Claims
- 1. A method of radiation therapy of a human or other mammalian patient, which comprises administering to the patient a radioactive particulate material comprising hollow or cup-shaped microspheres, said microspheres comprising a beta-radiation emitting radionuclide, and having a diameter in the range of from 5 to 200 microns wherein the microspheres consist of yttria or another yttrium-containing compound as base material and the radionuclide is yttrium-90.
- 2. A method according to claim 1, wherein the microspheres have a diameter in the range of from 20 to 80 microns.
- 3. A method according to claim 1, wherein the radiation therapy comprises treatment of cancer or tumours in the patient.
- 4. A method according to claim 3, wherein the radiation therapy comprises treatment of primary or secondary cancer of the liver of the patient.
- 5. A particulate material comprising hollow or cup-shaped microspheres having a diameter of from 5 to 200 microns, wherein the microspheres consist of yttria or another yttrium-containing compound as base material, produced by a process comprising the steps of:(a) forming an aggregate of powdered base material with a suitable binder; (b) thermal spraying of the aggregate to melt the base material and vaporize the binder to form the hollow or cup-shaped microspheres; (c) solidifying the molten hollow or cup-shaped microspheres.
- 6. A particulate material comprising hollow or cup-shaped microspheres which consist of yttria or another yttrium-containing compound as base material, said microspheres having a diameter of from 5 to 200 microns.
- 7. A radioactive particulate material comprising hollow or cup-shaped microspheres having a diameter in the range of from 5 to 200 microns and comprising a beta-radiation emitting radionuclide, wherein the microspheres consist of yttria or another yttrium-containing compound as base material and the radionuclide is yttrium-90, produced by a process comprising the steps of:(a) forming an aggregate of powdered base material with a suitable binder; (b) thermal spraying of the aggregate to melt the base material and vaporize the binder to form the hollow or cup-shaped microspheres; (c) solidifying the molten hollow or cup-shaped microspheres. (d) exposing the solidified hollow or cup-shaped microspheres to a neutron beam to activate the base material to the beta-radiation emitting radionuclide.
- 8. A radioactive particulate material comprising hollow or cup-shaped microspheres having a diameter in the range of from 5 to 200 microns and comprising a beta-radiation emitting radionuclide, wherein the microspheres consists of yttria or another yttrium-containing compound as base material and the radionuclide is yttrium-90.
Priority Claims (1)
Number |
Date |
Country |
Kind |
54724/94 |
Jan 1994 |
AU |
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Parent Case Info
This application is a continuation of Ser. No. 08/676,381 filed Sep. 23, 1996, now U.S. Pat. No. 5,885,547.
US Referenced Citations (17)
Foreign Referenced Citations (5)
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0182131 |
May 1986 |
EP |
0369638 |
May 1990 |
EP |
2073589 |
Oct 1981 |
GB |
WO8602093 |
Apr 1986 |
WO |
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Continuations (1)
|
Number |
Date |
Country |
Parent |
08/676381 |
Sep 1996 |
US |
Child |
09/178259 |
|
US |