Claims
- 1. A compound of the formula: ##STR5## wherein R.sup.2 is hydrogen, or lower alkyl which is unsubstituted or substituted by lower alkoxy, hydroxy, acyloxy, di(lower)alkylamino, pyridyl, imidazolyl or lower alkoxyphenyl,
- R.sup.3 is hydrogen, lower alkyl, lower alkoxy, or halogen,
- A is methylene and
- Q is a group of the formula:
- --CO--R.sup.1
- (in which R.sup.1 is lower alkyl, amino, acylamino, hydroxy(lower)alkyl, lower alkanoyloxy(lower)alkyl, lower alkoxy, amino(lower)alkyl, lower alkanoylamino(lower)alkyl, or lower alkoxycarbonylamino(lower)-alkyl), or
- carbamimidoyl which is substituted by cyano and lower alkyl, with the proviso that
- when Q is carbamimidoyl which is substituted by cyano and lower alkyl,
- then R.sup.3 is lower alkoxy.
- 2. A compound of claim 1, wherein
- R.sup.2 is lower alkyl which may be substituted by pyridyl, imidazolyl or lower alkoxyphenyl,
- R.sup.3 is hydrogen, lower alkyl, lower alkoxy, or halogen, and
- Q is a group of the formula:
- --CO13 R.sup.1
- wherein R.sup.1 is lower alkyl, amino, acylamino, hydroxy(lower)alkyl, acyloxy(lower)alkyl, lower alkoxy, amino(lower)alkyl or acylamino(lower)alkyl.
- 3. A compound of claim 2, wherein
- R.sup.2 is lower alkoxyphenyl (lower) alkyl,
- R.sup.3 is hydrogen, and
- Q is a group of the formula:
- --CO--R.sup.1
- wherein R.sup.1 is lower alkyl.
- 4. A pharmaceutical composition which comprises, as an active ingredient, a compound of claim 1 or a pharmaceutically acceptable salt thereof in admixture with pharmaceutically acceptable carriers.
- 5. A method for the prophylactic or therapeutic treatment of ulcer which comprises administering a compound of claim 1 or a pharmaceutically acceptable salt thereof to human or animals.
Priority Claims (1)
Number |
Date |
Country |
Kind |
9125970 |
Dec 1991 |
GBX |
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Parent Case Info
This is a continuation of application Ser. No. 07/978,477 filed on Nov. 18, 1992, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4315009 |
Jones |
Feb 1982 |
|
Continuations (1)
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Number |
Date |
Country |
Parent |
978477 |
Nov 1992 |
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