IGF::OT::IGF STAGE VACCINE DEVELOPMENT

Information

  • Research Project
  • 9362986
  • ApplicationId
    9362986
  • Core Project Number
    N01AI000000
  • Full Project Number
    272201600020C-0-0-1
  • Serial Number
  • FOA Number
  • Sub Project Id
  • Project Start Date
    8/1/2016 - 8 years ago
  • Project End Date
    7/31/2017 - 7 years ago
  • Program Officer Name
  • Budget Start Date
    -
  • Budget End Date
    -
  • Fiscal Year
    2016
  • Support Year
  • Suffix
  • Award Notice Date
    -
Organizations

IGF::OT::IGF STAGE VACCINE DEVELOPMENT

The Division of Acquired Immune Deficiency Syndrome (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), is committed to the development of efficacious preventive vaccines against HIV-1 for worldwide use to end the AIDS epidemic. A wide assortment of candidate HIV-1 vaccines have reached Phase I clinical trials but only three vaccine regimens have advanced to efficacy testing. One of these 3 trials, designated RV144, has shown modest efficacy in humans and this result coupled with promising results from nonhuman primate (NHP) studies has now stimulated the field to continue to test more advanced vaccine candidates in humans. Thus, the discovery and development, of preventive HIV/AIDS vaccines may be within reach. To augment the development portion of the process for identifying and ultimately testing an improved HIV vaccine, NIAID will be using a staged development approach to allow the rapid advancement of promising HIV vaccine platforms to CGMP manufacturing for subsequent clinical testing. This project is for the development and manufacture of HIV vaccine candidates that have demonstrated success in NHP challenge studies, equivalent preclinical animal models or early human clinical trials, and have demonstrated manufacturing feasibility.

IC Name
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
  • Activity
    N01
  • Administering IC
    AI
  • Application Type
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    199442
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    855
  • Ed Inst. Type
  • Funding ICs
    NIAID:199442\
  • Funding Mechanism
    Non SBIR/STTR Contracts
  • Study Section
  • Study Section Name
  • Organization Name
    GEOVAX, INC.
  • Organization Department
  • Organization DUNS
    148374205
  • Organization City
    SMYRNA
  • Organization State
    GA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    300807648
  • Organization District
    UNITED STATES