Patent Application
20240180157
The present invention provides a launderable bactericidal and virucidal fabric finish, the fabric incorporating thereof, and method of preparing the same.
Textiles that are subject to contact with human skin and bodily fluids are known to be carriers of microorganisms such as viruses and bacteria. Textile fibers and the warmth of the human body are both conducive to microorganism growth. For example, studies demonstrate that coronavirus SARS-CoV-1 and SARS-CoV-2 can reside on cloth for more than one day, and remain active up to one week at 22° C. . Fabric and garment products, rather than acting as a physical barrier between skin and outer environment, can act as a transmission medium for viruses causing severe respiratory tract infections between humans. This is especially problematic during seasonal epidemics or even influenza pandemics.
Commercial antimicrobial fabric treatments are typically used on fabric and garment products to tackle only odor-causing bacteria and fungi. Many of these treatments are available as film forming solutions to provide physical adhesion on fiber or fabric, and yet are not durable against multiple home laundry cycles meeting industry requirements of lifestyle wear and sports apparel. Some of these treatments might change appearance of material by slow oxidation with oxygen or light of the active ingredient. Further, these treatments do not demonstrate virucidal capability.
Antiviral and antibacterial fabrics using silver, typically in the form of silver nanoparticles, are known. However, silver is a costly treatment for fabrics which limits its widespread application. Thus, there is a need for a silver-free fabric treatment. The present invention addresses this need.
Further, there is a need in the art for a launderable bactericidal and virucidal fabric finish that has outstanding activity in the form of viral reduction of viruses causing human respiratory tract infections, in addition to its deodorization capability. The finish must be durable against multiple home laundry cycles in order to meet industry requirements. Further, the finish cannot change of fabric performance such as color fastness and touch sensation.
Accordingly, one aspect of the present invention provides a kit for a silver-free launderable bactericidal and virucidal fabric finish formulation. The first component is a bactericidal and virucidal agent represented by formula (I):
A second kit component includes one or more crosslinkers and/or one or more catalysts.
A third kit component includes one or more transition metal salts.
In an embodiment, the one or more crosslinkers is/are selected from citric acid, tricarballylic acid, 1,2,3,4-butanetetracarboxylic acid, 1,2,4,5-benzenetetracarboxylic acid, cis,cis,cis,cis-1,2,3,4-cyclopentanetetracarboxylic acid, 1,3,5-cyclohexanetricarboxylic acid, 1,2,3,4,5,6-cyclohexanehexacarboxylic acid, and/or ethylenediaminetetraacetic acid.
In an embodiment, the one or more catalysts is/are selected from sodium dihydrogen phosphate, sodium hydrogen phosphate, sodium phosphate, ammonium dihydrogen phosphate, sodium hypophosphite, cyanamide, dicyandiamide, sodium hydrogen cyanamide, disodium cyanamide, and/or sodium hydroxide.
In an embodiment, the one or more transition metal salts include one or more of zinc acetate, zinc acetate dihydrate, zinc gluconate, copper(II) acetate, copper(II) acetate hydrate, and copper(II) gluconate.
In an embodiment, the fabric is coated with the first and/or second part(s) of the formulation at a liquor ratio of 1:4 to 1:40, and wherein the fabric is a cotton fabric.
In an embodiment, the cotton fabric may be a jersey knit, a poplin, or a twill.
Another aspect of the present invention provides a method of preparing a launderable bactericidal and virucidal fabric. A first solution includes the first and second components in a solution. A fabric is dip-coated into the first solution to a fabric at a liquor ratio of 1:4 to 1:40. Following drying a second solution including the one or more transition metal salts is provided. The fabric is dip-coated into the second solution at a liquor ratio of 1:4 to 1:40.
In an embodiment, the liquor ratio is 1:34 to 1:40 for said dip-coating the first solution or second solution to the fabric.
In another embodiment, the liquor ratio is 1:4 to 1:5 for said dip-coating the first solution or second solution to the fabric.
In an embodiment, the fabric is coated such that it has a coating weight of approximately 6.5 to 54.0 g/m2.
The fabric including the launderable bactericidal, fungicidal, virucidal fabric finish that is prepared according to the present invention is capable of reducing bacterial growth and activity from bacteria including but not limited to Staphylococcus aureus, Klebsiella pneumonia and Escherichia coli, and/or is capable of reducing viral growth and activity from viruses including but not limited to H1N1, H3N2, SARS-CoV-2 strains by at least 90%, and/or is capable of deodorizing odorants including acetic acid and isovaleric acid.
Another aspect of the present invention provides a kit for a silver-free launderable bactericidal and virucidal fabric finish formulation. The first component is a bactericidal and virucidal agent represented by formula (I):
A second kit component includes one or more crosslinkers and/or one or more catalysts.
Another aspect of the present invention provides a method of preparing a launderable bactericidal and virucidal fabric. A first solution includes the first and second components in a solution. A fabric is dip-coated into the first solution to a fabric at a liquor ratio of 1:4 to 1:40. The dip-coated fabric is dried and/or cured.
The terms “a” or “an” are used to include one or more than one and the term “or” is used to refer to a nonexclusive “or” unless otherwise indicated. In addition, it is to be understood that the phraseology or terminology employed herein, and not otherwise defined, is for the purpose of description only and not of limitation. Furthermore, all publications, patents, and patent documents referred to in this document are incorporated by reference herein in their entirety, as though individually incorporated by reference. In the event of inconsistent usages between this document and those documents so incorporated by reference, the usage in the incorporated reference should be considered supplementary to that of this document; for irreconcilable inconsistencies, the usage in this document controls.
In the methods of preparation described herein, the steps can be carried out in any order without departing from the principles of the invention, except when a temporal or operational sequence is explicitly recited. Recitation in a claim to the effect that first a step is performed, and then several other steps are subsequently performed, shall be taken to mean that the first step is performed before any of the other steps, but the other steps can be performed in any suitable sequence, unless a sequence is further recited within the other steps. For example, claim elements that recite “Step A, Step B, Step C, Step D, and Step E” shall be construed to mean step A is carried out first, step E is carried out last, and steps B, C, and D can be carried out in any sequence between steps A and E, and that the sequence still falls within the literal scope of the claimed process. A given step or sub-set of steps can also be repeated. Furthermore, specified steps can be carried out concurrently unless explicit claim language recites that they be carried out separately. For example, a claimed step of doing X and a claimed step of doing Y can be conducted simultaneously within a single operation, and the resulting process will fall within the literal scope of the claimed process.
The present invention will be described in detail through the following embodiments/examples with appending drawings. It should be understood that the specific embodiments are provided for an illustrative purpose only, and should not be interpreted in a limiting manner.
The present invention relates to a launderable bactericidal and virucidal fabric finish. The finish is capable of being laundered in a conventional manner. In one aspect, the invention provides a kit for the launderable bactericidal and virucidal fabric finish formulation. Advantageously, the kit may be applied using domestic laundry equipment rather than commercial equipment. To this end, it is noted that the fabric finish using the kits of the present invention may use relatively low curing temperatures, for example, curing temperatures of 60-180° C. As a result, the kits may be directly applied to clothing and other fabrics by consumers, at home, using ordinary laundry machines.
The kit includes a first component with a bactericidal and virucidal agent represented by formula (I):
The kit includes a second component which may be either one or more crosslinker and/or one or more catalysts. The kit may optionally include a third component which may be one or more transition metal salts.
Formula (I) represents a beta-cyclodextrin. The functional groups of formula (II) to (VII) that are substituted jointly or independently on R1, R2, and/or R3 on beta-cyclodextrin creates a substituted beta-cyclodextrin that is specifically engineered to create a compound that enables molecular mimicry of sialic acid on mammalian cells, therefore interacting with the spike glycoproteins on the membrane surface of a virus, and subsequently irreversibly binding onto the oligosaccharides of a virus. The presence of these glycoproteins is crucial for enveloped viruses, including influenza viruses and coronaviruses, for binding onto target host human cells, and induce subsequent viral replication leading to human infection by the virus. The irreversible binding of these spike proteins by the substituted beta-cyclodextrin that includes at least one functional groups of formula (II) to (VII) on positions R1, R2, and R3 thus reduces the ability of these envelope viruses to attach to host human cells.
The one or more crosslinkers may be citric acid, tricarballylic acid, 1,2,3,4-butanetetracarboxylic acid, 1,2,4,5-benzenetetracarboxylic acid, cis, cis, cis, cis-1,2,3,4-cyclopentanetetracarboxylic acid, 1,3,5-cyclohexanetricarboxylic acid, 1,2,3,4,5,6-cyclohexanehexacarboxylic acid, and/or ethylenediaminetetraacetic acid. The crosslinkers serve to bind the bactericidal and virucidal agent represented by formula (I) to the fabric fibers by forming an ester linkage of the hydroxy (OH) groups from the bacterial and virucidal agent with the carboxylic acid groups on the crosslinkers at one end, and the hydroxy group from the anhydroglucose repeating unit of cellulose on fabric with the carboxylic acid groups on the crosslinkers at the other end. This ester-linkage provides durability of the fabric finished, particularly during the course of laundering such that there is no leaching of the bactericidal and virucidal agent.
The one or more catalysts may be sodium dihydrogen phosphate, sodium hydrogen phosphate, sodium phosphate, ammonium dihydrogen phosphate, sodium hypophosphite, cyanamide, dicyandiamide, sodium hydrogen cyanamide, disodium cyanamide, and/or sodium hydroxide. The catalysts facilitate an ester-linkage formation as the bactericidal and virucidal agent represented by formula (I) binds to the fabric fibers. The catalyst activates the carboxylic acid groups of the crosslinkers to form reactive acid anhydrides which subsequently react with the hydroxy groups from the anhydroglucose repeating unit of cellulose on fabric, and the hydroxy groups from those of the bactericidal and virucidal agent.
The transition metal salts may be one or more of zinc acetate, zinc acetate dihydrate, zinc gluconate, copper(II) acetate, copper(II) acetate hydrate, and copper(II) gluconate, and bind to the bactericidal and virucidal agent represented by formula (I) comprising functional groups disclosed in formula (II) to (VII). The bound copper or zinc ions are capable of inducing an oligodynamic effect on incoming bacteria and viruses at low concentrations. For instance, zinc homeostasis is disrupted when zinc ions penetrate into a virus. This impairs viral replication (i.e., virus inactivation) by binding zinc ions to the RNA in the virus. In addition, copper ions work synergistically with zinc ions to impact and enhance virucidal activity against coronavirus. In contrast, unbound metal ions lack such properties, as they are incapable of penetrating the glycoprotein membrane and interacting with the RNA structure of the virus, and therefore showing much lower virucidal capability.
It is noted that the transition metal salts set forth above do not require the presence of silver. That is, the present invention provides a silver-free fabric treatment system; silver is not required to provide the bactericidal and virucidal properties of the treated fabric.
The components of the kit described above may be easily applied to fabric by a dip-coating technique using the components in solution. A first solution is provided that includes the compound of formula (I) and also the crosslinker and/or one or more catalysts. The amount of compound of formula (I) is 2-8% by weight, the amount of crosslinker is 7-10% by weight, and the amount of catalyst is 5-9% by weight. The liquor to fabric ratio is approximately 1:4 to 1:40. An exemplary range is 1:4 to 1:5 in one embodiment and 1:34 to 1:40 in another embodiment.
A fabric is dip-coated in the first solution. The term “dip-coat” as used herein broadly relates to any technique in which a fabric is immersed in a solution with or without mechanical agitation during the dip-coating. As such, a conventional washing machine using a “soak” type of cycle may be used to apply the coating along with commercial machines for applying fabric finishes. Permitting consumers to use domestic laundry equipment at lower cure temperatures of 60-120° C. enables home application. This is important since fabrics that are subject to frequent washing may need repeated application over the lifetime of a garment or other fabric and consumers may wish to re-apply the finish.
The term “liquor ratio” in the specification represents the weight ratio of fabric to the liquid components in first or second solution of the formulation. For example, in Example 2, the liquor ratio (1:34) comes from the weight ratio of fabric to distilled water (25:830).
The term “pad” in the specification represents the removal or squeezing of water from wet fabric with pressure.
A variety of fabrics may use the fabric finish of the present invention. Such fabrics include, but are not limited to polyester-based fabrics, nylon-based fabrics, cotton fabrics, and cotton-blend fabrics. In particular, fabrics that include some cellulose fibers are particularly suited to bind with the cyclodextrin of formula. These include cotton, cotton-polyester blends, cotton-nylon blends, and cotton-spandex blends. Particular cotton-based fabrics include jersey knits, poplins, and twills.
The dip-coating may be performed at room temperature (defined as approximately 20-27° C.) or it may occur at an elevated temperature of 28-80° C. The duration of the dip-coating may range from approximately 5 to 60 minutes depending in part upon the weight and density of the fabric. After drying and/or curing the dip-coated fabric, the fabric is washed with water and then tumble dried the washed fabric for about 30 to 60 minutes at about 60 to 90° C. Drying may be by air-drying or drying at elevated temperature. For elevated temperatures, commercial or household clothes dryers may be used to perform the drying. The drying time will depend upon the weight of the fabric but typically the time is about 5 to 60 minutes at a temperature of about 60 to 180° C.
Following drying, the fabric that has been treated with the first solution is dip-coated in the second solution that includes the metal salt. The dip-coating may be performed at room temperature or it may occur at an elevated temperature of 28-80° C. The duration of the dip-coating may range from approximately 5 to 60 minutes depending in part upon the weight and density of the fabric. After drying and/or curing the dip-coated fabric, the fabric is washed with water and then tumble dried the washed fabric for about 30 to 60 minutes at about 60 to 90° C. Drying may be by air-drying or drying at elevated temperature. For elevated temperatures, commercial or household clothes dryers may be used to perform the drying. The drying time will depend upon the weight of the fabric but typically the time is about 30 to 60 minutes at a temperature of about 60 to 90° C. Optionally, the dip-coating in a metal salt solution may be repeated using a different metal salt solution.
A fabric having the launderable bactericidal and virucidal fabric finish prepared as described above has bactericidal, fungicidal, virucidal activity of at least 90% in terms of reducing bacterial or viral growth and activity from bacteria including one or more of Staphylococcus aureus, Klebsiella pneumonia and Escherichia coli, and viruses including H1N1 and H3N2, SARS-CoV-2 strains, and/or has deodorizing performance of at least 90% including one of more of acetic acid and isovaleric acid. Details of fabric testing against bacteria and viruses are set forth in the Examples, below. The coating weight of the fabric finish ranges from approximately 6.5 to approximately 54.0 g/m2.
Another aspect of the present invention relates to a launderable bactericidal and virucidal fabric finish. The finish is capable of being laundered in a conventional manner. In one aspect, the invention provides a kit for the launderable bactericidal and virucidal fabric finish formulation. The kit includes a first component with a bactericidal and virucidal agent represented by formula (I):
The components of the kit described above may be easily applied to fabric by a dip-coating technique using the components in solution. A first solution is provided that includes the compound of formula (I) and also the crosslinker and/or one or more catalysts. The amount of compound of formula (I) is 2-8% by weight, the amount of crosslinker is 7-10% by weight, and the amount of catalyst is 5-9% by weight. The liquor to fabric ratio is approximately 1:4 to 1:40. An exemplary value is 1:4 in one embodiment.
A variety of fabrics may use above fabric finish. Such fabrics include, but are not limited to polyester-based fabrics, nylon-based fabrics, cotton fabrics, and cotton-blend fabrics. In particular, fabrics that include some cellulose fibers are particularly suited to bind with the cyclodextrin of formula. These include cotton, cotton-polyester blends, cotton-nylon blends, and cotton-spandex blends. Particular cotton-based fabrics include jersey knits, poplins, and twills.
The dip-coating may be performed at room temperature (defined as approximately 20-27° C.) or it may occur at an elevated temperature of 28-80° C. The duration of the dip-coating may range from approximately 5 to 60 minutes depending in part upon the weight and density of the fabric. After drying and/or curing the dip-coated fabric, the fabric is washed with water and then tumble dried the washed fabric for about 30 to 60 minutes at about 60 to 90° C. Drying may be by air-drying or drying at elevated temperature. For elevated temperatures, commercial or household clothes dryers may be used to perform the drying. The drying time will depend upon the weight of the fabric but typically the time is about 5 to 60 minutes at a temperature of about 60 to 180° C.
Table 1 below provides an overview of the first solution of the general formulation for dip-coating a fabric in order to form a launderable bactericidal and virucidal fabric finish in the fabric.
1. The components in Table 1 were dissolved in distilled water at 25° C. to form the first solution.
2. A piece of cotton fabric was dip-coated using the first solution for about 5 to 60 minutes at about 25 to 80° C. at a liquor ratio of 1:4 to 1:40.
3. The wet fabric was padded and dried at 60 to 180° C. for 5 to 60 minutes.
4. The dried fabric was rinsed with water, padded, and tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 2 to form a second solution of the formulation.
6. The dried cotton fabric from step 4 was further dip-coated with the second solution for about 5 to 60 minutes at about 25° C.
7. The wet fabric was padded and dried at 60 to 180° C. for 5 to 60 minutes.
8. The fabric was rinsed with water, padded, followed by drying at about 60 to 90° C. for about 30 to 60 minutes.
The general coating weighed from 6.5 to 54.0 g/m2 upon applying the finish to fabric after drying.
Table 3 provides a first solution of the formulation 1 for dip-coating cotton fabric including jersey knit
1. The components of Table 3 were dissolved in distilled water at about 25° C. to form the first solution.
2. Cotton fabric was dip-coated with the first solution at a liquor ratio of 1:34 for about 5 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 60 minutes, followed by curing at about 180° C. for about 5 minutes.
4. The dried fabric was rinsed with water, padded, and tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 4 to form a second solution.
6. The dried cotton fabric from step 4 was further dip-coated with the second solution for about 5 to 60 minutes at about 25° C.
7. The wet fabric was padded and dried at about 80° C. for about 60 minutes.
8. The dried fabric was rinsed with water, padded, and tumble dried to remove absorbed water.
The coating weighed from approximately 23.6 to 54.0 g/m2 upon applying the finish to fabric after drying.
Table 5 provides a first solution of the formulation 1 for dip-coating cotton fabric including jersey knit, poplin, and twill.
1. The components of Table 5 were dissolved in distilled water at about 25° C. to form the first solution.
2. Cotton fabric was dip-coated with the first solution at a liquor ratio of 1:34 for about 5 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 60 minutes, followed by curing at about 180° C. for about 5 minutes.
4. The dried fabric was rinsed with water, padded, and tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 6 to form a second solution of the formulation.
6. The cotton fabric from step 4 was further dip-coated with the second solution at a liquor ratio of 1:38 for about 5 minutes.
7. The wet fabric was padded and dried at about 80° C. for about 60 minutes.
8. The dried fabric was rinsed with water, padded, and tumble dried to remove absorbed water.
The coating weighed from approximately 8.1 to 54.0 g/m2 upon applying the finish to fabric after drying.
Table 7 below provides a first solution of the formulation 2 for dip-coating a cotton fabric of jersey knit.
1. The components of Table 7 were dissolved in distilled water at about 25° C.
2. Cotton fabric of jersey knit was dip-coated with the first solution at a liquor ratio of 1:4 for about 5 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
4. The dried fabric was rinsed with water, padded, and then tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 8 to form a second solution of the formulation.
6. The cotton fabric from step 4 was further dip-coated with the second solution at a liquor ratio of 1:6 for about 5 minutes.
7. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
8. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 6.5 to 17.0 g/m2 upon applying the finish to fabric after drying.
Table 9 below provides a first solution of the formulation 3 for dip-coating a cotton fabric of jersey knit.
1. The components of Table 9 were dissolved in distilled water at about 25° C.
2. Cotton fabric of jersey knit was dip-coated with the first solution at a liquor ratio of 1:4 for about 5 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 60 minutes.
4. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 10 to form a second solution.
6. The cotton fabric from step 4 was further dip-coated with the second solution at a liquor ratio of 1:5 for about 5 minutes.
7. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
8. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 7.0 to 16.8 g/m2 upon applying the finish to fabric after drying.
Table 11 below provides a first solution of the formulation 4 for dip-coating a cotton fabric of jersey knit.
1. The components of Table 11 were dissolved in distilled water at about 25° C.
2. Cotton fabric of jersey knit was dip-coated with the first solution at a liquor ratio of 1:4 for about 30 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 60 minutes.
4. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 12 to form a second solution.
6. The cotton fabric from step 4 was further dip-coated with the second solution at a liquor ratio of 1:6 for about 30 minutes.
7. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
8. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 11.6 to 16.3 g/m2 upon applying the finish to fabric after drying.
9. Alternatively, copper acetate monohydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 13 to form a second solution.
10. The cotton fabric from example 6, step 4 was further dip-coated with the second solution at a liquor ratio of 1:6 for about 30 minutes.
11. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
12. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
13. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 14 to form a third solution.
14. The cotton fabric from step 12 was further dip-coated with the third solution at a liquor ratio of 1:5 for about 30 minutes.
15. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
16. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 14.0 to 15.9 g/m2 upon applying the finish to fabric after drying.
Table 15 below provides a first solution of the formulation 6 for dip-coating of cotton-blended fabric comprising 5% spandex and 95% cotton, and/or fabric comprising 30% polyester and 70% cotton.
1. The components of Table 15 were dissolved in distilled water at about 25° C.
2. Cotton-blended fabrics including fabric comprising 5% spandex and 95% cotton, and/or fabric comprising 30% polyester and 70% cotton was dip-coated with the first solution at a liquor ratio of 1:5 for about 30 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 60 minutes.
4. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 16 to form a second solution of the formulation.
6. The cotton-blended fabric from step 4 was further dip-coated with the second solution at a liquor ratio of 1:5 for about 30 minutes.
7. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
8. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 15.5 to 22.2 g/m2 upon applying the finish to fabric after drying.
9. Alternatively, copper acetate monohydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 17 to form a second solution.
10. The cotton-blended fabric from example 7, step 4 was further dip-coated with the second solution at a liquor ratio of 1:5 for about 30 minutes.
11. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
12. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
13. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 18 to form a third solution of the formulation.
14. The cotton-blended fabric from step 12 was further dip-coated with the third solution at a liquor ratio of 1:5 for about 30 minutes.
15. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
16. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 25.6 to 27.4 g/m2 upon applying the finish to fabric after drying.
Table 19 below provides a first solution of the formulation 8 for dip-coating a cotton fabric of jersey knit.
11-12.5
1. The components of Table 19 were dissolved in distilled water at about 25° C.
2. Cotton fabric of jersey knit be dip-coated with the first solution at a liquor ratio of 1:4 for about 30 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 60 minutes.
4. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 13.6 to 18.8 g/m2 upon applying the finish to fabric after drying.
5. Alternatively, zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 20 to form a second solution.
6. The cotton fabric from example 8, step 4 was further dip-coated with the second solution at a liquor ratio of 1:5 for about 30 minutes.
7. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
8. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 11.6 to 14.2 g/m2 upon applying the finish to fabric after drying.
Table 21 below provides a first solution of the formulation 10 for dip-coating a cotton-polyester blended fabric comprising 30% polyester and 70% cotton.
1. The components of Table 21 were dissolved in distilled water at about 25° C.
2. Cotton-polyester blended fabric comprising 30% polyester and 70% cotton was dip-coated with the first solution at a liquor ratio of 1:4 for about 30 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 60 minutes.
4. The dried fabric was rinsed with water, padded, and then tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 22 to form a second solution of the formulation.
6. The cotton-polyester blended fabric from step 4 was further dip-coated with the second solution at a liquor ratio of 1:5 for about 30 minutes.
7. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
8. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 15.9 to 19.0 g/m2 upon applying the finish to fabric after drying.
Table 23 below provides a first solution of the formulation 11 for dip-coating a cotton-polyester blended fabric comprising 30% polyester and 70% cotton.
1. The components of Table 23 were dissolved in distilled water at about 25° C.
2. Cotton-polyester blended fabric comprising 30% polyester and 70% cotton was dip-coated with the first solution at a liquor ratio of 1:4 for about 30 minutes at about 25° C.
3. The wet fabric was padded and dried at about 80° C. for about 60 minutes.
4. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
5. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 24 to form a second solution.
6. The cotton-polyester-blended fabric from step 4 was further dip-coated with the second solution at a liquor ratio of 1:5 for about 30 minutes.
7. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
8. The dried fabric was rinsed with water, padded and then tumble dried to remove absorbed water.
The coating weighed from approximately 9.1 to 10.2 g/m2 upon applying the finish to fabric after drying.
Table 24 below provides a first solution of the formulation 12 for dip-coating a wool fabric of rib stitch knit.
1. The components of Table 24 except hydrochloric acid (37% w/w aqueous solution) were dissolved in distilled water at about 25° C.
2. The solution was cooled to 0° C., and hydrochloric acid (37% w/w aqueous solution) was added until pH=3.2-3.4. Then the solution was warmed to room temperature.
3. Wool fabric was pre-conditioned at 25° C. and 95% relative humidity in a climatic chamber for at least 4 hours.
4. Wool fabric from step 3 was dip-coated with the first solution at a liquor ratio of 1:6 for about 30 minutes at about 25° C.
5. The wet fabric was padded and dried at about 130° C. for about 30 minutes.
6. The dried fabric was rinsed with water, and then tumble dried to remove absorbed water.
The coating weighed from approximately 7.2 to 165.0 g/m2 upon applying the finish to fabric after drying.
Table 26 below provides a first solution of the formulation 13 for dip-coating a wool fabric of rib stitch knit.
1. The components of Table 25 except hydrochloric acid (37% w/w aqueous solution) were dissolved in distilled water at about 25° C.
2. The solution was cooled to 0° C., and hydrochloric acid (37% w/w aqueous solution) was added until pH=3.2-3.4. Then the solution was warmed to room temperature.
3. Wool fabric was pre-conditioned at 25° C. and 95% relative humidity in a climatic chamber for at least 4 hours.
4. Wool fabric from step 3 was dip-coated with the first solution at a liquor ratio of 1:5 for about 30 minutes at about 25° C.
5. The wet fabric was padded and dried at about 130° C. for about 30 minutes.
6. Zinc acetate dihydrate as a transition metal salt was dissolved in distilled water according to the amount listed in the following Table 26 to form a second solution.
7. The wool fabric from step 5 was further dip-coated with the second solution at a liquor ratio of 1:7 for about 30 minutes.
8. The wet fabric was padded and dried at about 80° C. for about 30 minutes.
9. The dried fabric was rinsed with water, and then tumble dried to remove absorbed water.
The coating weighed from approximately 61.9 to 90.7 g/m2 upon applying the finish to fabric after drying.
The tables below summarize the bactericidal and virucidal activities of Example 2 (Table 28), Example 3 (Table 29), Example 4 (Table 30), Example 5 (Table 31), Example 6 and Alternative Example 6 (Table 32), Example 7 and Alternative Example 7 (Table 33), Example 8 and Alternative Example 8 (Table 34), Example 9 (Table 35), Example 10 (Table 36), Example 11 (Table 39) and Example 12 (Table 40).
Table 37 below summarizes the deodorizing performance of Example 7.
Table 38 below summarizes discoloration grades using grey scale grading against the original finish of cotton-based fabric upon treatment with the present invention.
Staphylococcus
aureus
Klebsiella
pneumonia
Aspergillus
Niger
Staphylococcus
aureus
Klebsiella
pneumonia
Aspergillus
Niger
Aspergillus
Niger
Aspergillus
Niger
Aspergillus
Niger
Staphylococcus
aureus
Klebsiella
pneumonia
Substitution of Groups Group (II), (III), (IV), (V), (VI) or (VII) at R1, R2 and/or R3
The present invention is applicable in textile and garments which require antibacterial and antiviral functions with durability and launderability. The finishes may be applied to fabric prior to fabrication into clothing or other uses; alternatively, they may be applied to finished articles of clothing, medical apparel, surgical masks, wound dressings, etc. Alternatively, the kits of the present invention may be sold to consumers for home application to clothing or fabrics.
The present application is a continuation-in-part of U.S. patent application Ser. No. 17/692,193, filed Mar. 11, 2022, which claims priority to U.S. Provisional Patent Application 63/159,477, filed 11 Mar. 2021, the disclosures of which are incorporated by reference herein.
| Number | Date | Country | |
|---|---|---|---|
| 63159477 | Mar 2021 | US |
| Number | Date | Country | |
|---|---|---|---|
| Parent | 17692193 | Mar 2022 | US |
| Child | 18509310 | US |
