Claims
- 1. A hydrogel-forming system which comprises from 0.01 to 99.99% by weight of (A) a hydrophobic macromer with unsaturated group terminated ends which is prepared by reacting the hydroxyls of a diol obtained by converting hydroxy of terminal carboxylic acid group of aliphatic polyester to aminoethanol group, with an unsaturated group introducing compound, and from 99.99 to 0.01% by weight of (B) a hydrophilic polymer which is a polysaccharide containing hydroxy groups which are reacted with unsaturated group introducing compound; wherein (A) and (B) constitute different compounds from one another and the total of the percentages of(A) and (B) is 100%.
- 2. The hydrogel-forming system according to claim 2 wherein the hydrophobic macromer is prepared by reacting the hydroxyls of a diol obtained by converting hydroxy of terminal carboxylic acid group of aliphatic polyester to aminoethanol group, with an unsaturated group introducing compound.
- 3. The hydrogel-forming system according to claim 2 wherein the hydrophilic polymer is dextran wherein one or more hydroxyls in a glucose unit of the dextran is (are) reacted with an unsaturated group introducing compound.
- 4. The hydrogel-forming system according to claim 1 wherein the hydrophilic polymer is dextran-maleic acid monoester.
CROSS-REFERENCE TO RELATED APPLICATION
This application claims the benefit of U.S. Provisional Application No. 60/128,803, filed Apr. 12, 1999.
US Referenced Citations (19)
Foreign Referenced Citations (1)
Number |
Date |
Country |
WO 0012619 |
Mar 2000 |
WO |
Non-Patent Literature Citations (2)
Entry |
Kurisawa, M., et al., J. Biomater. Sci. Polymer Edn., vol. 8, No. 9; 691-708 (1997). |
Zhang, Y., et al., J. Polym. Sci., Polymer Chemistry 37, 4554-4569 (Dec. 15, 1999). |
Provisional Applications (1)
|
Number |
Date |
Country |
|
60/128803 |
Apr 1999 |
US |