The present invention relates generally to an isolation shelter or a clean room containing an isolation space and, more particularly, pressurizing an isolation shelter or a clean room containing an isolation space to prevent, or substantially prevent, escape of contaminants from the isolation space to the external environment and entry of contaminants from the external environment into the isolation space.
In the post 9/11 world, there is an increased awareness of the potential of a bioterrorist attack, and also naturally occurring biological or chemical events, that would require the isolation and quarantine of a large number of casualties. The SARS episode, during which two hospitals in Toronto, Canada, became SARS-only facilities that denied medical services to the general public, showed that current healthcare facilities are not prepared to handle a large surge of infectious patients. A potentially imminent viral flu epidemic would require the isolation and treatment of a large population of infectious patients, which could outstrip current healthcare capabilities.
To meet these new threats, the healthcare community needs to have the capability to isolate a large number of patients, and to quarantine a large number of suspected infected patients, to prevent the spread of the disease. The current WHO estimate is that a pandemic, such as may be associated with the avian flu, could result in millions of deaths unless adequate quarantine, isolation and treatment are available. The civilian healthcare community cannot function with the large number of infectious patients that could occur during a bioterrorist attack, such as smallpox, or a natural pandemic, such as avian flu.
An isolation shelter, which may be in the form of a building, room, tent or other like structure and defines an enclosed space, is typically used by the healthcare community to isolate patients. The enclosed space of the shelter, for example, can be maintained at a pressure exceeding the pressure outside the shelter (“positive pressure”), such as by supplying more HEPA and/or charcoal filtered air into the shelter than the air being vented or leaking from the shelter. The positive pressure prevents or substantially prevents airborne toxic contaminates or vapors in the external environment from entering the shelter. Thus, civilians within the enclosed space of an isolation shelter are isolated from any toxic vapor or biological/radiological particulate contamination existing outside of the shelter.
To protect the general population from infectious patients who, for example, may spread disease by coughing or sneezing, infected patients are isolated in the enclosed space of an isolation shelter which is maintained at a pressure that is less than the pressure of the outside environment (“negative pressure”). The negative pressure prevents or substantially prevents any airborne biological contaminate within the shelter from escaping to the external environment. Negative pressure is typically created by removing more air from the enclosed space than is supplied to and/or leaks into the enclosed space. To assist in infection control, the air within a negative pressure shelter may be filtered with a HEPA filter having, for example, a filtration efficiency of 99.99% for >0.3 micron particles at a rate of at least 12 air exchanges per hour.
Therefore, there is a need for an isolation shelter that prevents or substantially prevents contaminants in the environment outside of the shelter from entering an enclosed space defined within the shelter and, in turn, contaminating people or objects contained within the enclosed space; and that prevents or substantially prevents airborne contaminants generated by infectious patients or objects contained within the enclosed space from escaping the shelter into the external environment and, in turn, contaminating the environment outside the shelter.
In accordance with the present invention, an isolation shelter includes an inner enclosure defining an isolation space, and an outer enclosure enclosing a sealed region defined at least in part by a structural element contained within the interior of the shelter. A sealed space, which is partially defined by any portion of the outer enclosure that can become exposed to the environment outside the outer enclosure, in other words, the environment outside the shelter, extends from the outer enclosure into the interior or sealed region of the shelter. A portion of the inner enclosure may also define the sealed space. The sealed space is at a pressure exceeding the pressure of the environment outside of the shelter, or at a positive pressure. The positive pressure in the sealed space prevents or substantially prevents contamination in the environment outside the shelter from entering through the outer enclosure into the sealed space, and then passing from the sealed space into the isolation space directly, or indirectly via an enclosed space(s) disposed intermediate the sealed space and the isolation space. The isolation space is at a pressure less than the pressure of the environment of the interior of the shelter outside the inner enclosure, in other words, at a negative pressure in relation to the sealed space or an intermediate enclosed space at the outside of the inner enclosure. The negative pressure within the isolation space prevents or substantially prevents contaminants from escaping the isolation space, and then passing through the sealed space, or through an intermediate enclosed space and then the sealed space, to the environment outside the isolation shelter.
Preferably, an air blower system including tubing coupled to the sealed space and the isolation space maintains the sealed space and the isolation space under the desired positive and negative pressures, respectively. The air blower system preferably filters any air supplied to the isolation shelter, and also filters any air exiting the isolation shelter before its release to the external environment.
In a preferred embodiment, the isolation shelter includes an entry/egress port in a portion of each of an outer wall of the outer enclosure and an inner wall of the inner enclosure. In still a further preferred embodiment, an air lock system having re-closable ports, for example, doors, at opposing ends constitutes the entry/egress port at an outer wall of the outer enclosure, and one of the re-closable ports opens into the sealed space and the other of the re-closable ports opens into the environment outside of the isolation shelter. In an alternative preferred embodiment, an air lock system extends between an entry/egress port in an outer wall of the outer enclosure and an entry/egress port in an inner wall of the inner enclosure, and the opposing re-closable ports, respectively, open to the environment outside of the isolation shelter and within the isolation space. The air lock system preferably is maintained at a positive pressure and filters the air contained within, and most preferably is at a pressure slightly less than the pressure outside of the shelter.
In a preferred embodiment of the present invention, an isolation shelter includes outer walls sealed to each other and a floor to define an outer enclosure, and inner walls sealed to each other and the same floor to define an inner enclosure contained within the outer enclosure. The region defined between the outer enclosure and the inner enclosure is a sealed, wall space, and the region defined within the inner enclosure is an isolation space. The wall space is maintained under positive pressure in relation to the environment at the outside of the outer enclosure, in other words, outside of the shelter, and the isolation space is maintained under negative pressure in relation to the pressure within the wall space. An air blower system coupled to the wall space and the isolation space maintains the respective spaces under the desired positive and negative pressures, respectively.
Other objects and advantages of the present invention will be apparent from the following detailed description of the presently preferred embodiments, which description should be considered in conjunction with the accompanying drawings in which like references indicate similar elements and in which:
For purposes of highlighting the features of the present invention, an isolation shelter pressurized to prevent or substantially prevent (i) atmospheric contamination in the environment outside the shelter from entering an isolation space within the shelter, and (ii) airborne contaminants within the isolation space from escaping the isolation shelter into the outside environment, is described in detail below in connection with an isolation shelter whose outside environment is the atmosphere of the earth. It is to be understood that the features of the inventive isolation shelter are similarly applicable to portable containers, clean rooms or other enclosed spaces whose outside environment may be other than the earth's atmosphere.
Referring to
In another alternative embodiment, the containers 18 and 20 share wall components. For example, a portion of the ceiling forming the container 18 can be the ceiling from which the container 20 is formed.
Each of the walls 12 and 14 is preferably made of material that is impermeable, or substantially impermeable, to substantially all liquids, solids, such as particulates, and gases, such as air, and can include polymeric material, steel, plaster, or other well known building materials. In addition, the floor 16, like the walls 12 and 14, is preferably made of material impermeable, or substantially impermeable, to substantially all liquids, solids and gases. Further, the seals between the walls, and the walls and the floor, in the shelter 10 are seals that are preferably impermeable, or substantially impermeable, to substantially all liquids, solids and gases. Consequently, a sealed wall space 26 is defined between the container 18 and the container 20, and the space or isolation space 21 enclosed by the container 20 is also a sealed space.
The impermeable seals at all connections of walls to each other or to the floor for each of the containers 18 and 20 prevent unwanted leakage of, for example, contaminants, into and out of the spaces 21 and 26 of the shelter 10.
In accordance with the present invention, any portion of an outer wall of the outer container 18 that can become exposed to the environment outside of the outer container 18 defines the sealed wall space 26. Referring to
In a preferred embodiment, air, which is preferably HEPA and/or charcoal filtered air, is supplied into the wall space 26 to create and maintain positive air pressure in the wall space 26. If the shelter 10 includes doors, windows, or wall cracks in the outer walls 12 through which the pressurized air may leak from the wall space 26 into the environment outside the shelter 10, air is continuously replenished to the wall space 26 to maintain a positive pressure in the space 26.
In addition, in a preferred embodiment, air, which is also preferably HEPA and/or charcoal filtered air, is supplied into the isolation space 21 and air is also exhausted from the space 21. Typically, more air is exhausted from the isolation space 21 than returned to the space 21, so as to maintain a negative pressure in the isolation space 21. The maintenance of positive pressure in the wall space 26 and negative pressure in the isolation space 21 using an air blower system 80 is discussed in detail below in connection with the text accompanying the description of
Referring again to
Still referring to
In operation, the blower system 80 supplies air, which may be processed by decontamination, HEPA filtration and/or charcoal filtration within the system 80, to the isolation space 21 via the port 88, the duct 90 and the pipe 72. In addition, the blower system 80 draws air from the isolation space 21 via the pipe 74, the duct 92 and the inlet port 82. Also, the blower system 80 supplies some of the air returned at the inlet port 82 to the wall space 26 via the outlet port 86, the duct 94 and the port 30C.
The blower system 80 supplies a sufficient amount of air to the outlet port 86 to maintain positive air pressure within the wall space 26. The valve 96 within the duct 94 controls the amount of air supplied to the wall space 26 and, thus, the pressure of the air within the wall space 26. If there is essentially no leakage in the wall space 26, substantially all of the air supplied to the duct 94 will exit through the valve 96. If there is leakage in the wall space 26, such as through an entry/egress port 30, or a wall crack, then little or no air will exit the duct 94 through the valve 96 and most of the air that the blower system 80 supplies to the duct 94 will enter the wall space 26 to maintain the desired positive pressure.
In an alternative embodiment, the valve 96 is omitted from the blower system 80 and the blower system 80, instead, includes a pressure sensor 89 coupled to the duct 94. The sensor 89 determines the pressure within the space 26 by monitoring the pressure in the duct 94 at the outlet port 86, and suitably regulates the volume of air the blower system 80 supplies at the outlet 86 to maintain a desired level of positive pressure within the space 26. The blower 80 draws fresh air from the environment, as needed, through the intake vent 84 for use in the supply of preferably filtered air to the space 26 to maintain positive pressure therein.
As discussed above, some of the air drawn from the isolation space 21 exits the blower 80 at the outlet 86, such that the withdrawn air is not returned to the isolation space 21. The blower system 80 creates and maintains negative pressure in the isolation space 21 by providing that the amount of air withdrawn from the space 21 exceeds the amount of air supplied to the space 21.
In a preferred embodiment, the blower system 80 includes conventional pressure sensors 91 and 93 at the inlet 82 and the outlet 88, respectively, which monitor the flow of air through the ports 82 and 88. In a further embodiment, the sensors 91 and 93 act as regulators that open and close the individual ports 82 and 88 to maintain a negative pressure in the isolation space 26. Alternatively, the sensors 91 and 93 provide data representative of the pressure in the isolation space 26 to a conventional controller (not shown) within the blower system 80. The controller controls the volume of air supplied to the port 88, with or without opening or closing the port 88, and also controls the opening and closing of the port 82, to maintain a desired pressure in the isolation space. In another embodiment, one or more of the sensors 89, 91 and 93 are located within the spaces 21 and 26 and can communicate pressure data to the controller in the blower system 80 via wires (not shown), or wirelessly.
The blower system 80 can be any conventional air blowing system operable, in connection with the isolation shelter 10, to supply filtered air at the outlet 86 to create and maintain positive pressure in the space 26; to supply a sufficient amount of filtered air at the outlet 88, in relation to the amount of the air received at the inlet 82 from the space 21, to create and maintain negative pressure at the isolation space 21; and to receive air at the inlet 84, as necessary, for use in supplying filtered air at the outlet 86 to maintain positive pressure in the space 26 and, optionally, for use in supplying air at the outlet 88 as needed.
It is to be understood that commercial blowers and filtration devices may be readily adapted for use in the blower system 80 to supply air from two outlets, as well as to provide the air flows needed to create the desired positive and negative pressures in the isolation shelter 10. In a preferred embodiment, the blower system 80, for example, includes a HEPA and/or a charcoal filter coupled to the air stream of a blower that supplies air to the ports 86 and 88. In another preferred embodiment, the blower system 80 is part of an air decontamination device, such as that disclosed in U.S. patent application Ser. No. 10/434,041, filed on May 8, 2003 and published as U.S. Patent Publication No. U.S. Patent Publication No. 2004/0146437 Al on Jul. 29, 2004, or part of an air decontamination, heating, ventilation, and air conditioning device (“ADHVAC”), which is described in U.S. patent application Ser. No. 11/089,795, which was filed on Mar. 3, 2005 and was published as U.S. Patent Publication No. 2005/0211415 Al on Sep. 29, 2005, each of which is incorporated by reference herein.
In a preferred embodiment, the air in the wall space 26 is maintained at a positive pressure that meets the military Collective Protection requirement of 0.5 inches water column over pressure, and the isolation space 26 is maintained at a negative pressure of at least 0.01 inches water column less than the ambient air pressure outside the shelter 10.
Referring to
In another embodiment, both doors of the passageway of the system 130A or 130B can be opened at once, although such implementation is not very desirable because the chances for transfer of contaminants between the isolation space 21 and the outside environment, in either direction, increases.
In a preferred implementation of the shelter 10, the isolation space 26 is occupied by a patient. By maintaining a negative pressure in the isolation space 21, the filtered air maintains a proper oxygen level and reduces CO2 buildup to enable safe human occupation of the space 26. The shelter 10, thus, provides that CDC guidelines for airborne infection isolation or protective isolation can be maintained through use of a suitable blower system in connection with the shelter 10. The air within the isolation space 21 can be recirculated through a HEPA filter to generate the desired air exchanges per hour (12 air changes per hour (“ACH”) for isolation and 15 ACH for surgery) for the removal of infectious patient-generated airborne contaminates. The recirculating air would also be environmentally controlled to maintain a comfortable living space (temperature and humidity) in the space 21, independent of the ambient outside environment. The negative pressure of >0.01 water column can be controlled by the filtered exhaust air flow.
Still referring to
The container 120 of the shelter 110 contains an inner container 20 enclosing an isolation space 21. The inner enclosure 20 includes four lateral inner walls 14A, of which one wall 14A constitutes a portion of one of the walls 102. As in the shelter 10, the walls 14, an inner wall ceiling 14B and a portion of the floor 16 to which the walls 14A are sealed forms the isolation space 26. An intermediate, sealed space 126, thus, is defined between the inner container 20 and the container 120.
In the embodiment of the shelter 110 illustrated in
Referring to
In operation of the shelter 110, the positive pressure in the space 26 prevents or substantially prevents contaminants at the outside of the wall 12A of the shelter 110 from entering the space 126 and, ultimately, passing into the isolation space 21. In addition, the negative pressure in the space 21 prevents or substantially prevents contaminants in the space 21 from entering the space 126 via leaks or cracks in any of the walls 14, which partially define the space 126 and, thus, are in contact with the environment of the space 126. Thus, the negative pressure in the space 21 provides that contaminants in the space 21 would not escape into the space 126, pass from the space 126 through the wall 102A that defines the enclosure 112, then through the space 26 and into the outside environment.
In a preferred embodiment, the inventive isolation shelter includes a solid wall enclosure, such as a room, within a fixed structure, such as a building, or an ISO-container or other solid wall portable enclosure.
The liners 112 and 114 preferably are made of fabric or other suitable material having the above-described solid, liquid and gas impermeability qualities. The outer liner 112 may be constructed of a chemical warfare (CW) or Toxic Industrial Chemical (TIC) impermeable material, such as those used by and being developed by the U.S. Army, for example, for collective protection shelters. The inner liner 114 could be made of material similar to the outer wall 112 material, or alternatively could be a flexible polymer material, such as polyethylene, etc. Either or both of the liners 112 and 114 could be fabric. In addition, the edges of the liners 112 and 114 adjacent to the floor 16 are sealed to the floor 16 by a heat seal also having the above-described solid, liquid and gas impermeability qualities.
In a preferred embodiment, the soft fabric shelter 150 is supported in a facility 160 that is in the form of a frame, such as a tent, or an air beam structure.
Although preferred embodiments of the present invention have been described and illustrated, it will be apparent to those skilled in the art that various modifications may be made without departing from the principles of the invention.
This application claims the benefit of U.S. Provisional Application No. 60/732,843 filed Nov. 2, 2006, assigned to the assignee of this application and incorporated by reference herein.
Number | Date | Country | |
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60732843 | Nov 2005 | US |