Claims
- 1. A compound of the formula ##STR13## wherein R is hydroxy, amino or lower alkoxy;
- R.sub.1 and R.sub.4 each is hydrogen, lower alkyl or phenyl-lower alkyl;
- R.sub.3 is hydrogen, hydroxy or lower alkyl;
- m is 3;
- n is 0, 1 or 2
- and basic salts thereof.
- 2. A compound as in claim 1 wherein R is hydroxy; R.sub.1 is hydrogen or lower alkyl; R.sub.3 and R.sub.4 each is hydrogen; and n is 1 or 2.
- 3. A compound as in claim 1 wherein R.sub.3 and R.sub.4 each is hydrogen.
- 4. A compound as in claim 1 wherein n is 1.
- 5. A compound as in claim 1 wherein n is 2.
- 6. A compound as in claim 1 wherein R is hydroxy.
- 7. A compound as in claim 1 wherein R.sub.1 is hydrogen or methyl.
- 8. A compound as in claim 1 in which the pipecolic acid is in the L-form.
- 9. A compound as in claim 6 wherein R.sub.1 is methyl, R.sub.3 is hydrogen and n is 0.
- 10. A compound as in claim 6 wherein R.sub.1 is methyl, R.sub.3 and R.sub.4 each is hydrogen and n is 1.
- 11. A compound as in claim 6 wherein R.sub.1 is methyl, R.sub.3 and R.sub.4 each is hydrogen and n is 2.
- 12. A compound as in claim 6 wherein R.sub.1 is methyl, R.sub.3 is 5-hydroxy, R.sub.4 is hydrogen and n is 1.
- 13. A compound as in claim 6 wherein R.sub.1 is methyl, R.sub.3 is 5-hydroxy, R.sub.4 is hydrogen and n is 2.
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of application Ser. No. 768,003, filed Feb. 11, 1977 U.S. Pat. No. 4,128,653, issued Dec. 5, 1978, which is a division of application Ser. No. 657,793, filed Feb. 13, 1976, now U.S. Pat. No. 4,052,511, issued Oct. 4, 1977.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3337548 |
Kalopissis et al. |
Aug 1967 |
|
4046889 |
Ondetti et al. |
Sep 1977 |
|
Divisions (1)
|
Number |
Date |
Country |
Parent |
657793 |
Feb 1976 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
768003 |
Feb 1977 |
|