KA DUAL ENERGY X-RAY SOURCE FOR CORONARY ANGIOGRAPHY

Information

  • Research Project
  • 3501448
  • ApplicationId
    3501448
  • Core Project Number
    R43HL042176
  • Full Project Number
    1R43HL042176-01
  • Serial Number
    42176
  • FOA Number
  • Sub Project Id
  • Project Start Date
    1/15/1989 - 35 years ago
  • Project End Date
    7/14/1989 - 34 years ago
  • Program Officer Name
  • Budget Start Date
    1/15/1989 - 35 years ago
  • Budget End Date
    7/14/1989 - 34 years ago
  • Fiscal Year
    1989
  • Support Year
    1
  • Suffix
  • Award Notice Date
    1/12/1989 - 35 years ago

KA DUAL ENERGY X-RAY SOURCE FOR CORONARY ANGIOGRAPHY

A characteristic-line X-ray source is proposed for dual energy subtraction imaging of the human coronary arteries. The source is based on the production of the K alpha lines in a rotating metal compound target bombarded by a high energy electron beam. The electron beam is produced in an inexpensive, compact, single resonator RF accelerator. Predicted available X-ray fluences are compatible with imaging of the coronary arteries after an intravenous injection of iodine contrast agent. Thus, this technique has the potential for greatly reducing patient risks in diagnostic and follow-up angiography procedures. Phase I will comprise an experimental investigation of K X-ray yields and spectral purity of the radiation produced from a target bombarded by a low current, high energy e-beam, and computer calculations of signal to noise ratio in the subtraction image for optimization of X-ray spectral characteristics. The study will culminate in the conceptual design of a K alpha X-ray source suitable for clinical use.

IC Name
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
  • Activity
    R43
  • Administering IC
    HL
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    837
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    SSS
  • Study Section Name
  • Organization Name
    SCIENCE RESEARCH LABORATORY, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    SOMERVILLE
  • Organization State
    MA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    02143
  • Organization District
    UNITED STATES