The present disclosure is generally directed to a cartridge loaded injector, and, more particularly, to an injector compatible for use with cartridges of differing dimensions.
An injector, such as, for example, a drug injector, is typically loaded with a cartridge containing therein a substance to be dispensed. The cartridge may be pre-loaded prior to delivery to a user, or, alternatively, the cartridge may be loaded by the user prior to use. Drug cartridges are manufactured and sold in different sizes and dimensions. Moreover, even cartridges manufactured via the same processes are subject to variations in dimensions, i.e., manufacturing tolerance. One or more of the manufacturing process and the material used to form the cartridges contributes to manufacturing tolerance. For example, glass cartridges are generally formed having lower precision, and, therefore, have greater variation among cartridges than cartridges formed from molded polymer(s) which are generally formed having greater precisions and lower variation among cartridges. Nevertheless, in the pharmaceutical industry, for example, glass cartridges remain more prevalent.
One drawback of conventional injectors is that they are generally manufactured to operate with a particular corresponding cartridge. Moreover, lower precision cartridges intended to work with a particular injector may nevertheless fail to be usable with the injector if formed exhibiting too large a variation from the intended dimensions.
Therefore, it would be advantageous to manufacture an injector configured to be usable with multiple differently dimensioned cartridges and cartridges subject to larger manufacturing tolerances.
Briefly stated, one aspect of the present disclosure is directed to an injector including a body, and an injection needle movably mounted to the body. The injection needle is displaceable between a retracted position and an injection position. A pathway within the body is sized for independently receiving either of a first cartridge or a radially differently dimensioned second cartridge therein. The pathway includes a proximal opening for receiving the first cartridge or the second cartridge therethrough and a coupler mounted at a distal end of the pathway and engageable with the first cartridge or the second cartridge for fluidly connecting the first cartridge or the second cartridge with the injection needle. At least two adapter collars are mounted within the pathway. A first adapter collar of the at least two adapter collars is configured to receive one of the first cartridge or the second cartridge therethrough upon insertion of the first cartridge or the second cartridge into the pathway, and configured to engage a portion of the first cartridge to stabilize the first cartridge within the pathway. A second adapter collar of the at least two adapter collars is configured to receive either of the first cartridge or the second cartridge therethrough upon insertion of the first cartridge or the second cartridge into the pathway, and configured to engage a portion of the second cartridge to stabilize the second cartridge within the pathway.
Another aspect of the present disclosure is directed to an injector including a body and an injection needle movably mounted to the body. The injection needle is displaceable between a retracted position and an injection position. A pathway within the body for receiving a cartridge includes a proximal opening for receiving the cartridge therethrough and a coupler mounted at a distal end of the pathway and engageable with the cartridge for fluidly connecting the cartridge with the injection needle. An adapter collar is mounted within the pathway and configured to receive the cartridge therethrough upon insertion of the cartridge into the pathway and is configured to engage a portion of the cartridge to stabilize the cartridge within the pathway. The adapter collar includes a disk and a plurality of angularly spaced apart cantilevered fingers projecting from the disk. The fingers are oriented in an unbiased, radially inwardly projecting closed position covering the coupler, and the fingers are deflectable distally and radially outwardly relative to one another by the cartridge into an open position exposing the coupler upon advancement of the cartridge through the disk.
Another aspect of the present disclosure is directed to an injector device kit including an injector and a plurality of adapter collars. The injector includes a body and an injection needle movably mounted to the body. The injection needle is displaceable between a retracted position and an injection position. A pathway within the body is sized for independently receiving any one of multiple radially differently dimensioned cartridges. The pathway includes a proximal opening for receiving the cartridge therethrough and a cartridge piercing needle mounted at a distal end of the pathway and projecting into the pathway, the cartridge piercing needle being in fluid communication with the injection needle and engageable with the cartridge for fluidly connecting the cartridge with the injection needle. The plurality of adapter collars are each removably mountable within the pathway, each adapter collar being configured to receive a corresponding one of the multiple radially differently dimensioned cartridges therethrough and engage a portion of the cartridge to stabilize the cartridge within the pathway and substantially co-axially align the cartridge with the cartridge piercing needle. Mounting of a respective adapter collar within the pathway enables usage of the injector with the respective corresponding cartridge.
The following detailed description of aspects of the disclosure will be better understood when read in conjunction with the appended drawings. It should be understood, however, that the invention is not limited to the precise arrangements and instrumentalities shown. In the drawings:
Certain terminology is used in the following description for convenience only and is not limiting. For example, the words “lower,” “bottom,” “upper” and “top” designate directions in the drawings to which reference is made. The words “inwardly,” “outwardly,” “upwardly” and “downwardly” refer to directions toward and away from, respectively, the geometric center of the injector, and designated parts thereof, in accordance with the present disclosure. Unless specifically set forth herein, the terms “a,” “an” and “the” are not limited to one element, but instead should be read as meaning “at least one.” The terminology includes the words noted above, derivatives thereof and words of similar import.
It should also be understood that the terms “about,” “approximately,” “generally,” “substantially” and like terms, used herein when referring to a dimension or characteristic of a component of the invention, indicate that the described dimension/characteristic is not a strict boundary or parameter and does not exclude minor variations therefrom that are functionally similar. At a minimum, such references that include a numerical parameter would include variations that, using mathematical and industrial principles accepted in the art (e.g., rounding, measurement or other systematic errors, manufacturing tolerances, etc.), would not vary the least significant digit.
Referring to the drawings in detail, wherein like numerals indicate like elements throughout, there is shown in
As shown in
In some embodiments, a depressible activation button assembly 22, constructed, for example, from a polymeric or metal material, combinations thereof, or the like, may be movably mounted to the injector main housing 12 and operatively connected to the injection needle 20. The activation button assembly 22 may be translatable, i.e., depressible, along a button axis B (
A biasing member 24 may be operatively connected with the activation button assembly 22 and the injection needle 20 (
In one embodiment, the biasing member 24 may take the form of a coil spring mounted between the needle hub 18 and the activation button assembly 22, i.e., the spring 24 abuts the activation button assembly 22 at one end and abuts the needle hub 18 at an opposing end. In the energy storing state, the coil spring 24 is at least partially compressed. In the energy releasing state, the coil spring 24 expands (relative to the at least partially compressed energy storing state) to drive the needle hub 18 and the injection needle 20 into the injection position thereof. As should be understood by those of ordinary skill in the art, however, the biasing member 24 may alternatively take the form of other members capable of storing and releasing energy. Non-limiting examples include other springs (e.g., torsion or leaf springs), elastic bands, and the like. Alternatively, the biasing member 24 may take the form of an electromechanical or pneumatic actuator configured to apply a translational force onto the injection needle 20 when the activation button assembly 22 is depressed into the actuated position thereof.
The injector body 11 further includes a cartridge door 26 movably, e.g., pivotably, mounted to the injector main housing 12, between an open position (not shown) and a closed position (
The cartridge door 26 further includes a coupler 26c mounted within the interior pathway 26b. In the illustrated embodiment, the coupler 26c takes the form of a cartridge piercing needle 26c, but the disclosure is not so limited. As shown schematically in
As shown in
In one configuration, as shown best in
In one configuration, as shown in
In some embodiments, the adapter collar 30 may also include a plurality of angularly spaced apart cantilevered fingers 36 projecting from the disk 32. In the illustrated embodiment, the adapter collar 30 includes three fingers 36 generally equally angularly spaced apart about the interior of the disk 32, but the disclosure is not so limited. As shown in
As shown in
In one configuration, as shown in
One difference of the adapter collar 30′ over the adapter collar 30 (as shown in the figures) is the addition of a frangible, i.e., intentionally breakable, member 38 connecting the cantilevered fingers 36′ to one another in the closed position thereof. In the illustrated embodiment, the frangible member 38 takes the form of a frangible ring, but the disclosure is not so limited. As shown best in
In one configuration of the adapter collar 30′, one or more of ribs 34′ takes the form of a generally arcuate member extending radially inwardly and distally from the disk 32, having a convex surface thereof facing toward the central axis of the disk 32, but the disclosure is not so limited. Additionally, or alternatively, one or more of the cantilevered fingers 36′ defines a generally S-shaped curvilinear contour, extending radially inwardly and distally from the disk 32 (assisting in cartridge 28 lead in), but the disclosure is not so limited.
As shown best in
In use, an injector 10 includes at least one adapter collar 30, 30′ mounted within the interior pathway 26b, corresponding to a cartridge 28 intended for use with the injector 10 (
In some embodiments, the injector 10 may be configured to be usable with cartridges 28 of different sizes. For example, as shown schematically, in
In one exemplary non-limiting embodiment, the interior pathway 26c may include at least two of the adapter collars 30, 30′ mounted therein (two of the adapter collars 30, 30′ shown in
The first, distal adapter collar 30, 30′ is sized and positioned within the interior pathway 26b to permit advancement of either one of the first cartridge 28′ or the second cartridge 28″ therethrough upon insertion of that cartridge into the interior pathway 26b. As shown in
Similarly, the second, proximal adapter collar 30, 30′ is also sized and positioned within the interior pathway 26b to permit advancement of either one of the first cartridge 28′ or the second cartridge 28″ therethrough upon insertion of that cartridge into the interior pathway 26b. Conversely, however, as shown in
In some embodiments, some of the adapter collars 30, 30′ mounted within the interior pathway 26b, such as, for example, the distal-most adapter collar, may include the plurality of angularly spaced apart cantilevered fingers 36, 36′ projecting from the disk 32 to assist in preventing contact between a user's hands/fingers (or other of a user's body parts) and the cartridge piercing needle 26c, and, therefore, assist in preventing needle stick injuries. Alternatively, all or none of the adapter collars 30, 30′ mounted within the interior pathway 26b may include the cantilevered fingers 36, 36′.
In an alternative exemplary non-limiting embodiment, as shown in
In one configuration, the injector 10 may be provided as a kit with a plurality of adapter collars 30, 30′ removably mountable within the interior pathway 26b. The interior pathway 26b may be configured to receive any one of multiple different dimensioned cartridges 28, i.e., sized and dimensioned to receive the largest of those cartridges 28. Each adapter collar 30, 30′ provided may be configured, i.e., sized and dimensioned, for use with a corresponding one of the multiple differently dimensioned cartridges 28, to engage a portion of the corresponding cartridge 28 (with the ribs 34, 34′ thereof) to stabilize the cartridge 28 within the interior pathway 26b and align the cartridge 28 with the cartridge piercing needle 26c. Alternatively, or additionally, adapter collars 30, 30′ provided may be configured to account for variations between cartridges 28 due to manufacturing tolerances. Accordingly, a user may mount a particular adapter collar 30, 30′ within the interior pathway 26b to enable usage of the injector 10 with the respective corresponding cartridge 28 prior to inserting the corresponding cartridge 28 into the interior pathway 26b.
It will be appreciated by those skilled in the art that changes could be made to the embodiments described above without departing from the broad inventive concept thereof. It is understood, therefore, that this invention is not limited to the particular embodiments disclosed, but it is intended to cover modifications within the spirit and scope of the present invention, as set forth in the appended claims.
This application is a section 371 of International Application No. PCT/US2018/066660, filed Dec. 20, 2018, which was published on Jun. 27, 2019 under International Publication No. WO 2019/126421 A1, which claims priority from U.S. Provisional Patent Application No. 62/609,740, titled “Adapter To Guide Cartridge With Integrated Shield To Protect Septum Puncture Needle From Finger Stick Hazard,” filed on Dec. 22, 2017, the entire contents of which are incorporated herein by reference.
Filing Document | Filing Date | Country | Kind |
---|---|---|---|
PCT/US2018/066660 | 12/20/2018 | WO |
Publishing Document | Publishing Date | Country | Kind |
---|---|---|---|
WO2019/126421 | 6/27/2019 | WO | A |
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