Worldwide about millions of platelets are donated yearly. Before donated platelets can be used, a sample of the donation is screened for bacteria. To accomplish this, culture bottles of platelets are loaded into a laboratory instrument that performs microbial detection. Culture bottles that test positive for bacteria are sent to an independent laboratory for identification and the corresponding donated platelets are discarded.
Oftentimes, the laboratory instruments that perform the cultures are not interoperable with external monitoring systems. To indicate a sample has tested positive for bacteria, the laboratory instrument includes indicator lights that are viewable by operators within close proximity of the instrument. Detection of bacteria causes the laboratory instrument to activate a light, which provides a visible cue to the operator that the system needs attention. Given the required duration of platelet incubation, instruments are in operation twenty-four hours a day and seven days a week, which means that at least one operator has to be present and in close proximity to the instrument to monitor when an indicator light is activated.
The present disclosure provides a new and innovative system, method, and apparatus for detecting when a light from a laboratory instrument is activated. The system, method, and apparatus are configured to use a photosensor to detect when the light is illuminated. An output from the photosensor is configured to cause a change in a relay switch, which sends a signal to a processor of a system monitor, which may be communicatively coupled to a network. After receiving a signal, the processor is configured to cause the system monitor to generate an alert or alarm indicative that at least one platelet sample has tested positive for bacteria. The system monitor may display the alert or alarm via a user interface and/or may transmit one or more messages to client devices indicative of the light illumination. The disclosed system, method, and apparatus accordingly overcome the lack of interoperability of certain blood analyzer laboratory instruments by using a photosensor that is coupled to a system monitor to bridge the communication gap and allow instruments to be monitored in another location of a building or remotely.
The example system, method, and apparatus also include hardware that compensates for flashing amber or orange lights from the laboratory instrument indictor light. In some embodiments, at least two photoresistors are connected in parallel for detecting amber or orange lights illuminated by one or more indicator lights. Activation of the photoresistors in response to detecting light causes the disclosed hardware to change the state of a relay, which generates the alert or alarm signal discussed above. The photoresistors are electrically coupled to one or more capacitors and one or more transistors. The configuration of the capacitor(s) and transistor(s) in addition to resistors and diodes provides a smoothing or compensation function that keeps the relay in the changed position even when the indicator light is blinking (or temporarily off). Such a configuration prevents the transmission of periodic alert or alarm signals, which may cause multiple alerts or alarms to be generated for each instance of an alert or alarm signal. Alternatively, the periodical transmission of alert or alarm signals might be filtered or disregarded by the processor of the monitoring system. The compensation for indicator light flashing accordingly ensures a single alert or alarm is generated when a laboratory instrument detects bacteria in a platelet sample.
In light of the disclosure set forth herein, and without limiting the disclosure in any way, in a first aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein a photosensor apparatus includes a voltage source and a relay including a coil having an input end and an output end, and a switch connected to the voltage source or a separate voltage source and configured to switch between an open state and a closed state. The photosensor apparatus also includes at least one photoresistor or multiple photoresistors connected in parallel with each other, an input lead of each photoresistor being connected to the voltage source. The photosensor apparatus further includes a first transistor including a first collector or a first source connected to output leads of the photoresistors, a first base or a first gate connected to a first resistor, which is connected to the output leads of the photoresistors, and a first emitter or a first drain that is connected to a second resistor and a third resistor, and a second transistor including a second collector or a second source connected to the output end of the relay coil, a second base or a second gate connected to the second resistor, and a second emitter or a second drain that is connected to a ground. Additionally, the photosensor apparatus includes a capacitor comprising a first end connected to the output leads of the photoresistors and a second end connected to the ground or a different ground. The photoresistors are configured to detect constant or flashing light from an indicator lamp of a laboratory instrument and the combination of the first transistor, the second transistor, and the capacitor are configured to cause the switch of the relay to stay in the closed state when the constant or flashing light is detected.
In a second aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein, the relay is configured to output an alert signal in the closed state. The output signal is transmitted to a processor of a monitoring system, causing the processor to display an alert or an alarm to an operator.
In a third aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein, the photosensor apparatus further includes a circuit board including a power connector that is electrically connected to the voltage source, the relay, the first transistor, the second transistor, and the capacitor, a first wire connected to the power connector via the circuit board and to the input lead(s) of the photoresistor(s), and a second wire connected to a node at the circuit board and respectively to the output lead(s) of the photoresistor(s). The node at the circuit board is connected to the first collector or the first source of the first transistor and the first resistor.
In a fourth aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein, the photosensor apparatus further includes a light control tube configured to enclose at least portions of the first wire, at least portions of the second wire, and the photoresistor(s). The light control tube has an open end configured to be placed adjacent to the indicator light of the laboratory instrument for receiving the flashing or constant light.
In a fifth aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein, an opposite end of the second resistor is connected to an anode of a light emitting diode, and a cathode of the light emitting diode is connected to the ground or a separate ground.
In a sixth aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein, a first diode is connected between the voltage source and the at least one photoresistor or multiple photoresistors, and an anode of a second diode is connected to the second collector or the second source of the second transistor and a cathode of the second diode is connected to the input end of the relay.
In a seventh aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein, the capacitor is a polarized capacitor.
In an eighth aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein, the voltage source is between 5 volts and 12 volts and the capacitor has a value of 1 k uF.
In a ninth aspect of the present disclosure, which may be combined with any other aspect, or portion thereof, described herein, the first and second transistors are bipolar junction transistors (“BJTs”) or metal-oxide-semiconductor field-effect transistor (“MOSFETs”).
In accordance with an aspect of the present disclosure, any of the structure and functionality illustrated and described in connection with
In light of the aspects above and the disclosure herein, it is accordingly an advantage of the present disclosure to provide a system that bridges a communication gap between a laboratory instrument by detecting an illumination state of an indicator light and alarm/alert monitoring system.
It is another advantage of the present disclosure to provide remote indications of an alert or alarm from a laboratory instrument using a photosensor apparatus.
It is a further advantage of the present disclosure to provide remote monitoring of donated platelets undergoing testing by a laboratory instrument for possible bacteria.
Additional features and advantages are described in, and will be apparent from, the following Detailed Description and the Figures. The features and advantages described herein are not all-inclusive and, in particular, many additional features and advantages will be apparent to one of ordinary skill in the art in view of the figures and description. Also, any particular embodiment does not have to have all of the advantages listed herein and it is expressly contemplated to claim individual advantageous embodiments separately. Moreover, it should be noted that the language used in the specification has been selected principally for readability and instructional purposes, and not to limit the scope of the inventive subject matter.
The present disclosure relates in general to a method, apparatus, and system for detecting light for alerting or alarming an external monitoring system. Light from an indicator lamp is detected using a plurality of photoresistors connected in parallel with each other. Light detection causes a resistance of the photoresistors to decrease, thereby enabling current to flow through a monitoring circuit. A relay (or switch) of the monitoring circuit is configured to switch or actuate from an open state to a closed state (or vice versa) when the photoresistors detect light. The monitoring circuit includes transistors and one or more capacitors that are configured to filter or smooth a voltage across the relay, enabling the relay to stay in the changed state even when the detected light is blinking or flickering. The relay outputs an alert or alarm signal in the changed state. The alarm signal is used to indicate to a separate monitoring system that the indicator light is illuminated. The method, apparatus, and system accordingly provide a constant alert or alarm signal despite any fluctuations with the illuminated light.
The method, apparatus, and system are configured to bridge a communication gap between a laboratory analyzer and a monitoring system. In some instances, a laboratory analyzer may not be configured for interoperability with separate monitoring systems. For instance, a laboratory instrument may be configured in a first protocol while a monitoring system is configured with a second, different protocol that prevents the laboratory instrument from communicating with the monitoring system via a network or serial connection.
The method, apparatus, and system bridge the communication gap by taking advantage of a light output of the laboratory instrument. Oftentimes, known laboratory instruments include a status light (e.g. a green light, an orange/amber light, and a red light). The laboratory instrument is configured to switch from a green light to an orange/amber or red light when an alert or alarm is generated, such as when a platelet sample tests positive for bacteria. The method, apparatus, and system are configured to detect the illumination of the orange/amber light and/or the red light and output a corresponding alert or alarm signal to the monitoring system. The method, apparatus, and system accordingly enable a laboratory instrument to be monitored remotely even when a communication connection with a monitoring system is not possible.
Reference is made throughout to laboratory instruments and detecting a light status of such instruments. The laboratory instrument may be located in settings including but not limited to a blood donation processing center or a medical center. It should be appreciated that the method, apparatus, and system may be applied to any device that has a status or indicator light, such as power systems, process control systems, industrial systems, manufacturing systems, queue systems, first responder systems, military systems, and/or residential security systems.
The laboratory instrument 102 includes a sample analysis receptacle 104 that is configured to receive one or more containers, cuvettes, or vials of a fluid sample, such as a platelet sample. The laboratory instrument 102 includes components for analyzing the containers from the sample analysis receptacle 104. The components may include pipettes for adding one or more reagents, incubation devices, a centrifuge for sample separation/concentration, and camera/sensors for measuring sample reactions with reagents.
A processor 106 of the laboratory instrument 102 is configured to analyze samples placed in the sample analysis receptacle 104 for one or more analytes. In the illustrated example, the laboratory instrument 102 analyzes platelet samples for the presence of certain bacteria. In other embodiments, the laboratory instrument 102 may analyze a blood sample (or urine sample) for the presence of one of more chemicals, drugs, biologics, etc.
The laboratory instrument 102 also includes an indicator status lamp 108.
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As shown in
The photoresistor(s) 114 are located inside of the light control tube 112. In some embodiments, the photoresistor(s) 114 are placed between one to four inches within the light control tube 112 from an open end 304 to prevent ambient light from being detected. The configuration shown in
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The example relay 406 (or switch) of the light sensing circuit 115 includes a coil 408 and a switch 410. An input end of the coil 408 is electrically connected to the cathode of the diode 404. The switch 410 of the relay 406 may be electrically connected to the cathode of the diode 404 or may be connected to a separate circuit. The switch 410 is configured to actuate between an open state and a closed state. In the open state, the switch 410 causes voltage to be provided on a signal line 120 from the photosensor apparatus 110 to a system monitor 122 (as shown in
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An emitter or drain of the transistor 412 is connected to resistors 416 and 418. An opposite end of the resistor 416 is connected to a light emitting diode 420, which has a cathode connected to the ground or a separate ground. The light emitting diode 420 is configured to illuminate when the photoresistor(s) 114 sense light, indicating that the photosensor apparatus 110 is operational. The light emitting diode 420 may be a green light emitting diode and the resistor 416 may have a value of 470 ohms.
The resistor 418 is configured to be electrically connected to a base or gate of a transistor 422. The resistor 418 may have a value of 22 kilo-ohms, for example. An emitter or drain of the transistor 422 is connected to the same ground as the light emitting diode 420 and the capacitor 415 or a separate ground. Additionally, a collector or a source of the transistor 422 is electrically connected to an output end of the coil 408 of the relay 406. The collector or source of the transistor 422 may also be electrically connected to an anode of a diode 424, which is connected in parallel with the coil 408 of the relay 406. A cathode of the diode 424 is connected to the input end of the coil 408 and the first side (e.g., the input lead) of the photoresistor(s) 114.
During operation, the photoresistor(s) 114 do not allow current from the voltage source to pass when light is not detected. This causes the transistors 412 and 422 to prevent current flow to ground, thereby keeping the switch 410 of the relay 406 in the open state. In the open state, the signal line 120 does not have a signal, and thus there is no indication of a detected light of the indicator lamp 108. When light from the indicator lamp 108 is detected, a resistance of the photoresistor(s) 114 drops, which enables current to flow. The current causes the transistors 412 and 422 to activate or turn on. Further, the current causes the light emitting diode 420 to illuminate. Activation of the transistors 412 and 422 causes the switch 410 of the relay 406 to switch to a closed state, which causes a voltage to be applied to the signal line 120, thereby creating an alert or alarm signal for the monitoring system 122.
The light sensing circuit 115 of
The capacitor 415 in conjunction with the transistors 412 and 422 and the resistors 414, 416, and 418 are configured to provide a smoothing function that keeps the switch 410 of the relay 406 in the closed state even when the photoresistor(s) 114 are not detecting light between flashes. The capacitor 415 is configured to store charge that is dissipated when the photoresistor(s) 114 fail to detect light, thereby mirroring open circuits with respect to the voltage source. The current from the capacitor 415 is discharged through the gates or bases of the transistors 412 and 422 to keep the transistors 412 and 422 switched on. This enables a voltage from the voltage source to charge the coil 408 of the relay 406, keeping the switch 410 in the closed state to ensure that a continuous alert or alarm signal is provided on the signal line 120. The output switching times of the transistors 412 and 422 in conjunction with the resistors 416 and 418 ensure that current from the capacitor 415 is discharged at a slower rate, thereby keeping the switch 410 of the relay 406 switched to the closed state for a longer period of time, such as 500 milliseconds to a few seconds, corresponding to a period of time when the indicator lamp 108 is not illuminating the amber/orange light 204.
The limited discharge of the capacitor 415 ensures that the relay 406 is not switched closed when the indicator lamp 108 is turned off. When the capacitor 415 is fully discharged, the transistor 412 switches off, thereby switching off the transistor 422 and preventing current flow from the voltage source through the coil 408 of the relay 406. When this occurs, the switch 410 moves to the open state, which causes zero (or near zero) voltage to be applied to the signal line 120, indicating that there is no current alarm or alert condition.
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The application 124 is configured to display an indication of the alert and/or alarm received via the signal line 120. In some embodiments, the monitoring system 122 is connected to a plurality of photosensor apparatuses 110 via respective signal lines 120. Such a configuration provides for the concurrent monitoring of a plurality of laboratory instruments 102. Each signal line 120 is connected to a separate port or circuit board pin of the monitoring system 122. This configuration enables the monitoring system 122 to determine which laboratory instrument 102 activated its indicator light 108 based on which port/pin received an alarm/alert signal. Accordingly, the application 124 identifies which of the laboratory instruments 102 corresponds to the alarm/alert. The application 124 may display the alarm/alert in a user interface, such as the user interface 600 of
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The network 126 is communicatively coupled to one or more client devices 128. The application 124 on the client device 128 is configured to display the alert/alarm status of the laboratory instrument(s) 102, as provided by the monitoring system 122. The client device 128 may include a memory device storing machine-readable instructions. A processor of the client device 128 is configured to execute the instructions to cause the application 124 to perform the operations described herein. In some embodiments, the application 128 is configured to receive status updates from the monitoring system 122, including indications as to when alert/alarm signals are received. The disclosed configuration enables an operator to remotely monitor the laboratory instrument(s) 102 using the application 124 that has received status updates from the monitoring system 122 when at least one operator is not present and in close proximity to the instrument(s) to monitor when an indicator light has been activated.
The procedure 700 begins when the light control tube 112 of the photosensor apparatus 110 is coupled or placed adjacent to an indicator light 108 of a laboratory instrument 102 (block 702). At this point, the indicator light 108 is off and the photosensor apparatus 110 causes the relay 406 (or switch) of
However, when light is detected, current flowing through the light sensing circuit 115 causes the relay 406 to switch to a closed state (block 708). Closing of the relay 406 causes a voltage to be applied to a signal line 120, which constitutes an alert/alarm signal 709 (block 710). As discussed above, the alert/alarm signal 709 is transmitted to the monitoring system 122 to provide an indication of a detected analyte, such as bacteria, located in a donated platelet sample. The photosensor apparatus 110 then determines via the photoresistor(s) 114 whether light is still detected (block 712). If light is still detected, the photosensor apparatus 110 causes the relay 406 to stay in the closed state to maintain the generation of the alert/alarm signal 709.
However, when light is no longer detected, the photosensor apparatus 110 determines if the light has been off for a duration that is shorter than a discharge voltage capacity of the capacitor 415 (and/or on/off state transitions of the transistors 412 and 422) (block 714). If the light has not been off for a duration that is shorter than the discharge voltage capacity of the capacitor 415, the photosensor apparatus 110 cause the relay 406 to stay in the closed state. However, when the light has been off for a duration that is longer than the discharge voltage capacity of the capacitor 415, the photosensor apparatus 110 causes the relay 406 to switch to the open state, thereby terminating the alert/alarm signal 709. The example procedure 700 continues until the photosensor apparatus 110 is powered off or removed from the indicator light 108 of the laboratory instrument(s) 102.
It will be appreciated that all of the disclosed methods and procedures described herein can be implemented using one or more computer programs or components. These components may be provided as a series of computer instructions on any computer-readable medium, including RAM, ROM, flash memory, magnetic or optical disks, optical memory, or other storage media. The instructions may be configured to be executed by a processor, which when executing the series of computer instructions performs or facilitates the performance of all or part of the disclosed methods and procedures.
It should be understood that various changes and modifications to the example embodiments described herein will be apparent to those skilled in the art. Such changes and modifications can be made without departing from the spirit and scope of the present subject matter and without diminishing its intended advantages. It is therefore intended that such changes and modifications be covered by the appended claims.
This application claims priority to and the benefit as a non-provisional application of U.S. Provisional Patent Application No. 63/330,161, filed Apr. 12, 2022, the entire contents of which are hereby incorporated by reference and relied upon.
Number | Date | Country | |
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63330161 | Apr 2022 | US |