IMPLANTABLE BLOOD FLOW DEVICE

Information

  • Research Project
  • 6310294
  • ApplicationId
    6310294
  • Core Project Number
    R43HL066891
  • Full Project Number
    1R43HL066891-01
  • Serial Number
    66891
  • FOA Number
  • Sub Project Id
  • Project Start Date
    8/15/2001 - 23 years ago
  • Project End Date
    11/30/2004 - 20 years ago
  • Program Officer Name
    ALTIERI, FRANK
  • Budget Start Date
    8/15/2001 - 23 years ago
  • Budget End Date
    11/30/2004 - 20 years ago
  • Fiscal Year
    2001
  • Support Year
    1
  • Suffix
  • Award Notice Date
    8/10/2001 - 23 years ago
Organizations

IMPLANTABLE BLOOD FLOW DEVICE

DESCRIPTION (Unedited Applicant's Abstract): This proposed Phase I effort will evaluate the feasibility of developing an implantable device for telemetric monitoring of blood flow in palliative shunts in children as small as neonates with congenital heart disease. In these patients, these surgically placed shunts represent a lifeline through which all pulmonary circulation flows. Further, an imbalance between pulmonary and systemic blood flow in these patients due to stenosis of the shunt, growth of the patient, or inappropriate systemic or pulmonary vascular resistance can be life-threatening. We believe that serial quantitative measurements of volume shunt flow will lead to improved management of these patients and will result in reduced mortality, morbidity, and cost of care. Currently, the only method available to measure quantitative flow in these shunts is angiography, an invasive procedure that is suitable only in limited circumstances. As part of this effort, we will evaluate the feasibility of implementing the proposed device using an innovative flexible and adaptable architecture that has broad application for telemetering not only blood flow, but blood pressure, ECG, temperature, and cardio thoracic other signals. A highly qualified DSI staff and surgeon will team to investigate this new technology and to establish the potential for Phase II and Phase III success. PROPOSED COMMERCIAL APPLICATION: Successful completion will build the foundation for implementation of a valuable new tool for chronic clinical assessment of blood flow in human beings. Such a tool is currently unavailable and without precedence. Moreover, sucess in this effort should lead to development of additional telemetry devices for key human health applications.

IC Name
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
  • Activity
    R43
  • Administering IC
    HL
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    134467
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    837
  • Ed Inst. Type
  • Funding ICs
    NHLBI:134467\
  • Funding Mechanism
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    TRANSOMA MEDICAL
  • Organization Department
  • Organization DUNS
  • Organization City
    ST. PAUL
  • Organization State
    MN
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    55126
  • Organization District
    UNITED STATES