Claims
- 1. A variant of HIV-3 retrovirus, comprising three core proteins with molecular weights of about 12 kD, about 17 kD, and about 25 kD, an endonuclease with molecular weight of about 31 kD, two reverse trascnriptases with molecular weights of about 49 kD and about 62 kD, a transmembrane protein with molecular weight of about 41 kD, and an outer membrane protein with molecular weight of about 120 kD, the variant characterized in that its RNA does not hybridize with RNA or DNA derived from either the Env gene, the LTR sequence, or the Pol region of the HIV-1 genome, under stringent conditions.
- 2. A variant of HIV-3 retrovirus, comprising three core proteins with molecular weights of about 12 kD, about 17 kD, and about 25 kD, an endonuclease with molecular weight of about 31 kD, two reverse transcriptases with molecular weights of about 49 kD and about 62 kD, a transmembrane protein with molecular weight of about 41 kD, and an outer membrane protein with molecular weight of about 120 kD, the variant characterized in that its LTR sequence is about 70% or less homologous to the LIR sequence of HIV-1 and less than 55% homologous to the LTR sequence of HIV-2.
Priority Claims (1)
Number |
Date |
Country |
Kind |
88 109 200 |
Jun 1988 |
EP |
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Parent Case Info
This is a continuation of application Ser. No. 08/900,902, filed Jul. 25, 1997, now issued as U.S. Pat. No. 6,013,484, which is a divisional of Ser. No. 08/486,836, filed Jun. 7, 1995, now issued as U.S. Pat. No. 5,795,743, which is a divisional of Ser. No. 08/228,519, filed Apr. 15, 1994, now issued as U.S. Pat. No. 5,567,603, which is a divisional of Ser. No. 07/460,913, filed Mar. 23, 1990, now issued as U.S. Pat. No. 5,304,466, which claims benefit under 35 U.S.C. §120 of PCT/EP89/00643, filed Jun. 8, 1989 and claims priority under 35 U.S.C. §119 of EP 88 109 200.1, filed Jun. 9, 1988.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
4839288 |
Montagnier |
Jun 1989 |
|
5066782 |
Montagnier et al. |
Nov 1991 |
|
5567603 |
De Leys et al. |
Oct 1996 |
|
Foreign Referenced Citations (2)
Number |
Date |
Country |
239425 |
Sep 1987 |
EP |
8602383 |
Apr 1986 |
WO |
Non-Patent Literature Citations (11)
Entry |
Rayfield et al., Emerging Infectious Diseases 2:209-212 (1996). |
Janssens et al., AIDS 8:1012-1013 (1994). |
Simon et al., AIDS 8:1628-1629 (1994). |
Gürtler et al., Journal of Virology 68:1581-1585 (1994). |
Vanden Haesevelde et al., Journal of Virology 68:1586-1596 (1994). |
Franchini et al., “Genetic Analysis of a New Subgroup of Human and Simian T-lymphotropic Retroviruses: HTLV-IV, LAV-2, SBL-6669, and STLV-IIIAGM,” AIDS Research and Human Retroviruses 23(1):11-17 (1987). |
Clavel et al., “Isolation of a New Human Retrovirus from West Africa Patients with AIDS,” Science 233:343-346 (1986). |
Clavel et al., “Molecular Cloning and Polymorphism of the Human Immune Deficiency Virus Type 2,” Nature 324(18):691-695 (1986). |
Guyader et al, “Genome Organization and Transactivation of the Human Immunodeficiency Virus Type 2,” Nature 326:662-669 (1987). |
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Continuations (1)
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Number |
Date |
Country |
Parent |
08/900902 |
Jul 1997 |
US |
Child |
09/379270 |
|
US |