Liquid medications such as children's oral medications are typically packaged as a two-part system including a medication container and separate dosing device. Dosing devices may take the form of a syringe, dropper, spoon, cup, etc. While the two components may be intended for use together, their physical detachment makes their use cumbersome and prone to separation, particularly after the initial use. Because not all dosing devices are compatible for use with all medication containers, separation and loss of a dosing device can lead to a user dosing with an incompatible device, potentially resulting in underdosing or overdosing situations that can be dangerous and negatively impact the efficacy of the medication.
In addition, conventional medication containers and dosing devices are marked with minimal information in terms of the medication compatible for use with the device, terms of use, dosing instructions, etc., further contributing to dosing errors such as underdosing or overdosing.
Accordingly, what is needed is a comprehensive, integrated drug delivery solution that overcomes the disadvantages of prior art systems, and more particularly, a solution in which the medication container and paired delivery device are physically coupled in an easy-to-use and intuitive design marked with all pertinent information necessary to ensure accurate dosing.
To achieve the foregoing and other aspects, in a first embodiment the present invention provides a medication delivery apparatus including a container configured to contain liquid medication, a delivery device rotatably attached and coupled in fluid communication to the container, the delivery device paired for use with the container, and a fluid passageway extending between the container and the delivery device, wherein, in a first operative position of the delivery device with respect to the container liquid medication is transferable from the container to the delivery device through the fluid passageway, and in a second operative position of the delivery device with respect to the container liquid medication is dispensable from the delivery device.
In some embodiments, the delivery device may rotate with respect to the container between the first and second operative positions of the delivery device.
In some embodiments, the apparatus may further include a child-proof cap removably attached to the container, the child-proof cap rotatable relative to the container between a first position closing the fluid passageway and a second position opening the fluid passageway.
In some embodiments, the apparatus may further include a check valve disposed in the fluid passageway permitting liquid medication flow in a direction of the delivery device and preventing liquid medication flow in a direction of the container.
In some embodiments, the first operative position of the delivery device may correspond to an inverted orientation of the container and the second operative position of the delivery device may correspond to an upright orientation of the container.
In some embodiments, the apparatus may further include a coupling element coupling the delivery device to the container, the coupling element defining at least a portion of the fluid passageway therethrough and having spaced first and second stops, wherein the delivery device is rotationally constrained between the spaced first and second stops, and wherein positioning the delivery proximate the first stop positions the delivery device in the first operative position and positioning the delivery device proximate the second stop positions the delivery device in the second operative position.
In some embodiments, the coupling element may include a first fluid flow passageway therethrough and a second fluid flow passageway therethrough, wherein the first fluid flow passageway is diametrically larger than the second fluid flow passageway, and wherein the delivery device is aligned with the first fluid flow passageway in the first operative position of the delivery device to permit liquid medication flow from the container to the delivery device, and the delivery device is aligned with the second fluid flow passageway in the second operative position of the delivery device to permit air to flow from the container to the delivery device to dispense liquid medication from the delivery device.
In some embodiments, at least one of the container and the delivery device may be marked with a name of a liquid medication contained in the container, a concentration or potency of the liquid medication contained in the container, and at least one set of dosage indicia for dosing a liquid medication according to a manufacturer's recommended dosage.
In some embodiments, the delivery device may be marked with a first set of dosing indicia expressed in a dosage unit of measurement matching a dosage unit of measurement of a concentration of liquid medication in the container, and a second set of dosing indicia expressed as a patient characteristic, and wherein the dosing indicia are expressed as one or more of mL, mg, mcg, IU, m2, age, weight, temperature, or a maximum or a minimum of any one of mL, mg, mcg, IU, m2, age, weight and temperature.
In some embodiments, the apparatus may include a pump sprayer for pumping liquid medication from the container to the delivery device and/or dispensing liquid medication from the delivery device, the pump sprayer configured to direct fluid medication through the fluid passageway when the container is inverted and air through the fluid passageway when the container is upright.
In some embodiments, the delivery device may be in the form of a syringe, a spoon, a barrel, a pipette, a dropper or a cup.
In another embodiment, the present invention provides a medication delivery apparatus including a container containing liquid medication, a delivery device removably attached to the container, and a fluid passageway extending between the container and the delivery device, wherein, in a first operative position of the medication delivery apparatus the liquid medication is transferable from the container to the delivery device through the fluid passageway, and in a second operative position of the medication delivery apparatus the liquid medication is dispensable from the delivery device.
In some embodiments, the apparatus may include a child-proof cap removably attached to the container, the child-proof cap rotatable with respect to the container between a first position closing the fluid passageway and a second position opening the fluid passageway.
In some embodiments, the apparatus may include a check valve disposed in the fluid passageway allowing liquid medication flow in a direction of the delivery device and preventing liquid medication from in a direction of the container.
In some embodiments, the first operative position of the medication delivery apparatus may correspond to an inverted orientation of the container and/or a first rotational position of the delivery device, and the second operative position of the medication delivery apparatus may correspond to an upright orientation of the container and/or a second rotational position of the delivery device.
In some embodiments, the apparatus may include a coupling element coupling the delivery device to the container, the coupling element defining at least a portion of the fluid passageway therethrough and having spaced first and second stops, the delivery device rotationally constrained between the spaced first and second stops, and wherein positioning the delivery proximate the first stop positions the delivery device in the first operative position and positioning the delivery device proximate the second stop positions the delivery device in the second operative position, the coupling element including a first fluid flow passageway therethrough and a second fluid flow passageway therethrough, wherein the first fluid flow passageway is diametrically larger than the second fluid flow passageway, and wherein the delivery device is aligned with the first fluid flow passageway in the first operative position of the delivery device to permit the liquid medication to flow from the container to the delivery device, and the delivery device is aligned with the second fluid flow passageway in the second operative position of the delivery device to permit air to flow from the container to the delivery device to dispense the liquid medication from the delivery device.
In some embodiments, at least one of the container and the delivery device may be marked with a name of the liquid medication contained in the container and a concentration or potency of the liquid medication contained in the container, and wherein the delivery apparatus is marked with at least one set of dosage indicia for dosing the liquid medication according to a manufacturer's recommended dosage.
In another embodiment, the present invention provides a medication delivery apparatus including a container, a delivery device removably attached to the container, and a fluid passageway extending between the container and the delivery device, wherein, when the delivery device is attached to the container, fluid is transferable from the container to the delivery device through the fluid passageway, and wherein fluid is dispensable from the delivery device when the delivery device is attached to the container or detached from the container.
In some embodiments, at least one of the container and the delivery device may be required to be positioned in a first orientation to transfer fluid from the container to the delivery device, and may be required to be in a second orientation different from the first to dispense fluid from the delivery device.
In some embodiments, the apparatus may include a cap attached to the container, the cap rotatable relative to the container between a first position closing the fluid passageway and a second position opening the fluid passageway.
Embodiments disclosed herein may include one or more or any combination of the above features and aspects.
Implementations of the embodiments disclosed herein may be better understood when consideration is given to the following detailed description thereof. Such description makes reference to the included drawings, which are not necessarily to scale, and in which some features may be exaggerated and some features may be omitted or may be represented schematically in the interest of clarity. Like reference numerals in the drawings may represent and refer to the same or similar element, feature, or function. In the drawings:
Embodiments of the invention are described hereinafter with reference to the accompanying drawings in which non-limiting examples are shown. Embodiments of the invention are generally directed to medication delivery apparatus including a medication container configured to contain a volume of liquid medication and a delivery device physically connected and fluidly coupled to the container such that the liquid medication can be transferred from the container to the delivery device. Once a predetermined dose is transferred to the delivery device, the medication can be administered to a patient via the delivery device through the flow of gravity or from evacuation force from the medication container. The apparatus may include a check valve or other flow-control mechanism to prevent backflow from the delivery device into the container. The container may contain a volume of liquid medication greater than a maximum volume of the delivery device such that the apparatus can be used to administer multiple doses. The delivery device may be permanently attached to the container or may be removably attached to facilitate removal for cleaning.
The delivery device 104 may be rotatably coupled to the container 102 such that the delivery device can be rotated to open and close the fluid passageway and/or for filling the delivery device or for dispensing liquid medication from the delivery device. In one example, in a first operative position of the delivery device 104 with respect to the container 102, liquid medication can be transferred from the container to the delivery device through the fluid passageway and is prevented from being dispensed from the delivery device, and in a second operative position of the delivery device 104 with respect to the container 102, liquid medication can be dispensed from the delivery device and is prevented from being transferred from the delivery device to the container through the fluid passageway.
As described further below, the delivery device 104 may have various forms and may be marked with dosage indicia corresponding to recommended dosages for the predetermined medication. As shown in
The delivery device 104 may be coupled to the container 102 through a coupling element 106 defining and/or controlling at least a portion of flow through the fluid passageway. A cap 108, such as a child-proof cap, may be removably attached to the container 102 and may rotate between a first position closing the fluid passageway and a second position opening the fluid passageway. The container 102 may be a resiliently deformable plastic bottle or the like. At least one of the container 102 and the delivery device 104 may be marked with the name of the predetermined medication, concentration of the predetermined medication, potency of the predetermined medication, manufacturer's recommended dosages for the predetermined medication, dosage schedules for the predetermined medication, among other markings and information.
As shown in
The coupling element 106 may further include spaced first and second stops 124, 126 for rotationally constraining the delivery device with respect to the coupling element. In the non-limiting example shown, the first and second stops 124, 126 in the form of shoulders may be provided on a face of the coupling element in spaced-apart relation facing the delivery device. When assembled, the delivery device 104 is installed between the first and second stops 124, 126 and the two stops limit rotation of the delivery device with respect to the coupling element. In use, the delivery device 104 is rotated into position against the first stop 124 to align the larger opening 120 through the coupling element 106 with the fluid passageway of the delivery device to allow liquid to be passed into the delivery device, and the delivery device is rotated into position against the second stop 126 to align the smaller opening 122 through the coupling element 106 with the fluid passageway of the delivery device to allow air to be passed into the delivery device. Thus, the openings 120, 122 and stops 124, 126 correspond to first and second operative positions of the delivery device 104.
In each of the embodiments disclosed herein, the delivery device 104 may be provided in the form including, but not limited to, a syringe, a spoon, a barrel, a pipette, a dropper or a cup.
Indicia marked on any of the container and the delivery device may include at least one of medication name, patient type, oral suspension, brand name of the medication, ingredients, flavor, volume and dosage. Dosages may be expressed in any unit, with or without graduated markings, and in discrete amounts or expressed as ranges.
The embodiments disclosed herein provide an integrated medication delivery apparatus. The apparatus includes active and passive safety features to enable enhanced convenience, safety and accuracy during the preparation and administration of liquid medications. The apparatus is configured to deliver the correct predetermined dose of medication to a specific patient characteristic, such as weight, body surface area (BSA), body mass index (BMI), age, temperature, or in parallel through a specific drug potency, solely through the integrated medication container and correlated delivery device. The integrated delivery device provides intuitive measurement indicia displaying the correct dosing for a multitude of patient characteristics or other dosing modes or preferences, all without any additional calculations or correlations necessary.
The apparatus allows a user to manually control the amount of liquid medication transferred to the delivery device, and thereafter deliver that measured amount to the patient. Liquid medication may be transferred from the medication container to the delivery device by one or more of compression of the container (e.g. squeezing), pressure, pumping, suction, compressed air or other energy source.
In some embodiments, the delivery device may be detachable from the medication container for cleaning or packaging, and may attach to the container via threads, snap-fit engagement, friction fittings, among other attachment mechanism. In some embodiments, the delivery device and the point of attachment of the delivery device to the container may be keyed to prevent an unpaired delivery device from being used with a medication container. Keying may include a key on the delivery device and keyway on the container, or vice-versa, the key and keyway permitting attachment of only a paired delivery device and in a predetermined orientation.
In some embodiments, the delivery device may be moved, rotated, turned or otherwise positioned while connected to the medication container such that the flow of liquid medication from the medication container is restricted from flowing outside of the medication container.
In some embodiments, the apparatus may further include a dedicated mechanism for opening and closing the fluid passageway, such as a valve, lever, stopcock, etc.
In some embodiments, the apparatus is configured with an adjustable actuator to transfer a predetermined amount of liquid medication from the container to the delivery device, such as a metered dose corresponding to a manufacturer's recommend dose.
In some embodiments, the delivery device may be permanently or removably attached to the container, and the configuration thereof may be changed for filling or dispensing.
The foregoing description provides embodiments of the invention by way of example only.
Number | Name | Date | Kind |
---|---|---|---|
844686 | Marschall | Feb 1907 | A |
2768660 | Russell | Oct 1956 | A |
4079859 | Jennings | Mar 1978 | A |
4214679 | Whang | Jul 1980 | A |
4865230 | Tugwood | Sep 1989 | A |
5020699 | Sams | Jun 1991 | A |
5271538 | Lipker | Dec 1993 | A |
5337926 | Drobish et al. | Aug 1994 | A |
6378735 | Chu | Apr 2002 | B1 |
7025232 | Green | Apr 2006 | B2 |
20010050242 | Kaplan | Dec 2001 | A1 |
20060163187 | Kopinetz | Jul 2006 | A1 |
20080149638 | Van Hees et al. | Jun 2008 | A1 |
20090143745 | Langan | Jun 2009 | A1 |
20120000592 | Mase | Jan 2012 | A1 |
20130204225 | Creaturo | Aug 2013 | A1 |
Number | Date | Country |
---|---|---|
2915971 | Nov 2008 | FR |
Entry |
---|
International Search Report for International Application No. PCT/US19/67792 dated Mar. 25, 2020. |
Number | Date | Country | |
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20200197260 A1 | Jun 2020 | US |
Number | Date | Country | |
---|---|---|---|
62782831 | Dec 2018 | US |