Example embodiments are directed to an irradiation target encapsulation assembly and/or method for assembling an irradiation target encapsulation assembly.
Radioisotopes have a variety of medical applications stemming from their ability to emit discreet amounts and types of ionizing radiation. This ability makes radioisotopes useful in cancer-related therapy, medical imaging and labeling technology, cancer and other disease diagnosis, medical sterilization, and a variety of other industrial applications.
Radioisotopes, having specific activities are of particular importance in cancer and other medical therapy for their ability to produce a unique and predictable radiation profile. Knowledge of the exact amount of radiation that will be produced by a given radioisotope permits more precise and effective use thereof, such as more timely and effective medical treatments and improved imaging based on the emitted radiation spectrum.
Medical radioisotopes are conventionally produced by bombarding stable parent isotopes in accelerators, cyclotrons or low-power reactors on-site at medical facilities or at production facilities. The produced radioisotopes may be assayed with radiological equipment and separated by relative activity into groups having approximately equal activity in conventional methods.
In one embodiment, an irradiation target encapsulation assembly, includes a container, at least one first irradiation target disposed in the container, at least one second irradiation target disposed in the container, and a positioning structure configured to position the first irradiation target closer to an axial center of the container than the second irradiation target.
The first irradiation target may be a material including at least one of cobalt (Co), chromium (Cr), copper (Cu), erbium (Er), germanium (Ge), gold (Au), holmium (Ho), iridium (Ir), lutetium (Lu), molybdenum (Mo), palladium (Pd), samarium (Sm), thulium (Tm), ytterbium (Yb), and yttrium (Y).
The second irradiation target may be a material including at least one of cobalt (Co), chromium (Cr), copper (Cu), erbium (Er), germanium (Ge), gold (Au), holmium (Ho), iridium (Ir), lutetium (Lu), molybdenum (Mo), palladium (Pd), samarium (Sm), thulium (Tm), ytterbium (Yb), and yttrium (Y).
In one embodiment, the positioning structure includes a central body extending along the axis of the container, and a spacing structure configured to position the central body along an axis of the container. For example, the spacing structure may include a plurality of projections projecting from the central member. In another embodiment, the spacing structure includes one or more members connected to the central body and having a periphery matching an inner periphery of the container. In these embodiments, the second irradiation target is disposed next to one end of the central body, and the first irradiation target is disposed between the central body and the container. A length of the central body may be based on a desired specific activity resulting from irradiating the second irradiation target. Still further, a cross sectional area of the central body may be based on a desired specific activity resulting from irradiating the first irradiation target.
In another embodiment, the positioning structure has a cross-sectional area that varies along a length thereof to create different sized spaces between the positioning structure and the container for holding multiples of the first irradiation target.
One embodiment of a method for assembling an irradiation target encapsulation assembly, includes placing a position structure within a container and adding a plurality of first irradiation targets to the container. The positioning structure is configured to position the first irradiation targets between the positioning structure and the container. Next, at least one second irradiation target is added to the container. The positioning structure is configured to position the second irradiation target at the end of the position structure. The container is then sealed.
Example embodiments will become more apparent by describing, in detail, the attached drawings, wherein like elements are represented by like reference numerals, which are given by way of illustration only and thus do not limit the example embodiments herein.
Detailed illustrative embodiments of example embodiments are disclosed herein. However, specific structural and functional details disclosed herein are merely representative for purposes of describing example embodiments. The example embodiments may, however, be embodied in many alternate forms and should not be construed as limited to only example embodiments set forth herein.
It will be understood that, although the terms first, second, etc. may be used herein to describe various elements, these elements should not be limited by these terms. These terms are only used to distinguish one element from another. For example, a first element could be termed a second element, and, similarly, a second element could be termed a first element, without departing from the scope of example embodiments. As used herein, the term “and/or” includes any and all combinations of one or more of the associated listed items.
It will be understood that when an element is referred to as being “connected,” “coupled,” “mated,” “attached,” or “fixed” to another element, it can be directly connected or coupled to the other element or intervening elements may be present. In contrast, when an element is referred to as being “directly connected” or “directly coupled” to another element, there are no intervening elements present. Other words used to describe the relationship between elements should be interpreted in a like fashion (e.g., “between” versus “directly between”, “adjacent” versus “directly adjacent”, etc.).
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments. As used herein, the singular forms “a”, “an” and “the” are intended to include the plural forms as well, unless the language explicitly indicates otherwise. It will be further understood that the terms “comprises,” “comprising,” “includes,” and/or “including,” when used herein, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
It should also be noted that in some alternative implementations, the functions/acts noted may occur out of the order noted in the figures. For example, two figures shown in succession may in fact be executed substantially concurrently or may sometimes be executed in the reverse order, depending upon the functionality/acts involved.
At least some example embodiments are directed to an irradiation target encapsulation assembly structured to produce both high specific activity and low specific activity irradiation targets when exposed to radiation.
A spacer 100 is disposed within the container 110.
As will be appreciated, the rod 108 is not limited to having this shape, but may be a central body having any desired shape or cross-section. Similar, the projecting members positioning the central body within the container are not limited to fins, and will depend on the shape of the central body and the shape of the container 110.
Returning to
During irradiation, the LSA irradiation targets 120 disposed at the ends of the container 110 will experience a lower radiation level than the high specific activity targets 130 discussed below. As used herein “radiation level” or “radiation field” includes any type of ionizing radiation exposure capable of transmuting targets placed in the radiation field, including, for example, high-energy ions from a particle accelerator or a flux of neutrons of various energies in a commercial nuclear reactor.
As further shown in
Still further,
Suitable targets for the LSA and HSA targets may be formed of cobalt (Co), chromium (Cr), copper (Cu), erbium (Er), germanium (Ge), gold (Au), holmium (Ho), iridium (Ir), lutetium (Lu), molybdenum (Mo), palladium (Pd), samarium (Sm), thulium (Tm), ytterbium (Yb), and/or yttrium (Y), although other suitable materials may also be used. In one embodiment, the LSA and HSA targets are not nuclear fuel. In one embodiment the LSA and HSA targets are formed of the same material. In another embodiment, the LSA and HSA targets are formed of different materials. As will be appreciated, the differentiation between LSA and HAS differs for different isotopes. For example, for Co-60, LSA is roughly <200 Ci/g, and HSA is roughly >200 Ci/g.
The irradiation target encapsulation assembly discussed above includes a spacer that serves as a positioning structure to position HSA targets toward the axial or longitudinal center of the container 100 and positions the LSA targets towards the axial or longitudinal periphery of the container 100. The container 100 may be placed in any radial orientation and/or axial orientation within a test reactor or a nuclear reactor. In one embodiment, the container 100 may have marking or indicia indicating one or more of desired orientation of the container, the identity of the container, the identity of targets within the container, etc.
The spacer 110 may be sized to thinly spread the HSA targets radially within the container. Accordingly, the diameter of the spacer rod 108 may be selected to achieve a desired thickness of the HSA targets; and thus achieve a desired level of activity. As will be appreciated, in a more general sense, regardless of the shape of the central body 108, the cross-section thereof may be selected to achieve a desired thickness of the HSA targets. The spacer rod 108 may be solid or hollow. In one embodiment, the spacer rod 108 may be made from or include a neutron moderation material (e.g., graphite) and/or a neutron multiplying material (e.g., beryllium). A length of the spacer 110 is selected to position the LSA targets at the desired axial position within the container to achieve the desired level of activity. Accordingly, the length of spacer may depend on the reactor flux profile. The spacer 110 may include different sets of fins 102 with the sets rotationally offset from one another or symmetrically aligned.
As a still further alternative, the spacer 100 may be eliminated and the HSA targets may be randomly packed within the container between the LSA targets and/or dividing structures, which divide the HSA targets from the LSA targets.
The above-described features of example embodiment encapsulation assembly and the known radiation profile to which the encapsulation assembly is to be exposed may uniquely enable accurate irradiation of irradiation targets 120 and 130 use therein. For example, knowing an irradiation flux type and profile; a shape, size, and absorption cross-section of irradiation targets 120 and 130; and size, shape, position, and absorption cross-section of the example embodiment encapsulation assembly, and loading positions of the example embodiment encapsulation assembly, one may very accurately position and irradiate targets 120 and 130 to produce desired isotopes and/or radioisotopes of desired activity. Similarly, one skilled in the art can vary any of these parameters, including irradiation target type, shape, size, position, absorption cross-section etc., in example embodiments in order to produce desired isotopes and/or radioisotopes of desired activity. Still further the addition of moderating elements may be used to achieve the desired activity. As mentioned above, moderating material may be used in the spacer rod 108. However, the example embodiments are not limited to using moderating material in this manner. For example, the container 100 may include a liner or partial liner on the inner diameter of the container made of moderating material.
Next an embodiment of a method for assembling an irradiation target encapsulation assembly will be described with respect to
As shown in
As will be appreciated one of method steps S610 and S640 may be eliminated such that LSA target(s) appear at only one end of the spacer 100.
Example embodiments and methods thus being described, it will be appreciated by one skilled in the art that example embodiments may be varied through routine experimentation and without further inventive activity. For example, aspects of the different embodiment may be combined. Similarly, for example, although cylindrical example embodiments are shown, other device types, shapes, and configurations may be used in example embodiments and methods. Variations are not to be regarded as departure from the spirit and scope of the exemplary embodiments, and all such modifications as would be obvious to one skilled in the art are intended to be included within the scope of the following claims.
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Number | Date | Country | |
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20130077725 A1 | Mar 2013 | US |