Claims
- 1. An aqueous infusion solution comprising 0.015 to 0.5 g of an active compound, said active compound being 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid, per 100 ml of aqueous solution and an amount of at least one physiologically tolerated acid which suffices to dissolve the active compound, wherein there are 1.33 to 2.2 moles per mole of active compound, of the physiologically tolerated acid, the physiologically tolerated acid being selected from the group consisting of hydrochloric acid, methanesulphinc acid, propionic acid, succinic acid, glutaric acid, citric acid, fumaric acid, maleic acid, tartaric acid, glutamic acid, gluconic acid, glucuronic acid, galacturonic acid, ascorbic acid, phosphoric acid, nitric acid, acetic acid, malic acid, L-aspartic acid and lactic acid.
- 2. An infusion solution according to claim 1, containing a mixture of physiologically tolerated acids to dissolve the active compound.
- 3. An infusion solution according to claim 1, wherein the physiologically tolerated acid is selected from the group consisting of lactic acid, hydrochloric acid and mixtures of lactic acid and hydrochloric acid.
- 4. An infusion solution according to claim 1, containing 1.33 to 1.50 mols of lactic acid per mol of active compound.
- 5. An infusion solution according to claim 1, having a pH from 3 to 5.2.
- 6. An infusion solution according to claim 1, having a pH from 3.6 to 4.7.
- 7. An infusion solution according to claim 1, having a pH from 3.9 to 4.5.
- 8. An infusion solution according to claim 1, having a pH from 4.1 to 4.3.
- 9. An infusion solution according to claim 1, which is substantially isotonic.
- 10. An infusion solution according to claim 1, containing 1.33 to 2.2 mols of lactic acid and 0.0 to 0.80 mol of hydrochloric acid per mol of active compound, and relative to 100 ml of solution, 0.6 to 2.2 g of NaCl.
- 11. An infusion solution according to claim 1, containing 1.33 to 1.4 mols of lactic acid and 0.0 to 0.80 mol of hydrochloric acid per mol of active compound, and relative to 100 ml of solution, 0.75 to 1.2 g of NaCl.
- 12. An infusion solution according to claim 1, present in a container in from 40 to 600 ml.
- 13. An infusion solution according to claim 1, wherein the physiologically tolerated acid is lactic acid.
Priority Claims (1)
Number |
Date |
Country |
Kind |
3537761 |
Oct 1985 |
DEX |
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Parent Case Info
This is a continuation of application Ser. No. 917,467, filed Oct. 10, 1986, now abandoned.
Foreign Referenced Citations (1)
Number |
Date |
Country |
0067666 |
Dec 1982 |
EPX |
Non-Patent Literature Citations (3)
Entry |
Chemical Abstracts 102: No. 21, May 27, 1985, p. 11. |
Chemical Abstracts, vol. 103, No. 17, Oct. 28, 1985, p. 19. |
Chemical Abstracts, vol. 105, No. 11, Sep. 15, 1986, p. 10. |
Continuations (1)
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Number |
Date |
Country |
Parent |
917467 |
Oct 1986 |
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