INHIBITION OF BACTERIAL MIGRATION ALONG URINARY CATHETER

Information

• Research Project
• 3490193

• ApplicationId

  3490193

• Core Project Number

  R43AM036206

• Full Project Number

  1R43AM036206-01

• Serial Number

  36206

• FOA Number

• Sub Project Id

• Project Start Date

  8/1/1985 - 39 years ago

• Project End Date

  6/30/1986 - 38 years ago

• Program Officer Name

• Budget Start Date

  8/1/1985 - 39 years ago

• Budget End Date

  6/30/1986 - 38 years ago

• Fiscal Year

  1985

• Support Year

  1

• Suffix

• Award Notice Date

  -

Organizations

• ALBION INSTRUMENTS, A CORP OF UTAH

Urinary tract infections associated with urinary drainage catheters are a significant clinical problem resulting in a prolonged hospital stay and an increased mortality risk. This proposal addresses a feasibility study to determine if surface modification of the catheter will inhibit bacterial migration. The proposed research will test the hypothesis that bacterial migration is a direct function of surface adherence. Five different surface treatments will be applied to silicone rubber urinary catheters to minimize bacterial adhesion. The catheters will be characterized by microscopy, ESCA and contact angle analysis. In vitro bacterial migration will be determined using a migration model developed for Biomaterials International. Stability of the surface treatments will also be evaluated as a function of ethylene oxide sterilization and storage time.

IC Name

• Activity

  R43

• Administering IC

  AM

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  847

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  SSS

• Study Section Name

• Organization Name

  ALBION INSTRUMENTS

• Organization Department

• Organization DUNS

• Organization City

  SALT LAKE CITY

• Organization State

  UT

• Organization Country

  UNITED STATES

• Organization Zip Code

  84116

• Organization District

  UNITED STATES