Claims
- 1. A (4R)-[3-[2-(ω-substituted alkyl)-3-(R)-hydroxy-1-oxo-3-(2S,4R)-2-pyrrolidinyl]propyl]-oxazolidin-2-one (or thiazolidine-2-thione) compound represented by the formula (I): wherein R1 is selected from the group consisting of methylsulfonyl, ethylsulfonyl, propylsulfonyl, phenylsulfonyl, p-toluenesulfonyl, trimethylsilyl, triethylsilyl, isopropyldimethylsilyl, t-butyldimethylsilyl, t-butyldiphenylsilyl and vinyldimethylsilyl; R2 is a protecting group selected from the group consisting of formyl, acetyl, chloroacetyl, dichloroacetyl, propionyl, phenylacetyl, thienylacetyl, t-butoxycarbonyl, benzyloxycarbonyl, p-nitrobenzyloxycarbonyl, p-methoxybenzyloxycarbonyl, p-bromobenzyloxycarbonyl and 2,4-dichlorobenzyloxycarbonyl; R3 is a substituted or unsubstituted lower alkyl group or an aryl group; X is an oxygen atom or a sulfur atom; Y is an azide group or a nitro group; and n is an integer of 1 to 4.
- 2. The compound as claimed in claim 1, wherein X is an oxygen atom.
- 3. The compound as claimed in claim 1, wherein Y is an azide group.
- 4. The compound as claimed in claim 1, wherein n is 2.
Priority Claims (1)
Number |
Date |
Country |
Kind |
9-133171 |
May 1997 |
JP |
|
Parent Case Info
This is a division of Ser. No. 09/423 825, filed Nov. 12, 1999 which is a 371 of PCT JP/9802225/ filed May 21, 1998.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
6037341 |
Sato et al. |
Mar 2000 |
A |
Foreign Referenced Citations (1)
Number |
Date |
Country |
97102555 |
Mar 1997 |
WO |
Non-Patent Literature Citations (1)
Entry |
“ER-35786” Drugs of the Future, Barcelona, Es, vol. 21, No. 4, 1996, pp 361-365 XP-000917207. |