Claims
- 1. A compound of the formula:
- 2. The compound of claim 1 having the formula:
- 3. The compound of claim 1 having the formula,
- 4. The compound of claim 1 having the formula,
- 5. The compound of claim 1 having the formula,
- 6. The compound of claim 1 having the formula,
- 7. A compound of formula,
- 8. A composition comprising a compound according to any of claims 1-7 and a pharmaceutically acceptable carrier.
- 9. A method of treating a kinase mediated disease or disease symptoms in a mammal comprising administration to said mammal of a compound of any of claims 1-7.
- 10. A method of inhibiting kinase activity in a mammal comprising the step of administering to said mammal a compound of any of claims 1-7.
- 11. A method of making a compound of any of claims 1-7 comprising reacting a pyrimidinone of the formula:
- 12. The method of claim 11, wherein R1 is CN; R3 is as defined in any of claims 1-7; X is O; and R5 is Me.
Parent Case Info
[0001] This application is a divisional of U.S. application Ser. No. 09/528,976 filed Mar. 21, 2000, which is a continuation-in-part of U.S. application Ser. No. 09/488,582, filed Jan. 21, 2000, which claims priority to U.S. Provisional Application No. 60/116,697, filed Jan. 22, 1999 all of which are incorporated herein by reference.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60116697 |
Jan 1999 |
US |
Divisions (1)
|
Number |
Date |
Country |
Parent |
09528976 |
Mar 2000 |
US |
Child |
10278369 |
Oct 2002 |
US |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
09488582 |
Jan 2000 |
US |
Child |
09528976 |
Mar 2000 |
US |