Claims
- 1. A compound of Formula ##STR17## where R is a methylthio, methylsulfoxy, methylsulfonyl or a nitro group;
- X1 and X2 together are an oxygen atom;
- X3 is hydrogen or --CO--R4 where R4 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 haloalkyl, C.sub.3-6 cycloalkyl, phenyl or phenylalkyl(C.sub.1-6) where the phenyl ring may be substituted by one or two halogen, C.sub.1-3 alkyl, C.sub.1-3 alkoxy or nitro; and
- X4 is OCOAlkyl(C.sub.1-4) or --O--SO.sub.2 R6 where R6 is methyl, trifluoromethyl, phenyl or p-methyl-phenyl.
- 2. The compound of claim 1, which is in the D-threo form.
- 3. The compound of claim 1, wherein X3 is H.
- 4. A compound of Formula ##STR18## where R is a methylthio, methylsulfoxy, methylsulfonyl or a nitro group;
- X1 and X2 together are an oxygen atom;
- X3 is hydrogen or --CO--R4 where R4 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 haloalkyl, C.sub.3-6 cycloalkyl, phenyl or phenylalkyl(C.sub.1-6) where the phenyl ring may be substituted by one or two halogen, C.sub.1-3 alkyl, C.sub.1-3 alkoxy or nitro; and X4 is fluorine.
- 5. The compound of claim 4, which is in the D-threo form.
- 6. The compound of claim 4, wherein X3 is H.
- 7. 5-(4-methylsulfonylphenyl)-4-fluoromethyl-oxazolidin-2-one.
Priority Claims (2)
Number |
Date |
Country |
Kind |
21417 A/83 |
Jun 1983 |
ITX |
|
22449 A/83 |
Aug 1983 |
ITX |
|
Parent Case Info
This is a division of application Ser. No. 07/162,247 U.S. Pat. No. 5,105,009, filed Feb. 29, 1988, which is a continuation of Ser. No. 06/616,086 now abandoned, filed Jun. 1, 1984.
US Referenced Citations (12)
Foreign Referenced Citations (6)
Number |
Date |
Country |
179022 |
Jul 1954 |
ATX |
876750 |
Jul 1971 |
CAX |
0014437 |
Aug 1980 |
EPX |
0130633 |
Jan 1985 |
EPX |
423705 |
Apr 1991 |
EPX |
1058523 |
Sep 1952 |
DEX |
Non-Patent Literature Citations (6)
Entry |
Merck Index, 10th Ed., Merck & Co., Rahway, N.J. 1983, pp. 289 and 1332. |
Giordano et al. Jour. Org. Chem. vol. 56 pp. 6114-6118 (Oct. 1991). |
Villa et al. Chem. Abstr. vol. 115, entry 71094n abstracting EP 423705. |
Greene and Wuts, "Protective Groups in Organic Synthesis", 2nd Ed., pp. 31-34, 36-38, and 68-86. |
Jommi et al., Gazetta Chimica Italiana, vol. 118, pp. 75-76, (1988). |
Jommi et al., Gazzetta Chimica Italiana, vol. 116, pp. 485-489 (1986). |
Divisions (1)
|
Number |
Date |
Country |
Parent |
162247 |
Feb 1988 |
|
Continuations (1)
|
Number |
Date |
Country |
Parent |
616086 |
Jun 1984 |
|