Linking high-risk young women to HIV prevention and care for comorbid conditions

Information

  • Research Project
  • 9040235
  • ApplicationId
    9040235
  • Core Project Number
    R21HD082866
  • Full Project Number
    5R21HD082866-02
  • Serial Number
    082866
  • FOA Number
    RFA-AI-14-010
  • Sub Project Id
  • Project Start Date
    3/25/2015 - 9 years ago
  • Project End Date
    2/28/2017 - 7 years ago
  • Program Officer Name
    CHAKHTOURA, NAHIDA ABDO
  • Budget Start Date
    3/1/2016 - 8 years ago
  • Budget End Date
    2/28/2017 - 7 years ago
  • Fiscal Year
    2016
  • Support Year
    02
  • Suffix
  • Award Notice Date
    3/17/2016 - 8 years ago

Linking high-risk young women to HIV prevention and care for comorbid conditions

? DESCRIPTION (provided by applicant): HIV is increasing in the Western Cape province of South Africa, with new infections occurring mostly among young women from poor communities. Substance use and victimization are key drivers of risk for HIV in this population, yet these conditions are rarely treated. As untreated substance use and victimization negatively impact on the uptake of HIV prevention, it is imperative to expand HIV prevention for young women to include linkage to treatment for these co-occurring conditions. Seek, test, treat and retain (STTR) approaches have been used to engage high-risk populations in HIV prevention and treatment, but have not yet been used as a model for engaging high-risk young women in HIV prevention and treatment for co-occurring substance use and victimization. The goal of this project is to address this gap by adapting a women-focused STTR HIV prevention model to include linkage to substance use and victimization services. Using the ADAPT-ITT framework to guide intervention adaptation, we will first conduct in-depth interviews with health providers and focus groups with young women with substance use disorders and victimization experiences to explore their perceptions of barriers to engagement and retention in services for HIV, substance use and victimization among young women. Findings will guide decisions about how to adapt the Women's Health CoOp, an STTR model for HIV prevention, to facilitate linkage to treatment for substance use and victimization. Next, we will administer the adapted intervention in a series of focus groups with high-risk young women. Findings will be used to further adapt the model to enhance relevance, fit, and acceptability for the target population. Finally, we will test the inital feasibility of this adapted STTR model for HIV prevention by seeking 60 high-risk young women through street outreach in selected communities and enrolling these young women into the STTR intervention where they will be tested for HIV, pregnancy and recent substance use and assessed for trauma related to victimization and HIV risk behavior. They will then receive the HIV prevention intervention that includes preparation and linkage to treatment for substance use and victimization. Immediately after receiving the last intervention session, they will complete a brief assessment. Thereafter, participants will receive case management services that provide ongoing support for service use and target structural barriers to retention in services. Participants will be assessed three months after the last assessment to examine whether the model has the potential for facilitating linkage to substance use and victimization services.

IC Name
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
  • Activity
    R21
  • Administering IC
    HD
  • Application Type
    5
  • Direct Cost Amount
    160624
  • Indirect Cost Amount
    9617
  • Total Cost
    170241
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    865
  • Ed Inst. Type
  • Funding ICs
    NICHD:170241\
  • Funding Mechanism
    Non-SBIR/STTR RPGs
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    MEDICAL RESEARCH COUNCIL OF SOUTH AFRICA
  • Organization Department
  • Organization DUNS
    635909489
  • Organization City
    CAPE TOWN
  • Organization State
  • Organization Country
    SOUTH AFRICA
  • Organization Zip Code
  • Organization District
    SOUTH AFRICA