Patent Application
20240091289
The present disclosure relates to a lichen extract-based formulation; feed pellet, protein block and solution containing the base formulation; lichen extract-based spray cleaner and methods for administration of the formulations to cervids.
Chronic wasting disease (CWD) is a prion-related disease that effects cervids, such as deer, elk, reindeer, sika deer, and moose. CWD is problematic as more animals come into contact with infectious prions, by direct contact with an infected cervid or viable CWD prions in the environment. Transmission among cervids is enhanced by activities that promote the congregation of animals, such as baiting or feeding. As more cervids become infected, the subsequent environmental contamination multiplies, playing a key role in the continued spread of CWD.
Prior research (Prion Research Laboratory, 2002) has suggested that some lichens (extracts from Lobaria pulmonaria and Cladonia rangiferina) on the landscape could have potential to break down the infectious prions that are responsible for causing chronic wasting disease. Lichens produce unique organic compounds that have antibiotic and antiviral properties.
In accordance with one aspect of the present disclosure, there is provided a cervid base formulation including a mixture of reindeer lichen extract (Cladonia rangiferina), lung lichen extract (Lobaria pulmonaria), and witch's hair lichen extract (Alectoria sarmentosa).
In accordance with another aspect of the present disclosure, there is provided a formulation containing a lichen extract mixture; protein; fat; fiber; vitamins; minerals; a preservative and an emulsifier, in the form of a protein block, wherein the mixture contains from 1% to 40% by weight reindeer lichen extract (Cladonia rangiferina), from 1% to 40% by weight lung lichen extract (Lobaria pulmonaria), and from 5% to 45% by weight witch's hair lichen extract (Alectoria sarmentosa).
In accordance with another aspect of the present disclosure, there is provided a formulation containing a lichen extract mixture; protein; fat; fiber; vitamins; minerals; a preservative and an emulsifier, in the form of a feed supplement, wherein the mixture comprises from 1% to 40% by weight reindeer lichen extract (Cladonia rangiferina), from 1% to 40% by weight lung lichen extract (Lobaria pulmonaria), and from 5% to 45% by weight witch's hair lichen extract (Alectoria sarmentosa).
In accordance with another aspect of the present disclosure, there is provided a lichen extract-based spray cleaner formulation, including: an ingredient of at least one of reindeer lichen extract (Cladonia rangiferina) and lung lichen extract (Lobaria pulmonaria); an enzyme stabilizer; preservative; antimicrobial active; and a carrier solvent.
In accordance with another aspect of the present disclosure, there is provided a method, including administering to cervids a composition comprising a mixture of reindeer lichen extract (Cladonia rangiferina), lung lichen extract (Lobaria pulmonaria), and witch's hair lichen extract (Alectoria sarmentosa).
These and other aspects of the present disclosure will become apparent upon a review of the following detailed description and the claims appended thereto.
The present disclosure relates to various formulations and methods for administration to cervids. The cervid base formulation is an additive for use in pelleted feeds, protein blocks, drinking water and in a spray cleaner for use on cervid's and certain livestock facilities. The cervid base formulation is a combination of 3 plant extracts. The cervid base formulation includes extracts of Reindeer Lichen (Cladonia rangiferina), Lung Lichen (Lobaria pulmonaria) and Witch's Hair Lichen (Alectoria sarmentosa). Formulations containing the Witch's Hair Lichen (Alectoria sarmentosa) extract are 75% more digestible than formulations without this extract.
The whole plants are harvested and processed into a powder form through high-temperature sterilization. They appear as a fine brown yellow powder with a moderate odor and a moderate taste. The powder is tested for heavy metals and conforms to standards. The powder undergoes microbial tests and conforms to standards.
Through the process of high-temperature sterilization the whole plants are extracted in extract ratios of 10:1, 20:1, 30:1 and 40:1. Exact extract ratios are used for specific product formulation.
The Reindeer Lichen Extract (Cladonia rangiferina) is used at a percentage range of from 1% to 40% by weight as an additive to the specific product being manufactured.
The Lung Lichen Extract (Lobaria pulmonaria) is used at a percentage range of from 1% to 40% by weight as an additive to specific product being manufactured.
Witch's Hair Lichen Extract (Alectoria sarmentosa) are used at a percentage range of 5% to 45% by weight as an additive to specific product being manufactured.
Preferred base formulations contain extract ratios averaging 10:1, with a base percentage of each product used at an average of 15%.
In an embodiment, the base formulation contains certain preservatives and emulsifiers in the manufacturing process for stability. The base formulation further contains certain minerals used as carriers in the system of the animal. Suitable additives include plant protein products, grain products, monocalcium phosphate, molasses products, calcium carbonate, dicalcium phosphate, salt, manganous oxide, ferrous sulfate, iron oxide, zinc oxide, copper sulfate, cobalt carbonate, ethylendiamine duhyriodide, vitamin A supplement, vitamin D3 supplement, natural and artificial colors, vegetable oil, sodium selenite, processed grain by-products, maganesium-mica, potassium chloride, calcium iodate, vitamin E supplement, zinc sulfate, manganese sulfate, mineral oil, cobalt carbonate, diatomaceous earth, dried seaweed meal, chickory root, cloves, saccharin sodium, hemicellulose extract, origanum oil, lemongrass oil, processed grain by products, forage products, Saccharomyces cerevisae, dried Bacillus licheniformis extract, vitamin E supplement, vitamin B12 supplement, d-biotin, riboflavin supplement, d-calcium pantothenate, menadione sodium bisulfate complex, folic acid, thiamine mononitrate, choline chloride, zinc amino acid complex, manganese amino acid complex, copper amino acid complex, cobalt sulfate, cobalt glucoheptonate, lichen extracts and artificial flavors.
The cervid feed supplement is a pelleted cervid feed product containing the base formulation, which is a mixture of reindeer lichen extract (Cladonia rangiferina), lung lichen extract (Lobaria pulmonaria), and witch's hair lichen extract (Alectoria sarmentosa). In an embodiment, the feed supplement contains protein; fat; fiber; vitamins; minerals; a preservative and an emulsifier, in the form of a feed supplement, wherein the mixture contains from 1% to 40% by weight reindeer lichen extract (Cladonia rangiferina), from 1% to 40% by weight lung lichen extract (Lobaria pulmonaria), and from 5% to 45% by weight witch's hair lichen extract (Alectoria sarmentosa).
The cervid protein block product contains the base formulation, which is a mixture of reindeer lichen extract (Cladonia rangiferina), lung lichen extract (Lobaria pulmonaria), and witch's hair lichen extract (Alectoria sarmentosa). In an embodiment, the protein block contains protein; fat; fiber; vitamins; minerals; a preservative and an emulsifier, in the form of a protein block, wherein the mixture contains from 1% to 40% by weight reindeer lichen extract (Cladonia rangiferina), from 1% to 40% by weight lung lichen extract (Lobaria pulmonaria), and from 5% to 45% by weight witch's hair lichen extract (Alectoria sarmentosa).
The cervid water solution contains the base formulation, which is a mixture of reindeer lichen extract (Cladonia rangiferina), lung lichen extract (Lobaria pulmonaria), and witch's hair lichen extract (Alectoria sarmentosa). 100% of the base formulation can be mixed with water and the solution can be added to the water source of cervids.
The spray product is used as a spray cleaner in livestock facilities to include feed troughs, water tubs, and the like. This spray cleaner product contains a lichen extract. Preferably, the lichen extract is present in an amount of from 5% to 40%. A suitable lichen extract contains reindeer lichen extract (Cladonia rangiferina), lung lichen extract (Lobaria pulmonaria) or a mixture thereof, or the base formulation, which is a mixture of reindeer lichen extract (Cladonia rangiferina), lung lichen extract (Lobaria pulmonaria), and witch's hair lichen extract (Alectoria sarmentosa.
The disclosure will be further illustrated with reference to the following specific examples. It is understood that these examples are given by way of illustration and are not meant to limit the disclosure or the claims to follow.
This example sets forth a formulation in the form of a protein block shown in
Plant protein products, grain products, monocalcium phosphate, molasses products, calcium carbonate, dicalcium phosphate, salt, manganous oxide, ferrous sulfate, iron oxide, zinc oxide, copper sulfate, cobalt carbonate, ethylendiamine duhyriodide, vitamin A supplement, vitamin D3 supplement, natural and artificial colors, vegetable oil, sodium selenite, processed grain by-products, maganesium-mica, potassium chloride, calcium iodate, vitamin E supplement, zinc sulfate, manganese sulfate, mineral oil, cobalt carbonate, diatomaceous earth, dried seaweed meal, chickory root, cloves, saccharin sodium, hemicellulose extract, origanum oil, lemongrass oil, lichen extracts.
This example sets forth a formulation for a feed supplement shown in
Processed grain by products, forage products, plant protein products, can molasses, dicalcium phosphate, monocalcium phosphate, calcium carbonate, salt, Saccharomyces cerevisae, dried Bacillus licheniformis extract, vitamin A supplement, vitamin D3 supplement, vitamin E supplement, vitamin B12 supplement, d-biotin, riboflavin supplement, d-calcium pantothenate, menadione sodium bisulfate complex, folic acid, thiamine mononitrate, choline chloride, zinc sulfate, zinc amino acid complex, manganese sulfate, manganese amino acid complex, copper sulfate, copper amino acid complex, ethylenediamine dihydriodide, cobalt sulfate, cobalt glucoheptonate, sodium selenite, lichen extracts and artificial flavors.
This example tests the stability of various spray cleaner formulations.
Lichen extract-based spray cleaners were made based on the formulations below. All formulations other than the 5% Lung formulation were found to have preferred stability. The good samples demonstrated no visual difference, odor difference, or change in the ability to be sprayed after the aging process.
Reindeer and Lung lichen extract spray cleaners were made with 5, 10, 15, and 20% lichen extract and glycerol in accordance with Table 2. Each was made to 300 g batches. Each spray formulation was placed in its own 32-ounce spray bottle. The spray bottles were labelled and were checked to test the ability of the formulation to be sprayed onto a surface.
Approximately 20 mL of each formulation was retained before spray bottles were placed in stability chamber. After 7 days ˜20 mL of each formulation was collected for visual comparison to samples collected before stability testing. Each bottle was sprayed again to ensure the samples still sprayed easily.
Although various embodiments have been depicted and described in detail herein, it will be apparent to those skilled in the relevant art that various modifications, additions, substitutions, and the like can be made without departing from the spirit of the disclosure and these are therefore considered to be within the scope of the disclosure as defined in the claims which follow.
This application claims the benefit of the filing date of U.S. Provisional Patent Application Ser. No. 63/056,793, filed Jul. 27, 2020, which is hereby incorporated by reference in its entirety.
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/US21/70996 | 7/27/2021 | WO |
| Number | Date | Country | |
|---|---|---|---|
| 63056793 | Jul 2020 | US |
