Claims
- 1. A kit of parts which comprises:(a) a first container comprising therein a polymerizable cyanoacrylate ester which in monomeric form is represented by the formula: and(b) a second container comprising therein an antimicrobially effective amount of a compatible antimicrobial agent.
- 2. The kit according to claim 1 wherein said antimicrobial agent is selected from the group consisting of PVP-I2, hexachlorophene and tetracycline hydrochloride.
- 3. The kit according to claim 1 which further comprises a biocompatible plasticizer.
- 4. The kit according to claim 1 which further comprises a polymerization inhibitor.
- 5. A kit of parts according to claim 1 further comprising an applicator means for applying the composition onto mammalian skin.
- 6. A kit of parts according to claim 5 wherein one of the containers and applicator means are combined into a single article.
- 7. A kit of parts according to claim 5 herein the containers and applicator means are separate articles.
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a divisional of application No. 09/185,227, now abandoned, filed Nov. 3, 1998 which, in turn, is a continuation-in-part of application No. 08/962,869 filed Nov. 3, 1997 now U.S. Pat. No. 6,090,397.
US Referenced Citations (37)
Foreign Referenced Citations (2)
Number |
Date |
Country |
WO 9325196 |
Dec 1993 |
WO |
WO 9623532 |
Aug 1996 |
WO |
Non-Patent Literature Citations (4)
Entry |
Hagen et al., “A Comparison of Two Skin Preps Used in Cardiac Surgical Procedures,” AORN Journal, 1995, 62(3):393-402. |
Osuna, et al., “Comparison of an Antimicrobial Adhesive Drape and Povidone-Iodine Preoperative Skin Preparation in Dogs,” Veterinary Surgery, 1992, 21(6):458-462. |
Ritter, et al., “Retrospective Evaluation of an Iodophor-Incorporated Antimicrobial Plastic Adhesive Wound Drape,” Clinical Orthopedics and Related Research, 1988, pp. 307-308. |
Blum, et al., In vitro Determination of the Antimicrobial Properties of Two Cyanoacrylate Preparations, J. Dent. Res., 1975, 54(3):500-503. |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
08/962869 |
Nov 1997 |
US |
Child |
09/185227 |
|
US |