The present invention relates generally to lighting systems, and in various embodiments to systems for providing mixed light for illumination, protection from pathogens, and disinfection.
It is known that certain wavelength ranges of light, particularly ultraviolet (UV) light, are germicidal—i.e., capable of killing or inactivating pathogens such as bacteria, molds, spores and viruses, rendering them incapable of causing disease. Illumination devices emitting germicidal light are frequently used to decontaminate medical tools and environmental surfaces. UV radiation is dangerous to humans, and some wavelength bands are more dangerous than others. As a result, broadband germicidal UV applications are typically deployed in oven-like devices that receive items to be decontaminated and are closed when the radiation is activated, thereby shielding personnel from harm. Although automated UV-based room-decontamination systems have been developed, these generally are not used when people are present. See, e.g., Livingston et al., “Efficacy of an ultraviolet-A lighting system for continuous decontamination of health care-associated pathogens on surfaces,” Am. J. Infection Control, 48:337-339 (2020). Unfortunately, recontamination can occur quickly following device operation once people return and resume their activities.
The most effective germicidal wavelength band, UV-C (100-280 nm), is also the most dangerous to humans. The UV-A band (315-400 nm), on the other hand, can be safe for use in limited doses and radiant flux, when people are present, and is known to have antimicrobial activity. Accordingly, it is possible to safely integrate UV-A lighting with general illumination, but the lighting sources used for these different wavelength ranges are different. Their outputs must be combined in a manner that preserves the quality of ambient light for affected personnel while ensuring safety.
An increasing number of light fixtures utilize LEDs as light sources due to their lower energy consumption, smaller size, improved robustness, and longer operational lifetime relative to conventional filament-based light sources. Conventional LEDs emit light at a particular wavelength, ranging from, for example, red to UV light. However, for purposes of general illumination, the monochromatic emitted light by LEDs must be converted to broad-spectrum white light.
Embodiments of the present invention combine UV-A and white light with an adjustable CCT value so that any adverse effects from the UV-A radiation are mitigated that is, tunable adjustments to the output of the non-UV LEDs, or to all of the LEDs, result in an overall mixed output conforming to a target CCT value. In one embodiment, the LED illumination device employs an LED array having multiple LEDs that can be controlled individually or in a group to generate white light having a tunable CCT value within a range. Optionally, each of the LEDs may be disposed within a “cup-shaped” (e.g., parabolic) reflector for reducing “crosstalk” interactions between the light emitted from an LED and the photoluminescent material(s) disposed above a neighboring LED. In addition, the reflector may be made of a high-reflectivity material so as to redirect upward light from the respective LED, thereby achieving at least partial collimation of the beam. The LEDs may operate in a normal mode in which only some UV-A LEDs are active and produce UV radiation at a level harmless to humans, while the other LEDs are operated to provide general illumination; and in a “boost” mode in which red and UV-A LEDs are active and the latter are operated at maximum power.
In various embodiments, the LEDs and/or photoluminescent material(s) are encapsulated within a waveguide material made of, e.g., silicone. Light emitted from the LEDs, including unconverted light and light converted by the photoluminescent material(s), can be mixed in a mixing region inside the waveguide and then directed to an output region for outputting white light for illumination. The illumination device may also include control circuitry for varying a parameter (e.g., the amplitude and/or duty cycle of the applied current or voltage) associated with each LED (or, in some embodiments, each group of the LEDs), thereby adjusting the CCT value of the mixed light to a target value.
The term “color” is used herein to denote the monochromatic or peak wavelength (or wavelengths) of light emitted by one or more LEDs. In addition, the term “uniform,” as used herein, refers to a light intensity distribution whose lower and upper intensity limits are within a factor of four, preferably within a factor of two of each other. As used herein, the terms “approximately,” “roughly,” and “substantially” mean±10%, and in some embodiments, ±5%. Reference throughout this specification to “one example,” “an example,” “one embodiment,” or “an embodiment” means that a particular feature, structure, or characteristic described in connection with the example is included in at least one example of the present technology. Thus, the occurrences of the phrases “in one example,” “in an example,” “one embodiment,” or “an embodiment” in various places throughout this specification are not necessarily all referring to the same example. Furthermore, the particular features, structures, routines, steps, or characteristics may be combined in any suitable manner in one or more examples of the technology. The headings provided herein are for convenience only and are not intended to limit or interpret the scope or meaning of the claimed technology.
In the drawings, like reference characters generally refer to the same parts throughout the different views. Also, the drawings are not necessarily to scale, with an emphasis instead generally being placed upon illustrating the principles of the invention. In the following description, various embodiments of the present invention are described with reference to the following drawings, in which:
In some embodiments, the LEDs 104 are electrically coupled to control circuitry 112 in the strip lighting device(s) 102. The control circuitry 112 may be configured to control operation of the LEDs 104 (e.g., by regulating the amplitude and/or duty cycle of the current and/or voltage applied to the LEDs 104), thereby regulating a characteristic (e.g., intensity or brightness) of the light emitted from the LEDs 104. For example, the control circuitry 112 may adjust the brightness of individual LEDs using pulse width modulation (PWM). For example, the control circuitry 112 may rapidly turn individual LEDs on and off at a high frequency that is imperceptible to humans. In this example, the brightness of the individual LEDs 104 may be changed by adjusting the ratio of on-time to off-time within a particular cycle (sometimes referred to as a “duty cycle”). The higher the ratio of on-time to off-time, the brighter the LED. Conversely, lowering the ratio of on-time to off-time dims the LED. Thus, the duty cycle may positively correlate to the average flux of the LED being controlled. The control circuitry 112 may vary the ratio of on-time to off-time based on control signals received from the external device 110 via the connectors 108. In one embodiment, the control circuitry 112 is implemented in circuitry that is external to the illumination system 100. For example, circuitry in the external device 100 may be configured to regulate the current and/or voltage applied to the LEDs 104, thereby directly controlling operations thereof. In this case, the control circuitry 112 may be omitted from the illumination system 100 altogether.
The LEDs 104, control circuitry 112, and/or the connectors 108 may be all mounted to the circuit board 106. For example, the circuit board 106 may include one or more conductors to electrically couple the components mounted thereto. In addition, the circuit board 106 may be flexible to enable the illumination system 100 to conform to uneven surfaces. Referring to
The strip lighting device(s) 102 in the illumination system 100 may have particular dimensions to enable a wide range of applications. For example, the lighting devices 102 may have a depth of no more than approximately 1 inch, a length of no more than approximately 25 inches, and a width of no more than approximately 4 inches. It should be appreciated that the strip lighting devices 102 may be constructed with other dimensions, and may be two-dimensional arrays of LED groups rather than one-dimensional strips. In various embodiments, the LEDs 104 are separated by a distance (e.g., 25 millimeters (mm) or 3 mm). In addition, each of the LEDs 104 may be configured to emit light with the same or different characteristic (e.g., wavelength, CCT value, etc.). As shown in
The LEDs 104 may be operated individually or in a grouped manner. For example, each LED may be independently coupled to the control circuitry 112 such that the control circuitry 112 can separately control individual LEDs. Alternatively, some of the LEDs 104 may be wired together to allow the control circuitry 112 to control them as a single unit; different groups may or may not share one or more LEDs 104.
With reference to
As shown in
The planar remote phosphor architecture illustrated in
When the planar remote phosphor architecture illustrated in
The light emitted from an LED 104 may interact with the photoluminescent material(s) disposed above a neighboring LED, cause a “crosstalk” interaction, and thereby result in additional colors. To reduce the crosstalk interaction, with reference to
In some embodiments, the geometry of the cup-shaped reflectors 302 is configured to provide a uniform distribution of the light intensity at a specific distance, D, above the LED 104 where the conversion layer(s) 204 is typically disposed. In one embodiment, the reflector 302 is a parabolic reflector (i.e., a reflecting optic whose reflective surface forms a truncated paraboloid), and the LED 104 is placed at or near the focus of the paraboloid. Thus, a light beam emitted from the LED 104 onto the reflector 302 may be redirected upward for at least partial collimation of the beam.
Referring to
With renewed reference to
In one implementation, the entire circuit board 106 is encapsulated inside the waveguide; the illumination system 100 may include a heat-conducting path connecting the bottom surface of the circuit board 106 to an outer surface of the waveguide for dissipating heat generating by the LEDs 104. In one embodiment, the heat-conducting path is formed by using a heat conductive material as a part of the waveguide material and disposing the circuit board 106 to be in directly contact with the waveguide.
As discussed above, the LEDs 104 mounted on the circuit board 106 may be controlled individually or in a group manner to generate light having a tunable CCT value within a range. In some embodiments, the control circuitry 112 adjusts the intensity of the light emitted from one or more of the LEDs 104-1, 104-2, 104-3 by varying the amplitude and/or duty cycle of the current and/or voltage associated therewith. In addition, the control circuitry 112 may include a look-up table that maps particular target CCT values to a set of intensity ratios for the LEDs within the LED array. Thus, when the control circuitry 112 receives information indicative of a desired CCT value, it may access the look-up table to retrieve the corresponding intensity ratios, and, based thereon, adjust the intensities of the LEDs.
Refer now to
The illustrated linear sequence is only one example of groupings, however; in other implementations, the groupings are spread across linear LED sequences as shown in
Suitable LEDs are as follows:
In some embodiments, the controller 112 has three output channels A, B, C. Channel A controls the blue LEDs, channel B controls the red LEDs, and channel C controls the UV-A LEDs. Once again, the control circuitry 112 adjusts the intensity of the light emitted from one or more of the LEDs 104-1, 104-2, 104-3, 104-U by varying the amplitude and/or duty cycle of the current and/or voltage associated therewith. In some embodiments, only the amplitude and/or duty cycle of the visible-light LEDs 104-1, 104-2, 104-3 is controlled; in other embodiments, the amplitude and/or duty cycle of all LEDs is controlled.
In the configuration 4002 shown in
The conversion layers with photoluminescent materials may be disposed above some or all of the LEDs, and following conversion, light from all LEDs is mixed in the waveguide as described above. For example, blue light or UV-A light may interact with phosphor material, and some of it is converted to a different color. The converted light and the remaining blue light are mixed with the red and UV-A light and extracted out from the waveguide plate to form white light illumination. The red light is used to tune the white light color coordinates to fit the required CCT and to improve CRI values, so it may be necessary to control the amplitude and/or duty cycle only of the red LEDs 104-1. Additional white LED at a specific CCT, may be assembled on the PCB to enable True Tunable White (TTW) functionality—i.e., the ability to tune the CCT along the black-body curve of white light from deep warm (e.g., 1800K) to far cool (e.g., 6500K) with small deviation, i.e., below 1 Macadams ellipse).
The UV-A light may interact with the photoluminescent material and increase the amount of converted light. This will change the CCT of the light. In this case the intensity of the red light may be increased to shift the color coordinates to fit the required CCT. One option is to use a photoluminescent material having a very low excitation level at the UV-A wavelength (e.g., Yttrium Aluminum Oxide:Cerium Y3Al5O12:Ce), as shown in
The LED configurations 400 can be organized into a lighting fixture or “luminaire.” In a “normal” mode of operation, the luminaire can provide conventional white light and germicidal UV-A light. For example, the UV-A emission may be ˜7 W together with the required intensity of white light. As shown in
Operating illumination that includes UV light should comply with safety regulations such as the IEC 62471 standard, which covers photobiological safety of lamps and lamp systems. According to this standard, near-UV emission with irradiance values below 10 W/m2 is exempt from any exposure time limitation. Illumination devices in accordance with embodiments hereof use a planar structure that emits the light uniformly from the planar out-coupling area. In this case, the total radiant flux from the illumination device divided by the area of the planar out-coupling area should provide an irradiance value below the regulatory maximum. For example, if the planar out-coupling area is 0.6 m×0.6 m=0.36 m2, then the total maximum radiant flux is 3.6 W, which results in a maximum irradiance of 10 W/m2.
Representative circuitry 900 for controlling an illumination system with these features is shown in
The action selected by logic 915 may be to change the current activation pattern of LEDs. This is effected by an interface board 920, which contains a switch matrix for controlling the LEDs 925 associated with a single room or with multiple rooms of a facility. The interface board 920 may also receive commands from the controller 112 to change the current activation pattern. Finally, the interface board 920 may receive feedback from the LEDs 925, e.g., their operating temperature (which may be communicated by temperature sensors on the LED boards), and may take an action, such as activating or deactivating a cooling fan 930 for the LEDs. Logic 915 may be configured to, for example, change the operating mode in response to signals from, e.g., two independent sensors 910 indicating the absence of personnel in the room 820. Requiring mutual corroboration between two independent sensors before the lighting state is changed avoids actions based on spurious or transient sensor readings. Particularly if the boost state is accompanied by the red warning light, the chance of harm to humans is small.
An illustrative configuration 950 of the interface board 920 is shown in
Thus, a positive selector signal from logic 915 or the controller 112 closes the switch 960, but the inverted signal leaves the switch 955 open so that normal mode is achieved: the drive current is shorted to ground above CH4, so that only CH1, CH2, and CH3 receive power. A negative selector signal, corresponding to boost mode, provides a low-resistance path around CH2 and CH3 so that only CH1 and CH4 are operated. In order to use the same LED driver 905 in this configuration, the voltage drop for CH2 and CH3 should be close to the voltage drop for CH4.
The control circuitry 112 may include or be connected to one or more modules implemented in hardware, software, or a combination of both. For embodiments in which the functions are provided as one or more software programs, the programs may be written in any of a number of high level languages such as PYTHON, FORTRAN, PASCAL, JAVA, C, C++, C#, BASIC, various scripting languages, and/or HTML. Additionally, the software can be implemented in an assembly language directed to the microprocessor resident on a target computer; for example, the software may be implemented in Intel 80×86 assembly language if it is configured to run on an IBM PC or PC clone. The software may be embodied on an article of manufacture including, but not limited to, a floppy disk, a jump drive, a hard disk, an optical disk, a magnetic tape, a PROM, an EPROM, EEPROM, field-programmable gate array, or CD-ROM. Embodiments using hardware circuitry may be implemented using, for example, one or more FPGA, CPLD or ASIC processors.
The effectiveness of embodiments of the invention in reducing pathogen levels and their infectivity is illustrated in
The viral pathogen tested was hepatitis C virus (“HCV”). In a representative experiment, HCV virus is generated in vitro, in human liver cells. RNA is produced from plasmid DNA and elctroporated the RNA into human liver cells. At day 10 post-electroporation, the viruses are secreted into a growth medium, concentrated and stored as virus stocks. To test infection, a virus stock is used to infect human liver cells in culture.
Infected cells are identified by immunostaining with human serum derived from infected hepatitis C patients, followed by exposure to a secondary anti-human antibody with flourescence signal. The infected cells are visualized under a flourescence microscope. To titer the number of infectious viruses, a Focus Forming Unite (FFU) assay is performed, where cells are infected and the number of foci (fluorescence signal of adjacent infected cells) are counted; these represent the number of infectious viruses.
In one procedure, virus stock was diluted to 102-103 infectious virueses per 30 μl well in a 96-well plate. The samples were placed inside a fume hood. Radiation was applied in the different modes noted above and the medium containing irradiated viruses was transferred to human Huh7.5 liver cells that were preseeded in a 96-tissue culture plate at 5×104 cell/well. At 2, 4 and 6 days post infection, the cells were immunostained with human serum derived from infected hepatitis C patients, followed by a secondary anti-human antibody with a flourescence signal. The infected cells were visualized and counted using INCUCYTE Live-Cell Analysis. The infection percentage was calculated as the number of positive infected cells in each treatment compared to the number of infected cells in an untreated control.
As shown in
Hence, with reference to
The terms and expressions employed herein are used as terms and expressions of description and not of limitation, and there is no intention, in the use of such terms and expressions, of excluding any equivalents of the features shown and described or portions thereof. In addition, having described certain embodiments of the invention, it will be apparent to those of ordinary skill in the art that other embodiments incorporating the concepts disclosed herein may be used without departing from the spirit and scope of the invention. Accordingly, the described embodiments are to be considered in all respects as only illustrative and not restrictive.
Number | Date | Country | Kind |
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2013198.3 | Aug 2020 | GB | national |
This application claims priority to and the benefits of, and incorporates herein by reference in their entireties, U.S. Provisional Application No. 62/993,295, filed on Mar. 23, 2020, and UK Patent Application No. 2013198.3, filed on Aug. 24, 2020. This application is also a continuation-in-part of U.S. Ser. No. 16/850,760, filed on Apr. 16, 2020, which is a continuation-in-part of U.S. Ser. No. 16/750,031, filed on Jan. 23, 2020, which is itself a continuation of U.S. Ser. No. 16/425,083, filed on May 29, 2019, which claimed priority to U.S. Provisional Application Nos. 62/811,551 (filed Feb. 28, 2019) and 62/677,405 (filed May 29, 2018). The entire disclosures of all of the foregoing documents are hereby incorporated by reference.
Number | Date | Country | |
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62993295 | Mar 2020 | US | |
62811551 | Feb 2019 | US | |
62677405 | May 2018 | US |
Number | Date | Country | |
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Parent | 16425083 | May 2019 | US |
Child | 16750031 | US |
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Parent | 16850760 | Apr 2020 | US |
Child | 17209435 | US | |
Parent | 16750031 | Jan 2020 | US |
Child | 16850760 | US |