Claims
- 1. A compound having the formula:
- 2. A compound having the formula:
- 3. A compound having the formula:
- 4. A compound having the formula:
Parent Case Info
This application is a continuation of and claims priority from United States patent application 09/334,488, filed Jun. 16, 1999, which claims priority from United States provisional patent application 60/089,682, filed Jun. 17, 1998.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
5338865 |
Kishi et al. |
Aug 1994 |
A |
5436238 |
Kishi et al. |
Jul 1995 |
A |
Foreign Referenced Citations (2)
Number |
Date |
Country |
0 572 109 |
Dec 1993 |
EP |
WO 9317690 |
Sep 1993 |
WO |
Non-Patent Literature Citations (3)
Entry |
Aicher et al., “Total Synthetic of Halichondrin B and Norhalichondrin B,” J. Am. Chem. Soc. 114:3162-3164 (1992). |
Horita et al., “Synthesis Studies of Halichondrin B, and Antitumor Polyether Macrolide Isolated from a Marine Sponge. 8. Synthesis of the Lactone Part (C1-C36) via Horner-Emmons Coupling Between C1-C15 and C16-C36 Fragments and Yamaguchi Lactonization,” Tetrahedron Letters 38:8965-8968 (1997). |
Stamos et al., “New Synthetic Route to the C.14-C.38 Segment of Halichondrins,” J. Org. Chem. 62:7552-7553 (1997). |
Provisional Applications (1)
|
Number |
Date |
Country |
|
60/089682 |
Jun 1998 |
US |
Continuations (1)
|
Number |
Date |
Country |
Parent |
09/334488 |
Jun 1999 |
US |
Child |
09/677485 |
|
US |