Claims
- 1. A method of manufacturing an implant, comprising the steps of:
- providing a main body member having bio-compatibility;
- dispersedly providing particles formed of material including calcium phosphate at a surface of a proccessed portion of said main body member formed of titanium or titanium alloy such that each of said particles has a part embedded in said processed portion surface and a part protruding from said processed portion surface; and
- forming a titanium oxide layer on said processed portion surface and a hydroxylapatite layer on a surface of each of said particles.
- 2. A method according to claim 1, wherein said step of forming a titanium oxide layer includes performing hydrothermal process to said processed portion surface.
- 3. A method according to claim 2, wherein a solution used in said hydrothermal process is selected from among a group consisting of pseudo-humor, suspension or saturated solution of calcium phosphate, and mixture solution of them.
- 4. A method according to claim 1, wherein said particles are formed of material selected from among a group consisting of sintered substances of hydroxylapatite, .alpha.-tricalcium phosphate, .beta.-tricalcium phosphate, tetra-calcium phosphate, a single substance of amorphous calcium phosphate, monetite, brushite, 45S4 glass, and a mixture of them.
- 5. A method according to claims 1, further comprising the step of performing a secondary sand blasting process to said processed portion surface using secondary blasting particles formed of bioactive material such that each of said secondary blasting particles has a part embedded in said processed portion surface and a part protruding from said processed portion surface.
- 6. A method according to claim 5, wherein said secondary blasting particles have osteo-conduction.
- 7. A method according to claim 6, wherein said secondary blasting particles are formed of material selected from among a group consisting of sintered substances of hydroxylapatite, .alpha.-tricalcium phosphate, .beta.-tricalcium phosphate, tetra-calcium phosphate, a single substance of amorphous calcium phosphate, monetite, brushite, 45S4 glass, and a mixture of them.
- 8. A method according to claim 7, further comprising the step of forming said particles, and
- wherein said step of forming said particles includes:
- producing amorphous calcium phosphate by a precipitate method by adding phosphoric acid solution to calcium hydroxide suspension;
- sintering said amorphous calcium phosphate at a predetermined temperature; and
- crushing said sintered amorphous calcium phosphate to select said sintered hydroxylapatite particles using a mesh.
Priority Claims (3)
Number |
Date |
Country |
Kind |
8-276969 |
Sep 1996 |
JPX |
|
9-028266 |
Jan 1997 |
JPX |
|
9-190752 |
Jul 1997 |
JPX |
|
Parent Case Info
This is a divisional of application Ser. No. 08/940,992 filed Sep. 30, 1997, still pending the disclosure of which is incorporated herein by reference.
US Referenced Citations (13)
Divisions (1)
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Number |
Date |
Country |
Parent |
940992 |
Sep 1997 |
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