Claims
- 1. Imidazo[1,2-a]quinolines of the general formula (I) ##STR8## in which X is selected from hydrogen, halogen, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, (C.sub.1-4)alkylthio, methylsulphonyl, amino,
- (C.sub.1-4)alkylamino, di-(C.sub.1-4)alkylamino, nitro or trifluoromethyl,
- Y is selected from hydrogen, halogen or methyl in position 6, 7 or 8,
- R.sub.1 and R.sub.2, which may be the same or different, are selected from hydrogen, or (C.sub.1-6)alkyl, or
- R.sub.1 and R.sub.2 together form a group selected from tetramethylene, pentamethylene, 3-methyl-3-azapentamethylene, 3-ethoxycarbonyl-3-azapentamethylene and 3-oxapentamethylene, and
- A and B are both selected from hydrogen or together form a carbon-carbon bond, and their pharmacologically acceptable acid addition salts.
- 2. A compound according to claim 1, in the formula (I) of which X is chlorine, methyl or methylthio, Y is hydrogen, and R.sub.1 and R.sub.2 each are hydrogen or methyl.
- 3. An anxiolytic pharmaceutical composition which comprises an anxiolytically effective amount of a compound as claimed in claim 1 in association with a pharmaceutically acceptable excipient.
- 4. A sleep-inducing or hypnotic pharmaceutical composition which comprises a sleep-inducing or hypnotic effective amount of a compound as claimed in claim 1 in association with a pharmaceutically acceptable excipient.
- 5. An anti-ulcer pharmaceutical composition which comprises an anti-ulceratively effective amount of a compound as claimed in claim 1 in association with a pharmaceutically acceptable excipient.
- 6. An anticonvulsant pharmaceutical composition which comprises an anticonvulsant effective amount of a compound as claimed in claim 1 in association with a pharmaceutically acceptable excipient.
Parent Case Info
This application is a continuation-in-part of U.S. Ser. No. 763,009 filed Aug. 6, 1985, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4387098 |
Barnes et al. |
Jun 1983 |
|
Non-Patent Literature Citations (1)
Entry |
Goodman et al., The Pharmacological Basis of Therapeutics, 6 Ed., p. 28. |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
763009 |
Aug 1985 |
|