The present invention relates to systems and methods for delivering implant devices to a target site or location within the body of a patient.
Delivery of implantable therapeutic devices by less invasive means has been demonstrated to be desirable in numerous clinical situations. For example, vascular embolization has been used to control vascular bleeding, to occlude the blood supply to tumors, to occlude fallopian tubes, and to occlude vascular aneurysms, particularly intracranial aneurysms. In recent years, vascular embolization for the treatment of aneurysms has received much attention. Implants used to treat aneurysms are often convoluted or coiled lengths of wound wire and are referred to as “microcoils.” Microcoils work by filling an aneurysm causing the blood flow through the aneurysm to slow or stop, thereby inducing thrombosis within the aneurysm.
Vascular aneurysms can have extremely thin walls and puncturing an aneurysm wall results in a stroke. Because the walls are so delicate, microcoils are extremely flexible and have very little structural integrity. These microcoils are connected to a pusher system to enable delivery to the treatment site. Ideally, the microcoils and pusher would be sufficiently flexible in order to navigate the vasculature and enable placement within the aneurysm region. However, with traditional designs, there can be significant stiffness, particularly at the pusher-implant connection junction at the proximal end of the microcoil implant.
This rigidity of the proximal end of the coil can be partially attributed to the connection the coil has with the pusher, which is typically attached to the implant and is used to drive the pusher out of a delivery catheter. Often, the proximal end of the coil includes a rigid cylindrical marker band that is held against the distal end of the pusher, adding rigidity to the coil. Additionally, a heater element contained within the distal end of the pusher prevents bending of the distal tip of the pusher, resulting in a rigid implant-pusher junction that increases delivery difficulty. The combination of the heater coil and the marker band thus results in a rigid length at the junction of the implant and the device.
Though several coils and delivery systems have been developed, none have specifically addressed the rigidity at the junction of the implant and the pusher that is due to the sizes and shapes of the implant marker band and/or the length of the heater. Examples of these coils and detachment systems for implant devices are described in the prior art including U.S. Pat. No. 5,895,385 to Guglielmi et al. and U.S. Pat. No. 5,108,407 to Geremia et al., the contents of which are hereby incorporated by reference. Examples of systems using a heater to detach an implant device are disclosed in U.S. Pat. No. 9,867,622 to Bowman, U.S. Pat. No. 6,500,149 to Gandhi et al. and U.S. Pat. No. 4,346,712 to Handa et al., the contents of which are hereby incorporated by reference, describe the use of a heater to detach and deploy the implant device. Additionally, U.S. Pat. No. 8,182,506 to Fitz et al., U.S. Patent Pub. No. 2010/0268204 to Teiu et al., and U.S. Patent Pub. No. 2011/0301686 to Bowman et al., also pertain to thermal detachment systems and are hereby incorporated by reference in their entireties.
It would thus be desirable to develop a coil delivery system that maintains flexibility at the junction of the coil and the pusher. Such a device would promote ease of coil and device positioning during delivery as well as the prevention of coil migration out of the aneurysm after release.
The present invention pertains to a heater and a marker band designed for use with an implant delivery and detachment system used to position and deploy implantable devices such as coils, stents, filters, and the like within a body cavity including, but not limited to, blood vessels, fallopian tubes, malformations such as fistula and aneurysms, heart defects (e.g. left atrial appendages and sepal openings), and other luminal organs.
The heater designs of the present invention include complex shapes and a double-element design made possible through modern manufacturing techniques. The double-element design shortens the length of the heater necessary to achieve the temperatures needed for coil detachment. Heater elements are typically rigid. If a heater element were to flex, it is likely that adjacent windings would make contact with each other and create a short for the current to bypass the windings. Because heater elements are typically rigid, a shorter heater results in a more flexible pusher tip.
In at least one embodiment the heater is created via 3d printing techniques. Typical heaters utilize coils are formed by winding a single length of wire into a coil. The wire has a resistive quality that generates heat as current passes through the windings. Longer coils offer more resistance and thus generate more heat. As such, the coil must be sufficiently long in order to generate enough heat to sever or melt a connecting member (e.g. a tether) to detach the embolic coil. Using 3d printing techniques, vapor deposition, or additive layer concepts, it would be possible to create a multi-layered heating element that incorporates complex geometries to generate more heat for a given length than a traditional heater coil.
In at least one embodiment, the heater utilizes a plurality of connected planes each including an outer incomplete ring and an inner incomplete ring in the form of a C. The complex shape results in a much longer path for current to travel for a given overall heater length than a traditional coil of a similar length would provide. Thus, much more heat is generated. In some embodiments, a protective shell and dielectric material such as polyimide, parylene, and ceramic can be added to the heater to provide insulation between layers.
One aspect provides an implant delivery system that includes a pusher and a heater capsule at a distal end of the pusher. The heater capsule has an outer capsule and a heater element inside the outer capsule. The heater element defines a plurality of planes, each plane including an inner ring and an outer ring. One of the inner ring and the outer ring of each plane is connected to an inner ring or an outer ring, respectively, of an adjacent plane. The heater element also has an electrical connection to the outer capsule. A first lead wire connects the heater element to a power source and a second lead wire connects the outer capsule to the power source.
The marker band is shaped to allow the coil to pivot around the distal end of the pusher prior to release. This configuration significantly increases the flexibility of the interface between the coil and the delivery system.
These and other aspects, features and advantages of which embodiments of the invention are capable of will be apparent and elucidated from the following description of embodiments of the present invention, reference being made to the accompanying drawings, in which:
Specific embodiments of the invention will now be described with reference to the accompanying drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. The terminology used in the detailed description of the embodiments illustrated in the accompanying drawings is not intended to be limiting of the invention. In the drawings, like numbers refer to like elements.
This heater element embodiment 10 is of a unitary construction and includes a complex, double element. The double element is a continuous length of material that begins at a distal tab 12 and extends in a first plane 14A around an outer ring 16A of the C-shape, or incomplete circle shape, and then turns inwardly to form an inner ring 18A of the C-shape, in the same first plane 14A. The inner ring extends back to the other end of the C, adjacent the tab 12, at which point the element plane connects to an adjacent, second plane 14B and forms another C-shaped layer, beginning this time with the inner ring 18B and ending with an outer ring 16B. This pattern is repeated until a number of planes (six planes 14A-F are shown in the example of
Through additive manufacturing, alternative complex element shapes could be developed that would not be possible with more conventional manufacturing methods. One skilled in the art will realize the present invention should not be construed to be limited to the C-shaped embodiment of
According to one embodiment, the heater element 10 defines an internal passage 20. The internal passage 20 may be sized to solely contain a tether connecting the implant to the pusher 60. According to another embodiment, the internal passage 20 may be large enough to contain the tether and other components, such as a support mandrel or electrical wires.
A proximal end 22 of the heater element 10 includes a passage 24 defined between tabs 26. The passage 24 is sized to receive a lead wire 68 (
In the embodiment of
In one embodiment, opening 38 is used to receive a negative terminal lead wire 66 (
Opening 40 may be used to attach a stretch-resistant wire 64 (
The cap 36 of the capsule 32 defines a lumen 50, through which a tether is routed for connecting the implant to the pusher 60. The lumen 50 may have a diameter that matches or approximates the diameter of the internal passage 20 of the heater element 10. The tether passes through the heater 10 and is severed, melted or broken by the heater 10 when the heater 10 is activated in order to release the implant. The cap has a diameter that is greater than the capsule body 34 such that an overhang 52 is created. The overhang 52 acts as a stop against the pusher 60 when the capsule 32 is inserted into the distal end 62 of the pusher coil 61. A protrusion 54 extends proximally from the proximal side of the cap 36 and acts against a distal terminus 62 of the pusher coil 61.
In the example of
Many delivery pushers used to deliver an embolic coil utilize a marker band just proximal of the embolic coil. The embodiments of
The example of
Although the invention has been described in terms of particular embodiments and applications, one of ordinary skill in the art, in light of this teaching, can generate additional embodiments and modifications without departing from the spirit of or exceeding the scope of the claimed invention. Accordingly, it is to be understood that the drawings and descriptions herein are proffered by way of example to facilitate comprehension of the invention and should not be construed to limit the scope thereof.
This application claims priority to U.S. Provisional Application Ser. No. 62/775,816 filed Dec. 5, 2018 entitled Implant Delivery System, which is hereby incorporated herein by reference in its entirety.
Number | Name | Date | Kind |
---|---|---|---|
3324280 | Cheney et al. | Jun 1967 | A |
4346712 | Handa et al. | Aug 1982 | A |
4364392 | Strother et al. | Dec 1982 | A |
4402319 | Handa et al. | Sep 1983 | A |
4487754 | Reed | Dec 1984 | A |
4512338 | Balko et al. | Apr 1985 | A |
4545367 | Tucci | Oct 1985 | A |
4551132 | Pasztor et al. | Nov 1985 | A |
4638803 | Rand | Jan 1987 | A |
RE32348 | Pevsner | Feb 1987 | E |
4735201 | O'Reilly | Apr 1988 | A |
4795741 | Leshchiner et al. | Jan 1989 | A |
4819637 | Dormandy, Jr. et al. | Apr 1989 | A |
4885217 | Hoge | Dec 1989 | A |
4944746 | Iwata et al. | Jul 1990 | A |
4994069 | Ritchart et al. | Feb 1991 | A |
5001009 | Whitbourne | Mar 1991 | A |
5059213 | Chesterfield et al. | Oct 1991 | A |
5108407 | Geremia et al. | Apr 1992 | A |
5122136 | Guglielmi et al. | Jun 1992 | A |
5133731 | Butler et al. | Jul 1992 | A |
5147317 | Shank et al. | Sep 1992 | A |
5147370 | McNamara et al. | Sep 1992 | A |
5163952 | Froix | Nov 1992 | A |
5167624 | Butler et al. | Dec 1992 | A |
5176140 | Kami et al. | Jan 1993 | A |
5217484 | Marks | Jun 1993 | A |
5226911 | Chee et al. | Jul 1993 | A |
5242452 | Inoue | Sep 1993 | A |
5250071 | Palermo | Oct 1993 | A |
5256146 | Ensminger et al. | Oct 1993 | A |
5258042 | Mehta | Nov 1993 | A |
5261916 | Engelson | Nov 1993 | A |
5269030 | Pahno et al. | Dec 1993 | A |
5290305 | Inoue | Mar 1994 | A |
5304194 | Chee et al. | Apr 1994 | A |
5311027 | Schuetz | May 1994 | A |
5312415 | Palermo | May 1994 | A |
5331027 | Whitbourne | Jul 1994 | A |
5334201 | Cowan | Aug 1994 | A |
5334210 | Gianturco | Aug 1994 | A |
5350397 | Palermo et al. | Sep 1994 | A |
5354295 | Guglielmi et al. | Oct 1994 | A |
5382259 | Phelps et al. | Jan 1995 | A |
5382260 | Dormandy, Jr. et al. | Jan 1995 | A |
5383853 | Jung et al. | Jan 1995 | A |
5383887 | Nadal | Jan 1995 | A |
5423777 | Tajiri et al. | Jun 1995 | A |
5423829 | Pham et al. | Jun 1995 | A |
5423849 | Engelson et al. | Jun 1995 | A |
5433708 | Nichols et al. | Jul 1995 | A |
5443454 | Tanabe et al. | Aug 1995 | A |
5443478 | Purdy | Aug 1995 | A |
5443495 | Buscemi et al. | Aug 1995 | A |
5469867 | Schmitt | Nov 1995 | A |
5470338 | Whitfield et al. | Nov 1995 | A |
5476472 | Dormandy | Dec 1995 | A |
5498227 | Mawad | Mar 1996 | A |
5498250 | Prather | Mar 1996 | A |
5522836 | Palermo | Jun 1996 | A |
5525334 | Ito et al. | Jun 1996 | A |
5529653 | Glastra | Jun 1996 | A |
5536274 | Neuss | Jul 1996 | A |
5540680 | Guglielmi et al. | Jul 1996 | A |
5569245 | Guglielmi et al. | Oct 1996 | A |
5578074 | Mirigian | Nov 1996 | A |
5580568 | Greff et al. | Dec 1996 | A |
5582619 | Ken | Dec 1996 | A |
5593412 | Martinez et al. | Jan 1997 | A |
5601600 | Ton | Feb 1997 | A |
5609608 | Benett et al. | Mar 1997 | A |
5612050 | Rowe et al. | Mar 1997 | A |
5614204 | Cochrum | Mar 1997 | A |
5624449 | Pham et al. | Apr 1997 | A |
5624461 | Mariant | Apr 1997 | A |
5624685 | Takahashi et al. | Apr 1997 | A |
5634936 | Linden et al. | Jun 1997 | A |
5639277 | Mariant et al. | Jun 1997 | A |
5645558 | Horton | Jul 1997 | A |
5658308 | Snyder | Aug 1997 | A |
5667767 | Greff et al. | Sep 1997 | A |
5669905 | Scheldrup et al. | Sep 1997 | A |
5669931 | Kupiecki et al. | Sep 1997 | A |
5676671 | Inoue | Oct 1997 | A |
5690667 | Gia | Nov 1997 | A |
5690671 | McGurk et al. | Nov 1997 | A |
5700258 | Mirigian et al. | Dec 1997 | A |
5702361 | Evans et al. | Dec 1997 | A |
5718711 | Berenstein et al. | Feb 1998 | A |
5722989 | Fitch et al. | Mar 1998 | A |
5725546 | Samson | Mar 1998 | A |
5725568 | Hastings | Mar 1998 | A |
5733329 | Wallace et al. | Mar 1998 | A |
5743905 | Eder et al. | Apr 1998 | A |
5749891 | Ken et al. | May 1998 | A |
5749894 | Engelson | May 1998 | A |
5749921 | Lenker et al. | May 1998 | A |
5750585 | Park et al. | May 1998 | A |
5759161 | Ogawa et al. | Jun 1998 | A |
5766204 | Porter et al. | Jun 1998 | A |
5766219 | Horton | Jun 1998 | A |
5792154 | Doan et al. | Aug 1998 | A |
5800454 | Jacobsen et al. | Sep 1998 | A |
5800455 | Palermo et al. | Sep 1998 | A |
5814062 | Sepetka et al. | Sep 1998 | A |
5823198 | Jones et al. | Oct 1998 | A |
5830178 | Jones et al. | Nov 1998 | A |
5830230 | Berryman et al. | Nov 1998 | A |
5846210 | Ogawa et al. | Dec 1998 | A |
5846247 | Unsworth et al. | Dec 1998 | A |
5851206 | Guglielmi et al. | Dec 1998 | A |
5851508 | Greff et al. | Dec 1998 | A |
5853418 | Ken et al. | Dec 1998 | A |
5855578 | Guglielmi et al. | Jan 1999 | A |
5873835 | Hastings et al. | Feb 1999 | A |
5879499 | Corvi | Mar 1999 | A |
5891058 | Taki et al. | Apr 1999 | A |
5891130 | Palermo et al. | Apr 1999 | A |
5895385 | Guglielmi et al. | Apr 1999 | A |
5902254 | Magram | May 1999 | A |
5911737 | Lee et al. | Jun 1999 | A |
5925037 | Guglielmi et al. | Jul 1999 | A |
5925059 | Palermo et al. | Jul 1999 | A |
5925061 | Ogi et al. | Jul 1999 | A |
5928226 | Guglielmi et al. | Jul 1999 | A |
5941888 | Wallace et al. | Aug 1999 | A |
5944714 | Guglielmi et al. | Aug 1999 | A |
5944733 | Engelson | Aug 1999 | A |
5947962 | Guglielmi et al. | Sep 1999 | A |
5947963 | Guglielmi | Sep 1999 | A |
5964771 | Beyar et al. | Oct 1999 | A |
5964797 | Ho | Oct 1999 | A |
5976126 | Guglielmi | Nov 1999 | A |
5976131 | Guglielmi et al. | Nov 1999 | A |
5984629 | Brodersen et al. | Nov 1999 | A |
5984929 | Bashiri et al. | Nov 1999 | A |
5984944 | Forber | Nov 1999 | A |
5989242 | Saadat et al. | Nov 1999 | A |
6010498 | Guglielmi | Jan 2000 | A |
6013084 | Ken et al. | Jan 2000 | A |
6015424 | Rosenbluth et al. | Jan 2000 | A |
6033423 | Ken et al. | Mar 2000 | A |
6048338 | Larson et al. | Apr 2000 | A |
6053873 | Govari et al. | Apr 2000 | A |
6056759 | Fiedler | May 2000 | A |
6059815 | Lee et al. | May 2000 | A |
6063070 | Eder | May 2000 | A |
6063100 | Diaz et al. | May 2000 | A |
6066133 | Guglielmi et al. | May 2000 | A |
6068644 | Lulo et al. | May 2000 | A |
6077291 | Das | Jun 2000 | A |
6083220 | Guglielmi et al. | Jul 2000 | A |
6086599 | Lee et al. | Jul 2000 | A |
6091980 | Squire et al. | Jul 2000 | A |
6102932 | Kurz | Aug 2000 | A |
6102933 | Lee et al. | Aug 2000 | A |
6117142 | Goodson et al. | Sep 2000 | A |
6159206 | Ogawa | Dec 2000 | A |
6165178 | Bashiri et al. | Dec 2000 | A |
6183491 | Lulo | Feb 2001 | B1 |
6183504 | Inoue | Feb 2001 | B1 |
6193728 | Ken et al. | Feb 2001 | B1 |
6221066 | Ferrera et al. | Apr 2001 | B1 |
6224609 | Ressemann et al. | May 2001 | B1 |
6224610 | Ferrera | May 2001 | B1 |
6238403 | Greene, Jr. et al. | May 2001 | B1 |
6238415 | Sepetka et al. | May 2001 | B1 |
6270520 | Inoue | Aug 2001 | B1 |
6277126 | Barry et al. | Aug 2001 | B1 |
6287318 | Villar et al. | Sep 2001 | B1 |
6293960 | Ken | Sep 2001 | B1 |
6296622 | Kurz et al. | Oct 2001 | B1 |
6299619 | Greene, Jr. et al. | Oct 2001 | B1 |
6312407 | Zadno-Azizi et al. | Nov 2001 | B1 |
6319267 | Kurz | Nov 2001 | B1 |
6338657 | Harper et al. | Jan 2002 | B1 |
6361547 | Hieshima | Mar 2002 | B1 |
6371979 | Beyar et al. | Apr 2002 | B1 |
6375668 | Gifford et al. | Apr 2002 | B1 |
6375669 | Rosenbluth et al. | Apr 2002 | B1 |
6383204 | Ferrera et al. | May 2002 | B1 |
6397850 | Scheldrup et al. | Jun 2002 | B1 |
6425893 | Guglielmi | Jul 2002 | B1 |
6428557 | Hilaire | Aug 2002 | B1 |
6440098 | Luscher | Aug 2002 | B1 |
6447522 | Gambale et al. | Sep 2002 | B2 |
6454780 | Wallace | Sep 2002 | B1 |
6478773 | Ghandi et al. | Nov 2002 | B1 |
6494884 | Gifford, III et al. | Dec 2002 | B2 |
6500149 | Gandhi et al. | Dec 2002 | B2 |
6514264 | Naglreiter | Feb 2003 | B1 |
6514282 | Inoue | Feb 2003 | B1 |
6526979 | Nikolchev et al. | Mar 2003 | B1 |
6537284 | Inoue | Mar 2003 | B1 |
6544225 | Lulo et al. | Apr 2003 | B1 |
6551305 | Ferrera et al. | Apr 2003 | B2 |
6551340 | Konya et al. | Apr 2003 | B1 |
6554849 | Jones et al. | Apr 2003 | B1 |
6585718 | Hayzelden et al. | Jul 2003 | B2 |
6602261 | Greene, Jr. et al. | Aug 2003 | B2 |
6602269 | Wallace et al. | Aug 2003 | B2 |
6607538 | Ferrera et al. | Aug 2003 | B1 |
6610046 | Usami et al. | Aug 2003 | B1 |
6634361 | Nikolchev et al. | Oct 2003 | B1 |
6645240 | Yee | Nov 2003 | B2 |
6656173 | Palermo | Dec 2003 | B1 |
6684884 | Nikolchev et al. | Feb 2004 | B2 |
6689141 | Ferrera et al. | Feb 2004 | B2 |
6705323 | Nikolchev et al. | Mar 2004 | B1 |
6716238 | Elliott | Apr 2004 | B2 |
6740073 | Saville | May 2004 | B1 |
6743236 | Barry et al. | Jun 2004 | B2 |
6743251 | Eder | Jun 2004 | B1 |
6807446 | Fenn et al. | Oct 2004 | B2 |
6849081 | Sepetka et al. | Feb 2005 | B2 |
6849087 | Chuter | Feb 2005 | B1 |
6855125 | Shanley | Feb 2005 | B2 |
6895276 | Kast et al. | May 2005 | B2 |
6905503 | Gifford, III et al. | Jun 2005 | B2 |
6953465 | Dieck et al. | Oct 2005 | B2 |
6953473 | Porter | Oct 2005 | B2 |
6958068 | Hieshima | Oct 2005 | B2 |
6964671 | Cheng et al. | Nov 2005 | B2 |
6966892 | Ghandi et al. | Nov 2005 | B2 |
6989020 | Jones et al. | Jan 2006 | B2 |
7001422 | Escamilla et al. | Feb 2006 | B2 |
7014645 | Greene, Jr. et al. | Mar 2006 | B2 |
7048719 | Monetti | May 2006 | B1 |
7063671 | Couvillon, Jr. | Jun 2006 | B2 |
7063707 | Bose et al. | Jun 2006 | B2 |
7066904 | Rosenthal et al. | Jun 2006 | B2 |
7070609 | West | Jul 2006 | B2 |
7108708 | Cheng et al. | Sep 2006 | B2 |
7137990 | Herbert et al. | Nov 2006 | B2 |
7147618 | Kurz | Dec 2006 | B2 |
7166122 | Aganon et al. | Jan 2007 | B2 |
7179276 | Barry et al. | Feb 2007 | B2 |
7182774 | Barry et al. | Feb 2007 | B2 |
7198613 | Gandhi et al. | Apr 2007 | B2 |
7201768 | Diaz et al. | Apr 2007 | B2 |
7208003 | Davis et al. | Apr 2007 | B2 |
7238194 | Monstdt et al. | Jul 2007 | B2 |
7255707 | Ramzipoor et al. | Aug 2007 | B2 |
7264628 | Jones et al. | Sep 2007 | B2 |
7270674 | Jones et al. | Sep 2007 | B2 |
7309345 | Wallace | Dec 2007 | B2 |
7323000 | Monstdt et al. | Jan 2008 | B2 |
7326225 | Ferrera et al. | Feb 2008 | B2 |
7344558 | Lorenzo et al. | Mar 2008 | B2 |
7351254 | Magers | Apr 2008 | B2 |
7357809 | Jones et al. | Apr 2008 | B2 |
7367987 | Balgobin et al. | May 2008 | B2 |
7371251 | Mitelberg et al. | May 2008 | B2 |
7371252 | Balgobin et al. | May 2008 | B2 |
7377932 | Mitelberg et al. | May 2008 | B2 |
7513878 | Hamilton | Apr 2009 | B2 |
7553321 | Litzenberg et al. | Jun 2009 | B2 |
7575582 | Gandhi et al. | Aug 2009 | B2 |
7578826 | Gandhi et al. | Aug 2009 | B2 |
7582101 | Jones et al. | Sep 2009 | B2 |
7585317 | Davidson et al. | Sep 2009 | B2 |
7591833 | Jones et al. | Sep 2009 | B2 |
7608089 | Wallace et al. | Oct 2009 | B2 |
RE41029 | Guglielmi et al. | Dec 2009 | E |
7628797 | Tieu et al. | Dec 2009 | B2 |
7651513 | Teoh et al. | Jan 2010 | B2 |
7691118 | Gorospe | Apr 2010 | B2 |
7691121 | Rosenbluth et al. | Apr 2010 | B2 |
7691124 | Balgobin | Apr 2010 | B2 |
7708754 | Balgobin et al. | May 2010 | B2 |
7708755 | Davis, III et al. | May 2010 | B2 |
7740637 | Gandhi et al. | Jun 2010 | B2 |
7771451 | Ramzipoor | Aug 2010 | B2 |
7776054 | Gandhi et al. | Aug 2010 | B2 |
7780645 | Jones | Aug 2010 | B2 |
7780680 | Gandhi et al. | Aug 2010 | B2 |
7789891 | Wallace | Sep 2010 | B2 |
7811305 | Balgobin et al. | Oct 2010 | B2 |
7918872 | Mitelberg et al. | Apr 2011 | B2 |
7924636 | Morimoto et al. | Apr 2011 | B2 |
7942894 | West | May 2011 | B2 |
7947060 | Mazzocchi et al. | May 2011 | B2 |
RE42662 | Guglielmi et al. | Aug 2011 | E |
RE42756 | Guglielmi et al. | Sep 2011 | E |
8034073 | Davis, III et al. | Oct 2011 | B2 |
8034094 | Aoba et al. | Oct 2011 | B2 |
8114145 | Hartley et al. | Feb 2012 | B2 |
8142455 | Thompson et al. | Mar 2012 | B2 |
8182506 | Fitz et al. | May 2012 | B2 |
8192480 | Tieu et al. | Jun 2012 | B2 |
8206413 | Jones et al. | Jun 2012 | B2 |
8267955 | Patterson et al. | Sep 2012 | B2 |
8460332 | Tieu et al. | Jun 2013 | B2 |
8652163 | Padilla et al. | Feb 2014 | B2 |
8728142 | Gandhi et al. | May 2014 | B2 |
8795316 | Balgobin et al. | Aug 2014 | B2 |
8864790 | Strauss et al. | Oct 2014 | B2 |
8932317 | Marks et al. | Jan 2015 | B2 |
8956381 | Que et al. | Feb 2015 | B2 |
8998926 | Pomeranz | Apr 2015 | B2 |
9242070 | Tieu | Jan 2016 | B2 |
9265504 | Kellett | Feb 2016 | B2 |
9301862 | Jordan et al. | Apr 2016 | B2 |
9307996 | Johnson et al. | Apr 2016 | B2 |
9414819 | Fitz et al. | Aug 2016 | B2 |
9486223 | Que et al. | Nov 2016 | B2 |
9504475 | Chen et al. | Nov 2016 | B2 |
9510962 | Aoba et al. | Dec 2016 | B2 |
9717500 | Tieu et al. | Aug 2017 | B2 |
9775620 | Teoh et al. | Oct 2017 | B2 |
9788840 | Marks et al. | Oct 2017 | B2 |
9814465 | Win et al. | Nov 2017 | B2 |
9867622 | Bowman | Jan 2018 | B2 |
9889028 | Rasmussen et al. | Feb 2018 | B2 |
10299755 | Tieu | May 2019 | B2 |
10413302 | Fitz et al. | Sep 2019 | B2 |
10478192 | Teoh et al. | Nov 2019 | B2 |
10524799 | O'Connor et al. | Jan 2020 | B2 |
10813779 | Fleming, III et al. | Oct 2020 | B2 |
10932926 | Bar et al. | Mar 2021 | B2 |
20010029352 | Gandhi et al. | Oct 2001 | A1 |
20010041898 | Barry et al. | Nov 2001 | A1 |
20010044633 | Klint | Nov 2001 | A1 |
20010049521 | Gia et al. | Dec 2001 | A1 |
20020029035 | Lee et al. | Mar 2002 | A1 |
20020046756 | Laizzo et al. | Apr 2002 | A1 |
20020091380 | Wheelock et al. | Jul 2002 | A1 |
20020099408 | Marks et al. | Jul 2002 | A1 |
20020107534 | Schaefer et al. | Aug 2002 | A1 |
20020123755 | Lowe et al. | Sep 2002 | A1 |
20020173837 | Lauterjung | Nov 2002 | A1 |
20020188341 | Elliott | Dec 2002 | A1 |
20030023262 | Welch | Jan 2003 | A1 |
20030045859 | Dominguez | Mar 2003 | A1 |
20030045901 | Opolski | Mar 2003 | A1 |
20030069539 | Gandhi et al. | Apr 2003 | A1 |
20030125790 | Fastovsky et al. | Jul 2003 | A1 |
20040002731 | Aganon et al. | Jan 2004 | A1 |
20040002733 | Teoh | Jan 2004 | A1 |
20040034363 | Wilson et al. | Feb 2004 | A1 |
20040044385 | Fenn et al. | Mar 2004 | A1 |
20040111029 | Bates et al. | Jun 2004 | A1 |
20040181177 | Lee et al. | Sep 2004 | A1 |
20040204701 | Cox et al. | Oct 2004 | A1 |
20040220563 | Eder | Nov 2004 | A1 |
20050021023 | Guglielmi et al. | Jan 2005 | A1 |
20050043755 | Wilson et al. | Feb 2005 | A1 |
20050113864 | Gandhi et al. | May 2005 | A1 |
20050118865 | Henningsen | Jun 2005 | A1 |
20050131523 | Bashiri et al. | Jun 2005 | A1 |
20050149108 | Cox | Jul 2005 | A1 |
20050154417 | Sepetka et al. | Jul 2005 | A1 |
20050154440 | Limon | Jul 2005 | A1 |
20050171572 | Martinez | Aug 2005 | A1 |
20050222580 | Gifford, III et al. | Oct 2005 | A1 |
20050273020 | Whittaker et al. | Dec 2005 | A1 |
20050283182 | Pierce et al. | Dec 2005 | A1 |
20060025801 | Lulo et al. | Feb 2006 | A1 |
20060025802 | Sowers | Feb 2006 | A1 |
20060025803 | Mitelberg et al. | Feb 2006 | A1 |
20060036280 | French et al. | Feb 2006 | A1 |
20060052815 | Fitz et al. | Mar 2006 | A1 |
20060079923 | Chhabra et al. | Apr 2006 | A1 |
20060116584 | Sudol et al. | Jun 2006 | A1 |
20060116708 | Ogawa et al. | Jun 2006 | A1 |
20060116714 | Sepetka et al. | Jun 2006 | A1 |
20060135986 | Wallace et al. | Jun 2006 | A1 |
20060173488 | Takeuchi et al. | Aug 2006 | A1 |
20060184092 | Atanasoska et al. | Aug 2006 | A1 |
20060200192 | Fitz et al. | Sep 2006 | A1 |
20060241682 | Kurz | Oct 2006 | A1 |
20060241684 | Wilson et al. | Oct 2006 | A1 |
20060241685 | Wilson et al. | Oct 2006 | A1 |
20060253023 | Lewis et al. | Nov 2006 | A1 |
20060253149 | Gandhi et al. | Nov 2006 | A1 |
20060271097 | Ramzipoor et al. | Nov 2006 | A1 |
20060271098 | Peacock, III | Nov 2006 | A1 |
20060271099 | Marks et al. | Nov 2006 | A1 |
20060276825 | Mitelberg et al. | Dec 2006 | A1 |
20060276826 | Mitelberg et al. | Dec 2006 | A1 |
20060276829 | Balgobin et al. | Dec 2006 | A1 |
20060276830 | Balgobin et al. | Dec 2006 | A1 |
20060276834 | Balgobin et al. | Dec 2006 | A1 |
20070010849 | Balgobin et al. | Jan 2007 | A1 |
20070055302 | Henry et al. | Mar 2007 | A1 |
20070073334 | Ramzipoor | Mar 2007 | A1 |
20070100419 | Licata et al. | May 2007 | A1 |
20070104752 | Lee et al. | May 2007 | A1 |
20070123927 | Farnan | May 2007 | A1 |
20070123928 | Farnan | May 2007 | A1 |
20070167911 | Gandhi et al. | Jul 2007 | A1 |
20070185443 | Euteneuer et al. | Aug 2007 | A1 |
20070185457 | Euteneuer et al. | Aug 2007 | A1 |
20070191879 | Gandhi et al. | Aug 2007 | A1 |
20070203452 | Mehta | Aug 2007 | A1 |
20070208276 | Kornkven Volk et al. | Sep 2007 | A1 |
20070221230 | Thompson et al. | Sep 2007 | A1 |
20070239141 | Hartley et al. | Oct 2007 | A1 |
20070239193 | Simon et al. | Oct 2007 | A1 |
20070239196 | Pomeranz | Oct 2007 | A1 |
20070249924 | Takata et al. | Oct 2007 | A1 |
20070265637 | Andreas et al. | Nov 2007 | A1 |
20070270903 | Davis, III et al. | Nov 2007 | A1 |
20070299461 | Elliott | Dec 2007 | A1 |
20080045997 | Balgobin et al. | Feb 2008 | A1 |
20080097462 | Mitelberg et al. | Apr 2008 | A1 |
20080103585 | Monstadt et al. | May 2008 | A1 |
20080119887 | Que et al. | May 2008 | A1 |
20080119891 | Miles et al. | May 2008 | A1 |
20080125855 | Henkes et al. | May 2008 | A1 |
20080133028 | Wilson et al. | Jun 2008 | A1 |
20080140111 | Wilson et al. | Jun 2008 | A1 |
20080140178 | Rasmussen et al. | Jun 2008 | A1 |
20080147201 | Wilson et al. | Jun 2008 | A1 |
20080172119 | Yamasaki et al. | Jul 2008 | A1 |
20080221554 | O'Connor et al. | Sep 2008 | A1 |
20080221654 | Buiser et al. | Sep 2008 | A1 |
20080228215 | Strauss et al. | Sep 2008 | A1 |
20080243218 | Bottomley et al. | Oct 2008 | A1 |
20080246231 | Sjostedt et al. | Oct 2008 | A1 |
20080275464 | Abrams et al. | Nov 2008 | A1 |
20080283066 | Delgado et al. | Nov 2008 | A1 |
20080287982 | Harreld | Nov 2008 | A1 |
20080306503 | Que et al. | Dec 2008 | A1 |
20090018653 | Bashiri et al. | Jan 2009 | A1 |
20090024154 | Williams et al. | Jan 2009 | A1 |
20090054905 | Levy | Feb 2009 | A1 |
20090062726 | Ford et al. | Mar 2009 | A1 |
20090062812 | Fitz et al. | Mar 2009 | A1 |
20090076540 | Marks et al. | Mar 2009 | A1 |
20090082842 | Glynn | Mar 2009 | A1 |
20090099592 | Buiser et al. | Apr 2009 | A1 |
20090138036 | Nardone et al. | May 2009 | A1 |
20090143786 | Bashiri et al. | Jun 2009 | A1 |
20090163780 | Tieu | Jun 2009 | A1 |
20090163986 | Tieu et al. | Jun 2009 | A1 |
20090177261 | Teoh et al. | Jul 2009 | A1 |
20090254111 | Monstadt et al. | Oct 2009 | A1 |
20090270901 | Kelleher et al. | Oct 2009 | A1 |
20090270903 | Litzenberg et al. | Oct 2009 | A1 |
20090275971 | Kelleher et al. | Nov 2009 | A1 |
20090299275 | Gandhi et al. | Dec 2009 | A1 |
20090318892 | Aboytes et al. | Dec 2009 | A1 |
20100004731 | Gandhi et al. | Jan 2010 | A1 |
20100042133 | Ramzipoor et al. | Feb 2010 | A1 |
20100069838 | Weber et al. | Mar 2010 | A1 |
20100094395 | Kellett | Apr 2010 | A1 |
20100106162 | Jaeger et al. | Apr 2010 | A1 |
20100152650 | Schrodt | Jun 2010 | A1 |
20100152828 | Pakbaz et al. | Jun 2010 | A1 |
20100160944 | Teoh | Jun 2010 | A1 |
20100160953 | Ngo et al. | Jun 2010 | A1 |
20100160983 | Runco et al. | Jun 2010 | A1 |
20100199448 | Vazales et al. | Aug 2010 | A1 |
20100234872 | Guo et al. | Sep 2010 | A1 |
20100249823 | Gandhi et al. | Sep 2010 | A1 |
20100256666 | Chen et al. | Oct 2010 | A1 |
20100268158 | Porter | Oct 2010 | A1 |
20100268201 | Tieu et al. | Oct 2010 | A1 |
20100268204 | Tieu et al. | Oct 2010 | A1 |
20100268251 | Chen et al. | Oct 2010 | A1 |
20100268252 | Chen et al. | Oct 2010 | A1 |
20110046282 | Mizuta et al. | Feb 2011 | A1 |
20110059639 | Dilmaghanian et al. | Mar 2011 | A1 |
20110092997 | Kang | Apr 2011 | A1 |
20110106098 | Williams | May 2011 | A1 |
20110160824 | Ware et al. | Jun 2011 | A1 |
20110301686 | Bowman et al. | Dec 2011 | A1 |
20110313443 | Lorenzo | Dec 2011 | A1 |
20120041470 | Shrivastava | Feb 2012 | A1 |
20120065667 | Javois et al. | Mar 2012 | A1 |
20120116350 | Strauss et al. | May 2012 | A1 |
20120315798 | Poon et al. | Dec 2012 | A1 |
20130012046 | Jullien et al. | Jan 2013 | A1 |
20130085520 | Liang et al. | Apr 2013 | A1 |
20130138136 | Beckham | May 2013 | A1 |
20130245745 | Vong et al. | Sep 2013 | A1 |
20130261656 | Lorenzo | Oct 2013 | A1 |
20130261657 | Lorenzo | Oct 2013 | A1 |
20140058434 | Jones et al. | Feb 2014 | A1 |
20140142611 | Plaza et al. | May 2014 | A1 |
20140206958 | Laramy et al. | Jul 2014 | A1 |
20140236127 | Lee | Aug 2014 | A1 |
20140277092 | Teoh et al. | Sep 2014 | A1 |
20140277093 | Guo et al. | Sep 2014 | A1 |
20140277094 | Chen et al. | Sep 2014 | A1 |
20150057700 | Chen et al. | Feb 2015 | A1 |
20150173772 | Bowman et al. | Jun 2015 | A1 |
20150173773 | Bowman | Jun 2015 | A1 |
20150289879 | Bowman | Oct 2015 | A1 |
20160081693 | Lorenzo | Mar 2016 | A1 |
20160345904 | Bowman | Dec 2016 | A1 |
20170105739 | Dias | Apr 2017 | A1 |
20180078263 | Stoppenhagen | Mar 2018 | A1 |
20180338767 | Dasnurkar et al. | Nov 2018 | A1 |
20190192162 | Lorenzo | Jun 2019 | A1 |
Number | Date | Country |
---|---|---|
2493016 | Feb 2004 | CA |
1 538 997 | Jun 2005 | EP |
1 738 698 | Jan 2007 | EP |
1 884 208 | Feb 2008 | EP |
1 120 088 | Apr 2009 | EP |
1 886 632 | Apr 2011 | EP |
S52141092 | Nov 1977 | JP |
S5643962 | Apr 1981 | JP |
H0247219 | Dec 1988 | JP |
H01238874 | Sep 1989 | JP |
5158069 | Jun 1993 | JP |
H0966109 | Mar 1997 | JP |
H10127647 | May 1998 | JP |
WO 1994006503 | Mar 1994 | WO |
WO 1995027443 | Oct 1995 | WO |
WO 1998040033 | Sep 1998 | WO |
WO 1999006097 | Feb 1999 | WO |
WO 2002055146 | Jul 2002 | WO |
WO 2004008974 | Jan 2004 | WO |
WO 2004010877 | Feb 2004 | WO |
WO 2006126474 | Nov 2006 | WO |
WO 2007070788 | Jun 2007 | WO |
WO 2007070793 | Jun 2007 | WO |
WO 2013149684 | Oct 2013 | WO |
Entry |
---|
Graves, V.B. et al., “Endovascular Occlusion of the Carotid or Vertebral Artery with Temporary Proximal Flow Arrest and Microcoils: Clinical Results,” AJNR Am J Neuroradiol 18:1201-1206, American Society of Neuroradiology, Aug. 1997, 6 pages. |
Rosenthal M.D., D. et al., “Endovascular infrainguinal in situ saphenous vein bypass: A multicenter preliminary report,” J. Vasc Surg Sep. 1992, vol. 3, No. 16, pp. 453-458, 6 pages. |
Rosenthal, D. et al., “Angioscope-assisted endovascular occlusion of venous tributaries: preclinical studies,” Cardiovasc Surg Jun. 1993, vol. 1, No. 3, pp. 225-227, 3 pages. |
Schmutz, F. et al., “Embolization of Cerebral Arteriovenous Malformations with Silk: Histophathologic Changes and Hemorrhagic Complications,” AJNR Am J Neuroradiol 18: 1233-1237, Aug. 1997, 5 pages. |
Viñuela M.D., F. et al., “Guglielmi detachable coil embolization of acute intracranial aneurysm: perioperative anatomical and clinical outcome in 403 patients,” J Neurosurg 86:475-486, Mar. 1997, 8 pages. |
WIPO, European International Search Authority, International Search Report dated Nov. 27, 2000 in International Patent Application No. PCT/US2000/015445, 6 pages. |
WIPO, U.S. International Search Authority, International Search Report mailed Mar. 19, 2009 in International Patent Application No. PCT/US2008/087855, 8 pages. |
WIPO, U.S. International Search Authority, International Search Report mailed May 28, 2002 in International Patent Application No. PCT/US2001/032588, 5 pages. |
WIPO, U.S. International Search Authority, International Search Report and Written Opinion mailed Jul. 9, 2015 in International Patent Application No. PCT/US2015/025594, 10 pages. |
WIPO, U.S. International Search Authority, International Search Report and Written Opinion mailed May 27, 2014 in International Patent Application No. PCT/US2014/019155, 10pages. |
WIPO, U.S. International Search Authority, International Search Report and Written Opinion mailed Jun. 8, 2010 in International Patent Application No. PCT/US2010/031268, 9 pages. |
WIPO, U.S. International Search Authority, International Search Report and Written Opinion mailed Oct. 20, 2008 in International Patent Application No. PCT/US2008/071325, 10 pages. |
Number | Date | Country | |
---|---|---|---|
20200178975 A1 | Jun 2020 | US |
Number | Date | Country | |
---|---|---|---|
62775816 | Dec 2018 | US |