LINKED GROWTH FACTOR GENES ON CHROMOSOME 5

Information

• Research Project
• 3508332

• ApplicationId

  3508332

• Core Project Number

  R44HG000508

• Full Project Number

  5R44HG000508-03

• Serial Number

  508

• FOA Number

• Sub Project Id

• Project Start Date

  4/1/1991 - 34 years ago

• Project End Date

  3/31/1993 - 32 years ago

• Program Officer Name

• Budget Start Date

  4/1/1992 - 33 years ago

• Budget End Date

  3/31/1993 - 32 years ago

• Fiscal Year

  1992

• Support Year

  3

• Suffix

• Award Notice Date

  3/26/1992 - 33 years ago

Organizations

• GENELABS TECHNOLOGIES, INC.

Chromosome 5 comprises about 3% by length of the human genome. We propose to construct an arrayed set of yeast artificial chromosome (YAC) clones specific to this chromosome. A library of approximately 3,000 chromosome 5- specific YACs, comprising about five fold coverage of the chromosome, will be constructed. YAC contigs will be derived from part of the 5q23-q33 region of the chromosome using an initial set of five probes from growth factor/receptor genes within this region. End-specific probes will be derived from these initial anchor loci and will be sued to walk outwards within the arrayed YAC library. Sequence tagged sites will be used in conjunction with a novel cDNA enrichment scheme, to select the cDNAs that are encoded by this region in T-cells and to identify novel cDNAs for encoding new growth factors/receptors.

IC Name

• Activity

  R44

• Administering IC

  HG

• Application Type

  5

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  172

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  SSS

• Study Section Name

• Organization Name

  GENELABS TECHNOLOGIES, INC.

• Organization Department

• Organization DUNS

• Organization City

  REDWOOD CITY

• Organization State

  CA

• Organization Country

  UNITED STATES

• Organization Zip Code

  940634737

• Organization District

  UNITED STATES