Claims
- 1. A compound represented by formula (I): wherein R1 represents a halogen atom; a lower alkyl group having 1-6 carbon atoms; a lower alkoxy group having 1-6 carbon atoms; a hydroxyl group; a nitro group; a trifluoromethyl group; a lower alkylthio group; a carbonyl group which is substituted by a hydrogen atom, a lower alkyl group, a carbocyclic aryl group having 6-14 carbon atoms, a lower alkoxy group or an amino group; a carboxyl group; a mercapto group; or a substituted or unsubstituted amino group;R2 represents a hydrogen atom; a substituted or unsubstituted lower alkyl group having 1-6 carbon atoms; a substituted or unsubstituted lower alkenyl group having 2-6 carbon atoms; a substituted or unsubstituted lower alkynyl group having 2-6 carbon atoms; a substituted or unsubstituted lower alkoxy group having 1-6 carbon atoms; a substituted or unsubstituted carbonyl group which is substituted by a hydrogen atom, an alkyl group, a carbocyclic aryl group having 6-14 carbon atoms, a lower alkoxy group or an amino group; a substituted or unsubstituted aryl group having 6-14 carbon atoms; R3 represents a substituted or unsubstituted lower alkyl group having 1-6 carbon atoms; a substituted or unsubstituted cycloalkyl group having 3-8 carbon atoms; a substituted or unsubstituted aryl group having 6-14 carbon atoms; a menthyl group or an adamantyl group; R4 represents —OR5; —SR5; or —NR6R7, wherein R5 and R6 each represent a substituted or unsubstituted pyridyl group and R7 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted cycloalkyl group having 3 to 6 carbon atoms, a substituted or unsubstituted aryl group selected from the group consisting of phenyl and naphthyl, a lower alkoxy group or a substituted or unsubstituted amino group; X and Y, which may be the same or different, each represent —CH2—, —NH— or —O—; and n represents an integer of from 0 to 4; wherein the substituents in the definition of R1 to R7 represent a halogen atom; a lower alkyl group having 1-6 carbon atoms; a C3-C8 cycloalkyl group; a C6-C14 aryl group; a hydroxyl group; a lower alkoxy group having 1-6 carbon atoms; a C6-C14 aryloxy group; a lower alkylthio group; —CH(OR′)2, wherein R′ represents a lower alkyl group having 1-6 carbon atoms; a lower alkylcarbonyl group; a C6-C14 arylcarbonyl group; a carboxyl group; a lower alkoxycarbonyl group; an amino group which may be substituted with one to two methyl groups, an ethyl group or a trifluoromethylcarbonyl group; an imino group; —CR″(SR′)2, wherein R′ and R″ represent a lower alkyl group having 1-6 carbon atoms; a nitro group; a nitrile group; or a trifluoromethyl group; or a salt thereof or an optically active isomer thereof.
- 2. A compound or a salt thereof or an optically active isomer according to claim 1, wherein, in the general formula (I),R1 represents a methyl group; R2 represents a substituted or unsubstituted lower alkyl group; R3 represents a substituted or unsubstituted aryl group having 6-14 carbon atoms; R4 represents —NR6R7, wherein R6 represents a substituted or unsubstituted pyridyl group and R7 represent a hydrogen atom; X and Y, which may be the same or different, each represent —CH2— or —NH—; and n represents 0 or 1.
- 3. An optically active isomer of a compound according to claim 1, or a salt thereof.
Priority Claims (2)
Number |
Date |
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5-67297 |
Feb 1993 |
JP |
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5-167262 |
May 1993 |
JP |
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Parent Case Info
This application is a divisional application of application Ser. No. 08/963,547, filed on Nov. 3, 1997, now U.S. Pat. No. 5,932,511; which is a continuation application of application Ser. No. 08/448,579, filed on Jun. 6, 1995, now abandoned; which is the §371 national application of PCT International Application No. PCT/JP94/00235, filed on Feb. 17, 1994. The entire contents of each of the above-identified applications is hereby incorporated by reference.
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Continuations (1)
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Parent |
08/448579 |
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Child |
08/963547 |
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