Claims
- 1. An assembly for delivering a therapeutic substance to a treatment site within bone, the assembly comprising
a cannula, a catheter, a balloon carried by the catheter and insertable into bone by means of passing the catheter through the cannula, said balloon comprising a wall having an outer surface and being capable of inflation from a collapsed configuration and being sized in the collapsed configuration for passage along with the catheter through the cannula for insertion into bone, to an expanded configuration which has a predetermined shape and size sufficient for compressing at least a portion of inner cancellous bone and which is restrained while being expanded in the presence of the cancellous bone, and a therapeutic substance carried on the outer surface of the balloon wall to be incorporated into the cancellous bone by inflation of the balloon.
- 2. The assembly of claim 1, further comprising
an applicator for applying the therapeutic substance to the outer surface of the balloon wall.
- 3. The assembly of claim 2 wherein the applicator comprises a container having a reservoir of the therapeutic substance and a nozzle for dispensing the therapeutic substance onto the outer surface of the balloon wall.
- 4. The assembly of claim 3 wherein the therapeutic substance is a gel formulation.
- 5. The assembly of claim 2 wherein the applicator comprises a dry powder dispenser.
- 6. The assembly of claim 2, wherein the applicator comprises a dispersion device for spraying the therapeutic substance onto the outer surface of the balloon wall.
- 7. The assembly of claim 6 wherein the therapeutic substance is a powdered medicament.
- 8. The assembly of claim 1 wherein the therapeutic substance comprises a bone filling material.
- 9. The assembly of claim 1 wherein the therapeutic substance comprises a bone growth factor.
- 10. The assembly of claim 1 wherein the therapeutic substance comprises an antibiotic.
- 11. The assembly of claim 1 wherein the therapeutic substance comprises a gelatin powder.
- 12. The assembly of claim 11 wherein the therapeutic substance comprises an agent that absorbs body fluid.
- 13. The assembly of claim 11 wherein the therapeutic substance comprises an agent that inhibits flow of body fluid.
- 14. The assembly of claim 11 wherein the therapeutic substance comprises a hemostatic agent.
- 15. The assembly of claim 11 wherein the therapeutic substance is Gelfoam.
- 16. An assembly as in claim 1 wherein expansion of the balloon in cancellous bone is restrained by selected thickened wall portions of the balloon wall.
- 17. An assembly as in claim 1 wherein expansion of the balloon in cancellous bone is restrained by an internal restraint formed in the balloon wall.
- 18. An assembly as in claim 17 wherein the internal restraint comprises a seam in the balloon.
- 19. An assembly as in claim 17 wherein the internal restraint comprises a meshwork.
- 20. An assembly as in claim 17 wherein the internal restraint comprises a woven material.
- 21. An assembly as in claim 17 wherein the internal restraint comprises string.
- 22. An assembly as in claim 1 wherein expansion of the balloon in cancellous bone is restrained by an external restraint formed in the balloon wall.
- 23. An assembly as in claim 22 wherein the external restraint comprises a seam in the balloon.
- 24. An assembly as in claim 22 wherein the external restraint comprises a meshwork.
- 25. An assembly as in claim 22 wherein the external restraint comprises a woven material.
- 26. An assembly as in claim 22 wherein the external restraint comprises string.
- 27. An assembly as in claim 1 wherein the predetermined shape and size of the balloon when in the expanded configuration comprises opposed sides which are restrained to remain essentially flat.
- 28. An assembly as in claim 1 wherein the cannula is a percutaneous cannula.
RELATED APPLICATIONS
[0001] This application is a divisional of copending application Ser. No. 08/799,832, filed Feb. 13, 1997, which is a continuation of application Ser. No. 08/485,394, filed Jun. 7, 1995, now abandoned, which is a continuation-in-part of Ser. No. 08/188,244, filed Jan. 26, 1994, now abandoned.
Divisions (1)
|
Number |
Date |
Country |
Parent |
08799832 |
Feb 1997 |
US |
Child |
10458235 |
Jun 2003 |
US |
Continuations (1)
|
Number |
Date |
Country |
Parent |
08485394 |
Jun 1995 |
US |
Child |
08799832 |
Feb 1997 |
US |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
08188244 |
Jan 1994 |
US |
Child |
08485394 |
Jun 1995 |
US |