LEADERSHIP, PLANNING AND EVALUATION ? PROJECT SUMMARY/ABSTRACT The Cold Spring Harbor Laboratory (CSHL) Cancer Center is led by Director David Tuveson (Cellular Communication in Cancer Program). Tuveson succeeded former Cancer Center Director Bruce Stillman as the Director of the Cancer Center in 2016. As Director, Tuveson is responsible for the overall direction, planning, and allocation of Cancer Center Developmental and discretionary funds to support his vision for the CSHL Cancer Center, including support of cancer research and the Shared Resources. He is assisted by four Deputy Directors: Adrian Krainer (Gene Regulation and Inheritance Program), Nicholas Tonks (Cellular Communication in Cancer Program), Lloyd Trotman (Cellular Communication in Cancer Program), and Denise Roberts (Administration). Krainer, Deputy Director of Programs, is primarily responsible for oversight of Cancer Center Programs to ensure they align with the strategic vision for the Cancer Center, and for determining the cancer relevance of members? grants. Tonks, Deputy Director of Operations, is primarily responsible for oversight of the Shared Resources to ensure they maintain exceptional services and scientific support. Trotman, Deputy Director of Education and Diversity, oversees Cancer Center educational initiatives, advises in Cancer Center recruitment, and coordinates Cancer Center educational initiatives with those of the T32 Cancer Training Grant. Roberts, Deputy Director of Administration, coordinates all administrative services on behalf of the Cancer Center and aids Tonks in the management of Shared Resources. Tuveson has instituted several changes to the CSHL Cancer Center, including the appointment of new Leadership, reorganization and rebranding of Cancer Center Programs, recruitment of new members, establishing new Share Resources, launching of new educational initiatives, and strengthening the alliance between the Cancer Center and Northwell Health to promote translational research. Planning and evaluation are critical to ensure the Cancer Center maintains its highly innovative research and first-rate Shared Resources. With the help of Cancer Center Senior Leadership and the Cancer Center Executive Committee, the Director has developed a clear, yet flexible, vision for the coming grant cycle. Advice from both internal and external committees, including the External Advisory Board, is used by the Cancer Center Leadership to evaluate plans and ensure that strategic initiatives are well designed and effectively implemented. The CSHL Cancer Center Leadership are committed to maintaining and continually improving the Cancer Center to ensure its position as a premiere institute for basic cancer research.