LIPOPHILIC CALCIUM FLUOROIONOPHORES

Information

• Research Project
• 2188566

• ApplicationId

  2188566

• Core Project Number

  R43GM050609

• Full Project Number

  1R43GM050609-01

• Serial Number

  50609

• FOA Number

• Sub Project Id

• Project Start Date

  12/1/1993 - 30 years ago

• Project End Date

  11/30/1994 - 29 years ago

• Program Officer Name

• Budget Start Date

  12/1/1993 - 30 years ago

• Budget End Date

  11/30/1994 - 29 years ago

• Fiscal Year

  1994

• Support Year

  1

• Suffix

• Award Notice Date

  11/22/1993 - 30 years ago

Organizations

• COVALENT ASSOCIATES, INC.

We propose to synthesize and test new lipophilic fluorescent ionophores for measuring calcium ion concentrations in aqueous solutions. The ionophores are designed to be soluble in synthetic membranes and to respond selectively to Ca2+ in a contacting aqueous solution by undergoing a shift in absorption and emission to longer wavelengths. The proposed compounds will be of primary interest for incorporating into a fiber optic chemical sensor (FOCS). A FOCS device will be of use for determining the concentration of calcium ion in biological fluids in vitro and ultimately in vivo. A device based on this design would be valuable in the intensive care unit or other hospital facility.

IC Name

• Activity

  R43

• Administering IC

  GM

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  821

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  ZRG7

• Study Section Name

• Organization Name

  COVALENT ASSOCIATES, INC.

• Organization Department

• Organization DUNS

• Organization City

  WOBURN

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  01801

• Organization District

  UNITED STATES