) can be synthesized from aminobromoheterocycle of Formula XXX by similar methods as discussed for the preparation of the heterocyclic esters of Formula XVa (A is A-1) from aminoazole esters of Formula XIX. ##STR40## wherein X, Y, Z, Z.sub.1, Z.sub.1 ' and Z.sub.2 are as previously defined.
For example, reaction of the aminobromoazoles of Formula XXX with a .beta.-dicarbonyl compounds of Formula XVIII (or its equivalent) should give the bromoheterocycles of Formula XVIb (X is X.sub.1, Y is Y.sub.1, Z is C-U and Z.sub.1 is C-U or N) as shown in Equation 17a.
Equation 17a ##STR41## wherein X.sub.1, Y.sub.1, U, Z.sub.1 ', Z.sub.2 and R are as previously defined.
The reaction of Equation 17a is best carried out under the conditions taught by Takayuki Okabe, et al., in J. Heterocyclic. Chem., 20, 735 (1983).
Alternatively, the bromoheterocycles of Formula XVIb (A is A-2) can be synthesized by bromination of the heterocycles of Formula XXXI with a brominating agent such as bromine or N-bromosuccinimide as shown below in Equation 18.
Equation 18 ##STR42## wherein X, Y, Z, Z.sub.1 and Z.sub.2 are as previously defined.
The reaction of Equation 18 is best carried out in an inert solvent such as chloroform or carbontetrachloride at a temperature between about 0.degree. C. to 77.degree. C. The products can then be isolated by filtration, concentration of the filtrate and washing the resulting residue with water. Crystallization or chromatography may be used for further purification, if desired.
The compounds of Formula VIII can be prepared by methods known in the art such as those taught by Tetsuzo Kato, et al. in Yakugaku Zasshi, 93, (11), 1437 (1973), Roman Balicki, et al. in Pol. J. Chem., 54, 2175 (1980), Roman Balicki in Pol. J. Chem., 55, 1995 (1981) and 57, 1251 (1983), D. J. Brown, et al. in J. Chem. Soc., Perkin Trans. 1, 1819 (1972), Hiroshi Yamamoto, et al. in Bull. Chem. Soc. Jpn., 50 (2), 453 (1977), A. N. Kost, et al. in Khim. Geterotsikl. Soedin., 4, 558 (1977) and Jean Imbach, et al. in Bull. Soc. Chim. Fr., (5) 1929 (1970) or by modifications of these methods. ##STR43## wherein X, Y, Z, Z.sub.1 and Z.sub.2 are as previously defined.
The heterocyclic esters of Formula XVb (A is A-4) can be synthesized from the aminoheterocyclic esters of Formula XXXII by similar methods as discussed for the preparation of the heterocyclic esters of Formula XVa (A is A-1) from aminoazole esters of Formula XIX. For example, reaction of the aminoheterocyclic esters of Formula XXXII with a .beta.-dicarbonyl compound of Formula XVIII should give the desired esters of Formula XVb (A is A-4, X is X.sub.1, Y is Y.sub.1, Z is C-U) as shown below in Equation 19.
Equation 19 ##STR44## wherein X.sub.1, U, Y, Z.sub.4, Z.sub.1 and R.sub.35 are as previously defined.
The reaction of Equation 19 is best carried out under the conditions taught by A. Z. Britten, et al. in Chem. Ind., 6, 278 (1973).
The bromoheterocycles of Formula XVIc (A is A-4) can be synthesized from the aminobromoheterocycles in the same way as discussed previously for the preparation of the heterocyclic esters of Formula XVa (A is A-1) from the aminoheterocyclic esters of Formula XIX. Alternatively, compounds of Formula XXXIII can be converted to the bromoheterocycles of Formula XVIc (Z is N). For example, reaction of compounds of Formula XXXIII (X.sub.3 is CH.sub.3, Y.sub.3 is CH.sub.3) with HCO.sub.2 NH.sub.4 gives the desired bromoheterocycles of Formula XXIc (Z is N, X is CH.sub.3, Y is CH.sub.3) as shown below. ##STR45## wherein X, Y, Z.sub.4 and Z.sub.1 are as previously defined;
X.sub.3 is X.sub.1 or C.sub.1 -C.sub.4 alkoxy; and
Y.sub.3 is Y.sub.1 or C.sub.1 -C.sub.4 alkoxy.
Equation 20 ##STR46##
The reaction of Equation 20 is best carried out under the conditions taught by Guy Ah-Kon, et al., in C. R. Acad. Sci., Ser. C., 278 (26), 1513 (1974).
The compounds of Formula XVc (A is A-6) and Formula XVId (A is A-6) can be prepared from compounds of Formula XXXIV, Formula XXXV and Formula XXXVI by similar chemistry as taught previously for the preparation of compounds of Formula XVb and Formula XVIc. ##STR47## wherein X, Y, Z, X.sub.3, Y.sub.3, Z.sub.1, Z.sub.4 and R.sub.35 are as previously defined.
The bromoheterocycles of Formula XVIe (A is A-5) can be prepared from compounds of Formula XXXVII and Formula XXXVIII through similar chemistry as taught previously for the preparation of compounds of Formula XVIC. ##STR48## wherein X, Y, X.sub.3, Y.sub.3, Z, Z.sub.1, Z.sub.2 and Z.sub.3 are as previously defined.
The heterocyclic esters of Formula XVd (A is A") and the bromoheterocycles of Formula XVIf (A is A") can be prepared by modifications of those methods discussed previously. ##STR49## wherein A" is A-8, A-9, A-12, A-13, A-14, A-15, A-16, A-17 and A-19; and
R.sub.35 is as previously defined.
The bromoheterocycles of Formula XVIg (A is A-11) can be prepared from compounds of Formula XXXIX. For example, reaction of compounds of Formula XXXIX with triethylorthoacetate gives the desired bromoheterocycles of Formula XVIg (A is A-11, X is CH.sub.3) as shown below. ##STR50## wherein X, Z.sub.1, Z.sub.2 and Z.sub.3 are as previously defined.
Equation 21 ##STR51## wherein Z.sub.1, Z.sub.2 and Z.sub.3 are as previously defined.
The reaction of Equation 21 is best carried out in an inert solvent such as acetic acid at a temperature between about 20.degree. C. to 118.degree. C.
The products may be isolated by evaporation of the solvent, followed by chromatography or crystallization of the residue.
The bromoheterocycles of Formula XVIh (A is A-16) can be prepared from compounds of Formula XXXX. For example, reaction of some of the compounds of Formula XXXX with 2,3-butadione gives the desired products of Formula XVIh (X is CH.sub.3, Y is CH.sub.3) as shown below in Equation 22. ##STR52## wherein X, Y, Z.sub.1 and Z.sub.2 are as previously defined.
Equation 22 ##STR53## wherein Z.sub.1 and Z.sub.2 are as previously defined.
The reaction of Equation 22 is best carried out in an inert solvent such as toluene in the presence of an acid catalyst such as p-toluenesulfonic acid, if necessary, at a temperature between about 0.degree. C. to 120.degree. C. The products may be isolated by evaporation of the solvent, followed by chromatography or recrystallization of the residue.
The bromoheterocycles of Formula XVIi (A is A-7) and the heterocyclic esters of Formula XVe (A is A-7) may be prepared by modification of methods taught by H. J. Metz, et al. in Chem. Ber., 115 (8), 2807 (1982). ##STR54## wherein X.sub.a, Y, Z, Z.sub.1, Z.sub.2 and R.sub.35 are as previously defined.
The heterocycles of Formula XXXI can be prepared by the methods taught by Takayuki Okabe, et al. in J. Heterocyclic. Chem., 20, 735 (1983), W. Flitsch, et al., in Liebigs Ann. Chem., 735 35 (1970) and M. Zapan, et al., in J. Heterocyclic Chem., 8 1 (1971) or by modification of these methods.
The heterocycles of Formula XXXIa (Z.sub.1 is N, Z.sub.2 is N) can be prepared by the reaction of compounds of Formula XXXXI with orthoformate of Formula XXXXII as shown below in Equation 23.
Equation 23 ##STR55## wherein R is lower alkyl; and
X, Y and Z are as previously defined.
The reaction of Equation 23 is best carried out in an inert solvent such as toluene at a temperature between about 0.degree. C. to 120.degree. C. The product can be isolated by evaporation of the reaction solvent and orthoformate. Crystallization or chromatography may be used for further purification of the products.
The heterocycles of Formula XXXIb (Z.sub.1 is N, Z.sub.2 is C-U) can be prepared by the reaction of compounds of Formula XXXXIII with an .alpha.-halocarbonyl compound of Formula XXXXIV as shown in Equation 24.
Equation 24 ##STR56## wherein X, Y, Z, U and V are as previously defined.
The reaction of Equation 24 is best carried out in an inert solvent such as N,N-dimethylformamide at a temperature between about 0.degree. C. to 160.degree. C. The products can be isolated by evaporation of the reaction solvent and washing the residue with other solvent such as hexane or ether. Crystallization or chromatography may be used for further purification, if desired.
The heterocycles of Formula XXXXV (A is A-1) can be synthesized by the same methods as those for the preparation of the esters of Formula XVa (A is A-1) using the aminoazole of Formula XXXXVI instead of the aminoazole esters of Formula XIX as starting material. ##STR57## wherein X, Y, Z, Z.sub.1, Z.sub.1 ', Z.sub.2 and R.sub.35 are as previously defined.
The compounds of Formula XVIII, XIX, XX, XXI, XXVI, XXVII, XXVIII, XXX, XXXII, XXXIII, XXXIV, XXXV, XXXVI, XXXVII, XXXVIII, XXXIX, XXXX, XXXXI, XXXXII, XXXXIII, XXXXIV and XXXXVI can be prepared by methods known in the art or by obvious modification of these known methods.

EXAMPLE 1
2-(((((5,7-Dimethylpyrazolo((1,5-A))pyrimidine-3-yl)carbonylamino))sulfonyl))benzoic acid, methyl ester
To 1.9 g of 5,7-dimethylpyrazolo(1,5-A)pyrimidine-3-carboxylic acid in 10 mL of methylene chloride at 0.degree. C. was added dropwise 0.5 mL of pyridine and then a solution of 1 mL of thionyl chloride in 3 mL of methylene chloride. The resultant solution was stirred at room temperature for 12 hours. The reaction solution was then concentrated under reduced pressure. To the resultant residue was added 30 mL of anhydrous methylene chloride. To this solution at 5.degree. C. was added portionwise 2.1 g of methyl 2-(aminosulfonyl)benzoate followed by 1.1 g of triethylamine. The resulting mixture was stirred at room temperature for 18 hours followed by concentration under reduced pressure. The resultant residue was stirred in 100 mL of aqueous 1.0M sodium carbonate solution for 0.5 hour. The resultant suspension was then filtered. The filtrate was washed with ether followed by acidification with concentrated hydrochloric acid to pH<3. The mixture was then stirred for 15 minutes and the resultant suspension was filtered. The solid collected was washed with water and then ether to give, after being dried in oven at 80.degree. C. for 2 hours, 1.14 g of the desired product, m.p. 204.degree.-207.degree. C.
NMR(DMSO-d.sub.6).delta.: 2.67 (s, 3H); 2.73 (s, 3H); 3.83 (s, 3H); 7.28 (s, 1H); 7.6-8.36 (m, 4H); 8.36 (s, 1H); and 11.2 (bs, 1H).
EXAMPLE 2
N-((2-(Methylsulfonyl)phenylsulfonyl)-5,7-dimethylpyrazolo((1,5-A))pyrimidine-3-carboxamide
To 1.9 g of 5,7-dimethylpyrazolo(1,5-A)pyrimidine-3-carboxylic acid in 10 mL of methylene chloride at 0.degree. C. was added dropwise 0.5 mL of pyridine and then a solution of 1 mL of thionyl chloride in 3 mL of methylene chloride. The mixture was then stirred at room temperature for 12 hours, and then concentrated under reduced pressure. To the residue was added 30 mL of anhydrous methylene chloride. To the resultant solution at 5.degree. C. was added 2.3 g of 2-(methylsulfonyl)benzenesulfonamide and then 1.1 g of triethylamine. The reaction mixture was stirred at room temperature for 18 hours and then concentrated under reduced pressure. The residue was then stirred in 100 mL of aqueous 1.0M sodium carbonate aqueous solution for 0.5 hour. The resulting suspension was filtered. The filtrate was washed with ether and then acidified with concentrated hydrochloric acid to pH<3. The resulting suspension was filtered. The filtered solid was washed with water and then ether to yield, after being dried in oven at 80.degree. C. for 2 hours, 0.31 g of the desired product, m.p. 230.degree.-233.degree. C.
NMR(DMSO-d.sub.6).delta.: 2.64 (s, 3H); 2.71 (s, 3H); 3.47 (s, 3H); 7.22 (s, 1H); 8.0-8.5 (m, 4H), 8.57 (s, 1H); and 11.30 (bs, 1H).
EXAMPLE 3
N-((2-(1-Ethyl-1H-tetrazol-5-yl)phenylsulfonyl))pyrazolo((1,5-A))pyrimidine-3-carboxamide
To 0.57 g of 5,7-dimethylpyrazolo(1,5-A)pyrimidine-3-carboxylic acid in 15 ml of chloroform was added 0.53 g of 1,1-carbonyldiimidazole. The resulting mixture was stirred at 55.degree. C. for 3.5 hours. To the reaction solution was then added 0.75 g of 2-(1-ethyl-1H-tetrazol-5-yl)benzenesulfonamide followed by 0.4 g of triethylamine. The resulting solution was stirred at 55.degree. C. for 40 hours and was then heated at reflux for 15 hours. The reaction mixture was then allowed to cool to room temperature and was concentrated under reduced pressure. The residue was added to 21 mL of water. To the aqueous suspension was then added dropwise 10% aqueous hydrochloric acid until the pH of the aqueous solution became .about.3. The suspension which formed was stirred at room temperature for another 20 minutes and was then filtered. The solid collected was washed with water and the ether to give, after being dried in an oven at 80.degree. C. for 2 hours, 0.73 g of the desired product, m.p. 233.degree.-236.degree. C.
NMR(DMSO-d.sub.6).delta.: 1.54 (t, 3H); 2.79 (s, 3H); 2.80 (s, 3H); 4.27 (q, 2H); 6.85 (s, 1H); 7.41 (m, 1H); 7.82 (m, 2H); 8.50 (s, 1H); and 8.65 (m, 1H).
EXAMPLE 4
2-(((2,4-Dimethylimidazo((1,5-a))pyrimidine-8-ylcarbonyl)aminosulfonyl))benzoic acid, methyl ester
To 0.55 g of 2,4-dimethylimidazo((1,5-a)pyrimidine-8-carboxylic acid in 21 ml of acetonitrile at room temperature was added 0.8 g of triethylamine and then 0.86 of 2-chloro-1-methylpyridinium iodide. The mixture was then stirred at room temperature for 30 minutes. To this mixture was then added 0.9 g of methyl 2-(aminosulfonyl)benzoate followed by 0.4 g of triethylamine. The resulting mixture was stirred at room temperature for 12 hours and was then filtered. The solid collected was stirred in ether and was then filtered. The filtrate was combined and was concentrated under reduced pressure. The resultant residue was stirred in 15 ml of water and was acidified with 10% HCl aqueous solution until pH .about.2 while being cooled in an ice/water bath. To this suspension was then added 20 ml of ether. The mixture was stirred at room temperature for 1 hour and was then filtered. The solid collected was washed with water and then ether, to give, after being dried in oven at 50.degree. C. for 12 hours, 0.35 g of the desired product, m.p. 228.degree.-230.degree. C.
NMR(DMSO-d.sub.6).delta.: 2.60 (s, 3H); 2.69 (s, 3H); 3.83 (s, 3H); 6.69 (s, 1H); 7.6-7.9 (m, 3H); 8.2 (m, 1H); and 8.53 (s, 1H),
EXAMPLE 5
2,4-Dimethylimidazo((1,5-a)pyrimidine-8-carboxylic acid
To a suspension of 1.25 g of 2,4-dimethylimidazo((1,5-a))pyrimidine-8-carboxylic acid, ethyl ester in 7 ml of ethanol was added a solution of 1 g of potassium hydroxide in 4 ml of water. The reaction mixture was then heated at reflux for 45 minutes and was then concentrated under reduced pressure. The residue was dissolved in water (.about.15 ml) and was acidified with 10% HCl until pH .about.3 while being cooled in an ice/water bath. The solid formed was collected by filtration and was washed with water and ether to give, after being dried in oven at 50.degree. C. for 12 hours, 0.98 g of the desired product, m.p. 248.degree.-249.degree. C.
NMR(DMSO-d.sub.6).delta.: 2.49 (s, 3H); 2.64 (s, 3H); 6.8 (s, 1H); 8.34 (s, 1H); and 12.0 (bs, 1H).
EXAMPLE 6
2-(((((5,7-Dimethyl-((1,2,3))-triazolo((1,5-a)pyrimidine-3-yl)carbonylamino))sulfonyl))benzoic acid, methyl ester
To 0.55 g of 5,7-dimethyl-((1,2,3))-triazolo((1,5-a))pyrimidine-3-carboxylic acid in 16 ml of acetonitrile was added 1 g of 2-chloro-1-methylpyridinium iodide. To this mixture was then added 0.96 g of triethylamine in 5 ml of acetonitrile dropwise. The mixture was stirred at room temperature for 30 minutes. To this mixture was then added 1.08 g of methyl 2-(aminosulfonyl)benzoate followed by 0.47 g of triethylamine. The resulting mixture was stirred at room temperature for 12 hours and was then filtered. The solid collected was stirred in ether and was then filtered. The filtrate was combined and was concentrated under reduced pressure. The resultant residue was stirred in 15 ml of water and was acidified with 10% HCl aqueous solution until pH .about.3 while being cooled in an ice/water bath. To this suspension was then added 30 ml of ether. The mixture was stirred at room temperature for 1 hour and was then filtered. The solid collected was washed with water and then ether to give, after being dried in oven at 50.degree. C. for 12 hours, 0.54 g of a solid, m.p. 228.degree.-230.degree. C. This solid was then further purified by flash column chromatography (silica gel, 4% methanol in methylene chloride as eluent) to give 0.17 g of the desired product, m.p. 193.degree.-195.degree. C.
NMR(DMSO-d.sub.6).delta.: 2.65 (s, 3H); 2.85 (s, 3H); 3.83 (s, 3H); 7.34 (s, 1H); 7.60-7.85 (m, 3H); 8.21 (m, 1H); and 11.65 (bs, 1H).
EXAMPLE 7
5,7-Dimethyl-((1,2,3))-triazolo((1,5-a))pyrimidine-3-carboxylic acid
To a solution of 4.37 g of 5,7-dimethyl-((1,2,3))triazolo((1,5-a))pyrimidine-3-carboxylic acid, ethyl ester in 30 ml of ethanol was added a solution of 3 g of potassium hydroxide in 12 ml of water. The resulting solution was heated at reflux for 1 hour and was then cooled down to room temperature. The ethanol was then removed under reduced pressure. Water was then added to the residue until the volume reached 50 ml. The aqueous solution was washed with 75 ml of CH.sub.2 Cl.sub.2 and was then acidified with cooling (ice/water bath) with concentrated hydrochloric acid until pH .about.3. The resulting suspension was stirred for another 5 minutes and was then filtered. The solid collected was washed with water and then ether to give, after being dried in oven at 50.degree. C. for 12 hours, 3 g of the desired product, m.p. 137.degree.-138.degree. C.
NMR(DMSO-d.sub.6).delta.: 2.7 (s, 3H); 2.9 (s, 3H); 7.04 (s, 1H); and 13.0 (bs, 1H).
EXAMPLE 8
5,7-Dimethyl-((1,2,3))-triazolo((1,5-a))pyrimidine-3-carboxylic acid, ethyl ester
To 300 ml of ethanol was added 23.3 g of 5-amino-1H-((1,2,3))-triazolo-4-carboxylic acid, ethyl ester, 47 g of 2,4-pentanedione and 4 ml of piperidine. The reaction mixture was then heated at reflux for 4 hours. To the reaction solution was then added 47 g of 2,4-pentanedione. The reaction solution was then refluxed for another 12 hours. To the reaction solution was then added another 21 ml of 2,4-pentanedione and the reaction solution was refluxed for another 8 hours. An additional 21 ml of 2,4-pentanedione was then added and refluxing was continued for another 12 hours. The reaction solution was then cooled to room temperature and was concentrated under reduced pressure. The residue was stirred in 300 ml of hexanes for 30 minutes and was filtered. The solid collected was washed with hexanes and was dried in oven at 50.degree. C. for 12 hours to give 30.4 g of the desired product, m.p. 174.degree.-176.degree. C.
NMR(CDCl.sub.3).delta.: 1.5 (t, 3H); 2.77 (s, 3H); 2.97 (s, 3H); 4.54 (q, 2H); and 6.93 (s, 1H).
EXAMPLE 9
2-(((((5,7-Dimethyl-((1,2,4))-triazolo((1,5-a))pyrimidin-2-yl)carbonylamino))sulfonyl))benzoic acid, methyl ester
To a suspension of 0.51 g of 5,7-dimethyl((1,2,4))-triazolo((1,5-a))pyrimidine-2-carboxylic acid in 16 ml of acetonitrile was added 0.86 g of 2-chloro-1-methylpyridinium iodide. To this mixture was then added 0.8 g of triethylamine in 5 ml of acetonitrile. The reaction mixture was then stirred at room temperature for 30 minutes. To this mixture was then added 0.9 g of methyl 2-(aminosulfonyl)benzoate followed by 0.4 g of triethylamine. The resulting mixture was stirred at room temperature for 2 days and was then concentrated under reduced pressure. The residue was stirred in 15 ml of water and was acidified with 10% HCl aqueous solution until pH .about.3 while being cooled in an ice/water bath. The solid formed was collected by filtration, washed with water and then ether, and dried in oven at 50.degree. C. for 12 hours to give 0.65 g of the desired product, m.p. 227.degree.-229.degree. C.
NMR(DMSO-d.sub.6).delta.: 2.61 (s, 3H); 2.72 (3, 3H); 3.85 (s, 3H); 7.33 (s, 1H); 7.6-7.85 (m, 3H); and 8.2 (m, 1H).
EXAMPLE 10
5,7-Dimethyl-((1,2,4))-triazolo((1,5-a))pyrimidine-2-carboxylic acid
To 4 g of 5,7-dimethyl-((1,2,4))-triazolo(1,5-a)pyrimidine-2-carboxylic acid, ethyl ester, in 20 ml of ethanol was added a solution of 1.3 g of potassium hydroxide in 10 ml of water. An additional 10 ml of ethanol was then added. The reaction mixture was heated at 55.degree. C. for 2 hours and was then concentrated under reduced pressure. The residue was stirred in 20 ml of water and was acidified with 1N HCl aqueous solution until pH.about.1 while being cooled in an ice/water bath. The solid formed was collected by filtration, washed with water and then ether, and was dried in oven at 50.degree. C. for 12 hours to give 0.82 g of the desired product, m.p. 188.degree.-189.degree. C.
NMR(DMSO-d.sub.6).delta.: 2.59 (s, 3H); 2.73 (s, 3H); 7.27 (s, 1H); and 13-14 (bs, 1H).
EXAMPLE 11
5,7-Dimethyl-((1,2,4))-triazolo((1,5-a))pyrimidine-2-carboxylic acid, ethyl ester
To 11.7 g of 5-amino-1H-((1,2,4))-triazolo-3-carboxylic acid, methyl ester in 150 ml of ethanol was added 16 g of 2,4-pentanedione and 4 ml of piperidine. The resulting mixture was refluxed for 2.5 days under nitrogen. The mixture was then cooled down to room temperature and was filtered. The solid collected was washed with ether and was dried in oven at 50.degree. C. for 12 hours to give 9.35 g of the desired product, m.p. 180.degree.-181.degree. C.
NMR(CDCl.sub.3).delta.: 1.47 (t, 3H); 2.70 (s, 3H); 2.86 (s, 3H); 4.56 (q, 2H); and 6.91 (s, 1H).
EXAMPLE 12
N-(((2-Chlorophenyl)-sulfonyl))-5,7-dimethoxypyrazolo-((1,5-a))pyrimidine-3-carboxamide
To 0.8 g of 3-bromo-5,7-dimethoxypyrazolo(1,5-a)pyrimidine in 40 ml of tetrahydrofuran at -70.degree. C. under nitrogen was added dropwise 4.3 ml of 1.7M t-butyllithium in pentane. The resulting mixture was stirred at -70.degree. C. under N.sub.2 for 15 minutes. To this solution at -70.degree. C. was then added 0.75 g of 2-chlorobenzenesulfonyl isocyanate. The resulting mixture was stirred at -60.degree. C. for 30 minutes and was then allowed to warm up to room temperature. The mixture was stirred at room temperature for another 5 minutes and was then concentrated under reduced pressure. The residue was then stirred in 30 ml of water and was then filtered. The filtrate was then acidified with 10% HCl aqueous solution until pH.about.2 while being cooled in an ice/water bath. The solid was collected by filtration, washed with water and then a mixture of ether and hexane (1:1), and further purified by flash column chromatography (silica gel; 5%, 10%, 20% ether in CH.sub.2 Cl.sub.2 and then acetonitrile) to give 0.02 g of the desired product, m.p. 186.degree.-190.degree. C.
NMR(CDCl.sub.3).delta.: 4.17 (s, 3H); 4.21 (s, 3H); 5.9 (s, 1H); 7.6 (m, 3H); 8.38 (s, 1H); and 8.4 (m, 1H).
EXAMPLE 13
3-Bromo-5,7-dimethoxypyrazolo(1,5-a)pyrimidine
To a solution of 1.2 g of sodium dissolved in 60 ml of methanol was added 6.7 g of 3-bromo-5,7-dichloropyrazolo(1,5-a)pyrimidine. The resulting mixture was stirred at room temperature for 12 hours and was then concentrated under reduced pressure. The residue was then stirred in water and was then filtered. The solid collected was washed with ether and was dried in oven at 50.degree. C. for 12 hours to give 5.24 g of the desired product, m.p. 188.degree.-190.degree. C.
NMR(CDCl.sub.3).delta.: 4.05 (s, 3H); 4.14 (s, 3H); 5.7 (s, 1H); and 7.94 (s, 1H).
EXAMPLE 14
3-Bromo-5,7-dichloropyrazolo(1,5-a)pyrimidine
To a solution of 5.3 g of 5,7-dichloropyrazolo(1,5-a)pyrimidine in 70 ml of chloroform was added portionwise 6 g of N-bromosuccinimide while keeping the temperature below 40.degree. C. The resulting solution was refluxed for 30 minutes and was then stirred at room temperature for 12 hours. The suspension was then filtered. The filtrate was washed with 50 ml of cold 10% sodium hydroxide aqueous solution twice and was then dried over MgSO.sub.4. The chloroform solution was then concentrated under reduced pressure to give 7.47 g of the desired product, m.p. 73.degree.-75.degree. C.
NMR(CDCl.sub.3).delta.: 7.02 (s, 1H) and 8.18 (s, 1H).
EXAMPLE 15
Methyl 2-((6,8-dimethylimidazo[1,2-b]pyridazin-3-ylcarbonyl)aminosulfonyl)benzoate
To a solution of 2.0 g (8.8 mmol) of 3-bromo-6,8-dimethylimidazo[1,2-b]pyridazine in 50 mL of tetrahydrofuran at -78.degree. C. was added 6.1 mL (9.7 mmol) of a 1.6M solution of n-butyllithium in hexanes. After 15 min, carbon dioxide was bubbled through the solution for 10 min. After warming to room temperature, the solid material was isolated by filtration and washed with 1 mL of water. After drying overnight in a vacuum desiccator, 1.48 g of a solid was obtained.
To a slurry of 0.5 g (2.5 mmol) of the solid obtained above in 8 mL of dichloromethane was added 1 mL oxalyl chloride. This mixture was heated to reflux for 2 h. After cooling, the volatiles were removed with a rotary evaporator and vacuum pump. The residue was dissolved in 6 mL of dichloromethane and was cooled in an ice bath. To this solution was added 0.55 g (2.5 mmol) of methyl 2-(aminosulfonyl)-benzoate and 0.36 mL (2.6 mmol) of triethylamine. The reaction was stirred 16 h at room temperature. To the reaction mixture was added 1 mL of water and the layers were separated. The organic layer was dried (Na.sub.2 SO.sub.4) and the solvent was removed with a rotary evaporator. The residue was purified by flash chromatography to give 0.33 g of the title compound as a yellow solid, m.p. 210.degree.-212.degree. C.
EXAMPLE 16
3-Bromo-6,8-dimethylimidazo[1,2-b]pyridazine
To a solution of 3.63 g (24.7 mmol) of 6,8-dimethylimidazo[1,2-b]pyridazine in 25 mL of chloroform was added 4.84 g (27.2 mmol) of N-bromosuccinimide. After 2 h. 1 mL of a saturated aqueous solution of sodium bicarbonate was added. The layers were separated. The organic layer was dried (Na.sub.2 SO.sub.4) and the solvent was removed with a rotary evaporator. The residue was purified by flash chromatography to give 4.66 g of the title compound as a while solid, m.p. 137.degree.-139.degree. C.
EXAMPLE 17
6,8-Dimethylimidazo[1,2-b]pyridazine
A mixture of 25 g (148 mmol) of bromoacetaldehyde dimethyl acetal, 5 mL of water and 5 mL of 48% HBr was refluxed 2 h. After cooling, it was poured into 50 mL of ethanol. Solid sodium bicarbonate was added until bubbling ceased. The mixture was filtered and to the filtrate was added 7.5 g (61 mmol) of 3-amino-4,6-dimethylpyridazine. After stirring 16 h, the ethanol was removed with a rotary evaporator. The residue was triturated with ethanol to give a brown solid which was dissolved in water and washed with dichloromethane. The aqueous layer was brought to pH 9 with sodium bicarbonate and extracted with dichloromethane. Drying (Na.sub.2 SO.sub.4) and solvent removal with a rotary evaporator gave 4 g of the title compound as a brown solid, m.p. 70.degree.-74.degree. C.
EXAMPLE 18
Methyl 2-((2,4-dimethylpyrrolo[1,2-b]pyridazin-7-ylcarbonyl)aminosulfonyl)benzoate
To a solution of 0.40 g (2.7 mmol) of 2,4-dimethylpyrrolo[1,2-b]pyridazine in 15 mL of dichloromethane at -78.degree. C. was added, by syringe pump over a period 70 min, a solution of 0.62 g (2.7 mmol) of methyl 2-(isocyanatosulfonyl)benzoate. The reaction mixture was allowed to warm to room temperature. The residue was purified by flash chromatography to give 0.12 g of a white solid, m.p. 200.degree.-202.degree. C.
The following compounds may be prepared by one skilled in the art by utilizing the procedures and examples shown above and obvious variations thereof.
______________________________________General Formulae______________________________________General Formula 1 ##STR58##General Formula 2 ##STR59##General Formula 3 ##STR60##General Formula 4 ##STR61##General Formula 5 ##STR62##General Formula 6 ##STR63##General Formula 7 ##STR64##General Formula 8 ##STR65##General Formula 9 ##STR66##General Formula 10 ##STR67##General Formula 11 ##STR68##General Formula 12 ##STR69##General Formula 13 ##STR70##General Formula 14 ##STR71##General Formula 15 ##STR72##General Formula 16 ##STR73##General Formula 17 ##STR74##General Formula 18 ##STR75##General Formula 19 ##STR76##whereinL-1a is ##STR77##L-1b is ##STR78##L-1c is ##STR79##L-1d is ##STR80##L-1e is ##STR81##L-1f is ##STR82##L-1g is ##STR83##L-1h is ##STR84##L-1i is ##STR85##L-1j is ##STR86##L-1k is ##STR87##L-1l is ##STR88##L-1m is ##STR89##L-1n is ##STR90##L-1o is ##STR91##L-1p is ##STR92##L-1q is ##STR93##L-1r is ##STR94##L-1s is ##STR95##L-1t is ##STR96##L-1u is ##STR97##L-1v is ##STR98##L-1w is ##STR99##L-1x is ##STR100##L-1y is ##STR101##L-1z is ##STR102##L-1aa is ##STR103##L-1ab is ##STR104##L-1ac is ##STR105##L-1ad is ##STR106##L-1ae is ##STR107##L-1af is ##STR108##L-3a is ##STR109##L-3b is ##STR110##L-4a is ##STR111##L-7a is ##STR112##L-8a is ##STR113##L-8b is ##STR114##L-9a is ##STR115##L-10a is ##STR116##L-12a is ##STR117##L-12b is ##STR118##L-12c is ##STR119##L-14a is ##STR120##L-15a is ##STR121##L-16a is ##STR122##L-16b is ##STR123##L-18a is ##STR124##L-20a is ##STR125##L-20b is ##STR126##L-20c is ##STR127##L-22a is ##STR128##L-25a is #STR129##______________________________________
TABLE 1__________________________________________________________________________General Formu1a 1Z Z.sub.1 Z.sub.2 W X Y R L m.p. (.degree.C.)__________________________________________________________________________CH N CH O CH.sub.3 CH.sub.3 H L-1a 204-207CH N CH O CH.sub.3 CH.sub.3 H L-1b 250-252CH N CH O CH.sub.3 CH.sub.3 H L-1c 227-232CH N CH O CH.sub.3 CH.sub.3 H L-1d 250-252CH N CH O CH.sub.3 CH.sub.3 H L-1eCH N CH O CH.sub.3 CH.sub.3 H L-1f 250-252CH N CH O CH.sub.3 CH.sub.3 H L-1gCH N CH O CH.sub.3 CH.sub.3 H L-1hCH N CH O CH.sub.3 CH.sub.3 H L-1iCH N CH O CH.sub.3 CH.sub.3 H L-1jCH N CH O CH.sub.3 CH.sub.3 H L-1k 208-209CH N CH O CH.sub.3 CH.sub.3 H L-1l 230-233CH N CH O CH.sub.3 CH.sub.3 H L-1m 237-239CH N CH O CH.sub.3 CH.sub.3 H L-1n 171-172CH N CH O CH.sub.3 CH.sub.3 H L-1o 233-236CH N CH O CH.sub.3 CH.sub.3 H L-1p 238-240CH N CH O CH.sub.3 CH.sub.3 H L-1q 196-199CH N CH O CH.sub.3 CH.sub.3 H L-1r 304-306CH N CH O CH.sub.3 CH.sub.3 H L-1s 232-234CH N CH O CH.sub.3 CH.sub.3 H L-1t 140-144CH N CH O CH.sub.3 CH.sub.3 H L-1uCH N CH O CH.sub.3 CH.sub.3 H L-1vCH N CH O CH.sub.3 CH.sub.3 H L-3aCH N CH O CH.sub.3 CH.sub.3 H L-3bCH N CH O CH.sub.3 CH.sub.3 H L-4aCH N CH O CH.sub.3 CH.sub.3 H L-7aCH N CH O CH.sub.3 CH.sub.3 H L-8a 203-205CH N CH O CH.sub.3 CH.sub.3 H L-8bCH N CH O CH.sub.3 CH.sub.3 H L-9aCH N CH O CH.sub.3 CH.sub.3 H L-10a 169-173CH N CH O CH.sub.3 CH.sub.3 H L-12aCH N CH O C(CH.sub.3).sub.3 CH.sub.3 H L-1a 124-125CH N CH O Cl CH.sub.3 H L-1d 257-259CH N CH O Cl CH H L-1e 192-198*CH N CH O CH.sub.3 CH.sub.3 H L-12bCH N CH O CH.sub.3 CH.sub.3 H L-12c 230-234CH N CH O CH.sub.3 CH.sub.3 H L-14aCH N CH O CH.sub.3 CH.sub.3 H L-15aCH N CH O CH.sub.3 CH.sub.3 H L-16a 260-262CH N CH O CH.sub.3 CH.sub.3 H L-16bCH N CH O CH.sub.3 CH.sub.3 H L-18aCH N CH O CH.sub.3 CH.sub.3 H L-20aCH N CH O CH.sub.3 CH.sub.3 H L-20b 192-196CH N CH O CH.sub.3 CH.sub.3 H L-20c 210-214CH N CH O CH.sub.3 CH.sub.3 H L-22aCH N CH S CH.sub.3 CH.sub.3 H L-1aCH N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH O OCH.sub.3 CH.sub.3 H L-1a 184-187CH N CH O OCH.sub.3 CH.sub.3 H L-1b 145-148CH N CH O OCH.sub.3 CH.sub.3 H L-1cCH N CH O OCH.sub.3 CH.sub.3 H L-1d 190-192CH N CH O OCH.sub.3 CH.sub.3 H L-1eCH N CH O OCH.sub.3 CH.sub.3 H L-1fCH N CH O OCH.sub.3 CH.sub.3 H L-1gCH N CH O OCH.sub.3 CH.sub.3 H L-1hCH N CH O OCH.sub.3 CH.sub.3 H L-1iCH N CH O OCH.sub.3 CH.sub.3 H L-1jCH N CH O OCH.sub.3 CH.sub.3 H L-1kCH N CH O OCH.sub.3 CH.sub.3 H L-1n 181-182(dec)CH N CH O OCH.sub.3 CH.sub.3 H L-3aCH N CH O OCH.sub.3 CH.sub.3 H L-3bCH N CH O OCH.sub.3 CH.sub.3 H L-4aCH N CH O OCH.sub.3 CH.sub.3 H L-7aCH N CH O OCH.sub.3 CH.sub.3 H L-8aCH N CH O OCH.sub.3 CH.sub.3 H L-8bCH N CH O OCH.sub.3 CH.sub.3 H L-9aCH N CH O OCH.sub.3 CH.sub.3 H L-12aCH N CH O OCH.sub.3 CH.sub.3 H L-12bCH N CH O OCH.sub.3 CH.sub.3 H L-14aCH N CH O OCH.sub.3 CH.sub.3 H L-15aCH N CH O OCH.sub.3 CH.sub.3 H L-16aCH N CH O OCH.sub.3 CH.sub.3 H L-16bCH N CH O OCH.sub.3 CH.sub.3 H L-18aCH N CH O OCH.sub.3 CH.sub.3 H L-20aCH N CH O OCH.sub.3 CH.sub.3 H L-22aCH N CH S OCH.sub.3 CH.sub.3 H L-1aCH N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH O CH.sub.3 OCH.sub.3 H L-1aCH N CH O OCH.sub.3 OCH.sub.3 H L-1b 186-190CH N CH O CH.sub.3 OCH.sub.3 H L-1cCH N CH O CH.sub.3 OCH.sub.3 H L-1dCH N CH O CH.sub.3 OCH.sub.3 H L-1eCH N CH O CH.sub.3 OCH.sub.3 H L-1fCH N CH O CH.sub.3 OCH.sub.3 H L-1gCH N CH O CH.sub.3 OCH.sub.3 H L-1hCH N CH O CH.sub.3 OCH.sub.3 H L-1iCH N CH O CH.sub.3 OCH.sub.3 H L-1jCH N CH O CH.sub.3 OCH.sub.3 H L-1kCH N CH O CH.sub.3 OCH.sub.3 H L-3aCH N CH O CH.sub.3 OCH.sub.3 H L-3bCH N CH O CH.sub.3 OCH.sub.3 H L-4aCH N CH O CH.sub.3 OCH.sub.3 H L-7aCH N CH O CH.sub.3 OCH.sub.3 H L-8aCH N CH O CH.sub.3 OCH.sub.3 H L-8bCH N CH O CH.sub.3 OCH.sub.3 H L-9aCH N CH O CH.sub.3 OCH.sub.3 H L-12aCH N CH O CH.sub.3 OCH.sub.3 H L-12bCH N CH O CH.sub.3 OCH.sub.3 H L-14aCH N CH O CH.sub.3 OCH.sub.3 H L-15aCH N CH O CH.sub.3 OCH.sub.3 H L-16aCH N CH O CH.sub.3 OCH.sub.3 H L-16bCH N CH O CH.sub.3 OCH.sub.3 H L-18aCH N CH O CH.sub.3 OCH.sub.3 H L-20aCH N CH O CH.sub.3 OCH.sub.3 H L-22aCH N CH S CH.sub.3 OCH.sub.3 H L-1aCH N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N CH O H CH.sub.3 H L-1aCH N CH O H CH.sub.3 H L-1b 236-237CH N CH O H CH.sub.3 H L-1c 249-251CH N CH O H CH.sub.3 H L-1d 240-243CH N CH O H CH.sub.3 H L-1eCH N CH O H CH.sub.3 H L-1fCH N CH O H CH.sub.3 H L-1gCH N CH O H CH.sub.3 H L-1hCH N CH O H CH.sub.3 H L-1iCH N CH O H CH.sub.3 H L-1jCH N CH O H CH.sub.3 H L-1kCH N CH O H CH.sub.3 H L-1l 293-294CH N CH O H CH.sub.3 H L-1mCH N CH O H CH.sub.3 H L-1n 145-150CH N CH O H CH.sub.3 H L-1oCH N CH O H CH.sub.3 H L-1pCH N CH O H CH.sub.3 H L-1qCH N CH O H CH.sub.3 H L-1rCH N CH O H CH.sub.3 H L-1sCH N CH O H CH.sub.3 H L-1tCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1a 247-250CH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1b 235-239CH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1c 285-286CH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1d 276-278CH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1eCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1fCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1gCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1hCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1iCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1jCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1kCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1l 270-271CH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1mCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1nCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1oCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1pCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1qCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1rCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1sCH N CH O N(CH.sub.3).sub.2 CH.sub.3 H L-1tCH CH N O CH.sub.3 CH.sub.3 H L-1a 228-230CH CH N O CH.sub.3 CH.sub.3 H L-1b 264-266CH CH N O CH.sub.3 CH.sub.3 H L-1c 257-258CH CH N O CH.sub.3 CH.sub.3 H L-1d 288-290CH CH N O CH.sub.3 CH.sub.3 H L-1eCH CH N O CH.sub.3 CH.sub.3 H L-1f 277-280CH CH N O CH.sub.3 CH.sub.3 H L-1gCH CH N O CH.sub.3 CH.sub.3 H L-1hCH CH N O CH.sub.3 CH.sub.3 H L-1iCH CH N O CH.sub.3 CH.sub.3 H L-1jCH CH N O CH.sub.3 CH.sub.3 H L-1k 258-260CH CH N O CH.sub.3 CH.sub.3 H L-1l 231-233CH CH N O CH.sub.3 CH.sub.3 H L-1mCH CH N O CH.sub.3 CH.sub.3 H L-1n 228-232CH CH N O CH.sub.3 CH.sub.3 H L-1o 283-284CH CH N O CH.sub.3 CH.sub.3 H L-1p 270-274CH CH N O CH.sub.3 CH.sub.3 H L-1q 262-264CH CH N O CH.sub.3 CH.sub.3 H L-1r 248-250CH CH N O CH.sub.3 CH.sub.3 H L-1sCH CH N O CH.sub.3 CH.sub.3 H L-1tCH CH N O CH.sub.3 CH.sub.3 H L-1u 270-272CH CH N O CH.sub.3 CH.sub.3 H L-1v 253-258CH CH N O CH.sub.3 CH.sub.3 H L-3aCH CH N O CH.sub.3 CH.sub.3 H L-3bCH CH N O CH.sub.3 CH.sub.3 H L-4aCH CH N O CH.sub.3 CH.sub.3 H L-7a 233-234CH CH N O CH.sub.3 CH.sub.3 H L-8aCH CH N O CH.sub.3 CH.sub.3 H L-8bCH CH N O CH.sub.3 CH.sub.3 H L-9aCH CH N O CH.sub.3 CH.sub.3 H L-10aCH CH N O CH.sub.3 CH.sub.3 H L-12aCH CH N O CH.sub.3 CH.sub.3 H L-12bCH CH N O CH.sub.3 CH.sub.3 H L-12cCH CH N O CH.sub.3 CH.sub.3 H L-14aCH CH N O CH.sub.3 CH.sub.3 H L-15aCH CH N O CH.sub.3 CH.sub.3 H L-16a 301-303CH CH N O CH.sub.3 CH.sub.3 H L-16bCH CH N O CH.sub.3 CH.sub.3 H L-18aCH CH N O CH.sub.3 CH.sub.3 H L-20aCH CH N O CH.sub.3 CH.sub.3 H L-20bCH CH N O CH.sub.3 CH.sub.3 H L-20cCH CH N O CH.sub.3 CH.sub.3 H L-22aCH CH N S CH.sub.3 CH.sub.3 H L-1aCH CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N O OCH.sub.3 CH.sub.3 H L-1aCH CH N O OCH.sub.3 CH.sub.3 H L-1bCH CH N O OCH.sub.3 CH.sub.3 H L-1cCH CH N O OCH.sub.3 CH.sub.3 H L-1dCH CH N O OCH.sub.3 CH.sub.3 H L-1eCH CH N O OCH.sub.3 CH.sub.3 H L-1fCH CH N O OCH.sub.3 CH.sub.3 H L-1gCH CH N O OCH.sub.3 CH.sub.3 H L-1hCH CH N O OCH.sub.3 CH.sub.3 H L-1iCH CH N O OCH.sub.3 CH.sub.3 H L-1jCH CH N O OCH.sub.3 CH.sub.3 H L-1kCH CH N O OCH.sub.3 CH.sub.3 H L-3aCH CH N O OCH.sub.3 CH.sub. 3 H L-3bCH CH N O OCH.sub.3 CH.sub.3 H L-4aCH CH N O OCH.sub.3 CH.sub.3 H L-7aCH CH N O OCH.sub.3 CH.sub.3 H L-8aCH CH N O OCH.sub.3 CH.sub.3 H L-8bCH CH N O OCH.sub.3 CH.sub.3 H L-9aCH CH N O OCH.sub.3 CH.sub.3 H L-12aCH CH N O OCH.sub.3 CH.sub.3 H L-12bCH CH N O OCH.sub.3 CH.sub.3 H L-14aCH CH N O OCH.sub.3 CH.sub.3 H L-15aCH CH N O OCH.sub.3 CH.sub.3 H L-16aCH CH N O OCH.sub.3 CH.sub.3 H L-16bCH CH N O OCH.sub.3 CH.sub.3 H L-18aCH CH N O OCH.sub.3 CH.sub.3 H L-20aCH CH N O OCH.sub.3 CH.sub.3 H L-22aCH CH N S OCH.sub.3 CH.sub.3 H L-1aCH CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N O CH.sub.3 OCH.sub.3 H L-1aCH CH N O CH.sub.3 OCH.sub.3 H L-1bCH CH N O CH.sub.3 OCH.sub.3 H L-1cCH CH N O CH.sub.3 OCH.sub.3 H L-1dCH CH N O CH.sub.3 OCH.sub.3 H L-1eCH CH N O CH.sub.3 OCH.sub.3 H L-1fCH CH N O CH.sub.3 OCH.sub.3 H L-1gCH CH N O CH.sub.3 OCH.sub.3 H L-1hCH CH N O CH.sub.3 OCH.sub.3 H L-1iCH CH N O CH.sub.3 OCH.sub.3 H L-1jCH CH N O CH.sub.3 OCH.sub.3 H L-1kCH CH N O CH.sub.3 OCH.sub.3 H L-3aCH CH N O CH.sub.3 OCH.sub.3 H L-3bCH CH N O CH.sub.3 OCH.sub.3 H L-4aCH CH N O CH.sub.3 OCH.sub.3 H L-7aCH CH N O CH.sub.3 OCH.sub.3 H L-8aCH CH N O CH.sub.3 OCH.sub.3 H L-8bCH CH N O CH.sub.3 OCH.sub.3 H L-9aCH CH N O CH.sub.3 OCH.sub.3 H L-12aCH CH N O CH.sub.3 OCH.sub.3 H L-12bCH CH N O CH.sub.3 OCH.sub.3 H L-14aCH CH N O CH.sub.3 OCH.sub.3 H L-15aCH CH N O CH.sub.3 OCH.sub.3 H L-16aCH CH N O CH.sub.3 OCH.sub.3 H L-16bCH CH N O CH.sub.3 OCH.sub.3 H L-18aCH CH N O CH.sub.3 OCH.sub.3 H L-20aCH CH N O CH.sub.3 OCH.sub.3 H L-22aCH CH N S CH.sub.3 OCH.sub.3 H L-1aCH CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N O OCH.sub.3 OCH.sub.3 H L-1aCH CH N O OCH.sub.3 OCH.sub.3 H L-1bCH CH N O OCH.sub.3 OCH.sub.3 H L-1cCH CH N O OCH.sub.3 OCH.sub.3 H L-1dCH CH N O OCH.sub.3 OCH.sub.3 H L-1eCH CH N O OCH.sub.3 OCH.sub.3 H L-1fCH CH N O OCH.sub.3 OCH.sub.3 H L-1gCH CH N O OCH.sub.3 OCH.sub.3 H L-1hCH CH N O OCH.sub.3 OCH.sub.3 H L-1iCH CH N O OCH.sub.3 OCH.sub.3 H L-1jCH CH N O OCH.sub.3 OCH.sub.3 H L-1kCH CH N O OCH.sub.3 OCH.sub.3 H L-3aCH CH N O OCH.sub.3 OCH.sub.3 H L-3bCH CH N O OCH.sub.3 OCH.sub.3 H L-4aCH CH N O OCH.sub. 3 OCH.sub.3 H L-7aCH CH N O OCH.sub.3 OCH.sub.3 H L-8aCH CH N O OCH.sub.3 OCH.sub.3 H L-8bCH CH N O OCH.sub.3 OCH.sub.3 H L-9aCH CH N O OCH.sub.3 OCH.sub.3 H L-12aCH CH N O OCH.sub.3 OCH.sub.3 H L-12bCH CH N O OCH.sub.3 OCH.sub.3 H L-14aCH CH N O OCH.sub.3 OCH.sub.3 H L-15aCH CH N O OCH.sub.3 OCH.sub.3 H L-16aCH CH N O OCH.sub.3 OCH.sub.3 H L-16bCH CH N O OCH.sub.3 OCH.sub.3 H L-18aCH CH N O OCH.sub.3 OCH.sub.3 H L-20aCH CH N O OCH.sub.3 OCH.sub.3 H L-22aCH CH N S OCH.sub.3 OCH.sub.3 H L-1aCH CH N S OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N N O CH.sub.3 CH.sub.3 H L-1a 193-195CH N N O CH.sub.3 CH.sub.3 H L-1b 223-225CH N N O CH.sub.3 CH.sub.3 H L-1c 172-176CH N N O CH.sub.3 CH.sub.3 H L-1d 239-242CH N N O CH.sub.3 CH.sub.3 H L-1eCH N N O CH.sub.3 CH.sub.3 H L-1f 155-157(d)CH N N O CH.sub.3 CH.sub.3 H L-1gCH N N O CH.sub.3 CH.sub.3 H L-1hCH N N O CH.sub.3 CH.sub.3 H L-1iCH N N O CH.sub.3 CH.sub.3 H L-1jCH N N O CH.sub.3 CH.sub.3 H L-1k 151-153CH N N O CH.sub.3 CH.sub.3 H L-1l 222-225CH N N O CH.sub.3 CH.sub.3 H L-1mCH N N O CH.sub.3 CH.sub.3 H L-1n 170-174CH N N O CH.sub.3 CH.sub.3 H L-1o 197-198CH N N O CH.sub.3 CH.sub.3 H L-1p 211-213CH N N O CH.sub.3 CH.sub.3 H L-1q 178-180CH N N O CH.sub.3 CH.sub.3 H L-1rCH N N O CH.sub.3 CH.sub.3 H L-1s 215-216CH N N O CH.sub.3 CH.sub.3 H L-1t 149-153CH N N O CH.sub.3 CH.sub.3 H L-1uCH N N O CH.sub.3 CH.sub.3 H L-1vCH N N O CH.sub.3 CH.sub.3 H L-1w 152-154CH N N O CH.sub.3 CH.sub.3 H L-3a 163-164(d)CH N N O CH.sub.3 CH.sub.3 H L-3b 116-118CH N N O CH.sub.3 CH.sub.3 H L-4aCH N N O CH.sub.3 CH.sub.3 H L-7aCH N N O CH.sub.3 CH.sub.3 H L-8aCH N N O CH.sub.3 CH.sub.3 H L-8bCH N N O CH.sub.3 CH.sub.3 H L-9aCH N N O CH.sub.3 CH.sub.3 H L-25a 183-186CH N N O CH.sub.3 CH.sub.3 H L-1ae 178-180CH N N O CH.sub.3 CH.sub.3 H L-1ad 255-256(d)CH N N O CH.sub.3 CH.sub.3 H L-1af 124-125(d)CH N N O CH.sub.3 CH.sub.3 H L-10aCH N N O CH.sub.3 CH.sub.3 H L-12aCH N N O CH.sub.3 CH.sub.3 H L-12bCH N N O CH.sub.3 CH.sub.3 H L-12cCH N N O CH.sub.3 CH.sub.3 H L-14aCH N N O CH.sub.3 CH.sub.3 H L-15aCH N N O CH.sub.3 CH.sub.3 H L-16a 237-238CH N N O CH.sub.3 CH.sub.3 H L-16bCH N N O CH.sub.3 CH.sub.3 H L-18aCH N N O CH.sub.3 CH.sub.3 H L-20aCH N N O CH.sub.3 CH.sub.3 H L-20bCH N N O CH.sub.3 CH.sub.3 H L-20cCH N N O CH.sub.3 CH.sub.3 H L-22aCH N N S CH.sub.3 CH.sub.3 H L-1aCH N N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N N O OCH.sub.3 CH.sub.3 H L-1aCH N N O OCH.sub.3 CH.sub.3 H L-1bCH N N O OCH.sub.3 CH.sub.3 H L-1cCH N N O OCH.sub.3 CH.sub.3 H L-1dCH N N O OCH.sub.3 CH.sub.3 H L-1eCH N N O OCH.sub.3 CH.sub.3 H L-1fCH N N O OCH.sub.3 CH.sub.3 H L-1gCH N N O OCH.sub.3 CH.sub.3 H L-1hCH N N O OCH.sub.3 CH.sub.3 H L-liCH N N O OCH.sub.3 CH.sub.3 H L-1jCH N N O OCH.sub.3 CH.sub.3 H L-lkCH N N O OCH.sub.3 CH.sub.3 H L-3aCH N N O OCH.sub.3 CH.sub.3 H L-3bCH N N O OCH.sub.3 CH.sub.3 H L-4aCH N N O OCH.sub.3 CH.sub.3 H L-7aCH N N O OCH.sub.3 CH.sub.3 H L-8aCH N N O OCH.sub.3 CH.sub.3 H L-8bCH N N O OCH.sub.3 CH.sub.3 H L-9aCH N N O OCH.sub.3 CH.sub.3 H L-12aCH N N O OCH.sub.3 CH.sub.3 H L-12bCH N N O OCH.sub.3 CH.sub.3 H L-14aCH N N O OCH.sub.3 CH.sub.3 H L-15aCH N N O OCH.sub.3 CH.sub.3 H L-16aCH N N O OCH.sub.3 CH.sub.3 H L-16bCH N N O OCH.sub.3 CH.sub.3 H L-18aCH N N O OCH.sub.3 CH.sub.3 H L-20aCH N N O OCH.sub.3 CH.sub.3 H L-22aCH N N S OCH.sub.3 CH.sub.3 H L-1aCH N N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N N O CH.sub.3 OCH.sub.3 H L-1aCH N N O CH.sub.3 OCH.sub.3 H L-1bCH N N O CH.sub.3 OCH.sub.3 H L-1cCH N N O CH.sub.3 OCH.sub.3 H L-1dCH N N O CH.sub.3 OCH.sub.3 H L-1eCH N N O CH.sub.3 OCH.sub.3 H L-1fCH N N O CH.sub.3 OCH.sub.3 H L-1gCH N N O CH.sub.3 OCH.sub.3 H L-1hCH N N O CH.sub.3 OCH.sub.3 H L-liCH N N O CH.sub.3 OCH.sub.3 H L-1jCH N N O CH.sub.3 OCH.sub.3 H L-lkCH N N O CH.sub.3 OCH.sub.3 H L-3aCH N N O CH.sub.3 OCH.sub.3 H L-3bCH N N O CH.sub.3 OCH.sub.3 H L-4aCH N N O CH.sub.3 OCH.sub.3 H L-7aCH N N O CH.sub.3 OCH.sub.3 H L-8aCH N N O CH.sub.3 OCH.sub.3 H L-8bCH N N O CH.sub.3 OCH.sub.3 H L-9aCH N N O CH.sub.3 OCH.sub.3 H L-12aCH N N O CH.sub.3 OCH.sub.3 H L-12bCH N N O CH.sub.3 OCH.sub.3 H L-14aCH N N O CH.sub.3 OCH.sub.3 H L-15aCH N N O CH.sub.3 OCH.sub.3 H L-16aCH N N O CH.sub.3 OCH.sub.3 H L-16bCH N N O CH.sub.3 OCH.sub.3 H L-18aCH N N O CH.sub.3 OCH.sub.3 H L-20aCH N N O CH.sub.3 OCH.sub.3 H L-22aCH N N S CH.sub.3 OCH.sub.3 H L-1aCH N N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N N O OCH.sub.3 OCH.sub.3 H L-1aCH N N O OCH.sub.3 OCH.sub.3 H L-1bCH N N O OCH.sub.3 OCH.sub.3 H L-1cCH N N O OCH.sub.3 OCH.sub.3 H L-1dCH N N O OCH.sub.3 OCH.sub.3 H L-1eCH N N O OCH.sub.3 OCH.sub.3 H L-1fCH N N O OCH.sub.3 OCH.sub.3 H L-1gCH N N O OCH.sub.3 OCH.sub.3 H L-1hCH N N O OCH.sub.3 OCH.sub.3 H L-liCH N N O OCH.sub.3 OCH.sub.3 H L-1jCH N N O OCH.sub.3 OCH.sub.3 H L-lkCH N N O OCH.sub.3 OCH.sub.3 H L-3aCH N N O OCH.sub.3 OCH.sub.3 H L-3bCH N N O OCH.sub.3 OCH.sub.3 H L-4aCH N N O OCH.sub.3 OCH.sub.3 H L-7aCH N N O OCH.sub.3 OCH.sub.3 H L-8aCH N N O OCH.sub.3 OCH.sub.3 H L-8bCH N N O OCH.sub.3 OCH.sub.3 H L-9aCH N N O OCH.sub.3 OCH.sub.3 H L-12aCH N N O OCH.sub.3 OCH.sub.3 H L-12bCH N N O OCH.sub.3 OCH.sub.3 H L-14aCH N N O OCH.sub.3 OCH.sub.3 H L-15aCH N N O OCH.sub.3 OCH.sub.3 H L-16aCH N N O OCH.sub.3 OCH.sub.3 H L-16bCH N N O OCH.sub.3 OCH.sub.3 H L-18aCH N N O OCH.sub.3 OCH.sub.3 H L-20aCH N N O OCH.sub.3 OCH.sub.3 H L-22aCH N N S OCH.sub.3 OCH.sub.3 H L-1aCH N N S OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH O OCH.sub.3 OCH.sub.3 H L-1aCH CH CH O OCH.sub.3 OCH.sub.3 H L-1bCH CH CH O OCH.sub.3 OCH.sub.3 H L-1cCH CH CH O OCH.sub.3 OCH.sub.3 H L-1dCH CH CH O OCH.sub.3 OCH.sub.3 H L-1eCH CH CH O OCH.sub.3 OCH.sub.3 H L-1fCH CH CH O OCH.sub.3 OCH.sub.3 H L-1gCH CH CH O OCH.sub.3 OCH.sub.3 H L-1hCH CH CH O OCH.sub.3 OCH.sub.3 H L-liCH CH CH O OCH.sub.3 OCH.sub.3 H L-1jCH CH CH O OCH.sub.3 OCH.sub.3 H L-lkCH CH CH O OCH.sub.3 OCH.sub.3 H L-3aCH CH CH O OCH.sub.3 OCH.sub.3 H L-3bCH CH CH O OCH.sub.3 OCH.sub.3 H L-4aCH CH CH O OCH.sub.3 OCH.sub.3 H L-7aCH CH CH O OCH.sub.3 OCH.sub.3 H L-8aCH CH CH O OCH.sub.3 OCH.sub.3 H L-8bCH CH CH O OCH.sub.3 OCH.sub.3 H L-9aCH CH CH O OCH.sub.3 OCH.sub.3 H L-12aCH CH CH O OCH.sub.3 OCH.sub.3 H L-12bCH CH CH O OCH.sub.3 OCH.sub.3 H L-14aCH CH CH O OCH.sub.3 OCH.sub.3 H L-15aCH CH CH O OCH.sub.3 OCH.sub.3 H L-16aCH CH CH O OCH.sub.3 OCH.sub.3 H L-16bCH CH CH O OCH.sub.3 OCH.sub.3 H L-18aCH CH CH O OCH.sub.3 OCH.sub.3 H L-20aCH CH CH O OCH.sub.3 OCH.sub.3 H L-22aCH CH CH S OCH.sub.3 OCH.sub.3 H L-1aCH CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH O CH.sub.3 CH.sub.3 H L-1aCH CH CH O CH.sub.3 CH.sub.3 H L-1bCH CH CH O CH.sub.3 CH.sub.3 H L-1cCH CH CH O CH.sub.3 CH.sub.3 H L-1dCH CH CH O CH.sub.3 CH.sub.3 H L-1eCH CH CH O CH.sub.3 CH.sub.3 H L-1fCH CH CH O CH.sub.3 CH.sub.3 H L-1gCH CH CH O CH.sub.3 CH.sub.3 H L-1hCH CH CH O CH.sub.3 CH.sub.3 H L-liCH CH CH O CH.sub.3 CH.sub.3 H L-1jCH CH CH O CH.sub.3 CH.sub.3 H L-lkCH CH CH O CH.sub.3 CH.sub.3 H L-3aCH CH CH O CH.sub.3 CH.sub.3 H L-3bCH CH CH O CH.sub.3 CH.sub.3 H L-4aCH CH CH O CH.sub.3 CH.sub.3 H L-7aCH CH CH O CH.sub.3 CH.sub. 3 H L-8aCH CH CH O CH.sub.3 CH.sub.3 H L-8bCH CH CH O CH.sub.3 CH.sub.3 H L-9aCH CH CH O CH.sub.3 CH.sub.3 H L-12aCH CH CH O CH.sub.3 CH.sub.3 H L-12bCH CH CH O CH.sub.3 CH.sub.3 H L-14aCH CH CH O CH.sub.3 CH.sub.3 H L-15aCH CH CH O CH.sub.3 CH.sub.3 H L-16aCH CH CH O CH.sub.3 CH.sub.3 H L-16bCH CH CH O CH.sub.3 CH.sub.3 H L-18aCH CH CH O CH.sub.3 CH.sub.3 H L-20aCH CH CH O CH.sub.3 CH.sub.3 H L-22aCH CH CH S CH.sub.3 CH.sub.3 H L-1aCH CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH O OCH.sub.3 CH.sub.3 H L-1aCH CH CH O OCH.sub.3 CH.sub.3 H L-1bCH CH CH O OCH.sub.3 CH.sub.3 H L-1cCH CH CH O OCH.sub.3 CH.sub.3 H L-1dCH CH CH O OCH.sub.3 CH.sub.3 H L-1eCH CH CH O OCH.sub.3 CH.sub.3 H L-1fCH CH CH O OCH.sub.3 CH.sub.3 H L-1gCH CH CH O OCH.sub.3 CH.sub.3 H L-LhCH CH CH O OCH.sub.3 CH.sub.3 H L-liCH CH CH O OCH.sub.3 CH.sub.3 H L-1jCH CH CH O OCH.sub.3 CH.sub.3 H L-lkCH CH CH O OCH.sub.3 CH.sub.3 H L-3aCH CH CH O OCH.sub.3 CH.sub.3 H L-3bCH CH CH O OCH.sub.3 CH.sub.3 H L-4aCH CH CH O OCH.sub.3 CH.sub.3 H L-7aCH CH CH O OCH.sub.3 CH.sub.3 H L-8aCH CH CH O OCH.sub.3 CH.sub.3 H L-8bCH CH CH O OCH.sub.3 CH.sub.3 H L-9aCH CH CH O OCH.sub.3 CH.sub.3 H L-12aCH CH CH O OCH.sub.3 CH.sub.3 H L-12bCH CH CH O OCH.sub.3 CH.sub.3 H L-14aCH CH CH O OCH.sub.3 CH.sub.3 H L-15aCH CH CH O OCH.sub.3 CH.sub.3 H L-16aCH CH CH O OCH.sub.3 CH.sub.3 H L-16bCH CH CH O OCH.sub.3 CH.sub.3 H L-18aCH CH CH O OCH.sub.3 CH.sub.3 H L-20aCH CH CH O OCH.sub.3 CH.sub.3 H L-22aCH CH CH S OCH.sub.3 CH.sub.3 H L-1aCH CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH O CH.sub.3 OCH.sub.3 H L-1aCH CH CH O CH.sub.3 OCH.sub.3 H L-1bCH CH CH O CH.sub.3 OCH.sub.3 H L-1cCH CH CH O CH.sub.3 OCH.sub.3 H L-1dCH CH CH O CH.sub.3 OCH.sub.3 H L-1eCH CH CH O CH.sub.3 OCH.sub.3 H L-1fCH CH CH O CH.sub.3 OCH.sub.3 H L-1gCH CH CH O CH.sub.3 OCH.sub.3 H L-1hCH CH CH O CH.sub.3 OCH.sub.3 H L-liCH CH CH O CH.sub.3 OCH.sub.3 H L-1jCH CH CH O CH.sub.3 OCH.sub.3 H L-lkCH CH CH O CH.sub.3 OCH.sub.3 H L-3aCH CH CH O CH.sub.3 OCH.sub.3 H L-3bCH CH CH O CH.sub.3 OCH.sub.3 H L-4aCH CH CH O CH.sub.3 OCH.sub.3 H L-7aCH CH CH O CH.sub.3 OCH.sub.3 H L-8aCH CH CH O CH.sub.3 OCH.sub.3 H L-8bCH CH CH O CH.sub. 3 OCH.sub.3 H L-9aCH CH CH O CH.sub.3 OCH.sub.3 H L-12aCH CH CH O CH.sub.3 OCH.sub.3 H L-12bCH CH CH O CH.sub.3 OCH.sub.3 H L-14aCH CH CH O CH.sub.3 OCH.sub.3 H L-15aCH CH CH O CH.sub.3 OCH.sub.3 H L-16aCH CH CH O CH.sub.3 OCH.sub.3 H L-16bCH CH CH O CH.sub.3 OCH.sub.3 H L-18aCH CH CH O CH.sub.3 OCH.sub.3 H L-20aCH CH CH O CH.sub.3 OCH.sub.3 H L-22aCH CH CH S CH.sub.3 OCH.sub.3 H L-1aCH CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH O OCH.sub.3 OCH.sub.3 H L-1aCH CH CH O OCH.sub.3 OCH.sub.3 H L-1bCH CH CH O OCH.sub.3 OCH.sub.3 H L-1cCH CH CH O OCH.sub.3 OCH.sub.3 H L-1dCH CH CH O OCH.sub.3 OCH.sub.3 H L-1eCH CH CH O OCH.sub.3 OCH.sub.3 H L-1fCH CH CH O OCH.sub.3 OCH.sub.3 H L-1gCH CH CH O OCH.sub.3 OCH.sub.3 H L-1hCH CH CH O OCH.sub.3 OCH.sub.3 H L-1iCH CH CH O OCH.sub.3 OCH.sub.3 H L-1jCH CH CH O OCH.sub.3 OCH.sub.3 H L-1kCH CH CH O OCH.sub.3 OCH.sub.3 H L-3aCH CH CH O OCH.sub.3 OCH.sub.3 H L-3bCH CH CH O OCH.sub.3 OCH.sub.3 H L-4aCH CH CH O OCH.sub.3 OCH.sub.3 H L-7aCH CH CH O OCH.sub.3 OCH.sub.3 H L-8aCH CH CH O OCH.sub.3 OCH.sub.3 H L-8bCH CH CH O OCH.sub.3 OCH.sub.3 H L-9aCH CH CH O OCH.sub.3 OCH.sub.3 H L-12aCH CH CH O OCH.sub.3 OCH.sub.3 H L-12bCH CH CH O OCH.sub.3 OCH.sub.3 H L-14aCH CH CH O OCH.sub.3 OCH.sub.3 H L-15aCH CH CH O OCH.sub.3 OCH.sub.3 H L-16aCH CH CH O OCH.sub.3 OCH.sub.3 H L-16bCH CH CH O OCH.sub.3 OCH.sub.3 H L-18aCH CH CH O OCH.sub.3 OCH.sub.3 H L-20aCH CH CH O OCH.sub.3 OCH.sub.3 H L-22aCH CH CH S OCH.sub.3 OCH.sub.3 H L-1aCH CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH O CH.sub.3 CH.sub.3 H L-1aN N CH O CH.sub.3 CH.sub.3 H L-1bN N CH O CH.sub.3 CH.sub.3 H L-1cN N CH O CH.sub.3 CH.sub.3 H L-1dN N CH O CH.sub.3 CH.sub.3 H L-1eN N CH O CH.sub.3 CH.sub.3 H L-1fN N CH O CH.sub.3 CH.sub.3 H L-1gN N CH O CH.sub.3 CH.sub.3 H L-1hN N CH O CH.sub.3 CH.sub.3 H L-1iN N CH O CH.sub.3 CH.sub.3 H L-1jN N CH O CH.sub.3 CH.sub.3 H L-1kN N CH O CH.sub.3 CH.sub.3 H L-3aN N CH O CH.sub.3 CH.sub.3 H L-3bN N CH O CH.sub.3 CH.sub.3 H L-4aN N CH O CH.sub.3 CH.sub.3 H L-7aN N CH O CH.sub.3 CH.sub.3 H L-8aN N CH O CH.sub.3 CH.sub.3 H L-8bN N CH O CH.sub.3 CH.sub.3 H L-9aN N CH O CH.sub.3 CH.sub.3 H L-12aN N CH O CH.sub.3 CH.sub.3 H L-12bN N CH O CH.sub.3 CH.sub.3 H L-14aN N CH O CH.sub.3 CH.sub.3 H L-15aN N CH O CH.sub.3 CH.sub.3 H L-16aN N CH O CH.sub.3 CH.sub.3 H L-16bN N CH O CH.sub.3 CH.sub.3 H L-18aN N CH O CH.sub.3 CH.sub.3 H L-20aN N CH O CH.sub.3 CH.sub.3 H L-22aN N CH S CH.sub.3 CH.sub.3 H L-1aN N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH O CH.sub.3 CH.sub.3 H L-1z 185-203N N CH O CH.sub.3 CH.sub.3 H L-1y 193-211N N CH O CH.sub.3 CH.sub.3 H L-1aa 192-214N N CH O CH.sub.3 CH.sub.3 H L-1q 197-217N N CH O CH.sub.3 CH.sub.3 H L-1ab 189-198N N CH O OCH.sub.3 CH.sub.3 H L-1aN N CH O OCH.sub.3 CH.sub.3 H L-1bN N CH O OCH.sub.3 CH.sub.3 H L-1cN N CH O OCH.sub.3 CH.sub.3 H L-1dN N CH O OCH.sub.3 CH.sub.3 H L-1eN N CH O OCH.sub.3 CH.sub.3 H L-1fN N CH O OCH.sub.3 CH.sub.3 H L-1gN N CH O OCH.sub.3 CH.sub.3 H L-1hN N CH O OCH.sub.3 CH.sub.3 H L-1iN N CH O OCH.sub.3 CH.sub.3 H L-1jN N CH O OCH.sub.3 CH.sub.3 H L-1kN N CH O OCH.sub.3 CH.sub.3 H L-3aN N CH O OCH.sub.3 CH.sub.3 H L-3bN N CH O OCH.sub.3 CH.sub.3 H L-4aN N CH O OCH.sub.3 CH.sub.3 H L-7aN N CH O OCH.sub.3 CH.sub.3 H L-8aN N CH O OCH.sub.3 CH.sub.3 H L-8bN N CH O OCH.sub.3 CH.sub.3 H L-9aN N CH O OCH.sub.3 CH.sub.3 H L-12aN N CH O OCH.sub.3 CH.sub.3 H L-12bN N CH O OCH.sub.3 CH.sub.3 H L-14aN N CH O OCH.sub.3 CH.sub.3 H L-15aN N CH O OCH.sub.3 CH.sub.3 H L-16aN N CH O OCH.sub.3 CH.sub.3 H L-16bN N CH O OCH.sub.3 CH.sub.3 H L-18aN N CH O OCH.sub.3 CH.sub.3 H L-20aN N CH O OCH.sub.3 CH.sub.3 H L-22aN N CH S OCH.sub.3 CH.sub.3 H L-1aN N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH O CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 H L-1bN N CH O CH.sub.3 OCH.sub.3 H L-1cN N CH O CH.sub.3 OCH.sub.3 H L-1dN N CH O CH.sub.3 OCH.sub.3 H L-1eN N CH O CH.sub.3 OCH.sub.3 H L-1fN N CH O CH.sub.3 OCH.sub.3 H L-1gN N CH O CH.sub.3 OCH.sub.3 H L-1hN N CH O CH.sub.3 OCH.sub.3 H L-1iN N CH O CH.sub.3 OCH.sub.3 H L-1jN N CH O CH.sub.3 OCH.sub.3 H L-1kN N CH O CH.sub.3 OCH.sub.3 H L-3aN N CH O CH.sub.3 OCH.sub.3 H L-3bN N CH O CH.sub.3 OCH.sub.3 H L-4aN N CH O CH.sub.3 OCH.sub.3 H L-7aN N CH O CH.sub.3 OCH.sub.3 H L-8aN N CH O CH.sub.3 OCH.sub.3 H L-8bN N CH O CH.sub.3 OCH.sub.3 H L-9aN N CH O CH.sub.3 OCH.sub.3 H L-12aN N CH O CH.sub.3 OCH.sub.3 H L-12bN N CH O CH.sub.3 OCH.sub.3 H L-14aN N CH O CH.sub.3 OCH.sub.3 H L-15aN N CH O CH.sub.3 OCH.sub.3 H L-16aN N CH O CH.sub.3 OCH.sub.3 H L-16bN N CH O CH.sub.3 OCH.sub.3 H L-18aN N CH O CH.sub.3 OCH.sub.3 H L-20aN N CH O CH.sub.3 OCH.sub.3 H L-22aN N CH S CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH O OCH.sub.3 OCH.sub.3 H L-1a 122-157N N CH O OCH.sub.3 OCH.sub.3 H L-1b 237-248N N CH O OCH.sub.3 OCH.sub.3 H L-1c 239-244N N CH O OCH.sub.3 OCH.sub.3 H L-1d 207-236N N CH O OCH.sub.3 OCH.sub.3 H L-1eN N CH O OCH.sub.3 OCH.sub.3 H L-1fN N CH O OCH.sub.3 OCH.sub.3 H L-1gN N CH O OCH.sub.3 OCH.sub.3 H L-1hN N CH O OCH.sub.3 OCH.sub.3 H L-1iN N CH O OCH.sub.3 OCH.sub.3 H L-1jN N CH O OCH.sub.3 OCH.sub.3 H L-1kN N CH O OCH.sub.3 OCH.sub.3 H L-1e 239-261N N CH O OCH.sub.3 OCH.sub.3 H L-3aN N CH O OCH.sub.3 OCH.sub.3 H L-3bN N CH O OCH.sub.3 OCH.sub.3 H L-4aN N CH O OCH.sub.3 OCH.sub.3 H L-7aN N CH O OCH.sub.3 OCH.sub.3 H L-8aN N CH O OCH.sub.3 OCH.sub.3 H L-8bN N CH O OCH.sub.3 OCH.sub.3 H L-9aN N CH O OCH.sub.3 OCH.sub.3 H L-12aN N CH O OCH.sub.3 OCH.sub.3 H L-12bN N CH O OCH.sub.3 OCH.sub.3 H L-14aN N CH O OCH.sub.3 OCH.sub.3 H L-15aN N CH O OCH.sub.3 OCH.sub.3 H L-16aN N CH O OCH.sub.3 OCH.sub.3 H L-16bN N CH O OCH.sub.3 OCH.sub.3 H L-18aN N CH O OCH.sub.3 OCH.sub.3 H L-20aN N CH O OCH.sub.3 OCH.sub.3 H L-22aN N CH S OCH.sub.3 OCH.sub.3 H L-1aN N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH O OCH.sub.3 OCH.sub.3 H L-1t 114-137N N CH O OCH.sub.3 OCH.sub.3 H L-1y 220-231N N CH O OCH.sub.3 OCH.sub.3 H L-1z 246-253N N CH O OCH.sub.3 OCH.sub.3 H L-1aa 262-270N N CH O OCH.sub.3 OCH.sub.3 H L-1ab 228-244N N CH O OCH.sub.3 OCH.sub.3 H L-1ac 176-178N N CH O OCH.sub.3 OCH.sub.3 H L-1ad 192-238N N CH O CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 H L-1bN N CH O CH.sub.3 OCH.sub.3 H L-1cN N CH O CH.sub.3 OCH.sub.3 H L-1dN N CH O CH.sub.3 OCH.sub.3 H L-1eN N CH O CH.sub.3 OCH.sub.3 H L-1fN N CH O CH.sub. 3 OCH.sub.3 H L-1gN N CH O CH.sub.3 OCH.sub.3 H L-1hN N CH O CH.sub.3 OCH.sub.3 H L-1iN N CH O CH.sub.3 OCH.sub.3 H L-1jN N CH O CH.sub.3 OCH.sub.3 H L-1kN N CH O CH.sub.3 OCH.sub.3 H L-3aN N CH O CH.sub.3 OCH.sub.3 H L-3bN N CH O CH.sub.3 OCH.sub.3 H L-4aN N CH O CH.sub.3 OCH.sub.3 H L-7aN N CH O CH.sub.3 OCH.sub.3 H L-8aN N CH O CH.sub.3 OCH.sub.3 H L-8bN N CH O CH.sub.3 OCH.sub.3 H L-9aN N CH O CH.sub.3 OCH.sub.3 H L-12aN N CH O CH.sub.3 OCH.sub.3 H L-12bN N CH O CH.sub.3 OCH.sub.3 H L-14aN N CH O CH.sub.3 OCH.sub.3 H L-15aN N CH O CH.sub.3 OCH.sub.3 H L-16aN N CH O CH.sub.3 OCH.sub.3 H L-16bN N CH O CH.sub.3 OCH.sub.3 H L-18aN N CH O CH.sub.3 OCH.sub.3 H L-20aN N CH O CH.sub. 3 OCH.sub.3 H L-22aN N CH S CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH O OCH.sub.3 OCH.sub.3 H L-1aN N CH O OCH.sub.3 OCH.sub.3 H L-1bN N CH O OCH.sub.3 OCH.sub.3 H L-1cN N CH O OCH.sub.3 OCH.sub.3 H L-1dN N CH O OCH.sub.3 OCH.sub.3 H L-1eN N CH O OCH.sub.3 OCH.sub.3 H L-1fN N CH O OCH.sub.3 OCH.sub.3 H L-1gN N CH O OCH.sub.3 OCH.sub.3 H L-1hN N CH O OCH.sub.3 OCH.sub.3 H L-1iN N CH O OCH.sub.3 OCH.sub.3 H L-1jN N CH O OCH.sub.3 OCH.sub.3 H L-1kN N CH O OCH.sub.3 OCH.sub.3 H L-3aN N CH O OCH.sub.3 OCH.sub.3 H L-3bN N CH O OCH.sub.3 OCH.sub.3 H L-4aN N CH O OCH.sub.3 OCH.sub.3 H L-7aN N CH O OCH.sub.3 OCH.sub.3 H L-8aN N CH O OCH.sub.3 OCH.sub.3 H L-8bN N CH O OCH.sub.3 OCH.sub.3 H L-9aN N CH O OCH.sub.3 OCH.sub.3 H L-12aN N CH O OCH.sub.3 OCH.sub.3 H L-12bN N CH O OCH.sub.3 OCH.sub.3 H L-14aN N CH O OCH.sub.3 OCH.sub.3 H L-15aN N CH O OCH.sub.3 OCH.sub.3 H L-16aN N CH O OCH.sub.3 OCH.sub.3 H L-16bN N CH O OCH.sub.3 OCH.sub.3 H L-18aN N CH O OCH.sub.3 OCH.sub.3 H L-20aN N CH O OCH.sub.3 OCH.sub.3 H L-22aN N CH S OCH.sub.3 OCH.sub.3 H L-1aN N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N N O CH.sub.3 CH.sub.3 H L-1aN N N O CH.sub.3 CH.sub.3 H L-1bN N N O CH.sub.3 CH.sub.3 H L-1cN N N O CH.sub.3 CH.sub.3 H L-1dN N N O CH.sub.3 CH.sub.3 H L-1eN N N O CH.sub.3 CH.sub.3 H L-1fN N N O CH.sub.3 CH.sub.3 H L-1gN N N O CH.sub.3 CH.sub.3 H L-1hN N N O CH.sub.3 CH.sub.3 H L-1iN N N O CH.sub.3 CH.sub.3 H L-1jN N N O CH.sub.3 CH.sub.3 H L-1kN N N O CH.sub.3 CH.sub.3 H L-3aN N N O CH.sub.3 CH.sub.3 H L-3bN N N O CH.sub.3 CH.sub.3 H L-4aN N N O CH.sub.3 CH.sub.3 H L-7aN N N O CH.sub.3 CH.sub.3 H L-8aN N N O CH.sub.3 CH.sub.3 H L-8bN N N O CH.sub.3 CH.sub.3 H L-9aN N N O CH.sub.3 CH.sub.3 H L-12aN N N O CH.sub.3 CH.sub.3 H L-12bN N N O CH.sub.3 CH.sub.3 H L-14aN N N O CH.sub.3 CH.sub.3 H L-15aN N N O CH.sub.3 CH.sub.3 H L-16aN N N O CH.sub.3 CH.sub.3 H L-16bN N N O CH.sub.3 CH.sub.3 H L-18aN N N O CH.sub.3 CH.sub.3 H L-20aN N N O CH.sub.3 CH.sub.3 H L-22aN N N S CH.sub.3 CH.sub.3 H L-1aN N N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N N O OCH.sub.3 CH.sub.3 H L-1aN N N O OCH.sub.3 CH.sub.3 H L-1bN N N O OCH.sub.3 CH.sub.3 H L-1cN N N O OCH.sub.3 CH.sub.3 H L-1dN N N O OCH.sub.3 CH.sub.3 H L-1eN N N O OCH.sub.3 CH.sub.3 H L-1fN N N O OCH.sub.3 CH.sub.3 H L-1gN N N O OCH.sub.3 CH.sub.3 H L-1hN N N O OCH.sub.3 CH.sub.3 H L-1iN N N O OCH.sub.3 CH.sub.3 H L-1jN N N O OCH.sub.3 CH.sub.3 H L-1kN N N O OCH.sub.3 CH.sub.3 H L-3aN N N O OCH.sub.3 CH.sub.3 H L-3bN N N O OCH.sub.3 CH.sub.3 H L-4aN N N O OCH.sub.3 CH.sub.3 H L-7aN N N O OCH.sub.3 CH.sub.3 H L-8aN N N O OCH.sub.3 CH.sub.3 H L-8bN N N O OCH.sub.3 CH.sub.3 H L-9aN N N O OCH.sub.3 CH.sub.3 H L-12aN N N O OCH.sub.3 CH.sub.3 H L-12bN N N O OCH.sub.3 CH.sub.3 H L-14aN N N O OCH.sub.3 CH.sub.3 H L-15aN N N O OCH.sub.3 CH.sub.3 H L-16aN N N O OCH.sub.3 CH.sub.3 H L-16bN N N O OCH.sub.3 CH.sub.3 H L-18aN N N O OCH.sub.3 CH.sub.3 H L-20aN N N O OCH.sub.3 CH.sub.3 H L-22aN N N S OCH.sub.3 CH.sub.3 H L-1aN N N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N N O CH.sub.3 OCH.sub.3 H L-1aN N N O CH.sub.3 OCH.sub.3 H L-1bN N N O CH.sub.3 OCH.sub.3 H L-1cN N N O CH.sub.3 OCH.sub.3 H L-1dN N N O CH.sub.3 OCH.sub.3 H L-1eN N N O CH.sub.3 OCH.sub.3 H L-1fN N N O CH.sub.3 OCH.sub.3 H L-1gN N N O CH.sub.3 OCH.sub.3 H L-1hN N N O CH.sub.3 OCH.sub.3 H L-1iN N N O CH.sub.3 OCH.sub.3 H L-1jN N N O CH.sub.3 OCH.sub.3 H L-1kN N N O CH.sub.3 OCH.sub.3 H L-3aN N N O CH.sub.3 OCH.sub.3 H L-3bN N N O CH.sub.3 OCH.sub.3 H L-4aN N N O CH.sub.3 OCH.sub.3 H L-7aN N N O CH.sub.3 OCH.sub.3 H L-8aN N N O CH.sub.3 OCH.sub.3 H L-8bN N N O CH.sub.3 OCH.sub.3 H L-9aN N N O CH.sub.3 OCH.sub.3 H L-12aN N N O CH.sub.3 OCH.sub.3 H L-12bN N N O CH.sub.3 OCH.sub.3 H L-14aN N N O CH.sub.3 OCH.sub.3 H L-15aN N N O CH.sub.3 OCH.sub.3 H L-16aN N N O CH.sub.3 OCH.sub.3 H L-16bN N N O CH.sub.3 OCH.sub.3 H L-18aN N N O CH.sub.3 OCH.sub.3 H L-20aN N N O CH.sub.3 OCH.sub.3 H L-22aN N N S CH.sub.3 OCH.sub.3 H L-1aN N N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N N O OCH.sub.3 OCH.sub.3 H L-1aN N N O OCH.sub.3 OCH.sub.3 H L-1bN N N O OCH.sub.3 OCH.sub.3 H L-1cN N N O OCH.sub.3 OCH.sub.3 H L-1dN N N O OCH.sub.3 OCH.sub.3 H L-1eN N N O OCH.sub.3 OCH.sub.3 H L-1fN N N O OCH.sub.3 OCH.sub.3 H L-1gN N N O OCH.sub.3 OCH.sub.3 H L-1hN N N O OCH.sub.3 OCH.sub.3 H L-1iN N N O OCH.sub.3 OCH.sub.3 H L-1jN N N O OCH.sub.3 OCH.sub.3 H L-1kN N N O OCH.sub.3 OCH.sub.3 H L-3aN N N O OCH.sub.3 OCH.sub.3 H L-3bN N N O OCH.sub.3 OCH.sub.3 H L-4aN N N O OCH.sub.3 OCH.sub.3 H L-7aN N N O OCH.sub.3 OCH.sub.3 H L-8aN N N O OCH.sub.3 OCH.sub.3 H L-8bN N N O OCH.sub.3 OCH.sub.3 H L-9aN N N O OCH.sub.3 OCH.sub.3 H L-12aN N N O OCH.sub.3 OCH.sub.3 H L-12bN N N O OCH.sub.3 OCH.sub.3 H L-14aN N N O OCH.sub.3 OCH.sub.3 H L-15aN N N O OCH.sub.3 OCH.sub.3 H l-16aN N N O CH.sub.3 OCH.sub.3 H l-16bN N N O OCH.sub.3 OCH.sub.3 H L-18aN N N O OCH.sub.3 OCH.sub.3 H L-20aN N N O OCH.sub.3 OCH.sub.3 H L-22aN N N S OCH.sub.3 OCH.sub.3 H L-1aN N N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N O CH.sub.3 CH.sub.3 H L-1aN CH N O CH.sub.3 CH.sub.3 H L-1bN CH N O CH.sub.3 CH.sub.3 H L-1cN CH N O CH.sub.3 CH.sub.3 H L-1dN CH N O CH.sub.3 CH.sub.3 H L-1eN CH N O CH.sub.3 CH.sub.3 H L-1fN CH N O CH.sub.3 CH.sub.3 H L-1gN CH N O CH.sub.3 CH.sub.3 H L-1hN CH N O CH.sub.3 CH.sub.3 H L-1iN CH N O CH.sub.3 CH.sub.3 H L-1jN CH N O CH.sub.3 CH.sub.3 H L-1kN CH N O CH.sub.3 CH.sub.3 H L-3aN CH N O CH.sub.3 CH.sub.3 H L-3bN CH N O CH.sub.3 CH.sub.3 H L-4aN CH N O CH.sub.3 CH.sub.3 H L-7aN CH N O CH.sub.3 CH.sub.3 H L-8aN CH N O CH.sub.3 CH.sub.3 H L-8bN CH N O CH.sub.3 CH.sub.3 H L-9aN CH N O CH.sub.3 CH.sub.3 H L-12aN CH N O CH.sub.3 CH.sub.3 H L-12bN CH N O CH.sub.3 CH.sub.3 H L-14aN CH N O CH.sub.3 CH.sub.3 H L-15aN CH N O CH.sub.3 CH.sub.3 H L-16aN CH N O CH.sub.3 CH.sub.3 H L-16bN CH N O CH.sub.3 CH.sub.3 H L-18aN CH N O CH.sub.3 CH.sub.3 H L-20aN CH N O CH.sub.3 CH.sub.3 H L-22aN CH N S CH.sub.3 CH.sub.3 H L-1aN CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N O OCH.sub.3 CH.sub.3 H L-1aN CH N O OCH.sub.3 CH.sub.3 H L-1bN CH N O OCH.sub.3 CH.sub.3 H L-1cN CH N O OCH.sub.3 CH.sub.3 H L-1dN CH N O OCH.sub.3 CH.sub.3 H L-1eN CH N O OCH.sub.3 CH.sub.3 H L-1fN CH N O OCH.sub.3 CH.sub.3 H L-1gN CH N O OCH.sub.3 CH.sub.3 H L-1hN CH N O OCH.sub.3 CH.sub.3 H L-1iN CH N O OCH.sub.3 CH.sub.3 H L-1jN CH N O OCH.sub.3 CH.sub.3 H L-1kN CH N O OCH.sub.3 CH.sub.3 H L-3aN CH N O OCH.sub.3 CH.sub.3 H L-3bN CH N O OCH.sub.3 CH.sub.3 H L-4aN CH N O OCH.sub.3 CH.sub.3 H L-7aN CH N O OCH.sub.3 CH.sub.3 H L-8aN CH N O OCH.sub.3 CH.sub.3 H L-8bN CH N O OCH.sub.3 CH.sub.3 H L-9aN CH N O OCH.sub.3 CH.sub.3 H L-12aN CH N O OCH.sub.3 CH.sub.3 H L-12bN CH N O OCH.sub.3 CH.sub.3 H L-14aN CH N O OCH.sub.3 CH.sub.3 H L-15aN CH N O OCH.sub.3 CH.sub.3 H L-16aN CH N O OCH.sub.3 CH.sub.3 H L-16bN CH N O OCH.sub.3 CH.sub.3 H L-18aN CH N O OCH.sub.3 CH.sub.3 H L-20aN CH N O OCH.sub.3 CH.sub.3 H L-22aN CH N S OCH.sub.3 CH.sub.3 H L-1aN CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N O CH.sub.3 OCH.sub.3 H L-1aN CH N O CH.sub.3 OCH.sub.3 H L-1bN CH N O CH.sub.3 OCH.sub.3 H L-1cN CH N O CH.sub.3 OCH.sub.3 H L-1dN CH N O CH.sub.3 OCH.sub.3 H L-1eN CH N O CH.sub.3 OCH.sub.3 H L-1fN CH N O CH.sub.3 OCH.sub.3 H L-1gN CH N O CH.sub.3 OCH.sub.3 H L-1hN CH N O CH.sub.3 OCH.sub.3 H L-1iN CH N O CH.sub.3 OCH.sub.3 H L-1jN CH N O CH.sub.3 OCH.sub.3 H L-1kN CH N O CH.sub.3 OCH.sub.3 H L-3aN CH N O CH.sub.3 OCH.sub.3 H L-3bN CH N O CH.sub.3 OCH.sub.3 H L-4aN CH N O CH.sub.3 OCH.sub. 3 H L-7aN CH N O CH.sub.3 OCH.sub.3 H L-8aN CH N O CH.sub.3 OCH.sub.3 H L-8bN CH N O CH.sub.3 OCH.sub.3 H L-9aN CH N O CH.sub.3 OCH.sub.3 H L-12aN CH N O CH.sub.3 OCH.sub.3 H L-12bN CH N O CH.sub.3 OCH.sub.3 H L-14aN CH N O CH.sub.3 OCH.sub.3 H L-15aN CH N O CH.sub.3 OCH.sub.3 H L-16aN CH N O CH.sub.3 OCH.sub.3 H L-16bN CH N O CH.sub.3 OCH.sub.3 H L-18aN CH N O CH.sub.3 OCH.sub.3 H L-20aN CH N O CH.sub.3 OCH.sub.3 H L-22aN CH N S CH.sub.3 OCH.sub.3 H L-1aN CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N O OCH.sub.3 OCH.sub.3 H L-1aN CH N O OCH.sub.3 OCH.sub.3 H L-1bN CH N O OCH.sub.3 OCH.sub.3 H L-1cN CH N O OCH.sub.3 OCH.sub.3 H L-1dN CH N O OCH.sub.3 OCH.sub.3 H L-1eN CH N O OCH.sub.3 OCH.sub.3 H L-1fN CH N O OCH.sub.3 OCH.sub.3 H L-1gN CH N O OCH.sub.3 OCH.sub.3 H L-1hN CH N O OCH.sub.3 OCH.sub.3 H L-1iN CH N O OCH.sub.3 OCH.sub.3 H L-1jN CH N O OCH.sub.3 OCH.sub.3 H L-1kN CH N O OCH.sub.3 OCH.sub.3 H L-3aN CH N O OCH.sub.3 OCH.sub.3 H L-3bN CH N O OCH.sub.3 OCH.sub.3 H L-4aN CH N O OCH.sub.3 OCH.sub.3 H L-7aN CH N O OCH.sub.3 OCH.sub.3 H L-8aN CH N O OCH.sub.3 OCH.sub.3 H L-8bN CH N O OCH.sub.3 OCH.sub.3 H L-9aN CH N O OCH.sub.3 OCH.sub.3 H L-12aN CH N O OCH.sub.3 OCH.sub.3 H L-12bN CH N O OCH.sub.3 OCH.sub.3 H L-14aN CH N O OCH.sub.3 OCH.sub.3 H L-15aN CH N O OCH.sub.3 OCH.sub.3 H L-16aN CH N O OCH.sub.3 OCH.sub.3 H L-16bN CH N O OCH.sub.3 OCH.sub.3 H L-18aN CH N O OCH.sub.3 OCH.sub.3 H L-20aN CH N O OCH.sub.3 OCH.sub.3 H L-22aN CH N S OCH.sub.3 OCH.sub.3 H L-1aN CH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH O CH.sub.3 CH.sub.3 H L-1aN CH CH O CH.sub.3 CH.sub.3 H L-1bN CH CH O CH.sub.3 CH.sub.3 H L-1cN CH CH O CH.sub.3 CH.sub.3 H L-1dN CH CH O CH.sub.3 CH.sub.3 H L-1eN CH CH O CH.sub.3 CH.sub.3 H L-1fN CH CH O CH.sub.3 CH.sub.3 H L-1gN CH CH O CH.sub.3 CH.sub.3 H L-1hN CH CH O CH.sub.3 CH.sub.3 H L-1iN CH CH O CH.sub.3 CH.sub.3 H L-1jN CH CH O CH.sub.3 CH.sub.3 H L-1kN CH CH O CH.sub.3 CH.sub.3 H L-3aN CH CH O CH.sub.3 CH.sub.3 H L-3bN CH CH O CH.sub.3 CH.sub.3 H L-4aN CH CH O CH.sub.3 CH.sub.3 H L-7aN CH CH O CH.sub.3 CH.sub.3 H L-8aN CH CH O CH.sub. 3 CH.sub.3 H L-8bN CH CH O CH.sub.3 CH.sub.3 H L-9aN CH CH O CH.sub.3 CH.sub.3 H L-12aN CH CH O CH.sub.3 CH.sub.3 H L-12bN CH CH O CH.sub.3 CH.sub.3 H L-14aN CH CH O CH.sub.3 CH.sub.3 H L-15aN CH CH O CH.sub.3 CH.sub.3 H L-16aN CH CH O CH.sub.3 CH.sub.3 H L-16bN CH CH O CH.sub.3 CH.sub.3 H L-18aN CH CH O CH.sub.3 CH.sub.3 H L-20aN CH CH O CH.sub.3 CH.sub.3 H L-22aN CH CH S CH.sub.3 CH.sub.3 H L-1aN CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH O OCH.sub.3 CH.sub.3 H L-1aN CH CH O OCH.sub.3 CH.sub.3 H L-1bN CH CH O OCH.sub.3 CH.sub.3 H L-1cN CH CH O OCH.sub.3 CH.sub.3 H L-1dN CH CH O OCH.sub.3 CH.sub.3 H L-1eN CH CH O OCH.sub.3 CH.sub.3 H L-1fN CH CH O OCH.sub.3 CH.sub.3 H L-1gN CH CH O OCH.sub.3 CH.sub.3 H L-1hN CH CH O OCH.sub.3 CH.sub.3 H L-1iN CH CH O OCH.sub.3 CH.sub.3 H L-1jN CH CH O OCH.sub.3 CH.sub.3 H L-1kN CH CH O OCH.sub.3 CH.sub.3 H L-3aN CH CH O OCH.sub.3 CH.sub.3 H L-3bN CH CH O OCH.sub.3 CH.sub.3 H L-4aN CH CH O OCH.sub.3 CH.sub.3 H L-7aN CH CH O OCH.sub.3 CH.sub.3 H L-8aN CH CH O OCH.sub.3 CH.sub.3 H L-8bN CH CH O OCH.sub.3 CH.sub.3 H L-9aN CH CH O OCH.sub.3 CH.sub.3 H L-12aN CH CH O OCH.sub.3 CH.sub.3 H L-12bN CH CH O OCH.sub.3 CH.sub.3 H L-14aN CH CH O OCH.sub.3 CH.sub.3 H L-15aN CH CH O OCH.sub.3 CH.sub.3 H L-16aN CH CH O OCH.sub.3 CH.sub.3 H L-16bN CH CH O OCH.sub.3 CH.sub.3 H L-18aN CH CH O OCH.sub.3 CH.sub.3 H L-20aN CH CH O OCH.sub.3 CH.sub.3 H L-22aN CH CH S OCH.sub.3 CH.sub.3 H L-1aN CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH O CH.sub.3 OCH.sub.3 H L-1aN CH CH O CH.sub.3 OCH.sub.3 H L-1bN CH CH O CH.sub.3 OCH.sub.3 H L-1cN CH CH O CH.sub.3 OCH.sub.3 H L-1dN CH CH O CH.sub.3 OCH.sub.3 H L-1eN CH CH O CH.sub.3 OCH.sub.3 H L-1fN CH CH O CH.sub.3 OCH.sub.3 H L-1gN CH CH O CH.sub.3 OCH.sub.3 H L-1hN CH CH O CH.sub.3 OCH.sub.3 H L-1iN CH CH O CH.sub.3 OCH.sub.3 H L-1jN CH CH O CH.sub.3 OCH.sub.3 H L-1kN CH CH O CH.sub.3 OCH.sub.3 H L-3aN CH CH O CH.sub.3 OCH.sub.3 H L-3bN CH CH O CH.sub.3 OCH.sub.3 H L-4aN CH CH O CH.sub.3 OCH.sub.3 H L-7aN CH CH O CH.sub.3 OCH.sub.3 H L-8aN CH CH O CH.sub.3 OCH.sub.3 H L-8bN CH CH O CH.sub.3 OCH.sub.3 H L-9aN CH CH O CH.sub.3 OCH.sub.3 H L-12aN CH CH O CH.sub.3 OCH.sub.3 H L-12bN CH CH O CH.sub.3 OCH.sub.3 H L-14aN CH CH O CH.sub.3 OCH.sub.3 H L-15aN CH CH O CH.sub.3 OCH.sub.3 H L-16aN CH CH O CH.sub.3 OCH.sub.3 H L-16bN CH CH O CH.sub.3 OCH.sub.3 H L-18aN CH CH O CH.sub.3 OCH.sub.3 H L-20aN CH CH O CH.sub.3 OCH.sub.3 H L-22aN CH CH S CH.sub.3 OCH.sub.3 H L-1aN CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH O OCH.sub.3 OCH.sub.3 H L-1aN CH CH O OCH.sub.3 OCH.sub.3 H L-1bN CH CH O OCH.sub.3 OCH.sub.3 H L-1cN CH CH O OCH.sub.3 OCH.sub.3 H L-1dN CH CH O OCH.sub.3 OCH.sub.3 H L-1eN CH CH O OCH.sub.3 OCH.sub.3 H L-1fN CH CH O OCH.sub.3 OCH.sub.3 H L-1gN CH CH O OCH.sub.3 OCH.sub.3 H L-1hN CH CH O OCH.sub.3 OCH.sub.3 H L-1iN CH CH O OCH.sub.3 OCH.sub.3 H L-1jN CH CH O OCH.sub.3 OCH.sub.3 H L-1kN CH CH O OCH.sub.3 OCH.sub.3 H L-3aN CH CH O OCH.sub.3 OCH.sub.3 H L-3bN CH CH O OCH.sub.3 OCH.sub.3 H L-4aN CH CH O OCH.sub.3 OCH.sub.3 H L-7aN CH CH O OCH.sub.3 OCH.sub.3 H L-8aN CH CH O OCH.sub.3 OCH.sub.3 H L-8bN CH CH O OCH.sub.3 OCH.sub.3 H L-9aN CH CH O OCH.sub.3 OCH.sub.3 H L-12aN CH CH O OCH.sub.3 OCH.sub.3 H L-12bN CH CH O OCH.sub.3 OCH.sub.3 H L-14aN CH CH O OCH.sub.3 OCH.sub.3 H L-15aN CH CH O OCH.sub.3 OCH.sub.3 H L-16aN CH CH O OCH.sub.3 OCH.sub.3 H L-16bN CH CH O OCH.sub.3 OCH.sub.3 H L-18aN CH CH O OCH.sub.3 OCH.sub.3 H L-20aN CH CH O OCH.sub.3 OCH.sub.3 H L-22aN CH CH S OCH.sub.3 OCH.sub.3 H L-1aN CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1a__________________________________________________________________________ *N,N--diethylanilinium salt
TABLE 2______________________________________General Formula 2Z Z.sub.1 Z.sub.2 W X Y R L m.p.(.degree.C.)______________________________________CH N CH O CH.sub.3 CH.sub.3 H L-1a 210-212CH N CH O CH.sub.3 CH.sub.3 H L-1bCH N CH O CH.sub.3 CH.sub.3 H L-1cCH N CH O CH.sub.3 CH.sub.3 H L-1dCH N CH O CH.sub.3 CH.sub.3 H L-1eCH N CH O CH.sub.3 CH.sub.3 H L-1fCH N CH O CH.sub.3 CH.sub.3 H L-1gCH N CH O CH.sub.3 CH.sub.3 H L-1hCH N CH O CH.sub.3 CH.sub.3 H L-1iCH N CH O CH.sub.3 CH.sub.3 H L-1jCH N CH O CH.sub.3 CH.sub.3 H L-1kCH N CH O CH.sub.3 CH.sub.3 H L-1l 268-272CH N CH O CH.sub.3 CH.sub.3 H L-3aCH N CH O CH.sub.3 CH.sub.3 H L-3bCH N CH O CH.sub.3 CH.sub.3 H L-4aCH N CH O CH.sub. 3 CH.sub.3 H L-7aCH N CH O CH.sub.3 CH.sub.3 H L-8aCH N CH O CH.sub.3 CH.sub.3 H L-8bCH N CH O CH.sub.3 CH.sub.3 H L-9aCH N CH O CH.sub.3 CH.sub.3 H L-12aCH N CH O CH.sub.3 CH.sub.3 H L-12bCH N CH O CH.sub.3 CH.sub.3 H L-14aCH N CH O CH.sub.3 CH.sub.3 H L-15aCH N CH O CH.sub.3 CH.sub.3 H L-16aCH N CH O CH.sub.3 CH.sub.3 H L-16bCH N CH O CH.sub.3 CH.sub.3 H L-18aCH N CH O CH.sub.3 CH.sub.3 H L-20aCH N CH O CH.sub.3 CH.sub.3 H L-22aCH N CH S CH.sub.3 CH.sub.3 H L-1aCH N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH O OCH.sub.3 CH.sub.3 H L-1aCH N CH O OCH.sub.3 CH.sub.3 H L-1bCH N CH O OCH.sub.3 CH.sub.3 H L-1cCH N CH O OCH.sub.3 CH.sub.3 H L-1dCH N CH O OCH.sub.3 CH.sub.3 H L-1eCH N CH O OCH.sub.3 CH.sub.3 H L-1fCH N CH O OCH.sub.3 CH.sub.3 H L-1gCH N CH O OCH.sub.3 CH.sub.3 H L-1hCH N CH O OCH.sub.3 CH.sub.3 H L-1iCH N CH O OCH.sub.3 CH.sub.3 H L-1jCH N CH O OCH.sub.3 CH.sub.3 H L-1kCH N CH O OCH.sub.3 CH.sub.3 H L-3aCH N CH O OCH.sub.3 CH.sub.3 H L-3bCH N CH O OCH.sub.3 CH.sub.3 H L-4aCH N CH O OCH.sub.3 CH.sub.3 H L-7aCH N CH O OCH.sub.3 CH.sub.3 H L-8aCH N CH O OCH.sub.3 CH.sub.3 H L-8bCH N CH O OCH.sub.3 CH.sub.3 H L-9aCH N CH O OCH.sub.3 CH.sub.3 H L-12aCH N CH O OCH.sub.3 CH.sub.3 H L-12bCH N CH O OCH.sub.3 CH.sub.3 H L-14aCH N CH O OCH.sub.3 CH.sub.3 H L-15aCH N CH O OCH.sub.3 CH.sub.3 H L-16aCH N CH O OCH.sub.3 CH.sub.3 H L-16bCH N CH O OCH.sub.3 CH.sub.3 H L-18aCH N CH O OCH.sub.3 CH.sub.3 H L-20aCH N CH O OCH.sub.3 CH.sub.3 H L-22aCH N CH S OCH.sub.3 CH.sub.3 H L-1aCH N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH O CH.sub.3 OCH.sub.3 H L-1aCH N CH O CH.sub.3 OCH.sub.3 H L-1bCH N CH O CH.sub.3 OCH.sub.3 H L-1cCH N CH O CH.sub.3 OCH.sub.3 H L-1d 262-266CH N CH O CH.sub.3 OCH.sub.3 H L-1eCH N CH O CH.sub.3 OCH.sub.3 H L-1fCH N CH O CH.sub.3 OCH.sub.3 H L-1gCH N CH O CH.sub.3 OCH.sub.3 H L-1hCH N CH O CH.sub.3 OCH.sub.3 H L-1iCH N CH O CH.sub.3 OCH.sub.3 H L-1jCH N CH O CH.sub.3 OCH.sub.3 H L-1kCH N CH O CH.sub.3 OCH.sub.3 H L-1l 287-292CH N CH O CH.sub.3 OCH.sub.3 H L-3aCH N CH O CH.sub.3 OCH.sub.3 H L-3bCH N CH O CH.sub.3 OCH.sub.3 H L-4aCH N CH O CH.sub.3 OCH.sub.3 H L-7aCH N CH O CH.sub.3 OCH.sub.3 H L-8aCH N CH O CH.sub.3 OCH.sub.3 H L-8bCH N CH O CH.sub.3 OCH.sub.3 H L-9aCH N CH O CH.sub.3 OCH.sub.3 H L-12aCH N CH O CH.sub.3 OCH.sub.3 H L-12bCH N CH O CH.sub.3 OCH.sub.3 H L-14aCH N CH O CH.sub.3 OCH.sub.3 H L-15aCH N CH O CH.sub.3 OCH.sub.3 H L-16aCH N CH O CH.sub.3 OCH.sub.3 H L-16bCH N CH O CH.sub.3 OCH.sub.3 H L-18aCH N CH O CH.sub.3 OCH.sub.3 H L-20aCH N CH O CH.sub.3 OCH.sub.3 H L-22aCH N CH S CH.sub.3 OCH.sub.3 H L-1aCH N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N CH O OCH.sub.3 OCH.sub.3 H L-1aCH N CH O OCH.sub.3 OCH.sub.3 H L-1bCH N CH O OCH.sub.3 OCH.sub.3 H L-1cCH N CH O OCH.sub.3 OCH.sub.3 H L-1dCH N CH O OCH.sub.3 OCH.sub.3 H L-1eCH N CH O OCH.sub.3 OCH.sub.3 H L-1fCH N CH O OCH.sub.3 OCH.sub.3 H L-1gCH N CH O OCH.sub.3 OCH.sub.3 H L-1hCH N CH O OCH.sub.3 OCH.sub.3 H L-1iCH N CH O OCH.sub.3 OCH.sub.3 H L-1jCH N CH O OCH.sub.3 OCH.sub.3 H L-1kCH N CH O OCH.sub.3 OCH.sub.3 H L-3aCH N CH O OCH.sub.3 OCH.sub.3 H L-3bCH N CH O OCH.sub.3 OCH.sub.3 H L-4aCH N CH O OCH.sub.3 OCH.sub.3 H L-7aCH N CH O OCH.sub.3 OCH.sub.3 H L-8aCH N CH O OCH.sub.3 OCH.sub.3 H L-8bCH N CH O OCH.sub.3 OCH.sub.3 H L-9aCH N CH O OCH.sub.3 OCH.sub.3 H L-12aCH N CH O OCH.sub.3 OCH.sub.3 H L-12bCH N CH O OCH.sub.3 OCH.sub.3 H L-14aCH N CH O OCH.sub.3 OCH.sub.3 H L-15aCH N CH O OCH.sub.3 OCH.sub.3 H L-16aCH N CH O OCH.sub.3 OCH.sub.3 H L-16bCH N CH O OCH.sub.3 OCH.sub.3 H L-18aCH N CH O OCH.sub.3 OCH.sub.3 H L-20aCH N CH O OCH.sub.3 OCH.sub.3 H L-22aCH N CH S OCH.sub.3 OCH.sub.3 H L-1aCH N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N N O CH.sub.3 CH.sub.3 H L-1aCH N N O CH.sub.3 CH.sub.3 H L-1bCH N N O CH.sub.3 CH.sub.3 H L-1cCH N N O CH.sub.3 CH.sub.3 H L-1d 242-247CH N N O CH.sub.3 CH.sub.3 H L-1eCH N N O CH.sub.3 CH.sub.3 H L-1fCH N N O CH.sub.3 CH.sub.3 H L-1gCH N N O CH.sub.3 CH.sub.3 H L-1hCH N N O CH.sub.3 CH.sub.3 H L-1iCH N N O CH.sub.3 CH.sub.3 H L-1jCH N N O CH.sub.3 CH.sub.3 H L-1kCH N N O CH.sub.3 CH.sub.3 H L-3aCH N N O CH.sub.3 CH.sub.3 H L-3bCH N N O CH.sub.3 CH.sub.3 H L-4aCH N N O CH.sub.3 CH.sub.3 H L-7aCH N N O CH.sub.3 CH.sub.3 H L-8aCH N N O CH.sub. 3 CH.sub.3 H L-8bCH N N O CH.sub.3 CH.sub.3 H L-9aCH N N O CH.sub.3 CH.sub.3 H L-12aCH N N O CH.sub.3 CH.sub.3 H L-12bCH N N O CH.sub.3 CH.sub.3 H L-14aCH N N O CH.sub.3 CH.sub.3 H L-15aCH N N O CH.sub.3 CH.sub.3 H L-16aCH N N O CH.sub.3 CH.sub.3 H L-16bCH N N O CH.sub.3 CH.sub.3 H L-18aCH N N O CH.sub.3 CH.sub.3 H L-20aCH N N O CH.sub.3 CH.sub.3 H L-22aCH N N S CH.sub.3 CH.sub.3 H L-1aCH N N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N N O OCH.sub.3 CH.sub.3 H L-1aCH N N O OCH.sub.3 CH.sub.3 H L-1bCH N N O OCH.sub.3 CH.sub.3 H L-1cCH N N O OCH.sub.3 CH.sub.3 H L-1dCH N N O OCH.sub.3 CH.sub.3 H L-1eCH N N O OCH.sub.3 CH.sub.3 H L-1fCH N N O OCH.sub.3 CH.sub.3 H L-1gCH N N O OCH.sub.3 CH.sub.3 H L-1hCH N N O OCH.sub.3 CH.sub.3 H L-1iCH N N O OCH.sub.3 CH.sub.3 H L-1jCH N N O OCH.sub.3 CH.sub.3 H L-1kCH N N O OCH.sub.3 CH.sub.3 H L-3aCH N N O OCH.sub.3 CH.sub.3 H L-3bCH N N O OCH.sub.3 CH.sub.3 H L-4aCH N N O OCH.sub.3 CH.sub.3 H L-7aCH N N O OCH.sub.3 CH.sub.3 H L-8aCH N N O OCH.sub.3 CH.sub.3 H L-8bCH N N O OCH.sub.3 CH.sub.3 H L-9aCH N N O OCH.sub.3 CH.sub.3 H L-12aCH N N O OCH.sub.3 CH.sub.3 H L-12bCH N N O OCH.sub.3 CH.sub.3 H L-14aCH N N O OCH.sub.3 CH.sub.3 H L-15aCH N N O OCH.sub.3 CH.sub.3 H L-16aCH N N O OCH.sub.3 CH.sub.3 H L-16bCH N N O OCH.sub.3 CH.sub.3 H L-18aCH N N O OCH.sub.3 CH.sub.3 H L-20aCH N N O OCH.sub.3 CH.sub.3 H L-22aCH N N S OCH.sub.3 CH.sub.3 H L-1aCH N N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N N O CH.sub.3 OCH.sub.3 H L-1aCH N N O CH.sub.3 OCH.sub.3 H L-1bCH N N O CH.sub.3 OCH.sub.3 H L-1cCH N N O CH.sub.3 OCH.sub.3 H L-1dCH N N O CH.sub.3 OCH.sub.3 H L-1eCH N N O CH.sub.3 OCH.sub.3 H L-1fCH N N O CH.sub.3 OCH.sub.3 H L-1gCH N N O CH.sub.3 OCH.sub.3 H L-1hCH N N O CH.sub.3 OCH.sub.3 H L-1iCH N N O CH.sub.3 OCH.sub.3 H L-1jCH N N O CH.sub.3 OCH.sub.3 H L-1kCH N N O CH.sub.3 OCH.sub.3 H L-3aCH N N O CH.sub.3 OCH.sub.3 H L-3bCH N N O CH.sub.3 OCH.sub.3 H L-4aCH N N O CH.sub.3 OCH.sub.3 H L-7aCH N N O CH.sub.3 OCH.sub.3 H L-8aCH N N O CH.sub.3 OCH.sub.3 H L-8bCH N N O CH.sub.3 OCH.sub.3 H L-9aCH N N O CH.sub.3 OCH.sub.3 H L-12aCH N N O CH.sub.3 OCH.sub.3 H L-12bCH N N O CH.sub.3 OCH.sub.3 H L-14aCH N N O CH.sub.3 OCH.sub.3 H L-15aCH N N O CH.sub.3 OCH.sub.3 H L-16aCH N N O CH.sub.3 OCH.sub.3 H L-16bCH N N O CH.sub.3 OCH.sub.3 H L-18aCH N N O CH.sub.3 OCH.sub.3 H L-20aCH N N O CH.sub.3 OCH.sub.3 H L-22aCH N N S CH.sub.3 OCH.sub.3 H L-1aCH N N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N N O OCH.sub.3 OCH.sub.3 H L-1aCH N N O OCH.sub.3 OCH.sub.3 H L-1bCH N N O OCH.sub.3 OCH.sub.3 H L-1cCH N N O OCH.sub.3 OCH.sub.3 H L-1dCH N N O OCH.sub.3 OCH.sub.3 H L-1eCH N N O OCH.sub.3 OCH.sub.3 H L-1fCH N N O OCH.sub.3 OCH.sub.3 H L-1gCH N N O OCH.sub.3 OCH.sub.3 H L-1hCH N N O OCH.sub.3 OCH.sub.3 H L-1iCH N N O OCH.sub.3 OCH.sub.3 H L-1jCH N N O OCH.sub.3 OCH.sub.3 H L-1kCH N N O OCH.sub.3 OCH.sub.3 H L-3aCH N N O OCH.sub.3 OCH.sub.3 H L-3bCH N N O OCH.sub.3 OCH.sub.3 H L-4aCH N N O OCH.sub.3 OCH.sub.3 H L-7aCH N N O OCH.sub.3 OCH.sub.3 H L-8aCH N N O OCH.sub.3 OCH.sub.3 H L-8bCH N N O OCH.sub.3 OCH.sub.3 H L-9aCH N N O OCH.sub.3 OCH.sub.3 H L-12aCH N N O OCH.sub.3 OCH.sub.3 H L-12bCH N N O OCH.sub.3 OCH.sub.3 H L-14aCH N N O OCH.sub.3 OCH.sub.3 H L-15aCH N N O OCH.sub.3 OCH.sub.3 H L-16aCH N N O OCH.sub.3 OCH.sub.3 H L-16bCH N N O OCH.sub.3 OCH.sub.3 H L-18aCH N N O OCH.sub.3 OCH.sub.3 H L-20aCH N N O OCH.sub.3 OCH.sub.3 H L-22aCH N N S OCH.sub.3 OCH.sub.3 H L-1aCH N N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N O CH.sub.3 CH.sub.3 H L-1aCH CH N O CH.sub.3 CH.sub.3 H L-1 225-228CH CH N O CH.sub.3 CH.sub.3 H L-1cCH CH N O CH.sub.3 CH.sub.3 H L-1d 292-297CH CH N O CH.sub.3 CH.sub.3 H L-1eCH CH N O CH.sub.3 CH.sub.3 H L-1fCH CH N O CH.sub.3 CH.sub.3 H L-1gCH CH N O CH.sub.3 CH.sub.3 H L-1hCH CH N O CH.sub.3 CH.sub.3 H L-1iCH CH N O CH.sub.3 CH.sub.3 H L-1jCH CH N O CH.sub.3 CH.sub.3 H L-1kCH CH N O CH.sub.3 CH.sub.3 H L-1l 308-311 (d)CH CH N O CH.sub.3 CH.sub.3 H L-3aCH CH N O CH.sub.3 CH.sub.3 H L-3bCH CH N O CH.sub.3 CH.sub.3 H L-4aCH CH N O CH.sub.3 CH.sub.3 H L-7aCH CH N O CH.sub.3 CH.sub.3 H L-8aCH CH N O CH.sub.3 CH.sub.3 H L-8bCH CH N O CH.sub.3 CH.sub.3 H L-9aCH CH N O CH.sub.3 CH.sub.3 H L-12aCH CH N O CH.sub.3 CH.sub.3 H L-12bCH CH N O CH.sub.3 CH.sub.3 H L-14aCH CH N O CH.sub.3 CH.sub.3 H L-15aCH CH N O CH.sub.3 CH.sub.3 H L-16aCH CH N O CH.sub.3 CH.sub.3 H L-16bCH CH N O CH.sub.3 CH.sub.3 H L-18aCH CH N O CH.sub.3 CH.sub.3 H L-20aCH CH N O CH.sub.3 CH.sub.3 H L-22aCH CH N S CH.sub.3 CH.sub.3 H L-1aCH CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N O H CH.sub.3 H L-1d 265-272CH CH N O H CH.sub.3 H L-1l 219-225CH CH N O OCH.sub.3 CH.sub.3 H L-1aCH CH N O OCH.sub.3 CH.sub.3 H L-1bCH CH N O OCH.sub.3 CH.sub.3 H L-1cCH CH N O OCH.sub.3 CH.sub.3 H L-1dCH CH N O OCH.sub.3 CH.sub.3 H L-1eCH CH N O OCH.sub.3 CH.sub.3 H L-1fCH CH N O OCH.sub.3 CH.sub.3 H L-1gCH CH N O OCH.sub.3 CH.sub.3 H L-1hCH CH N O OCH.sub.3 CH.sub.3 H L-1iCH CH N O OCH.sub.3 CH.sub.3 H L-1jCH CH N O OCH.sub.3 CH.sub.3 H L-1kCH CH N O OCH.sub.3 CH.sub.3 H L-3aCH CH N O OCH.sub.3 CH.sub.3 H L-3bCH CH N O OCH.sub.3 CH.sub.3 H L-4aCH CH N O OCH.sub.3 CH.sub.3 H L-7aCH CH N O OCH.sub.3 CH.sub.3 H L-8aCH CH N O OCH.sub.3 CH.sub.3 H L-8bCH CH N O OCH.sub.3 CH.sub.3 H L-9aCH CH N O OCH.sub.3 CH.sub.3 H L-12aCH CH N O OCH.sub.3 CH.sub.3 H L-12bCH CH N O OCH.sub.3 CH.sub.3 H L-14aCH CH N O OCH.sub.3 CH.sub.3 H L-15aCH CH N O OCH.sub.3 CH.sub.3 H L-16aCH CH N O OCH.sub.3 CH.sub.3 H L-16bCH CH N O OCH.sub.3 CH.sub.3 H L-18aCH CH N O OCH.sub.3 CH.sub.3 H L-20aCH CH N O OCH.sub.3 CH.sub.3 H L-22aCH CH N S OCH.sub.3 CH.sub.3 H L-1aCH CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N O CH.sub.3 OCH.sub.3 H L-1aCH CH N O CH.sub.3 OCH.sub.3 H L-1bCH CH N O CH.sub.3 OCH.sub.3 H L-1cCH CH N O CH.sub.3 OCH.sub.3 H L-1dCH CH N O CH.sub.3 OCH.sub.3 H L-1eCH CH N O CH.sub.3 OCH.sub.3 H L-1fCH CH N O CH.sub.3 OCH.sub.3 H L-1gCH CH N O CH.sub.3 OCH.sub.3 H L-1hCH CH N O CH.sub.3 OCH.sub.3 H L-1iCH CH N O CH.sub.3 OCH.sub.3 H L-1jCH CH N O CH.sub.3 OCH.sub.3 H L-1kCH CH N O CH.sub.3 OCH.sub.3 H L-3aCH CH N O CH.sub.3 OCH.sub.3 H L-3bCH CH N O CH.sub.3 OCH.sub.3 H L-4aCH CH N O CH.sub.3 OCH.sub.3 H L-7aCH CH N O CH.sub.3 OCH.sub.3 H L-8aCH CH N O CH.sub.3 OCH.sub.3 H L-8bCH CH N O CH.sub.3 OCH.sub.3 H L-9aCH CH N O CH.sub.3 OCH.sub.3 H L-12aCH CH N O CH.sub.3 OCH.sub.3 H L-12bCH CH N O CH.sub.3 OCH.sub.3 H L-14aCH CH N O CH.sub.3 OCH.sub.3 H L-15aCH CH N O CH.sub.3 OCH.sub.3 H L-16aCH CH N O CH.sub.3 OCH.sub.3 H L-16bCH CH N O CH.sub.3 OCH.sub.3 H L-18aCH CH N O CH.sub.3 OCH.sub.3 H L-20aCH CH N O CH.sub.3 OCH.sub.3 H L-22aCH CH N S CH.sub.3 OCH.sub.3 H L-1aCH CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N O OCH.sub.3 OCH.sub.3 H L-1aCH CH N O OCH.sub.3 OCH.sub.3 H L-1bCH CH N O OCH.sub.3 OCH.sub.3 H L-1cCH CH N O OCH.sub.3 OCH.sub.3 H L-1dCH CH N O OCH.sub.3 OCH.sub.3 H L-1eCH CH N O OCH.sub.3 OCH.sub.3 H L-1fCH CH N O OCH.sub.3 OCH.sub.3 H L-1gCH CH N O OCH.sub.3 OCH.sub.3 H L-1hCH CH N O OCH.sub.3 OCH.sub.3 H L-1iCH CH N O OCH.sub.3 OCH.sub.3 H L-1jCH CH N O OCH.sub.3 OCH.sub.3 H L-1kCH CH N O OCH.sub.3 OCH.sub.3 H L-3aCH CH N O OCH.sub.3 OCH.sub.3 H L-3bCH CH N O OCH.sub.3 OCH.sub.3 H L-4aCH CH N O OCH.sub.3 OCH.sub.3 H L-7aCH CH N O OCH.sub.3 OCH.sub.3 H L-8aCH CH N O OCH.sub.3 OCH.sub.3 H L-8bCH CH N O OCH.sub.3 OCH.sub.3 H L-9aCH CH N O OCH.sub.3 OCH.sub.3 H L-12aCH CH N O OCH.sub.3 OCH.sub.3 H L-12bCH CH N O OCH.sub.3 OCH.sub.3 H L-14aCH CH N O OCH.sub.3 OCH.sub.3 H L-15aCH CH N O OCH.sub.3 OCH.sub.3 H L-16aCH CH N O OCH.sub.3 OCH.sub.3 H L-16bCH CH N O OCH.sub.3 OCH.sub.3 H L-18aCH CH N O OCH.sub.3 OCH.sub.3 H L-20aCH CH N O OCH.sub.3 OCH.sub.3 H L-22aCH CH N S OCH.sub.3 OCH.sub.3 H L-1aCH CH N O OCH.sub.3 OCH.sub.3 CH.sub. 3 L-1aCH CH CH O CH.sub.3 CH.sub.3 H L-1a 200-202CH CH CH O CH.sub.3 CH.sub.3 H L-1b 199-202CH CH CH O CH.sub.3 CH.sub.3 H L-1cCH CH CH O CH.sub.3 CH.sub.3 H L-1dCH CH CH O CH.sub.3 CH.sub.3 H L-1eCH CH CH O CH.sub.3 CH.sub.3 H L-1fCH CH CH O CH.sub.3 CH.sub.3 H L-1gCH CH CH O CH.sub.3 CH.sub.3 H L-1hCH CH CH O CH.sub.3 CH.sub.3 H L-1iCH CH CH O CH.sub.3 CH.sub.3 H L-1jCH CH CH O CH.sub.3 CH.sub.3 H L-1kCH CH CH O CH.sub.3 CH.sub.3 H L-3aCH CH CH O CH.sub.3 CH.sub.3 H L-3bCH CH CH O CH.sub.3 CH.sub.3 H L-4aCH CH CH O CH.sub.3 CH.sub.3 H L-7aCH CH CH O CH.sub.3 CH.sub.3 H L-8aCH CH CH O CH.sub.3 CH.sub.3 H L-8bCH CH CH O CH.sub.3 CH.sub.3 H L-9aCH CH CH O CH.sub.3 CH.sub.3 H L-12aCH CH CH O CH.sub.3 CH.sub.3 H L-12bCH CH CH O CH.sub.3 CH.sub.3 H L-14aCH CH CH O CH.sub.3 CH.sub.3 H L-15aCH CH CH O CH.sub.3 CH.sub.3 H L-16aCH CH CH O CH.sub.3 CH.sub.3 H L-16bCH CH CH O CH.sub.3 CH.sub.3 H L-18aCH CH CH O CH.sub.3 CH.sub.3 H L-20aCH CH CH O CH.sub.3 CH.sub.3 H L-22aCH CH CH S CH.sub.3 CH.sub.3 H L-1aCH CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH O OCH.sub.3 CH.sub.3 H L-1aCH CH CH O OCH.sub.3 CH.sub.3 H L-1bCH CH CH O OCH.sub.3 CH.sub.3 H L-1cCH CH CH O OCH.sub.3 CH.sub.3 H L-1dCH CH CH O OCH.sub.3 CH.sub.3 H L-1eCH CH CH O OCH.sub.3 CH.sub.3 H L-1fCH CH CH O OCH.sub.3 CH.sub.3 H L-1gCH CH CH O OCH.sub.3 CH.sub.3 H L-1hCH CH CH O OCH.sub.3 CH.sub.3 H L-1iCH CH CH O OCH.sub.3 CH.sub.3 H L-1jCH CH CH O OCH.sub.3 CH.sub.3 H L-1kCH CH CH O OCH.sub.3 CH.sub.3 H L-3aCH CH CH O OCH.sub.3 CH.sub.3 H L-3bCH CH CH O OCH.sub.3 CH.sub.3 H L-4aCH CH CH O OCH.sub.3 CH.sub.3 H L-7aCH CH CH O OCH.sub.3 CH.sub.3 H L-8aCH CH CH O OCH.sub.3 CH.sub.3 H L-8bCH CH CH O OCH.sub.3 CH.sub.3 H L-9aCH CH CH O OCH.sub.3 CH.sub.3 H L-12aCH CH CH O OCH.sub.3 CH.sub.3 H L-12bCH CH CH O OCH.sub.3 CH.sub.3 H L-14aCH CH CH O OCH.sub.3 CH.sub.3 H L-15aCH CH CH O OCH.sub.3 CH.sub.3 H L-16aCH CH CH O OCH.sub.3 CH.sub.3 H L-16bCH CH CH O OCH.sub.3 CH.sub.3 H L-18aCH CH CH O OCH.sub.3 CH.sub.3 H L-20aCH CH CH O OCH.sub.3 CH.sub.3 H L-22aCH CH CH S OCH.sub.3 CH.sub.3 H L-1aCH CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH O CH.sub.3 OCH.sub.3 H L-1aCH CH CH O CH.sub.3 OCH.sub.3 H L-1bCH CH CH O CH.sub.3 OCH.sub.3 H L-1cCH CH CH O CH.sub.3 OCH.sub.3 H L-1dCH CH CH O CH.sub.3 OCH.sub.3 H L-1eCH CH CH O CH.sub.3 OCH.sub.3 H L-1fCH CH CH O CH.sub.3 OCH.sub.3 H L-1gCH CH CH O CH.sub.3 OCH.sub.3 H L-1hCH CH CH O CH.sub.3 OCH.sub.3 H L-1iCH CH CH O CH.sub.3 OCH.sub.3 H L-1jCH CH CH O CH.sub.3 OCH.sub.3 H L-1kCH CH CH O CH.sub.3 OCH.sub.3 H L-3aCH CH CH O CH.sub.3 OCH.sub.3 H L-3bCH CH CH O CH.sub.3 OCH.sub.3 H L-4aCH CH CH O CH.sub.3 OCH.sub.3 H L-7aCH CH CH O CH.sub.3 OCH.sub.3 H L-8aCH CH CH O CH.sub.3 OCH.sub.3 H L-8bCH CH CH O CH.sub.3 OCH.sub.3 H L-9aCH CH CH O CH.sub.3 OCH.sub.3 H L-12aCH CH CH O CH.sub.3 OCH.sub.3 H L-12bCH CH CH O CH.sub.3 OCH.sub.3 H L-14aCH CH CH O CH.sub.3 OCH.sub.3 H L-15aCH CH CH O CH.sub.3 OCH.sub.3 H L-16aCH CH CH O CH.sub.3 OCH.sub.3 H L-16bCH CH CH O CH.sub.3 OCH.sub.3 H L-18aCH CH CH O CH.sub.3 OCH.sub.3 H L-20aCH CH CH O CH.sub.3 OCH.sub.3 H L-22aCH CH CH S CH.sub.3 OCH.sub.3 H L-1aCH CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH O OCH.sub.3 OCH.sub.3 H L-1aCH CH CH O OCH.sub.3 OCH.sub.3 H L-1bCH CH CH O OCH.sub.3 OCH.sub.3 H L-1cCH CH CH O OCH.sub.3 OCH.sub.3 H L-1dCH CH CH O OCH.sub.3 OCH.sub.3 H L-1eCH CH CH O OCH.sub.3 OCH.sub.3 H L-1fCH CH CH O OCH.sub.3 OCH.sub.3 H L-1gCH CH CH O OCH.sub.3 OCH.sub.3 H L-1hCH CH CH O OCH.sub.3 OCH.sub.3 H L-1iCH CH CH O OCH.sub.3 OCH.sub.3 H L-1jCH CH CH O OCH.sub.3 OCH.sub.3 H L-1kCH CH CH O OCH.sub.3 OCH.sub.3 H L-3aCH CH CH O OCH.sub.3 OCH.sub.3 H L-3bCH CH CH O OCH.sub.3 OCH.sub.3 H L-4aCH CH CH O OCH.sub.3 OCH.sub.3 H L-7aCH CH CH O OCH.sub.3 OCH.sub.3 H L-8aCH CH CH O OCH.sub.3 OCH.sub.3 H L-8bCH CH CH O OCH.sub.3 OCH.sub.3 H L-9aCH CH CH O OCH.sub.3 OCH.sub.3 H L-12aCH CH CH O OCH.sub.3 OCH.sub.3 H L-12bCH CH CH O OCH.sub.3 OCH.sub.3 H L-14aCH CH CH O OCH.sub.3 OCH.sub.3 H L-15aCH CH CH O OCH.sub.3 OCH.sub.3 H L-16aCH CH CH O OCH.sub.3 OCH.sub.3 H L-16bCH CH CH O OCH.sub.3 OCH.sub.3 H L-18aCH CH CH O OCH.sub.3 OCH.sub.3 H L-20aCH CH CH O OCH.sub.3 OCH.sub.3 H L-22aCH CH CH S OCH.sub.3 OCH.sub.3 H L-1aCH CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH O CH.sub.3 CH.sub.3 H L-1aN N CH O CH.sub.3 CH.sub.3 H L-1bN N CH O CH.sub.3 CH.sub.3 H L-1cN N CH O CH.sub.3 CH.sub.3 H L-1dN N CH O CH.sub.3 CH.sub.3 H L-1eN N CH O CH.sub.3 CH.sub.3 H L-1fN N CH O CH.sub.3 CH.sub.3 H L-1gN N CH O CH.sub.3 CH.sub.3 H L-1hN N CH O CH.sub.3 CH.sub.3 H L-1iN N CH O CH.sub.3 CH.sub.3 H L-1jN N CH O CH.sub.3 CH.sub.3 H L-1kN N CH O CH.sub.3 CH.sub.3 H L-3aN N CH O CH.sub.3 CH.sub.3 H L-3bN N CH O CH.sub.3 CH.sub.3 H L-4aN N CH O CH.sub.3 CH.sub.3 H L-7aN N CH O CH.sub.3 CH.sub.3 H L-8aN N CH O CH.sub.3 CH.sub.3 H L-8bN N CH O CH.sub.3 CH.sub.3 H L-9aN N CH O CH.sub.3 CH.sub.3 H L-12aN N CH O CH.sub.3 CH.sub.3 H L-12bN N CH O CH.sub.3 CH.sub.3 H L-14aN N CH O CH.sub.3 CH.sub.3 H L-15aN N CH O CH.sub.3 CH.sub.3 H L-16aN N CH O CH.sub.3 CH.sub.3 H L-16bN N CH O CH.sub.3 CH.sub.3 H L-18aN N CH O CH.sub.3 CH.sub.3 H L-20aN N CH O CH.sub.3 CH.sub.3 H L-22aN N CH S CH.sub.3 CH.sub.3 H L-1aN N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH O OCH.sub.3 CH.sub.3 H L-1aN N CH O OCH.sub.3 CH.sub.3 H L-1bN N CH O OCH.sub.3 CH.sub.3 H L-1cN N CH O OCH.sub.3 CH.sub.3 H L-1dN N CH O OCH.sub.3 CH.sub.3 H L-1aN N CH O OCH.sub.3 CH.sub.3 H L-1fN N CH O OCH.sub.3 CH.sub.3 H L-1gN N CH O OCH.sub.3 CH.sub.3 H L-1hN N CH O OCH.sub.3 CH.sub.3 H L-1iN N CH O OCH.sub.3 CH.sub.3 H L-1jN N CH O OCH.sub.3 CH.sub.3 H L-1kN N CH O OCH.sub.3 CH.sub.3 H L-3aN N CH O OCH.sub.3 CH.sub.3 H L-3bN N CH O OCH.sub.3 CH.sub.3 H L-4aN N CH O OCH.sub.3 CH.sub.3 H L-7aN N CH O OCH.sub.3 CH.sub.3 H L-8aN N CH O OCH.sub.3 CH.sub.3 H L-8bN N CH O OCH.sub.3 CH.sub.3 H L-9aN N CH O OCH.sub.3 CH.sub.3 H L-12aN N CH O OCH.sub.3 CH.sub.3 H L-12bN N CH O OCH.sub.3 CH.sub.3 H L-14aN N CH O OCH.sub.3 CH.sub.3 H L-15aN N CH O OCH.sub.3 CH.sub.3 H L-16aN N CH O OCH.sub.3 CH.sub.3 H L-16bN N CH O OCH.sub.3 CH.sub.3 H L-18aN N CH O OCH.sub.3 CH.sub.3 H L-20aN N CH O OCH.sub.3 CH.sub.3 H L-22aN N CH S OCH.sub.3 CH.sub.3 H L-1aN N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH O CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 H L-1bN N CH O CH.sub.3 OCH.sub.3 H L-1cN N CH O CH.sub.3 OCH.sub.3 H L-1dN N CH O CH.sub.3 OCH.sub.3 H L-1eN N CH O CH.sub.3 OCH.sub.3 H L-1fN N CH O CH.sub.3 OCH.sub.3 H L-1gN N CH O CH.sub.3 OCH.sub.3 H L-1hN N CH O CH.sub.3 OCH.sub.3 H L-1iN N CH O CH.sub.3 OCH.sub.3 H L-1jN N CH O CH.sub.3 OCH.sub.3 H L-1kN N CH O CH.sub.3 OCH.sub.3 H L-3aN N CH O CH.sub.3 OCH.sub.3 H L-3bN N CH O CH.sub.3 OCH.sub.3 H L-4aN N CH O CH.sub.3 OCH.sub.3 H L-7aN N CH O CH.sub.3 OCH.sub.3 H L-8aN N CH O CH.sub.3 OCH.sub.3 H L-8bN N CH O CH.sub.3 OCH.sub.3 H L-9aN N CH O CH.sub.3 OCH.sub.3 H L-12aN N CH O CH.sub.3 OCH.sub.3 H L-12bN N CH O CH.sub.3 OCH.sub.3 H L-14aN N CH O CH.sub.3 OCH.sub.3 H L-15aN N CH O CH.sub.3 OCH.sub.3 H L-16aN N CH O CH.sub.3 OCH.sub.3 H L-16bN N CH O CH.sub.3 OCH.sub.3 H L-18aN N CH O CH.sub.3 OCH.sub.3 H L-20aN N CH O CH.sub.3 OCH.sub.3 H L-22aN N CH S CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH O OCH.sub.3 OCH.sub.3 H L-1aN N CH O OCH.sub.3 OCH.sub.3 H L-1bN N CH O OCH.sub.3 OCH.sub.3 H L-1cN N CH O OCH.sub.3 OCH.sub.3 H L-1dN N CH O OCH.sub.3 OCH.sub.3 H L-1eN N CH O OCH.sub.3 OCH.sub.3 H L-1fN N CH O OCH.sub.3 OCH.sub.3 H L-1gN N CH O OCH.sub.3 OCH.sub.3 H L-1hN N CH O OCH.sub.3 OCH.sub.3 H L-1iN N CH O OCH.sub.3 OCH.sub.3 H L-1jN N CH O OCH.sub.3 OCH.sub.3 H L-1kN N CH O OCH.sub.3 OCH.sub.3 H L-3aN N CH O OCH.sub.3 OCH.sub.3 H L-3bN N CH O OCH.sub.3 OCH.sub.3 H L-4aN N CH O OCH.sub.3 OCH.sub.3 H L-7aN N CH O OCH.sub.3 OCH.sub. 3 H L-8aN N CH O OCH.sub.3 OCH.sub.3 H L-8bN N CH O OCH.sub.3 OCH.sub.3 H L-9aN N CH O OCH.sub.3 OCH.sub.3 H L-12aN N CH O OCH.sub.3 OCH.sub.3 H L-12bN N CH O OCH.sub.3 OCH.sub.3 H L-14aN N CH O OCH.sub.3 OCH.sub.3 H L-15aN N CH O OCH.sub.3 OCH.sub.3 H L-16aN N CH O OCH.sub.3 OCH.sub.3 H L-16bN N CH O OCH.sub.3 OCH.sub.3 H L-18aN N CH O OCH.sub.3 OCH.sub.3 H L-20aN N CH O OCH.sub.3 OCH.sub.3 H L-22aN N CH S OCH.sub.3 OCH.sub.3 H L-1aN N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N N O CH.sub.3 CH.sub.3 H L-1aN N N O CH.sub.3 CH.sub.3 H L-1bN N N O CH.sub.3 CH.sub.3 H L-1cN N N O CH.sub.3 CH.sub.3 H L-1dN N N O CH.sub.3 CH.sub.3 H L-1aN N N O CH.sub.3 CH.sub.3 H L-1fN N N O CH.sub.3 CH.sub.3 H L-1gN N N O CH.sub.3 CH.sub.3 H L-1hN N N O CH.sub.3 CH.sub.3 H L-1iN N N O CH.sub.3 CH.sub.3 H L-1jN N N O CH.sub.3 CH.sub.3 H L-1kN N N O CH.sub.3 CH.sub.3 H L-3aN N N O CH.sub.3 CH.sub.3 H L-3bN N N O CH.sub.3 CH.sub.3 H L-4aN N N O CH.sub.3 CH.sub.3 H L-7aN N N O CH.sub.3 CH.sub.3 H L-8aN N N O CH.sub.3 CH.sub.3 H L-8bN N N O CH.sub.3 CH.sub.3 H L-9aN N N O CH.sub.3 CH.sub.3 H L-12aN N N O CH.sub.3 CH.sub.3 H L-12bN N N O CH.sub.3 CH.sub.3 H L-14aN N N O CH.sub.3 CH.sub.3 H L-15aN N N O CH.sub.3 CH.sub.3 H L-16aN N N O CH.sub.3 CH.sub.3 H L-16bN N N O CH.sub.3 CH.sub.3 H L-18aN N N O CH.sub.3 CH.sub.3 H L-20aN N N O CH.sub.3 CH.sub.3 H L-22aN N N S CH.sub.3 CH.sub.3 H L-1aN N N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N N O OCH.sub.3 CH.sub.3 H L-1aN N N O OCH.sub.3 CH.sub.3 H L-1bN N N O OCH.sub.3 CH.sub.3 H L-1cN N N O OCH.sub.3 CH.sub.3 H L-1dN N N O OCH.sub.3 CH.sub.3 H L-1eN N N O OCH.sub.3 CH.sub.3 H L-1fN N N O OCH.sub.3 CH.sub.3 H L-1gN N N O OCH.sub.3 CH.sub.3 H L-1hN N N O OCH.sub.3 CH.sub.3 H L-1iN N N O OCH.sub.3 CH.sub.3 H L-1jN N N O OCH.sub.3 CH.sub.3 H L-1kN N N O OCH.sub.3 CH.sub.3 H L-3aN N N O OCH.sub.3 CH.sub.3 H L-3bN N N O OCH.sub.3 CH.sub.3 H L-4aN N N O OCH.sub.3 CH.sub.3 H L-7aN N N O OCH.sub.3 CH.sub.3 H L-8aN N N O OCH.sub.3 CH.sub.3 H L-8bN N N O OCH.sub. 3 CH.sub.3 H L-9aN N N O OCH.sub.3 CH.sub.3 H L-12aN N N O OCH.sub.3 CH.sub.3 H L-12bN N N O OCH.sub.3 CH.sub.3 H L-14aN N N O OCH.sub.3 CH.sub.3 H L-15aN N N O OCH.sub.3 CH.sub.3 H L-16aN N N O OCH.sub.3 CH.sub.3 H L-16bN N N O OCH.sub.3 CH.sub.3 H L-18aN N N O OCH.sub.3 CH.sub.3 H L-20aN N N O OCH.sub.3 CH.sub.3 H L-22aN N N S OCH.sub.3 CH.sub.3 H L-1aN N N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N N O CH.sub.3 OCH.sub.3 H L-1aN N N O CH.sub.3 OCH.sub.3 H L-1bN N N O CH.sub.3 OCH.sub.3 H L-1cN N N O CH.sub.3 OCH.sub.3 H L-1dN N N O CH.sub.3 OCH.sub.3 H L-1eN N N O CH.sub.3 OCH.sub.3 H L-1fN N N O CH.sub.3 OCH.sub.3 H L-1gN N N O CH.sub.3 OCH.sub.3 H L-1hN N N O CH.sub.3 OCH.sub.3 H L-1iN N N O CH.sub.3 OCH.sub.3 H L-1jN N N O CH.sub.3 OCH.sub.3 H L-1kN N N O CH.sub.3 OCH.sub.3 H L-3aN N N O CH.sub.3 OCH.sub.3 H L-3bN N N O CH.sub.3 OCH.sub.3 H L-4aN N N O CH.sub.3 OCH.sub.3 H L-7aN N N O CH.sub.3 OCH.sub.3 H L-8aN N N O CH.sub.3 OCH.sub.3 H L-8bN N N O CH.sub.3 OCH.sub.3 H L-9aN N N O CH.sub.3 OCH.sub.3 H L-12aN N N O CH.sub.3 OCH.sub.3 H L-12bN N N O CH.sub.3 OCH.sub.3 H L-14aN N N O CH.sub.3 OCH.sub.3 H L-15aN N N O CH.sub.3 OCH.sub.3 H L-16aN N N O CH.sub.3 OCH.sub.3 H L-16bN N N O CH.sub.3 OCH.sub.3 H L-18aN N N O CH.sub.3 OCH.sub.3 H L-20aN N N O CH.sub.3 OCH.sub.3 H L-22aN N N S CH.sub.3 OCH.sub.3 H L-1aN N N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N N O OCH.sub.3 OCH.sub.3 H L-1aN N N O OCH.sub.3 OCH.sub.3 H L-1bN N N O OCH.sub.3 OCH.sub.3 H L-1cN N N O OCH.sub.3 OCH.sub.3 H L-1dN N N O OCH.sub.3 OCH.sub.3 H L-1eN N N O OCH.sub.3 OCH.sub.3 H L-1fN N N O OCH.sub.3 OCH.sub.3 H L-1gN N N O OCH.sub.3 OCH.sub.3 H L-1hN N N O OCH.sub.3 OCH.sub.3 H L-1iN N N O OCH.sub.3 OCH.sub.3 H L-1jN N N O OCH.sub.3 OCH.sub.3 H L-1kN N N O OCH.sub.3 OCH.sub.3 H L-3aN N N O OCH.sub.3 OCH.sub.3 H L-3bN N N O OCH.sub.3 OCH.sub.3 H L-4aN N N O OCH.sub.3 OCH.sub.3 H L-7aN N N O OCH.sub.3 OCH.sub.3 H L-8aN N N O OCH.sub.3 OCH.sub.3 H L-8bN N N O OCH.sub.3 OCH.sub.3 H L-9aN N N O OCH.sub.3 OCH.sub.3 H L-12aN N N O OCH.sub.3 OCH.sub.3 H L-12bN N N O OCH.sub.3 OCH.sub.3 H L-14aN N N O OCH.sub.3 OCH.sub.3 H L-15aN N N O OCH.sub.3 OCH.sub.3 H L-16aN N N O OCH.sub.3 OCH.sub.3 H L-16bN N N O OCH.sub.3 OCH.sub.3 H L-18aN N N O OCH.sub.3 OCH.sub.3 H L-20aN N N O OCH.sub.3 OCH.sub.3 H L-22aN N N S OCH.sub.3 OCH.sub.3 H L-1aN N N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N O CH.sub.3 CH.sub.3 H L-1aN CH N O CH.sub.3 CH.sub.3 H L-1bN CH N O CH.sub.3 CH.sub.3 H L-1cN CH N O CH.sub.3 CH.sub.3 H L-1dN CH N O CH.sub.3 CH.sub.3 H L-1eN CH N O CH.sub.3 CH.sub.3 H L-1fN CH N O CH.sub.3 CH.sub.3 H L-1gN CH N O CH.sub.3 CH.sub.3 H L-1hN CH N O CH.sub.3 CH.sub.3 H L-1iN CH N O CH.sub.3 CH.sub.3 H L-1jN CH N O CH.sub.3 CH.sub.3 H L-1kN CH N O CH.sub.3 CH.sub.3 H L-3aN CH N O CH.sub.3 CH.sub.3 H L-3bN CH N O CH.sub.3 CH.sub.3 H L-4aN CH N O CH.sub.3 CH.sub.3 H L-7aN CH N O CH.sub.3 CH.sub.3 H L-8aN CH N O CH.sub.3 CH.sub.3 H L-8bN CH N O CH.sub.3 CH.sub.3 H L-9aN CH N O CH.sub.3 CH.sub.3 H L-12aN CH N O CH.sub.3 CH.sub.3 H L-12bN CH N O CH.sub.3 CH.sub.3 H L-14aN CH N O CH.sub.3 CH.sub.3 H L-15aN CH N O CH.sub.3 CH.sub.3 H L-16aN CH N O CH.sub.3 CH.sub.3 H L-16bN CH N O CH.sub.3 CH.sub.3 H L-18aN CH N O CH.sub.3 CH.sub.3 H L-20aN CH N O CH.sub.3 CH.sub.3 H L-22aN CH N S CH.sub.3 CH.sub.3 H L-1aN CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N O OCH.sub.3 CH.sub.3 H L-1aN CH N O OCH.sub.3 CH.sub.3 H L-1bN CH N O OCH.sub.3 CH.sub.3 H L-1cN CH N O OCH.sub.3 CH.sub.3 H L-1dN CH N O OCH.sub.3 CH.sub.3 H L-1eN CH N O OCH.sub.3 CH.sub.3 H L-1fN CH N O OCH.sub.3 CH.sub.3 H L-1gN CH N O OCH.sub.3 CH.sub.3 H L-1hN CH N O OCH.sub.3 CH.sub.3 H L-1iN CH N O OCH.sub.3 CH.sub.3 H L-1jN CH N O OCH.sub.3 CH.sub.3 H L-1kN CH N O OCH.sub.3 CH.sub.3 H L-3aN CH N O OCH.sub.3 CH.sub.3 H L-3bN CH N O OCH.sub.3 CH.sub.3 H L-4aN CH N O OCH.sub.3 CH.sub.3 H L-7aN CH N O OCH.sub.3 CH.sub.3 H L-8aN CH N O OCH.sub.3 CH.sub.3 H L-8bN CH N O OCH.sub.3 CH.sub.3 H L-9aN CH N O OCH.sub.3 CH.sub.3 H L-12aN CH N O OCH.sub.3 CH.sub.3 H L-12bN CH N O OCH.sub.3 CH.sub.3 H L-14aN CH N O OCH.sub.3 CH.sub.3 H L-15aN CH N O OCH.sub.3 CH.sub.3 H L-16aN CH N O OCH.sub.3 CH.sub.3 H L-16bN CH N O OCH.sub.3 CH.sub.3 H L-18aN CH N O OCH.sub.3 CH.sub.3 H L-20aN CH N O OCH.sub.3 CH.sub.3 H L-22aN CH N S OCH.sub.3 CH.sub.3 H L-1aN CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N O CH.sub.3 OCH.sub.3 H L-1aN CH N O CH.sub.3 OCH.sub.3 H L-1bN CH N O CH.sub.3 OCH.sub.3 H L-1cN CH N O CH.sub.3 OCH.sub.3 H L-1dN CH N O CH.sub.3 OCH.sub.3 H L-1eN CH N O CH.sub.3 OCH.sub.3 H L-1fN CH N O CH.sub.3 OCH.sub.3 H L-1gN CH N O CH.sub.3 OCH.sub.3 H L-1hN CH N O CH.sub.3 OCH.sub.3 H L-1iN CH N O CH.sub.3 OCH.sub.3 H L-1jN CH N O CH.sub.3 OCH.sub.3 H L-1kN CH N O CH.sub.3 OCH.sub.3 H L-3aN CH N O CH.sub.3 OCH.sub.3 H L-3bN CH N O CH.sub.3 OCH.sub.3 H L-4aN CH N O CH.sub.3 OCH.sub.3 H L-7aN CH N O CH.sub.3 OCH.sub.3 H L-8aN CH N O CH.sub.3 OCH.sub.3 H L-8bN CH N O CH.sub.3 OCH.sub.3 H L-9aN CH N O CH.sub.3 OCH.sub.3 H L-12aN CH N O CH.sub.3 OCH.sub.3 H L-12bN CH N O CH.sub.3 OCH.sub.3 H L-14aN CH N O CH.sub.3 OCH.sub.3 H L-15aN CH N O CH.sub.3 OCH.sub.3 H L-16aN CH N O CH.sub.3 OCH.sub.3 H L-16bN CH N O CH.sub.3 OCH.sub.3 H L-18aN CH N O CH.sub.3 OCH.sub.3 H L-20aN CH N O CH.sub.3 OCH.sub.3 H L-22aN CH N S CH.sub.3 OCH.sub.3 H L-1aN CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N O OCH.sub.3 OCH.sub.3 H L-1aN CH N O OCH.sub.3 OCH.sub.3 H L-1bN CH N O OCH.sub.3 OCH.sub.3 H L-1cN CH N O OCH.sub.3 OCH.sub.3 H L-1dN CH N O OCH.sub.3 OCH.sub.3 H L-1eN CH N O OCH.sub.3 OCH.sub.3 H L-1fN CH N O OCH.sub.3 OCH.sub.3 H L-1gN CH N O OCH.sub.3 OCH.sub.3 H L-1hN CH N O OCH.sub.3 OCH.sub.3 H L-1iN CH N O OCH.sub.3 OCH.sub.3 H L-1jN CH N O OCH.sub.3 OCH.sub.3 H L-1kN CH N O OCH.sub.3 OCH.sub.3 H L-3aN CH N O OCH.sub.3 OCH.sub.3 H L-3bN CH N O OCH.sub.3 OCH.sub.3 H L-4aN CH N O OCH.sub.3 OCH.sub.3 H L-7aN CH N O OCH.sub.3 OCH.sub.3 H L-8aN CH N O OCH.sub.3 OCH.sub.3 H L-8bN CH N O OCH.sub.3 OCH.sub.3 H L-9aN CH N O OCH.sub.3 OCH.sub.3 H L-12aN CH N O OCH.sub.3 OCH.sub.3 H L-12bN CH N O OCH.sub.3 OCH.sub.3 H L-14aN CH N O OCH.sub.3 OCH.sub.3 H L-15aN CH N O OCH.sub.3 OCH.sub.3 H L-16aN CH N O OCH.sub.3 OCH.sub.3 H L-16bN CH N O OCH.sub.3 OCH.sub.3 H L-18aN CH N O OCH.sub.3 OCH.sub.3 H L-20aN CH N O OCH.sub.3 OCH.sub.3 H L-22aN CH N S OCH.sub.3 OCH.sub.3 H L-1aN CH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH O CH.sub.3 CH.sub.3 H L-1aN CH CH O CH.sub.3 CH.sub.3 H L-1bN CH CH O CH.sub.3 CH.sub.3 H L-1cN CH CH O CH.sub.3 CH.sub.3 H L-1dN CH CH O CH.sub.3 CH.sub.3 H L-1eN CH CH O CH.sub.3 CH.sub.3 H L-1fN CH CH O CH.sub.3 CH.sub.3 H L-1gN CH CH O CH.sub.3 CH.sub.3 H L-1hN CH CH O CH.sub.3 CH.sub.3 H L-1iN CH CH O CH.sub.3 CH.sub.3 H L-1jN CH CH O CH.sub.3 CH.sub.3 H L-1kN CH CH O CH.sub.3 CH.sub.3 H L-3aN CH CH O CH.sub.3 CH.sub.3 H L-3bN CH CH O CH.sub.3 CH.sub.3 H L-4aN CH CH O CH.sub.3 CH.sub.3 H L-7aN CH CH O CH.sub.3 CH.sub.3 H L-8aN CH CH O CH.sub.3 CH.sub.3 H L-8bN CH CH O CH.sub.3 CH.sub.3 H L-9aN CH CH O CH.sub.3 CH.sub.3 H L-12aN CH CH O CH.sub.3 CH.sub.3 H L-12bN CH CH O CH.sub.3 CH.sub.3 H L-14aN CH CH O CH.sub.3 CH.sub.3 H L-15aN CH CH O CH.sub.3 CH.sub.3 H L-16aN CH CH O CH.sub.3 CH.sub.3 H L-16bN CH CH O CH.sub.3 CH.sub.3 H L-18aN CH CH O CH.sub.3 CH.sub.3 H L-20aN CH CH O CH.sub.3 CH.sub.3 H L-22aN CH CH S CH.sub.3 CH.sub.3 H L-1aN CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH O OCH.sub.3 CH.sub.3 H L-1aN CH CH O OCH.sub.3 CH.sub.3 H L-1bN CH CH O OCH.sub.3 CH.sub.3 H L-1cN CH CH O OCH.sub.3 CH.sub.3 H L-1dN CH CH O OCH.sub.3 CH.sub. 3 H L-1eN CH CH O OCH.sub.3 CH.sub.3 H L-1fN CH CH O OCH.sub.3 CH.sub.3 H L-1gN CH CH O OCH.sub.3 CH.sub.3 H L-1hN CH CH O OCH.sub.3 CH.sub.3 H L-1iN CH CH O OCH.sub.3 CH.sub.3 H L-1jN CH CH O OCH.sub.3 CH.sub.3 H L-1kN CH CH O OCH.sub.3 CH.sub.3 H L-3aN CH CH O OCH.sub.3 CH.sub.3 H L-3bN CH CH O OCH.sub.3 CH.sub.3 H L-4aN CH CH O OCH.sub.3 CH.sub.3 H L-7aN CH CH O OCH.sub.3 CH.sub.3 H L-8aN CH CH O OCH.sub.3 CH.sub.3 H L-8bN CH CH O OCH.sub.3 CH.sub.3 H L-9aN CH CH O OCH.sub.3 CH.sub.3 H L-12aN CH CH O OCH.sub.3 CH.sub.3 H L-12bN CH CH O OCH.sub.3 CH.sub.3 H L-14aN CH CH O OCH.sub.3 CH.sub.3 H L-15aN CH CH O OCH.sub.3 CH.sub.3 H L-16aN CH CH O OCH.sub.3 CH.sub.3 H L-16bN CH CH O OCH.sub.3 CH.sub. 3 H L-18aN CH CH O OCH.sub.3 CH.sub.3 H L-20aN CH CH O OCH.sub.3 CH.sub.3 H L-22aN CH CH S OCH.sub.3 CH.sub.3 H L-1aN CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH O CH.sub.3 OCH.sub.3 H L-1aN CH CH O CH.sub.3 OCH.sub.3 H L-1bN CH CH O CH.sub.3 OCH.sub.3 H L-1cN CH CH O CH.sub.3 OCH.sub.3 H L-1dN CH CH O CH.sub.3 OCH.sub.3 H L-1aN CH CH O CH.sub.3 OCH.sub.3 H L-1fN CH CH O CH.sub.3 OCH.sub.3 H L-1gN CH CH O CH.sub.3 OCH.sub.3 H L-1hN CH CH O CH.sub.3 OCH.sub.3 H L-1iN CH CH O CH.sub.3 OCH.sub.3 H L-1jN CH CH O CH.sub.3 OCH.sub.3 H L-1kN CH CH O CH.sub.3 OCH.sub.3 H L-3aN CH CH O CH.sub.3 OCH.sub.3 H L-3bN CH CH O CH.sub.3 OCH.sub.3 H L-4aN CH CH O CH.sub.3 OCH.sub.3 H L-7aN CH CH O CH.sub.3 OCH.sub.3 H L-8aN CH CH O CH.sub.3 OCH.sub.3 H L-8bN CH CH O CH.sub.3 OCH.sub.3 H L-9aN CH CH O CH.sub.3 OCH.sub.3 H L-12aN CH CH O CH.sub.3 OCH.sub.3 H L-12bN CH CH O CH.sub.3 OCH.sub.3 H L-14aN CH CH O CH.sub.3 OCH.sub.3 H L-15aN CH CH O CH.sub.3 OCH.sub.3 H L-16aN CH CH O CH.sub.3 OCH.sub.3 H L-16bN CH CH O CH.sub.3 OCH.sub.3 H L-18aN CH CH O CH.sub.3 OCH.sub.3 H L-20aN CH CH O CH.sub.3 OCH.sub.3 H L-22aN CH CH S CH.sub.3 OCH.sub.3 H L-1aN CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH O OCH.sub.3 OCH.sub.3 H L-1aN CH CH O OCH.sub.3 OCH.sub.3 H L-1bN CH CH O OCH.sub.3 OCH.sub.3 H L-1cN CH CH O OCH.sub.3 OCH.sub.3 H L-1dN CH CH O OCH.sub.3 OCH.sub.3 H L-1eN CH CH O OCH.sub.3 OCH.sub.3 H L-1fN CH CH O OCH.sub. 3 OCH.sub.3 H L-1gN CH CH O OCH.sub.3 OCH.sub.3 H L-1hN CH CH O OCH.sub.3 OCH.sub.3 H L-1iN CH CH O OCH.sub.3 OCH.sub.3 H L-1jN CH CH O OCH.sub.3 OCH.sub.3 H L-1kN CH CH O OCH.sub.3 OCH.sub.3 H L-3aN CH CH O OCH.sub.3 OCH.sub.3 H L-3bN CH CH O OCH.sub.3 OCH.sub.3 H L-4aN CH CH O OCH.sub.3 OCH.sub.3 H L-7aN CH CH O OCH.sub.3 OCH.sub.3 H L-8aN CH CH O OCH.sub.3 OCH.sub.3 H L-8bN CH CH O OCH.sub.3 OCH.sub.3 H L-9aN CH CH O OCH.sub.3 OCH.sub.3 H L-12aN CH CH O OCH.sub.3 OCH.sub.3 H L-12bN CH CH O OCH.sub.3 OCH.sub.3 H L-14aN CH CH O OCH.sub.3 OCH.sub.3 H L-15aN CH CH O OCH.sub.3 OCH.sub.3 H L-16aN CH CH O OCH.sub.3 OCH.sub.3 H L-16bN CH CH O OCH.sub.3 OCH.sub.3 H L-18aN CH CH O OCH.sub.3 OCH.sub.3 H L-20aN CH CH O OCH.sub. 3 OCH.sub.3 H L-22aN CH CH S OCH.sub.3 OCH.sub.3 H L-1aN CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1a______________________________________
TABLE 3______________________________________General Formula 3 m.p.Z Z.sub.1 Z.sub.2 W X Y R L (.degree.C.)______________________________________CH N CH O CH.sub.3 CH.sub.3 H L-1aCH N CH O CH.sub.3 CH.sub.3 H L-1bCH N CH O CH.sub.3 CH.sub.3 H L-1cCH N CH O CH.sub.3 CH.sub.3 H L-1dCH N CH O CH.sub.3 CH.sub.3 H L-1eCH N CH O CH.sub.3 CH.sub.3 H L-1fCH N CH O CH.sub.3 CH.sub.3 H L-1gCH N CH O CH.sub.3 CH.sub.3 H L-1hCH N CH O CH.sub.3 CH.sub.3 H L-1iCH N CH O CH.sub.3 CH.sub.3 H L-1jCH N CH O CH.sub.3 CH.sub.3 H L-1kCH N CH O CH.sub.3 CH.sub.3 H L-3aCH N CH O CH.sub.3 CH.sub.3 H L-3bCH N CH O CH.sub.3 CH.sub.3 H L-4aCH N CH O CH.sub.3 CH.sub.3 H L-7aCH N CH O CH.sub.3 CH.sub.3 H L-8aCH N CH O CH.sub.3 CH.sub.3 H L-8bCH N CH O CH.sub.3 CH.sub.3 H L-9aCH N CH O CH.sub.3 CH.sub.3 H L-12aCH N CH O CH.sub.3 CH.sub.3 H L-12bCH N CH O CH.sub.3 CH.sub.3 H L-14aCH N CH O CH.sub.3 CH.sub.3 H L-15aCH N CH O CH.sub.3 CH.sub.3 H L-16aCH N CH O CH.sub.3 CH.sub.3 H L-16bCH N CH O CH.sub.3 CH.sub.3 H L-18aCH N CH O CH.sub.3 CH.sub.3 H L-20aCH N CH O CH.sub.3 CH.sub.3 H L-22aCH N CH S CH.sub.3 CH.sub.3 H L-1aCH N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH O OCH.sub.3 CH.sub.3 H L-1aCH N CH O OCH.sub.3 CH.sub.3 H L-1bCH N CH O OCH.sub.3 CH.sub.3 H L-1cCH N CH O OCH.sub.3 CH.sub.3 H L-1dCH N CH O OCH.sub.3 CH.sub.3 H L-1eCH N CH O OCH.sub.3 CH.sub.3 H L-1fCH N CH O OCH.sub.3 CH.sub.3 H L-1gCH N CH O OCH.sub.3 CH.sub.3 H L-1hCH N CH O OCH.sub.3 CH.sub.3 H L-1iCH N CH O OCH.sub.3 CH.sub.3 H L-1jCH N CH O OCH.sub.3 CH.sub.3 H L-1kCH N CH O OCH.sub.3 CH.sub.3 H L-3aCH N CH O OCH.sub.3 CH.sub.3 H L-3bCH N CH O OCH.sub.3 CH.sub.3 H L-4aCH N CH O OCH.sub.3 CH.sub.3 H L-7aCH N CH O OCH.sub.3 CH.sub.3 H L-8aCH N CH O OCH.sub.3 CH.sub.3 H L-8bCH N CH O OCH.sub.3 CH.sub.3 H L-9aCH N CH O OCH.sub.3 CH.sub.3 H L-12aCH N CH O OCH.sub.3 CH.sub.3 H L-12bCH N CH O OCH.sub.3 CH.sub.3 H L-14aCH N CH O OCH.sub.3 CH.sub.3 H L-15aCH N CH O OCH.sub.3 CH.sub.3 H L-16aCH N CH O OCH.sub.3 CH.sub.3 H L-16bCH N CH O OCH.sub.3 CH.sub.3 H L-18aCH N CH O OCH.sub.3 CH.sub.3 H L-20aCH N CH O OCH.sub.3 CH.sub.3 H L-22aCH N CH S OCH.sub.3 CH.sub.3 H L-1aCH N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH O CH.sub.3 OCH.sub.3 H L-1aCH N CH O CH.sub.3 OCH.sub.3 H L-1bCH N CH O CH.sub.3 OCH.sub.3 H L-1cCH N CH O CH.sub.3 OCH.sub.3 H L-1dCH N CH O CH.sub.3 OCH.sub.3 H L-1eCH N CH O CH.sub.3 OCH.sub.3 H L-1fCH N CH O CH.sub.3 OCH.sub.3 H L-1gCH N CH O CH.sub.3 OCH.sub.3 H L-1hCH N CH O CH.sub.3 OCH.sub.3 H L-1iCH N CH O CH.sub.3 OCH.sub.3 H L-1jCH N CH O CH.sub.3 OCH.sub.3 H L-1kCH N CH O CH.sub.3 OCH.sub.3 H L-3aCH N CH O CH.sub.3 OCH.sub.3 H L-3bCH N CH O CH.sub.3 OCH.sub.3 H L-4aCH N CH O CH.sub.3 OCH.sub.3 H L-7aCH N CH O CH.sub.3 OCH.sub.3 H L-8aCH N CH O CH.sub.3 OCH.sub.3 H L-8bCH N CH O CH.sub.3 OCH.sub.3 H L-9aCH N CH O CH.sub.3 OCH.sub.3 H L-12aCH N CH O CH.sub.3 OCH.sub.3 H L-12bCH N CH O CH.sub.3 OCH.sub.3 H L-14aCH N CH O CH.sub.3 OCH.sub.3 H L-15aCH N CH O CH.sub.3 OCH.sub.3 H L-16aCH N CH O CH.sub.3 OCH.sub.3 H L-16bCH N CH O CH.sub.3 OCH.sub.3 H L-18aCH N CH O CH.sub.3 OCH.sub.3 H L-20aCH N CH O CH.sub.3 OCH.sub.3 H L-22aCH N CH S CH.sub.3 OCH.sub.3 H L-1aCH N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N CH O OCH.sub.3 OCH.sub.3 H L-1aCH N CH O OCH.sub.3 OCH.sub.3 H L-1bCH N CH O OCH.sub.3 OCH.sub.3 H L-1cCH N CH O OCH.sub.3 OCH.sub.3 H L-1dCH N CH O OCH.sub.3 OCH.sub.3 H L-1eCH N CH O OCH.sub.3 OCH.sub.3 H L-1fCH N CH O OCH.sub.3 OCH.sub.3 H L-1gCH N CH O OCH.sub.3 OCH.sub.3 H L-1hCH N CH O OCH.sub.3 OCH.sub.3 H L-1iCH N CH O OCH.sub.3 OCH.sub.3 H L-1jCH N CH O OCH.sub.3 OCH.sub.3 H L-1kCH N CH O OCH.sub.3 OCH.sub.3 H L-3aCH N CH O OCH.sub.3 OCH.sub.3 H L-3bCH N CH O OCH.sub.3 OCH.sub.3 H L-4aCH N CH O OCH.sub.3 OCH.sub.3 H L-7aCH N CH O OCH.sub.3 OCH.sub.3 H L-8aCH N CH O OCH.sub.3 OCH.sub.3 H L-8bCH N CH O OCH.sub.3 OCH.sub.3 H L-9aCH N CH O OCH.sub.3 OCH.sub.3 H L-12aCH N CH O OCH.sub.3 OCH.sub.3 H L-12bCH N CH O OCH.sub.3 OCH.sub.3 H L-14aCH N CH O OCH.sub.3 OCH.sub.3 H L-15aCH N CH O OCH.sub.3 OCH.sub.3 H L-16aCH N CH O OCH.sub.3 OCH.sub.3 H L-16bCH N CH O OCH.sub.3 OCH.sub.3 H L-18aCH N CH O OCH.sub.3 OCH.sub.3 H L-20aCH N CH O OCH.sub.3 OCH.sub.3 H L-22aCH N CH S OCH.sub.3 OCH.sub.3 H L-1aCH N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N O CH.sub.3 CH.sub.3 H L-1aCH CH N O CH.sub.3 CH.sub.3 H L-1bCH CH N O CH.sub.3 CH.sub.3 H L-1cCH CH N O CH.sub.3 CH.sub.3 H L-1dCH CH N O CH.sub.3 CH.sub.3 H L-1eCH CH N O CH.sub.3 CH.sub.3 H L-1fCH CH N O CH.sub.3 CH.sub.3 H L-1gCH CH N O CH.sub.3 CH.sub.3 H L-1hCH CH N O CH.sub.3 CH.sub.3 H L-1iCH CH N O CH.sub.3 CH.sub.3 H L-1jCH CH N O CH.sub.3 CH.sub.3 H L-1kCH CH N O CH.sub.3 CH.sub.3 H L-3aCH CH N O CH.sub.3 CH.sub.3 H L-3bCH CH N O CH.sub.3 CH.sub.3 H L-4aCH CH N O CH.sub.3 CH.sub.3 H L-7aCH CH N O CH.sub.3 CH.sub.3 H L-8aCH CH N O CH.sub.3 CH.sub.3 H L-8bCH CH N O CH.sub.3 CH.sub.3 H L-9aCH CH N O CH.sub.3 CH.sub. 3 H L-12aCH CH N O CH.sub.3 CH.sub.3 H L-12bCH CH N O CH.sub.3 CH.sub.3 H L-14aCH CH N O CH.sub.3 CH.sub.3 H L-15aCH CH N O CH.sub.3 CH.sub.3 H L-16aCH CH N O CH.sub.3 CH.sub.3 H L-16bCH CH N O CH.sub.3 CH.sub.3 H L-18aCH CH N O CH.sub.3 CH.sub.3 H L-20aCH CH N O CH.sub.3 CH.sub.3 H L-22aCH CH N S CH.sub.3 CH.sub.3 H L-1aCH CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N O CH.sub.3 Cl H L-1a 114-116CH CH N O CH.sub.3 Cl H L-1b 202-205 (d)CH CH N O CH.sub.3 Cl H L-1c 135(d)CH CH N O CH.sub.3 Cl H L-1n 177-180 (d)CH CH N O CH.sub.3 Cl H L-1p 88-94CH CH N O CH.sub.3 Cl H L-1x 94-96CH CH N O CH.sub.3 Cl H L-1y 142-145CH CH N O Cl H H L-1n 157-159CH CH N O Cl H H L-1b 178-180CH CH N O Cl H H L-1p 110-112CH CH N O Cl H H L-1c 140-145CH CH N O Cl H H L-1x 105-108N CH N O OCH.sub.3 H H L-1b 148-152 (d)N CH N O OCH.sub.3 H H L-1p 195-197CH CH N O OCH.sub.3 CH.sub.3 H L-1aCH CH N O OCH.sub.3 CH.sub.3 H L-1bCH CH N O OCH.sub.3 CH.sub.3 H L-1cCH CH N O OCH.sub.3 CH.sub.3 H L-1dCH CH N O OCH.sub.3 CH.sub.3 H L-1eCH CH N O OCH.sub.3 CH.sub.3 H L-1fCH CH N O OCH.sub.3 CH.sub.3 H L-1gCH CH N O OCH.sub.3 CH.sub.3 H L-1hCH CH N O OCH.sub.3 CH.sub.3 H L-1iCH CH N O OCH.sub.3 CH.sub.3 H L-1jCH CH N O OCH.sub.3 CH.sub.3 H L-1kCH CH N O OCH.sub.3 CH.sub.3 H L-3aCH CH N O OCH.sub.3 CH.sub.3 H L-3bCH CH N O OCH.sub.3 CH.sub.3 H L-4aCH CH N O OCH.sub.3 CH.sub.3 H L-7aCH CH N O OCH.sub.3 CH.sub.3 H L-8aCH CH N O OCH.sub.3 CH.sub.3 H L-8bCH CH N O OCH.sub.3 CH.sub.3 H L-9aCH CH N O OCH.sub.3 CH.sub.3 H L-12aCH CH N O OCH.sub.3 CH.sub.3 H L-12bCH CH N O OCH.sub.3 CH.sub.3 H L-14aCH CH N O OCH.sub.3 CH.sub.3 H L-15aCH CH N O OCH.sub.3 CH.sub.3 H L-16aCH CH N O OCH.sub.3 CH.sub.3 H L-16bCH CH N O OCH.sub.3 CH.sub.3 H L-18aCH CH N O OCH.sub.3 CH.sub.3 H L-20aCH CH N O OCH.sub.3 CH.sub.3 H L-22aCH CH N S OCH.sub.3 CH.sub.3 H L-1aCH CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N O CH.sub.3 OCH.sub.3 H L-1aCH CH N O CH.sub.3 OCH.sub.3 H L-1bCH CH N O CH.sub.3 OCH.sub.3 H L-1cCH CH N O CH.sub.3 OCH.sub.3 H L-1dCH CH N O CH.sub.3 OCH.sub.3 H L-1eCH CH N O CH.sub.3 OCH.sub.3 H L-1fCH CH N O CH.sub.3 OCH.sub.3 H L-1gCH CH N O CH.sub.3 OCH.sub.3 H L-1hCH CH N O CH.sub.3 OCH.sub.3 H L-1iCH CH N O CH.sub.3 OCH.sub.3 H L-1jCH CH N O CH.sub.3 OCH.sub.3 H L-1kCH CH N O CH.sub.3 OCH.sub.3 H L-3aCH CH N O CH.sub.3 OCH.sub.3 H L-3bCH CH N O CH.sub.3 OCH.sub.3 H L-4aCH CH N O CH.sub.3 OCH.sub.3 H L-7aCH CH N O CH.sub.3 OCH.sub.3 H L-8aCH CH N O CH.sub.3 OCH.sub.3 H L-8bCH CH N O CH.sub.3 OCH.sub.3 H L-9aCH CH N O CH.sub.3 OCH.sub.3 H L-12aCH CH N O CH.sub.3 OCH.sub.3 H L-12bCH CH N O CH.sub.3 OCH.sub.3 H L-14aCH CH N O CH.sub.3 OCH.sub.3 H L-15aCH CH N O CH.sub.3 OCH.sub.3 H L-16aCH CH N O CH.sub.3 OCH.sub.3 H L-16bCH CH N O CH.sub.3 OCH.sub.3 H L-18aCH CH N O CH.sub.3 OCH.sub.3 H L-20aCH CH N O CH.sub.3 OCH.sub.3 H L-22aCH CH N S CH.sub.3 OCH.sub.3 H L-1aCH CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N O OCH.sub.3 OCH.sub.3 H L-1aCH CH N O OCH.sub.3 OCH.sub.3 H L-1bCH CH N O OCH.sub.3 OCH.sub.3 H L-1cCH CH N O OCH.sub.3 OCH.sub.3 H L-1dCH CH N O OCH.sub.3 OCH.sub.3 H L-1eCH CH N O OCH.sub.3 OCH.sub.3 H L-1fCH CH N O OCH.sub.3 OCH.sub.3 H L-1gCH CH N O OCH.sub.3 OCH.sub.3 H L-1hCH CH N O OCH.sub.3 OCH.sub.3 H L-1iCH CH N O OCH.sub.3 OCH.sub.3 H L-1jCH CH N O OCH.sub.3 OCH.sub.3 H L-1kCH CH N O OCH.sub.3 OCH.sub.3 H L-3aCH CH N O OCH.sub.3 OCH.sub.3 H L-3bCH CH N O OCH.sub.3 OCH.sub.3 H L-4aCH CH N O OCH.sub.3 OCH.sub.3 H L-7aCH CH N O OCH.sub.3 OCH.sub.3 H L-8aCH CH N O OCH.sub.3 OCH.sub.3 H L-8bCH CH N O OCH.sub.3 OCH.sub.3 H L-9aCH CH N O OCH.sub.3 OCH.sub.3 H L-12aCH CH N O OCH.sub.3 OCH.sub.3 H L-12bCH CH N O OCH.sub.3 OCH.sub.3 H L-14aCH CH N O OCH.sub.3 OCH.sub.3 H L-15aCH CH N O OCH.sub.3 OCH.sub.3 H L-16aCH CH N O OCH.sub.3 OCH.sub.3 H L-16bCH CH N O OCH.sub.3 OCH.sub.3 H L-18aCH CH N O OCH.sub.3 OCH.sub.3 H L-20aCH CH N O OCH.sub.3 OCH.sub.3 H L-22aCH CH N S OCH.sub.3 OCH.sub.3 H L-1aCH CH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH O CH.sub.3 CH.sub.3 H L-1aCH CH CH O CH.sub.3 CH.sub.3 H L-1bCH CH CH O CH.sub.3 CH.sub.3 H L-1cCH CH CH O CH.sub.3 CH.sub.3 H L-1dCH CH CH O CH.sub.3 CH.sub.3 H L-1eCH CH CH O CH.sub.3 CH.sub.3 H L-1fCH CH CH O CH.sub.3 CH.sub.3 H L-1gCH CH CH O CH.sub.3 CH.sub.3 H L-1hCH CH CH O CH.sub.3 CH.sub.3 H L-1iCH CH CH O CH.sub.3 CH.sub.3 H L-1jCH CH CH O CH.sub.3 CH.sub.3 H L-1kCH CH CH O CH.sub.3 CH.sub.3 H L-3aCH CH CH O CH.sub.3 CH.sub.3 H L-3bCH CH CH O CH.sub.3 CH.sub.3 H L-4aCH CH CH O CH.sub.3 CH.sub.3 H L-7aCH CH CH O CH.sub.3 CH.sub.3 H L-8aCH CH CH O CH.sub.3 CH.sub.3 H L-8bCH CH CH O CH.sub.3 CH.sub.3 H L-9aCH CH CH O CH.sub.3 CH.sub.3 H L-12aCH CH CH O CH.sub.3 CH.sub.3 H L-12bCH CH CH O CH.sub.3 CH.sub.3 H L-14aCH CH CH O CH.sub.3 CH.sub.3 H L-15aCH CH CH O CH.sub.3 CH.sub.3 H L-16aCH CH CH O CH.sub.3 CH.sub.3 H L-16bCH CH CH O CH.sub.3 CH.sub.3 H L-18aCH CH CH O CH.sub.3 CH.sub.3 H L-20aCH CH CH O CH.sub.3 CH.sub.3 H L-22aCH CH CH S CH.sub.3 CH.sub.3 H L-1aCH CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH O OCH.sub.3 CH.sub.3 H L-1aCH CH CH O OCH.sub.3 CH.sub.3 H L-1bCH CH CH O OCH.sub.3 CH.sub.3 H L-1cCH CH CH O OCH.sub.3 CH.sub.3 H L-1dCH CH CH O OCH.sub.3 CH.sub.3 H L-1eCH CH CH O OCH.sub.3 CH.sub.3 H L-1fCH CH CH O OCH.sub.3 CH.sub.3 H L-1gCH CH CH O OCH.sub.3 CH.sub.3 H L-1hCH CH CH O OCH.sub.3 CH.sub.3 H L-1iCH CH CH O OCH.sub.3 CH.sub.3 H L-1jCH CH CH O OCH.sub.3 CH.sub.3 H L-1kCH CH CH O OCH.sub.3 CH.sub.3 H L-3aCH CH CH O OCH.sub.3 CH.sub.3 H L-3bCH CH CH O OCH.sub.3 CH.sub.3 H L-4aCH CH CH O OCH.sub.3 CH.sub.3 H L-7aCH CH CH O OCH.sub.3 CH.sub. 3 H L-8aCH CH CH O OCH.sub.3 CH.sub.3 H L-8bCH CH CH O OCH.sub.3 CH.sub.3 H L-9aCH CH CH O OCH.sub.3 CH.sub.3 H L-12aCH CH CH O OCH.sub.3 CH.sub.3 H L-12bCH CH CH O OCH.sub.3 CH.sub.3 H L-14aCH CH CH O OCH.sub.3 CH.sub.3 H L-15aCH CH CH O OCH.sub.3 CH.sub.3 H L-16aCH CH CH O OCH.sub.3 CH.sub.3 H L-16bCH CH CH O OCH.sub.3 CH.sub.3 H L-18aCH CH CH O OCH.sub.3 CH.sub.3 H L-20aCH CH CH O OCH.sub.3 CH.sub.3 H L-22aCH CH CH S OCH.sub.3 CH.sub.3 H L-1aCH CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH O CH.sub.3 OCH.sub.3 H L-1aCH CH CH O CH.sub.3 OCH.sub.3 H L-1bCH CH CH O CH.sub.3 OCH.sub.3 H L-1cCH CH CH O CH.sub.3 OCH.sub.3 H L-1dCH CH CH O CH.sub.3 OCH.sub.3 H L-1eCH CH CH O CH.sub.3 OCH.sub.3 H L-1fCH CH CH O CH.sub.3 OCH.sub.3 H L-1gCH CH CH O CH.sub.3 OCH.sub.3 H L-1hCH CH CH O CH.sub.3 OCH.sub.3 H L-1iCH CH CH O CH.sub.3 OCH.sub.3 H L-1jCH CH CH O CH.sub.3 OCH.sub.3 H L-1kCH CH CH O CH.sub.3 OCH.sub.3 H L-3aCH CH CH O CH.sub.3 OCH.sub.3 H L-3bCH CH CH O CH.sub.3 OCH.sub.3 H L-4aCH CH CH O CH.sub.3 OCH.sub.3 H L-7aCH CH CH O CH.sub.3 OCH.sub.3 H L-8aCH CH CH O CH.sub.3 OCH.sub.3 H L-8bCH CH CH O CH.sub.3 OCH.sub.3 H L-9aCH CH CH O CH.sub.3 OCH.sub.3 H L-12aCH CH CH O CH.sub.3 OCH.sub.3 H L-12bCH CH CH O CH.sub.3 OCH.sub.3 H L-14aCH CH CH O CH.sub.3 OCH.sub.3 H L-15aCH CH CH O CH.sub.3 OCH.sub.3 H L-16aCH CH CH O CH.sub.3 OCH.sub.3 H L-16bCH CH CH O CH.sub.3 OCH.sub.3 H L-18aCH CH CH O CH.sub.3 OCH.sub.3 H L-20aCH CH CH O CH.sub.3 OCH.sub.3 H L-22aCH CH CH S CH.sub.3 OCH.sub.3 H L-1aCH CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH O OCH.sub.3 OCH.sub.3 H L-1aCH CH CH O OCH.sub.3 OCH.sub.3 H L-1bCH CH CH O OCH.sub.3 OCH.sub.3 H L-1cCH CH CH O OCH.sub.3 OCH.sub.3 H L-1dCH CH CH O OCH.sub.3 OCH.sub.3 H L-1eCH CH CH O OCH.sub.3 OCH.sub.3 H L-1fCH CH CH O OCH.sub.3 OCH.sub.3 H L-1gCH CH CH O OCH.sub.3 OCH.sub.3 H L-1hCH CH CH O OCH.sub.3 OCH.sub.3 H L-1iCH CH CH O OCH.sub.3 OCH.sub.3 H L-1jCH CH CH O OCH.sub.3 OCH.sub.3 H L-1kCH CH CH O OCH.sub.3 OCH.sub.3 H L-3aCH CH CH O OCH.sub.3 OCH.sub.3 H L-3bCH CH CH O OCH.sub.3 OCH.sub.3 H L-4aCH CH CH O OCH.sub.3 OCH.sub.3 H L-7aCH CH CH O OCH.sub.3 OCH.sub.3 H L-8aCH CH CH O OCH.sub.3 OCH.sub.3 H L-8bCH CH CH O OCH.sub. 3 OCH.sub.3 H L-9aCH CH CH O OCH.sub.3 OCH.sub.3 H L-12aCH CH CH O OCH.sub.3 OCH.sub.3 H L-12bCH CH CH O OCH.sub.3 OCH.sub.3 H L-14aCH CH CH O OCH.sub.3 OCH.sub.3 H L-15aCH CH CH O OCH.sub.3 OCH.sub.3 H L-16aCH CH CH O OCH.sub.3 OCH.sub.3 H L-16bCH CH CH O OCH.sub.3 OCH.sub.3 H L-18aCH CH CH O OCH.sub.3 OCH.sub.3 H L-20aCH CH CH O OCH.sub.3 OCH.sub.3 H L-22aCH CH CH S OCH.sub.3 OCH.sub.3 H L-1aCH CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH O CH.sub.3 CH.sub.3 H L-1aN N CH O CH.sub.3 CH.sub.3 H L-1bN N CH O CH.sub.3 CH.sub.3 H L-1cN N CH O CH.sub.3 CH.sub.3 H L-1dN N CH O CH.sub.3 CH.sub.3 H L-1eN N CH O CH.sub.3 CH.sub.3 H L-1fN N CH O CH.sub.3 CH.sub.3 H L-1gN N CH O CH.sub.3 CH.sub.3 H L-1hN N CH O CH.sub.3 CH.sub.3 H L-1iN N CH O CH.sub.3 CH.sub.3 H L-1jN N CH O CH.sub.3 CH.sub.3 H L-1kN N CH O CH.sub.3 CH.sub.3 H L-3aN N CH O CH.sub.3 CH.sub.3 H L-3bN N CH O CH.sub.3 CH.sub.3 H L-4aN N CH O CH.sub.3 CH.sub.3 H L-7aN N CH O CH.sub.3 CH.sub.3 H L-8aN N CH O CH.sub.3 CH.sub.3 H L-8bN N CH O CH.sub.3 CH.sub.3 H L-9aN N CH O CH.sub.3 CH.sub.3 H L-12aN N CH O CH.sub.3 CH.sub.3 H L-12bN N CH O CH.sub.3 CH.sub.3 H L-14aN N CH O CH.sub.3 CH.sub.3 H L-15aN N CH O CH.sub.3 CH.sub.3 H L-16aN N CH O CH.sub.3 CH.sub.3 H L-16bN N CH O CH.sub.3 CH.sub.3 H L-18aN N CH O CH.sub.3 CH.sub.3 H L-20aN N CH O CH.sub.3 CH.sub.3 H L-22aN N CH S CH.sub.3 CH.sub.3 H L-1aN N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH O OCH.sub.3 CH.sub.3 H L-1aN N CH O OCH.sub.3 CH.sub.3 H L-1bN N CH O OCH.sub.3 CH.sub.3 H L-1cN N CH O OCH.sub.3 CH.sub.3 H L-1dN N CH O OCH.sub.3 CH.sub.3 H L-1eN N CH O OCH.sub.3 CH.sub.3 H L-1fN N CH O OCH.sub.3 CH.sub.3 H L-1gN N CH O OCH.sub.3 CH.sub.3 H L-1hN N CH O OCH.sub.3 CH.sub.3 H L-1iN N CH O OCH.sub.3 CH.sub.3 H L-1jN N CH O OCH.sub.3 CH.sub.3 H L-1kN N CH O OCH.sub.3 CH.sub.3 H L-3aN N CH O OCH.sub.3 CH.sub.3 H L-3bN N CH O OCH.sub.3 CH.sub.3 H L-4aN N CH O OCH.sub.3 CH.sub.3 H L-7aN N CH O OCH.sub.3 CH.sub.3 H L-8aN N CH O OCH.sub.3 CH.sub.3 H L-8bN N CH O OCH.sub.3 CH.sub.3 H L-9aN N CH O OCH.sub.3 CH.sub.3 H L-12aN N CH O OCH.sub.3 CH.sub.3 H L-12bN N CH O OCH.sub.3 CH.sub.3 H L-14aN N CH O OCH.sub.3 CH.sub.3 H L-15aN N CH O OCH.sub.3 CH.sub.3 H L-16aN N CH O OCH.sub.3 CH.sub.3 H L-16bN N CH O OCH.sub.3 CH.sub.3 H L-18aN N CH O OCH.sub.3 CH.sub.3 H L-20aN N CH O OCH.sub.3 CH.sub.3 H L-22aN N CH S OCH.sub.3 CH.sub.3 H L-1aN N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH O CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 H L-1bN N CH O CH.sub.3 OCH.sub.3 H L-1cN N CH O CH.sub.3 OCH.sub.3 H L-1dN N CH O CH.sub.3 OCH.sub.3 H L-1eN N CH O CH.sub.3 OCH.sub.3 H L-1fN N CH O CH.sub.3 OCH.sub.3 H L-1gN N CH O CH.sub.3 OCH.sub.3 H L-1hN N CH O CH.sub.3 OCH.sub.3 H L-1iN N CH O CH.sub.3 OCH.sub.3 H L-1jN N CH O CH.sub.3 OCH.sub.3 H L-1kN N CH O CH.sub.3 OCH.sub.3 H L-3aN N CH O CH.sub.3 OCH.sub.3 H L-3bN N CH O CH.sub.3 OCH.sub.3 H L-4aN N CH O CH.sub.3 OCH.sub.3 H L-7aN N CH O CH.sub.3 OCH.sub.3 H L-8aN N CH O CH.sub.3 OCH.sub.3 H L-8bN N CH O CH.sub.3 OCH.sub.3 H L-9aN N CH O CH.sub.3 OCH.sub.3 H L-12aN N CH O CH.sub.3 OCH.sub.3 H L-12bN N CH O CH.sub.3 OCH.sub.3 H L-14aN N CH O CH.sub.3 OCH.sub.3 H L-15aN N CH O CH.sub.3 OCH.sub.3 H L-16aN N CH O CH.sub.3 OCH.sub.3 H L-16bN N CH O CH.sub.3 OCH.sub.3 H L-18aN N CH O CH.sub.3 OCH.sub.3 H L-20aN N CH O CH.sub.3 OCH.sub.3 H L-22aN N CH S CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH O OCH.sub.3 OCH.sub.3 H L-1aN N CH O OCH.sub.3 OCH.sub.3 H L-1bN N CH O OCH.sub.3 OCH.sub.3 H L-1cN N CH O OCH.sub.3 OCH.sub.3 H L-1dN N CH O OCH.sub.3 OCH.sub.3 H L-1eN N CH O OCH.sub.3 OCH.sub.3 H L-1fN N CH O OCH.sub.3 OCH.sub.3 H L-1gN N CH O OCH.sub.3 OCH.sub.3 H L-1hN N CH O OCH.sub.3 OCH.sub.3 H L-1iN N CH O OCH.sub.3 OCH.sub.3 H L-1jN N CH O OCH.sub.3 OCH.sub.3 H L-1kN N CH O OCH.sub.3 OCH.sub.3 H L-3aN N CH O OCH.sub.3 OCH.sub.3 H L-3bN N CH O OCH.sub.3 OCH.sub.3 H L-4aN N CH O OCH.sub.3 OCH.sub.3 H L-7aN N CH O OCH.sub.3 OCH.sub.3 H L-8aN N CH O OCH.sub.3 OCH.sub.3 H L-8bN N CH O OCH.sub.3 OCH.sub.3 H L-9aN N CH O OCH.sub.3 OCH.sub.3 H L-12aN N CH O OCH.sub.3 OCH.sub.3 H L-12bN N CH O OCH.sub.3 OCH.sub.3 H L-14aN N CH O OCH.sub.3 OCH.sub.3 H L-15aN N CH O OCH.sub.3 OCH.sub.3 H L-16aN N CH O OCH.sub.3 OCH.sub.3 H L-16bN N CH O OCH.sub.3 OCH.sub.3 H L-18aN N CH O OCH.sub.3 OCH.sub.3 H L-20aN N CH O OCH.sub.3 OCH.sub.3 H L-22aN N CH S OCH.sub.3 OCH.sub.3 H L-1aN N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N O CH.sub.3 CH.sub.3 H L-1aN CH N O CH.sub.3 CH.sub.3 H L-1bN CH N O CH.sub.3 CH.sub.3 H L-1cN CH N O CH.sub.3 CH.sub.3 H L-1dN CH N O CH.sub.3 CH.sub.3 H L-1eN CH N O CH.sub.3 CH.sub.3 H L-1fN CH N O CH.sub.3 CH.sub.3 H L-1gN CH N O CH.sub.3 CH.sub.3 H L-1hN CH N O CH.sub.3 CH.sub.3 H L-1iN CH N O CH.sub.3 CH.sub.3 H L-1jN CH N O CH.sub.3 CH.sub.3 H L-1kN CH N O CH.sub.3 CH.sub.3 H L-3aN CH N O CH.sub.3 CH.sub.3 H L-3bN CH N O CH.sub.3 CH.sub.3 H L-4aN CH N O CH.sub.3 CH.sub.3 H L-7aN CH N O CH.sub.3 CH.sub.3 H L-8aN CH N O CH.sub.3 CH.sub.3 H L-8bN CH N O CH.sub.3 CH.sub.3 H L-9aN CH N O CH.sub.3 CH.sub.3 H L-12aN CH N O CH.sub.3 CH.sub.3 H L-12bN CH N O CH.sub.3 CH.sub.3 H L-14aN CH N O CH.sub.3 CH.sub.3 H L-15aN CH N O CH.sub.3 CH.sub.3 H L-16aN CH N O CH.sub.3 CH.sub.3 H L-16bN CH N O CH.sub.3 CH.sub.3 H L-18aN CH N O CH.sub.3 CH.sub.3 H L-20aN CH N O CH.sub.3 CH.sub.3 H L-22aN CH N S CH.sub.3 CH.sub.3 H L-1aN CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N O OCH.sub.3 CH.sub.3 H L-1aN CH N O OCH.sub.3 CH.sub.3 H L-1bN CH N O OCH.sub.3 CH.sub.3 H L-1cN CH N O OCH.sub.3 CH.sub.3 H L-1dN CH N O OCH.sub.3 CH.sub.3 H L-1eN CH N O OCH.sub.3 CH.sub.3 H L-1fN CH N O OCH.sub.3 CH.sub.3 H L-1gN CH N O OCH.sub.3 CH.sub.3 H L-1hN CH N O OCH.sub.3 CH.sub.3 H L-1iN CH N O OCH.sub.3 CH.sub.3 H L-1jN CH N O OCH.sub.3 CH.sub.3 H L-1kN CH N O OCH.sub.3 CH.sub.3 H L-3aN CH N O OCH.sub.3 CH.sub.3 H L-3bN CH N O OCH.sub.3 CH.sub.3 H L-4aN CH N O OCH.sub.3 CH.sub.3 H L-7aN CH N O OCH.sub.3 CH.sub.3 H L-8aN CH N O OCH.sub.3 CH.sub.3 H L-8bN CH N O OCH.sub.3 CH.sub.3 H L-9aN CH N O OCH.sub.3 CH.sub.3 H L-12aN CH N O OCH.sub.3 CH.sub.3 H L-12bN CH N O OCH.sub.3 CH.sub.3 H L-14aN CH N O OCH.sub.3 CH.sub.3 H L-15aN CH N O OCH.sub.3 CH.sub.3 H L-16aN CH N O OCH.sub.3 CH.sub.3 H L-16bN CH N O OCH.sub.3 CH.sub.3 H L-18aN CH N O OCH.sub.3 CH.sub.3 H L-20aN CH N O OCH.sub.3 CH.sub.3 H L-22aN CH N S OCH.sub.3 CH.sub.3 H L-1aN CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N O CH.sub.3 OCH.sub.3 H L-1aN CH N O CH.sub.3 OCH.sub.3 H L-1bN CH N O CH.sub.3 OCH.sub.3 H L-1cN CH N O CH.sub.3 OCH.sub.3 H L-1dN CH N O CH.sub.3 OCH.sub.3 H L-1eN CH N O CH.sub.3 OCH.sub.3 H L-1fN CH N O CH.sub.3 OCH.sub.3 H L-1gN CH N O CH.sub.3 OCH.sub.3 H L-1hN CH N O CH.sub.3 OCH.sub.3 H L-1iN CH N O CH.sub.3 OCH.sub.3 H L-1jN CH N O CH.sub.3 OCH.sub.3 H L-1kN CH N O CH.sub.3 OCH.sub.3 H L-3aN CH N O CH.sub.3 OCH.sub.3 H L-3bN CH N O CH.sub.3 OCH.sub.3 H L-4aN CH N O CH.sub.3 OCH.sub.3 H L-7aN CH N O CH.sub.3 OCH.sub.3 H L-8aN CH N O CH.sub.3 OCH.sub.3 H L-8bN CH N O CH.sub.3 OCH.sub.3 H L-9aN CH N O CH.sub.3 OCH.sub.3 H L-12aN CH N O CH.sub.3 OCH.sub.3 H L-12bN CH N O CH.sub.3 OCH.sub.3 H L-14aN CH N O CH.sub.3 OCH.sub.3 H L-15aN CH N O CH.sub.3 OCH.sub.3 H L-16aN CH N O CH.sub.3 OCH.sub.3 H L-16bN CH N O CH.sub.3 OCH.sub.3 H L-18aN CH N O CH.sub.3 OCH.sub.3 H L-20aN CH N O CH.sub.3 OCH.sub.3 H L-22aN CH N S CH.sub.3 OCH.sub.3 H L-1aN CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N O OCH.sub.3 OCH.sub.3 H L-1aN CH N O OCH.sub.3 OCH.sub.3 H L-1bN CH N O OCH.sub.3 OCH.sub.3 H L-1cN CH N O OCH.sub.3 OCH.sub.3 H L-1dN CH N O OCH.sub.3 OCH.sub. 3 H L-1eN CH N O OCH.sub.3 OCH.sub.3 H L-1fN CH N O OCH.sub.3 OCH.sub.3 H L-1gN CH N O OCH.sub.3 OCH.sub.3 H L-1hN CH N O OCH.sub.3 OCH.sub.3 H L-1iN CH N O OCH.sub.3 OCH.sub.3 H L-1jN CH N O OCH.sub.3 OCH.sub.3 H L-1kN CH N O OCH.sub.3 OCH.sub.3 H L-3aN CH N O OCH.sub.3 OCH.sub.3 H L-3bN CH N O OCH.sub.3 OCH.sub.3 H L-4aN CH N O OCH.sub.3 OCH.sub.3 H L-7aN CH N O OCH.sub.3 OCH.sub.3 H L-8aN CH N O OCH.sub.3 OCH.sub.3 H L-8bN CH N O OCH.sub.3 OCH.sub.3 H L-9aN CH N O OCH.sub.3 OCH.sub.3 H L-12aN CH N O OCH.sub.3 OCH.sub.3 H L-12bN CH N O OCH.sub.3 OCH.sub.3 H L-14aN CH N O OCH.sub.3 OCH.sub.3 H L-15aN CH N O OCH.sub.3 OCH.sub.3 H L-16aN CH N O OCH.sub.3 OCH.sub.3 H L-16bN CH N O OCH.sub.3 OCH.sub. 3 H L-18aN CH N O OCH.sub.3 OCH.sub.3 H L-20aN CH N O OCH.sub.3 OCH.sub.3 H L-22aN CH N S OCH.sub.3 OCH.sub.3 H L-1aN CH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH O CH.sub.3 CH.sub.3 H L-1aN CH CH O CH.sub.3 CH.sub.3 H L-1bN CH CH O CH.sub.3 CH.sub.3 H L-1cN CH CH O CH.sub.3 CH.sub.3 H L-1dN CH CH O CH.sub.3 CH.sub.3 H L-1eN CH CH O CH.sub.3 CH.sub.3 H L-1fN CH CH O CH.sub.3 CH.sub.3 H L-1gN CH CH O CH.sub.3 CH.sub.3 H L-1hN CH CH O CH.sub.3 CH.sub.3 H L-1iN CH CH O CH.sub.3 CH.sub.3 H L-1jN CH CH O CH.sub.3 CH.sub.3 H L-1kN CH CH O CH.sub.3 CH.sub.3 H L-3aN CH CH O CH.sub.3 CH.sub.3 H L-3bN CH CH O CH.sub.3 CH.sub.3 H L-4aN CH CH O CH.sub.3 CH.sub.3 H L-7aN CH CH O CH.sub.3 CH.sub.3 H L-8aN CH CH O CH.sub.3 CH.sub.3 H L-8bN CH CH O CH.sub.3 CH.sub.3 H L-9aN CH CH O CH.sub.3 CH.sub.3 H L-12aN CH CH O CH.sub.3 CH.sub.3 H L-12bN CH CH O CH.sub.3 CH.sub.3 H L-14aN CH CH O CH.sub.3 CH.sub.3 H L-15aN CH CH O CH.sub.3 CH.sub.3 H L-16aN CH CH O CH.sub.3 CH.sub.3 H L-16bN CH CH O CH.sub.3 CH.sub.3 H L-18aN CH CH O CH.sub.3 CH.sub.3 H L-20aN CH CH O CH.sub.3 CH.sub.3 H L-22aN CH CH S CH.sub.3 CH.sub.3 H L-1aN CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH O OCH.sub.3 CH.sub.3 H L-1aN CH CH O OCH.sub.3 CH.sub.3 H L-1bN CH CH O OCH.sub.3 CH.sub.3 H L-1cN CH CH O OCH.sub.3 CH.sub.3 H L-1dN CH CH O OCH.sub.3 CH.sub.3 H L-1eN CH CH O OCH.sub.3 CH.sub.3 H L-1fN CH CH O OCH.sub. 3 CH.sub.3 H L-1gN CH CH O OCH.sub.3 CH.sub.3 H L-1hN CH CH O OCH.sub.3 CH.sub.3 H L-1iN CH CH O OCH.sub.3 CH.sub.3 H L-1jN CH CH O OCH.sub.3 CH.sub.3 H L-1kN CH CH O OCH.sub.3 CH.sub.3 H L-3aN CH CH O OCH.sub.3 CH.sub.3 H L-3bN CH CH O OCH.sub.3 CH.sub.3 H L-4aN CH CH O OCH.sub.3 CH.sub.3 H L-7aN CH CH O OCH.sub.3 CH.sub.3 H L-8aN CH CH O OCH.sub.3 CH.sub.3 H L-8bN CH CH O OCH.sub.3 CH.sub.3 H L-9aN CH CH O OCH.sub.3 CH.sub.3 H L-12aN CH CH O OCH.sub.3 CH.sub.3 H L-12bN CH CH O OCH.sub.3 CH.sub.3 H L-14aN CH CH O OCH.sub.3 CH.sub.3 H L-15aN CH CH O OCH.sub.3 CH.sub.3 H L-16aN CH CH O OCH.sub.3 CH.sub.3 H L-16bN CH CH O OCH.sub.3 CH.sub.3 H L-18aN CH CH O OCH.sub.3 CH.sub.3 H L-20aN CH CH O OCH.sub. 3 CH.sub.3 H L-22aN CH CH S OCH.sub.3 CH.sub.3 H L-1aN CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH O CH.sub.3 OCH.sub.3 H L-1aN CH CH O CH.sub.3 OCH.sub.3 H L-1bN CH CH O CH.sub.3 OCH.sub.3 H L-1cN CH CH O CH.sub.3 OCH.sub.3 H L-1dN CH CH O CH.sub.3 OCH.sub.3 H L-1eN CH CH O CH.sub.3 OCH.sub.3 H L-1fN CH CH O CH.sub.3 OCH.sub.3 H L-1gN CH CH O CH.sub.3 OCH.sub.3 H L-1hN CH CH O CH.sub.3 OCH.sub.3 H L-1iN CH CH O CH.sub.3 OCH.sub.3 H L-1jN CH CH O CH.sub.3 OCH.sub.3 H L-1kN CH CH O CH.sub.3 OCH.sub.3 H L-3aN CH CH O CH.sub.3 OCH.sub.3 H L-3bN CH CH O CH.sub.3 OCH.sub.3 H L-4aN CH CH O CH.sub.3 OCH.sub.3 H L-7aN CH CH O CH.sub.3 OCH.sub.3 H L-8aN CH CH O CH.sub.3 OCH.sub.3 H L-8bN CH CH O CH.sub.3 OCH.sub.3 H L-9aN CH CH O CH.sub.3 OCH.sub.3 H L-12aN CH CH O CH.sub.3 OCH.sub.3 H L-12bN CH CH O CH.sub.3 OCH.sub.3 H L-14aN CH CH O CH.sub.3 OCH.sub.3 H L-15aN CH CH O CH.sub.3 OCH.sub.3 H L-16aN CH CH O CH.sub.3 OCH.sub.3 H L-16bN CH CH O CH.sub.3 OCH.sub.3 H L-18aN CH CH O CH.sub.3 OCH.sub.3 H L-20aN CH CH O CH.sub.3 OCH.sub.3 H L-22aN CH CH S CH.sub.3 OCH.sub.3 H L-1aN CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH O OCH.sub.3 OCH.sub.3 H L-1aN CH CH O OCH.sub.3 OCH.sub.3 H L-1bN CH CH O OCH.sub.3 OCH.sub.3 H L-1cN CH CH O OCH.sub.3 OCH.sub.3 H L-1dN CH CH O OCH.sub.3 OCH.sub.3 H L-1eN CH CH O OCH.sub.3 OCH.sub.3 H L-1fN CH CH O OCH.sub.3 OCH.sub.3 H L-1gN CH CH O OCH.sub.3 OCH.sub.3 H L-1hN CH CH O OCH.sub.3 OCH.sub.3 H L-1iN CH CH O OCH.sub.3 OCH.sub.3 H L-1jN CH CH O OCH.sub.3 OCH.sub.3 H L-1kN CH CH O OCH.sub.3 OCH.sub.3 H L-3aN CH CH O OCH.sub.3 OCH.sub.3 H L-3bN CH CH O OCH.sub.3 OCH.sub.3 H L-4aN CH CH O OCH.sub.3 OCH.sub.3 H L-7aN CH CH O OCH.sub.3 OCH.sub.3 H L-8aN CH CH O OCH.sub.3 OCH.sub.3 H L-8bN CH CH O OCH.sub.3 OCH.sub.3 H L-9aN CH CH O OCH.sub.3 OCH.sub.3 H L-12aN CH CH O OCH.sub.3 OCH.sub.3 H L-12bN CH CH O OCH.sub.3 OCH.sub.3 H L-14aN CH CH O OCH.sub.3 OCH.sub.3 H L-15aN CH CH O OCH.sub.3 OCH.sub.3 H L-16aN CH CH O OCH.sub.3 OCH.sub.3 H L-16bN CH CH O OCH.sub.3 OCH.sub.3 H L-18aN CH CH O OCH.sub.3 OCH.sub.3 H L-20aN CH CH O OCH.sub.3 OCH.sub.3 H L-22aN CH CH S OCH.sub.3 OCH.sub.3 H L-1aN CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1a______________________________________
TABLE 4______________________________________General Forula 4 m.p.Z Z.sub.1 Z.sub.4 W X Y R L (.degree.C.)______________________________________CH CH S O CH.sub.3 CH.sub.3 H L-1aCH CH S O CH.sub.3 CH.sub.3 H L-1bCH CH S O CH.sub.3 CH.sub.3 H L-1cCH CH S O CH.sub.3 CH.sub.3 H L-1dCH CH S O CH.sub.3 CH.sub.3 H L-1eCH CH S O CH.sub.3 CH.sub.3 H L-1fCH CH S O CH.sub.3 CH.sub.3 H L-1gCH CH S O CH.sub.3 CH.sub.3 H L-1hCH CH S O CH.sub.3 CH.sub.3 H L-1iCH CH S O CH.sub.3 CH.sub.3 H L-1jCH CH S O CH.sub.3 CH.sub.3 H L-1kCH CH S O CH.sub.3 CH.sub.3 H L-3aCH CH S O CH.sub.3 CH.sub.3 H L-3bCH CH S O CH.sub.3 CH.sub.3 H L-4aCH CH S O CH.sub.3 CH.sub.3 H L-7aCH CH S O CH.sub.3 CH.sub.3 H L-8aCH CH S O CH.sub.3 CH.sub.3 H L-8bCH CH S O CH.sub.3 CH.sub.3 H L-9aCH CH S O CH.sub.3 CH.sub.3 H L-12aCH CH S O CH.sub.3 CH.sub.3 H L-12bCH CH S O CH.sub.3 CH.sub.3 H L-14aCH CH S O CH.sub.3 CH.sub.3 H L-15aCH CH S O CH.sub.3 CH.sub.3 H L-16aCH CH S O CH.sub.3 CH.sub.3 H L-16bCH CH S O CH.sub.3 CH.sub.3 H L-18aCH CH S O CH.sub.3 CH.sub.3 H L-20aCH CH S O CH.sub.3 CH.sub.3 H L-22aCH CH S S CH.sub.3 CH.sub.3 H L-1aCH CH S O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH S O OCH.sub.3 CH.sub.3 H L-1aCH CH S O OCH.sub.3 CH.sub.3 H L-1bCH CH S O OCH.sub.3 CH.sub.3 H L-1cCH CH S O OCH.sub.3 CH.sub.3 H L-1dCH CH S O OCH.sub.3 CH.sub.3 H L-1eCH CH S O OCH.sub.3 CH.sub.3 H L-1fCH CH S O OCH.sub.3 CH.sub.3 H L-1gCH CH S O OCH.sub.3 CH.sub.3 H L-1hCH CH S O OCH.sub.3 CH.sub.3 H L-1iCH CH S O OCH.sub.3 CH.sub.3 H L-1jCH CH S O OCH.sub.3 CH.sub.3 H L-1kCH CH S O OCH.sub.3 CH.sub.3 H L-3aCH CH S O OCH.sub.3 CH.sub.3 H L-3bCH CH S O OCH.sub.3 CH.sub.3 H L-4aCH CH S O OCH.sub.3 CH.sub.3 H L-7aCH CH S O OCH.sub.3 CH.sub.3 H L-8aCH CH S O OCH.sub.3 CH.sub.3 H L-8bCH CH S O OCH.sub.3 CH.sub.3 H L-9aCH CH S O OCH.sub.3 CH.sub.3 H L-12aCH CH S O OCH.sub.3 CH.sub.3 H L-12bCH CH S O OCH.sub.3 CH.sub.3 H L-14aCH CH S O OCH.sub.3 CH.sub.3 H L-15aCH CH S O OCH.sub.3 CH.sub.3 H L-16aCH CH S O OCH.sub.3 CH.sub.3 H L-16bCH CH S O OCH.sub.3 CH.sub.3 H L-18aCH CH S O OCH.sub.3 CH.sub.3 H L-20aCH CH S O OCH.sub.3 CH.sub.3 H L-22aCH CH S S OCH.sub.3 CH.sub.3 H L-1aCH CH S O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH S O CH.sub.3 OCH.sub.3 H L-1aCH CH S O CH.sub.3 OCH.sub.3 H L-1bCH CH S O CH.sub.3 OCH.sub.3 H L-1cCH CH S O CH.sub.3 OCH.sub.3 H L-1dCH CH S O CH.sub.3 OCH.sub.3 H L-1eCH CH S O CH.sub.3 OCH.sub.3 H L-1fCH CH S O CH.sub.3 OCH.sub.3 H L-1gCH CH S O CH.sub.3 OCH.sub.3 H L-1hCH CH S O CH.sub.3 OCH.sub.3 H L-1iCH CH S O CH.sub.3 OCH.sub.3 H L-1jCH CH S O CH.sub.3 OCH.sub.3 H L-1kCH CH S O CH.sub.3 OCH.sub.3 H L-3aCH CH S O CH.sub.3 OCH.sub.3 H L-3bCH CH S O CH.sub.3 OCH.sub.3 H L-4aCH CH S O CH.sub.3 OCH.sub.3 H L-7aCH CH S O CH.sub.3 OCH.sub.3 H L-8aCH CH S O CH.sub.3 OCH.sub.3 H L-8bCH CH S O CH.sub.3 OCH.sub.3 H L-9aCH CH S O CH.sub.3 OCH.sub.3 H L-12aCH CH S O CH.sub.3 OCH.sub.3 H L-12bCH CH S O CH.sub.3 OCH.sub.3 H L-14aCH CH S O CH.sub.3 OCH.sub.3 H L-15aCH CH S O CH.sub.3 OCH.sub.3 H L-16aCH CH S O CH.sub.3 OCH.sub.3 H L-16bCH CH S O CH.sub.3 OCH.sub.3 H L-18aCH CH S O CH.sub.3 OCH.sub.3 H L-20aCH CH S O CH.sub.3 OCH.sub.3 H L-22aCH CH S S CH.sub.3 OCH.sub.3 H L-1aCH CH S O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH S O OCH.sub.3 OCH.sub.3 H L-1aCH CH S O OCH.sub.3 OCH.sub.3 H L-1bCH CH S O OCH.sub.3 OCH.sub.3 H L-1cCH CH S O OCH.sub.3 OCH.sub.3 H L-1dCH CH S O OCH.sub.3 OCH.sub.3 H L-1eCH CH S O OCH.sub.3 OCH.sub.3 H L-1fCH CH S O OCH.sub.3 OCH.sub.3 H L-1gCH CH S O OCH.sub.3 OCH.sub.3 H L-1hCH CH S O OCH.sub.3 OCH.sub.3 H L-1iCH CH S O OCH.sub.3 OCH.sub.3 H L-1jCH CH S O OCH.sub.3 OCH.sub.3 H L-1gCH CH S O OCH.sub.3 OCH.sub.3 H L-3aCH CH S O OCH.sub.3 OCH.sub.3 H L-3bCH CH S O OCH.sub.3 OCH.sub.3 H L-4aCH CH S O OCH.sub.3 OCH.sub.3 H L-7aCH CH S O OCH.sub.3 OCH.sub.3 H L-8aCH CH S O OCH.sub.3 OCH.sub.3 H L-8bCH CH S O OCH.sub.3 OCH.sub.3 H L-9aCH CH S O OCH.sub.3 OCH.sub.3 H L-12aCH CH S O OCH.sub.3 OCH.sub.3 H L-12bCH CH S O OCH.sub.3 OCH.sub.3 H L-14aCH CH S O OCH.sub.3 OCH.sub.3 H L-15aCH CH S O OCH.sub.3 OCH.sub.3 H L-16aCH CH S O OCH.sub.3 OCH.sub.3 H L-16bCH CH S O OCH.sub.3 OCH.sub.3 H L-18aCH CH S O OCH.sub.3 OCH.sub.3 H L-20aCH CH S O OCH.sub.3 OCH.sub.3 H L-22aCH CH S S OCH.sub.3 OCH.sub.3 H L-1aCH CH S O OCH.sub.3 OCH.sub.3 CH L-1aCH CH O O CH.sub.3 CH.sub.3 H L-1aCH CH O O CH.sub.3 CH.sub.3 H L-1cCH CH O O CH.sub.3 CH.sub.3 H L-1cCH CH O O CH.sub.3 CH.sub.3 H L-1dCH CH O O CH.sub.3 CH.sub.3 H L-1eCH CH O O CH.sub.3 CH.sub.3 H L-1fCH CH O O CH.sub.3 CH.sub.3 H L-1gCH CH O O CH.sub.3 CH.sub.3 H L-1hCH CH O O CH.sub.3 CH.sub.3 H L-1iCH CH O O CH.sub.3 CH.sub.3 H L-1jCH CH O O CH.sub.3 CH.sub.3 H L-1kCH CH O O CH.sub.3 CH.sub.3 H L-3aCH CH O O CH.sub.3 CH.sub.3 H L-3bCH CH O O CH.sub.3 CH.sub.3 H L-4aCH CH O O CH.sub.3 CH.sub.3 H L-7aCH CH O O CH.sub.3 CH.sub.3 H L-8aCH CH O O CH.sub.3 CH.sub.3 H L-8bCH CH O O CH.sub.3 CH.sub.3 H L-9aCH CH O O CH.sub.3 CH.sub.3 H L-12aCH CH O O CH.sub.3 CH.sub.3 H L-12bCH CH O O CH.sub.3 CH.sub.3 H L-14aCH CH O O CH.sub.3 CH.sub.3 H L-15aCH CH O O CH.sub.3 CH.sub.3 H L-16aCH CH O O CH.sub.3 CH.sub.3 H L-16bCH CH O O CH.sub.3 CH.sub.3 H L-18aCH CH O O CH.sub.3 CH.sub.3 H L-20aCH CH O O CH.sub.3 CH.sub.3 H L-22aCH CH O S CH.sub.3 CH.sub.3 H L-1aCH CH O O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH O O OCH.sub.3 CH.sub.3 H L-1aCH CH O O OCH.sub.3 CH.sub.3 H L-1bCH CH O O OCH.sub.3 CH.sub.3 H L-1cCH CH O O OCH.sub.3 CH.sub.3 H L-1dCH CH O O OCH.sub.3 CH.sub.3 H L-1eCH CH O O OCH.sub.3 CH.sub.3 H L-1fCH CH O O OCH.sub.3 CH.sub.3 H L-1gCH CH O O OCH.sub.3 CH.sub.3 H L-1hCH CH O O OCH.sub.3 CH.sub.3 H L-1iCH CH O O OCH.sub.3 CH.sub. 3 H L-1jCH CH O O OCH.sub.3 CH.sub.3 H L-1kCH CH O O OCH.sub.3 CH.sub.3 H L-3aCH CH O O OCH.sub.3 CH.sub.3 H L-3bCH CH O O OCH.sub.3 CH.sub.3 H L-4aCH CH O O OCH.sub.3 CH.sub.3 H L-7aCH CH O O OCH.sub.3 CH.sub.3 H L-8aCH CH O O OCH.sub.3 CH.sub.3 H L-8bCH CH O O OCH.sub.3 CH.sub.3 H L-9aCH CH O O OCH.sub.3 CH.sub.3 H L-12aCH CH O O OCH.sub.3 CH.sub.3 H L-12bCH CH O O OCH.sub.3 CH.sub.3 H L-14aCH CH O O OCH.sub.3 CH.sub.3 H L-15aCH CH O O OCH.sub.3 CH.sub.3 H L-16aCH CH O O OCH.sub.3 CH.sub.3 H L-16bCH CH O O OCH.sub.3 CH.sub.3 H L-18aCH CH O O OCH.sub.3 CH.sub.3 H L-20aCH CH O O OCH.sub.3 CH.sub.3 H L-22aCH CH O S OCH.sub.3 CH.sub.3 H L-1aCH CH O O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH O O CH.sub.3 OCH.sub.3 H L-1aCH CH O O CH.sub.3 OCH.sub.3 H L-1bCH CH O O CH.sub.3 OCH.sub.3 H L-1cCH CH O O CH.sub.3 OCH.sub.3 H L-1dCH CH O O CH.sub.3 OCH.sub.3 H L-1eCH CH O O CH.sub.3 OCH.sub.3 H L-1fCH CH O O CH.sub.3 OCH.sub.3 H L-1gCH CH O O CH.sub.3 OCH.sub.3 H L-1hCH CH O O CH.sub.3 OCH.sub.3 H L-1iCH CH O O CH.sub.3 OCH.sub.3 H L-1jCH CH O O CH.sub.3 OCH.sub.3 H L-1kCH CH O O CH.sub.3 OCH.sub.3 H L-3aCH CH O O CH.sub.3 OCH.sub.3 H L-3bCH CH O O CH.sub.3 OCH.sub.3 H L-4aCH CH O O CH.sub.3 OCH.sub.3 H L-7aCH CH O O CH.sub.3 OCH.sub.3 H L-8aCH CH O O CH.sub.3 OCH.sub.3 H L-8bCH CH O O CH.sub.3 OCH.sub.3 H L-9aCH CH O O CH.sub.3 OCH.sub.3 H L-12aCH CH O O CH.sub.3 OCH.sub.3 H L-12bCH CH O O CH.sub.3 OCH.sub.3 H L-14aCH CH O O CH.sub.3 OCH.sub.3 H L-15aCH CH O O CH.sub.3 OCH.sub.3 H L-16aCH CH O O CH.sub.3 OCH.sub.3 H L-16bCH CH O O CH.sub.3 OCH.sub.3 H L-18aCH CH O O CH.sub.3 OCH.sub.3 H L-20aCH CH O O CH.sub.3 OCH.sub.3 H L-22aCH CH O S CH.sub.3 OCH.sub.3 H L-1aCH CH O O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH O O OCH.sub.3 OCH.sub.3 H L-1aCH CH O O OCH.sub.3 OCH.sub.3 H L-1bCH CH O O OCH.sub.3 OCH.sub.3 H L-1cCH CH O O OCH.sub.3 OCH.sub.3 H L-1dCH CH O O OCH.sub.3 OCH.sub.3 H L-1eCH CH O O OCH.sub.3 OCH.sub.3 H L-1fCH CH O O OCH.sub.3 OCH.sub.3 H L-1gCH CH O O OCH.sub.3 OCH.sub.3 H L-1hCH CH O O OCH.sub.3 OCH.sub.3 H L-1iCH CH O O OCH.sub.3 OCH.sub.3 H L-1jCH CH O O OCH.sub.3 OCH.sub.3 H L-1kCH CH O O OCH.sub. 3 OCH.sub.3 H L-3aCH CH O O OCH.sub.3 OCH.sub.3 H L-3bCH CH O O OCH.sub.3 OCH.sub.3 H L-4aCH CH O O OCH.sub.3 OCH.sub.3 H L-7aCH CH O O OCH.sub.3 OCH.sub.3 H L-8aCH CH O O OCH.sub.3 OCH.sub.3 H L-8bCH CH O O OCH.sub.3 OCH.sub.3 H L-9aCH CH O O OCH.sub.3 OCH.sub.3 H L-12aCH CH O O OCH.sub.3 OCH.sub.3 H L-12bCH CH O O OCH.sub.3 OCH.sub.3 H L-14aCH CH O O OCH.sub.3 OCH.sub.3 H L-15aCH CH O O OCH.sub.3 OCH.sub.3 H L-16aCH CH O O OCH.sub.3 OCH.sub.3 H L-16bCH CH O O OCH.sub.3 OCH.sub.3 H L-18aCH CH O O OCH.sub.3 OCH.sub.3 H L-20aCH CH O O OCH.sub.3 OCH.sub.3 H L-22aCH CH O S OCH.sub.3 OCH.sub.3 H L-1aCH CH O O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH S O CH.sub.3 CH.sub.3 H L-1aN CH S O CH.sub.3 CH.sub.3 H L-1bH CH S O CH.sub.3 CH.sub.3 H L-1cN CH S O CH.sub.3 CH.sub.3 H L-1dN CH S O CH.sub.3 CH.sub.3 H L-1fN CH S O CH.sub.3 CH.sub.3 H L-1fN CH S O CH.sub.3 CH.sub.3 H L-1gN CH S O CH.sub.3 CH.sub.3 H L-1hN CH S O CH.sub.3 CH.sub.3 H L-1iN CH S O CH.sub.3 CH.sub.3 H L-1jN CH S O CH.sub.3 CH.sub.3 H L-1kN CH S O CH.sub.3 CH.sub.3 H L-3aN CH S O CH.sub.3 CH.sub.3 H L-3bN CH S O CH.sub.3 CH.sub.3 H L-4aN CH S O CH.sub.3 CH.sub.3 H L-7aN CH S O CH.sub.3 CH.sub.3 H L-8aN CH S O CH.sub.3 CH.sub.3 H L-8bN CH S O CH.sub.3 CH.sub.3 H L-9aN CH S O CH.sub.3 CH.sub.3 H L-12aN CH S O CH.sub.3 CH.sub.3 H L-12bN CH S O CH.sub.3 CH.sub.3 H L-14aN CH S O CH.sub.3 CH.sub.3 H L-15aN CH S O CH.sub.3 CH.sub.3 H L-16aN CH S O CH.sub.3 CH.sub.3 H L-16bN CH S O CH.sub.3 CH.sub.3 H L-18aN CH S O CH.sub.3 CH.sub.3 H L-20aN CH S O CH.sub.3 CH.sub.3 H L-22aN CH S S CH.sub.3 CH.sub.3 H L-1aN CH S O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH S O OCH.sub.3 CH.sub.3 H L-1aN CH S O OCH.sub.3 CH.sub.3 H L-1bN CH S O OCH.sub.3 CH.sub.3 H L-1cN CH S O OCH.sub.3 CH.sub.3 H L-1dN CH S O OCH.sub.3 CH.sub.3 H L-1eN CH S O OCH.sub.3 CH.sub.3 H L-1fN CH S O OCH.sub.3 CH.sub.3 H L-1gN CH S O OCH.sub.3 CH.sub.3 H L-1hN CH S O OCH.sub.3 CH.sub.3 H L-1iN CH S O OCH.sub.3 CH.sub.3 H L-1jN CH S O OCH.sub.3 CH.sub.3 H L-1kN CH S O OCH.sub.3 CH.sub.3 H L-3aN CH S O OCH.sub.3 CH.sub.3 H L-3bN CH S O OCH.sub.3 CH.sub.3 H L-4aN CH S O OCH.sub.3 CH.sub.3 H L-7aN CH S O OCH.sub.3 CH.sub.3 H L-8aN CH S O OCH.sub.3 CH.sub.3 H L-8bN CH S O OCH.sub.3 CH.sub.3 H L-9aN CH S O OCH.sub.3 CH.sub.3 H L-12aN CH S O OCH.sub.3 CH.sub.3 H L-12bN CH S O OCH.sub.3 CH.sub.3 H L-14aN CH S O OCH.sub.3 CH.sub.3 H L-15aN CH S O OCH.sub.3 CH.sub.3 H L-16aN CH S O OCH.sub.3 CH.sub.3 H L-16bN CH S O OCH.sub.3 CH.sub.3 H L-18aN CH S O OCH.sub.3 CH.sub.3 H L-20aN CH S O OCH.sub.3 CH.sub.3 H L-22aN CH S S OCH.sub.3 CH.sub.3 H L-1aN CH S O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH S O CH.sub.3 OCH.sub.3 H L-1aN CH S O CH.sub.3 OCH.sub.3 H L-1bN CH S O CH.sub.3 OCH.sub.3 H L-1cN CH S O CH.sub.3 OCH.sub.3 H L-1dN CH S O CH.sub.3 OCH.sub.3 H L-1eN CH S O CH.sub.3 OCH.sub.3 H L-1fN CH S O CH.sub.3 OCH.sub.3 H L-1gN CH S O CH.sub.3 OCH.sub.3 H L-1hN CH S O CH.sub.3 OCH.sub.3 H L-1iN CH S O CH.sub.3 OCH.sub.3 H L-1jN CH S O CH.sub.3 OCH.sub.3 H L-1kN CH S O CH.sub.3 OCH.sub.3 H L-3aN CH S O CH.sub.3 OCH.sub.3 H L-3bN CH S O CH.sub.3 OCH.sub.3 H L-4aN CH S O CH.sub.3 OCH.sub.3 H L-7aN CH S O CH.sub.3 OCH.sub.3 H L-8aN CH S O CH.sub.3 OCH.sub.3 H L-8bN CH S O CH.sub.3 OCH.sub.3 H L-9aN CH S O CH.sub.3 OCH.sub.3 H L-12aN CH S O CH.sub.3 OCH.sub.3 H L-12bN CH S O CH.sub.3 OCH.sub.3 H L-14aN CH S O CH.sub.3 OCH.sub.3 H L-15aN CH S O CH.sub.3 OCH.sub.3 H L-16aN CH S O CH.sub.3 OCH.sub.3 H L-16bN CH S O CH.sub.3 OCH.sub.3 H L-18aN CH S O CH.sub.3 OCH.sub.3 H L-20aN CH S O CH.sub.3 OCH.sub.3 H L-22aN CH S O CH.sub.3 OCH.sub.3 H L-1aN CH S O CH.sub.3 OCH.sub.3 CH L-1aN CH S O OCH.sub.3 OCH.sub.3 H L-1aN CH S O OCH.sub.3 OCH.sub.3 H L-1bN CH S O OCH.sub.3 OCH.sub.3 H L-1cN CH S O OCH.sub.3 OCH.sub.3 H L-1dN CH S O OCH.sub.3 OCH.sub.3 H L-1eN CH S O OCH.sub.3 OCH.sub.3 H L-1eN CH S O OCH.sub.3 OCH.sub.3 H L-1fN CH S O OCH.sub.3 OCH.sub.3 H L-1gN CH S O OCH.sub.3 OCH.sub.3 H L-1hN CH S O OCH.sub.3 OCH.sub.3 H L-1iN CH S O OCH.sub.3 OCH.sub.3 H L-1jN CH S O OCH.sub.3 OCH.sub.3 H L-1kN CH S O OCH.sub.3 OCH.sub.3 H L-3aN CH S O OCH.sub.3 OCH.sub.3 H L-3bN CH S O OCH.sub.3 OCH.sub.3 H L-4aN CH S O OCH.sub.3 OCH.sub.3 H L-7aN CH S O OCH.sub.3 OCH.sub.3 H L-8aN CH S O OCH.sub.3 OCH.sub.3 H L-8bN CH S O OCH.sub.3 OCH.sub.3 H L-9aN CH S O OCH.sub.3 OCH.sub.3 H L-12aN CH S O OCH.sub.3 OCH.sub.3 H L-12bN CH S O OCH.sub.3 OCH.sub.3 H L-14aN CH S O OCH.sub.3 OCH.sub.3 H L-15aN CH S O OCH.sub.3 OCH.sub.3 H L-16aN CH S O OCH.sub.3 OCH.sub.3 H L-16bN CH S O OCH.sub.3 OCH.sub.3 H L-18aN CH S O OCH.sub.3 OCH.sub.3 H L-20aN CH S O OCH.sub.3 OCH.sub.3 H L-22aN CH S O OCH.sub.3 OCH.sub.3 H L-1aN CH S O OCH.sub.3 OCH.sub.3 H L-1aN CH O O CH.sub.3 CH.sub.3 H L-1aN CH O O CH.sub.3 CH.sub.3 H L-1bN CH O O CH.sub.3 CH.sub.3 H L-1cN CH O O CH.sub.3 CH.sub.3 H L-1dN CH O O CH.sub.3 CH.sub.3 H L-1eN CH O O CH.sub.3 CH.sub.3 H L-1fN CH O O CH.sub.3 CH.sub.3 H L-1gN CH O O CH.sub.3 CH.sub.3 H L-1hN CH O O CH.sub.3 CH.sub.3 H L-1iN CH O O CH.sub.3 CH.sub.3 H L-1jN CH O O CH.sub.3 CH.sub.3 H L-1kN CH O O CH.sub.3 CH.sub.3 H L-3aN CH O O CH.sub.3 CH.sub.3 H L-3bN CH O O CH.sub.3 CH.sub.3 H L-4aN CH O O CH.sub.3 CH.sub.3 H L-7aN CH O O CH.sub.3 CH.sub.3 H L-8aN CH O O CH.sub.3 CH.sub.3 H L-8bN CH O O CH.sub.3 CH.sub.3 H L-9aN CH O O CH.sub.3 CH.sub.3 H L-12aN CH O O CH.sub.3 CH.sub.3 H L-12bN CH O O CH.sub.3 CH.sub.3 H L-14aN CH O O CH.sub.3 CH.sub.3 H L-15aN CH O O CH.sub.3 CH.sub.3 H L-16aN CH O O CH.sub.3 CH.sub.3 H L-16bN CH O O CH.sub.3 CH.sub.3 H L-18aN CH O O CH.sub.3 CH.sub.3 H L-20aN CH O O CH.sub.3 CH.sub.3 H L-22aN CH O S CH.sub.3 CH.sub.3 H L-1aN CH O O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH O O OCH.sub.3 CH.sub.3 H L-1aN CH O O OCH.sub.3 CH.sub.3 H L-1bN CH O O OCH.sub.3 CH.sub.3 H L-1cN CH O O OCH.sub.3 CH.sub.3 H L-1dN CH O O OCH.sub.3 CH.sub.3 H L-1eN CH O O OCH.sub.3 CH.sub.3 H L-1fN CH O O OCH.sub.3 CH.sub.3 H L-1gN CH O O OCH.sub.3 CH.sub.3 H L-1hN CH O O OCH.sub.3 CH.sub.3 H L-1iN CH O O OCH.sub.3 CH.sub.3 H L-1jN CH O O OCH.sub.3 CH.sub.3 H L-1kN CH O O OCH.sub.3 CH.sub.3 H L-3aN CH O O OCH.sub.3 CH.sub.3 H L-3bN CH O O OCH.sub.3 CH.sub.3 H L-4aN CH O O OCH.sub.3 CH.sub.3 H L-7aN CH O O OCH.sub.3 CH.sub.3 H L-8aN CH O O OCH.sub.3 CH.sub.3 H L-8bN CH O O OCH.sub.3 CH.sub.3 H L-9aN CH O O OCH.sub.3 CH.sub.3 H L-12aN CH O O OCH.sub.3 CH.sub.3 H L-12bN CH O O OCH.sub.3 CH.sub.3 H L-14aN CH O O OCH.sub.3 CH.sub.3 H L-15aN CH O O OCH.sub.3 CH.sub.3 H L-16aN CH O O OCH.sub.3 CH.sub.3 H L-16bN CH O O CH.sub.3 CH.sub.3 H L-18aN CH O O OCH.sub.3 CH.sub.3 H L-20aN CH O O OCH.sub.3 CH.sub.3 H L-22aN CH O S OCH.sub.3 CH.sub.3 H L-1aN CH O O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH O O CH.sub.3 OCH.sub.3 H L-1aN CH O O CH.sub.3 OCH.sub.3 H L-1bN CH O O CH.sub.3 OCH.sub.3 H L-1cN CH O O CH.sub.3 OCH.sub.3 H L-1dN CH O O CH.sub.3 OCH.sub.3 H L-1eN CH O O CH.sub.3 OCH.sub.3 H L-1fN CH O O CH.sub.3 OCH.sub.3 H L-1gN CH O O CH.sub.3 OCH.sub.3 H L-1hN CH O O CH.sub.3 OCH.sub.3 H L-1iN CH O O CH.sub.3 OCH.sub.3 H L-1jN CH O O CH.sub.3 OCH.sub.3 H L-1kN CH O O CH.sub.3 OCH.sub.3 H L-3aN CH O O CH.sub.3 OCH.sub.3 H L-3bN CH O O CH.sub.3 OCH.sub.3 H L-4aN CH O O CH.sub.3 OCH.sub.3 H L-7aN CH O O CH.sub.3 OCH.sub.3 H L-8aN CH O O CH.sub.3 OCH.sub.3 H L-8bN CH O O CH.sub.3 OCH.sub.3 H L-9aN CH O O CH.sub.3 OCH.sub.3 H L-12aN CH O O CH.sub.3 OCH.sub.3 H L-12bN CH O O CH.sub.3 OCH.sub.3 H L-14aN CH O O CH.sub.3 OCH.sub.3 H L-15aN CH O O CH.sub.3 OCH.sub.3 H L-16aN CH O O CH.sub.3 OCH.sub.3 H L-16bN CH O O CH.sub.3 OCH.sub.3 H L-18aN CH O O CH.sub.3 OCH.sub.3 H L-20aN CH O O CH.sub.3 OCH.sub.3 H L-22aN CH O S CH.sub.3 OCH.sub.3 H L-1aN CH O O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH O O OCH.sub.3 OCH.sub.3 H L-1aN CH O O OCH.sub.3 OCH.sub.3 H L-1bN CH O O OCH.sub.3 OCH.sub.3 H L-1cN CH O O OCH.sub.3 OCH.sub.3 H L-1dN CH O O OCH.sub.3 OCH.sub.3 H L-1eN CH O O OCH.sub.3 OCH.sub.3 H L-1fN CH O O OCH.sub.3 OCH.sub.3 H L-1gN CH O O OCH.sub.3 OCH.sub.3 H L-1hN CH O O OCH.sub.3 OCH.sub.3 H L-1iN CH O O OCH.sub.3 OCH.sub.3 H L-1jN CH O O OCH.sub.3 OCH.sub.3 H L-1kN CH O O OCH.sub.3 OCH.sub.3 H L-3aN CH O O OCH.sub.3 OCH.sub.3 H L-3bN CH O O OCH.sub.3 OCH.sub.3 H L-4aN CH O O OCH.sub.3 OCH.sub.3 H L-7aN CH O O OCH.sub.3 OCH.sub.3 H L-8aN CH O O OCH.sub.3 OCH.sub.3 H L-8bN CH O O OCH.sub.3 OCH.sub.3 H L-9aN CH O O OCH.sub.3 OCH.sub.3 H L-12aN CH O O OCH.sub.3 OCH.sub.3 H L-12bN CH O O OCH.sub.3 OCH.sub.3 H L-14aN CH O O OCH.sub.3 OCH.sub.3 H L-15aN CH O O OCH.sub.3 OCH.sub.3 H L-16aN CH O O OCH.sub.3 OCH.sub.3 H L-16bN CH O O OCH.sub.3 OCH.sub.3 H L-18aN CH O O OCH.sub.3 OCH.sub.3 H L-20aN CH O O OCH.sub.3 OCH.sub.3 H L-22aN CH O O OCH.sub.3 OCH.sub.3 H L-1aN CH O O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1cCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1dCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1dCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1eCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1fCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1gCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1hCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1iCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1jCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1kCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-3aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-3bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-4aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-7aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-8aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-8bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-9aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-12aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-12bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-14aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-15aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-16aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-16bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-18aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-20aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-22aCH CH NCH.sub.3 S CH.sub.3 CH.sub.3 H L-1aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1cCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1dCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1eCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1fCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1gCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1hCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1iCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1jCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1kCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-3aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-3bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-4aCH CH NCH.sub. 3 O OCH.sub.3 CH.sub.3 H L-7aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-8aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-8bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-9aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-12aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-12bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-14aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-15aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-16aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-16aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-18aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-20aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-22aCH CH NCH.sub.3 S OCH.sub.3 CH.sub.3 H L-1aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1cCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1dCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1eCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1fCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1gCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1hCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1iCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1jCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1kCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-3aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-3bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-4aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-7aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-8aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-8bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-9aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-12aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-12bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-14aCH CH NCH.sub.3 O CH.sub. 3 OCH.sub.3 H L-15aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-16aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-16bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-18aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-20aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-22aCH CH NCH.sub.3 S CH.sub.3 OCH.sub.3 H L-1aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1cCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1dCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1eCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1fCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1gCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1hCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1iCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1jCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1kCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-3aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-3bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-4aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-7aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-8aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-8bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-9aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-12aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-12bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-14aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-15aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-16aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-16bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-18aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-20aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-22aCH CH NCH.sub.3 S OCH.sub.3 OCH.sub.3 H L-1aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1bCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1cCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1dCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1eCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1fCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1gCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1hCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1iCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1jCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1kCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-3aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-3bCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-4aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-7aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-8aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-8bCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-9aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-12aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-12bCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-14aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-15aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-16aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-16bCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-18aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-20aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-22aCH CH CH.sub.2 S CH.sub.3 CH.sub.3 H L-1aCH CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1bCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1cCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1dCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1eCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1fCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1gCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1hCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1iCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1jCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1kCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-3aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-3bCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-4aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-7aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-8aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-8bCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-8aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-9aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-12aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-12bCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-14aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-15aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-16aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-16bCH CH CH.sub. 2 O OCH.sub.3 CH.sub.3 H L-18aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-20aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-22aCH CH CH.sub.2 S OCH.sub.3 CH.sub.3 H L-1aCH CH CH.sub.2 O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1bCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1cCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1dCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1eCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1fCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1gCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1hCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1iCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1jCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1kCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-3aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-3bCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-4aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-7aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-8aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-8bCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-9aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-12aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-12bCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-14aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-15aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-16aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-16bCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-18aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-20aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-22aCH CH CH.sub.2 S CH.sub.3 OCH.sub.3 H L-1aCH CH CH.sub.2 O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1bCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1cCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1dCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1eCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1fCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1gCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1hCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1iCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1jCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1kCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-3aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-3bCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-4aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-7aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-8aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-8bCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-9aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-12aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-12bCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-14aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-15aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-16aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-16bCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-18aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-20aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-22aCH CH CH.sub.2 S OCH.sub.3 OCH.sub.3 H L-1aCH CH CH.sub.2 O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1cN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1dN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1eN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1fN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1gN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1hN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1iN CH NCH.sub.3 O CH.sub.3 CH.sub. 3 H L-1jN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1kN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-3aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-3bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-4aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-7aN CH NCH O CH.sub.3 CH.sub.3 H L-8aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-8bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-9aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-12aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-12bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-14aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-15aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-16aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-16bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-18aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-20aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-22aN CH NCH.sub.3 S CH.sub.3 CH.sub.3 H L-1aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1cN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1dN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1eN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1fN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1gN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1hN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1iN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1jN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1kN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-3aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-3bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-4aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-7aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-8aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-8bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-9aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-12aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-12bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-14aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-15aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-16aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-16bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-18aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-20aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-22aN CH NCH.sub.3 S OCH.sub.3 CH.sub.3 H L-1aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1cN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1dN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1eN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1fN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1gN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1hN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1iN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1jN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1kN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-3aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-3bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-4aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-7aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-8aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-8bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-9aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-12aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-12bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-14aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-15aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-16aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-16bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-18aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-20aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-22aN CH NCH.sub.3 S CH.sub.3 OCH.sub.3 H L-1aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1cN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1dN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1eN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1fN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1gN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1hN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1iN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1jN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1kN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-3aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-3bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-4aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-7aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-8aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-8bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-9aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-12aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-12bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-14aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-15aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-16aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-16bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-18aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-20aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-22aN CH NCH.sub.3 S OCH.sub.3 OCH.sub.3 H L-1aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1bN CH CH.sub.2 O CH.sub. 3 CH.sub.3 H L-1cN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1dN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1eN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1fN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1gN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1hN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1iN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1jN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-1kN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-3aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-3bN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-4aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-7aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-8aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-8bN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-9aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-12aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-12bN CH CH.sub.2 O CH.sub.3 CH.sub. 3 H L-14aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-15aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-16aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-16bN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-18aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-20aN CH CH.sub.2 O CH.sub.3 CH.sub.3 H L-22aN CH CH.sub.2 S CH.sub.3 CH.sub.3 H L-1aN CH CH.sub.2 O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1bN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1cN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1dN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1eN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1fN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1gN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1hN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1iN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1jN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-1kN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-3aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-3bN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-4aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-7aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-8aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-8bN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-9aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-12aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-12bN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-14aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-15aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-16aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-16bN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-18aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-20aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 H L-22aN CH CH.sub.2 S OCH.sub.3 CH.sub.3 H L-1aN CH CH.sub.2 O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1bN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1cN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1dN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1eN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1fN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1gN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1hN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1iN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1jN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-1kN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-3aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-3bN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-4aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-7aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-8aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-8bN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-9aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-12aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-12bN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-14aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-15aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-16aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-16bN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-18aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-20aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 H L-22aN CH CH.sub.2 S CH.sub.3 OCH.sub.3 H L-1aN CH CH.sub.2 O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1bN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1cN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1dN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1eN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1fN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1gN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1hN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1iN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1jN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-1kN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-3aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-3bN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-4aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-7aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-8aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-8bN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-9aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-12aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-12bN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-14aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-15aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-16aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-16bN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-18aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-20aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 H L-22aN CH CH.sub.2 S OCH.sub.3 OCH.sub.3 H L-1aN CH CH.sub.2 O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1a______________________________________
TABLE 5__________________________________________________________________________General Formula 5Z Z.sub.1 Z.sub.2 Z.sub.3 W X Y R L m.p. (.degree.C.)__________________________________________________________________________CH N CH CH O CH.sub.3 CH.sub.3 H L-1aCH N CH CH O CH.sub.3 CH.sub.3 H L-1bCH N CH CH O CH.sub.3 CH.sub.3 H L-1cCH N CH CH O CH.sub.3 CH.sub.3 H L-1dCH N CH CH O CH.sub.3 CH.sub.3 H L-1eCH N CH CH O CH.sub.3 CH.sub.3 H L-1fCH N CH CH O CH.sub.3 CH.sub.3 H L-1gCH N CH CH O CH.sub.3 CH.sub.3 H L-1hCH N CH CH O CH.sub.3 CH.sub.3 H L-1iCH N CH CH O CH.sub.3 CH.sub.3 H L-1jCH N CH CH O CH.sub.3 CH.sub.3 H L-1kCH N CH CH O CH.sub.3 CH.sub.3 H L-3aCH N CH CH O CH.sub.3 CH.sub.3 H L-3bCH N CH CH O CH.sub.3 CH.sub.3 H L-4aCH N CH CH O CH.sub.3 CH.sub.3 H L-7aCH N CH CH O CH.sub.3 CH.sub.3 H L-8aCH N CH CH O CH.sub.3 CH.sub.3 H L-8bCH N CH CH O CH.sub.3 CH.sub.3 H L-9aCH N CH CH O CH.sub.3 CH.sub.3 H L-12aCH N CH CH O CH.sub.3 CH.sub.3 H L-12bCH N CH CH O CH.sub.3 CH.sub.3 H L-14aCH N CH CH O CH.sub.3 CH.sub.3 H L-15aCH N CH CH O CH.sub.3 CH.sub.3 H L-16aCH N CH CH O CH.sub.3 CH.sub.3 H L-16bCH N CH CH O CH.sub.3 CH.sub.3 H L-18aCH N CH CH O CH.sub.3 CH.sub.3 H L-20aCH N CH CH O CH.sub.3 CH.sub.3 H L-22aCH N CH CH S CH.sub.3 CH.sub.3 H L-1aCH N CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH CH O OCH.sub.3 CH.sub.3 H L-1aCH N CH CH O OCH.sub.3 CH.sub.3 H L-1bCH N CH CH O OCH.sub.3 CH.sub.3 H L-1cCH N CH CH O OCH.sub.3 CH.sub.3 H L-1dCH N CH CH O OCH.sub.3 CH.sub.3 H L-1eCH N CH CH O OCH.sub.3 CH.sub.3 H L-1fCH N CH CH O OCH.sub.3 CH.sub.3 H L-1gCH N CH CH O OCH.sub.3 CH.sub.3 H L-1hCH N CH CH O OCH.sub.3 CH.sub.3 H L-1iCH N CH CH O OCH.sub.3 CH.sub.3 H L-1jCH N CH CH O OCH.sub.3 CH.sub.3 H L-1kCH N CH CH O OCH.sub.3 CH.sub.3 H L-3aCH N CH CH O OCH.sub.3 CH.sub.3 H L-3bCH N CH CH O OCH.sub.3 CH.sub.3 H L-4aCH N CH CH O OCH.sub.3 CH.sub.3 H L-7aCH N CH CH O OCH.sub.3 CH.sub.3 H L-8aCH N CH CH O OCH.sub.3 CH.sub.3 H L-8bCH N CH CH O OCH.sub.3 CH.sub.3 H L-9aCH N CH CH O OCH.sub.3 CH.sub.3 H L-12aCH N CH CH O OCH.sub.3 CH.sub.3 H L-12bCH N CH CH O OCH.sub.3 CH.sub.3 H L-14aCH N CH CH O OCH.sub.3 CH.sub.3 H L-15aCH N CH CH O OCH.sub.3 CH.sub.3 H L-16aCH N CH CH O OCH.sub.3 CH.sub.3 H L-16bCH N CH CH O OCH.sub.3 CH.sub.3 H L-18aCH N CH CH O OCH.sub.3 CH.sub.3 H L-20aCH N CH CH O OCH.sub.3 CH.sub.3 H L-22aCH N CH CH S OCH.sub.3 CH.sub.3 H L-1aCH N CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH CH O CH.sub.3 OCH.sub.3 H L-1aCH N CH CH O CH.sub.3 OCH.sub.3 H L-1bCH N CH CH O CH.sub.3 OCH.sub.3 H L-1cCH N CH CH O CH.sub.3 OCH.sub.3 H L-1dCH N CH CH O CH.sub.3 OCH.sub.3 H L-1eCH N CH CH O CH.sub.3 OCH.sub.3 H L-1fCH N CH CH O CH.sub.3 OCH.sub.3 H L-1gCH N CH CH O CH.sub.3 OCH.sub.3 H L-1hCH N CH CH O CH.sub.3 OCH.sub.3 H L-1iCH N CH CH O CH.sub.3 OCH.sub.3 H L-1jCH N CH CH O CH.sub.3 OCH.sub.3 H L-1kCH N CH CH O CH.sub.3 OCH.sub.3 H L-3aCH N CH CH O CH.sub.3 OCH.sub.3 H L-3bCH N CH CH O CH.sub.3 OCH.sub.3 H L-4aCH N CH CH O CH.sub.3 OCH.sub.3 H L-7aCH N CH CH O CH.sub.3 OCH.sub.3 H L-8aCH N CH CH O CH.sub.3 OCH.sub.3 H L-8bCH N CH CH O CH.sub.3 OCH.sub.3 H L-9aCH N CH CH O CH.sub.3 OCH.sub.3 H L-12aCH N CH CH O CH.sub.3 OCH.sub.3 H L-12bCH N CH CH O CH.sub.3 OCH.sub.3 H L-14aCH N CH CH O CH.sub.3 OCH.sub.3 H L-15aCH N CH CH O CH.sub.3 OCH.sub.3 H L-16aCH N CH CH O CH.sub.3 OCH.sub.3 H L-16bCH N CH CH O CH.sub.3 OCH.sub.3 H L-18aCH N CH CH O CH.sub.3 OCH.sub.3 H L-20aCH N CH CH O CH.sub.3 OCH.sub.3 H L-22aCH N CH CH S CH.sub.3 OCH.sub.3 H L-1aCH N CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1bCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1cCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1dCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1eCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1fCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1gCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1hCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1iCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1jCH N CH CH O OCH.sub.3 OCH.sub.3 H L-1kCH N CH CH O OCH.sub.3 OCH.sub.3 H L-3aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-3bCH N CH CH O OCH.sub.3 OCH.sub.3 H L-4aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-7aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-8aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-8bCH N CH CH O OCH.sub.3 OCH.sub. 3 H L-9aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-12aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-12bCH N CH CH O OCH.sub.3 OCH.sub.3 H L-14aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-15aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-16aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-16bCH N CH CH O OCH.sub.3 OCH.sub.3 H L-18aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-20aCH N CH CH O OCH.sub.3 OCH.sub.3 H L-22aCH N CH CH S OCH.sub.3 OCH.sub.3 H L-1aCH N CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N N CH O CH.sub.3 CH.sub.3 H L-1aCH N N CH O CH.sub.3 CH.sub.3 H L-1bCH N N CH O CH.sub.3 CH.sub.3 H L-1cCH N N CH O CH.sub.3 CH.sub.3 H L-1dCH N N CH O CH.sub.3 CH.sub.3 H L-1eCH N N CH O CH.sub.3 CH.sub.3 H L-1fCH N N CH O CH.sub.3 CH.sub.3 H L-1gCH N N CH O CH.sub.3 CH.sub.3 H L-1hCH N N CH O CH.sub.3 CH.sub.3 H L-1iCH N N CH O CH.sub.3 CH.sub.3 H L-1jCH N N CH O CH.sub.3 CH.sub.3 H L-1kCH N N CH O CH.sub.3 CH.sub.3 H L-3aCH N N CH O CH.sub.3 CH.sub.3 H L-3bCH N N CH O CH.sub.3 CH.sub.3 H L-4aCH N N CH O CH.sub.3 CH.sub.3 H L-7aCH N N CH O CH.sub.3 CH.sub.3 H L-8aCH N N CH O CH.sub.3 CH.sub.3 H L-8bCH N N CH O CH.sub.3 CH.sub.3 H L-9aCH N N CH O CH.sub.3 CH.sub.3 H L-12aCH N N CH O CH.sub.3 CH.sub.3 H L-12bCH N N CH O CH.sub.3 CH.sub.3 H L-14aCH N N CH O CH.sub.3 CH.sub.3 H L-15aCH N N CH O CH.sub.3 CH.sub.3 H L-16aCH N N CH O CH.sub.3 CH.sub.3 H L-16bCH N N CH O CH.sub.3 CH.sub.3 H L-18aCH N N CH O CH.sub.3 CH.sub.3 H L-20aCH N N CH O CH.sub.3 CH.sub.3 H L-22aCH N N CH S CH.sub.3 CH.sub.3 H L-1aCH N N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N N CH O OCH.sub.3 CH.sub.3 H L-1aCH N N CH O OCH.sub.3 CH.sub.3 H L-1bCH N N CH O OCH.sub.3 CH.sub.3 H L-1cCH N N CH O OCH.sub.3 CH.sub.3 H L-1dCH N N CH O OCH.sub.3 CH.sub.3 H L-1eCH N N CH O OCH.sub.3 CH.sub.3 H L-1fCH N N CH O OCH.sub.3 CH.sub.3 H L-1gCH N N CH O OCH.sub.3 CH.sub.3 H L-1hCH N N CH O OCH.sub.3 CH.sub.3 H L-1iCH N N CH O OCH.sub.3 CH.sub.3 H L-1jCH N N CH O OCH.sub.3 CH.sub.3 H L-1kCH N N CH O OCH.sub.3 CH.sub.3 H L-3aCH N N CH O OCH.sub.3 CH.sub.3 H L-3bCH N N CH O OCH.sub.3 CH.sub.3 H L-4aCH N N CH O OCH.sub.3 CH.sub.3 H L-7aCH N N CH O OCH.sub.3 CH.sub.3 H L-8aCH N N CH O OCH.sub.3 CH.sub.3 H L-8bCH N N CH O OCH.sub.3 CH.sub.3 H L-9aCH N N CH O OCH.sub.3 CH.sub.3 H L-12aCH N N CH O OCH.sub.3 CH.sub.3 H L-12bCH N N CH O OCH.sub.3 CH.sub.3 H L-14aCH N N CH O OCH.sub.3 CH.sub.3 H L-15aCH N N CH O OCH.sub.3 CH.sub.3 H L-16aCH N N CH O OCH.sub.3 CH.sub.3 H L-16bCH N N CH O OCH.sub.3 CH.sub.3 H L-18aCH N N CH O OCH.sub.3 CH.sub.3 H L-20aCH N N CH O OCH.sub.3 CH.sub.3 H L-22aCH N N CH S OCH.sub.3 CH.sub.3 H L-1aCH N N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N N CH O CH.sub.3 OCH.sub.3 H L-1aCH N N CH O CH.sub.3 OCH.sub.3 H L-1bCH N N CH O CH.sub.3 OCH.sub.3 H L-1cCH N N CH O CH.sub.3 OCH.sub.3 H L-1dCH N N CH O CH.sub.3 OCH.sub.3 H L-1eCH N N CH O CH.sub.3 OCH.sub.3 H L-1fCH N N CH O CH.sub.3 OCH.sub.3 H L-1gCH N N CH O CH.sub.3 OCH.sub.3 H L-1hCH N N CH O CH.sub.3 OCH.sub.3 H L-1iCH N N CH O CH.sub.3 OCH.sub.3 H L-1jCH N N CH O CH.sub.3 OCH.sub.3 H L-1kCH N N CH O CH.sub.3 OCH.sub.3 H L-3aCH N N CH O CH.sub.3 OCH.sub.3 H L-3bCH N N CH O CH.sub.3 OCH.sub.3 H L-4aCH N N CH O CH.sub.3 OCH.sub.3 H L-7aCH N N CH O CH.sub.3 OCH.sub.3 H L-8aCH N N CH O CH.sub.3 OCH.sub.3 H L-8bCH N N CH O CH.sub.3 OCH.sub.3 H L-9aCH N N CH O CH.sub.3 OCH.sub.3 H L-12aCH N N CH O CH.sub.3 OCH.sub.3 H L-12bCH N N CH O CH.sub.3 OCH.sub.3 H L-14aCH N N CH O CH.sub.3 OCH.sub.3 H L-15aCH N N CH O CH.sub.3 OCH.sub.3 H L-16aCH N N CH O CH.sub.3 OCH.sub.3 H L-16bCH N N CH O CH.sub.3 OCH.sub.3 H L-18aCH N N CH O CH.sub.3 OCH.sub.3 H L-20aCH N N CH O CH.sub.3 OCH.sub.3 H L-22aCH N N CH S CH.sub.3 OCH.sub.3 H L-1aCH N N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N N CH O OCH.sub.3 OCH.sub.3 H L-1aCH N N CH O OCH.sub.3 OCH.sub.3 H L-1bCH N N CH O OCH.sub.3 OCH.sub.3 H L-1cCH N N CH O OCH.sub.3 OCH.sub.3 H L-1dCH N N CH O OCH.sub.3 OCH.sub.3 H L-1eCH N N CH O OCH.sub.3 OCH.sub.3 H L-1fCH N N CH O OCH.sub.3 OCH.sub.3 H L-1gCH N N CH O OCH.sub.3 OCH.sub.3 H L-1hCH N N CH O OCH.sub.3 OCH.sub.3 H L-1iCH N N CH O OCH.sub.3 OCH.sub.3 H L-1jCH N N CH O OCH.sub.3 OCH.sub.3 H L-1kCH N N CH O OCH.sub.3 OCH.sub.3 H L-3aCH N N CH O OCH.sub.3 OCH.sub.3 H L-3bCH N N CH O OCH.sub.3 OCH.sub.3 H L-4aCH N N CH O OCH.sub.3 OCH.sub.3 H L-7aCH N N CH O OCH.sub.3 OCH.sub.3 H L-8aCH N N CH O OCH.sub.3 OCH.sub.3 H L-8bCH N N CH O OCH.sub.3 OCH.sub.3 H L-9aCH N N CH O OCH.sub.3 OCH.sub.3 H L-12aCH N N CH O OCH.sub.3 OCH.sub.3 H L-12bCH N N CH O OCH.sub.3 OCH.sub.3 H L-14aCH N N CH O OCH.sub.3 OCH.sub.3 H L-15aCH N N CH O OCH.sub.3 OCH.sub.3 H L-16aCH N N CH O OCH.sub.3 OCH.sub.3 H L-16bCH N N CH O OCH.sub.3 OCH.sub.3 H L-18aCH N N CH O OCH.sub.3 OCH.sub.3 H L-20aCH N N CH O OCH.sub.3 OCH.sub.3 H L-22aCH N N CH S OCH.sub.3 OCH.sub.3 H L-1aCH N N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N CH O CH.sub.3 CH.sub.3 H L-1aCH CH N CH O CH.sub.3 CH.sub.3 H L-1bCH CH N CH O CH.sub.3 CH.sub.3 H L-1cCH CH N CH O CH.sub.3 CH.sub.3 H L-1dCH CH N CH O CH.sub.3 CH.sub.3 H L-1eCH CH N CH O CH.sub.3 CH.sub.3 H L-1fCH CH N CH O CH.sub.3 CH.sub.3 H L-1gCH CH N CH O CH.sub.3 CH.sub.3 H L-1hCH CH N CH O CH.sub.3 CH.sub.3 H L-1iCH CH N CH O CH.sub.3 CH.sub.3 H L-1jCH CH N CH O CH.sub.3 CH.sub.3 H L-1kCH CH N CH O CH.sub.3 CH.sub.3 H L-3aCH CH N CH O CH.sub.3 CH.sub.3 H L-3bCH CH N CH O CH.sub.3 CH.sub.3 H L-4aCH CH N CH O CH.sub.3 CH.sub.3 H L-7aCH CH N CH O CH.sub.3 CH.sub.3 H L-8aCH CH N CH O CH.sub.3 CH.sub.3 H L-8bCH CH N CH O CH.sub.3 CH.sub. 3 H L-9aCH CH N CH O CH.sub.3 CH.sub.3 H L-12aCH CH N CH O CH.sub.3 CH.sub.3 H L-12bCH CH N CH O CH.sub.3 CH.sub.3 H L-14aCH CH N CH O CH.sub.3 CH.sub.3 H L-15aCH CH N CH O CH.sub.3 CH.sub.3 H L-16aCH CH N CH O CH.sub.3 CH.sub.3 H L-16bCH CH N CH O CH.sub.3 CH.sub.3 H L-18aCH CH N CH O CH.sub.3 CH.sub.3 H L-20aCH CH N CH O CH.sub.3 CH.sub.3 H L-22aCH CH N CH S CH.sub.3 CH.sub.3 H L-1aCH CH N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N CH O OCH.sub.3 CH.sub.3 H L-1aCH CH N CH O OCH.sub.3 CH.sub.3 H L-1bCH CH N CH O OCH.sub.3 CH.sub.3 H L-1cCH CH N CH O OCH.sub.3 CH.sub.3 H L-1dCH CH N CH O OCH.sub.3 CH.sub.3 H L-1eCH CH N CH O OCH.sub.3 CH.sub.3 H L-1fCH CH N CH O OCH.sub.3 CH.sub.3 H L-1gCH CH N CH O OCH.sub.3 CH.sub.3 H L-1hCH CH N CH O OCH.sub.3 CH.sub.3 H L-1iCH CH N CH O OCH.sub.3 CH.sub.3 H L-1jCH CH N CH O OCH.sub.3 CH.sub.3 H L-1kCH CH N CH O OCH.sub.3 CH.sub.3 H L-3aCH CH N CH O OCH.sub.3 CH.sub.3 H L-3bCH CH N CH O OCH.sub.3 CH.sub.3 H L-4aCH CH N CH O OCH.sub.3 CH.sub.3 H L-7aCH CH N CH O OCH.sub.3 CH.sub.3 H L-8aCH CH N CH O OCH.sub.3 CH.sub.3 H L-8bCH CH N CH O OCH.sub.3 CH.sub.3 H L-9aCH CH N CH O OCH.sub.3 CH.sub.3 H L-12aCH CH N CH O OCH.sub.3 CH.sub.3 H L-12bCH CH N CH O OCH.sub.3 CH.sub.3 H L-14aCH CH N CH O OCH.sub.3 CH.sub.3 H L-15aCH CH N CH O OCH.sub.3 CH.sub.3 H L-16aCH CH N CH O OCH.sub.3 CH.sub.3 H L-16bCH CH N CH O OCH.sub.3 CH.sub.3 H L-18aCH CH N CH O OCH.sub.3 CH.sub.3 H L-20aCH CH N CH O OCH.sub.3 CH.sub.3 H L-22aCH CH N CH S OCH.sub.3 CH.sub.3 H L-1aCH CH N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N CH O CH.sub.3 OCH.sub.3 H L-1aCH CH N CH O CH.sub.3 OCH.sub.3 H L-1bCH CH N CH O CH.sub.3 OCH.sub.3 H L-1cCH CH N CH O CH.sub.3 OCH.sub.3 H L-1dCH CH N CH O CH.sub.3 OCH.sub.3 H L-1eCH CH N CH O CH.sub.3 OCH.sub.3 H L-1fCH CH N CH O CH.sub.3 OCH.sub.3 H L-1gCH CH N CH O CH.sub.3 OCH.sub.3 H L-1hCH CH N CH O CH.sub.3 OCH.sub.3 H L-1iCH CH N CH O CH.sub.3 OCH.sub.3 H L-1jCH CH N CH O CH.sub.3 OCH.sub.3 H L-1kCH CH N CH O CH.sub.3 OCH.sub.3 H L-3aCH CH N CH O CH.sub.3 OCH.sub.3 H L-3bCH CH N CH O CH.sub.3 OCH.sub.3 H L-4aCH CH N CH O CH.sub.3 OCH.sub.3 H L-7aCH CH N CH O CH.sub.3 OCH.sub.3 H L-8aCH CH N CH O CH.sub.3 OCH.sub.3 H L-8bCH CH N CH O CH.sub.3 OCH.sub.3 H L-9aCH CH N CH O CH.sub.3 OCH.sub.3 H L-12aCH CH N CH O CH.sub.3 OCH.sub.3 H L-12bCH CH N CH O CH.sub.3 OCH.sub.3 H L-14aCH CH N CH O CH.sub.3 OCH.sub.3 H L-15aCH CH N CH O CH.sub.3 OCH.sub.3 H L-16aCH CH N CH O CH.sub.3 OCH.sub.3 H L-16bCH CH N CH O CH.sub.3 OCH.sub.3 H L-18aCH CH N CH O CH.sub.3 OCH.sub.3 H L-20aCH CH N CH O CH.sub.3 OCH.sub.3 H L-22aCH CH N CH S CH.sub.3 OCH.sub.3 H L-1aCH CH N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1bCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1cCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1dCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1eCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1fCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1gCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1hCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1iCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1jCH CH N CH O OCH.sub.3 OCH.sub.3 H L-1kCH CH N CH O OCH.sub.3 OCH.sub.3 H L-3aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-3bCH CH N CH O OCH.sub.3 OCH.sub.3 H L-4aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-7aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-8aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-8bCH CH N CH O OCH.sub.3 OCH.sub.3 H L-9aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-12aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-12bCH CH N CH O OCH.sub.3 OCH.sub.3 H L-14aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-15aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-16aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-16bCH CH N CH O OCH.sub.3 OCH.sub.3 H L-18aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-20aCH CH N CH O OCH.sub.3 OCH.sub.3 H L-22aCH CH N CH S OCH.sub.3 OCH.sub.3 H L-1aCH CH N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH CH O CH.sub.3 CH.sub.3 H L-1aCH CH CH CH O CH.sub.3 CH.sub.3 H L-1bCH CH CH CH O CH.sub.3 CH.sub.3 H L-1cCH CH CH CH O CH.sub.3 CH.sub.3 H L-1dCH CH CH CH O CH.sub.3 CH.sub.3 H L-1eCH CH CH CH O CH.sub.3 CH.sub.3 H L-1fCH CH CH CH O CH.sub.3 CH.sub.3 H L-1gCH CH CH CH O CH.sub.3 CH.sub.3 H L-1hCH CH CH CH O CH.sub.3 CH.sub.3 H L-1iCH CH CH CH O CH.sub.3 CH.sub.3 H L-1jCH CH CH CH O CH.sub.3 CH.sub.3 H L-1kCH CH CH CH O CH.sub.3 CH.sub.3 H L-3aCH CH CH CH O CH.sub.3 CH.sub.3 H L-3bCH CH CH CH O CH.sub.3 CH.sub.3 H L-4aCH CH CH CH O CH.sub.3 CH.sub.3 H L-7aCH CH CH CH O CH.sub.3 CH.sub.3 H L-8aCH CH CH CH O CH.sub.3 CH.sub.3 H L-8bCH CH CH CH O CH.sub.3 CH.sub.3 H L-9aCH CH CH CH O CH.sub.3 CH.sub.3 H L-12aCH CH CH CH O CH.sub.3 CH.sub.3 H L-12bCH CH CH CH O CH.sub.3 CH.sub.3 H L-14aCH CH CH CH O CH.sub.3 CH.sub.3 H L-15aCH CH CH CH O CH.sub.3 CH.sub.3 H L-16aCH CH CH CH O CH.sub.3 CH.sub.3 H L-16bCH CH CH CH O CH.sub.3 CH.sub.3 H L-18aCH CH CH CH O CH.sub.3 CH.sub.3 H L-20aCH CH CH CH O CH.sub.3 CH.sub.3 H L-22aCH CH CH CH S CH.sub.3 CH.sub.3 H L-1aCH CH CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1bCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1cCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1dCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1eCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1fCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1gCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1hCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1iCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1jCH CH CH CH O OCH.sub.3 CH.sub.3 H L-1kCH CH CH CH O OCH.sub.3 CH.sub.3 H L-3aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-3bCH CH CH CH O OCH.sub.3 CH.sub.3 H L-4aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-7aCH CH CM CH O OCH.sub.3 CH.sub.3 H L-8aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-8bCH CH CH CH O OCH.sub.3 CH.sub. 3 H L-9aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-12bCH CH CH CH O OCH.sub.3 CH.sub.3 H L-14aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-15aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-16aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-16bCH CH CH CH O OCH.sub.3 CH.sub.3 H L-18aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-20aCH CH CH CH O OCH.sub.3 CH.sub.3 H L-22aCH CH CH CH S OCH.sub.3 CH.sub.3 H L-1aCH CH CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1bCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1cCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1dCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1eCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1fCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1gCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1hCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1iCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1jCH CH CH CH O CH.sub.3 OCH.sub.3 H L-1kCH CH CH CH O CH.sub.3 OCH.sub.3 H L-3aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-3bCH CH CH CH O CH.sub.3 OCH.sub.3 H L-4aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-7aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-8aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-8bCH CH CH CH O CH.sub.3 OCH.sub.3 H L-9aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-12bCH CH CH CH O CH.sub.3 OCH.sub.3 H L-14aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-15aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-16aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-16bCH CH CH CH O CH.sub.3 OCH.sub.3 H L-18aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-20aCH CH CH CH O CH.sub.3 OCH.sub.3 H L-22aCH CH CH CH S CH.sub.3 OCH.sub.3 H L-1aCH CH CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1bCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1cCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1dCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1eCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1fCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1gCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1hCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1iCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1jCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-1kCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-3aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-3bCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-4aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-7aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-8aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-8bCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-9aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-12bCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-14aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-15aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-16aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-16bCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-18aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-20aCH CH CH CH O OCH.sub.3 OCH.sub.3 H L-22aCH CH CH CH S OCH.sub.3 OCH.sub.3 H L-1aCH CH CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH CH O CH.sub.3 CH.sub.3 H L-1aN N CH CH O CH.sub.3 CH.sub.3 H L-1bN N CH CH O CH.sub.3 CH.sub.3 H L-1cN N CH CH O CH.sub.3 CH.sub.3 H L-1dN N CH CH O CH.sub.3 CH.sub.3 H L-1eN N CH CH O CH.sub.3 CH.sub.3 H L-1fN N CH CH O CH.sub.3 CH.sub.3 H L-1gN N CH CH O CH.sub.3 CH.sub.3 H L-1hN N CH CH O CH.sub.3 CH.sub.3 H L-1iN N CH CH O CH.sub.3 CH.sub.3 H L-1jN N CH CH O CH.sub.3 CH.sub.3 H L-1kN N CH CH O CH.sub.3 CH.sub.3 H L-3aN N CH CH O CH.sub.3 CH.sub.3 H L-3bN N CH CH O CH.sub.3 CH.sub.3 H L-4aN N CH CH O CH.sub.3 CH.sub.3 H L-7aN N CH CH O CH.sub.3 CH.sub.3 H L-8aN N CH CH O CH.sub.3 CH.sub.3 H L-8bN N CH CH O CH.sub.3 CH.sub.3 H L-9aN N CH CH O CH.sub.3 CH.sub.3 H L-12bN N CH CH O CH.sub.3 CH.sub.3 H L-14aN N CH CH O CH.sub.3 CH.sub.3 H L-15aN N CH CH O CH.sub.3 CH.sub.3 H L-16aN N CH CH O CH.sub.3 CH.sub.3 H L-16bN N CH CH O CH.sub.3 CH.sub.3 H L-18aN N CH CH O CH.sub.3 CH.sub.3 H L-20aN N CH CH O CH.sub.3 CH.sub.3 H L-22aN N CH CH S CH.sub.3 CH.sub.3 H L-1aN N CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH CH O OCH.sub.3 CH.sub.3 H L-1aN N CH CH O OCH.sub.3 CH.sub.3 H L-1bN N CH CH O OCH.sub.3 CH.sub.3 H L-1cN N CH CH O OCH.sub.3 CH.sub.3 H L-1dN N CH CH O OCH.sub.3 CH.sub.3 H L-1eN N CH CH O OCH.sub.3 CH.sub.3 H L-1fN N CH CH O OCH.sub.3 CH.sub.3 H L-1gN N CH CH O OCH.sub.3 CH.sub.3 H L-1hN N CH CH O OCH.sub.3 CH.sub.3 H L-1iN N CH CH O OCH.sub.3 CH.sub.3 H L-1jN N CH CH O OCH.sub.3 CH.sub.3 H L-1kN N CH CH O OCH.sub.3 CH.sub.3 H L-3aN N CH CH O OCH.sub.3 CH.sub.3 H L-3bN N CH CH O OCH.sub.3 CH.sub.3 H L-4aN N CH CH O OCH.sub.3 CH.sub.3 H L-7aN N CH CH O OCH.sub.3 CH.sub.3 H L-8aN N CH CH O OCH.sub.3 CH.sub.3 H L-8bN N CH CH O OCH.sub.3 CH.sub.3 H L-9aN N CH CH O OCH.sub.3 CH.sub.3 H L-12aN N CH CH O OCH.sub.3 CH.sub.3 H L-12bN N CH CH O OCH.sub.3 CH.sub.3 H L-14aN N CH CH O OCH.sub.3 CH.sub.3 H L-15aN N CH CH O OCH.sub.3 CH.sub.3 H L-16aN N CH CH O OCH.sub.3 CH.sub.3 H L-16bN N CH CH O OCH.sub.3 CH.sub.3 H L-18aN N CH CH O OCH.sub.3 CH.sub.3 H L-20aN N CH CH O OCH.sub.3 CH.sub.3 H L-22aN N CH CH S OCH.sub.3 CH.sub.3 H L-1aN N CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH CH O CH.sub.3 OCH.sub.3 H L-1aN N CH CH O CH.sub.3 OCH.sub.3 H L-1bN N CH CH O CH.sub.3 OCH.sub.3 H L-1cN N CH CH O CH.sub. 3 OCH.sub.3 H L-1dN N CH CH O CH.sub.3 OCH.sub.3 H L-1eN N CH CH O CH.sub.3 OCH.sub.3 H L-1fN N CH CH O CH.sub.3 OCH.sub.3 H L-1gN N CH CH O CH.sub.3 OCH.sub.3 H L-1hN N CH CH O CH.sub.3 OCH.sub.3 H L-1iN N CH CH O CH.sub.3 OCH.sub.3 H L-1jN N CH CH O CH.sub.3 OCH.sub.3 H L-1kN N CH CH O CH.sub.3 OCH.sub.3 H L-3aN N CH CH O CH.sub.3 OCH.sub.3 H L-3bN N CH CH O CH.sub.3 OCH.sub.3 H L-4aN N CH CH O CH.sub.3 OCH.sub.3 H L-7aN N CH CH O CH.sub.3 OCH.sub.3 H L-8aN N CH CH O CH.sub.3 OCH.sub.3 H L-8bN N CH CH O CH.sub.3 OCH.sub.3 H L-9aN N CH CH O CH.sub.3 OCH.sub.3 H L-12aN N CH CH O CH.sub.3 OCH.sub.3 H L-12bN N CH CH O CH.sub.3 OCH.sub.3 H L-14aN N CH CH O CH.sub.3 OCH.sub. 3 H L-15aN N CH CH O CH.sub.3 OCH.sub.3 H L-16aN N CH CH O CH.sub.3 OCH.sub.3 H L-16bN N CH CH O CH.sub.3 OCH.sub.3 H L-18aN N CH CH O CH.sub.3 OCH.sub.3 H L-20aN N CH CH O CH.sub.3 OCH.sub.3 H L-22aN N CH CH S CH.sub.3 OCH.sub.3 H L-1aN N CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH CH O OCH.sub.3 OCH.sub.3 H L-1aN N CH CH O OCH.sub.3 OCH.sub.3 H L-1bN N CH CH O OCH.sub.3 OCH.sub.3 H L-1cN N CH CH O OCH.sub.3 OCH.sub.3 H L-1dN N CH CH O OCH.sub.3 OCH.sub.3 H L-1eN N CH CH O OCH.sub.3 OCH.sub.3 H L-1fN N CH CH O OCH.sub.3 OCH.sub.3 H L-1gN N CH CH O OCH.sub.3 OCH.sub.3 H L-1hN N CH CH O OCH.sub.3 OCH.sub.3 H L-1iN N CH CH O OCH.sub.3 OCH.sub.3 H L-1jN N CH CH O OCH.sub.3 OCH.sub.3 H L-1kN N CH CH O OCH.sub.3 OCH.sub.3 H L-3aN N CH CH O OCH.sub.3 OCH.sub.3 H L-3bN N CH CH O OCH.sub.3 OCH.sub.3 H L-4aN N CH CH O OCH.sub.3 OCH.sub.3 H L-7aN N CH CH O OCH.sub.3 OCH.sub.3 H L-8aN N CH CH O OCH.sub.3 OCH.sub.3 H L-8bN N CH CH O OCH.sub.3 OCH.sub.3 H L-9aN N CH CH O OCH.sub.3 OCH.sub.3 H L-12aN N CH CH O OCH.sub.3 OCH.sub.3 H L-12bN N CH CH O OCH.sub.3 OCH.sub.3 H L-14aN N CH CH O OCH.sub.3 OCH.sub.3 H L-15aN N CH CH O OCH.sub.3 OCH.sub.3 H L-16aN N CH CH O OCH.sub.3 OCH.sub.3 H L-16bN N CH CH O OCH.sub.3 OCH.sub.3 H L-18aN N CH CH O OCH.sub.3 OCH.sub.3 H L-20aN N CH CH O OCH.sub.3 OCH.sub.3 H L-22aN N CH CH S OCH.sub.3 OCH.sub.3 H L-1aN N CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N N CH O CH.sub.3 CH.sub.3 H L-1aN N N CH O CH.sub.3 CH.sub.3 H L-1bN N N CH O CH.sub.3 CH.sub.3 H L-1cN N N CH O CH.sub.3 CH.sub.3 H L-1dN N N CH O CH.sub.3 CH.sub.3 H L-1eN N N CH O CH.sub.3 CH.sub.3 H L-1fN N N CH O CH.sub.3 CH.sub.3 H L-1gN N N CH O CH.sub.3 CH.sub.3 H L-1hN N N CH O CH.sub.3 CH.sub.3 H L-1iN N N CH O CH.sub.3 CH.sub.3 H L-1jN N N CH O CH.sub.3 CH.sub.3 H L-1kN N N CH O CH.sub.3 CH.sub.3 H L-3aN N N CH O CH.sub.3 CH.sub.3 H L-3bN N N CH O CH.sub.3 CH.sub.3 H L-4aN N N CH O CH.sub.3 CH.sub.3 H L-7aN N N CH O CH.sub.3 CH.sub.3 H L-8aN N N CH O CH.sub.3 CH.sub.3 H L-8bN N N CH O CH.sub.3 CH.sub.3 H L-9aN N N CH O CH.sub.3 CH.sub.3 H L-12bN N N CH O CH.sub.3 CH.sub.3 H L-14aN N N CH O CH.sub.3 CH.sub.3 H L-15aN N N CH O CH.sub.3 CH.sub.3 H L-16aN N N CH O CH.sub.3 CH.sub.3 H L-16bN N N CH O CH.sub.3 CH.sub.3 H L-18aN N N CH O CH.sub.3 CH.sub.3 H L-20aN N N CH O CH.sub.3 CH.sub.3 H L-22aN N N CH S CH.sub.3 CH.sub.3 H L-1aN N N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N N CH O OCH.sub.3 CH.sub.3 H L-1aN N N CH O OCH.sub.3 CH.sub.3 H L-1bN N N CH O OCH.sub.3 CH.sub.3 H L-1cN N N CH O OCH.sub.3 CH.sub.3 H L-1dN N N CH O OCH.sub.3 CH.sub.3 H L-1eN N N CH O OCH.sub.3 CH.sub.3 H L-1fN N N CH O OCH.sub.3 CH.sub.3 H L-1gN N N CH O OCH.sub.3 CH.sub.3 H L-1hN N N CH O OCH.sub.3 CH.sub.3 H L-1iN N N CH O OCH.sub.3 CH.sub.3 H L-1jN N N CH O OCH.sub.3 CH.sub.3 H L-1kN N N CH O OCH.sub.3 CH.sub.3 H L-3aN N N CH O OCH.sub.3 CH.sub.3 H L-3bN N N CH O OCH.sub.3 CH.sub.3 H L-4aN N N CH O OCH.sub.3 CH.sub.3 H L-7aN N N CH O OCH.sub.3 CH.sub.3 H L-8aN N N CH O OCH.sub.3 CH.sub.3 H L-8bN N N CH O OCH.sub.3 CH.sub.3 H L-9aN N N CH O OCH.sub.3 CH.sub.3 H L-12aN N N CH O OCH.sub.3 CH.sub.3 H L-12bN N N CH O OCH.sub.3 CH.sub.3 H L-14aN N N CH O OCH.sub.3 CH.sub.3 H L-15aN N N CH O OCH.sub.3 CH.sub.3 H L-16aN N N CH O OCH.sub.3 CH.sub.3 H L-16bN N N CH O OCH.sub.3 CH.sub.3 H L-18aN N N CH O OCH.sub.3 CH.sub.3 H L-20aN N N CH O OCH.sub.3 CH.sub.3 H L-22aN N N CH S OCH.sub.3 CH.sub.3 H L-1aN N N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N N CH O CH.sub.3 OCH.sub.3 H L-1aN N N CH O CH.sub.3 OCH.sub.3 H L-1bN N N CH O CH.sub.3 OCH.sub.3 H L-1cN N N CH O CH.sub.3 OCH.sub.3 H L-1dN N N CH O CH.sub.3 OCH.sub.3 H L-1eN N N CH O CH.sub.3 OCH.sub.3 H L-1fN N N CH O CH.sub.3 OCH.sub.3 H L-1gN N N CH O CH.sub.3 OCH.sub.3 H L-1hN N N CH O CH.sub.3 OCH.sub.3 H L-1iN N N CH O CH.sub.3 OCH.sub.3 H L-1jN N N CH O CH.sub.3 OCH.sub.3 H L-1kN N N CH O CH.sub.3 OCH.sub.3 H L-3aN N N CH O CH.sub.3 OCH.sub.3 H L-3bN N N CH O CH.sub.3 OCH.sub.3 H L-4aN N N CH O CH.sub.3 OCH.sub.3 H L-7aN N N CH O CH.sub.3 OCH.sub.3 H L-8aN N N CH O CH.sub.3 OCH.sub.3 H L-8bN N N CH O CH.sub.3 OCH.sub.3 H L-9aN N N CH O CH.sub.3 OCH.sub.3 H L-12aN N N CH O CH.sub.3 OCH.sub.3 H L-12bN N N CH O CH.sub.3 OCH.sub.3 H L-14aN N N CH O CH.sub.3 OCH.sub.3 H L-15aN N N CH O CH.sub.3 OCH.sub.3 H L-16aN N N CH O CH.sub.3 OCH.sub.3 H L-16bN N N CH O CH.sub.3 OCH.sub.3 H L-18aN N N CH O CH.sub.3 OCH.sub.3 H L-20aN N N CH O CH.sub.3 OCH.sub.3 H L-22aN N N CH S CH.sub.3 OCH.sub.3 H L-1aN N N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N N CH O CH.sub.3 OCH.sub.3 H L-1aN N N CH O OCH.sub.3 OCH.sub.3 H L-1bN N N CH O OCH.sub.3 OCH.sub.3 H L-1cN N N CH O OCH.sub.3 OCH.sub.3 H L-1dN N N CH O OCH.sub.3 OCH.sub.3 H L-1eN N N CH O OCH.sub.3 OCH.sub.3 H L-1fN N N CH O OCH.sub.3 OCH.sub.3 H L-1gN N N CH O OCH.sub.3 OCH.sub.3 H L-1hN N N CH O OCH.sub.3 OCH.sub.3 H L-1iN N N CH O OCH.sub.3 OCH.sub.3 H L-1jN N N CH O OCH.sub.3 OCH.sub.3 H L-1kN N N CH O OCH.sub.3 OCH.sub.3 H L-3aN N N CH O OCH.sub.3 OCH.sub.3 H L-3bN N N CH O OCH.sub.3 OCH.sub.3 H L-4aN N N CH O OCH.sub.3 OCH.sub.3 H L-7aN N N CH O OCH.sub.3 OCH.sub.3 H L-8aN N N CH O OCH.sub.3 OCH.sub.3 H L-8bN N N CH O OCH.sub.3 OCH.sub.3 H L-9aN N N CH O OCH.sub.3 OCH.sub.3 H L-12aN N N CH O OCH.sub.3 OCH.sub.3 H L-12bN N N CH O OCH.sub.3 OCH.sub.3 H L-14aN N N CH O OCH.sub.3 OCH.sub.3 H L-15aN N N CH O OCH.sub.3 OCH.sub.3 H L-16aN N N CH O OCH.sub.3 OCH.sub.3 H L-16bN N N CH O OCH.sub.3 OCH.sub.3 H L-18aN N N CH O OCH.sub.3 OCH.sub.3 H L-20aN N N CH O OCH.sub.3 OCH.sub.3 H L-22aN N N CH S OCH.sub.3 OCH.sub.3 H L-1aN N N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N CH O CH.sub.3 CH.sub.3 H L-1aN CH N CH O CH.sub.3 CH.sub.3 H L-1bN CH N CH O CH.sub.3 CH.sub.3 H L-1cN CH N CH O CH.sub.3 CH.sub.3 H L-1dN CH N CH O CH.sub.3 CH.sub.3 H L-1eN CH N CH O CH.sub.3 CH.sub.3 H L-1fN CH N CH O CH.sub.3 CH.sub.3 H L-1gN CH N CH O CH.sub.3 CH.sub.3 H L-1hN CH N CH O CH.sub.3 CH.sub.3 H L-1iN CH N CH O CH.sub.3 CH.sub.3 H L-1jN CH N CH O CH.sub.3 CH.sub.3 H L-1kN CH N CH O CH.sub.3 CH.sub.3 H L-3aN CH N CH O CH.sub.3 CH.sub.3 H L-3bN CH N CH O CH.sub.3 CH.sub.3 H L-4aN CH N CH O CH.sub.3 CH.sub.3 H L-7aN CH N CH O CH.sub.3 CH.sub.3 H L-8aN CH N CH O CH.sub.3 CH.sub.3 H L-8bN CH N CH O CH.sub.3 CH.sub.3 H L-9aN CH N CH O CH.sub.3 CH.sub.3 H L-12bN CH N CH O CH.sub.3 CH.sub.3 H L-14aN CH N CH O CH.sub.3 CH.sub.3 H L-15aN CH N CH O CH.sub.3 CH.sub.3 H L-16aN CH N CH O CH.sub.3 CH.sub.3 H L-16bN CH N CH O CH.sub.3 CH.sub.3 H L-18aN CH N CH O CH.sub.3 CH.sub.3 H L-20aN CH N CH O CH.sub.3 CH.sub.3 H L-22aN CH N CH S CH.sub.3 CH.sub.3 H L-1aN CH N CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N CH O OCH.sub.3 CH.sub.3 H L-1aN CH N CH O OCH.sub.3 CH.sub.3 H L-1bN CH N CH O OCH.sub.3 CH.sub.3 H L-1cN CH N CH O OCH.sub.3 CH.sub.3 H L-1dN CH N CH O OCH.sub.3 CH.sub.3 H L-1eN CH N CH O OCH.sub.3 CH.sub.3 H L-1fN CH N CH O OCH.sub.3 CH.sub.3 H L-1gN CH N CH O OCH.sub.3 CH.sub.3 H L-1hN CH N CH O OCH.sub.3 CH.sub.3 H L-1iN CH N CH O OCH.sub.3 CH.sub.3 H L-1jN CH N CH O OCH.sub.3 CH.sub.3 H L-1kN CH N CH O OCH.sub.3 CH.sub.3 H L-3aN CH N CH O OCH.sub.3 CH.sub.3 H L-3bN CH N CH O OCH.sub.3 CH.sub.3 H L-4aN CH N CH O OCH.sub.3 CH.sub.3 H L-7aN CH N CH O OCH.sub.3 CH.sub.3 H L-8aN CH N CH O OCH.sub.3 CH.sub.3 H L-8bN CH N CH O OCH.sub.3 CH.sub.3 H L-9aN CH N CH O OCH.sub.3 CH.sub.3 H L-12aN CH N CH O OCH.sub.3 CH.sub.3 H L-12bN CH N CH O OCH.sub.3 CH.sub.3 H L-14aN CH N CH O OCH.sub.3 CH.sub.3 H L-15aN CH N CH O OCH.sub.3 CH.sub.3 H L-16aN CH N CH O OCH.sub.3 CH.sub.3 H L-16bN CH N CH O OCH.sub.3 CH.sub.3 H L-18aN CH N CH O OCH.sub.3 CH.sub.3 H L-20aN CH N CH O OCH.sub.3 CH.sub.3 H L-22aN CH N CH S OCH.sub.3 CH.sub.3 H L-1aN CH N CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N CH O CH.sub.3 OCH.sub.3 H L-1aN CH N CH O CH.sub.3 OCH.sub.3 H L-1bN CH N CH O CH.sub.3 OCH.sub.3 H L-1cN CH N CH O CH.sub.3 OCH.sub.3 H L-1dN CH N CH O CH.sub.3 OCH.sub.3 H L-1eN CH N CH O CH.sub.3 OCH.sub.3 H L-1fN CH N CH O CH.sub.3 OCH.sub.3 H L-1gN CH N CH O CH.sub.3 OCH.sub.3 H L-1hN CH N CH O CH.sub.3 OCH.sub.3 H L-1iN CH N CH O CH.sub.3 OCH.sub.3 H L-1jN CH N CH O CH.sub.3 OCH.sub.3 H L-1kN CH N CH O CH.sub.3 OCH.sub.3 H L-3aN CH N CH O CH.sub.3 OCH.sub.3 H L-3bN CH N CH O CH.sub.3 OCH.sub.3 H L-4aN CH N CH O CH.sub.3 OCH.sub.3 H L-7aN CH N CH O CH.sub.3 OCH.sub.3 H L-8aN CH N CH O CH.sub.3 OCH.sub.3 H L-8bN CH N CH O CH.sub.3 OCH.sub.3 H L-9aN CH N CH O CH.sub.3 OCH.sub.3 H L-12aN CH N CH O CH.sub.3 OCH.sub.3 H L-12bN CH N CH O CH.sub.3 OCH.sub.3 H L-14aN CH N CH O CH.sub.3 OCH.sub.3 H L-15aN CH N CH O CH.sub.3 OCH.sub.3 H L-16aN CH N CH O CH.sub.3 OCH.sub.3 H L-16bN CH N CH O CH.sub.3 OCH.sub.3 H L-18aN CH N CH O CH.sub.3 OCH.sub.3 H L-20aN CH N CH O CH.sub.3 OCH.sub.3 H L-22aN CH N CH S CH.sub.3 OCH.sub.3 H L-1aN CH N CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N CH O OCH.sub.3 OCH.sub.3 H L-1aN CH N CH O OCH.sub.3 OCH.sub.3 H L-1bN CH N CH O OCH.sub.3 OCH.sub.3 H L-1cN CH N CH O OCH.sub.3 OCH.sub.3 H L-1dN CH N CH O OCH.sub.3 OCH.sub.3 H L-1eN CH N CH O OCH.sub.3 OCH.sub.3 H L-1fN CH N CH O OCH.sub.3 OCH.sub.3 H L-1gN CH N CH O OCH.sub.3 OCH.sub.3 H L-1hN CH N CH O OCH.sub.3 OCH.sub.3 H L-1iN CH N CH O OCH.sub.3 OCH.sub.3 H L-1jN CH N CH O OCH.sub.3 OCH.sub.3 H L-1kN CH N CH O OCH.sub.3 OCH.sub.3 H L-3aN CH N CH O OCH.sub.3 OCH.sub.3 H L-3bN CH N CH O OCH.sub.3 OCH.sub.3 H L-4aN CH N CH O OCH.sub.3 OCH.sub.3 H L-7aN CH N CH O OCH.sub.3 OCH.sub.3 H L-8aN CH N CH O OCH.sub.3 OCH.sub.3 H L-8bN CH N CH O OCH.sub.3 OCH.sub.3 H L-9aN CH N CH O OCH.sub.3 OCH.sub.3 H L-12aN CH N CH O OCH.sub.3 OCH.sub.3 H L-12bN CH N CH O CH.sub.3 OCH.sub.3 H L-14aN CH N CH O OCH.sub.3 OCH.sub.3 H L-15aN CH N CH O OCH.sub.3 OCH.sub.3 H L-16aN CH N CH O OCH.sub.3 OCH.sub.3 H L-16bN CH N CH O OCH.sub.3 OCH.sub.3 H L-18aN CH N CH O OCH.sub.3 OCH.sub.3 H L-20aN CH N CH O OCH.sub.3 OCH.sub.3 H L-22aN CH N CH S OCH.sub.3 OCH.sub.3 H L-1aN CH N CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH CH O CH.sub.3 CH.sub.3 H L-1aN CH CH CH O CH.sub.3 CH.sub.3 H L-1bN CH CH CH O CH.sub.3 CH.sub.3 H L-1cN CH CH CH O CH.sub.3 CH.sub.3 H L-1dN CH CH CH O CH.sub.3 CH.sub.3 H L-1eN CH CH CH O CH.sub.3 CH.sub.3 H L-1fN CH CH CH O CH.sub.3 CH.sub.3 H L-1gN CH CH CH O CH.sub.3 CH.sub.3 H L-1hN CH CH CH O CH.sub.3 CH.sub.3 H L-1iN CH CH CH O CH.sub.3 CH.sub.3 H L-1jN CH CH CH O CH.sub.3 CH.sub.3 H L-1kN CH CH CH O CH.sub.3 CH.sub.3 H L-3aN CH CH CH O CH.sub.3 CH.sub.3 H L-3bN CH CH CH O CH.sub.3 CH.sub.3 H L-4aN CH CH CH O CH.sub.3 CH.sub.3 H L-7aN CH CH CH O CH.sub.3 CH.sub.3 H L-8aN CH CH CH O CH.sub.3 CH.sub.3 H L-8bN CH CH CH O CH.sub.3 CH.sub.3 H L-9aN CH CH CH O CH.sub.3 CH.sub.3 H L-12bN CH CH CH O CH.sub.3 CH.sub.3 H L-14aN CH CH CH O CH.sub.3 CH.sub.3 H L-15aN CH CH CH O CH.sub.3 CH.sub.3 H L-16aN CH CH CH O CH.sub.3 CH.sub.3 H L-16bN CH CH CH O CH.sub.3 CH.sub.3 H L-18aN CH CH CH O CH.sub.3 CH.sub.3 H L-20aN CH CH CH O CH.sub.3 CH.sub.3 H L-22aN CH CH CH S CH.sub.3 CH.sub.3 H L-1aN CH CH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH CH O OCH.sub.3 CH.sub.3 H L-1aN CH CH CH O OCH.sub.3 CH.sub.3 H L-1bN CH CH CH O OCH.sub.3 CH.sub.3 H L-1cN CH CH CH O OCH.sub.3 CH.sub.3 H L-1dN CH CH CH O OCH.sub.3 CH.sub.3 H L-1eN CH CH CH O OCH.sub.3 CH.sub.3 H L-1fN CH CH CH O OCH.sub.3 CH.sub.3 H L-1gN CH CH CH O OCH.sub.3 CH.sub.3 H L-1hN CH CH CH O OCH.sub.3 CH.sub.3 H L-1iN CH CH CH O OCH.sub.3 CH.sub.3 H L-1jN CH CH CH O OCH.sub.3 CH.sub.3 H L-1kN CH CH CH O OCH.sub.3 CH.sub.3 H L-3aN CH CH CH O OCH.sub.3 CH.sub.3 H L-3bN CH CH CH O OCH.sub.3 CH.sub. 3 H L-4aN CH CH CH O OCH.sub.3 CH.sub.3 H L-7aN CH CH CH O OCH.sub.3 CH.sub.3 H L-8aN CH CH CH O OCH.sub.3 CH.sub.3 H L-8bN CH CH CH O OCH.sub.3 CH.sub.3 H L-9aN CH CH CH O OCH.sub.3 CH.sub.3 H L-12aN CH CH CH O OCH.sub.3 CH.sub.3 H L-12bN CH CH CH O OCH.sub.3 CH.sub.3 H L-14aN CH CH CH O OCH.sub.3 CH.sub.3 H L-15aN CH CH CH O OCH.sub.3 CH.sub.3 H L-16aN CH CH CH O OCH.sub.3 CH.sub.3 H L-16bN CH CH CH O OCH.sub.3 CH.sub.3 H L-18aN CH CH CH O OCH.sub.3 CH.sub.3 H L-20aN CH CH CH O OCH.sub.3 CH.sub.3 H L-22aN CH CH CH S OCH.sub.3 CH.sub.3 H L-1aN CH CH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH CH O CH.sub.3 OCH.sub.3 H L-1aN CH CH CH O CH.sub.3 OCH.sub.3 H L-1bN CH CH CH O CH.sub.3 OCH.sub.3 H L-1cN CH CH CH O CH.sub.3 OCH.sub.3 H L-1dN CH CH CH O CH.sub.3 OCH.sub.3 H L-1eN CH CH CH O CH.sub.3 OCH.sub.3 H L-1fN CH CH CH O CH.sub.3 OCH.sub.3 H L-1gN CH CH CH O CH.sub.3 OCH.sub.3 H L-1hN CH CH CH O CH.sub.3 OCH.sub.3 H L-1iN CH CH CH O CH.sub.3 OCH.sub.3 H L-1jN CH CH CH O CH.sub.3 OCH.sub.3 H L-1kN CH CH CH O CH.sub.3 OCH.sub.3 H L-3aN CH CH CH O CH.sub.3 OCH.sub.3 H L-3bN CH CH CH O CH.sub.3 OCH.sub.3 H L-4aN CH CH CH O CH.sub.3 OCH.sub.3 H L-7aN CH CH CH O CH.sub.3 OCH.sub.3 H L-8aN CH CH CH O CH.sub.3 OCH.sub.3 H L-8bN CH CH CH O CH.sub.3 OCH.sub.3 H L-9aN CH CH CH O CH.sub.3 OCH.sub.3 H L-12aN CH CH CH O CH.sub.3 OCH.sub.3 H L-12bN CH CH CH O CH.sub.3 OCH.sub.3 H L-14aN CH CH CH O CH.sub.3 OCH.sub.3 H L-15aN CH CH CH O CH.sub.3 OCH.sub.3 H L-16aN CH CH CH O CH.sub.3 OCH.sub.3 H L-16bN CH CH CH O CH.sub.3 OCH.sub.3 H L-18aN CH CH CH O CH.sub.3 OCH.sub.3 H L-20aN CH CH CH O CH.sub.3 OCH.sub.3 H L-22aN CH CH CH S CH.sub.3 OCH.sub.3 H L-1aN CH CH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-1aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-1b 284- 287N CH CH CH O OCH.sub.3 OCH.sub.3 H L-1c 223- 226N CH CH CH O OCH.sub.3 OCH.sub.3 H L-1d 277- 279N CH CH CH O OCH.sub.3 OCH.sub.3 H L-1eN CH CH CH O OCH.sub.3 OCH.sub.3 H L-1fN CH CH CH O OCH.sub.3 OCH.sub. 3 H L-1gN CH CH CH O OCH.sub.3 OCH.sub.3 H L-1hN CH CH CH O OCH.sub.3 OCH.sub.3 H L-1iN CH CH CH O OCH.sub.3 OCH.sub.3 H L-1jN CH CH CH O OCH.sub.3 OCH.sub.3 H L-1kN CH CH CH O OCH.sub.3 OCH.sub.3 H L-3aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-3bN CH CH CH O OCH.sub.3 OCH.sub.3 H L-4aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-7aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-8aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-8bN CH CH CH O OCH.sub.3 OCH.sub.3 H L-9aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-12aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-12bN CH CH CH O OCH.sub.3 OCH.sub.3 H L-14aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-15aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-16a 295- 296N CH CH CH O OCH.sub.3 OCH.sub.3 H L-16bN CH CH CH O OCH.sub.3 OCH.sub.3 H L-18aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-20aN CH CH CH O OCH.sub.3 OCH.sub.3 H L-22aN CH CH CH S OCH.sub.3 OCH.sub.3 H L-1aN CH CH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N CH N O CH.sub.3 CH.sub.3 H L-1aCH N CH N O CH.sub.3 CH.sub.3 H L-1bCH N CH N O CH.sub.3 CH.sub.3 H L-1cCH N CH N O CH.sub.3 CH.sub.3 H L-1dCH N CH N O CH.sub.3 CH.sub.3 H L-1eCH N CH N O CH.sub.3 CH.sub.3 H L-1fCH N CH N O CH.sub.3 CH.sub.3 H L-1gCH N CH N O CH.sub.3 CH.sub.3 H L-1hCH N CH N O CH.sub.3 CH.sub.3 H L-1iCH N CH N O CH.sub.3 CH.sub.3 H L-1jCH N CH N O CH.sub.3 CH.sub.3 H L-1kCH N CH N O CH.sub.3 CH.sub.3 H L-3aCH N CH N O CH.sub.3 CH.sub.3 H L-3bCH N CH N O CH.sub.3 CH.sub.3 H L-4aCH N CH N O CH.sub.3 CH.sub.3 H L-7aCH N CH N O CH.sub.3 CH.sub.3 H L-8aCH N CH N O CH.sub.3 CH.sub.3 H L-8bCH N CH N O CH.sub.3 CH.sub.3 H L-9aCH N CH N O CH.sub.3 CH.sub.3 H L-12aCH N CH N O CH.sub.3 CH.sub.3 H L-12bCH N CH N O CH.sub.3 CH.sub.3 H L-14aCH N CH N O CH.sub.3 CH.sub.3 H L-15aCH N CH N O CH.sub.3 CH.sub.3 H L-16aCH N CH N O CH.sub.3 CH.sub.3 H L-16bCH N CH N O CH.sub.3 CH.sub.3 H L-18aCH N CH N O CH.sub.3 CH.sub.3 H L-20aCH N CH N O CH.sub.3 CH.sub.3 H L-22aCH N CH N S CH.sub.3 CH.sub.3 H L-1aCH N CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH N O OCH.sub.3 CH.sub.3 H L-1aCH N CH N O OCH.sub.3 CH.sub.3 H L-1bCH N CH N O OCH.sub.3 CH.sub.3 H L-1cCH N CH N O OCH.sub.3 CH.sub.3 H L-1dCH N CH N O OCH.sub.3 CH.sub.3 H L-1eCH N CH N O OCH.sub.3 CH.sub.3 H L-1fCH N CH N O OCH.sub.3 CH.sub.3 H L-1gCH N CH N O OCH.sub.3 CH.sub.3 H L-1hCH N CH N O OCH.sub.3 CH.sub.3 H L-1iCH N CH N O OCH.sub.3 CH.sub.3 H L-1jCH N CH N O OCH.sub.3 CH.sub.3 H L-1kCH N CH N O OCH.sub.3 CH.sub.3 H L-3aCH N CH N O OCH.sub.3 CH.sub.3 H L-3bCH N CH N O OCH.sub.3 CH.sub.3 H L-4aCH N CH N O OCH.sub.3 CH.sub.3 H L-7aCH N CH N O OCH.sub.3 CH.sub.3 H L-8aCH N CH N O OCH.sub.3 CH.sub.3 H L-8bCH N CH N O OCH.sub.3 CH.sub.3 H L-9aCH N CH N O OCH.sub.3 CH.sub.3 H L-12aCH N CH N O OCH.sub.3 CH.sub.3 H L-12bCH N CH N O OCH.sub.3 CH.sub.3 H L-14aCH N CH N O OCH.sub.3 CH.sub.3 H L-15aCH N CH N O OCH.sub.3 CH.sub.3 H L-16aCH N CH N O OCH.sub.3 CH.sub.3 H L-16bCH N CH N O OCH.sub.3 CH.sub.3 H L-18aCH N CH N O OCH.sub.3 CH.sub.3 H L-20aCH N CH N O OCH.sub.3 CH.sub.3 H L-22aCH N CH N S OCH.sub.3 CH.sub.3 H L-1aCH N CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH N O CH.sub.3 OCH.sub.3 H L-1aCH N CH N O CH.sub.3 OCH.sub.3 H L-1bCH N CH N O CH.sub.3 OCH.sub.3 H L-1cCH N CH N O CH.sub.3 OCH.sub.3 H L-1dCH N CH N O CH.sub.3 OCH.sub.3 H L-1eCH N CH N O CH.sub.3 OCH.sub.3 H L-1fCH N CH N O CH.sub.3 OCH.sub.3 H L-1gCH N CH N O CH.sub.3 OCH.sub.3 H L-1hCH N CH N O CH.sub.3 OCH.sub.3 H L-1iCH N CH N O CH.sub.3 OCH.sub.3 H L-1jCH N CH N O CH.sub.3 OCH.sub.3 H L-1kCH N CH N O CH.sub.3 OCH.sub.3 H L-3aCH N CH N O CH.sub.3 OCH.sub.3 H L-3bCH N CH N O CH.sub.3 OCH.sub.3 H L-4aCH N CH N O CH.sub.3 OCH.sub.3 H L-7aCH N CH N O CH.sub.3 OCH.sub.3 H L-8aCH N CH N O CH.sub.3 OCH.sub.3 H L-8bCH N CH N O CH.sub.3 OCH.sub.3 H L-9aCH N CH N O CH.sub.3 OCH.sub.3 H L-12aCH N CH N O CH.sub.3 OCH.sub.3 H L-12bCH N CH N O CH.sub.3 OCH.sub.3 H L-14aCH N CH N O CH.sub.3 OCH.sub.3 H L-15aCH N CH N O CH.sub.3 OCH.sub.3 H L-16aCH N CH N O CH.sub.3 OCH.sub.3 H L-16bCH N CH N O CH.sub.3 OCH.sub.3 H L-18aCH N CH N O CH.sub.3 OCH.sub.3 H L-20aCH N CH N O CH.sub.3 OCH.sub.3 H L-22aCH N CH N S CH.sub.3 OCH.sub.3 H L-1aCH N CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N CH N O OCH.sub.3 OCH.sub.3 H L-1aCH N CH N O OCH.sub.3 OCH.sub.3 H L-1bCH N CH N O OCH.sub.3 OCH.sub.3 H L-1cCH N CH N O OCH.sub.3 OCH.sub.3 H L-1dCH N CH N O OCH.sub.3 OCH.sub.3 H L-1eCH N CH N O OCH.sub.3 OCH.sub.3 H L-1fCH N CH N O OCH.sub.3 OCH.sub.3 H L-1gCH N CH N O OCH.sub.3 OCH.sub.3 H L-1hCH N CH N O OCH.sub.3 OCH.sub.3 H L-1iCH N CH N O OCH.sub.3 OCH.sub.3 H L-1jCH N CH N O OCH.sub.3 OCH.sub.3 H L-1kCH N CH N O OCH.sub.3 OCH.sub.3 H L-3aCH N CH N O OCH.sub.3 OCH.sub.3 H L-3bCH N CH N O OCH.sub.3 OCH.sub.3 H L-4aCH N CH N O OCH.sub.3 OCH.sub.3 H L-7aCH N CH N O OCH.sub.3 OCH.sub.3 H L-8aCH N CH N O OCH.sub. 3 OCH.sub.3 H L-8bCH N CH N O OCH.sub.3 OCH.sub.3 H L-9aCH N CH N O OCH.sub.3 OCH.sub.3 H L-12aCH N CH N O OCH.sub.3 OCH.sub.3 H L-12bCH N CH N O OCH.sub.3 OCH.sub.3 H L-14aCH N CH N O OCH.sub.3 OCH.sub.3 H L-15aCH N CH N O OCH.sub.3 OCH.sub.3 H L-16aCH N CH N O OCH.sub.3 OCH.sub.3 H L-16bCH N CH N O OCH.sub.3 OCH.sub.3 H L-18aCH N CH N O OCH.sub.3 OCH.sub.3 H L-20aCH N CH N O OCH.sub.3 OCH.sub.3 H L-22aCH N CH N S OCH.sub.3 OCH.sub.3 H L-1aCH N CH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N N O CH.sub.3 CH.sub.3 H L-1aCH CH N N O CH.sub.3 CH.sub.3 H L-1bCH CH N N O CH.sub.3 CH.sub.3 H L-1cCH CH N N O CH.sub.3 CH.sub.3 H L-1dCH CH N N O CH.sub.3 CH.sub.3 H L-1eCH CH N N O CH.sub.3 CH.sub.3 H L-1fCH CH N N O CH.sub.3 CH.sub.3 H L-1gCH CH N N O CH.sub.3 CH.sub.3 H L-1hCH CH N N O CH.sub.3 CH.sub.3 H L-1iCH CH N N O CH.sub.3 CH.sub.3 H L-1jCH CH N N O CH.sub.3 CH.sub.3 H L-1kCH CH N N O CH.sub.3 CH.sub.3 H L-3aCH CH N N O CH.sub.3 CH.sub.3 H L-3bCH CH N N O CH.sub.3 CH.sub.3 H L-4aCH CH N N O CH.sub.3 CH.sub.3 H L-7aCH CH N N O CH.sub.3 CH.sub.3 H L-8aCH CH N N O CH.sub.3 CH.sub.3 H L-8bCH CH N N O CH.sub.3 CH.sub.3 H L-9aCH CH N N O CH.sub.3 CH.sub.3 H L-12aCH CH N N O CH.sub.3 CH.sub.3 H L-12bCH CH N N O CH.sub.3 CH.sub.3 H L-14aCH CH N N O CH.sub.3 CH.sub.3 H L-15aCH CH N N O CH.sub.3 CH.sub.3 H L-16aCH CH N N O CH.sub.3 CH.sub.3 H L-16bCH CH N N O CH.sub.3 CH.sub.3 H L-18aCH CH N N O CH.sub.3 CH.sub.3 H L-20aCH CH N N O CH.sub.3 CH.sub.3 H L-22aCH CH N N S CH.sub.3 CH.sub.3 H L-1aCH CH N N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N N O OCH.sub.3 CH.sub.3 H L-1aCH CH N N O OCH.sub.3 CH.sub.3 H L-1bCH CH N N O OCH.sub.3 CH.sub.3 H L-1cCH CH N N O OCH.sub.3 CH.sub.3 H L-1dCH CH N N O OCH.sub.3 CH.sub.3 H L-1eCH CH N N O OCH.sub.3 CH.sub.3 H L-1fCH CH N N O OCH.sub.3 CH.sub.3 H L-1gCH CH N N O OCH.sub.3 CH.sub.3 H L-1hCH CH N N O OCH.sub.3 CH.sub.3 H L-1iCH CH N N O OCH.sub.3 CH.sub.3 H L-1jCH CH N N O OCH.sub.3 CH.sub.3 H L-1kCH CH N N O OCH.sub.3 CH.sub.3 H L-3aCH CH N N O OCH.sub.3 CH.sub.3 H L-3bCH CH N N O OCH.sub.3 CH.sub.3 H L-4aCH CH N N O OCH.sub.3 CH.sub.3 H L-7aCH CH N N O OCH.sub.3 CH.sub.3 H L-8aCH CH N N O OCH.sub.3 CH.sub.3 H L-8bCH CH N N O OCH.sub.3 CH.sub.3 H L-9aCH CH N N O OCH.sub.3 CH.sub.3 H L-12bCH CH N N O OCH.sub.3 CH.sub.3 H L-14aCH CH N N O OCH.sub.3 CH.sub.3 H L-15aCH CH N N O OCH.sub.3 CH.sub.3 H L-16aCH CH N N O OCH.sub.3 CH.sub.3 H L-16bCH CH N N O OCH.sub.3 CH.sub.3 H L-18aCH CH N N O OCH.sub.3 CH.sub.3 H L-20aCH CH N N O OCH.sub.3 CH.sub.3 H L-22aCH CH N N S OCH.sub.3 CH.sub.3 H L-1aCH CH N N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH N N O CH.sub.3 OCH.sub.3 H L-1aCH CH N N O CH.sub.3 OCH.sub.3 H L-1bCH CH N N O CH.sub.3 OCH.sub.3 H L-1cCH CH N N O CH.sub.3 OCH.sub.3 H L-1dCH CH N N O CH.sub.3 OCH.sub.3 H L-1eCH CH N N O CH.sub.3 OCH.sub.3 H L-1fCH CH N N O CH.sub.3 OCH.sub.3 H L-1gCH CH N N O CH.sub.3 OCH.sub.3 H L-1hCH CH N N O CH.sub.3 OCH.sub.3 H L-1iCH CH N N O CH.sub.3 OCH.sub.3 H L-1jCH CH N N O CH.sub.3 OCH.sub.3 H L-1kCH CH N N O CH.sub.3 OCH.sub.3 H L-3aCH CH N N O CH.sub.3 OCH.sub.3 H L-3bCH CH N N O CH.sub.3 OCH.sub.3 H L-4aCH CH N N O CH.sub.3 OCH.sub.3 H L-7aCH CH N N O CH.sub.3 OCH.sub.3 H L-8aCH CH N N O CH.sub.3 OCH.sub.3 H L-8bCH CH N N O CH.sub.3 OCH.sub.3 H L-9aCH CH N N O CH.sub.3 OCH.sub.3 H L-12bCH CH N N O CH.sub.3 OCH.sub.3 H L-14aCH CH N N O CH.sub.3 OCH.sub.3 H L-15aCH CH N N O CH.sub.3 OCH.sub.3 H L-16aCH CH N N O CH.sub.3 OCH.sub.3 H L-16bCH CH N N O CH.sub.3 OCH.sub.3 H L-18aCH CH N N O CH.sub.3 OCH.sub.3 H L-20aCH CH N N O CH.sub.3 OCH.sub.3 H L-22aCH CH N N S CH.sub.3 OCH.sub.3 H L-1aCH CH N N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH N N O OCH.sub.3 OCH.sub.3 H L-1aCH CH N N O OCH.sub.3 OCH.sub.3 H L-1bCH CH N N O OCH.sub.3 OCH.sub.3 H L-1cCH CH N N O OCH.sub.3 OCH.sub.3 H L-1dCH CH N N O OCH.sub.3 OCH.sub.3 H L-1eCH CH N N O OCH.sub.3 OCH.sub.3 H L-1fCH CH N N O OCH.sub.3 OCH.sub.3 H L-1gCH CH N N O OCH.sub.3 OCH.sub.3 H L-1hCH CH N N O OCH.sub.3 OCH.sub.3 H L-1iCH CH N N O OCH.sub.3 OCH.sub.3 H L-1jCH CH N N O OCH.sub.3 OCH.sub.3 H L-1kCH CH N N O OCH.sub.3 OCH.sub.3 H L-3aCH CH N N O OCH.sub.3 OCH.sub.3 H L-3bCH CH N N O OCH.sub.3 OCH.sub.3 H L-4aCH CH N N O OCH.sub.3 OCH.sub.3 H L-7aCH CH N N O OCH.sub.3 OCH.sub.3 H L-8aCH CH N N O OCH.sub.3 OCH.sub.3 H L-8bCH CH N N O OCH.sub.3 OCH.sub.3 H L-9aCH CH N N O OCH.sub.3 OCH.sub.3 H L-12aCH CH N N O OCH.sub.3 OCH.sub.3 H L-12bCH CH N N O OCH.sub.3 OCH.sub.3 H L-14aCH CH N N O OCH.sub.3 OCH.sub.3 H L-15aCH CH N N O OCH.sub.3 OCH.sub.3 H L-16aCH CH N N O OCH.sub.3 OCH.sub.3 H L-16bCH CH N N O OCH.sub.3 OCH.sub.3 H L-18aCH CH N N O OCH.sub.3 OCH.sub.3 H L-20aCH CH N N O OCH.sub.3 OCH.sub.3 H L-22aCH CH N N S OCH.sub.3 OCH.sub.3 H L-1aCH CH N N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH N O CH.sub.3 CH.sub.3 H L-1aCH CH CH N O CH.sub.3 CH.sub.3 H L-1bCH CH CH N O CH.sub.3 CH.sub.3 H L-1cCH CH CH N O CH.sub.3 CH.sub.3 H L-1dCH CH CH N O CH.sub.3 CH.sub.3 H L-1eCH CH CH N O CH.sub.3 CH.sub.3 H L-1fCH CH CH N O CH.sub.3 CH.sub.3 H L-1gCH CH CH N O CH.sub.3 CH.sub.3 H L-1hCH CH CH N O CH.sub.3 CH.sub.3 H L-1iCH CH CH N O CH.sub.3 CH.sub.3 H L-1jCH CH CH N O CH.sub.3 CH.sub.3 H L-1kCH CH CH N O CH.sub.3 CH.sub.3 H L-3aCH CH CH N O CH.sub.3 CH.sub.3 H L-3bCH CH CH N O CH.sub.3 CH.sub.3 H L-4aCH CH CH N O CH.sub.3 CH.sub.3 H L-7aCH CH CH N O CH.sub.3 CH.sub.3 H L-8aCH CH CH N O CH.sub.3 CH.sub.3 H L-8bCH CH CH N O CH.sub.3 CH.sub.3 H L-9aCH CH CH N O CH.sub.3 CH.sub.3 H L-12aCH CH CH N O CH.sub.3 CH.sub.3 H L-12bCH CH CH N O CH.sub.3 CH.sub.3 H L-14aCH CH CH N O CH.sub.3 CH.sub.3 H L-15aCH CH CH N O CH.sub.3 CH.sub.3 H L-16aCH CH CH N O CH.sub.3 CH.sub.3 H L-16bCH CH CH N O CH.sub.3 CH.sub.3 H L-18aCH CH CH N O CH.sub.3 CH.sub.3 H L-20aCH CH CH N O CH.sub.3 CH.sub.3 H L-22aCH CH CH N S CH.sub.3 CH.sub.3 H L-1aCH CH CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH N O OCH.sub.3 CH.sub.3 H L-1aCH CH CH N O OCH.sub.3 CH.sub.3 H L-1bCH CH CH N O OCH.sub.3 CH.sub.3 H L-1cCH CH CH N O OCH.sub.3 CH.sub.3 H L-1dCH CH CH N O OCH.sub.3 CH.sub.3 H L-1eCH CH CH N O OCH.sub.3 CH.sub.3 H L-1fCH CH CH N O OCH.sub.3 CH.sub.3 H L-1gCH CH CH N O OCH.sub.3 CH.sub. 3 H L-1hCH CH CH N O OCH.sub.3 CH.sub.3 H L-1iCH CH CH N O OCH.sub.3 CH.sub.3 H L-1jCH CH CH N O OCH.sub.3 CH.sub.3 H L-1kCH CH CH N O OCH.sub.3 CH.sub.3 H L-3aCH CH CH N O OCH.sub.3 CH.sub.3 H L-3bCH CH CH N O OCH.sub.3 CH.sub.3 H L-4aCH CH CH N O OCH.sub.3 CH.sub.3 H L-7aCH CH CH N O OCH.sub.3 CH.sub.3 H L-8aCH CH CH N O OCH.sub.3 CH.sub.3 H L-8bCH CH CH N O OCH.sub.3 CH.sub.3 H L-9aCH CH CH N O OCH.sub.3 CH.sub.3 H L-12bCH CH CH N O OCH.sub.3 CH.sub.3 H L-14aCH CH CH N O OCH.sub.3 CH.sub.3 H L-15aCH CH CH N O OCH.sub.3 CH.sub.3 H L-16aCH CH CH N O OCH.sub.3 CH.sub.3 H L-16bCH CH CH N O OCH.sub.3 CH.sub.3 H L-18aCH CH CH N O OCH.sub.3 CH.sub.3 H L-20aCH CH CH N O OCH.sub.3 CH.sub.3 H L-22aCH CH CH N S OCH.sub.3 CH.sub.3 H L-1aCH CH CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH CH N O CH.sub.3 OCH.sub.3 H L-1aCH CH CH N O CH.sub.3 OCH.sub.3 H L-1bCH CH CH N O CH.sub.3 OCH.sub.3 H L-1cCH CH CH N O CH.sub.3 OCH.sub.3 H L-1dCH CH CH N O CH.sub.3 OCH.sub.3 H L-1eCH CH CH N O CH.sub.3 OCH.sub.3 H L-1fCH CH CH N O CH.sub.3 OCH.sub.3 H L-1gCH CH CH N O CH.sub.3 OCH.sub.3 H L-1hCH CH CH N O CH.sub.3 OCH.sub.3 H L-1iCH CH CH N O CH.sub.3 OCH.sub.3 H L-1jCH CH CH N O CH.sub.3 OCH.sub.3 H L-1kCH CH CH N O CH.sub.3 OCH.sub.3 H L-3aCH CH CH N O CH.sub.3 OCH.sub.3 H L-3bCH CH CH N O CH.sub.3 OCH.sub.3 H L-4aCH CH CH N O CH.sub.3 OCH.sub.3 H L-7aCH CH CH N O CH.sub.3 OCH.sub.3 H L-8aCH CH CH N O CH.sub.3 OCH.sub.3 H L-8bCH CH CH N O CH.sub.3 OCH.sub.3 H L-9aCH CH CH N O CH.sub.3 OCH.sub.3 H L-12bCH CH CH N O CH.sub.3 OCH.sub.3 H L-14aCH CH CH N O CH.sub.3 OCH.sub.3 H L-15aCH CH CH N O CH.sub.3 OCH.sub.3 H L-16aCH CH CH N O CH.sub.3 OCH.sub.3 H L-16bCH CH CH N O CH.sub.3 OCH.sub.3 H L-18aCH CH CH N O CH.sub.3 OCH.sub.3 H L-20aCH CH CH N O CH.sub.3 OCH.sub.3 H L-22aCH CH CH N S CH.sub.3 OCH.sub.3 H L-1aCH CH CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1bCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1cCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1dCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1eCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1fCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1gCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1hCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1iCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1jCH CH CH N O OCH.sub.3 OCH.sub.3 H L-1kCH CH CH N O OCH.sub.3 OCH.sub.3 H L-3aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-3bCH CH CH N O OCH.sub.3 OCH.sub.3 H L-4aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-7aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-8aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-8bCH CH CH N O OCH.sub.3 OCH.sub.3 H L-9aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-12bCH CH CH N O OCH.sub.3 OCH.sub.3 H L-14aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-15aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-16aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-16bCH CH CH N O OCH.sub.3 OCH.sub.3 H L-18aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-20aCH CH CH N O OCH.sub.3 OCH.sub.3 H L-22aCH CH CH N S OCH.sub.3 OCH.sub.3 H L-1aCH CH CH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH N O CH.sub.3 CH.sub.3 H L-1aN N CH N O CH.sub.3 CH.sub.3 H L-1bN N CH N O CH.sub.3 CH.sub.3 H L-1cN N CH N O CH.sub.3 CH.sub.3 H L-1dN N CH N O CH.sub.3 CH.sub.3 H L-1eN N CH N O CH.sub.3 CH.sub.3 H L-1fN N CH N O CH.sub.3 CH.sub.3 H L-1gN N CH N O CH.sub.3 CH.sub.3 H L-1hN N CH N O CH.sub.3 CH.sub.3 H L-1iN N CH N O CH.sub.3 CH.sub.3 H L-1jN N CH N O CH.sub.3 CH.sub.3 H L-1kN N CH N O CH.sub.3 CH.sub.3 H L-3aN N CH N O CH.sub.3 CH.sub.3 H L-3bN N CH N O CH.sub.3 CH.sub.3 H L-4aN N CH N O CH.sub.3 CH.sub.3 H L-7aN N CH N O CH.sub.3 CH.sub.3 H L-8aN N CH N O CH.sub.3 CH.sub.3 H L-8bN N CH N O CH.sub.3 CH.sub.3 H L-9aN N CH N O CH.sub.3 CH.sub.3 H L-12aN N CH N O CH.sub.3 CH.sub.3 H L-12bN N CH N O CH.sub.3 CH.sub.3 H L-14aN N CH N O CH.sub.3 CH.sub.3 H L-15aN N CH N O CH.sub.3 CH.sub.3 H L-16aN N CH N O CH.sub.3 CH.sub.3 H L-16bN N CH N O CH.sub.3 CH.sub.3 H L-18aN N CH N O CH.sub.3 CH.sub.3 H L-20aN N CH N O CH.sub.3 CH.sub.3 H L-22aN N CH N S CH.sub.3 CH.sub.3 H L-1aN N CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH N O OCH.sub.3 CH.sub.3 H L-1aN N CH N O OCH.sub.3 CH.sub.3 H L-1bN N CH N O OCH.sub.3 CH.sub.3 H L-1cN N CH N O OCH.sub.3 CH.sub.3 H L-1dN N CH N O OCH.sub.3 CH.sub.3 H L-1eN N CH N O OCH.sub.3 CH.sub.3 H L-1fN N CH N O OCH.sub.3 CH.sub.3 H L-1gN N CH N O OCH.sub.3 CH.sub.3 H L-1hN N CH N O OCH.sub.3 CH.sub.3 H L-1iN N CH N O OCH.sub.3 CH.sub.3 H L-1jN N CH N O OCH.sub.3 CH.sub.3 H L-1kN N CH N O OCH.sub.3 CH.sub.3 H L-3aN N CH N O OCH.sub.3 CH.sub.3 H L-3bN N CH N O OCH.sub.3 CH.sub.3 H L-4aN N CH N O OCH.sub.3 CH.sub.3 H L-7aN N CH N O OCH.sub.3 CH.sub.3 H L-8aN N CH N O OCH.sub.3 CH.sub.3 H L-8bN N CH N O OCH.sub.3 CH.sub.3 H L-9aN N CH N O OCH.sub.3 CH.sub.3 H L-12aN N CH N O OCH.sub.3 CH.sub.3 H L-12bN N CH N O OCH.sub.3 CH.sub.3 H L-14aN N CH N O OCH.sub. 3 CH.sub.3 H L-15aN N CH N O OCH.sub.3 CH.sub.3 H L-16aN N CH N O OCH.sub.3 CH.sub.3 H L-16bN N CH N O OCH.sub.3 CH.sub.3 H L-18aN N CH N O OCH.sub.3 CH.sub.3 H L-20aN N CH N O OCH.sub.3 CH.sub.3 H L-22aN N CH N S OCH.sub.3 CH.sub.3 H L-1aN N CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N CH N O CH.sub.3 OCH.sub.3 H L-1aN N CH N O CH.sub.3 OCH.sub.3 H L-1bN N CH N O CH.sub.3 OCH.sub.3 H L-1cN N CH N O CH.sub.3 OCH.sub.3 H L-1dN N CH N O CH.sub.3 OCH.sub.3 H L-1eN N CH N O CH.sub.3 OCH.sub.3 H L-1fN N CH N O CH.sub.3 OCH.sub.3 H L-1gN N CH N O CH.sub.3 OCH.sub.3 H L-1hN N CH N O CH.sub.3 OCH.sub.3 H L-1iN N CH N O CH.sub.3 OCH.sub.3 H L-1jN N CH N O CH.sub.3 OCH.sub.3 H L-1kN N CH N O CH.sub.3 OCH.sub.3 H L-3aN N CH N O CH.sub.3 OCH.sub.3 H L-3bN N CH N O CH.sub.3 OCH.sub.3 H L-4aN N CH N O CH.sub.3 OCH.sub.3 H L-7aN N CH N O CH.sub.3 OCH.sub.3 H L-8aN N CH N O CH.sub.3 OCH.sub.3 H L-8bN N CH N O CH.sub.3 OCH.sub.3 H L-9aN N CH N O CH.sub.3 OCH.sub.3 H L-12aN N CH N O CH.sub.3 OCH.sub.3 H L-12bN N CH N O CH.sub.3 OCH.sub.3 H L-14aN N CH N O CH.sub.3 OCH.sub.3 H L-15aN N CH N O CH.sub.3 OCH.sub.3 H L-16aN N CH N O CH.sub.3 OCH.sub.3 H L-16bN N CH N O CH.sub.3 OCH.sub.3 H L-18aN N CH N O CH.sub.3 OCH.sub.3 H L-20aN N CH N O CH.sub.3 OCH.sub.3 H L-22aN N CH N S CH.sub.3 OCH.sub.3 H L-1aN N CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N CH N O OCH.sub.3 OCH.sub.3 H L-1aN N CH N O OCH.sub.3 OCH.sub.3 H L-1bN N CH N O OCH.sub.3 OCH.sub.3 H L-1cN N CH N O OCH.sub.3 OCH.sub.3 H L-1dN N CH N O OCH.sub.3 OCH.sub.3 H L-1eN N CH N O OCH.sub.3 OCH.sub.3 H L-1fN N CH N O OCH.sub.3 OCH.sub.3 H L-1gN N CH N O OCH.sub.3 OCH.sub.3 H L-1hN N CH N O OCH.sub.3 OCH.sub.3 H L-1iN N CH N O OCH.sub.3 OCH.sub.3 H L-1jN N CH N O OCH.sub.3 OCH.sub.3 H L-1kN N CH N O OCH.sub.3 OCH.sub.3 H L-3aN N CH N O OCH.sub.3 OCH.sub.3 H L-3bN N CH N O OCH.sub.3 OCH.sub.3 H L-4aN N CH N O OCH.sub.3 OCH.sub.3 H L-7aN N CH N O OCH.sub.3 OCH.sub.3 H L-8aN N CH N O OCH.sub.3 OCH.sub.3 H L-8bN N CH N O OCH.sub.3 OCH.sub.3 H L-9aN N CH N O OCH.sub.3 OCH.sub.3 H L-12aN N CH N O OCH.sub.3 OCH.sub.3 H L-12bN N CH N O OCH.sub.3 OCH.sub.3 H L-14aN N CH N O OCH.sub.3 OCH.sub.3 H L-15aN N CH N O OCH.sub.3 OCH.sub.3 H L-16aN N CH N O OCH.sub.3 OCH.sub.3 H L-16bN N CH N O OCH.sub.3 OCH.sub.3 H L-18aN N CH N O OCH.sub.3 OCH.sub.3 H L-20aN N CH N O OCH.sub.3 OCH.sub.3 H L-22aN N CH N S OCH.sub.3 OCH.sub.3 H L-1aN N CH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N N O CH.sub.3 CH.sub.3 H L-1aN CH N N O CH.sub.3 CH.sub.3 H L-1bN CH N N O CH.sub.3 CH.sub.3 H L-1cN CH N N O CH.sub.3 CH.sub.3 H L-1dN CH N N O CH.sub.3 CH.sub.3 H L-1eN CH N N O CH.sub.3 CH.sub.3 H L-1fN CH N N O CH.sub.3 CH.sub.3 H L-1gN CH N N O CH.sub.3 CH.sub.3 H L-1hN CH N N O CH.sub.3 CH.sub.3 H L-1iN CH N N O CH.sub.3 CH.sub.3 H L-1jN CH N N O CH.sub.3 CH.sub.3 H L-1kN CH N N O CH.sub.3 CH.sub.3 H L-3aN CH N N O CH.sub.3 CH.sub.3 H L-3bN CH N N O CH.sub.3 CH.sub.3 H L-4aN CH N N O CH.sub.3 CH.sub.3 H L-7aN CH N N O CH.sub.3 CH.sub.3 H L-8aN CH N N O CH.sub.3 CH.sub.3 H L-8bN CH N N O CH.sub.3 CH.sub.3 H L-9aN CH N N O CH.sub.3 CH.sub.3 H L-12aN CH N N O CH.sub.3 CH.sub.3 H L-12bN CH N N O CH.sub.3 CH.sub.3 H L-14aN CH N N O CH.sub.3 CH.sub.3 H L-15aN CH N N O CH.sub.3 CH.sub.3 H L-16aN CH N N O CH.sub.3 CH.sub.3 H L-16bN CH N N O CH.sub.3 CH.sub.3 H L-18aN CH N N O CH.sub.3 CH.sub.3 H L-20aN CH N N O CH.sub.3 CH.sub.3 H L-22aN CH N N S CH.sub.3 CH.sub.3 H L-1aN CH N N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N N O OCH.sub.3 CH.sub.3 H L-1aN CH N N O OCH.sub.3 CH.sub.3 H L-1bN CH N N O OCH.sub.3 CH.sub.3 H L-1cN CH N N O OCH.sub.3 CH.sub.3 H L-1dN CH N N O OCH.sub.3 CH.sub.3 H L-1eN CH N N O OCH.sub.3 CH.sub.3 H L-1fN CH N N O OCH.sub.3 CH.sub.3 H L-1gN CH N N O OCH.sub.3 CH.sub.3 H L-1hN CH N N O OCH.sub.3 CH.sub.3 H L-1iN CH N N O OCH.sub.3 CH.sub.3 H L-1jN CH N N O OCH.sub.3 CH.sub.3 H L-1kN CH N N O OCH.sub.3 CH.sub.3 H L-3aN CH N N O OCH.sub.3 CH.sub.3 H L-3bN CH N N O OCH.sub.3 CH.sub.3 H L-4aN CH N N O OCH.sub.3 CH.sub.3 H L-7aN CH N N O OCH.sub.3 CH.sub.3 H L-8aN CH N N O OCH.sub.3 CH.sub.3 H L-8bN CH N N O OCH.sub.3 CH.sub.3 H L-9aN CH N N O OCH.sub.3 CH.sub.3 H L-12aN CH N N O OCH.sub.3 CH.sub.3 H L-12bN CH N N O OCH.sub.3 CH.sub.3 H L-14aN CH N N O OCH.sub.3 CH.sub.3 H L-15aN CH N N O OCH.sub.3 CH.sub.3 H L-16aN CH N N O OCH.sub.3 CH.sub.3 H L-16bN CH N N O OCH.sub.3 CH.sub.3 H L-18aN CH N N O OCH.sub.3 CH.sub.3 H L-20aN CH N N O OCH.sub.3 CH.sub.3 H L-22aN CH N N S OCH.sub.3 CH.sub.3 H L-1aN CH N N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH N N O CH.sub.3 OCH.sub.3 H L-1aN CH N N O CH.sub.3 OCH.sub.3 H L-1bN CH N N O CH.sub.3 OCH.sub.3 H L-1cN CH N N O CH.sub.3 OCH.sub.3 H L-1dN CH N N O CH.sub.3 OCH.sub.3 H L-1eN CH N N O CH.sub.3 OCH.sub.3 H L-1fN CH N N O CH.sub.3 OCH.sub.3 H L-1gN CH N N O CH.sub.3 OCH.sub.3 H L-1hN CH N N O CH.sub.3 OCH.sub.3 H L-1iN CH N N O CH.sub.3 OCH.sub.3 H L-1jN CH N N O CH.sub.3 OCH.sub.3 H L-1kN CH N N O CH.sub.3 OCH.sub.3 H L-3aN CH N N O CH.sub.3 OCH.sub.3 H L-3bN CH N N O CH.sub.3 OCH.sub.3 H L-4aN CH N N O CH.sub.3 OCH.sub.3 H L-7aN CH N N O CH.sub.3 OCH.sub.3 H L-8aN CH N N O CH.sub.3 OCH.sub.3 H L-8bN CH N N O CH.sub.3 OCH.sub.3 H L-9aN CH N N O CH.sub.3 OCH.sub.3 H L-12aN CH N N O CH.sub.3 OCH.sub.3 H L-12bN CH N N O CH.sub.3 OCH.sub.3 H L-14aN CH N N O CH.sub. 3 OCH.sub.3 H L-15aN CH N N O CH.sub.3 OCH.sub.3 H L-16aN CH N N O CH.sub.3 OCH.sub.3 H L-16bN CH N N O CH.sub.3 OCH.sub.3 H L-18aN CH N N O CH.sub.3 OCH.sub.3 H L-20aN CH N N O CH.sub.3 OCH.sub.3 H L-22aN CH N N S CH.sub.3 OCH.sub.3 H L-1aN CH N N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH N N O OCH.sub.3 OCH.sub.3 H L-1aN CH N N O OCH.sub.3 OCH.sub.3 H L-1bN CH N N O OCH.sub.3 OCH.sub.3 H L-1cN CH N N O OCH.sub.3 OCH.sub.3 H L-1dN CH N N O OCH.sub.3 OCH.sub.3 H L-1eN CH N N O OCH.sub.3 OCH.sub.3 H L-1fN CH N N O OCH.sub.3 OCH.sub.3 H L-1gN CH N N O OCH.sub.3 OCH.sub.3 H L-1hN CH N N O OCH.sub.3 OCH.sub.3 H L-1iN CH N N O OCH.sub.3 OCH.sub.3 H L-1jN CH N N O OCH.sub.3 OCH.sub.3 H L-1kN CH N N O OCH.sub.3 OCH.sub.3 H L-3aN CH N N O OCH.sub.3 OCH.sub.3 H L-3bN CH N N O OCH.sub.3 OCH.sub.3 H L-4aN CH N N O OCH.sub.3 OCH.sub.3 H L-7aN CH N N O OCH.sub.3 OCH.sub.3 H L-8aN CH N N O OCH.sub.3 OCH.sub.3 H L-8bN CH N N O OCH.sub.3 OCH.sub.3 H L-9aN CH N N O OCH.sub.3 OCH.sub.3 H L-12aN CH N N O OCH.sub.3 OCH.sub.3 H L-12bN CH N N O OCH.sub.3 OCH.sub.3 H L-14aN CH N N O OCH.sub.3 OCH.sub.3 H L-15aN CH N N O OCH.sub.3 OCH.sub.3 H L-16aN CH N N O OCH.sub.3 OCH.sub.3 H L-16bN CH N N O OCH.sub.3 OCH.sub.3 H L-18aN CH N N O OCH.sub.3 OCH.sub.3 H L-20aN CH N N O OCH.sub.3 OCH.sub.3 H L-22aN CH N N S OCH.sub.3 OCH.sub.3 H L-1aN CH N N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH N O CH.sub.3 CH.sub.3 H L-1aN CH CH N O CH.sub.3 CH.sub.3 H L-1bN CH CH N O CH.sub.3 CH.sub.3 H L-1cN CH CH N O CH.sub.3 CH.sub.3 H L-1dN CH CH N O CH.sub.3 CH.sub.3 H L-1eN CH CH N O CH.sub.3 CH.sub.3 H L-1fN CH CH N O CH.sub.3 CH.sub.3 H L-1gN CH CH N O CH.sub.3 CH.sub.3 H L-1hN CH CH N O CH.sub.3 CH.sub.3 H L-1iN CH CH N O CH.sub.3 CH.sub.3 H L-1jN CH CH N O CH.sub.3 CH.sub.3 H L-1kN CH CH N O CH.sub.3 CH.sub.3 H L-3aN CH CH N O CH.sub.3 CH.sub.3 H L-3bN CH CH N O CH.sub.3 CH.sub.3 H L-4aN CH CH N O CH.sub.3 CH.sub.3 H L-7aN CH CH N O CH.sub.3 CH.sub.3 H L-8aN CH CH N O CH.sub.3 CH.sub.3 H L-8bN CH CH N O CH.sub.3 CH.sub.3 H L-9aN CH CH N O CH.sub.3 CH.sub.3 H L-12aN CH CH N O CH.sub.3 CH.sub.3 H L-12bN CH CH N O CH.sub.3 CH.sub.3 H L-14aN CH CH N O CH.sub.3 CH.sub.3 H L-15aN CH CH N O CH.sub.3 CH.sub.3 H L-16aN CH CH N O CH.sub.3 CH.sub.3 H L-16bN CH CH N O CH.sub.3 CH.sub.3 H L-18aN CH CH N O CH.sub.3 CH.sub.3 H L-20aN CH CH N O CH.sub.3 CH.sub.3 H L-22aN CH CH N S CH.sub.3 CH.sub.3 H L-1aN CH CH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH N O OCH.sub.3 CH.sub.3 H L-1aN CH CH N O OCH.sub.3 CH.sub.3 H L-1bN CH CH N O OCH.sub.3 CH.sub.3 H L-1cN CH CH N O OCH.sub.3 CH.sub.3 H L-1dN CH CH N O OCH.sub.3 CH.sub.3 H L-1eN CH CH N O OCH.sub.3 CH.sub.3 H L-1fN CH CH N O OCH.sub.3 CH.sub.3 H L-1gN CH CH N O OCH.sub.3 CH.sub.3 H L-1hN CH CH N O OCH.sub.3 CH.sub.3 H L-1iN CH CH N O OCH.sub.3 CH.sub.3 H L-1jN CH CH N O OCH.sub.3 CH.sub.3 H L-1kN CH CH N O OCH.sub.3 CH.sub.3 H L-3aN CH CH N O OCH.sub.3 CH.sub.3 H L-3bN CH CH N O OCH.sub.3 CH.sub.3 H L-4aN CH CH N O OCH.sub.3 CH.sub.3 H L-7aN CH CH N O OCH.sub.3 CH.sub.3 H L-8aN CH CH N O OCH.sub.3 CH.sub.3 H L-8bN CH CH N O OCH.sub.3 CH.sub.3 H L-9aN CH CH N O OCH.sub.3 CH.sub.3 H L-12aN CH CH N O OCH.sub.3 CH.sub.3 H L-12bN CH CH N O OCH.sub.3 CH.sub.3 H L-14aN CH CH N O OCH.sub.3 CH.sub.3 H L-15aN CH CH N O OCH.sub.3 CH.sub.3 H L-16aN CH CH N O OCH.sub.3 CH.sub.3 H L-16bN CH CH N O OCH.sub.3 CH.sub.3 H L-18aN CH CH N O OCH.sub.3 CH.sub.3 H L-20aN CH CH N O OCH.sub.3 CH.sub.3 H L-22aN CH CH N S OCH.sub.3 CH.sub.3 H L-1aN CH CH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH CH N O CH.sub.3 OCH.sub.3 H L-1aN CH CH N O CH.sub.3 OCH.sub.3 H L-1bN CH CH N O CH.sub.3 OCH.sub.3 H L-1cN CH CH N O CH.sub.3 OCH.sub.3 H L-1dN CH CH N O CH.sub.3 OCH.sub.3 H L-1eN CH CH N O CH.sub.3 OCH.sub.3 H L-1fN CH CH N O CH.sub.3 OCH.sub.3 H L-1gN CH CH N O CH.sub.3 OCH.sub.3 H L-1hN CH CH N O CH.sub.3 OCH.sub.3 H L-1iN CH CH N O CH.sub.3 OCH.sub.3 H L-1jN CH CH N O CH.sub.3 OCH.sub.3 H L-1kN CH CH N O CH.sub.3 OCH.sub.3 H L-3aN CH CH N O CH.sub.3 OCH.sub.3 H L-3bN CH CH N O CH.sub.3 OCH.sub.3 H L-4aN CH CH N O CH.sub.3 OCH.sub.3 H L-7aN CH CH N O CH.sub.3 OCH.sub.3 H L-8aN CH CH N O CH.sub.3 OCH.sub.3 H L-8bN CH CH N O CH.sub.3 OCH.sub.3 H L-9aN CH CH N O CH.sub.3 OCH.sub.3 H L-12aN CH CH N O CH.sub.3 OCH.sub.3 H L-12bN CH CH N O CH.sub.3 OCH.sub.3 H L-14aN CH CH N O CH.sub.3 OCH.sub.3 H L-15aN CH CH N O CH.sub.3 OCH.sub.3 H L-16aN CH CH N O CH.sub.3 OCH.sub.3 H L-16bN CH CH N O CH.sub.3 OCH.sub.3 H L-18aN CH CH N O CH.sub.3 OCH.sub.3 H L-20aN CH CH N O CH.sub.3 OCH.sub.3 H L-22aN CH CH N S CH.sub.3 OCH.sub.3 H L-1aN CH CH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH CH N O OCH.sub.3 OCH.sub.3 H L-1aN CH CH N O OCH.sub.3 OCH.sub.3 H L-1bN CH CH N O OCH.sub.3 OCH.sub.3 H L-1cN CH CH N O OCH.sub.3 OCH.sub.3 H L-1dN CH CH N O OCH.sub.3 OCH.sub.3 H L-1eN CH CH N O OCH.sub.3 OCH.sub.3 H L-1fN CH CH N O OCH.sub.3 OCH.sub.3 H L-1gN CH CH N O OCH.sub.3 OCH.sub.3 H L-1hN CH CH N O OCH.sub.3 OCH.sub.3 H L-1iN CH CH N O OCH.sub.3 OCH.sub.3 H L-1jN CH CH N O OCH.sub.3 OCH.sub.3 H L-1kN CH CH N O OCH.sub.3 OCH.sub.3 H L-3aN CH CH N O OCH.sub.3 OCH.sub.3 H L-3bN CH CH N O OCH.sub.3 OCH.sub.3 H L-4aN CH CH N O OCH.sub.3 OCH.sub.3 H L-7aN CH CH N O OCH.sub.3 OCH.sub.3 H L-8aN CH CH N O OCH.sub.3 OCH.sub.3 H L-8bN CH CH N O OCH.sub.3 OCH.sub.3 H L-9aN CH CH N O OCH.sub.3 OCH.sub.3 H L-12aN CH CH N O OCH.sub.3 OCH.sub.3 H L-12bN CH CH N O OCH.sub.3 OCH.sub.3 H L-14aN CH CH N O OCH.sub. 3 OCH.sub.3 H L-15aN CH CH N O OCH.sub.3 OCH.sub.3 H L-16aN CH CH N O OCH.sub.3 OCH.sub.3 H L-16bN CH CH N O OCH.sub.3 OCH.sub.3 H L-18aN CH CH N O OCH.sub.3 OCH.sub.3 H L-20aN CH CH N O OCH.sub.3 OCH.sub.3 H L-22aN CH CH N S OCH.sub.3 OCH.sub.3 H L-1aN CH CH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1a__________________________________________________________________________
TABLE 6______________________________________General Formula 6 m.p.Z Z.sub.1 Z.sub.4 W X Y R L (.degree.C.)______________________________________CH CH S O CH.sub.3 CH.sub.3 H L-1aCH CH S O CH.sub.3 CH.sub.3 H L-1bCH CH S O CH.sub.3 CH.sub.3 H L-1cCH CH S O CH.sub.3 CH.sub.3 H L-1dCH CH S O CH.sub.3 CH.sub.3 H L-1eCH CH S O CH.sub.3 CH.sub.3 H L-1fCH CH S O CH.sub.3 CH.sub.3 H L-1gCH CH S O CH.sub.3 CH.sub.3 H L-1hCH CH S O CH.sub.3 CH.sub.3 H L-1iCH CH S O CH.sub.3 CH.sub.3 H L-1jCH CH S O CH.sub.3 CH.sub.3 H L-1kCH CH S O CH.sub.3 CH.sub.3 H L-3aCH CH S O CH.sub.3 CH.sub.3 H L-3bCH CH S O CH.sub.3 CH.sub.3 H L-4aCH CH S O CH.sub.3 CH.sub.3 H L-7aCH CH S O CH.sub.3 CH.sub.3 H L-8aCH CH S O CH.sub.3 CH.sub.3 H L-8bCH CH S O CH.sub.3 CH.sub.3 H L-9aCH CH S O CH.sub.3 CH.sub.3 H L-12aCH CH S O CH.sub.3 CH.sub.3 H L-12bCH CH S O CH.sub.3 CH.sub.3 H L-14aCH CH S O CH.sub.3 CH.sub.3 H L-15aCH CH S O CH.sub.3 CH.sub.3 H L-16aCH CH S O CH.sub.3 CH.sub.3 H L-16bCH CH S O CH.sub.3 CH.sub.3 H L-18aCH CH S O CH.sub.3 CH.sub.3 H L-20aCH CH S O CH.sub.3 CH.sub.3 H L-22aCH CH S S CH.sub.3 CH.sub.3 H L-1aCH CH S O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH S O OCH.sub.3 CH.sub.3 H L-1aCH CH S O OCH.sub.3 CH.sub.3 H L-1bCH CH S O OCH.sub.3 CH.sub.3 H L-1cCH CH S O OCH.sub.3 CH.sub.3 H L-1dCH CH S O OCH.sub.3 CH.sub.3 H L-1eCH CH S O OCH.sub.3 CH.sub.3 H L-1fCH CH S O OCH.sub.3 CH.sub.3 H L-1gCH CH S O OCH.sub.3 CH.sub.3 H L-1hCH CH S O OCH.sub.3 CH.sub.3 H L-1iCH CH S O OCH.sub.3 CH.sub.3 H L-1jCH CH S O OCH.sub.3 CH.sub.3 H L-1kCH CH S O OCH.sub.3 CH.sub.3 H L-3aCH CH S O OCH.sub.3 CH.sub.3 H L-3bCH CH S O OCH.sub.3 CH.sub.3 H L-4aCH CH S O OCH.sub.3 CH.sub.3 H L-7aCH CH S O OCH.sub.3 CH.sub.3 H L-8aCH CH S O OCH.sub.3 CH.sub.3 H L-8bCH CH S O OCH.sub.3 CH.sub.3 H L-9aCH CH S O OCH.sub.3 CH.sub.3 H L-12aCH CH S O OCH.sub.3 CH.sub.3 H L-12bCH CH S O OCH.sub.3 CH.sub.3 H L-14aCH CH S O OCH.sub.3 CH.sub.3 H L-15aCH CH S O OCH.sub.3 CH.sub.3 H L-16aCH CH S O OCH.sub.3 CH.sub.3 H L-16bCH CH S O OCH.sub.3 CH.sub.3 H L-18aCH CH S O OCH.sub.3 CH.sub.3 H L-20aCH CH S O OCH.sub.3 CH.sub.3 H L-22aCH CH S S OCH.sub.3 CH.sub.3 H L-1aCH CH S O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH S O CH.sub.3 OCH.sub.3 H L-1aCH CH S O CH.sub.3 OCH.sub.3 H L-1bCH CH S O CH.sub.3 OCH.sub.3 H L-1cCH CH S O CH.sub.3 OCH.sub.3 H L-1dCH CH S O CH.sub.3 OCH.sub.3 H L-1eCH CH S O CH.sub.3 OCH.sub.3 H L-1fCH CH S O CH.sub.3 OCH.sub.3 H L-1gCH CH S O CH.sub.3 OCH.sub.3 H L-1hCH CH S O CH.sub.3 OCH.sub.3 H L-1iCH CH S O CH.sub.3 OCH.sub.3 H L-1jCH CH S O CH.sub.3 OCH.sub.3 H L-1kCH CH S O CH.sub.3 OCH.sub.3 H L-3aCH CH S O CH.sub.3 OCH.sub.3 H L-3bCH CH S O CH.sub.3 OCH.sub.3 H L-4aCH CH S O CH.sub.3 OCH.sub.3 H L-7aCH CH S O CH.sub.3 OCH.sub.3 H L-8aCH CH S O CH.sub.3 OCH.sub.3 H L-8bCH CH S O CH.sub.3 OCH.sub.3 H L-9aCH CH S O CH.sub.3 OCH.sub.3 H L-12aCH CH S O CH.sub.3 OCH.sub.3 H L-12bCH CH S O CH.sub.3 OCH.sub.3 H L-14aCH CH S O CH.sub.3 OCH.sub.3 H L-15aCH CH S O CH.sub.3 OCH.sub.3 H L-16aCH CH S O CH.sub.3 OCH.sub.3 H L-16bCH CH S O CH.sub.3 OCH.sub.3 H L-18aCH CH S O CH.sub.3 OCH.sub.3 H L-20aCH CH S O CH.sub.3 OCH.sub.3 H L-22aCH CH S S CH.sub.3 OCH.sub.3 H L-1aCH CH S O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH S O OCH.sub.3 OCH.sub.3 H L-1aCH CH S O OCH.sub.3 OCH.sub.3 H L-1bCH CH S O OCH.sub.3 OCH.sub.3 H L-1cCH CH S O OCH.sub.3 OCH.sub.3 H L-1dCH CH S O OCH.sub.3 OCH.sub.3 H L-1eCH CH S O OCH.sub.3 OCH.sub.3 H L-1fCH CH S O OCH.sub.3 OCH.sub.3 H L-1gCH CH S O OCH.sub.3 OCH.sub. 3 H L-1hCH CH S O OCH.sub.3 OCH.sub.3 H L-1iCH CH S O OCH.sub.3 OCH.sub.3 H L-1jCH CH S O OCH.sub.3 OCH.sub.3 H L-1kCH CH S O OCH.sub.3 OCH.sub.3 H L-3aCH CH S O OCH.sub.3 OCH.sub.3 H L-3bCH CH S O OCH.sub.3 OCH.sub.3 H L-4aCH CH S O OCH.sub.3 OCH.sub.3 H L-7aCH CH S O OCH.sub.3 OCH.sub.3 H L-8aCH CH S O OCH.sub.3 OCH.sub.3 H L-8bCH CH S O OCH.sub.3 OCH.sub.3 H L-9aCH CH S O OCH.sub.3 OCH.sub.3 H L-12aCH CH S O OCH.sub.3 OCH.sub.3 H L-12bCH CH S O OCH.sub.3 OCH.sub.3 H L-14aCH CH S O OCH.sub.3 OCH.sub.3 H L-15aCH CH S O OCH.sub.3 OCH.sub.3 H L-16aCH CH S O OCH.sub.3 OCH.sub.3 H L-16bCH CH S O OCH.sub.3 OCH.sub.3 H L-18aCH CH S O OCH.sub.3 OCH.sub.3 H L-20aCH CH S O OCH.sub.3 OCH.sub.3 H L-22aCH CH S S OCH.sub.3 OCH.sub. 3 H L-1aCH CH S O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH O O CH.sub.3 CH.sub.3 H L-1aCH CH O O CH.sub.3 CH.sub.3 H L-1bCH CH O O CH.sub.3 CH.sub.3 H L-1cCH CH O O CH.sub.3 CH.sub.3 H L-1dCH CH O O CH.sub.3 CH.sub.3 H L-1eCH CH O O CH.sub.3 CH.sub.3 H L-1fCH CH O O CH.sub.3 CH.sub.3 H L-1gCH CH O O CH.sub.3 CH.sub.3 H L-1hCH CH O O CH.sub.3 CH.sub.3 H L-1iCH CH O O CH.sub.3 CH.sub.3 H L-1jCH CH O O CH.sub.3 CH.sub.3 H L-1kCH CH O O CH.sub.3 CH.sub.3 H L-3aCH CH O O CH.sub.3 CH.sub.3 H L-3bCH CH O O CH.sub.3 CH.sub.3 H L-4aCH CH O O CH.sub.3 CH.sub.3 H L-7aCH CH O O CH.sub.3 CH.sub.3 H L-8aCH CH O O CH.sub.3 CH.sub.3 H L-8bCH CH O O CH.sub.3 CH.sub.3 H L-9aCH CH O O CH.sub.3 CH.sub.3 H L-12aCH CH O O CH.sub.3 CH.sub.3 H L-12bCH CH O O CH.sub.3 CH.sub.3 H L-14aCH CH O O CH.sub.3 CH.sub.3 H L-15aCH CH O O CH.sub.3 CH.sub.3 H L-16aCH CH O O CH.sub.3 CH.sub.3 H L-16bCH CH O O CH.sub.3 CH.sub.3 H L-18aCH CH O O CH.sub.3 CH.sub.3 H L-20aCH CH O O CH.sub.3 CH.sub.3 H L-22aCH CH O S CH.sub.3 CH.sub.3 H L-1aCH CH O O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH O O OCH.sub.3 CH.sub.3 H L-1aCH CH O O OCH.sub.3 CH.sub.3 H L-1bCH CH O O OCH.sub.3 CH.sub.3 H L-1cCH CH O O OCH.sub.3 CH.sub.3 H L-1dCH CH O O OCH.sub.3 CH.sub.3 H L-1eCH CH O O OCH.sub.3 CH.sub.3 H L-1fCH CH O O OCH.sub.3 CH.sub.3 H L-1gCH CH O O OCH.sub.3 CH.sub.3 H L-1hCH CH O O OCH.sub.3 CH.sub.3 H L-1iCH CH O O OCH.sub. 3 CH.sub.3 H L-1jCH CH O O OCH.sub.3 CH.sub.3 H L-1kCH CH O O OCH.sub.3 CH.sub.3 H L-3aCH CH O O OCH.sub.3 CH.sub.3 H L-3bCH CH O O OCH.sub.3 CH.sub.3 H L-4aCH CH O O OCH.sub.3 CH.sub.3 H L-7aCH CH O O OCH.sub.3 CH.sub.3 H L-8aCH CH O O OCH.sub.3 CH.sub.3 H L-8bCH CH O O OCH.sub.3 CH.sub.3 H L-9aCH CH O O OCH.sub.3 CH.sub.3 H L-12aCH CH O O OCH.sub.3 CH.sub.3 H L-12bCH CH O O OCH.sub.3 CH.sub.3 H L-14aCH CH O O OCH.sub.3 CH.sub.3 H L-15aCH CH O O OCH.sub.3 CH.sub.3 H L-16aCH CH O O OCH.sub.3 CH.sub.3 H L-16bCH CH O O OCH.sub.3 CH.sub.3 H L-18aCH CH O O OCH.sub.3 CH.sub.3 H L-20aCH CH O O OCH.sub.3 CH.sub.3 H L-22aCH CH O S OCH.sub.3 CH.sub.3 H L-1aCH CH O O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH O O CH.sub.3 OCH.sub.3 H L-1aCH CH O O CH.sub.3 OCH.sub.3 H L-1bCH CH O O CH.sub.3 OCH.sub.3 H L-1cCH CH O O CH.sub.3 OCH.sub.3 H L-1dCH CH O O CH.sub.3 OCH.sub.3 H L-1eCH CH O O CH.sub.3 OCH.sub.3 H L-1fCH CH O O CH.sub.3 OCH.sub.3 H L-1gCH CH O O CH.sub.3 OCH.sub.3 H L-1hCH CH O O CH.sub.3 OCH.sub.3 H L-1iCH CH O O CH.sub.3 OCH.sub.3 H L-1jCH CH O O CH.sub.3 OCH.sub.3 H L-1kCH CH O O CH.sub.3 OCH.sub.3 H L-3aCH CH O O CH.sub.3 OCH.sub.3 H L-3bCH CH O O CH.sub.3 OCH.sub.3 H L-4aCH CH O O CH.sub.3 OCH.sub.3 H L-7aCH CH O O CH.sub.3 OCH.sub.3 H L-8aCH CH O O CH.sub.3 OCH.sub.3 H L-8bCH CH O O CH.sub.3 OCH.sub.3 H L-9aCH CH O O CH.sub.3 OCH.sub.3 H L-12aCH CH O O CH.sub.3 OCH.sub.3 H L-12bCH CH O O CH.sub.3 OCH.sub.3 H L-14aCH CH O O CH.sub.3 OCH.sub.3 H L-15aCH CH O O CH.sub.3 OCH.sub.3 H L-16aCH CH O O CH.sub.3 OCH.sub.3 H L-16bCH CH O O CH.sub.3 OCH.sub.3 H L-18aCH CH O O CH.sub.3 OCH.sub.3 H L-20aCH CH O O CH.sub.3 OCH.sub.3 H L-22aCH CH O S CH.sub.3 OCH.sub.3 H L-1aCH CH O O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH O O OCH.sub.3 OCH.sub.3 H L-1aCH CH O O OCH.sub.3 OCH.sub.3 H L-1bCH CH O O OCH.sub.3 OCH.sub.3 H L-1cCH CH O O OCH.sub.3 OCH.sub.3 H L-1dCH CH O O OCH.sub.3 OCH.sub.3 H L-1eCH CH O O OCH.sub.3 OCH.sub.3 H L-1fCH CH O O OCH.sub.3 OCH.sub.3 H L-1gCH CH O O OCH.sub.3 OCH.sub.3 H L-1hCH CH O O OCH.sub.3 OCH.sub.3 H L-1iCH CH O O OCH.sub.3 OCH.sub.3 H L-1jCH CH O O OCH.sub.3 OCH.sub.3 H L-1kCH CH O O OCH.sub.3 OCH.sub.3 H L-3aCH CH O O OCH.sub.3 OCH.sub.3 H L-3bCH CH O O OCH.sub.3 OCH.sub.3 H L-4aCH CH O O OCH.sub.3 OCH.sub.3 H L-7aCH CH O O OCH.sub.3 OCH.sub.3 H L-8aCH CH O O OCH.sub.3 OCH.sub.3 H L-8bCH CH O O OCH.sub.3 OCH.sub.3 H L-9aCH CH O O OCH.sub.3 OCH.sub.3 H L-12aCH CH O O OCH.sub.3 OCH.sub.3 H L-12bCH CH O O OCH.sub.3 OCH.sub.3 H L-14aCH CH O O OCH.sub.3 OCH.sub.3 H L-15aCH CH O O OCH.sub.3 OCH.sub.3 H L-16aCH CH O O OCH.sub.3 OCH.sub.3 H L-16bCH CH O O OCH.sub.3 OCH.sub.3 H L-18aCH CH O O OCH.sub.3 OCH.sub.3 H L-20aCH CH O O OCH.sub.3 OCH.sub.3 H L-22aCH CH O S OCH.sub.3 OCH.sub.3 H L-1aCH CH O O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH S O CH.sub.3 CH.sub.3 H L-1aN CH S O CH.sub.3 CH.sub.3 H L-1bN CH S O CH.sub.3 CH.sub.3 H L-1cN CH S O CH.sub.3 CH.sub.3 H L-1dN CH S O CH.sub.3 CH.sub.3 H L-1eN CH S O CH.sub.3 CH.sub.3 H L-1fN CH S O CH.sub.3 CH.sub.3 H L-1gN CH S O CH.sub.3 CH.sub.3 H L-1hN CH S O CH.sub.3 CH.sub.3 H L-1iN CH S O CH.sub.3 CH.sub.3 H L-1jN CH S O CH.sub.3 CH.sub.3 H L-1kN CH S O CH.sub.3 CH.sub.3 H L-3aN CH S O CH.sub.3 CH.sub.3 H L-3bN CH S O CH.sub.3 CH.sub.3 H L-4aN CH S O CH.sub.3 CH.sub.3 H L-7aN CH S O CH.sub.3 CH.sub.3 H L-8aN CH S O CH.sub.3 CH.sub.3 H L-8bN CH S O CH.sub.3 CH.sub.3 H L-9aN CH S O CH.sub.3 CH.sub.3 H L-12aN CH S O CH.sub.3 CH.sub.3 H L-12bN CH S O CH.sub.3 CH.sub.3 H L-14aN CH S O CH.sub.3 CH.sub.3 H L-15aN CH S O CH.sub.3 CH.sub.3 H L-16aN CH S O CH.sub.3 CH.sub.3 H L-16bN CH S O CH.sub.3 CH.sub.3 H L-18aN CH S O CH.sub.3 CH.sub.3 H L-20aN CH S O CH.sub.3 CH.sub.3 H L-22aN CH S S CH.sub.3 CH.sub.3 H L-1aN CH S O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH S O OCH.sub.3 CH.sub.3 H L-1aN CH S O OCH.sub.3 CH.sub.3 H L-1bN CH S O OCH.sub.3 CH.sub.3 H L-1cN CH S O OCH.sub.3 CH.sub.3 H L-1dN CH S O OCH.sub.3 CH.sub.3 H L-1eN CH S O OCH.sub.3 CH.sub.3 H L-1fN CH S O OCH.sub.3 CH.sub.3 H L-1gN CH S O OCH.sub.3 CH.sub.3 H L-1hN CH S O OCH.sub.3 CH.sub.3 H L-1iN CH S O OCH.sub.3 CH.sub.3 H L-1jN CH S O OCH.sub.3 CH.sub.3 H L-1kN CH S O OCH.sub.3 CH.sub.3 H L-3aN CH S O OCH.sub.3 CH.sub.3 H L-3bN CH S O OCH.sub.3 CH.sub.3 H L-4aN CH S O OCH.sub.3 CH.sub.3 H L-7aN CH S O OCH.sub.3 CH.sub.3 H L-8aN CH S O OCH.sub.3 CH.sub.3 H L-8bN CH S O OCH.sub.3 CH.sub.3 H L-9aN CH S O OCH.sub.3 CH.sub.3 H L-12aN CH S O OCH.sub.3 CH.sub.3 H L-12bN CH S O OCH.sub.3 CH.sub.3 H L-14aN CH S O OCH.sub.3 CH.sub.3 H L-15aN CH S O OCH.sub.3 CH.sub.3 H L-16aN CH S O OCH.sub.3 CH.sub.3 H L-16bN CH S O OCH.sub.3 CH.sub.3 H L-18aN CH S O OCH.sub.3 CH.sub.3 H L-20aN CH S O OCH.sub.3 CH.sub.3 H L-22aN CH S S OCH.sub.3 CH.sub.3 H L-1aN CH S O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH S O CH.sub.3 OCH.sub.3 H L-1aN CH S O CH.sub.3 OCH.sub.3 H L-1bN CH S O CH.sub.3 OCH.sub.3 H L-1cN CH S O CH.sub.3 OCH.sub.3 H L-1dN CH S O CH.sub.3 OCH.sub.3 H L-1eN CH S O CH.sub.3 OCH.sub.3 H L-1fN CH S O CH.sub.3 OCH.sub.3 H L-1gN CH S O CH.sub.3 OCH.sub.3 H L-1hN CH S O CH.sub.3 OCH.sub.3 H L-1iN CH S O CH.sub.3 OCH.sub.3 H L-1jN CH S O CH.sub.3 OCH.sub.3 H L-1kN CH S O CH.sub.3 OCH.sub.3 H L-3aN CH S O CH.sub.3 OCH.sub.3 H L-3bN CH S O CH.sub.3 OCH.sub.3 H L-4aN CH S O CH.sub.3 OCH.sub.3 H L-7aN CH S O CH.sub.3 OCH.sub.3 H L-8aN CH S O CH.sub.3 OCH.sub.3 H L-8bN CH S O CH.sub.3 OCH.sub.3 H L-9aN CH S O CH.sub.3 OCH.sub.3 H L-12aN CH S O CH.sub.3 OCH.sub.3 H L-12bN CH S O CH.sub.3 OCH.sub.3 H L-14aN CH S O CH.sub.3 OCH.sub.3 H L-15aN CH S O CH.sub.3 OCH.sub.3 H L-16aN CH S O CH.sub.3 OCH.sub.3 H L-16bN CH S O CH.sub.3 OCH.sub.3 H L-18aN CH S O CH.sub.3 OCH.sub.3 H L-20aN CH S O CH.sub.3 OCH.sub.3 H L-22aN CH S S CH.sub.3 OCH.sub.3 H L-1aN CH S O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH S O OCH.sub.3 OCH.sub.3 H L-1aN CH S O OCH.sub.3 OCH.sub.3 H L-1bN CH S O OCH.sub.3 OCH.sub.3 H L-1cN CH S O OCH.sub.3 OCH.sub.3 H L-1dN CH S O OCH.sub.3 OCH.sub.3 H L-1eN CH S O OCH.sub.3 OCH.sub.3 H L-1fN CH S O OCH.sub.3 OCH.sub.3 H L-1gN CH S O OCH.sub.3 OCH.sub.3 H L-1hN CH S O OCH.sub.3 OCH.sub.3 H L-1iN CH S O OCH.sub.3 OCH.sub.3 H L-1jN CH S O OCH.sub.3 OCH.sub.3 H L-1kN CH S O OCH.sub.3 OCH.sub.3 H L-3aN CH S O OCH.sub.3 OCH.sub.3 H L-3bN CH S O OCH.sub.3 OCH.sub.3 H L-4aN CH S O OCH.sub.3 OCH.sub.3 H L-7aN CH S O OCH.sub.3 OCH.sub.3 H L-8aN CH S O OCH.sub.3 OCH.sub.3 H L-8bN CH S O OCH.sub.3 OCH.sub.3 H L-9aN CH S O OCH.sub.3 OCH.sub.3 H L-12aN CH S O OCH.sub.3 OCH.sub.3 H L-12bN CH S O OCH.sub.3 OCH.sub.3 H L-14aN CH S O OCH.sub.3 OCH.sub.3 H L-15aN CH S O OCH.sub.3 OCH.sub.3 H L-16aN CH S O OCH.sub.3 OCH.sub.3 H L-16bN CH S O OCH.sub.3 OCH.sub.3 H L-18aN CH S O OCH.sub.3 OCH.sub.3 H L-20aN CH S O OCH.sub.3 OCH.sub.3 H L-22aN CH S S OCH.sub.3 OCH.sub.3 H L-1aN CH S O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH O O CH.sub.3 CH.sub.3 H L-1aN CH O O CH.sub.3 CH.sub.3 H L-1bN CH O O CH.sub.3 CH.sub.3 H L-1cN CH O O CH.sub.3 CH.sub.3 H L-1dN CH O O CH.sub.3 CH.sub.3 H L-1eN CH O O CH.sub.3 CH.sub.3 H L-1fN CH O O CH.sub.3 CH.sub.3 H L-1gN CH O O CH.sub.3 CH.sub.3 H L-1hN CH O O CH.sub.3 CH.sub.3 H L-1iN CH O O CH.sub.3 CH.sub.3 H L-1jN CH O O CH.sub.3 CH.sub.3 H L-1kN CH O O CH.sub.3 CH.sub.3 H L-3aN CH O O CH.sub.3 CH.sub.3 H L-3bN CH O O CH.sub.3 CH.sub.3 H L-4aN CH O O CH.sub.3 CH.sub.3 H L-7aN CH O O CH.sub.3 CH.sub.3 H L-8aN CH O O CH.sub.3 CH.sub.3 H L-8bN CH O O CH.sub.3 CH.sub.3 H L-9aN CH O O CH.sub.3 CH.sub.3 H L-12aN CH O O CH.sub.3 CH.sub.3 H L-12bN CH O O CH.sub.3 CH.sub.3 H L-14aN CH O O CH.sub.3 CH.sub.3 H L-15aN CH O O CH.sub.3 CH.sub.3 H L-16aN CH O O CH.sub.3 CH.sub.3 H L-16bN CH O O CH.sub.3 CH.sub.3 H L-18aN CH O O CH.sub.3 CH.sub.3 H L-20aN CH O O CH.sub.3 CH.sub.3 H L-22aN CH O S CH.sub.3 CH.sub.3 H L-1aN CH O O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH O O OCH.sub.3 CH.sub.3 H L-1aN CH O O OCH.sub.3 CH.sub.3 H L-1bN CH O O OCH.sub.3 CH.sub.3 H L-1cN CH O O OCH.sub.3 CH.sub.3 H L-1dN CH O O OCH.sub.3 CH.sub.3 H L-1eN CH O O OCH.sub.3 CH.sub.3 H L-1fN CH O O OCH.sub.3 CH.sub.3 H L-1gN CH O O OCH.sub.3 CH.sub.3 H L-1hN CH O O OCH.sub.3 CH.sub.3 H L-1iN CH O O OCH.sub.3 CH.sub.3 H L-1jN CH O O OCH.sub.3 CH.sub.3 H L-1kN CH O O OCH.sub.3 CH.sub.3 H L-3aN CH O O OCH.sub.3 CH.sub.3 H L-3bN CH O O OCH.sub.3 CH.sub.3 H L-4aN CH O O OCH.sub.3 CH.sub.3 H L-7aN CH O O OCH.sub.3 CH.sub.3 H L-8aN CH O O OCH.sub.3 CH.sub. 3 H L-8bN CH O O OCH.sub.3 CH.sub.3 H L-9aN CH O O OCH.sub.3 CH.sub.3 H L-12aN CH O O OCH.sub.3 CH.sub.3 H L-12bN CH O O OCH.sub.3 CH.sub.3 H L-14aN CH O O OCH.sub.3 CH.sub.3 H L-15aN CH O O OCH.sub.3 CH.sub.3 H L-16aN CH O O OCH.sub.3 CH.sub.3 H L-16bN CH O O CH.sub.3 CH.sub.3 H L-18aN CH O O OCH.sub.3 CH.sub.3 H L-20aN CH O O OCH.sub.3 CH.sub.3 H L-22aN CH O S OCH.sub.3 CH.sub.3 H L-1aN CH O O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH O O CH.sub.3 OCH.sub.3 H L-1aN CH O O CH.sub.3 OCH.sub.3 H L-1bN CH O O CH.sub.3 OCH.sub.3 H L-1cN CH O O CH.sub.3 OCH.sub.3 H L-1dN CH O O CH.sub.3 OCH.sub.3 H L-1eN CH O O CH.sub.3 OCH.sub.3 H L-1fN CH O O CH.sub.3 OCH.sub.3 H L-1gN CH O O CH.sub.3 OCH.sub.3 H L-1hN CH O O CH.sub.3 OCH.sub.3 H L-1iN CH O O CH.sub.3 OCH.sub.3 H L-1jN CH O O CH.sub.3 OCH.sub.3 H L-1kN CH O O CH.sub.3 OCH.sub.3 H L-3aN CH O O CH.sub.3 OCH.sub.3 H L-3bN CH O O CH.sub.3 OCH.sub.3 H L-4aN CH O O CH.sub.3 OCH.sub.3 H L-7aN CH O O CH.sub.3 OCH.sub.3 H L-8aN CH O O CH.sub.3 OCH.sub.3 H L-8bN CH O O CH.sub.3 OCH.sub.3 H L-9aN CH O O CH.sub.3 OCH.sub.3 H L-12aN CH O O CH.sub.3 OCH.sub.3 H L-12bN CH O O CH.sub.3 OCH.sub.3 H L-14aN CH O O CH.sub.3 OCH.sub.3 H L-15aN CH O O CH.sub.3 OCH.sub.3 H L-16aN CH O O CH.sub.3 OCH.sub.3 H L-16bN CH O O CH.sub.3 OCH.sub.3 H L-18aN CH O O CH.sub.3 OCH.sub.3 H L-20aN CH O O CH.sub.3 OCH.sub.3 H L-22aN CH O S CH.sub.3 OCH.sub.3 H L-1aN CH O O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH O O OCH.sub.3 OCH.sub.3 H L-1aN CH O O OCH.sub.3 OCH.sub.3 H L-1bN CH O O OCH.sub.3 OCH.sub.3 H L-1cN CH O O OCH.sub.3 OCH.sub.3 H L-1dN CH O O OCH.sub.3 OCH.sub.3 H L-1eN CH O O OCH.sub.3 OCH.sub.3 H L-1fN CH O O OCH.sub.3 OCH.sub.3 H L-1gN CH O O OCH.sub.3 OCH.sub.3 H L-1hN CH O O OCH.sub.3 OCH.sub.3 H L-1iN CH O O OCH.sub.3 OCH.sub.3 H L-1jN CH O O OCH.sub.3 OCH.sub.3 H L-1kN CH O O OCH.sub.3 OCH.sub.3 H L-3aN CH O O OCH.sub.3 OCH.sub.3 H L-3bN CH O O OCH.sub.3 OCH.sub.3 H L-4aN CH O O OCH.sub.3 OCH.sub.3 H L-7aN CH O O OCH.sub.3 OCH.sub.3 H L-8aN CH O O OCH.sub.3 OCH.sub.3 H L-8bN CH O O OCH.sub.3 OCH.sub.3 H L-9aN CH O O OCH.sub. 3 OCH.sub.3 H L-12aN CH O O OCH.sub.3 OCH.sub.3 H L-12bN CH O O OCH.sub.3 OCH.sub.3 H L-14aN CH O O OCH.sub.3 OCH.sub.3 H L-15aN CH O O OCH.sub.3 OCH.sub.3 H L-16aN CH O O OCH.sub.3 OCH.sub.3 H L-16bN CH O O OCH.sub.3 OCH.sub.3 H L-18aN CH O O OCH.sub.3 OCH.sub.3 H L-20aN CH O O OCH.sub.3 OCH.sub.3 H L-22aN CH O S OCH.sub.3 OCH.sub.3 H L-1aN CH O O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1cCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1dCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1eCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1fCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1gCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1hCH CH NCH.sub.3 O CH.sub. 3 CH.sub.3 H L-1iCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1jCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1kCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-3aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-3bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-4aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-7aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-8aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-8bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-9aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-12aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-12bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-14aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-15aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-16aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-16bCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-18aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-20aCH CH NCH.sub.3 O CH.sub.3 CH.sub. 3 H L-22aCH CH NCH.sub.3 S CH.sub.3 CH.sub.3 H L-1aCH CH NCH.sub.3 O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1cCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1dCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1eCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1fCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1gCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1hCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1iCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1jCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1kCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-3aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-3bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-4aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-7aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-8aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-8bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-9aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-12aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-12bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-14aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-15aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-16aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-16bCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-18aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-20aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-22aCH CH NCH.sub.3 S OCH.sub.3 CH.sub.3 H L-1aCH CH NCH.sub.3 O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1cCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1dCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1eCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1fCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1gCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1hCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1iCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1jCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1kCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-3aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-3bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-4aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-7aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-8aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-8bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-9aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-12aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-12bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-14aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-15aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-16aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-16bCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-18aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-20aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-22aCH CH NCH.sub.3 S CH.sub.3 OCH.sub.3 H L-1aCH CH NCH.sub.3 O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1cCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1dCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1eCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1fCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1gCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1hCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1iCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1jCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1kCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-3aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-3bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-4aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-7aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-8aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-8bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-9aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-12aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-12bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-14aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-15aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-16aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-16bCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-18aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-20aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-22aCH CH NCH.sub.3 S OCH.sub.3 OCH.sub.3 H L-1aCH CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1aN CH NCH.sub. 3 O CH.sub.3 CH.sub.3 H L-1bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1cN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1dN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1eN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1fN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1gN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1hN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1iN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1jN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-1kN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-3aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-3bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-4aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-7aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-8aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-8bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-9aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-12aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-12bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-14aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-15aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-16aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-16bN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-18aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-20aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 H L-22aN CH NCH.sub.3 S CH.sub.3 CH.sub.3 H L-1aN CH NCH.sub.3 O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1cN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1dN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1eN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1fN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1gN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1hN CH NCH.sub.3 O OCH.sub. 3 CH.sub.3 H L-1iN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1jN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-1kN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-3aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-3bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-4aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-7aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-8aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-8bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-9aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-12aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-12bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-14aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-15aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-16aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-16bN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-18aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 H L-20aN CH NCH.sub.3 O OCH.sub.3 CH.sub. 3 H L-22aN CH NCH.sub.3 S OCH.sub.3 CH.sub.3 H L-1aN CH NCH.sub.3 O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1cN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1dN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1eN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1fN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1gN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1hN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1iN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1jN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-1kN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-3aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-3bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-4aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-7aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-8aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-8bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-9aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-12aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-12bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-14aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-15aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-16aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-16bN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-18aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-20aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 H L-22aN CH NCH.sub.3 S CH.sub.3 OCH.sub.3 H L-1aN CH NCH.sub.3 O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1cN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1dN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1eN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1fN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1gN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1hN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1iN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1jN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-1kN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-3aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-3bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-4aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-7aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-8aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-8bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-9aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-12aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-12bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-14aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-15aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-16aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-16bN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-18aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-20aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 H L-22aN CH NCH.sub.3 S OCH.sub.3 OCH.sub.3 H L-1aN CH NCH.sub.3 O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1a______________________________________
TABLE 7______________________________________General Formula 7Z Z.sub.1 Z.sub.2 W X.sub.a Y R L m.p.(.degree. C.)______________________________________CH N CH O CH.sub.3 CH.sub.3 H L-1aCH N CH O CH.sub.3 OCH.sub.3 H L-1aN N CH O CH.sub.3 CH.sub.3 H L-1aN N CH O CH.sub.3 OCH.sub.3 H L-1aCH N N O CH.sub.3 OCH.sub.3 H L-1aCH N N O CH.sub.3 OCH.sub.3 H L-1aN N N O CH.sub.3 CH.sub.3 H L-1aN N N O CH.sub.3 OCH.sub.3 H L-1aCH CH CH O CH.sub.3 CH.sub.3 H L-1aCH CH CH O CH.sub.3 OCH.sub.3 H L-1aN CH CH O CH.sub.3 CH.sub.3 H L-1aN CH CH O CH.sub.3 OCH.sub.3 H L-1aCH CH N O CH.sub.3 CH.sub.3 H L-1aCH CH N O CH.sub.3 OCH.sub.3 H L-1aN CH N O CH.sub.3 CH.sub.3 H L-1aN CH N O CH.sub.3 OCH.sub.3 H L-1a______________________________________
TABLE 8______________________________________General Formula 8Z Z.sub.4 Z.sub.2 W X Y R L m.p.(.degree. C.)______________________________________CH NCH.sub.3 CH O CH.sub.3 CH.sub.3 H L-1aCH NCH.sub.3 CH O OCH.sub.3 CH.sub.3 H L-1aCH NCH.sub.3 CH O CH.sub.3 OCH.sub.3 H L-1aCH NCH.sub.3 CH O OCH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 OCH.sub.3 H L-1aCH NCH.sub.3 N O CH.sub.3 CH.sub.3 H L-1aCH NCH.sub.3 N O OCH.sub.3 CH.sub.3 H L-1aCH NCH.sub.3 N O CH.sub.3 OCH.sub.3 H L-1aCH NCH.sub.3 N O OCH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 OCH.sub.3 H L-1aCH O CH O CH.sub.3 CH.sub.3 H L-1aCH O CH O OCH.sub.3 CH.sub.3 H L-1aCH O CH O CH.sub.3 OCH.sub.3 H L-1aCH O CH O OCH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 OCH.sub.3 H L-1a______________________________________
TABLE 9______________________________________General Formula 9Z Z.sub.4 Z.sub.2 W X Y R L m.p.(.degree. C.)______________________________________CH NCH.sub.3 CH O CH.sub.3 CH.sub.3 H L-1aCH NCH.sub.3 CH O OCH.sub.3 CH.sub.3 H L-1aCH NCH.sub.3 CH O CH.sub.3 OCH.sub.3 H L-1aCH NCH.sub.3 CH O OCH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 OCH.sub.3 H L-1aCH NCH.sub.3 N O CH.sub.3 CH.sub.3 H L-1aCH NCH.sub.3 N O OCH.sub.3 CH.sub.3 H L-1aCH NCH.sub.3 N O CH.sub.3 OCH.sub.3 H L-1aCH NCH.sub.3 N O OCH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 OCH.sub.3 H L-1aCH O CH O CH.sub.3 CH.sub.3 H L-1aCH O CH O OCH.sub.3 CH.sub.3 H L-1aCH O CH O CH.sub.3 OCH.sub.3 H L-1aCH O CH O OCH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 CH.sub.3 H L-1aN NCH.sub.3 CH O CH.sub.3 OCH.sub.3 H L-1aN NCH.sub.3 CH O OCH.sub.3 OCH.sub.3 H L-1a______________________________________
TABLE 10______________________________________General Formula 10Z.sub.1 Z.sub.2 Z.sub.3 X W R L m.p.(.degree. C.)______________________________________N CH CH CH.sub.3 O H L-1aN CH N CH.sub.3 O H L-1aN N CH CH.sub.3 O H L-1aN N N CH.sub.3 O H L-1aCH CH CH CH.sub.3 O H L-1aCH CH N CH.sub.3 O H L-1aCH N CH CH.sub.3 O H L-1aCH N N CH.sub.3 O H L-1aN CH CH OCH.sub.3 O H L-1aN CH N OCH.sub.3 O H L-1aN N CH OCH.sub.3 O H L-1aN N N OCH.sub.3 O H L-1aCH CH CH OCH.sub.3 O H L-1aCH CH N OCH.sub.3 O H L-1aCH N CH OCH.sub.3 O H L-1aCH N N OCH.sub.3 O H L-1a______________________________________
TABLE 11______________________________________General Formula 11Z.sub.4 Z.sub.1 Z.sub.2 X.sub.d Y W R L m.p.(.degree. C.)______________________________________O CH N H CH.sub.3 O H L-1aO CH CH H CH.sub.3 O H L-1aO N N H CH.sub.3 O H L-1aO N CH H CH.sub.3 O H L-1aS CH N H CH.sub.3 O H L-1aS CH CH H CH.sub.3 O H L-1aS N N H CH.sub.3 O H L-1aS N CH H CH.sub.3 O H L-1aNCH.sub.3 CH N H CH.sub.3 O H L-1aNCH.sub.3 CH CH H CH.sub.3 O H L-1aNCH.sub.3 N N H CH.sub.3 O H L-1aNCH.sub.3 N CH H CH.sub.3 O H L-1aCH.sub.2 CH N H CH.sub.3 O H L-1aCH.sub.2 CH CH H CH.sub.3 O H L-1aCH.sub.2 N N H CH.sub.3 O H L-1aCH.sub.2 N CH H CH.sub.3 O H L-1aO CH N CH.sub.3 CH.sub.3 O H L-1aO CH CH CH.sub.3 CH.sub.3 O H L-1aO N N CH.sub.3 CH.sub.3 O H L-1aO N CH CH.sub.3 CH.sub.3 O H L-1aS CH N CH.sub.3 CH.sub.3 O H L-1aS CH CH CH.sub.3 CH.sub.3 O H L-1aS N N CH.sub.3 CH.sub.3 O H L-1aS N CH CH.sub.3 CH.sub.3 O H L-1aNCH.sub.3 CH N CH.sub.3 CH.sub.3 O H L-1aNCH.sub.3 CH CH CH.sub.3 CH.sub.3 O H L-1aNCH.sub.3 CH CH CH.sub.3 CH.sub.3 O H L-1aNCH.sub.3 N N CH.sub.3 CH.sub.3 O H L-1aCH.sub.2 CH N CH.sub.3 CH.sub.3 O H L-1aCH.sub.2 CH CH CH.sub.3 CH.sub.3 O H L-1aCH.sub.2 N N CH.sub.3 CH.sub.3 O H L-1aCH.sub.2 N CH CH.sub.3 CH.sub.3 O H L-1aO CH N H OCH.sub.3 O H L-1aO CH CH H OCH.sub.3 O H L-1aO N N H OCH.sub.3 O H L-1aO N CH H OCH.sub.3 O H L-1aS CH N H OCH.sub.3 O H L-1aS CH CH H OCH.sub.3 O H L-1aS N N H OCH.sub.3 O H L-1aS N CH H OCH.sub.3 O H L-1aNCH.sub.3 CH N H OCH.sub.3 O H L-1aNCH.sub.3 CH CH H OCH.sub.3 O H L-1aNCH.sub.3 N N H OCH.sub.3 O H L-1aNCH.sub.3 N CH H OCH.sub.3 O H L-1aCH.sub.2 CH N H OCH.sub.3 O H L-1aCH.sub.2 CH CH H OCH.sub.3 O H L-1aCH.sub.2 N N H OCH.sub.3 O H L-1aCH.sub.2 N CH H OCH.sub.3 O H L-1aO CH N CH.sub.3 OCH.sub.3 O H L-1aO CH CH CH.sub.3 OCH.sub.3 O H L-1aO N N CH.sub.3 OCH.sub.3 O H L-1aO N CH CH.sub.3 OCH.sub.3 O H L-1aS CH N CH.sub.3 OCH.sub.3 O H L-1aS CH CH CH.sub.3 OCH.sub.3 O H L-1aS N N CH.sub.3 OCH.sub.3 O H L-1aS N CH CH.sub.3 OCH.sub.3 O H L-1aNCH.sub.3 CH N CH.sub.3 OCH.sub. 3 O H L-1aNCH.sub.3 CH CH CH.sub.3 OCH.sub.3 O H L-1aNCH.sub.3 N N CH.sub.3 OCH.sub.3 O H L-1aNCH.sub.3 N CH CH.sub.3 OCH.sub.3 O H L-1aCH.sub.2 CH N CH.sub.3 OCH.sub.3 O H L-1aCH.sub.2 CH CH CH.sub.3 OCH.sub.3 O H L-1aCH.sub.2 N N CH.sub.3 OCH.sub.3 O H L-1aCH.sub.2 N CH CH.sub.3 OCH.sub.3 O H L-1a______________________________________
TABLE 12______________________________________General Formula 12Z.sub.4 Z.sub.1 Z.sub.2 m' Y W R L m.p.(.degree. C.)______________________________________O CH N 2 CH.sub.3 O H L-1aO CH CH 2 CH.sub.3 O H L-1aO N N 2 CH.sub.3 O H L-1aO N CH 2 CH.sub.3 O H L-1aS CH N 2 CH.sub.3 O H L-1aS CH CH 2 CH.sub.3 O H L-1aS N N 2 CH.sub.3 O H L-1aS N CH 2 CH.sub.3 O H L-1aNCH.sub.3 CH N 2 CH.sub.3 O H L-1aNCH.sub.3 CH CH 2 CH.sub.3 O H L-1aNCH.sub.3 N N 2 CH.sub.3 O H L-1aNCH.sub.3 N CH 2 CH.sub.3 O H L-1aCH.sub.2 CH N 2 CH.sub.3 O H L-1aCH.sub.2 CH CH 2 CH.sub.3 O H L-1aCH.sub.2 N N 2 CH.sub.3 O H L-1aCH.sub.2 N CH 2 CH.sub.3 O H L-1aO CH N 3 CH.sub.3 O H L-1aO CH CH 3 CH.sub.3 O H L-1aO N N 3 CH.sub.3 O H L-1aO N CH 3 CH.sub.3 O H L-1aS CH N 3 CH.sub.3 O H L-1aS CH CH 3 CH.sub.3 O H L-1aS N N 3 CH.sub.3 O H L-1aS N CH 3 CH.sub.3 O H L-1aNCH.sub.3 CH N 3 CH.sub.3 O H L-1aNCH.sub.3 CH CH 3 CH.sub.3 O H L-1aNCH.sub.3 N N 3 CH.sub.3 O H L-1aNCH.sub.3 N CH 3 CH.sub.3 O H L-1aCH.sub.2 CH N 3 CH.sub.3 O H L-1aCH.sub.2 CH CH 3 CH.sub.3 O H L-1aCH.sub.2 N N 3 CH.sub.3 O H L-1aCH.sub.2 N CH 3 CH.sub.3 O H L-1aO CH N 2 OCH.sub.3 O H L-1aO CH CH 2 OCH.sub.3 O H L-1aO N N 2 OCH.sub.3 O H L-1aO N CH 2 OCH.sub.3 O H L-1aS CH N 2 OCH.sub.3 O H L-1aS CH CH 2 OCH.sub.3 O H L-1aS N N 2 OCH.sub.3 O H L-1aS N CH 2 OCH.sub.3 O H L-1aNCH.sub.3 CH N 2 OCH.sub.3 O H L-1aNCH.sub.3 CH CH 2 OCH.sub.3 O H L-1aNCH.sub.3 N N 2 OCH.sub.3 O H L-1aNCH.sub.3 N CH 2 OCH.sub.3 O H L-1aCH.sub.2 CH N 2 OCH.sub.3 O H L-1aCH.sub.2 CH CH 2 OCH.sub.3 O H L-1aCH.sub.2 N N 2 OCH.sub.3 O H L-1aCH.sub.2 N CH 2 OCH.sub.3 O H L-1aO CH N 3 OCH.sub.3 O H L-1aO CH CH 3 OCH.sub.3 O H L-1aO N N 3 OCH.sub.3 O H L-1aO N CH 3 OCH.sub.3 O H L-1aS CH N 3 OCH.sub.3 O H L-1aS CH CH 3 OCH.sub.3 O H L-1aS N N 3 OCH.sub.3 O H L-1aS N CH 3 OCH.sub.3 O H L-1aNCH.sub.3 CH N 3 OCH.sub.3 O H L-1aNCH.sub.3 CH CH 3 OCH.sub.3 O H L-1aNCH.sub.3 N N 3 OCH.sub.3 O H L-1aNCH.sub. 3 N CH 3 OCH.sub.3 O H L-1aCH.sub.2 CH N 3 OCH.sub.3 O H L-1aCH.sub.2 CH CH 3 OCH.sub.3 O H L-1aCH.sub.2 N N 3 OCH.sub.3 O H L-1aCH.sub.2 N CH 3 OCH.sub.3 O H L-1a______________________________________
TABLE 13______________________________________General Formula 13Z.sub.4 Z.sub.1 Z.sub.2 X.sub.d X W R L m.p.(.degree. C.)______________________________________O CH N H CH.sub.3 O H L-1aO CH CH H CH.sub.3 O H L-1aO N N H CH.sub.3 O H L-1aO N CH H CH.sub.3 O H L-1aS CH N H CH.sub.3 O H L-1aS CH CH H CH.sub.3 O H L-1aS N N H CH.sub.3 O H L-1aS N CH H CH.sub.3 O H L-1aNCH.sub.3 CH N H CH.sub.3 O H L-1aNCH.sub.3 CH CH H CH.sub.3 O H L-1aNCH.sub.3 N N H CH.sub.3 O H L-1aNCH.sub.3 N CH H CH.sub.3 O H L-1aCH.sub.2 CH N H CH.sub.3 O H L-1aCH.sub.2 CH CH H CH.sub.3 O H L-1aCH.sub.2 N N H CH.sub.3 O H L-1aCH.sub.2 N CH H CH.sub.3 O H L-1aO CH N CH.sub.3 CH.sub.3 O H L-1aO CH CH CH.sub.3 CH.sub.3 O H L-1aO N N CH.sub.3 CH.sub.3 O H L-1aO N CH CH.sub.3 CH.sub.3 O H L-1aS CH N CH.sub.3 CH.sub.3 O H L-1aS CH CH CH.sub.3 CH.sub.3 O H L-1aS N N CH.sub.3 CH.sub.3 O H L-1aS N CH CH.sub.3 CH.sub.3 O H L-1aNCH.sub.3 CH N CH.sub.3 CH.sub.3 O H L-1aNCH.sub.3 CH CH CH.sub.3 CH.sub.3 O H L-1aNCH.sub.3 N N CH.sub.3 CH.sub.3 O H L-1aNCH.sub.3 N CH CH.sub.3 CH.sub.3 O H L-1aCH.sub.2 CH N CH.sub.3 CH.sub.3 O H L-1aCH.sub.2 CH CH CH.sub.3 CH.sub.3 O H L-1aCH.sub.2 N N CH.sub.3 CH.sub.3 O H L-1aCH.sub.2 N CH CH.sub.3 CH.sub.3 O H L-1aO CH N H OCH.sub.3 O H L-1aO CH CH H OCH.sub.3 O H L-1aO N N H OCH.sub.3 O H L-1aO N CH H OCH.sub.3 O H L-1aS CH N H OCH.sub.3 O H L-1aS CH CH H OCH.sub.3 O H L-1aS N N H OCH.sub.3 O H L-1aS N CH H OCH.sub.3 O H L-1aNCH.sub.3 CH N H OCH.sub.3 O H L-1aNCH.sub.3 CH CH H OCH.sub.3 O H L-1aNCH.sub.3 N N H OCH.sub.3 O H L-1aNCH.sub.3 N CH H OCH.sub.3 O H L-1aCH.sub.2 CH N H OCH.sub.3 O H L-1aCH.sub.2 CH CH H OCH.sub.3 O H L-1aCH.sub.2 N N H OCH.sub.3 O H L-1aCH.sub.2 N CH H OCH.sub.3 O H L-1aO CH N CH.sub.3 OCH.sub.3 O H L-1aO CH CH CH.sub.3 OCH.sub.3 O H L-1aO N N CH.sub.3 OCH.sub.3 O H L-1aO N CH CH.sub.3 OCH.sub.3 O H L-1aS CH N CH.sub.3 OCH.sub.3 O H L-1aS CH CH CH.sub.3 OCH.sub.3 O H L-1aS N N CH.sub.3 OCH.sub.3 O H L-1aS N CH CH.sub.3 OCH.sub.3 O H L-1aNCH.sub.3 CH N CH.sub.3 OCH.sub. 3 O H L-1aNCH.sub.3 CH CH CH.sub.3 OCH.sub.3 O H L-1aNCH.sub.3 N N CH.sub.3 OCH.sub.3 O H L-1aNCH.sub.3 N CH CH.sub.3 OCH.sub.3 O H L-1aCH.sub.2 CH N CH.sub.3 OCH.sub.3 O H L-1aCH.sub.2 CH CH CH.sub.3 OCH.sub.3 O H L-1aCH.sub.2 N N CH.sub.3 OCH.sub.3 O H L-1aCH.sub.2 N CH CH.sub.3 OCH.sub.3 O H L-1a______________________________________
TABLE 14______________________________________General Formula 14Z.sub.4 Z.sub.1 Z.sub.2 m' X W R L m.p.(.degree. C.)______________________________________O CH N 2 CH.sub.3 O H L-1aO CH CH 2 CH.sub.3 O H L-1aO N N 2 CH.sub.3 O H L-1aO N CH 2 CH.sub.3 O H L-1aS CH N 2 CH.sub.3 O H L-1aS CH CH 2 CH.sub.3 O H L-1aS N N 2 CH.sub.3 O H L-1aS N CH 2 CH.sub.3 O H L-1aNCH.sub.3 CH N 2 CH.sub.3 O H L-1aNCH.sub.3 CH CH 2 CH.sub.3 O H L-1aNCH.sub.3 N N 2 CH.sub.3 O H L-1aNCH.sub.3 N CH 2 CH.sub.3 O H L-1aCH.sub.2 CH N 2 CH.sub.3 O H L-1aCH.sub.2 CH CH 2 CH.sub.3 O H L-1aCH.sub.2 N N 2 CH.sub.3 O H L-1aCH.sub.2 N CH 2 CH.sub.3 O H L-1aO CH N 3 CH.sub.3 O H L-1aO CH CH 3 CH.sub.3 O H L-1aO N N 3 CH.sub.3 O H L-1aO N CH 3 CH.sub.3 O H L-1aS CH N 3 CH.sub.3 O H L-1aS CH CH 3 CH.sub.3 O H L-1aS N N 3 CH.sub.3 O H L-1aS N CH 3 CH.sub.3 O H L-1aNCH.sub.3 CH N 3 CH.sub.3 O H L-1aNCH.sub.3 CH CH 3 CH.sub.3 O H L-1aNCH.sub.3 N N 3 CH.sub.3 O H L-1aNCH.sub.3 N CH 3 CH.sub.3 O H L-1aCH.sub.2 CH N 3 CH.sub.3 O H L-1aCH.sub.2 CH CH 3 CH.sub.3 O H L-1aCH.sub.2 N N 3 CH.sub.3 O H L-1aCH.sub.2 N CH 3 CH.sub.3 O H L-1a______________________________________
TABLE 15______________________________________General Formula 15Z.sub.1 Z.sub.2 W X Y R L m.p.(.degree.C.)______________________________________N CH O CH.sub.3 CH.sub.3 H L-1aN CH O CH.sub.3 CH.sub.3 H L-1bN CH O CH.sub.3 CH.sub.3 H L-1cN CH O CH.sub.3 CH.sub.3 H L-1dN CH O CH.sub.3 CH.sub.3 H L-1eN CH O CH.sub.3 CH.sub.3 H L-1fN CH O CH.sub.3 CH.sub.3 H L-1gN CH O CH.sub.3 CH.sub.3 H L-1hN CH O CH.sub.3 CH.sub.3 H L-1iN CH O CH.sub.3 CH.sub.3 H L-3aN CH O CH.sub.3 CH.sub.3 H L-3bN CH O CH.sub.3 CH.sub.3 H L-4aN CH O CH.sub.3 CH.sub.3 H L-7aN CH O CH.sub.3 CH.sub.3 H L-8aN CH O CH.sub.3 CH.sub.3 H L-8bN CH O CH.sub.3 CH.sub.3 H L-9aN CH O CH.sub.3 CH.sub.3 H L-12aN CH O CH.sub.3 CH.sub.3 H L-12bN CH O CH.sub.3 CH.sub.3 H L-14aN CH O CH.sub.3 CH.sub.3 H L-15aN CH O CH.sub.3 CH.sub.3 H L-16aN CH O CH.sub.3 CH.sub.3 H L-16bN CH O CH.sub.3 CH.sub.3 H L-18aN CH O CH.sub.3 CH.sub.3 H L-20aN CH O CH.sub.3 CH.sub.3 H L-22aN CH S CH.sub.3 CH.sub.3 H L-1aN CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH O OCH.sub.3 CH.sub.3 H L-1aN CH O OCH.sub.3 CH.sub.3 H L-1bN CH O OCH.sub.3 CH.sub.3 H L-1cN CH O OCH.sub.3 CH.sub.3 H L-1dN CH O OCH.sub.3 CH.sub.3 H L-1eN CH O OCH.sub.3 CH.sub.3 H L-1fN CH O OCH.sub.3 CH.sub.3 H L-1gN CH O OCH.sub.3 CH.sub.3 H L-1hN CH O OCH.sub.3 CH.sub.3 H L-1iN CH O OCH.sub.3 CH.sub.3 H L-3aN CH O OCH.sub.3 CH.sub.3 H L-3bN CH O OCH.sub.3 CH.sub.3 H L-4aN CH O OCH.sub.3 CH.sub.3 H L-7aN CH O OCH.sub.3 CH.sub.3 H L-8aN CH O OCH.sub.3 CH.sub.3 H L-8bN CH O OCH.sub.3 CH.sub.3 H L-9aN CH O OCH.sub.3 CH.sub.3 H L-12aN CH O OCH.sub.3 CH.sub.3 H L-12bN CH O OCH.sub.3 CH.sub.3 H L-14aN CH O OCH.sub.3 CH.sub.3 H L-15aN CH O OCH.sub.3 CH.sub.3 H L-16aN CH O OCH.sub.3 CH.sub.3 H L-16bN CH O OCH.sub.3 CH.sub.3 H L-18aN CH O OCH.sub.3 CH.sub.3 H L-20aN CH O OCH.sub.3 CH.sub.3 H L-22aN CH S OCH.sub.3 CH.sub.3 H L-1aN CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN CH O CH.sub.3 OCH.sub.3 H L-1aN CH O CH.sub.3 OCH.sub.3 H L-1bN CH O CH.sub.3 OCH.sub.3 H L-1cN CH O CH.sub.3 OCH.sub.3 H L-1dN CH O CH.sub.3 OCH.sub.3 H L-1eN CH O CH.sub.3 OCH.sub.3 H L-1fN CH O CH.sub.3 OCH.sub.3 H L-1gN CH O CH.sub.3 OCH.sub.3 H L-1hN CH O CH.sub.3 OCH.sub.3 H L-1iN CH O CH.sub.3 OCH.sub.3 H L-3aN CH O CH.sub.3 OCH.sub.3 H L-3bN CH O CH.sub.3 OCH.sub.3 H L-4aN CH O CH.sub.3 OCH.sub.3 H L-7aN CH O CH.sub.3 OCH.sub.3 H L-8aN CH O CH.sub.3 OCH.sub.3 H L-8bN CH O CH.sub.3 OCH.sub.3 H L-9aN CH O CH.sub.3 OCH.sub.3 H L-12aN CH O CH.sub.3 OCH.sub.3 H L-12bN CH O CH.sub.3 OCH.sub.3 H L-14aN CH O CH.sub.3 OCH.sub.3 H L-15aN CH O CH.sub.3 OCH.sub.3 H L-16aN CH O CH.sub.3 OCH.sub.3 H L-16bN CH O CH.sub.3 OCH.sub.3 H L-18aN CH O CH.sub.3 OCH.sub.3 H L-20aN CH O CH.sub.3 OCH.sub.3 H L-22aN CH S CH.sub.3 OCH.sub.3 H L-1aN CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN CH O OCH.sub.3 OCH.sub.3 H L-1aN CH O OCH.sub.3 OCH.sub.3 H L-1bN CH O OCH.sub.3 OCH.sub.3 H L-1cN CH O OCH.sub. 3 OCH.sub.3 H L-1dN CH O OCH.sub.3 OCH.sub.3 H L-1eN CH O OCH.sub.3 OCH.sub.3 H L-1fN CH O OCH.sub.3 OCH.sub.3 H L-1gN CH O OCH.sub.3 OCH.sub.3 H L-1hN CH O OCH.sub.3 OCH.sub.3 H L-1iN CH O OCH.sub.3 OCH.sub.3 H L-3aN CH O OCH.sub.3 OCH.sub.3 H L-3bN CH O OCH.sub.3 OCH.sub.3 H L-4aN CH O OCH.sub.3 OCH.sub.3 H L-7aN CH O OCH.sub.3 OCH.sub.3 H L-8aN CH O OCH.sub.3 OCH.sub.3 H L-8bN CH O OCH.sub.3 OCH.sub.3 H L-9aN CH O OCH.sub.3 OCH.sub.3 H L-12aN CH O OCH.sub.3 OCH.sub.3 H L-12bN CH O OCH.sub.3 OCH.sub.3 H L-14aN CH O OCH.sub.3 OCH.sub.3 H L-15aN CH O OCH.sub.3 OCH.sub.3 H L-16aN CH O OCH.sub.3 OCH.sub.3 H L-16bN CH O OCH.sub.3 OCH.sub.3 H L-18aN CH O OCH.sub.3 OCH.sub.3 H L-20aN CH O OCH.sub.3 OCH.sub.3 H L-22aN CH S OCH.sub.3 OCH.sub. 3 H L-1aN CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N O CH.sub.3 CH.sub.3 H L-1aN N O CH.sub.3 CH.sub.3 H L-1bN N O CH.sub.3 CH.sub.3 H L-1cN N O CH.sub.3 CH.sub.3 H L-1dN N O CH.sub.3 CH.sub.3 H L-1eN N O CH.sub.3 CH.sub.3 H L-1fN N O CH.sub.3 CH.sub.3 H L-1gN N O CH.sub.3 CH.sub.3 H L-1hN N O CH.sub.3 CH.sub.3 H L-1iN N O CH.sub.3 CH.sub.3 H L-3aN N O CH.sub.3 CH.sub.3 H L-3bN N O CH.sub.3 CH.sub.3 H L-4aN N O CH.sub.3 CH.sub.3 H L-7aN N O CH.sub.3 CH.sub.3 H L-8aN N O CH.sub.3 CH.sub.3 H L-8bN N O CH.sub.3 CH.sub.3 H L-9aN N O CH.sub.3 CH.sub.3 H L-12aN N O CH.sub.3 CH.sub.3 H L-12bN N O CH.sub.3 CH.sub.3 H L-14aN N O CH.sub.3 CH.sub.3 H L-15aN N O CH.sub.3 CH.sub.3 H L-16aN N O CH.sub.3 CH.sub.3 H L-16bN N O CH.sub.3 CH.sub.3 H L-18aN N O CH.sub.3 CH.sub.3 H L-20aN N O CH.sub.3 CH.sub.3 H L-22aN N S CH.sub.3 CH.sub.3 H L-1aN N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aN N O OCH.sub.3 CH.sub.3 H L-1aN N O OCH.sub.3 CH.sub.3 H L-1bN N O OCH.sub.3 CH.sub.3 H L-1cN N O OCH.sub.3 CH.sub.3 H L-1dN N O OCH.sub.3 CH.sub.3 H L-1eN N O OCH.sub.3 CH.sub.3 H L-1fN N O OCH.sub.3 CH.sub.3 H L-1gN N O OCH.sub.3 CH.sub.3 H L-1hN N O OCH.sub.3 CH.sub.3 H L-1iN N O OCH.sub.3 CH.sub.3 H L-3aN N O OCH.sub.3 CH.sub.3 H L-3bN N O OCH.sub.3 CH.sub.3 H L-4aN N O OCH.sub.3 CH.sub.3 H L-7aN N O OCH.sub.3 CH.sub.3 H L-8aN N O OCH.sub.3 CH.sub.3 H L-8bN N O OCH.sub.3 CH.sub.3 H L-9aN N O OCH.sub.3 CH.sub.3 H L-12aN N O OCH.sub.3 CH.sub.3 H L-12bN N O OCH.sub.3 CH.sub.3 H L-14aN N O OCH.sub.3 CH.sub.3 H L-15aN N O OCH.sub.3 CH.sub.3 H L-16aN N O OCH.sub.3 CH.sub.3 H L-16bN N O OCH.sub.3 CH.sub.3 H L-18aN N O OCH.sub.3 CH.sub.3 H L-20aN N O OCH.sub.3 CH.sub.3 H L-22aN N S OCH.sub.3 CH.sub.3 H L-1aN N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aN N O CH.sub.3 OCH.sub.3 H L-1aN N O CH.sub.3 OCH.sub.3 H L-1bN N O CH.sub.3 OCH.sub.3 H L-1cN N O CH.sub.3 OCH.sub.3 H L-1dN N O CH.sub.3 OCH.sub.3 H L-1eN N O CH.sub.3 OCH.sub.3 H L-1fN N O CH.sub.3 OCH.sub.3 H L-1gN N O CH.sub.3 OCH.sub.3 H L-1hN N O CH.sub.3 OCH.sub.3 H L-1iN N O CH.sub.3 OCH.sub.3 H L-3aN N O CH.sub.3 OCH.sub.3 H L-3bN N O CH.sub.3 OCH.sub.3 H L-4aN N O CH.sub.3 OCH.sub.3 H L-7aN N O CH.sub.3 OCH.sub.3 H L-8aN N O CH.sub.3 OCH.sub.3 H L-8bN N O CH.sub.3 OCH.sub.3 H L-9aN N O CH.sub.3 OCH.sub.3 H L-12aN N O CH.sub.3 OCH.sub.3 H L-12bN N O CH.sub.3 OCH.sub.3 H L-14aN N O CH.sub.3 OCH.sub.3 H L-15aN N O CH.sub.3 OCH.sub.3 H L-16aN N O CH.sub.3 OCH.sub.3 H L-16bN N O CH.sub.3 OCH.sub.3 H L-18aN N O CH.sub.3 OCH.sub.3 H L-20aN N O CH.sub.3 OCH.sub.3 H L-22aN N S CH.sub.3 OCH.sub.3 H L-1aN N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aN N O OCH.sub.3 OCH.sub.3 H L-1aN N O OCH.sub.3 OCH.sub.3 H L-1bN N O OCH.sub.3 OCH.sub.3 H L-1cN N O OCH.sub.3 OCH.sub.3 H L-1dN N O OCH.sub.3 OCH.sub.3 H L-1eN N O OCH.sub.3 OCH.sub.3 H L-1fN N O OCH.sub.3 OCH.sub.3 H L-1gN N O OCH.sub.3 OCH.sub.3 H L-1hN N O OCH.sub.3 OCH.sub.3 H L-1iN N O OCH.sub.3 OCH.sub.3 H L-3aN N O OCH.sub.3 OCH.sub.3 H L-3bN N O OCH.sub.3 OCH.sub.3 H L-4aN N O OCH.sub.3 OCH.sub.3 H L-7aN N O OCH.sub.3 OCH.sub.3 H L-8aN N O OCH.sub.3 OCH.sub.3 H L-8bN N O OCH.sub.3 OCH.sub.3 H L-9aN N O OCH.sub.3 OCH.sub.3 H L-12aN N O OCH.sub.3 OCH.sub.3 H L-12bN N O OCH.sub.3 OCH.sub.3 H L-14aN N O OCH.sub.3 OCH.sub.3 H L-15aN N O OCH.sub.3 OCH.sub.3 H L-16aN N O OCH.sub.3 OCH.sub.3 H L-16bN N O OCH.sub.3 OCH.sub.3 H L-18aN N O OCH.sub.3 OCH.sub.3 H L-20aN N O OCH.sub.3 OCH.sub.3 H L-22aN N S OCH.sub.3 OCH.sub.3 H L-1aN N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N O CH.sub.3 CH.sub.3 H L-1aCH N O CH.sub.3 CH.sub.3 H L-1bCH N O CH.sub.3 CH.sub.3 H L-1cCH N O CH.sub.3 CH.sub.3 H L-1dCH N O CH.sub.3 CH.sub.3 H L-1eCH N O CH.sub.3 CH.sub.3 H L-1fCH N O CH.sub.3 CH.sub.3 H L-1gCH N O CH.sub.3 CH.sub.3 H L-1hCH N O CH.sub.3 CH.sub.3 H L-1iCH N O CH.sub.3 CH.sub.3 H L-3aCH N O CH.sub.3 CH.sub.3 H L-3bCH N O CH.sub.3 CH.sub.3 H L-4aCH N O CH.sub.3 CH.sub.3 H L-7aCH N O CH.sub.3 CH.sub.3 H L-8aCH N O CH.sub.3 CH.sub.3 H L-8bCH N O CH.sub.3 CH.sub.3 H L-9aCH N O CH.sub.3 CH.sub.3 H L-12aCH N O CH.sub.3 CH.sub.3 H L-12bCH N O CH.sub.3 CH.sub.3 H L-14aCH N O CH.sub.3 CH.sub.3 H L-15aCH N O CH.sub.3 CH.sub.3 H L-16aCH N O CH.sub.3 CH.sub.3 H L-16bCH N O CH.sub.3 CH.sub.3 H L-18aCH N O CH.sub. 3 CH.sub.3 H L-20aCH N O CH.sub.3 CH.sub.3 H L-22aCH N S CH.sub.3 CH.sub.3 H L-1aCH N O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N O OCH.sub.3 CH.sub.3 H L-1aCH N O OCH.sub.3 CH.sub.3 H L-1bCH N O OCH.sub.3 CH.sub.3 H L-1cCH N O OCH.sub.3 CH.sub.3 H L-1dCH N O OCH.sub.3 CH.sub.3 H L-1eCH N O OCH.sub.3 CH.sub.3 H L-1fCH N O OCH.sub.3 CH.sub.3 H L-1gCH N O OCH.sub.3 CH.sub.3 H L-1hCH N O OCH.sub.3 CH.sub.3 H L-1iCH N O OCH.sub.3 CH.sub.3 H L-3aCH N O OCH.sub.3 CH.sub.3 H L-3bCH N O OCH.sub.3 CH.sub.3 H L-4aCH N O OCH.sub.3 CH.sub.3 H L-7aCH N O OCH.sub.3 CH.sub.3 H L-8aCH N O OCH.sub.3 CH.sub.3 H L-8bCH N O OCH.sub.3 CH.sub.3 H L-9aCH N O OCH.sub.3 CH.sub.3 H L-12aCH N O OCH.sub.3 CH.sub.3 H L-12bCH N O OCH.sub.3 CH.sub.3 H L-14aCH N O OCH.sub.3 CH.sub.3 H L-15aCH N O OCH.sub.3 CH.sub.3 H L-16aCH N O OCH.sub.3 CH.sub.3 H L-16bCH N O OCH.sub.3 CH.sub.3 H L-18aCH N O OCH.sub.3 CH.sub.3 H L-20aCH N O OCH.sub.3 CH.sub.3 H L-22aCH N S OCH.sub.3 CH.sub.3 H L-1aCH N O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N O CH.sub.3 OCH.sub.3 H L-1aCH N O CH.sub.3 OCH.sub.3 H L-1bCH N O CH.sub.3 OCH.sub.3 H L-1cCH N O CH.sub.3 OCH.sub.3 H L-1dCH N O CH.sub.3 OCH.sub.3 H L-1eCH N O CH.sub.3 OCH.sub.3 H L-1fCH N O CH.sub.3 OCH.sub.3 H L-1gCH N O CH.sub.3 OCH.sub.3 H L-1hCH N O CH.sub.3 OCH.sub.3 H L-1iCH N O CH.sub.3 OCH.sub.3 H L-3aCH N O CH.sub.3 OCH.sub.3 H L-3bCH N O CH.sub.3 OCH.sub.3 H L-4aCH N O CH.sub.3 OCH.sub.3 H L-7aCH N O CH.sub.3 OCH.sub. 3 H L-8aCH N O CH.sub.3 OCH.sub.3 H L-8bCH N O CH.sub.3 OCH.sub.3 H L-9aCH N O CH.sub.3 OCH.sub.3 H L-12aCH N O CH.sub.3 OCH.sub.3 H L-12bCH N O CH.sub.3 OCH.sub.3 H L-14aCH N O CH.sub.3 OCH.sub.3 H L-15aCH N O CH.sub.3 OCH.sub.3 H L-16aCH N O CH.sub.3 OCH.sub.3 H L-16bCH N O CH.sub.3 OCH.sub.3 H L-18aCH N O CH.sub.3 OCH.sub.3 H L-20aCH N O CH.sub.3 OCH.sub.3 H L-22aCH N S CH.sub.3 OCH.sub.3 H L-1aCH N O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N O OCH.sub.3 OCH.sub.3 H L-1aCH N O OCH.sub.3 OCH.sub.3 H L-1bCH N O OCH.sub.3 OCH.sub.3 H L-1cCH N O OCH.sub.3 OCH.sub.3 H L-1dCH N O OCH.sub.3 OCH.sub.3 H L-1eCH N O OCH.sub.3 OCH.sub.3 H L-1fCH N O OCH.sub.3 OCH.sub.3 H L-1gCH N O OCH.sub.3 OCH.sub.3 H L-1hCH N O OCH.sub.3 OCH.sub.3 H L-1iCH N O OCH.sub.3 OCH.sub.3 H L-3aCH N O OCH.sub.3 OCH.sub.3 H L-3bCH N O OCH.sub.3 OCH.sub.3 H L-4aCH N O OCH.sub.3 OCH.sub.3 H L-7aCH N O OCH.sub.3 OCH.sub.3 H L-8aCH N O OCH.sub.3 OCH.sub.3 H L-8bCH N O OCH.sub.3 OCH.sub.3 H L-9aCH N O OCH.sub.3 OCH.sub.3 H L-12aCH N O OCH.sub.3 OCH.sub.3 H L-12bCH N O OCH.sub.3 OCH.sub.3 H L-14aCH N O OCH.sub.3 OCH.sub.3 H L-15aCH N O OCH.sub.3 OCH.sub.3 H L-16aCH N O OCH.sub.3 OCH.sub.3 H L-16bCH N O OCH.sub.3 OCH.sub.3 H L-18aCH N O OCH.sub.3 OCH.sub.3 H L-20aCH N O OCH.sub.3 OCH.sub.3 H L-22aCH N S OCH.sub.3 OCH.sub.3 H L-1aCH N O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH O CH.sub.3 CH.sub.3 H L-1aCH CH O CH.sub.3 CH.sub.3 H L-1bCH CH O CH.sub.3 CH.sub.3 H L-1cCH CH O CH.sub.3 CH.sub.3 H L-1dCH CH O CH.sub.3 CH.sub.3 H L-1eCH CH O CH.sub.3 CH.sub.3 H L-1fCH CH O CH.sub.3 CH.sub.3 H L-1gCH CH O CH.sub.3 CH.sub.3 H L-1hCH CH O CH.sub.3 CH.sub.3 H L-1iCH CH O CH.sub.3 CH.sub.3 H L-3aCH CH O CH.sub.3 CH.sub.3 H L-3bCH CH O CH.sub.3 CH.sub.3 H L-4aCH CH O CH.sub.3 CH.sub.3 H L-7aCH CH O CH.sub.3 CH.sub.3 H L-8aCH CH O CH.sub.3 CH.sub.3 H L-8bCH CH O CH.sub.3 CH.sub.3 H L-9aCH CH O CH.sub.3 CH.sub.3 H L-12aCH CH O CH.sub.3 CH.sub.3 H L-12bCH CH O CH.sub.3 CH.sub.3 H L-14aCH CH O CH.sub.3 CH.sub.3 H L-15aCH CH O CH.sub.3 CH.sub.3 H L-16aCH CH O CH.sub.3 CH.sub.3 H L-16bCH CH O CH.sub.3 CH.sub.3 H L-18aCH CH O CH.sub.3 CH.sub.3 H L-20aCH CH O CH.sub.3 CH.sub.3 H L-22aCH CH S CH.sub.3 CH.sub.3 H L-1aCH CH O CH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH O OCH.sub.3 CH.sub.3 H L-1aCH CH O OCH.sub.3 CH.sub.3 H L-1bCH CH O OCH.sub.3 CH.sub.3 H L-1cCH CH O OCH.sub.3 CH.sub.3 H L-1dCH CH O OCH.sub.3 CH.sub.3 H L-1eCH CH O OCH.sub.3 CH.sub.3 H L-1fCH CH O OCH.sub.3 CH.sub.3 H L-1gCH CH O OCH.sub.3 CH.sub.3 H L-1hCH CH O OCH.sub.3 CH.sub.3 H L-1iCH CH O OCH.sub.3 CH.sub.3 H L-3aCH CH O OCH.sub.3 CH.sub.3 H L-3bCH CH O OCH.sub.3 CH.sub.3 H L-4aCH CH O OCH.sub.3 CH.sub.3 H L-7aCH CH O OCH.sub.3 CH.sub.3 H L-8aCH CH O OCH.sub.3 CH.sub.3 H L-8bCH CH O OCH.sub.3 CH.sub.3 H L-9aCH CH O OCH.sub.3 CH.sub.3 H L-12aCH CH O OCH.sub.3 CH.sub.3 H L-12bCH CH O OCH.sub.3 CH.sub.3 H L-14aCH CH O OCH.sub.3 CH.sub.3 H L-15aCH CH O OCH.sub.3 CH.sub.3 H L-16aCH CH O OCH.sub.3 CH.sub.3 H L-16bCH CH O OCH.sub.3 CH.sub.3 H L-18aCH CH O OCH.sub.3 CH.sub.3 H L-20aCH CH O OCH.sub.3 CH.sub.3 H L-22aCH CH S OCH.sub.3 CH.sub.3 H L-1aCH CH O OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH CH O CH.sub.3 OCH.sub.3 H L-1aCH CH O CH.sub.3 OCH.sub.3 H L-1bCH CH O CH.sub.3 OCH.sub.3 H L-1cCH CH O CH.sub.3 OCH.sub.3 H L-1dCH CH O CH.sub.3 OCH.sub.3 H L-1eCH CH O CH.sub.3 OCH.sub.3 H L-1fCH CH O CH.sub.3 OCH.sub.3 H L-1gCH CH O CH.sub.3 OCH.sub.3 H L-1hCH CH O CH.sub.3 OCH.sub.3 H L-1iCH CH O CH.sub.3 OCH.sub.3 H L-3aCH CH O CH.sub.3 OCH.sub.3 H L-3bCH CH O CH.sub.3 OCH.sub.3 H L-4aCH CH O CH.sub.3 OCH.sub.3 H L-7aCH CH O CH.sub.3 OCH.sub.3 H L-8aCH CH O CH.sub.3 OCH.sub.3 H L-8bCH CH O CH.sub.3 OCH.sub.3 H L-9aCH CH O CH.sub.3 OCH.sub.3 H L-12aCH CH O CH.sub.3 OCH.sub.3 H L-12bCH CH O CH.sub.3 OCH.sub.3 H L-14aCH CH O CH.sub.3 OCH.sub.3 H L-15aCH CH O CH.sub.3 OCH.sub.3 H L-16aCH CH O CH.sub.3 OCH.sub.3 H L-16bCH CH O CH.sub.3 OCH.sub.3 H L-18aCH CH O CH.sub.3 OCH.sub.3 H L-20aCH CH O CH.sub.3 OCH.sub.3 H L-22aCH CH S CH.sub.3 OCH.sub.3 H L-1aCH CH O CH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH CH O OCH.sub.3 OCH.sub.3 H L-1aCH CH O OCH.sub.3 OCH.sub.3 H L-1bCH CH O OCH.sub.3 OCH.sub.3 H L-1cCH CH O OCH.sub.3 OCH.sub.3 H L-1dCH CH O OCH.sub.3 OCH.sub.3 H L-1eCH CH O OCH.sub.3 OCH.sub.3 H L-1fCH CH O OCH.sub.3 OCH.sub.3 H L-1gCH CH O OCH.sub.3 OCH.sub.3 H L-1hCH CH O OCH.sub.3 OCH.sub.3 H L-1iCH CH O OCH.sub.3 OCH.sub.3 H L-3aCH CH O OCH.sub.3 OCH.sub.3 H L-3bCH CH O OCH.sub. 3 OCH.sub.3 H L-4aCH CH O OCH.sub.3 OCH.sub.3 H L-7aCH CH O OCH.sub.3 OCH.sub.3 H L-8aCH CH O OCH.sub.3 OCH.sub.3 H L-8bCH CH O OCH.sub.3 OCH.sub.3 H L-9aCH CH O OCH.sub.3 OCH.sub.3 H L-12aCH CH O OCH.sub.3 OCH.sub.3 H L-12bCH CH O OCH.sub.3 OCH.sub.3 H L-14aCH CH O OCH.sub.3 OCH.sub.3 H L-15aCH CH O OCH.sub.3 OCH.sub.3 H L-16aCH CH O OCH.sub.3 OCH.sub.3 H L-16bCH CH O OCH.sub.3 OCH.sub.3 H L-18aCH CH O OCH.sub.3 OCH.sub.3 H L-20aCH CH O OCH.sub.3 OCH.sub.3 H L-22aCH CH S OCH.sub.3 OCH.sub.3 H L-1aCH CH O OCH.sub.3 OCH.sub.3 CH.sub.3 L-1a______________________________________
TABLE 16______________________________________General Formula 16Z.sub.1 Z.sub.2 Y W R L m.p. (.degree.C.)______________________________________CH CH CH.sub.3 O H L-1aCH N CH.sub.3 O H L-1aN CH CH.sub.3 O H L-1aN N CH.sub.3 O H L-1aCH CH OCH.sub.3 O H L-1aCH N OCH.sub.3 O H L-1aN CH OCH.sub.3 O H L-1aN N OCH.sub.3 O H L-1a______________________________________
TABLE 17______________________________________General Formula 17Z.sub.1 Z.sub.2 X W R L m.p. (.degree.C.)______________________________________CH CH CH.sub.3 O H L-1aCH N CH.sub.3 O H L-1aN CH CH.sub.3 O H L-1aN N CH.sub.3 O H L-1aCH CH OCH.sub.3 O H L-1aCH N OCH.sub.3 O H L-1aN CH OCH.sub.3 O H L-1aN N OCH.sub.3 O H L-1a______________________________________
TABLE 18______________________________________General Formula 18Z Z.sub.1 Z.sub.2 G X Y L m.p. (.degree.C.)______________________________________CH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1bCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1cCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1dCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1eCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1fCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1gCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1hCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-1iCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-3aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-3bCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-4aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-7aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-8aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-8bCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-9aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-12aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-12bCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-14aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-15aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-16aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-16bCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-18aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-20aCH N CH OCH.sub.3 CH.sub.3 CH.sub.3 L-22aCH N CH SCH.sub.3 CH.sub.3 CH.sub.3 L-1aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1bCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1cCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1dCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1eCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1fCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1gCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1hCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-1iCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-3aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-3bCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-4aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-7aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-8aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-8bCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-9aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-12aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-12bCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-14aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-15aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-16aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-16bCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-18aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-20aCH N CH OCH.sub.3 OCH.sub.3 CH.sub.3 L-22aCH N CH SCH.sub.3 OCH.sub.3 CH.sub.3 L-1aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1bCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1cCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1dCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1eCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1fCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1gCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1hCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-1iCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-3aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-3bCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-4aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-7aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-8aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-8bCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-9aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-12aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-12bCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-14aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-15aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-16aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-16bCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-18aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-20aCH N CH OCH.sub.3 CH.sub.3 OCH.sub.3 L-22aCH N CH SCH.sub.3 CH.sub.3 OCH.sub.3 L-1aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1bCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1cCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1dCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1eCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1fCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1gCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1hCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-1iCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-3aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-3bCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-4aCH N CH OCH.sub.3 CCH.sub.3 OCH.sub.3 L-7aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-8aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-8bCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-9aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-12aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-12bCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-14aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-15aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-16aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-16bCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-18aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-20aCH N CH OCH.sub.3 OCH.sub.3 OCH.sub.3 L-22aCH N CH SCH.sub.3 OCH.sub.3 OCH.sub.3 L-1a______________________________________
TABLE 19______________________________________General Formula 19Z Z.sub.1 Z.sub.2 W X Y L m.p. (.degree.C.)______________________________________CH N N O CH.sub.3 CH.sub.3 L-1a 227-229CH N N O CH.sub.3 CH.sub.3 L-1b 207-209CH N N O CH.sub.3 CH.sub.3 L-1c 194-196CH N N O CH.sub.3 CH.sub.3 L-1d 244-246CH N N O CH.sub.3 CH.sub.3 L-1eCH N N O CH.sub.3 CH.sub.3 L-1fCH N N O CH.sub.3 CH.sub.3 L-1gCH N N O CH.sub.3 CH.sub.3 L-1hCH N N O CH.sub.3 CH.sub.3 L-1iCH N N O CH.sub.3 CH.sub.3 L-1jCH N N O CH.sub.3 CH.sub.3 L-1kCH N N O CH.sub.3 CH.sub.3 L-1l 303-306CH N N O CH.sub.3 CH.sub.3 L-1mCH N N O CH.sub.3 CH.sub.3 L-1nCH N N O CH.sub.3 CH.sub.3 L-1oCH N N O CH.sub.3 CH.sub.3 L-1p 282-284CH N N O CH.sub.3 CH.sub. 3 L-1qCH N N O CH.sub.3 CH.sub.3 L-1rCH N N O CH.sub.3 CH.sub.3 L-1sCH N N O CH.sub.3 CH.sub.3 L-1tCH N N O CH.sub.3 CH.sub.3 L-1uCH N N O CH.sub.3 CH.sub.3 L-1vCH N N O CH.sub.3 CH.sub.3 L-3aCH N N O CH.sub.3 CH.sub.3 L-3bCH N N O CH.sub.3 CH.sub.3 L-4aCH N N O CH.sub.3 CH.sub.3 L-7aCH N N O CH.sub.3 CH.sub.3 L-8aCH N N O CH.sub.3 CH.sub.3 L-8bCH N N O CH.sub.3 CH.sub.3 L-9aCH N N O CH.sub.3 CH.sub.3 L-10aCH N N O CH.sub.3 CH.sub.3 L-12aCH N N O CH.sub.3 CH.sub.3 L-12bCH N N O CH.sub.3 CH.sub.3 L-12cCH N N O CH.sub.3 CH.sub.3 L-14aCH N N O CH.sub.3 CH.sub.3 L-15aCH N N O CH.sub.3 CH.sub.3 L-16aCH N N O CH.sub.3 CH.sub.3 L-16bCH N N O CH.sub.3 CH.sub.3 L-18aCH N N O CH.sub.3 CH.sub.3 L-20aCH N N O CH.sub.3 CH.sub.3 L-20bCH N N O CH.sub.3 CH.sub.3 L-22aCH N CH O CH.sub.3 CH.sub.3 L-1aCH N CH O CH.sub.3 CH.sub.3 L-1bCH N CH O CH.sub.3 CH.sub.3 L-1cCH N CH O CH.sub.3 CH.sub.3 L-1dCH N CH O CH.sub.3 CH.sub.3 L-1eCH N CH O CH.sub.3 CH.sub.3 L-1fCH N CH O CH.sub.3 CH.sub.3 L-1gCH N CH O CH.sub.3 CH.sub.3 L-1hCH N CH O CH.sub.3 CH.sub.3 L-1iCH N CH O CH.sub.3 CH.sub.3 L-1jCH N CH O CH.sub.3 CH.sub.3 L-1kCH N CH O CH.sub.3 CH.sub.3 L-1lCH N CH O CH.sub.3 CH.sub.3 L-1mCH N CH O CH.sub.3 CH.sub.3 L-1nCH N CH O CH.sub.3 CH.sub.3 L-1oCH N CH O CH.sub.3 CH.sub.3 L-1pCH N CH O CH.sub.3 CH.sub.3 L-1qCH N CH O CH.sub.3 CH.sub.3 L-1rCH N CH O CH.sub.3 CH.sub.3 L-1sCH N CH O CH.sub.3 CH.sub.3 L-1tCH N CH O CH.sub.3 CH.sub.3 L-1uCH N CH O CH.sub.3 CH.sub.3 L-1vCH N CH O CH.sub.3 CH.sub.3 L-3aCH N CH O CH.sub.3 CH.sub.3 L-3bCH N CH O CH.sub.3 CH.sub.3 L-4aCH N CH O CH.sub.3 CH.sub.3 L-7aCH N CH O CH.sub.3 CH.sub.3 L-8aCH N CH O CH.sub.3 CH.sub.3 L-8bCH N CH O CH.sub.3 CH.sub.3 L-9aCH N CH O CH.sub.3 CH.sub.3 L-10aCH N CH O CH.sub.3 CH.sub.3 L-12aCH N CH O CH.sub.3 CH.sub.3 L-12bCH N CH O CH.sub.3 CH.sub.3 L-12cCH N CH O CH.sub.3 CH.sub.3 L-14aCH N CH O CH.sub.3 CH.sub.3 L-15aCH N CH O CH.sub.3 CH.sub.3 L-16aCH N CH O CH.sub.3 CH.sub.3 L-16bCH N CH O CH.sub.3 CH.sub.3 L-18aCH N CH O CH.sub.3 CH.sub.3 L-20aCH N CH O CH.sub.3 CH.sub.3 L-20bCH N CH O CH.sub.3 CH.sub.3 L-22aCH CH N O CH.sub.3 CH.sub.3 L-1aCH CH N O CH.sub.3 CH.sub.3 L-1bCH CH N O CH.sub.3 CH.sub.3 L-1cCH CH N O CH.sub.3 CH.sub.3 L-1dCH CH N O CH.sub.3 CH.sub.3 L-1eCH CH N O CH.sub.3 CH.sub.3 L-1fCH CH N O CH.sub.3 CH.sub.3 L-1gCH CH N O CH.sub.3 CH.sub.3 L-1hCH CH N O CH.sub.3 CH.sub.3 L-1iCH CH N O CH.sub.3 CH.sub.3 L-1jCH CH N O CH.sub.3 CH.sub.3 L-1kCH CH N O CH.sub.3 CH.sub.3 L-1lCH CH N O CH.sub.3 CH.sub.3 L-1mCH CH N O CH.sub.3 CH.sub.3 L-1nCH CH N O CH.sub.3 CH.sub.3 L-1oCH CH N O CH.sub.3 CH.sub.3 L-1pCH CH N O CH.sub.3 CH.sub.3 L-1qCH CH N O CH.sub.3 CH.sub.3 L-1rCH CH N O CH.sub.3 CH.sub.3 L-1sCH CH N O CH.sub.3 CH.sub.3 L-1tCH CH N O CH.sub.3 CH.sub.3 L-1uCH CH N O CH.sub.3 CH.sub.3 L-1vCH CH N O CH.sub.3 CH.sub.3 L-3aCH CH N O CH.sub.3 CH.sub.3 L-3bCH CH N O CH.sub.3 CH.sub.3 L-4aCH CH N O CH.sub.3 CH.sub.3 L-7aCH CH N O CH.sub.3 CH.sub.3 L-8aCH CH N O CH.sub.3 CH.sub.3 L-8bCH CH N O CH.sub.3 CH.sub.3 L-9aCH CH N O CH.sub.3 CH.sub.3 L-10aCH CH N O CH.sub.3 CH.sub.3 L-12aCH CH N O CH.sub.3 CH.sub.3 L-12bCH CH N O CH.sub.3 CH.sub.3 L-12cCH CH N O CH.sub.3 CH.sub.3 L-14aCH CH N O CH.sub.3 CH.sub.3 L-15aCH CH N O CH.sub.3 CH.sub.3 L-16aCH CH N O CH.sub.3 CH.sub.3 L-16bCH CH N O CH.sub.3 CH.sub.3 L-18aCH CH N O CH.sub.3 CH.sub.3 L-20aCH CH N O CH.sub.3 CH.sub.3 L-20bCH CH N O CH.sub.3 CH.sub.3 L-22a______________________________________
Formulations
Useful formulations of the compounds of Formulae Ia and Ib can be prepared in conventional ways. They include dusts, granules, pellets, solutions, suspensions, emulsions, wettable powders, emulsifiable concentrates and the like. Many of these may be applied directly. Sprayable formulations can be extended in suitable media and used at spray volumes of from a few liters to several hundred liters per hectare. High strength compositions are primarily used as intermediates for further formulation. The formulations, broadly, contain about 0.1% to 99% by weight of active ingredient(s) and at least one of (a) about 0.1% to 20% surfactant(s) and (b) about 1% to 99.9% solid or liquid diluent(s). More specifically, they will contain these ingredients in the following approximate proportions:
TABLE 20______________________________________ Weight Percent* Active Ingredient Diluent(s) Surfactant(s)______________________________________Wettable Powders 20-90 0-74 1-10Oil Suspensions, 3-50 40-95 0-15Emulsions, Solutions,(including EmulsifiableConcentrates)Aqueous Suspension 10-50 40-84 1-20Dusts 1-25 70-99 0-5Granules and Pellets 0.1-95 5-99.9 0-15High Strength 90-99 0-10 0-2Compositions______________________________________ *Active ingredient plus at least one of a Surfactant or a Diluent equals 100 weight percent.
Lower or higher levels of active ingredient can, of course, be present depending on the intended use and the physical properties of the compound. Higher ratios of surfactant to active ingredient are sometimes desirable, and are achieved by incorporation into the formulation or by tank mixing.
Typical solid diluents are described in Watkins, et al., "Handbook of Insecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books, Caldwell, N.J., but other solids, either mined or manufactured, may be used. The more absorptive diluents are preferred for wettable powders and the denser ones for dusts. Typical liquid diluents and solvents are described in Marsden, "Solvents Guide," 2nd Ed., Interscience, New York, 1950. Solubility under 0.1% is preferred for suspension concentrates; solution concentrates are preferably stable against phase separation at 0.degree. C. "McCutcheon's Detergents and Emulsifiers Annual", MC Publishing Corp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia of Surface Active Agents", Chemical Publishing Co., Inc., New York, 1964, list surfactants and recommended uses. All formulations can contain minor amounts of additives to reduce foaming, caking, corrosion, microbiological growth, etc.
The methods of making such compositions are well known. Solutions are prepared by simply mixing the ingredients. Fine solids compositions are made by blending and, usually, grinding as in a hammer or fluid energy mill. Suspensions are prepared by wet milling (see, for example, Littler, U.S. Pat. No. 3,060,084). Granules and pellets may be made by spraying the active material upon preformed granular carriers or by agglomeration techniques. See J. E. Browning, "Agglomeration", Chemical Engineering, Dec. 4, 1967, pp. 147ff. and "Perry's Chemical Engineer's Handbook", 5th Ed., McGraw-Hill, New York, 1973, pp. 8-57 ff.
For further information regarding the art of formulation, see for example:
H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16 through Col. 7, line 19 and Examples 10 through 41;
R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line 43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58, 132, 138-140, 162-164, 166, 167 and 169-182;
H. Gysin and E. Knusli, U.S. Pat. No. 2,891,855, June 23, 1959, Col. 3, line 66 through Col. 5, line 17 and Examples 1-4;
G. C. Klingman, "Weed Control as a Science", John Wiley and Sons, Inc., New York, 1961, pp. 81-96; and
J. D. Fryer and S. A. Evans, "Weed Control Handbook", 5th Ed., Blackwell Scientific Publications, Oxford, 1968, pp. 101-103.
In the following examples, all parts are by weight unless otherwise indicated.
EXAMPLE 19
______________________________________Wettable powder______________________________________Methyl 2-[[[(5,7-dimethylpyrazolo[1,5-A]pyrimidin-3-yl)- 80%carbonyl]amino]sulfonyl]benzoatesodium alkylnaphthalenesulfonate 2%sodium ligninsulfonate 2%synthetic amorphous silica 3%kaolinite 13%______________________________________
The ingredients are blended, hammer-milled until all the solids are essentially under 50 microns, reblended, and packaged.
EXAMPLE 20
______________________________________Wettable Powder______________________________________Methyl 2-[[[(5,7-dimethyl[1,2,3]triazolo[1,5-A]- 50%pyrimidin-3-yl)cabonyl]amino]sulfonyl]benzoatesodium alknaphthalenesulfonate 2%low viscosity methyl cellulose 2%diatomaceous earth 46%______________________________________
The ingredients are blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in diameter. The product is reblended before packaging.
EXAMPLE 21
______________________________________Granule______________________________________Wettable Powder of Example 20 5%attapulgite granules 95%(U.S.S. 20-40 mesh; 0.84-0.42 mm)______________________________________
A slurry of wettable powder containing 25% solids is sprayed on the surface of attapulgite granules in a double-cone blender. The granules are dried and packaged.
EXAMPLE 22
______________________________________Extruded Pellet______________________________________5,7-Dimethyl-N--[[2-(methylsulfonyl)phenyl]sulfonyl]- 25%pyrazolo[1,5-A]pyrimidine-3-carboxamideanhydrous sodium sulfate 10%crude calcium ligninsulfonate 5%sodium alklnaphthalenesulfonate 1%calcium/magnesium bentonite 59%______________________________________
The ingredients are blended, hammer-milled and then moistened with about 12% water. The mixture is extruded as cylinders about 3 mm diameter which are cut to produce pellets about 3 mm long. These may be used directly after drying, or the dried pellets may be crushed to pass a U.S.S. No. 20 sieve (0.84 mm openings). The granules held on a U.S.S. No. 40 sieve (0.42 mm openings) may be packaged for use and the fines recycled.
EXAMPLE 23
______________________________________Oil Suspension______________________________________N--8 [2-(1-ethyl-1H-tetrazol-5-yl)phenyl]sulfonyl]-5,7- 25%dimethylpyrazolo[1,5-A]pyrimidine-3-carbamatepolyoxyethylene sorbitol hexaoleate 5%highly aliphatic hydrocarbon oil 70%______________________________________
The ingredients are ground together in a sand mill until the solid particles have been reduced to under about 5 microns. The resulting thick suspension may be applied directly, but preferably after being extended with oils or emulsified in water.
EXAMPLE 24
______________________________________Wettable Powder______________________________________5,7-Dimethyl-N--[[2-(methylsulfonyl)phenyl]sulfonyl]- 20%pyrazolo[1,5-A]pyrimidine-3-carboxamidesodium alkylnaphthalenesulfonate 4%sodium ligninsulfonate 4%low viscosity methyl cellulose 3%attapulgite 69%______________________________________
The ingredients are thoroughly blended. After grinding in a hammer-mill to produce particles essentially all below 100 microns, the material is reblended and sifted through a U.S.S. No. 50 sieve (0.3 mm opening) and packaged.
EXAMPLE 25
______________________________________Low Strength Granule______________________________________Methyl 2-[[[(5,7-dimethylpyrazolo[1,5-A]pyrimidin- 1%3-yl)carbonyl]amino]sulfonyl]benzoateN,N--dimethylforamide 9%attapulgite granules 90%U.S.S. 20-40 sieve)______________________________________
The active ingredient is dissolved in the solvent and the solution is sprayed upon dedusted granules in a double cone blender. After spraying of the solution has been completed, the blender is allowed to run for a short period and then the granules are packaged.
EXAMPLE 26
______________________________________Aqueous Suspension______________________________________Methyl 2-[[[(5,7-dimethyl[1,2,3]triazolo[1,5-A]- 40%pyrimidin-3-yl)carbonyl]amino]sulfonyl]benzoatepolyacrylic acid thickener 0.3%dodecylphenol polyethylene glycol ether 0.5%disodium phosphate 1%monosodium phosphate 0.5%polyvinyl alcohol 1.0%water 56.7%______________________________________
The ingredients are blended and ground together in a sand mill to produce particles essentially all under 5 microns in size.
EXAMPLE 27
______________________________________Solution______________________________________N--[[2-(1-ethyl-1H--tetrazol-5-yl)phenyl]sulfonyl]-5,7- 5%dimethylpyrazolo[1,5-A]pyrimidine-3-carbamatewater 95%______________________________________
The salt is added directly to the water with stirring to produce the solution, which may then be packaged for use.
EXAMPLE 28
______________________________________Low Strength Granule______________________________________5,7-Dimethyl-N--[[2-(methylsulfonyl)phenyl]sulfonyl]-pyrazolo[1,5-A]pyrimidine-3-carboxamide 0.1%attapulgite granule 99.9%(U.S.S. 20-40 mesh)______________________________________
The active ingredient is dissolved in a solvent and the solution is sprayed upon dedusted granules in a double-cone blender. After spraying of the solution has been completed, the material is warmed to evaporate the solvent. The material is allowed to cool and then packaged.
EXAMPLE 29
______________________________________Granule______________________________________Methyl 2-[[[(5,7-dimethylpyrazolo[1,5- 80%A]pyrimidin-3-yl)carbonyl]amino]sulfonyl]-benzoatewetting agent 1%crude ligninsulfonate salt (containing 10%5-20% of the natural sugars)attapulgite clay 9%______________________________________
The ingredients are blended and milled to pass through a 100 mesh screen. This material is then added to a fluid bed granulator, the air flow is adjusted to gently fluidize the material, and a fine spray of water is sprayed onto the fluidized material. The fluidization and spraying are continued until granules of the desired size range are made. The spraying is stopped, but fluidization is continued, optionally with heat, until the water content is reduced to the desired level, generally less than 1%. The material is then discharged, screened to the desired size range, generally 14-100 mesh (1410-149 microns), and packaged for use.
EXAMPLE 30
______________________________________High Strength Concentrate______________________________________Methyl 99%2-[[[(5,7-dimethly[1,2,3]triazolo[1,5-A]pyrimidin-3-yl)- 99%carbonyl]amino]sulfonyl]benzoatesilica aerogel 0.5%synthetic amorphous silica 0.5%______________________________________
The ingredients are blended and ground in a hammer-mill to produce a material essentially all passing a U.S.S. No. 50 screen (0.3 mm opening). The concentrate may be formulated further if necessary.
EXAMPLE 31
______________________________________Wettable Powder______________________________________5,7-Dimethyl-N--[[2-(methylsulfonyl)phenyl]sulfonyl]- 90%pyrazolo[1,5-A]pyrimidine-3-carboxamidedioctyl sodium sulfosuccinate 0.1%synthetic fine silica 9.9%______________________________________
The ingredients are blended and ground in a hammer-mill to produce particles essentially all below 100 microns. The material is sifted through a U.S.S. No. 50 screen and then packaged.
EXAMPLE 32
______________________________________Wettable Powder______________________________________Methyl 40%2-[[[(5,7-dimethylpyrazolo[1,5-A]pyrimidin-3-yl)-carbonyl]amino]sulfonyl]benzoatesodium ligninsulfonate 20%montmorillonite clay 40%______________________________________
The ingredients are thoroughly blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in size. The material is reblended and then packaged.
EXAMPLE 33
______________________________________Oil Suspension______________________________________N--[[2-(ethyl-1H--tetrazol-5-yl)phenyl]sulfonyl]-5,7- 35%dimethylpyrazolo[1,5-A]pyrimidine-3-carbamateblend of polyalcohol carboxylic 6%esters and oil soluble petroleumsulfonatesxylene 59%______________________________________
The ingredients are combined and ground together in a sand mill to produce particles essentially all below 5 microns. The product can be used directly, extended with oils, or emulsified in water.
EXAMPLE 34
______________________________________Dusts______________________________________Methyl 2-[[[(5,7-dimethyl[1,2,3]triazolo[1,5-A]- 10%pyrimidin-3-yl)carbonyl]amino]sulfonyl]benzoateattapulgite 10%Pyrophyllite 80%______________________________________
The active ingredient is blended with attapulgite and then passed through a hammer-mill to produce particles substantially all below 200 microns. The ground concentrate is then blended with powdered pyrophyllite until homogeneous.
EXAMPLE 35
______________________________________Emilsifiable Concentrate______________________________________5,7-Dimethyl-N--[[2-(methylsulfonyl)phenyl]sulfonyl]- 10%pyrazolo[1,5-A]pyrimidine-3-carboxamidechlorobenzene 84%sorbitan monostearate and polyoxyethylene 6%condensates thereof______________________________________
The ingredients are combined and stirred to produce a solution which can be emulsified in water for application.
Utility
Test results indicate that the compounds of the present invention are highly active preemergent or postemergent herbicides or plant growth regulants. Many of them have utility for broad-spectrum pre- and/or postemergence weed control in areas where complete control of all vegetation is desired, such as around fuel storage tanks, ammunition depots, industrial storage areas, parking lots, drive-in theaters, around billboards, highway and railroad structures. Some of the compounds have utility for selective weed control in crops such as rice, wheat, barley, corn, soybeans, sugarbeets and cotton. Alternatively, the subject compounds are useful to modify plant growth.
The rates of application for the compounds of the invention are determined by a number of factors, including their use as plant growth modifiers or as herbicides, the crop species involved, the types of weeds to be controlled, weather and climate, formulations selected, mode of application, amount of foliage present, etc. In general terms, the subject compounds should be applied at levels of around 0.010 to 20 kg/ha, the lower rates being suggested for use on lighter soils and/or those having a low organic matter content, for plant growth modification or for situations where only short-term persistence is required, such as a herbicide for fallow land.
The compounds of the invention may be used in combination with any other commercial herbicide, non-limiting examples of which are those of the sulfonylurea, triazine, triazole, uracil, urea, amide, diphenyl ether, carbamate, imidazolinone, cineole and bipyridylium types.
The herbicidal properties of the subject compounds were discovered in a number of greenhouse tests. The test procedures and results follow.
It is noted that several of the compounds exhibit little herbicidal activity at the rates tested; it is believed that these compounds would have activity at application rates not exceeding 20 kg/ha. ##STR130##
Test A
Seeds of crabgrass (Digitaria spp.), barnyard-grass (Echinochloa crus-galli), giant foxtail (Setaria faberii), wild oats (Avena fatua), cheatgrass (Bromus secalinus), velvetleaf (Abutilon theophrasti), morningglory (Ipomoea spp.), cocklebur (Xanthium pensylvanicum), sorghum, corn, soybean, sugarbeet, cotton, rice, wheat, barley and purple nutsedge (Cyperus rotundus) tubers were planted and treated preemergence with the test chemicals dissolved in a non-phytotoxic solvent. At the same time, these crop and weed species were treated with a soil/foilage application. At the time of treatment, the plants ranged in height from 2 to 18 cm. Treated plants and controls were maintained in a greenhouse for sixteen days, after which all species were compared to controls and visually rated for response to treatment. The ratings, summarized in Table A, are based on a numerical scale extending from 0=no injury, to 10=complete kill. The accompanying descriptive symbols have the following meanings:
C=chlorosis/necrosis;
B=burn;
D=defoliation;
E=emergence inhibition;
G=growth retardation;
H=formative effect;
U=unusual pigmentation;
X=axillary stimulation;
S=albinism; and
Y=abscised buds or flowers.
TABLE A__________________________________________________________________________ CMPD 1 CMPD 2 CMPD 3 CMPD 4 CMPD 5 CMPD 6 CMPD 7 CMPD 8RATE RATE = KG/HA 0.4 0.4 0.4 0.4 0.4 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 10C 6C,9G 4C,9G 10C 10C 9C 5G 9C 5C,9G 10CMORNING GLORY 2C,6G 10C 0 10C 10C 10C 9C 10C 10C 10CCOCKLEBUR 4C,9H 10C 5H 9C 10C 10C 10C 9C 10C 10CNUTSEDGE 5C,9G 5C,9G 8G 2C,9G 2C,9G 5C,9G 5C,9G 9C 4C,9G 5C,9GCRABGRASS 4C,9H 4C,9G 0 5G 9G 2C,8G 3C,6G 5C,9G 3C,7G 4C,9GBARNYARD GRASS 5C,9H 9C 2C,9G 9C 9C 10C 9C 10C 10C 10CWILD OATS 5C,9G 5C,9G 0 0 5C,9G 9C 9C 9C 2C,8G 3C,8GWHEAT 2C,9G 5C,9G 1G 8G 9G 9C 9C 9C 9C 10CCORN 9G 9C 0 5C,9G 5C,9G 10C 10C 10C 9C 9CSOYBEAN 4C,9G 9C 1H 4C,9G 6C,9G 5C,9G 9C 9C 9C 9CRICE 6C,9G 9C 9G 5C,9G 9C 9C 9C 9C 9C 9CSORGHUM 2C,9G 9C 2C,9G 9G 9C 9C 10C 9C 10C 9CCHEATGRASS 9G 9C 2G 6G 9C 10C 9C 9C 10C 10CSUGAR BEETS 4C,9G 5C,9G 5C,9G 10C 9C 9C 4C,9G 10C 9C 10CVELVETLEAF 10C 10C 9C 10C 10C 10C 2H,7G 9C 10C 10CGIANT FOXTAIL 6G 4C,9G 1H 2C,8G 9C 5C,9G 9C 10C 5C,9G 9CBARLEY 9G 4C,9G 0 5G 6C,9G 6C,9G 9C 9C 9C 9C PREEMERGENCECOTTON 8G 9G 0 8G 8G 2C,9G 0 1C 2G 8GMORNING GLORY 5G 9H 0 4G 8G 8H 0 0 2C,4G 9GCOCKLEBUR 9H 9H 1C 2C,4H 8H 9H 0 1C 3C,3H 9HNUTSEDGE 7G 10E 10E 3C.9G 10E 10E 0 0 7G 10ECRABGRASS 7G 2C,8G 0 3G 8H 3C,9G 0 0 5G 2C,8GBARNYARD GRASS 9H 9H 5G 9H 9H 9H 0 2C 3G 9HWILD OATS 2C,8H 3C,9H 2G 4G 3C,9H 4C,5H 0 2C 2C,4G 3C,8GWHEAT 4C,9G 3C,9H 7G 2C,9H 3C,9H 2C,9H 0 0 8H 9HCORN 6C,9H 2C,9H 0 9H 3C,9G 9G 0 2C,9H 3C,8H 5C,9GSOYBEAN 2C,8H 9H 2C,2H 6H 8H 9H 2G 3C,4H 3C,6G 9HRICE 4C,9H 10E 7H 10E 10E 10E 3G 3C,9G 9H 10ESORGHUM 9H 10H 9H 5C,9H 5C,9H 5C,9G 1C 3C,9G 9H 10HCHEATGRASS 9G 9H 6G 7G 9H 9H 0 8G 8G 9HSUGAR BEETS 7G 9G 8H 9G 9G 5C,9G 0 0 7G 9GVELVETLEAF 8H 5C,9G 2H 7H 5H 6C,9G 0 2G 5G 8HGIANT FOXTAIL 6G 3C,9G 0 3C,8H 9H 3C,9H 0 0 2G 9HBARLEY 2C,9G 4C,9H 3G 5G 9G 9G 0 1C 8G 3C,9G__________________________________________________________________________ CMPD 9 CMPD 10 CMPD 11 CMPD 12 CMPD 13RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 4C,9G 5C,9G 5C,9G 5C,9G 9C 9C 9H 5C,9G 8G 10CMORNING GLORY 6G 9C 10C 10C 10C 10C 3C,8H 5C,9G 9C 10CCOCKLEBUR 4C,9H 10C 10C 10C 10C 10C 4C,9G 10C 9C 10CNUTSEDGE 3C,9G 9G 6C,9G 5C,9G 4C,9G 5C,9G 9G 4C,9G 9C 9CCRABGRASS 2G 5G 2C,6G 8H 3C,8G 9C 1H 3C,8G 8G 9CBARNYARD GRASS 7H 10C 10C 10C 10C 10C 3C,7H 9C 10C 10CWILD OATS 2G 5G 5C,9G 9C 3C,7G 4C,9G 2C,4G 3C,6G 6C,9G 9CWHEAT 8G 2C,9G 3C,9G 9C 5C,9G 9C 2C,9G 9G 6C,9G 9CCORN 2C,6G 3C,9H 2C,8H 3C,8H 9C 9C 5C,9G 5C,9G 10C 10CSOYBEAN 3C,7H 3C,9G 3C,9G 9C 9C 9C 3C,8H 3C,9G 9C 9CRICE 5C,9G 9C 9C 9C 9C 9C 9C 9C 9C 9CSORGHUM 3C,7H 4C,9G 9C 10C 10C 9C 5C,9G 9C 10C 10CCHEATGRASS 9G 4C,9G 0 3G 9C 9C 9C 9C 10C 10CSUGAR BEETS 0 2G 1C 5C,7G 10C 10C 0 1H 9C 10CVELVETLEAF 5C,9H 10C 10C 10C 10C 10C 9C 10C 5C,9G 10CGIANT FOXTAIL 2C,6G 3C,8G 9C 10C 6C,9G 9C 3C,7G 5C,9G 5C,9H 9CBARLEY 7G 4C,9G 3C,9G 10C 10C 9C 9H 5C,9G 6C,9G 10C PREEMERGENCECOTTON 0 2G 0 9G 4G 9G 2G 7G 0 1HMORNING GLORY 0 2C,3G 0 7H 8G 9G 2H 8H 2G 4GCOCKLEBUR 0 3C,4H 2C 8H 3C,3H 9H 0 3C,4HNUTSEDGE 0 3G 0 10E 3C,8G 9G 0 9G 4C,6GCRABGRASS 0 2G 2G 4G 4C,9G 4C,9G 0 5G 0 9GBARNYARD GRASS 0 2C,7H 0 3C,6H 2C,2H 9H 0 3C,8H 1H 3C,5HWILD OATS 0 3G 2G 3C,8H 2C,5G 3C,8G 0 3C,6G 2C 3C,7GWHEAT 0 8G 4G 3C,9H 8G 3C,9H 3G 9H 0 3C,7GCORN 0 3C,7H 2G 3C,7H 3C,9G 3C,9G 2G 3C,8H 2G 3C,9HSOYBEAN 2G 4C,6G 2C,2H 3C,6H 7H 9H 2C,2H 7H 3C,3G 3C,8GRICE 1C 3C,8H 5G 9H 9H 10E 2C,5G 9H 8G 5C,9GSORGHUM 2C,2G 9H 3C,7G 10H 9H 10E 9H 5C,9H 3C,7G 9HCHEATGRASS 0 8G 0 3G 8G 3C,9G 5G 9G 8G 9GSUGAR BEETS 5H 3G 2G 9G 3G 9G 0 6G 0 8GVELVETLEAF 0 1H 0 8H 1H 9G 0 6H 2G 3HGIANT FOXTAIL 0 4G 0 5G 5G 3C,9G 0 3C,8H 0BARLEY 3G 9G 7G 8G 9G 9G 3C,8G 9G 1C 7G__________________________________________________________________________ CMPD 14 CMPD 15 CMPD 16 CMPD 17 CMPD 18RATE RATE = KG/HA 0.05 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 4C,9G 5G 2C,9H 2G 9G 3C,9G 2C,9G 2C,9G 10CMORNING GLORY 4C,9G 0 0 0 1C 4C,9G 10C 3C,8G 3C,8GCOCKLEBUR 10C 4G 2C,5G 3G 3C,8H 9C 10C 10C 9CNUTSEDGE 2C,8G 0 0 2G 2C,7G 8G 3C,8G 7G 9GCRABGRASS 3G 2G 2C,5G 2G 3C,5G 3G 6G 7G 6GBARNYARD GRASS 3C,8H 3C,8H 9C 3C,8H 9C 3C,8H 5C,9G 4C,8H 4C,9HWILD OATS 3C,8G 2C,2G 5C,9G 4G 3C,8G 4C,9G 9G 5C,9G 6C,9GWHEAT 9G 9C 9C 8G 6C,9G 9G 3C,9G 8G 9CCORN 9G 9G 4U,9G 9G 5U,9C 10C 10C 2C,9G 9CSOYBEAN 4C,9G 3C,6H 3C,9H 2C,8H 4C,9G 4C,8G 4C,9G 4C,9G 9CRICE 9C 3C,9G 9C 5C,9G 9C 9C 10C 9C 9CSORGHUM 3C,4G 3C,6G 3C,8H 3C,8H 3C,8G 9C 9C 5C,9G 10CCHEATGRASS 3C,9G 4C,9G 9C 5C,9G 9C 9C 9C 5C,9G 9CSUGAR BEETS 10C 3C,4H 3C,7H 3C,5H 9C 5C,9G 10C 4C,8G 9CVELVETLEAF 4C,9H 0 2G 3G 3C,7G 4C,8H 9C 3C,8H 9CGIANT FOXTAIL 4C,9G 3C,8G 9C 4C,9G 9C 3C,9G 4C,9G 4C,8H 4C,9GBARLEY 3C,4G 3C,8G 2C,9G 2C,8G 4C,9G 4C,9G 3C,9G 9G 9C PREEMERGENCECOTTON 0 0 7G 0 4G 0 2G 0 3C,7HMORNING GLORY 2C 0 2C 0 3G 0 0 0 3GCOCKLEBUR 1C 5G 7G 0 1CNUTSEDGE 0 0 4G 0 0 0 0 0 4GCRABGRASS 0 2G 3G 0 0 0 0 0 8GBARNYARD GRASS 0 2G 4G 0 5G 0 0 0 1HWILD OATS 4G 0 4G 0 2G 0 0 0 4GWHEAT 0 0 7G 0 7G 0 0 0 0CORN 0 3C,6G 2C,8G 0 2C,8G 0 0 2C 4C,9HSOYBEAN 2G 0 0 0 2G 0 2G 0 3C,3HRICE 2G 3G 8G 5G 9H 0 2G 2G 4C,8HSORGHUM 2C 1C 1C,7G 0 1C,7G 0 1C 2C,5G 3C,9HCHEATGRASS 5G 2G 7G 0 2G 0 0 0 0SUGAR BEETS 2H 0 6G 1H 8G 0 0 1H 7HVELVETLEAF 0 0 0 0 0 0 0 3GGIANT FOXTAIL 0 0 7G 3G 8G 0 0 0 2GBARLEY 3G 0 3C,7G 0 1C 0 2C 0 3C,6G__________________________________________________________________________ CMPD 19 CMPD 20 CMPD 21 CMPD 22 CMPD 23RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 2C,9H 10C 0 5H 0 1C 4G 2C,9G 3C,8H 2C,9HMORNING GLORY 4C,8H 5C,9G 0 1C 0 0 2C,7G 3C,7H 3C,7G 3C,6HCOCKLEBUR 10C 9C 1H 3C,7H 0 1H 3C,8H 9C 3C,8H 3C,8HNUTSEDGE 7G 3C,6G 0 0 0 5G 6G 7G 7G 5GCRABGRASS 5G 7G 0 3C,7G 0 0 5G 2C,7G 3G 5GBARNYARD GRASS 3C,8H 5C,7H 3C,6G 5C,9H 3C,5G 3C,8H 6C,9G 9C 5C,9H 4C,8GWILD OATS 4C,9G 5C,9G 3C,8G 6C,9G 2C,8G 2C,8G 5C,9G 6C,9G 4C,8G 3C,8GWHEAT 7G 6G 3C,8G 5C,9G 5C,9G 6C,9G 4C,9G 6C,9G 4C,9G 9GCORN 2C,9G 5U,9G 3C,7G 4C,9H 3C,7H 3C,9G 3C,9G 3U,9C 3C,9G 3C,9GSOYBEAN 9C 5C,9G 2H 3C,8H 0 0 5C,9G 5C,9G 3C,8G 3C,9GRICE 9C 9C 2C,8G 5C,9H 3C,7G 2C,8G 9C 9C 9C 6C,9GSORGHUM 5C,9G 4C,9G 3C,6G 3C,9H 3C,6G 3C,8H 6C,9G 6C,9G 5C,9G 5C,9GCHEATGRASS 9C 5C,9G 2C,8G 6C,9G 2C,7G 3C,8G 6C,9G 9C 4C,9G 3C,9GSUGAR BEETS 4C,8G 4C,9G 2H 3C,3H 1H 2C,2H 3C,7G 9C 4C,8G 3C,7HVELVETLEAF 2C,8H 9C 0 2C,4H 0 2C,5G 6H 3C,8H 7H 4C,8HGIANT FOXTAIL 4C,9G 5C,9H 3C,7G 4C,9G 3C,8G 3C,7G 3C,9G 9C 4C,9G 4C,9HBARLEY 2C,9G 3C,9G 3C,8G 4C,9H 2C,9G 3C,9G 5C,9G 4C,9G 2C,8G 3C,9G PREEMERGENCECOTTON 1C 2C,3G 0 0 0 0 0 0 0 0MORNING GLORY 0 1C 0 0 0 0 0 0 0 0COCKLEBUR 3C,3H 0 0 0 2H 0 0 0NUTSEDGE 0 0 0 0 0 0 0 0 0 0CRABGRASS 0 0 0 0 0 0 0 0 0 0BARNYARD GRASS 0 0 0 0 0 0 0 0 0 0WILD OATS 0 7G 0 0 0 0 0 0 0 0WHEAT 0 0 0 0 0 0 0 0 0 0CORN 2C,4G 3C,9H 0 0 0 0 0 0 0 0SOYBEAN 0 3C,3H 0 0 0 0 0 0 0 0RICE 2G 9H 0 0 0 0 0 0 0 0SORGHUM 3C,7H 3C,9H 0 0 0 0 0 0 0 0CHEATGRASS 0 5G 0 0 0 0 0 0 0 0SUGAR BEETS 2G 3G 0 0 0 2H 0 0 0 0VELVETLEAF 0 2C,2G 0 0 0 0 0 0 0 0GIANT FOXTAIL 0 4G 0 0 0 0 0 0 0 0BARLEY 0 3C,6G 0 0 0 0 0 0 0 0__________________________________________________________________________ CMPD 24 CMPD 25 CMPD 26 CMPD 27 CMPD 28RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 9C 10C 0 1C 0 0 0 3G 0 4HMORNING GLORY 3C,8G 5C,9G 0 1H 0 0 0 0 0 0COCKLEBUR 10C 10C 0 2H 0 0 0 1H 0 3GNUTSEDGE 10C 9C 0 2C,3G 0 0 0 0 0 0CRABGRASS 5G 8G 0 0 0 0 0 4G 0 0BARNYARD GRASS 9C 9C 0 0 0 3H 1H 4C,9G 0 4GWILD OATS 2C,8G 9G 0 0 0 0 0 3G 0 0WHEAT 9G 9G 0 0 0 4G 0 2G 0 0CORN 5U,9G 4U,9G 0 0 0 2C,8H 0 2C,9G 0 3C,7GSOYBEAN 9C 9C 0 2H 0 4H 0 2C,7H 0 3HRICE 9C 9C 0 2G 0 3C,9G 0 4C,9G 0 3GSORGHUM 9G 5C,9G 0 1C 0 2C 0 4C,8H 0 2C,5GCHEATGRASS 8G 9C 0 0 0 3C,8G 2G 2C,9G 0 5GSUGAR BEETS 9C 10C 0 3C,8G 0 3H 2H 4G 0 1HVELVETLEAF 10C 10C 0 2H 0 3G 0 0 0 0GIANT FOXTAIL 3C,8G 4C,9G 0 0 0 3C,7G 2G 5C,9G 0 1C,8GBARLEY 2C,8G 3C,9G 0 0 0 2G 0 3C,8G 0 0 PREEMERGENCECOTTON 9G 0 0 0 0 0 2G 0 2GMORNING GLORY 2G 9G 0 0 0 0 0 3G 0 0COCKLEBUR 6H 9H 0 0 0 0 2G 0 1GNUTSEDGE 4C,9G 10E 0 0 0 0 0 0 0 0CRABGRASS 4G 8G 0 0 0 0 0 0 0 0BARNYARD GRASS 3G 9H 0 0 0 0 0 0 0 0WILD OATS 6G 4C,8G 0 0 0 0 0 0 0 0WHEAT 6G 9H 0 0 0 0 0 0 0 0CORN 2C,9G 5C,9G 0 0 0 0 0 2G 0 0SOYBEAN 6G 9H 0 0 0 0 0 2G 0 0RICE 10H 10E 0 0 0 0 0 0 0 0SORGHUM 9H 10E 0 0 0 0 0 0 0 0CHEATGRASS 8G 9H 0 0 0 0 0 2G 0 0SUGAR BEETS 9G 9G 0 0 0 0 0 3G 0 3GVELVETLEAF 2G 4C,8G 0 0 0 0 0 2G 0 0GIANT FOXTAIL 5G 9H 0 0 0 0 0 2G 0 0BARLEY 2C,7G 9G 0 0 0 0 0 0 0 0__________________________________________________________________________ CMPD 29 CMPD 30 CMPD 31 CMPD 32 CMPD 33RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 0 1H 0 0 0 2G 0 0 0 0MORNING GLORY 0 0 0 0 0 0 0 0 0 0COCKLEBUR 0 2H 2G 3G 0 0 0 0 0 0NUTSEDGE 0 0 0 0 0 0 0 0 0 0CRABGRASS 0 0 0 3G 0 3G 0 0 0 0BARNYARD GRASS 0 2G 0 2C,5G 0 7H 0 0 0 0WILD OATS 0 0 0 0 0 3C,5G 0 0 0 0WHEAT 0 0 0 8G 0 3C,8G 0 0 0 0CORN 0 0 0 3C,7G 0 2C,1G 0 0 0 0SOYBEAN 0 1H 0 2C,8H 0 0 0 0 0 0RICE 0 0 0 3C,7G 0 8G 0 0 0 0SORGHUM 0 0 0 2C 0 2C,2G 0 0 0 0CHEATGRASS 0 0 0 7G 0 3G 0 0 0 0SUGAR BEETS 0 0 0 2C,5H 0 3C,6G 0 0 0 0VELVETLEAF 0 0 0 0 0 2G 0 0 0 0GIANT FOXTAIL 0 3H 0 3C,7H 0 3C,8G 0 0 0 0BARLEY 0 0 0 2G 0 4G 0 0 0 0 PREEMERGENCECOTTON 0 5G 2G 6G 0 2G 0 0 0 0MORNING GLORY 0 0 0 2G 0 0 0 0 0 0COCKLEBUR 0 0 0 2G 0 2H 0 0 0 0NUTSEDGE 0 0 0 0 0 0 0 0 0 0CRABGRASS 0 0 0 3G 0 0 0 0 0 0BARNYARD GRASS 0 0 0 0 0 2G 0 0 0 0WILD OATS 0 0 0 0 0 0 0 0 0 0WHEAT 0 0 0 0 0 0 0 0 0 0CORN 0 0 0 0 0 0 0 0 0 0SOYBEAN 0 3H 0 2C,6G 0 2G 0 0 0 0RICE 0 0 0 6G 0 3G 0 0 0 0SORGHUM 0 0 0 4G 0 2G 0 0 0 0CHEATGRASS 0 0 0 0 0 0 0 0 0 0SUGAR BEETS 0 3G 3G 5G 0 2G 0 0 0 0VELVETLEAF 0 0 0 2G 0 0 0 0 0 0GIANT FOXTAIL 0 0 0 0 0 2G 0 0 0 0BARLEY 0 0 0 0 0 0 0 0 0 0__________________________________________________________________________
__________________________________________________________________________ CMPD 34 CMPD 35 CMPD 36 CMPD 37 CMPD 38RATE RATE=KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 0 3C,8H 8G 10C 6G 2C,9G 7G 8G 7G 9HMORNING GLORY 0 0 4C,8G 10C 3C,3H 3C,8G 1H 3C,8G 2C,6G 3C,7HCOCKLEBUR 0 1C 10C 10C 4C,9H 5C,9H 3H 7H 2C,6G 2C,7GNUTSEDGE 0 0 5C,9G 4C,9G 3C,8G 2C,8G 0 7G 0 2C,4GCRABGRASS 2G 6G 7G 3C,8G 2G 5G 0 3G 0 0BARNYARD GRASS 3C,8H 3C,6G 4C,9H 9C 3C,7H 3C,7H 0 2G 0 0WILD OATS 2C,7G 5G 4C,9G 9C 3G 4G 0 3G 0 0WHEAT 3C,9G 8G 9G 9C 7G 5G 0 3G 0 0CORN 3C,9G 2C,7H 5U,9C 10C 3C,9H 4C,9G 0 2G 0 0SOYBEAN 2C,7H 4H 9C 10C 5C,9G 4C,9G 3C,6G 3C,8G 2C,5G 2C,8GRICE 9C 9C 9C 9C 3G 2C,3G 2C,4G 6G 5G 3C,7GSORGHUM 3C,7G 2C,3G 5C,9G 9C 3C,8H 3C,7G 2G 2C,8G 2G 2C,2GCHEATGRASS 3C,8G 3C,7G 9C 9C 9G 3C,8G 2G 5G 0 2GSUGAR BEETS 5G 3C,6H 9C 10C 3C,6H 4C,8H 0 3G 0 0VELVETLEAF 0 1H 6C,9G 10C 8G 6C,9G 1H 3C,8G 3G 6GGIANT FOXTAIL 3C,8G 3C,8G 4C,8G 4C,9G 3C,7G 4C,8G 0 3G 0 0BARLEY 2C,8G 3C,7G 3C,9G 5C,9G 5G 2C,5G 0 6G 0 6G PREEMERGENCECOTTON 0 0 3G 7G 0 0 0 0 0 0MORNING GLORY 0 0 0 5G 0 0 0 0 0 0COCKLEBUR 0 0 0 2H 3C,3H 0 2G 0 2GNUTSEDGE 0 0 0 9G 0 0 0 0 0 0CRABGRASS 0 0 0 3C,6G 0 0 0 0 0 0BARNYARD GRASS 0 0 0 7H 0 2C,7G 0 5G 0 7GWILD OATS 0 0 0 4G 0 0 0 2G 0 3GWHEAT 0 0 0 7G 0 0 0 2G 0 0CORN 0 0 0 9H 0 3C,7G 0 3C,7G 0 2C,5GSOYBEAN 0 0 0 9H 0 2C,2H 0 2C,2H 0 1CRICE 0 0 8G 4C,9H 0 2G 0 2C,7G 0 3GSORGHUM 0 0 9G 3C,9H 0 3C,7G 0 2C,7G 0 2GCHEATGRASS 0 0 9G 9G 0 8G 0 8G 0 7GSUGAR BEETS 0 0 3H 9C 0 0 0 6H 0 8GVELVETLEAF 0 0 0 6H 1H 0 0 0 0 1HGIANT FOXTAIL 0 0 0 3G 0 2G 0 0 0 0BARLEY 0 0 0 7G 0 0 0 2C,3G 0 0__________________________________________________________________________ CMPD 39 CMPD 40 CMPD 41 CMPD 42 CMPD 43RATE RATE=KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 10C 9C 4C,8H 9H 9H 9H 10C 9C 10C 9CMORNING GLORY 9C 10C 3C,7H 5C,9G 4C,8H 4C,9H 3H,6G 5C,9G 3C,7G 4C,8GCOCKLEBUR 9C 10C 3C,7H 9C 4C,8H 5C,9H 4C,9H 10C 5C,9G 10CNUTSEDGE 9G 2C,9G 3G 9G 2G 9G 3C,9G 4C,9G 4C,9G 9GCRABGRASS 6G 3C,9G 0 8G 0 2G 4G 5G 3C,5G 4C,8GBARNYARD GRASS 4C,8H 10C 3C,5H 9H 4C,7H 3C,7H 2C,9H 4C,9H 3C,9H 3C,9HWILD OATS 4C,9G 4C,9G 9G 2C,9G 7G 9G 2C,3G 2C,8G 3C,5G 4C,8GWHEAT 9G 5C,9G 7G 9G 7G 9 4G 5G 4G 8GCORN 6G 2C,7G 0 2G 0 0 3C,9H 2C,9G 3C,9H 2C,7GSOYBEAN 4C,9G 9C 3C,7H 5C,9G 4C,8G 4C,9G 5C,9G 6C,9G 4C,9G 4C,9HRICE 5C,9G 9C 4C,9G 5C,9G 5C,9G 5C,9G 5C,9G 9G 6C,9G 5C,9GSORGHUM 4C,9G 9C 4C,9G 3C,9G 5C,9G 4C,9G 4C,9G 3C,9H 4C,8G 4C,9GCHEATGRASS 5G 3C,8G 3C,9G 2C,9G 4C,8G 3C,9G 3C,8G 3C,9G 2C,8G 3C,9GSUGAR BEETS 6G 9C 5C,8H 9C 9C 9C 9C 9C 9C 9CVELVETLEAF 4C,9H 10C 3C,7H 4C,8H 3C,6G 5C,9H 4C,8H 9C 3C,8H 9CGIANT FOXTAIL 5C,9G 9C 3C,8G 5C,9G 4C,9G 4C,9G 3C,9G 4C,9H 4C,8G 3C,9HBARLEY 8G 9C 0 5G 0 2G 3G 6G 2G 8G PREEMERGENCECOTTON 7G 9G 2G 5G 3G 7G 3G 7G 4G 7GMORNING GLORY 3C,7H 8G 0 3C,7H 0 2C,5H 2G 6G 3G 4GCOCKLEBUR 8H 4G 3C,5G 2C,2H 0 2H 3HNUTSEDGE 9G 10E 0 0 0 0 0 9G 0 10ECRABGRASS 3C,3G 9H 0 2C,2G 0 6G 2G 8G 5G 9HBARNYARD GRASS 0 3C,7H 0 0 0 2G 2G 9H 2G 9HWILD OATS 2C,6G 3C,8G 2G 6G 0 3C,7G 2G 7G 2G 5GWHEAT 2C,8G 2C,8H 0 6G 0 2C,8H 0 8G 2G 5GCORN 3C,5G 8G 0 3C,5G 0 3C,5G 4G 9G 2G 3C,9GSOYBEAN 2C,5H 9H 2H 3C,7H 3C,4G 3C,5H 5G 3C,6H 3G 8HRICE 9H 10H 2C,2G 3C,8G 2G 9H 9H 3C,9H 7H 9HSORGHUM 3C,7G 9H 3C,3G 3C,8H 2C,2G 4C,9H 0 3C,6H 0 3C,7GCHEATGRASS 0 7G 7G 8G 7G 3C,8G 6G 8G 5G 9HSUGAR BEETS 6G 7G 7G 9G 5G 4C,9G 3H 9G 8G 5GVELVETLEAF 3C,6H 5C,9G 0 2C,5G 0 3C,3H 0 6H 0 2HGIANT FOXTAIL 3C,7G 9H 0 3C,6G 0 3C,8H 6G 9H 4G 9HBARLEY 5G 8G 0 3G 0 2G 0 7G 0 7G__________________________________________________________________________ CMPD 44 CMPD 45 CMPD 46 CMPD 47 CMPD 48RATE RATE=KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 9C 10C 9H 10C 0 0 0 0 0 0MORNING GLORY 5C,9G 10C 4C,9G 10C 0 1H 0 1C,1H 0 0COCKLEBUR 10C 10C 10C 10C 0 1H 0 0 0 0NUTSEDGE 9G 9G 9G 4C,9G 0 0 0 0 0 0CRABGRASS 2C,8G 4C,9G 6G 6C,9G 0 0 0 0 0 0BARNYARD GRASS 4C,8H 5C,9H 4C,8H 9C 0 0 0 0 0 0WILD OATS 8G 3C,9G 2C,9G 6C,9G 0 0 0 0 0 0WHEAT 5G 8G 9G 2C,9G 0 0 0 0 0 0CORN 3C,8H 9G 3G 3C,8G 0 0 0 0 0 0SOYBEAN 5C,9G 9C 5C,9G 9C 0 1H 0 0 0 0RICE 5C,9G 6C,9G 9C 9C 0 0 0 0 0 0SORGHUM 3C,9G 5C,9G 3C,9G 6C,9G 0 0 0 0 0 0CHEATGRASS 4C,9G 6C,9G 1C 2C,7G 0 0 0 0 0 0SUGAR BEETS 3C,5G 9C 3C,8G 10C 0 2G 0 1H 0 2HVELVETLEAF 9G 10C 3C,8H 10C 0 0 0 0 0 3GGIANT FOXTAIL 3C,8G 5C,9H 4C,9H 10C 0 0 0 0 0 0BARLEY 8G 2C,9G 9G 6C,9G 0 0 0 0 0 0 PREEMERGENCECOTTON 8G 9G 5G 9G 0 0 0 0 0 0MORNING GLORY 2G 6H 2C,3H 9H 0 2G 0 0 0 2GCOCKLEBUR 3C,3H 9H 2H 9H 0 0 0 0 0NUTSEDGE 8G 10E 7G 10E 0 0 0 0 0 0CRABGRASS 5G 10E 3C,9G 0 0 0 0 0BARNYARD GRASS 5G 4C,9H 2G 3C,7H 0 0 0 0 0 0WILD OATS 2C,5G 2C,8G 2C,5G 5C,9H 0 0 0 0 0 0WHEAT 0 5G 5G 4C,9H 0 0 0 0 0 0CORN 3C,6G 3C,9G 1C 4C,9G 0 0 0 0 0 0SOYBEAN 3G 3C,8H 2C,4G 9H 0 0 0 0 0 0RICE 8H 10H 3C,9H 10H 0 0 0 0 0 0SORGHUM 3C,7G 9H 3C,7H 10H 0 0 0 0 0 0CHEATGRASS 7G 3C,8G 2G 6G 0 0 0 0 0 0SUGAR BEETS 7G 8G 4H 9G 0 0 0 0 0 2GVELVETLEAF 0 4C,8G 2C,3G 4C,7H 0 0 0 0 0 0GIANT FOXTAIL 2G 4C,9H 5G 4C,8H 0 0 0 0 0 0BARLEY 4G 8G 8G 4C,9G 0 0 0 0 0 0__________________________________________________________________________
__________________________________________________________________________ CMPD 49 CMPD 50 CMPD 51 CMPD 52 CMPD 53RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 2C,9G 9C 5C,9G 5C,9G 0 0 0 0 0 2C,2GMORNING GLORY 4G 7G 2H,5G 9C 0 1C 2C,4G 2C,3G 3C,8GCOCKLEBUR 10C 10C 10C 10C 0 0 0 0 1H 2C,5GNUTSEDGE 3C,9G 9G 9G 9G 0 0 0 0 0 0CRABGRASS 0 3C,7G 2G 2C,5G 0 0 0 0 0 3GBARNYARD GRASS 3C,9G 4C,9H 3C,9H 5C,9H 1H 2C,5G 0 1H 1H 2C,4HWILD OATS 2C,9G 5C,9G 4C,9G 5C,9G 2C,2G 7G 0 0 0 1CWHEAT 9G 9G 5C,9G 9G 8G 7G 7G 0 3G 8GCORN 10C 9C 9C 3U,9G 0 2G 0 0 0 2C,2HSOYBEAN 9C 9C 9C 6C,9G 1H 2C,2H 1H 3C,4H 2C,2G 3C,3GRICE 9C 9C 9C 9C 4G 8G 4G 5G 2G 3C,4GSORGHUM 9C 9C 9C 5C,9G 0 2G 0 0 0 3C,6GCHEATGRASS 9C 9C 9C 9C 2G 5G 0 0 0 2C,6GSUGAR BEETS 10C 9C 9C 9C 0 3C,4G 2G 2C,2H 3C,7G 3C,8HVELVETLEAF 9C 10C 9C 9C 0 0 0 0 2G 2C,6GGIANT FOXTAIL 3C,5G 4C,9G 2C,7G 5C,9G 0 2G 0 2G 0 3C,5GBARLEY 5C,9G 6C,9G 9C 5C,9G 0 2G 0 0 0 0 PREEMERGENCECOTTON 0 5G 0 2C,8G 0 0 0 0 0 1CMORNING GLORY 0 0 0 0 0 2G 0 0 0 2CCOCKLEBUR 0 2C,2H 0 3C,6H 0 0 0 0NUTSEDGE 0 0 0 2G 0 2G 0 0 0 0CRABGRASS 0 0 0 2G 0 2G 0 0 0 0BARNYARD GRASS 0 2G 0 0 0 0 0 0 0 2GWILD OATS 0 15 0 0 0 0 0 0 0 0WHEAT 0 0 0 0 0 0 0 0 0 0CORN 0 2C,2G 0 2C,2G 0 0 0 0 0 3C,3GSOYBEAN 2G 2C,5G 0 3C,7G 0 2G 0 2G 0 0RICE 0 3C,8G 0 2C,8H 0 0 0 0 0 0SORGHUM 2C 3C,8H 0 3C,7G 0 0 0 0 0 3C,7GCHEATGRASS 0 7G 0 7G 0 2G 0 0 0 0SUGAR BEETS 3H 0 4H 0 2G 0 3G 0 1HVELVET 0 3G 0 2C,5G 0 0 0 0 0 0GIANT FOXTAIL 0 0 0 2G 0 2G 0 0 0 0BARLEY 0 0 0 0 0 0 0 0 0 0__________________________________________________________________________ CMPD 54 CMPD 55 CMPD 56 CMPD 57 CMPD 58RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 2G 1C 5C,9G 9C 9C 9C 4C,9H 9C 9H 7GMORNING GLORY 3C,6G 3C,7H 3C,6G 4C,9G 9C 10C 9C 10C 2C,5G 2C,4GCOCKLEBUR 1H 2C,5G 10C 10C 10C 10C 10C 10C 5G 3C,8HNUTSEDGE 0 0 9G 8G 9GCRABGRASS 0 2C,2G 2C,7G 4C,9G 5G 4C,9G 6G 4C,9G 2G 4C,9GBARNYARD GRASS 1H 3C,3H 5C,9G 5C,9G 4C,9G 5C,9G 4C,9G 5C,9G 2C,6H 3C,8GWILD OATS 0 2C 3C,9G 3C,9G 9G 9G 2C,9G 4C,9G 3G 3C,9GWHEAT 0 4G 9G 9G 9G 4C,9G 9G 9G 3G 2C,9GCORN 0 0 3C,9G 5C,9G 4C,9G 3C,9G 4C,9G 4C,9G 2G 3C,9HSOYBEAN 2G 3C,4G 9C 9C 9C 9C 9C 9C 3C,5G 3C,8GRICE 0 2C,2G 5C,9G 9C 5C,9G 9C 9G 4C,9G 3C,4G 4C,9GSORGHUM 0 3C,7G 4C,9G 4C,9G 3C,9G 4C,9G 5C,9G 4C,9G 4C,9G 5C,9GCHEATGRASS 0 1C 9C 5C,9G 5C,9G 5C,9G 4C,9G 5C,9G 2G 2C,8GSUGAR BEETS 3C,7G 3C,7H 9C 9C 9C 9C 9C 9C 4C,8H 5C,9GVELVETLEAF 4G 3C,7G 9C 10C 9C 9C 3H,7G 4C,8H 2C,7G 3C,8GGIANT FOXTAIL 0 2C,2G 5C,9G 9C 3C,6G 9C 3C,7G 9C 7G 3C,7GBARLEY 0 0 5C,9G 9C 3C,9G 8C,9G 2C,7G 8G 0 3G PREEMERGENCECOTTON 0 0 8G 8G 7G 8G 4G 9G 3G 3C,7GMORNING GLORY 0 3C,3H 4G 3G 1C 6H K0 2G 0 0COCKLEBUR 0 2C,2H 8H 3C,4G 8H 0 3C,5H 0 2C,2HNUTSEDGE 0 0 10E 10E 10E 10E 3G 10E 0 0CRABGRASS 0 0 3C,8G 9H 2G 3C,8H 9H 10E 6G 3C,8GBARNYARD GRASS 0 1C 3C,6G 9H 3G 4C,9H 2G 3C,8H 0 3C,7GWILD OATS 0 0 3G 3C,6H 3G 3C,7G 0 3C,6G 0 2GWHEAT 0 0 3G 9H 0 3G 0 7G 0 7GCORN 0 2C 1C 9G 4C,9G 4C,6G 2G 2C,3G 0 2C,3GSOYBEAN 0 0 1C,2H 4C,6H 3C,6H 3C,6H 2G 3C,3G 0 2C,3GRICE 0 2G 7G 10E 3C,6G 9H 0 9H 0 8HSORGHUM 0 3C,4G 3C,4G 3C,9H 4C,9H 9G 4C,9H 2C,2G 3C,8HCHEATGRASS 0 0 9G 9H 4G 3C,9H 2G 4C,8G 3G 8GSILVER BEETS 0 3H 3G 6G 7G 3C,7G 0 4C,8G 7G 4C,8GVELVETLEAF 0 1C 3G 2C,7G 6G 9G 0 2G 0 3C,7HGIANT FOXTAIL 0 0 1C 9H 3G 3C,9H 0 6H 3G 3C,8GBARLEY 0 0 0 2C,7G 2C,5G 3C,8G 0 2C,4G 0 3G__________________________________________________________________________ CMPD 59 CMPD 60 CMPD 61 CMPD 62 CMPD 63RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 0 3G 0 0 0 2C,5G 2G 2C,3G 2G 3C,5GMORNING GLORY 0 0 0 3G 2H 0 1C 2G 1C,1H 2C,4GCOCKLEBUR 0 1H 0 0 5G 2G 3G 2H 2G 2C,3GNUTSEDGE 0 0 5G 9G 3G 8G 0CRABGRASS 0 3G 0 5G 0 8G 4G 3C,7G 0 2C,5GBARNYARD GRASS 0 3C,5G 0 2C,4G 2H 2C,8H 0 3C,5G 2G 3C,7GWILD OATS 0 0 0 3G 0 4G 0 4G 0 0WHEAT 0 0 0 5G 0 5G 0 3G 0 0CORN 0 3C,4G 2G 3C,8G 3C,4G 3C,8G 2C 2C,8G 2G 2CSOYBEAN 0 1C 0 1C,1H 2H 2C,2G 0 2C,3H 2C,2G 3C,5HRICE 2G 3C,5G 0 3C,4G 0 5C,8G 0 5C,9G 1C 0SORGHUM 0 2G 0 2G 0 0 0 2G 0 3C,5GCHEATGRASS 0 0 0 3G 2C,4G 5G 0 6G 0 2C,5GSUGAR BEETS 3C,7G 3C,7H 3C,7H 4C,8H 5C,9H 5C,9G 9C 9C 3C,6G 3C,8GVELVETLEAF 0 0 0 0 3C,7G 3C,7G 3C,8G 3C,7G 0 2C,5GGIANT FOXTAIL 0 3G 0 4G 2G 3C,8G 3G 2C,9G 0 3C,7GBARLEY 0 0 0 2G 0 0 0 4G 0 0 PREEMERGENCECOTTON 0 0 0 0 0 0 0 3C,3G 0 0MORNING GLORY 0 2G 0 0 9H 1H 0 2C,2G 0 2HCOCKLEBUR 0 1C 0 4G 0 1C 0 2C,3H 0 2GNUTSEDGE 0 0 0 0 0 5G 0 5G 0 0CRABGRASS 0 3G 0 5G 2H 3C,7G 0 4C,8G 1C 3C,5GBARNYARD GRASS 0 4G 0 3C,7G 3H 5G 0 7G 0 3C,5GWILD OATS 0 0 0 2C,3G 0 2G 0 2C,2G 0 0WHEAT 0 0 0 5G 0 0 0 5G 0 0CORN 0 2G 0 4C,7G 3C,5G 3C,7G 0 4C,8H 0 0SOYBEAN 0 0 0 0 0 0 0 0 0 0RICE 0 7G 0 2G 3G 3C,8H 0 4C,9H 0 0SORGHUM 0 2G 0 0 2C,3G 0 0 0 0 3C,4GCHEATGRASS 0 0 0 0 2G 7G 0 3C,8G 0 2GSUGAR BEETS 0 3C,7G 0 4C,9G 7G 3C,8G 5G 5C,9G 0 5GVELVETLEAF 0 2G 0 2C,3G 0 3C,7G 0 3C,7G 0 2CGIANT FOXTAIL 0 2G 0 3C,6G 6G 4C,8H 0 4C,8G 2G 3C,4GBARLEY 0 0 0 0 0 0 0 2G 0 0__________________________________________________________________________
__________________________________________________________________________ CMPD 64 CMPD 65 CMPD 66 CMPD 67 CMPD 68RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 0 3C,5G 4C,9G 5C,9G 3C,8G 9G 3C,9H 5C,9G 2G 8GMORNING GLORY 2C,3G 3C,7G 10C 10C 4C,9H 4C,9G 3C,8H 4C,9H 3C,6G 3C,8GCOCKLEBUR 2G 2C,3G 5C,9G 9C 3C,8G 4C,9G 2C,6G 4C,9G 2H 3C,7GNUTSEDGE 0 2C,9G 9G 9G 7GCRABGRASS 0 2C,8G 6G 9G 0 0 2G 3G 0 0BARNYARD GRASS 0 3C,7G 9H 9G 3G 3C,6G 3C,8H 3C,7H 0 0WILD OATS 0 0 8G 9G 0 0 9G 3C,9G 0 0WHEAT 0 7G 9G 9G 0 0 3G 8G 0 0CORN 0 2C,2G 2C,5G 3C,7G 0 2C,4G 0 3G 0 0SOYBEAN 3C,5G 3C,6G 5C,9G 5C,9G 3C,7G 3C,8G 3C,7G 3C,7G 3C,5H 3C,6HRICE 1C 2G 2C,8G 3C,9G 3C,7G 9G 3C,7G 7G 0 2GSORGHUM 0 3C,6G 3C,7G 3C,7G 0 2G 7G 3C,6G 0 0CHEATGRASS 0 2C,5G 9G 9G 0 0 2C,8G 8G 0 0SUGAR BEETS 3C,3G 4C,8H 3C,8H 9C 5C,9G 9C 5C,9H 9C 3C,8G 3C,8HVELVETLEAF 3G 3C,8G 4C,9G 9C 3C,7H 4C,9G 3C,8H 4C,8H 4G 4C,7HGIANT FOXTAIL 5G 3C,8G 3C,8G 3C,9G 3C,6G 2C,6G 3C,3G 3C,8G 2G 2GBARLEY 0 0 3G 5G 0 0 0 2G 0 0 PREEMERGENCECOTTON 0 2G 6G 8G 0 4G 0 7G 0 0MORNING GLORY 2G 2C,2G 7G 9G 0 7G 2G 2C,8G 0 0COCKLEBUR 1C 0 8H 0 0 9G 0NUTSEDGE 0 0 5G 9G 0 7G 0 9G 0 0CRABGRASS 0 2C,5G 2C,5G 3C,8G 0 3G 0 6G 0 0BARNYARD GRASS 0 3G 8H 9H 0 7G 0 9H 0 2GWILD OATS 0 3G 2C,7G 3C,7G 0 3G 2G 5G 0 0WHEAT 0 0 7G 9H 0 3G 0 7G 0 0CORN 0 2C,2G 3C,5G 3C,9G 0 3C,5G 2G 2C,5G 0 2GSOYBEAN 0 5G 2G 3C,6G 0 2C,3G 0 2C,3G 0 2GRICE 0 3G 8G 9H 2G 9H 0 9H 0 2GSORGHUM 0 3C,3G 3G 3C,9H 0 0 2G 3C,7G 0 0CHEATGRASS 0 2G 5G 8G 0 2G 0 6G 0 0SUGAR BEETS 0 2H 8G 3C,8G 0 8G 7G 3C,8G 0 0VELVETLEAF 0 1C 4G 4C,9G 0 6G 0 2C,5H 0 3GGIANT FOXTAIL 0 2C,6G 7G 9H 0 8G 2G 9H 0 4GBARLEY 0 0 2G 7G 0 0 0 7G 0 0__________________________________________________________________________ CMPD 69 CMPD 70 CMPD 71 CMPD 72 CMPD 73RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 3C,8H 9C 5G 9G 10C 9C 9C 10C 9C 9CMORNING GLORY 3C,8G 5C,9G 2C,5G 3C,8G 9C 10C 3C,5G 9C 10C 10CCOCKLEBUR 3C,6G 5C,9G 4G 3C,7H 10C 10C 10C 10C 10C 10CNUTSEDGE 5G 0 9C 4C,9G 5C,9G 9C 2C,8G 2C,9GCRABGRASS 0 5G 0 0 9C 10C 9C 9C 9C 9CBARNYARD GRASS 2C,7G 3C,9H 0 1H 9C 9C 9C 9C 9C 9CWILD OATS 6G 2C,8G 0 0 5C,9G 5C,9G 9C 5C,9G 4C,9G 5C,9GWHEAT 0 3G 0 0 9C 9C 9C 9C 9G 5C,9GCORN 0 3G 0 1C 10C 10C 10C 10C 9C 9CSOYBEAN 3C,8G 4C,9G 2C,2H 3C,7G 9C 9C 9C 9C 4C,7H 9CRICE 3C,7G 9G 3G 7G 9C 9C 9C 9C 9C 9CSORGHUM 0 3C,4G 0 1C 9C 9C 9C 9C 9C 9CCHEATGRASS 5G 8G 0 0 9C 9C 10C 9C 9C 9CSUGAR BEETS 3C,8G 9C 2C,3G 2C,7G 10C 10C 9C 9C 9C 10CVELVETLEAF 3C,8G 9C 2C,3G 3C,7H 9C 10C 5C,9G 10C 2C,7G 5C,8GGIANT FOXTAIL 5G 2C,6G 0 0 9C 10C 10C 10C 9C 10CBARLEY 0 3G 0 0 5C,9G 6C,9G 9C 9C 5C,9G 5C,9G PREEMERGENCECOTTON 2G 7G 0 0 8G 9G 9G 9G 7G 2C,8GMORNING GLORY 1C,1H 3C,8H 0 3C,3H 7G 8G 5G 9G 3C,7G 9GCOCKLEBUR 0 0 2G 9H 9H 8HNUTSEDGE 0 10E 0 0 9G 10E 10E 10E 8G 10ECRABGRASS 0 0 0 5C,9G 5C,9G 5C,9G 6C,9G 4C,8G 5C,9GBARNYARD GRASS 0 3G 0 0 9H 9H 9H 9H 3C,7G 9HWILD OATS 0 3G 0 0 4C,9H 5C,9H 3C,8G 3C,9H 2C,7G 3C,9HWHEAT 0 0 0 0 9H 10H 9H 10E 2C,8H 10ECORN 0 1C 0 0 9H 9H 9G 10H 3C,9G 9HSOYBEAN 0 3C,3H 0 0 9H 9H 9H 9H 3C,8H 9HRICE 0 9H 0 2G 10E 10E 10E 10E 3C,9H 10ESORGHUM 0 0 0 0 4C,9H 5C,9H 5C,9H 10H 3C,8G 10ECHEATGRASS 0 5G 0 0 9H 10E 9H 9H 8G 9HSUGAR BEETS 0 8G 0 3G 3C,9G 9C 9C 9G 7G 9CVELVETLEAF 2C,2G 8G 0 2C,3H 3C,8H 5C,9G 8G 9G 5G 3C,6GGIANT FOXTAIL 0 0 0 0 9H 10E 9H 10E 9H 9HBARLEY 0 3G 0 0 4C,9G 5C,9H 4C,9G 5C,9H 3C,9G 5C,9H__________________________________________________________________________ CMPD 74 CMPD 75 CMPD 76 CMPD 77 CMPD 78RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 10C 10C 2C,7G 9C 9C 9C 5C,9G 5C,9G 9C 10CMORNING GLORY 10C 10C 5C,9G 10C 4C,9G 10C 3C,8G 5C,9G 10C 10CCOCKLEBUR 10C 10C 4C,9H 9C 4C,9G 10C 5C,9G 10C 10C 10CNUTSEDGE 3C,9G 4C,9G 3C,6G 8G 0 3G 4C,9G 9G 2C,9G 9GCRABGRASS 10C 10C 4C,9H 9C 5C,9G 10C 5C,9G 9C 3C,9H 5C,9GBARNYARD GRASS 9C 10C 9C 9C 9C 9C 5C,9G 9C 3C,9H 9CWILD OATS 5C,9G 9C 4C,9G 5C,9G 4C,9G 9C 4C,9G 4C,9G 3C,8G 4C,9GWHEAT 9C 10C 4C,9G 9C 4C,9G 9C 9G 4C,9G 9G 2C,9GCORN 9C 10C 9C 9C 9C 10C 2C,9G 5C,9G 3C,9G 5C,9GSOYBEAN 9C 9C 9C 5C,9G 5C,9G 9C 9C 9C 9C 10CRICE 5C,9G 9C 9C 10C 9C 9C 9C 9C 9C 9CSORGHUM 9C 9C 9C 9C 5C,9G 9C 5C,9G 9C 3C,8H 4C,9GCHEATGRASS 9C 9C 5C,9G 10C 9C 10C 9C 10C 4C,9G 9CSUGAR BEETS 9C 9C 9C 9C 10C 9C 10C 10C 3C,5G 5C,9GVELVETLEAF 5C,9G 9C 3G 3C,7H 2C,4G 3C,8G 2C,6G 3C,9G 9C 10CGIANT FOXTAIL 10C 9C 9C 10C 10C 10C 5C,9G 9C 3C,8G 5C,9GBARLEY 9C 9C 9C 9C 9C 9C 4C,9G 5C,9G 4C,9G 5C,9G PREEMERGENCECOTTON 5G 9G 1H 8G 2G 9G 2C,5G 9G 4G 9HMORNING GLORY 9G 9G 0 9G 2C,2G 9G 8H 8H 6G 9GCOCKLEBUR 3C,7H 9H 5G 3C,8H 2C,5G 3C,7H 3C,5H 3C,8H 3C,5H 9HNUTSEDGE 10E 10E 2C,9G 10E 3G 4G 10E 10E 10E 10ECRABGRASS 5C,9G 5C,9H 5C,9G 5C,9G 3C,8G 5C,9H 4C,9G 5C,9G 4C,9G 4C,9GBARNYARD GRASS 4C,9H 9H 1H 9H 3C,6G 4C,9H 4C,8G 9H 9H 9HWILD OATS 4C,8G 5C,9H 3C,7G 4C,9H 3C,8G 3C,8H 2C,7G 3C,9H 2C,3G 4C,8HWHEAT 9H 9H 9H 5C,9H 9H 9H 2C,8G 2C,9H 7G 3C,9HCORN 4C,9G 10E 3C,9G 9H 4C,9G 10H 3C,9G 10H 9G 5C,9HSOYBEAN 9H 9H 3C,6G 9H 3C,7H 9H 3C,6G 9H 3C,9H 9HRICE 5C,9G 10E 5C,9H 10E 10E 10E 9H 10E 3C,8H 9HSORGHUM 5C,9G 10H 4C,5G 5C,9H 3C,9H 5C,9H 3C,8H 5C,9H 3C,8H 9HCHEATGRASS 9G 10E 9G 9H 9H 9H 2C,8G 9H 7G 9HSUGAR BEETS 9C 9C 8G 9G 7H 5C,9G 3C,7G 9C 4G 7GVELVETLEAF 7G 5C,9G 2G 3C,6G 2G 2C,4G 3C,3G 3C,7G 6G 5C,9GGIANT FOXTAIL 9H 9H 9H 9H 4C,9H 9H 4C,9H 9H 3C,7H 9HBARLEY 4C,9G 4C,9H 8G 5C,9H 3C,9G 3C,9H 2C,9G 9G 3C,8G 3C,9G__________________________________________________________________________ CMPD 79 CMPD 80 CMPD 81 CMPD 82 CMPD 83RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 10C 9C 2C 0 1H 3C,8G 9C 10C 9C 10CMORNING GLORY 5C,9G 10C 1C,1H 3C,7G 2C,5G 3C,8G 10C 10C 10C 10CCOCKLEBUR 10C 10C 4H 3C,8H 2C,3H 2C,3H 10C 10C 10C 10CNUTSEDGE 3C,8G 4C,9G 2G 0 3G 5G 2C,8G 9G 9G 5C,9GCRABGRASS 9C 9C 0 3C,6G 3C,6H 3C,7G 9C 9C 9C 9CBARNYARD GRASS 9C 10C 3C,3H 3C,7H 3C,8H 9C 5C,9G 9C 9C 10CWILD OATS 4C,9G 5C,9G 2C,4G 3C,6G 3C,9G 4C,9G 4C,9G 5C,9G 5C,9G 6C,9GWHEAT 3C,9G 4C,9G 9G 9G 9G 4C,9G 4C,9G 9G 5C,9G 6C,9GCORN 10C 10C 2C,8G 3C,9G 3C,9H 5C,9G 9C 10C 10C 10CSOYBEAN 5C,9G 9C 3C,3H 5C,9G 2H 2C,2H 4C,8H 9C 9C 9CRICE 9C 9C 8G 9C 4C,9G 5C,9G 9C 9C 9C 9CSORGHUM 9C 9C 0 3C,6G 3C,6H 4C,9G 9C 9C 9C 9CCHEATGRASS 10C 10C 8G 5C,9G 9G 9C 9C 9C 9C 9CSUGAR BEETS 10C 9C 3C,8H 5C,9G 3C,8H 9C 10C 9C 10C 10CVELVETLEAF 9C 10C 1C,1H 1H 2C,4G 3C,3G 2C,6G 5C,9G 5C,9G 9CGIANT FOXTAIL 10C 10C 3C,7G 3C,8G 3C,8G 5C,9G 9C 9C 10C 10CBARLEY 4C,9G 6C,9G 3C,7G 3C,9G 3C,8G 3C,9G 9C 9C 5C,9G 9C PREEMERGENCECOTTON 2G 2C,7G 0 2G 0 7G 8G 9G 6G 9GMORNING GLORY 6G 8G 2C,2H 0 0 7G 9G 9G 9G 9GCOCKLEBUR 2C,5G 2C,8H 2H 2H 0 7H 9H 3C,6HNUTSEDGE 9G 10E 0 0 0 0 9G 10E 10E 10ECRABGRASS 5C,9G 5C,9H 0 1C 0 3C,7G 4C,9G 5C,9H 5C,9G 5C,9GBARNYARD GRASS 4C,8H 9H 0 3C,6G 0 0 5G 9H 9H 9HWILD OATS 2G 3C,8H 0 0 0 3C,6G 3C,7G 4C,9H 4C,8H 5C,9HWHEAT 8G 9H 0 2C,3G 2G 7G 3C,9H 9H 3C,9H 9HCORN 3C,9G 3C,9H 3G 3C,8G 3C,6G 7H 3C,9H 10H 10H 9HSOYBEAN 3C,7H 3C,9G 0 2C,3G 0 1H 4C,8H 9H 9H 9HRICE 9H 10E 0 6G 0 8G 10E 9H 9H 10ESORGHUM 3C,9H 3C,9H 0 2G 0 0 4C,9H 5C,9H 10H 9CCHEATGRASS 3C,8G 10E 2G 2G 0 6G 9H 9H 5C,9G 10ESUGAR BEETS 6G 9C 0 5G 2G 9C 8G 9C 9C 9CVELVETLEAF 1H 2C,9G 0 0 0 2G 2G 4C,8H 2C,6G 5C,9GGIANT FOXTAIL 9H 9H 3G 2C,8G 0 6G 9H 9H 9H 9HBARLEY 2C,7G 3C,9G 0 2C,5G 2C,2G 2C,6G 4C,9G 3C,9H 4C,9H 9H__________________________________________________________________________ CMPD 84 CMPD 85 CMPD 86 CMPD 87 CMPD 88RATE RATE = KG/HA 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4 0.05 0.4__________________________________________________________________________ POSTEMERGENCECOTTON 9C 10C 2C,9H 9C 4C,9G 10C 9C 0 2GMORNING GLORY 5C,9G 10C 5C,8H 5C,9G 4C,8G 9C 10C 0 2C,4GCOCKLEBUR 5C,9G 10C 9C 9C 5C,9G 10C 10C 4H 3C,7GNUTSEDGE 3C,8G 9G 3G 9G 2C,9G 9G 9G 0 3C,5GCRABGRASS 5C,9G 9C 9C 4G,9C 6C,9G 6C,9G 5C,9G 1H 2GBARNYARD GRASS 9C 9C 9C 9C 9C 9C 9C 3C,5G 4C,9HWILD OATS 5C,9G 9C 5C,9G 9C 3C,9G 4C,9G 4C,8G 2C,5G 4C,8GWHEAT 4C,9G 10C 9C 9C 9G 9G 9G 8G 4C,9GCORN 10C 10C 9C 10C 3C,9G 9C 9C 3C,8G 2C,9HSOYBEAN 4C,9G 9C 4C,9G 9C 4C,8G 6C,9G 9C 1C,1H 3C,9GRICE 10C 9C 9C 9C 5C,9G 9C 9C 5C,9G 9GSORGHUM 9C 9C 9C 9C 5C,9G 9C 4C,9G 0 0CHEATGRASS 9C 10C 9C 9C 9C 9C 5C,9G 3C,9G 9CSUGAR BEETS 10C 10C 9C 10C 10C 10C 3C,7G 2G 4C,9GVELVETLEAF 2C,4H 9C 4C,6G 3C,7H 3C,7G 9C 10C 0 1CGIANT FOXTAIL 9C 10C 9C 10C 9C 9C 9C 3C,8G 5C,9HBARLEY 9C 9C 9C 9C 6C,9G 6C,9G 6C,9G 5G 3C,9H PREEMERGENCECOTTON 4G 7G 6G 7G 5G 2C,8G 8G 0 5GMORNING GLORY 2G 9G 3C,6H 9G 5G 9G 9G 2C,2H 0COCKLEBUR 1C,1H 8H 3C,3G 3C,7H 3C,3H 8H 9H 2HNUTSEDGE 10E 10E 2G 9G 5C,9G 10E 10E 0 0CRABGRASS 5C,9G 5C,9G 5C,9G 5C,9G 4C,8H 5C,9G 4C,9H 0 0BARNYARD GRASS 5G 9H 4C,8H 9H 4C,9H 9H 9H 0 3C,6GWILD OATS 4C,8H 4C,9H 4C,8H 4C,9H 4C,8H 3C,8H 4C,8G 0 6GWHEAT 9H 10H 3C,9H 5C,9H 4C,9H 9H 9H 0 8GCORN 3C,9G 9H 4C,9G 9H 5C,9G 4C,9G 9H 0 3C,7GSOYBEAN 3C,8H 9H 9H 9H 3C,8H 9H 9H 0 2C,4GRICE 10H 10E 4C,9G 10E 9G 10E 9H 2G 8HSORGHUM 3C,7H 9H 3C,9G 5C,9H 3C,8H 9H 3C,9H 0 0CHEATGRASS 9C 10E 4C,9H 9H 3C,9H 3C,9H 9H 0 6GSUGAR BEETS 9C 9G 7H 9C 3C,7G 3C,8G 8G 2H 5GVELVETLEAF 1C,2H 8G 1C 3C,6G 2C,2G 3C,7G 4C,9G 0 0GIANT FOXTAIL 5C,9G 9H 4C,9H 9H 4C,9H 9H 9H 0 2C,4GBARLEY 3C,9G 4C,9H 3C,9G 4C,9G 9H 9H 3C,9G 0 2C,2G__________________________________________________________________________
Test B
Postemergence
Three round pans (25 cm diameter by 12.5 cm deep) were filled with Sassafras sandy loam soil. One pan was planted with nutsedge (Cyperus rotundus) tubers, crabgrass (Digitaria sanguinalis), sicklepod (Cassia obtusifolia), jimsonweed (Datura stramonium), velvetleaf (Abutilon theophrasti), lambsquarters (Chenopodium album), rice (Oryza sativa), and teaweed (Sida spinosa). The second pot was planted with green foxtail (Setaria viridis), cocklebur (Xanthium pensylvanicum), morningglory (Ipomoea hederacea), cotton (Gossypium hirsutum), johnsongrass (Sorghum halepense), barnyardgrass (Echinochloa crus-qalli), corn (Zea mays), soybean (Glycine max), and giant foxtail (Setaria faberi). The third pot was planted with wheat (Triticum aestivum), barley (Hordeum vulgare), wild buckwheat (Polygonum convolvulus L.), cheatgrass (Bromus secalinus L.), sugarbeet (Beta arvensis), blackgrass (Alopecurus myosuroides), and rape (Brassica napus). The plants were grown for approximately fourteen days, then sprayed postemergence with the chemicals dissolved in a nonphytotoxic solvent.
Preemergence
Three round pans (25 cm diameter by 12.5 cm deep) were filled with Sassafras sand loam soil. One pan was planted with nutsedge tubers, crabgrass, sicklepod, jimsonweed, velvetleaf, lambsquarters, rice, and teaweed. The second pot was planted with green foxtail, cocklebur, morningglory, cotton, johnsongrass, barnyardgrass, corn, soybean, and giant foxtail. The third pot was planted with wheat, barley, wild buckwheat, cheatgrass, sugarbeet, wild oat, viola, blackgrass, and rape. The three pans were sprayed preemergence with the chemicals dissolved in a non-phytotoxic solvent.
Treated plants and controls were maintained in the greenhouse for approximately 24 days, then all rated plants were compared to controls and visually rated for plant response.
Response ratings are based on a scale of 0 to 100 where 0=no effect, and 100=complete control. A dash (-) response means no test.
Response ratings are contained in Table B.
TABLE B______________________________________ CMPD 7RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 30 50 70 100VELVETLEAF 0 0 30 60SUGAR BEETS 0 70 100 100CRABGRASS 0 30 50 70TEAWEED 0 30 50 70JIMSONWEED 30 50 70 90RICE 30 60 100 100COCKLEBUR 30 50 70 100COTTON 0 0 20 40SOYBEAN 50 80 100 100BARNYARD GRASS 30 60 100 100WILD OATS 30 60 90 100MORNINGGLORY 0 0 0 40WHEAT 40 60 80 100CASSIA 0 30 60 90JOHNSONGRASS 30 60 90 100NUTSEDGE 0 30 60 100CORN 70 80 100 100WILD BUCKWHEAT 30 40 50 70BLACK GRASS 30 50 70 100RAPESEED 30 50 60 70BARLEY 30 50 70 100GREEN FOXTAIL 0 30 60 100CHEAT GRASS 30 60 80 100VIOLA 70 100 100 100LAMBSQUARTER 50 70 100 100______________________________________ CMPD 7RATE RATE = G/HA 0016 0062 0250______________________________________PREEMERGENCEGIANT FOXTAIL 0 0 30VELVETLEAF 0 0 30SUGAR BEETS 30 50 70CRABGRASS 0 0 0TEAWEED 0 0 30JIMSONWEED 0 0 30RICE 0 30 80COCKLEBUR 0 0 30COTTON 0 0 0SOYBEAN 0 0 0BARNYARD GRASS 0 0 40WILD OATS 0 0 0MORNINGGLORY 0 0 0WHEAT 0 0 0CASSIA 0 30 60JOHNSONGRASS 0 30 70NUTSEDGE 0 0 0CORN 0 0 0WILD BUCKWHEAT 0 30 60BLACK GRASS 0 30 60RAPESEED 30 50 70BARLEY 0 0 0GREEN FOXTAIL 0 0 30CHEAT GRASS 0 30 50VIOLA 0 30 50LAMBSQUARTER 0 50 70______________________________________ CMPD 8RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 0 30VELVETLEAF 30 60 90 100SUGAR BEETS 30 50 80 100CRABGRASS 0 30 50 70TEAWEED 30 50 70 90JIMSONWEED 30 50 70 100RICE 30 50 70 90COCKLEBUR 30 60 90 100COTTON 0 40 80 100SOYBEAN 60 90 100 100BARNYARD GRASS 0 40 70 100WILD OATS 0 0 0 0MORNINGGLORY 0 30 60 100WHEAT 60 70 80 90CASSIA 30 60 90 100JOHNSONGRASS 30 50 70 100NUTSEDGE 0 0 50 70CORN 50 60 70 80WILD BUCKWHEAT 0 0 0 60BLACK GRASS 0 30 70 100RAPESEED 100 100 100 100BARLEY 30 50 70 90GREEN FOXTAIL 0 0 30 60CHEAT GRASS 30 50 70 100VIOLA 0 30 60 100LAMBSQUARTER 0 30 50 70______________________________________ CMPD 8RATE RATE = G/HA 0016 0062 0250______________________________________PREEMERGENCEGIANT FOXTAIL 0 30 50VELVETLEAF 0 30 60SUGAR BEETS 50 70 90CRABGRASS 30 50 70TEAWEED 0 30 70JIMSONWEED 0 30 60RICE 50 70 90COCKLEBUR 0 30 80COTTON 0 30 50SOYBEAN 0 30 50BARNYARD GRASS 0 30 60WILD OATS 0 0 30MORNINGGLORY 0 0 50WHEAT 30 50 70CASSIA 30 50 70JOHNSONGRASS 30 70 90NUTSEDGE 0 50 70CORN 0 30 60WILD BUCKWHEAT 30 50 80BLACK GRASS 50 70 90RAPESEED 50 70 90BARLEY 20 30 70GREEN FOXTAIL 0 30 70CHEAT GRASS 30 60 90VIOLA 50 70 90LAMBSQUARTER 0 50 100______________________________________ CMPD 9RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 0 0VELVETLEAF 0 30 70 100SUGAR BEETS 0 0 0 0CRABGRASS 0 0 0 30TEAWEED 0 0 30 60JIMSONWEED 0 0 0 30RICE 0 30 50 70COCKLEBUR 0 0 30 50COTTON 0 30 40 60SOYBEAN 0 0 20 40BARNYARD GRASS 0 0 0 0WILD OATS 0 0 0 0MORNINGGLORY 0 0 0 0WHEAT 0 0 30 50CASSIA 0 30 50 80JOHNSONGRASS 0 0 0 30NUTSEDGE 0 0 0 30CORN 0 0 0 30WILD BUCKWHEAT 0 0 0 0BLACK GRASS 0 0 0 0RAPESEED 50 70 100 100BARLEY 0 0 0 30GREEN FOXTAIL 0 0 0 30CHEAT GRASS 0 0 0 30VIOLA 0 0 0 30LAMBSQUARTER 0 0 0 0______________________________________ CMPD 9RATE RATE = G/HA 0016 0062 0250______________________________________PREEMERGENCEGIANT FOXTAIL 0 0 0VELVETLEAF 0 0 0SUGAR BEETS 0 30 50CRABGRASS 0 30 60TEAWEED 0 0 30JIMSONWEED 0 0 30RICE 0 30 60COCKLEBUR 0 0 30COTTON 0 0 0SOYBEAN 0 0 0BARNYARD GRASS 0 0 0WILD OATS 0 0 0MORNINGGLORY 0 0 0WHEAT 0 0 0CASSIA 0 0 30JOHNSONGRASS 0 0 40NUTSEDGE 0 0 0CORN 0 0 0WILD BUCKWHEAT 0 0 0BLACK GRASS 0 30 50RAPESEED 0 30 60BARLEY 0 0 0GREEN FOXTAIL 0 0 0CHEAT GRASS 0 0 0VIOLA 0 30 50LAMBSQUARTER 0 0 30______________________________________ CMPD 10RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 30 60 100VELVETLEAF 30 50 70 100SUGAR BEETS 0 0 0 0CRABGRASS 0 30 50 70TEAWEED 0 0 30 60JIMSONWEED 30 50 70 100RICE 30 50 70 100COCKLEBUR 30 60 90 100COTTON 0 30 50 70SOYBEAN 0 30 50 70BARNYARD GRASS 0 30 60 100WILD OATS 0 30 60 90MORNINGGLORY 30 50 70 100WHEAT 30 50 70 100CASSIA 0 30 50 80JOHNSONGRASS 30 50 70 100NUTSEDGE 0 0 40 100CORN 0 0 20 40WILD BUCKWHEAT 0 0 30 60BLACK GRASS 0 0 30 60RAPESEED 70 100 100 100BARLEY 0 0 30 70GREEN FOXTAIL 30 50 70 100CHEAT GRASS 0 0 0 0VIOLA 0 0 30 60LAMBSQUARTER 30 40 50 70______________________________________ CMPD 10RATE RATE = G/HA 0016 0062 0250______________________________________PREEMERGENCEGIANT FOXTAIL 0 30 60VELVETLEAF 0 0 30SUGAR BEETS 0 30 60CRABGRASS 0 30 50TEAWEED 0 30 70JIMSONWEED 0 0 30RICE 30 60 90COCKLEBUR 0 30 60COTTON 0 30 50SOYBEAN 0 0 0BARNYARD GRASS 0 0 30WILD OATS 0 0 30MORNINGGLORY 0 0 30WHEAT 0 0 30CASSIA 0 30 50JOHNSONGRASS 0 30 60NUTSEDGE 0 0 0CORN 0 0 0WILD BUCKWHEAT 0 30 60BLACK GRASS 0 0 50RAPESEED 30 50 70BARLEY 0 0 40GREEN FOXTAIL 0 30 60CHEAT GRASS 0 0 0VIOLA 30 50 70LAMBSQUARTER 30 60 90______________________________________ CMPD 11RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 30 60VELVETLEAF 30 50 70 100SUGAR BEETS 0 30 60 100CRABGRASS 0 30 50 70TEAWEED 30 50 70 90JIMSONWEED 30 50 70 100RICE 50 70 100 100COCKLEBUR 30 60 100 100COTTON 30 60 100 100SOYBEAN 70 80 90 100BARNYARD GRASS 30 50 70 100WILD OATS 0 0 0 30MORNINGGLORY 30 50 100 100WHEAT 30 50 70 100CASSIA 50 70 80 90JOHNSONGRASS 30 60 90 100NUTSEDGE 0 30 50 70CORN 30 50 100 100WILD BUCKWHEAT 0 0 30 70BLACK GRASS 0 30 60 90RAPESEED 90 100 100 100BARLEY 0 30 50 70GREEN FOXTAIL 0 0 30 60CHEAT GRASS 50 70 100 100LAMBSQUARTER 0 30 50 70______________________________________ CMPD 11 RATE RATE = G/HA 0016 0062 0250______________________________________PREEMERGENCEGIANT FOXTAIL 30 50 70VELVETLEAF 30 50 70SUGAR BEETS 50 70 90CRABGRASS 30 50 80TEAWEED 50 70 90JIMSONWEED 0 30 50RICE 70 90 100COCKLEBUR 50 70 90COTTON 30 50 70SOYBEAN 0 30 60BARNYARD GRASS 30 50 70WILD OATS 0 30 50MORNINGGLORY 0 30 70WHEAT 30 60 80CASSIA 30 50 80JOHNSONGRASS 50 70 90NUTSEDGE 30 50 90CORN 0 30 80WILD BUCKWHEAT 30 60 80BLACK GRASS 50 70 90RAPESEED 50 70 90BARLEY 0 30 70GREEN FOXTAIL 30 60 90CHEAT GRASS 30 50 80VIOLA 70 90 100LAMBSQUARTER 0 50 100______________________________________ CMPD 12RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 0 30VELVETLEAF 30 50 70 100SUGAR BEETS 0 0 0 0CRABGRASS 0 0 30 50TEAWEED 0 0 30 60JIMSONWEED 0 0 30 60RICE 0 30 50 70COCKLEBUR 0 30 60 90COTTON 0 30 60 90SOYBEAN 0 30 50 70BARNYARD GRASS 0 0 30 50WILD OATS 0 0 0 0MORNINGGLORY 0 30 30 50WHEAT 0 0 30 50CASSIA 30 40 60 80JOHNSONGRASS 0 0 0 30NUTSEDGE 0 0 0 0CORN 0 0 30 60WILD BUCKWHEAT 0 0 30 50BLACK GRASS 0 0 0 30RAPESEED 50 100 100 100BARLEY 0 0 0 30GREEN FOXTAIL 0 0 30 60CHEAT GRASS 0 0 30 50VIOLA 0 0 0 0LAMBSQUARTER 0 0 0 40______________________________________ CMPD 12RATE RATE = G/HA 0016 0062 0250______________________________________PREEMERGENCEGIANT FOXTAIL 0 0 30VELVETLEAF 0 0 30SUGAR BEETS 0 0 40CRABGRASS 0 30 50TEAWEED 0 0 40JIMSONWEED 0 0 30RICE 30 50 90COCKLEBUR 0 30 50COTTON 0 0 0SOYBEAN 0 0 0BARNYARD GRASS 0 30 60WILD OATS 0 0 0MORNINGGLORY 0 0 0WHEAT 0 0 30CASSIA 0 0 30JOHNSONGRASS 0 30 60NUTSEDGE 0 30 50CORN 0 0 0WILD BUCKWHEAT 0 30 60BLACK GRASS 30 60 80RAPESEED 30 50 70BARLEY 0 0 30GREEN FOXTAIL 0 0 30CHEAT GRASS 0 0 0VIOLA 90 100 100LAMBSQUARTER 0 30 60______________________________________ CMPD 13RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 30 60VELVETLEAF 0 0 50 100SUGAR BEETS 0 0 50 70CRABGRASS 0 30 50 70TEAWEED 30 50 70 90JIMSONWEED 0 30 50 70RICE 50 70 100 100COCKLEBUR 0 50 90 100COTTON 0 30 50 90SOYBEAN 70 100 100 100BARNYARD GRASS 30 60 100 100WILD OATS 0 30 50 70MORNINGGLORY 0 0 0 50WHEAT 30 50 70 100CASSIA 30 60 90 70JOHNSONGRASS 30 50 70 90NUTSEDGE 30 60 100 100CORN 80 90 100 100WILD BUCKWHEAT 0 0 0 30BLACK GRASS 0 30 60 90RAPESEED 50 100 100 100BARLEY 0 0 30 60GREEN FOXTAIL 0 30 50 70CHEAT GRASS 30 60 100 100VIOLA 50 70 100 100LAMBSQUARTER 60 80 90 100______________________________________ CMPD 13RATE RATE = G/HA 0016 0062 0250______________________________________PREEMERGENCEGIANT FOXTAIL 0 0 30VELVETLEAF 30 50 70SUGAR BEETS 30 50 60CRABGRASS 30 50 70TEAWEED 30 50 70JIMSONWEED 0 30 50RICE 50 70 90COCKLEBUR 30 50 70COTTON 0 30 60SOYBEAN 0 0 60BARNYARD GRASS 0 30 60WILD OATSMORNINGGLORY 0 0 0WHEAT 0 0 0CASSIA 0 30 50JOHNSONGRASS 30 60 90NUTSEDGE 0 40 60CORN 0 0 0WILD BUCKWHEAT 0 30 50BLACK GRASSRAPESEEDBARLEY 0 0 0GREEN FOXTAIL 0 30 50CHEAT GRASS 0 30 50LAMBSQUARTER 50 70 90______________________________________ CMPD 14RATE RATE = G/HA 0062______________________________________PREEMERGENCEGIANT FOXTAIL 0VELVETLEAF 0SUGAR BEETS 0CRABGRASS 0TEAWEED 0JIMSONWEED 40RICE 0COCKLEBUR 0COTTON 0SOYBEAN 0BARNYARD GRASS 0WILD OATS 0MORNINGGLORY 20WHEAT 40JOHNSONGRASS 20NUTSEDGE 0CORN 0WILD BUCKWHEAT 0BLACK GRASS 0RAPESEED 0BARLEY 0GREEN FOXTAIL 20CHEAT GRASS 0VIOLA 0LAMBSQUARTER 0______________________________________ CMPD 14RATE RATE = G/HA 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0VELVETLEAF 0SUGAR BEETS 50CRABGRASS 0TEAWEED 0JIMSONWEED 30RICE 0COCKLEBUR 30SOYBEAN 0BARNYARD GRASS 0WILD OATS 20MORNINGGLORY 20WHEAT 0CASSIA 0JOHNSONGRASS 0NUTSEDGE 0CORN 0WILD BUCKWHEAT 0BLACK GRASS 30RAPESEED 50BARLEY 0GREEN FOXTAIL 0CHEAT GRASS 0VIOLA 30LAMBSQUARTER 0______________________________________ CMPD 16RATE RATE = G/HA 0016 0062 0250 0500______________________________________PREEMERGENCEGIANT FOXTAIL 30 50 70 90VELVETLEAF 0 0 30 30SUGAR BEETS 30 50 70 100CRABGRASS 0 30 50 70TEAWEED 0 30 50 70JIMSONWEED 0 0 20 50RICE 30 60 90 100COCKLEBUR 0 20 30 50COTTON 0 0 30 60SOYBEAN 0 20 30 50BARNYARD GRASS 0 0 30 60WILD OATS 0 0 0 30MORNINGGLORY 0 10 20 30WHEAT 0 30 50 70CASSIA 0 0 30 50JOHNSONGRASS 0 30 60 90NUTSEDGE 0 0 30 70CORN 0 0 0 20WILD BUCKWHEAT 0 0 0 0BLACK GRASS 30 50 70 90RAPESEED 0 30 60 90BARLEY 0 20 30 60GREEN FOXTAIL 20 40 60 80CHEAT GRASS 0 30 50 70BUCKWHEATVIOLA 0 0 30 50LAMBSQUARTER 0 0 30 50CHICK WEED______________________________________ CMPD 16RATE RATE = G/HA 0016 0062 0250 0500______________________________________POSTEMERGENCEGIANT FOXTAIL 40 40 70VELVETLEAF 0 0 0 20SUGAR BEETS 10 10 30 70CRABGRASS 0 0 0 60TEAWEED 0 0 20 60JIMSONWEED 0 0 50 90RICE 50 60 80COCKLEBUR 30 40 40 60COTTON 0 0 10 20SOYBEAN 10 50 60 70BARNYARD GRASS 40 80 80WILD OATS 0 0 10MORNINGGLORY 0 0 0 0WHEAT 10 40 60 100CASSIA 0 0 40 50JOHNSONGRASS 60 70 70NUTSEDGE 0 0 40 50CORN 50 100WILD BUCKWHEAT 0 0 0 0BLACK GRASS 40 50 80RAPESEED 0 10 10 70BARLEY 0 0 0 10GREEN FOXTAIL 80 80 90CHEAT GRASS 0 0 40 40BUCKWHEATVIOLA 20 30 50 90LAMBSQUARTER 0 20 50 80CHICK WEED______________________________________ CMPD 17RATE RATE = G/HA 0016 0062 0250 0500______________________________________PREEMERGENCEGIANT FOXTAIL 0 0 0 20VELVETLEAF 0 0 20 30SUGAR BEETS 0 0 0 10CRABGRASS 0 0 0 0TEAWEED 40 50 0 0JIMSONWEED 0 0 30 30RICE 0 0 0 0COCKLEBUR 0 0 0 20COTTON 0 10 10 20SOYBEAN 0 0 0 10BARNYARD GRASS 0 0 0 20WILD OATS 0 0 0 0MORNINGGLORY 0 0 0 0WHEAT 0 0 0 0JOHNSONGRASS 0 0 0 0NUTSEDGE 0 0 30 60CORN 0 0 0 10BLACK GRASS 0 0 0 10RAPESEED 0 0 10 20BARLEY 0 0 0 0GREEN FOXTAIL 30 30 40 50CHEAT GRASS 10 30 40 40VIOLA 0 0 0 0LAMBSQUARTER 0 20 30 70______________________________________ CMPD 17RATE RATE = G/HA 0004 0016 0062 0250 0500______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 0 0 30VELVETLEAF 0 0 20 30 30SUGAR BEETS 0 0 0 30 50CRABGRASS 0 0 0 0 0TEAWEED 0 20 30 30 40JIMSONWEED 0 0 0 30 70RICE 0 0 0 0 0COCKLEBUR 0 0 30 40 70COTTON 0 0 0 20 30SOYBEAN 0 0 0 0 0BARNYARD GRASS 0 0 0 30 40WILD OATS 0 0 0 0 0MORNINGGLORY 0 0 0 0 50WHEAT 0 0 0 0 0CASSIA 0 0 20 30 60JOHNSONGRASS 0 20 40 40 40NUTSEDGE 0 0 0 0 0CORN 0 0 0 0 0WILD BUCKWHEAT 0 0 0 0BLACK GRASS 0 0 0 30 50RAPESEED 0 0 60 80 90BARLEY 0 0 0 0 0GREEN FOXTAIL 0 0 0 30 40CHEAT GRASS 0 0 0 0 0VIOLA 0 0 0 30 60LAMBSQUARTER 0 0 0 0 0______________________________________ CMPD 19RATE RATE = G/HA 0016 0062 0250 0500______________________________________PREEMERGENCEGIANT FOXTAIL 0 20 40 40VELVETLEAF 0 30 30SUGAR BEETS 20 40CRABGRASS 0 40 70 80TEAWEED 40 80 80JIMSONWEED 40 50 80RICE 0 20 80 90COCKLEBUR 0 0 40 40COTTON 0 10 20SOYBEAN 0 0 10 20BARNYARD GRASS 0 0 0 20WILD OATS 0 10 30 50MORNINGGLORY 30 40 50 50WHEAT 0 0 20 20JOHNSONGRASS 0 30 60 90NUTSEDGE 20 80CORN 0 10 70 70WILD BUCKWHEAT 20 70 80BLACK GRASS 30 40 70 90RAPESEED 0 10 80 90BARLEY 0 0 10 30GREEN FOXTAIL 0 20 60 90CHEAT GRASS 0 20 30 30VIOLA 0 20 50 70LAMBSQUARTER 40 80 90 100______________________________________ CMPD 19RATE RATE = G/HA 0004 0016 0062 0250 0500______________________________________POSTEMERGENCEGIANT FOXTAIL 0 20 20 20 30VELVETLEAF 20 30 30 30 30SUGAR BEETS 0 0 0 50 50CRABGRASS 0 0 0 0 30TEAWEED 0 30 70 70JIMSONWEED 0 40 60 70 70RICE 30 30COCKLEBUR 0 30 70 90 90COTTON 20 50 50 70 70SOYBEAN 70 70 80 80 80BARNYARD GRASS 0 0 0 0 20WILD OATS 50 50 50 50 60MORNINGGLORY 20 40 40 70 75WHEAT 0 0 0 20 20CASSIA 20 30 40 50 50JOHNSONGRASS 0 50 50 60 60NUTSEDGE 0 20 30 40 60CORN 70 80 80 80 80WILD BUCKWHEAT 0 0 50 50 60BLACK GRASS 0 40 40 40 60RAPESEED 60 80 90 90 90BARLEY 0 20 30 30 30GREEN FOXTAIL 0 20 30 40 50CHEAT GRASS 50 50 50 60 70VIOLA 0 0 50 50 80LAMBSQUARTER 0 30 30 50 60______________________________________ CMPD 23RATE RATE = G/HA 0016 0062 0250 0500______________________________________PREEMERGENCEGIANT FOXTAIL 0 0 0 0VELVETLEAF 0 0 20SUGAR BEETS 0 10 10 20CRABGRASS 0 0 0 20TEAWEED 0 0 30 40JIMSONWEED 0 0 0 0RICE 0 0 0 10COCKLEBUR 0 20 20COTTON 0 0 10SOYBEAN 0 0 0 0BARNYARD GRASS 0 0 0 0WILD OATS 0 0 0 20MORNINGGLORY 0 20 30 40WHEAT 0 0 0 40JOHNSONGRASS 0 0 0 20NUTSEDGE 0 0 0 30CORN 0 0 10 20WILD BUCKWHEAT 20 30 60 80BLACK GRASS 0 0 0 20RAPESEED 20 20 30 70BARLEY 0 0 0 20GREEN FOXTAIL 0 0 20 30CHEAT GRASS 0 10 30VIOLA 0 0 0 0LAMBSQUARTER 40 40 60______________________________________ CMPD 23RATE RATE = G/HA 0004 0016 0062 0250 0500______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 0 0 30VELVETLEAF 0 0 0 20 30SUGAR BEETS 0 0 50 50 50CRABGRASS 0 0 0 0 0TEAWEED 0 0 30 30 40JIMSONWEED 30 50 80 80 80RICE 0 0 0 0 0COCKLEBUR 0 0 0 0 40COTTON 0 0 0 0 0SOYBEAN 50 50 60 60 60BARNYARD GRASS 30 50 60 50 50WILD OATS 30 30 30 30 30MORNINGGLORY 0 0 0 0 0WHEAT 0 30 80 40 40CASSIA 0 0 0 20 30JOHNSONGRASS 30 50 60 50 50NUTSEDGE 0 0 0 30 30CORN 60 60 60 50 50WILD BUCKWHEAT 0 0 0 0 0BLACK GRASS 0 0 0 0 0RAPESEED 40 40 40 60 60BARLEY 0 0 0 0 0GREEN FOXTAIL 0 0 0 0 0CHEAT GRASS 0 0 30 30 30VIOLA 0 0 30 30 30LAMBSQUARTER 0 20 30 30 30______________________________________ CMPD 24RATE RATE = G/HA 0004 0016 0062 0250______________________________________PREEMERGENCEGIANT FOXTAIL 20 30 60 100VELVETLEAF 0 30 40 90SUGAR BEETS 70 80 90 100CRABGRASS 0 0 50 70TEAWEED 20 70 70 80JIMSONWEED 0 20 40 90RICE 70 80 90 100COCKLEBUR 20 40 50 80COTTON 0 0 40 90SOYBEAN 0 0 20 70BARNYARD GRASS 0 10 50 90WILD OATS 0 20 50 80MORNINGGLORY 30 40 40 50WHEAT 10 10 40 50JOHNSONGRASS 0 30 50 90NUTSEDGE 60 80 90 100CORN 0 10 70 90WILD BUCKWHEAT 70 70 80 90BLACK GRASS 30 70 80 90RAPESEED 20 80 90 100BARLEY 0 20 40 50GREEN FOXTAIL 0 30 70 100CHEAT GRASS 40 50 50 80VIOLA 20 50 70 100LAMBSQUARTER 40 60 80 90______________________________________ CMPD 24RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 30VELVETLEAF 0 0 0 60SUGAR BEETS 0 80 80 80CRABGRASS 0 0 20 40TEAWEED 0 20 30 70JIMSONWEED 0 0 20 30RICE 0 20 40 40COCKLEBUR 0 20 40 70COTTON 0 20 20 50SOYBEAN 0 30 40 70BARNYARD GRASS 0 0 0 40WILD OATS 0 0 0 40MORNINGGLORY 0 0 20 30WHEAT 0 0 0 30CASSIA 0 0 20 30JOHNSONGRASS 0 0 0 80NUTSEDGE 0 0 30 50CORN 0 20 30 70WILD BUCKWHEAT 0 0 0 50BLACK GRASS 0 0 20 30RAPESEED 0 40 80 90BARLEY 0 0 0 30GREEN FOXTAIL 0 0 30 70CHEAT GRASS 0 0 0 40VIOLA 0 0 0 30LAMBSQUARTER 0 30 40 50______________________________________ CMPD 27RATE RATE = G/HA 0062 0125 0250 0500______________________________________POSTEMERGENCEGIANT FOXTAIL 0 0 30 40VELVETLEAF 0 0 0 20SUGAR BEETS 0 0 0 30CRABGRASS 0 0 20 50TEAWEED 0 30 30 30JIMSONWEED 0 0 0 30RICE 0 0 20 20COCKLEBUR 0 0 30 40COTTON 0 0 0 0SOYBEAN 0 20 20 50BARNYARD GRASS 0 30 30 40WILD OATS 0 0 0 0MORNINGGLORY 0 0 0 20WHEAT 0 0 0 20CASSIA 0 0 0 0JOHNSONGRASS 0 0 0 0NUTSEDGE 0 0 0 50CORN 0 30 40 60WILD BUCKWHEAT 0 0 0 0BLACK GRASS 0 40 50 60RAPESEED 0 0 0 0BARLEY 0 0 0 0GREEN FOXTAIL 0 0 30 50CHEAT GRASS 0 30 30 40VIOLA 0 0 0 0LAMBSQUARTER 0 0 0 0______________________________________ CMPD 27RATE RATE = G/HA 0062 0125 0250 0500______________________________________PREEMERGENCEGIANT FOXTAIL 0 0 0VELVETLEAF 0 0 0 40SUGAR BEETS 0 0 0CRABGRASS 0 0 0 0TEAWEED 0 0 0 50JIMSONWEED 0 0 0 40RICE 0 0 0 0COCKLEBUR 0 0 0 50COTTON 0 0 0 0SOYBEAN 0 0 20BARNYARD GRASS 0 0 0 0WILD OATS 0 0 0MORNINGGLORY 0 0 0 20WHEAT 0 0 0CASSIA 0 0 0 0JOHNSONGRASS 0 0 0 20NUTSEDGE 0 0 0 0CORN 0 0 0WILD BUCKWHEAT 0 0 0BLACK GRASS 0 0 20RAPESEED 0 0 0BARLEY 0 0 0GREEN FOXTAIL 0 0 0 40CHEAT GRASS 0 0 20VIOLA 0 0 0LAMBSQUARTER 0 0 0 0______________________________________ CMPD 35RATE RATE = G/HA 0016 0062 0250 0500______________________________________PREEMERGENCEGIANT FOXTAIL 0 0 0 20VELVETLEAF 0 40 50 50SUGAR BEETS 10 20 60 70CRABGRASS 0 0 30 70TEAWEED 0 30 70 80JIMSONWEED 0 30 80 90RICE 0 30 80 80COCKLEBUR 20 30 50COTTON 0 10 20 40SOYBEAN 0 0 0 30BARNYARD GRASS 0 0 30 30WILD OATS 0 10 50 50MORNINGGLORY 0 20 30 40WHEAT 10 30 50 60JOHNSONGRASS 20 50 60 70NUTSEDGE 30 70 90 90CORN 0 60 90WILD BUCKWHEAT 20 60 60BLACK GRASS 30 40 50 70RAPESEED 40 40 50 80BARLEY 0 0 0 10GREEN FOXTAIL 0 20 30 50CHEAT GRASS 20 50 70 80VIOLA 0 40 60 80LAMBSQUARTER 40 40 80 100______________________________________ CMPD 35RATE RATE = G/HA 0001 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 20 30 30VELVETLEAF 0 20 50 80SUGAR BEETS 0 0 20 80CRABGRASS 0 0 0 20TEAWEED 0 0 20 70JIMSONWEED 0 80RICE 20 30 40 40COCKLEBUR 0 0 30 70COTTON 0 0 0 20SOYBEAN 50 60 70 90BARNYARD GRASS 0 20 60 70WILD OATS 0 20 40 70MORNINGGLORY 0 0 0 30WHEAT 0 30 50 90CASSIA 0 20 30 30JOHNSONGRASS 50 50 70 70NUTSEDGE 0 20 30 50CORN 60 70 90 100WILD BUCKWHEAT 0 0 0 30BLACK GRASS 0 0 30 50RAPESEED 0 0 60 100BARLEY 0 0 20 30GREEN FOXTAIL 0 0 30 30CHEAT GRASS 0 0 40 50VIOLA 0 0 50 80LAMBSQUARTER 0 30______________________________________ CMPD 41RATE RATE = G/HA 0062 0250 0500 1000______________________________________PREEMERGENCEGIANT FOXTAIL 0 50 70VELVETLEAF 20 30 50 70SUGAR BEETS 70 80 90 90CRABGRASS 0 0 20 30TEAWEED 0 0 0 0JIMSONWEED 0 0 20 30RICE 40 90 95 100COCKLEBUR 0 20 30COTTON 0 20 60 70SOYBEAN 30 80 90 90BARNYARD GRASS 30 60 70WILD OATS 0 0 40MORNINGGLORY 20 50 70 80WHEAT 0 0 50 60CASSIA 0 0 20 50JOHNSONGRASS 30 60 60 60NUTSEDGE 0 0 20 70CORN 0 0 40 50WILD BUCKWHEAT 50 80 80 90BLACK GRASS 0 70 70 100RAPESEED 80 80 100BARLEY 0 0 0 0GREEN FOXTAIL 0 20 30 70CHEAT GRASS 0 40 60 70VIOLA 0 0 0 50LAMBSQUARTER 50 60 80 90______________________________________ CMPD 41RATE RATE = G/HA 0016 0062 0250 0500 1000______________________________________POSTEMERGENCEGIANT FOXTAIL 0 30 40 60 60VELVETLEAF 30 40 80 90 100SUGAR BEETS 70 80 90 100 100CRABGRASS 30 40TEAWEED 50 60 70 70 90JIMSONWEED 0 30 50 60 50RICE 100 100COCKLEBUR 60 70 90 90COTTON 50 80 90 90 90SOYBEAN 70 80 100 100 100BARNYARD GRASS 20 60 70 70 70WILD OATS 60 70 80 90 90MORNINGGLORY 40 90 90 90 90WHEAT 40 50 50 60 60CASSIA 30 40 60 60JOHNSONGRASS 30 80 80 90NUTSEDGE 0 0 0 30 30CORN 0 0 0 0 10WILD BUCKWHEAT 0 0 50 80 90BLACK GRASS 30 70 90 90RAPESEED 80 90 100 100 100BARLEY 0 0 10 20GREEN FOXTAIL 0 50 70 70CHEAT GRASS 60 70 70 80 80VIOLA 0 0 0 0 30LAMBSQUARTER 40 70 80 80 100______________________________________ CMPD 50RATE RATE = G/HA 0016 0062______________________________________PREEMERGENCEGIANT FOXTAIL 0 10VELVETLEAF 0 0SUGAR BEETS 10 30CRABGRASS 0 0TEAWEED 30JIMSONWEED 0 0RICE 0 0COCKLEBUR 0 20COTTON 0SOYBEAN 0 10BARNYARD GRASS 0 0WILD OATS 0 0MORNINGGLORY 0 30WHEAT 0 0JOHNSONGRASS 0 0NUTSEDGE 0 0CORN 0 0WILD BUCKWHEAT 20 30BLACK GRASS 0 40RAPESEED 0 20BARLEY 0 20GREEN FOXTAIL 0 0CHEAT GRASS 0 30VIOLA 0 0LAMBSQUARTER 30 60______________________________________ CMPD 50RATE RATE = G/HA 0004 0016 0062______________________________________POSTEMERGENCEGIANT FOXTAIL 0 20 40VELVETLEAF 0 20 30SUGAR BEETS 0 20 70CRABGRASS 0 0 0TEAWEED 0 0 20JIMSONWEED 0 0 30RICE 0 30 30COCKLEBUR 40 50 80COTTON 0 0 0SOYBEAN 0 30 40BARNYARD GRASS 0 30 30WILD OATS 0 0 0MORNINGGLORY 0 0 30WHEAT 0 0 0CASSIA 0 0 0JOHNSONGRASS 0 30 40NUTSEDGE 0 20 30CORN 0 30 40WILD BUCKWHEAT 0 0 0BLACK GRASS 0 20 30RAPESEED 0 20 90BARLEY 0 0 0GREEN FOXTAIL 0 50 60CHEAT GRASS 0 20 30VIOLA 0 20 60LAMBSQUARTER 0______________________________________
Test C
The purpose of this screen is to identify and characterize potential sugarbeet herbicides.
Seeds of the following crops and weeds are sown into 18 cm diameter plastic pots containing steam-sterilized Sassafras sandy loam soil (0.8% organic soil, pH 6.7): spring wheat (Triticum gestivum), spring barley (Hordeum vulgare), sugarbeets (Beta vulgaris), black nightshade (Solanum nigrum), chickweed (Stellaria media), cleavers (Galium aparine), common lambsquarters (Chenopodium album), knotweed (Polygonum aviculare), kochia (Kochia scoparia), matricaria (Matricaria indora), redroot pigweed Amaranthus retroflexus), speedwell (Veronica persica), wild mustard (Sinapis arvensis), wild radish (Raphinus raphinistrum), smartweed (Polygonum pericaria), black bindweed (Polygonum convolvulus), annual bluegrass (Poa annua), annual ryegrass (Lolium multiflorum), blackgrass (Alopecurus myosuroides), green foxtail (Setaria viridis), and wild oats (Avena fatua).
The compound tested is formulated in a nonphytotoxic solvent and applied as a spray to the soil (preemergence) or to the foliage and soil (postemergence). Plants are treated at three stages: (1) preemergence, (2) postemergence when the sugarbeets are in the 1-2 leaf stage (Postemergence 1), and (3) postemergence when the sugarbeets are in the 3-4 leaf stage (Postemergence 2). Plants are grown in a temperature-controlled greenhouse for the duration of the experiment.
Weed control and crop injury are evaluated visually (38 days after the Pre treatment, 28 days after Post treatment 1, and 11 days after Post treatment 2). Ratings are expressed using a scale of 0 to 100, where 0 means no injury or control and 100 means complete death of the plants. The ratings are summarized in Table C.
TABLE C__________________________________________________________________________ CMPD 9 CMPD 10 CMPD 12__________________________________________________________________________RATE RATE GM/HA 0030 0063 0125 0250 0030 0063 0125 0250 0030 0063 0125 0250__________________________________________________________________________PREEMERGENCEWHEAT 0 20 20 25 20 45 50 80 0 25 30 65BARLEY 0 25 35 50 20 50 60 90 0 15 45 85BLCK NIGHTSHADE 20 0 20 20 20 65 90 95 20 20 20 20CHICK WEED 0 20 0 0 0 0 20 20 0 0 0 20LAMBSQUARTER 80 80 80 80 70 50 100 100 50 50 60 80GALIUM 0 50 50 100 100 100 100 100 20 20 60 100MATRA INDORA 0 0 0 0 35 80 100 100 0 30 20 75PIG WEED 20 0 20 20 0 20 30 20 30 20 25 35SMART WEED 25 0 20 20 0 90 80 100 0 20 100 0SPEEDWELL 30 35 25 30 0 0 20 0 25 20 20 30BUCKWHEAT 25 45 25 25 30 55 90 100 0 0 25 100MUSTARD 50 50 70 90 50 90 100 100 0 95 100 100WILD RADISH 0 20 50 50 0 70 95 100 50 60 50 95BLUE GRASS 0 0 20 50 0 60 75 90 0 15 50 80RYE GRASS 0 0 0 0 0 20 40 80 0 0 20 45BLACK GRASS 0 60 70 25 0 0 100 100 0 20 30 90GREEN FOXTAIL 20 50 20 20 30 65 80 80 0 0 20 20WILD OATS 0 0 30 0 50 35 20 80 0 0 20 50SUGARBEET C/TOL 40 20 40 25 0 25 40 10 0 10 25 10__________________________________________________________________________RATE RATE GM/HA 0016 0030 0063 0125 0016 0030 0063 0125 0016 0030 0063 0125__________________________________________________________________________ POSTEMERGENCE 1WHEAT 25 60 75 85 70 90 100 95 70 70 70 80BARLEY 25 60 80 80 70 80 90 95 30 70 85 80BLCK NIGHTSHADE 0 40 40 40 70 90 90 100 0 30 30 30CHICK WEED 30 0 30 20 25 25 25 0 0 0 0 0LAMBSQUARTER 20 0 0 0 70 80 80 90 30 0 0 50GALIUM 20 50 100 40 85 100 100 100 0 20 0 60MATRA INDORA 0 20 35 40 80 95 100 100 20 20 0 80PIG WEED 40 60 30 70 50 60 50 80 0 30 40 60SMART WEED 0 0 0 0 85 100 90 100 0 20 20 20SPEEDWELL 0 20 20 20 25 0 0 25 0 0 0 25BUCKWHEAT 0 30 30 30 70 80 90 100 30 20 20 70MUSTARD 100 100 100 100 100 100 100 100 100 100 100 100WILD RADISH 70 100 100 100 100 100 100 100 90 100 100 100BLUE GRASS 0 0 15 30 50 80 90 90 0 0 0 60RYE GRASS 20 20 30 60 0 100 95 100 20 40 40 60BLACK GRASS 0 0 20 90 50 95 100 100 20 80 80 100GREEN FOXTAIL 0 0 30 20 60 70 90 95 20 0 20 30WILD OATS 10 25 20 40 90 100 100 100 20 20 20 50SUGARBEET C/TOL 15 20 20 25 20 30 20 50 0 0 20 25__________________________________________________________________________RATE GM/HA 0016 0030 0063 0125 0016 0030 0063 0125 0063 0125__________________________________________________________________________ POSTEMERGENCE 2WHEAT 30 25 30 30 20 60 40 50 20 40BARLEY 35 45 30 25 30 50 50 40 20 50BLCK NIGHTSHADE 50 50 50 50 25 50 50 50 20 60CHICK WEED 80 80 85 90 60 50 65 80 20 25LAMBSQUARTER 0 20 20 20 30 50 50 50 0 30GALIUM 20 40 65 70 30 60 50 70 25 30MATRA INDORA 0 0 0 0 20 20 0 20 0 0PIG WEED 50 50 70 65 60 50 60 80 0 30SMART WEED 0 30 0 30 0 20 40 60 0 0SPEEDWELL 25 20 25 20 20 25 25 20 30 25BUCKWHEAT 0 30 70 80 30 50 50 50 0 25MUSTARD 70 70 60 85 60 50 90 30 30 80WILD RADISH 25 20 50 25 0 20 50 25 0 50BLUE GRASS 0 0 0 15 0 0 0 20 0 0RYE GRASS 0 15 25 35 50 35 20 10 30 70BLACK GRASS 25 50 30 70 40 20 50 80 20 40GREEN FOXTAIL 20 20 0 0 20 20 20 20 0 0WILD OATS 0 10 50 20 60 60 20 25 20 20SUGARBEET C/TOL 10 15 15 20 15 15 20 25 15 20KNOT WEEDKOCHIA__________________________________________________________________________
Test D
This test was conducted to evaluate compounds for potential utility in fallow weed control. This test was comprised of a preemergence segment and a postemergence segment. Both segments were conducted in 26 cm plastic pans containing pasteurized Sassafras sandy loam soil (pH 6.5, 1% organic matter). The postemergence fallow segment was planted in two parts with a separation of seven days between the first and second plantings. The common name, botanical name, and size at herbicide application are presented in the following tables.
______________________________________Common Name Botanical Name Size (cm)______________________________________Downy brome Bromus tectorum 7.0Kochia, Fireweed Kochia scoparia 3.0Russian thistle Salsoa kali 3.0Wild oats Avena fatua 6.0Field bindweed Convolvulus arvensis 4.0Cereal rye Secale cereale 7.0Green foxtail Setaria viridis 5.0Winter wheat Triticum aestivum 8.0______________________________________
The postemergence segment of the screen was grown in the greenhouse for approximately 18 days until treatment. The preemergence segment was planted immediately before herbicidal application using the following species.
______________________________________Common Name Botanical Name______________________________________Jointed goatgrass Aegilops cylindricaRedroot pigweed Amaranthus retroflexusWild oats Avena fatuaCommon lambsquarters Chenopodium albumField bindweed Convolvulus arvensisDowny brome Brome tectorumSpring barley Hordeum vulgareKochia, Fireweed Kochia scopariaWild buckwheat Polygonum convolvulusRussian thistle Salsoa kaliCereal rye Secale cerealeGreen foxtail Setaria viridisSorghum Sorghum bicolorSpring wheat Triticum aestivumWinter wheat Triticum aestivumCorn Zea mays______________________________________
All herbicides were applied to pots and plants using a belt sprayer with the compound dissolved in AGWT, a non-phytotoxic solvent system. All treatments were maintained in the greenhouse for 21 days at which time they were rated on a scale of 0 to 100 for each species (0=no control, 100=complete control). The response data are summarized in Table D. "Cheat grass" recited in this table was actually downy brome, a related Bromus species.
TABLE D______________________________________ CMPD 13RATE RATE = G/H 64. 125. 250. 500. 1000.______________________________________PREEMERGENCEWINE WHEAT 0 20 40 60 60RUSSIAN THSTL 0 0 0 20 40KOCHIA 20 50 60 80 100CHEAT GRASS 10 20 40 60 70GREEN FXTL 0 10 30 40 60WHEAT 40 60 90 90 90WILD OATS 0 0 30 50 70RYE 0 0 0 20 30BARLEY 30 50 70 90 90CORN 20 40 70 100 100SORGHUM 60 70 90 100 100FIELD BINDWEED 0 0 0 20 50JOINT GOATGRASS 0 0 20 30 40WILD BUCKWHEAT 0 0 30 50 70LAMBSQUARTER 40 60 70 70 90PIG WEED 20 30 80 80 90POSTEMERGENCERUSSIAN THISTLE 0 70 100 100 100KOCHIA 100 100 100 100 100CHEAT GRASS 90 90 90 90 90GREEN FOXTAIL 60 70 80 90 100WILD OATS 40 40 70 90 100WHEAT 90 90 100 100 100RYE 90 90 100 100 100FIELD BINDWEED 60 100 100 100 100______________________________________

	Number	Date
Parent	22279	Mar 1987
Parent	892062	Aug 1986
Parent	856511	Apr 1986

Heterocyclic acyl sulfonamides

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