The present invention relates to a liquid container comprising a container body and an instilling opening member.
It has conventionally been proposed to provide a sealing portion for a container body to block the interior of the container from ambient air in order to maintain a sterile condition of liquid contained in the container body and preserve the sterile liquid for an extended time. However, even if the sealing portion is provided, ambient air flows into the container body or liquid exposed to ambient air flows back into the container body when the sealing portion is broken, as in the case of ordinary containers. Thus, when the incoming ambient air or the backflow liquid mixes with the liquid within the container body, the entire liquid contained in the container body can be contaminated by microbes or the like present in the air or the liquid.
Where the container is an eyedrops container, for example, an instilling opening of the eyedrops container may sometimes contact tears or eyelashes in time of instillation to be contaminated by microbes or the like. As a result, when the liquid having contacted tears or eyelashes flows back into the container body, the entire liquid contained in the container body will be contaminated and the sterile condition in the interior of the container body cannot be maintained. In addition, once microbes or the like flow into the container body, the microbial contamination is likely to spread over time.
On the other hand, a preservative can be added to the liquid prior to being stored in the container body to cope with the situation. However, it is desirable to avoid addition of the preservative as much as possible, taking influences of the preservative on human bodies into consideration.
In view of the above, various types of liquid containers have been proposed for the purpose of preventing the backflow into the container body. For instance, one proposal is to provide a check valve function for the sealing portion (Patent Document 1), and another proposal is to provide a check valve for preventing liquid having flowed from the sealing portion to the instilling opening member from flowing back into the container body (Patent Document 2).
Patent Document 1: Japanese Patent Publication “Kokai” No. 2003-169839
Patent Document 2: Japanese Patent Publication “Kokai” No. 2003-26250
However, according to Patent Document 1, the sealing portion is formed of a check valve made of an elastic member with an openable and closable pinhole. Thus, in order to open or close the check valve, a communicating needle is required which is movable from the instilling opening to the container body. However, the communicating needle is likely to contact ambient air as positioned close to the instilling opening of the check valve. The communicating needle having contacted ambient air is subsequently moved from the instilling opening toward the container body, and thus a possibility of contaminating the interior of the container body.
According to Patent Document 2, liquid having been contaminated adjacent the instilling opening can, prima facie, be prevented from flowing back toward the container body beyond the check valve. However, since the check valve is provided closer to the instilling opening than the sealing portion, it is necessary to form the sealing portion and the check valve separately to be separable from each other so that the sealing portion may be opened. This arrangement creates a possibility that the interior of the container body is contaminated since the sealing portion is opened with the unsealing portion (the member 10 in Patent Document 2) being exposed to ambient air.
When opening the sealing portion, the user of the liquid container may inadvertently separate the sealing portion and check valve. Then, the liquid inside the container body and in the vicinity of the sealing portion of the container body will be exposed to ambient air.
The object of the present invention is to provide a liquid container in which liquid has a reduced chance of becoming contaminated.
A characteristic construction of a liquid container according to the present invention lies in comprising a container body including a liquid storage space formed therein, and an instilling opening member, wherein the liquid container further comprises a sealing portion for hermetically confining liquid in the interior of the container body, an unsealing member for opening the sealing portion, and a check valve provided at a portion closer to the liquid storage space than the sealing portion and the unsealing member for allowing the unsealing member to open the sealing portion when the instilling opening member is pushed toward the container body, and for preventing the liquid from flowing back to the interior of the container body.
With the above-noted construction, both the unsealing member and the sealing portion are positioned closer to an instilling opening formed in the instilling opening member than the check valve. Therefore, an opening operation can be executed without operating a portion between the check valve and the container body in breaking the sealing portion with the unsealing member by pushing in the instilling opening member toward the container body. This substantially eliminates the possibility of spreading contamination over the interior of the container body through the check valve in the opening process.
That is, the liquid may be maintained sterile for a long time without adding any chemicals such as a preservative thereto.
The instilling opening member in the above-noted construction is preferably shiftable between a first position to maintain the unsealing member not piercing the sealing portion and a second position to allow the unsealing member to pierce the sealing portion relative to the container body.
More particularly, when the unsealing member is in the position not to pierce the sealing portion, the sealing portion can maintain the sealed state, and thus the liquid within the container body can be maintained in an uncontaminated state. When the unsealing member pierces the sealing portion, the sealed state is canceled to allow the liquid to be used. Since the position shifting operation is carried out by pushing in the instilling opening member toward the container body, the position can be shifted without exposing the sealing portion to the outside. This can reduce the possibility of contamination occurring in the space within the instilling opening member or adjacent the sealing portion.
In the above-noted construction, the unsealing member may pierce the sealing portion from the container body toward the instilling opening member, or may pierce the sealing portion from the instilling opening member toward the container body.
According to the above construction, the unsealing member is provided at the side of the container body while the sealing portion is provided at the side of the instilling opening member, whereby the unsealing member is shifted from the first position spaced from or contacting the sealing portion to the second position to pierce the sealing portion by pushing in the instilling opening member to the container body. In the latter case as well, the construction acts in a similar way by swapping the positions of the sealing portion and unsealing member.
After the unsealing member pierces the sealing portion, the sealed condition of the sealing portion is cancelled to allow the liquid within the container body to move toward the instilling opening formed in the instilling opening member through the sealing portion. At this time, since the check valve is not affected by the sealing portion or the unsealing member, the liquid having reached the sealing portion does not flow back into the container body through the check valve, and also ambient air does not flow into the container body. Thus, the sterile condition can be maintained within the container body.
In employing such a construction, the unsealing member and the sealing portion may be distributed to the instilling opening member and the container body, respectively, or may be provided together on either side of the instilling opening member and the container body. Further, the instilling opening member may act as the unsealing member.
It is preferable that the container body has a flexible portion for varying the capacity of the container body in response to an amount of liquid contained in the interior of the container body.
When the check valve prevents the backflow of the liquid having reached adjacent the sealing portion or the inflow of the air present in the instilling opening member into the container body, the amount of the liquid within the container body is reduced, which results in a decreased inner pressure.
When the liquid is reduced by a small amount, the inner pressure is slightly decreased within the container body thereby to allow the check valve to fully perform its function. However, when a large amount of liquid is reduced, a force to draw the liquid toward the interior of the container body is produced in response to the decrease of the inner pressure of the container body, if the container body has excellent shape-memory properties. As a result, the check valve may not function, or a greater force may be required for discharging the liquid from the container body.
In order to avoid such problems, the container is provided with the flexible portion (a bellows-like container, for example) so that the capacity of the interior of the container body may vary in response to variations of the amount of the liquid present in the container body, thereby to constantly maintain the inner pressure substantially at the same level as atmospheric pressure. Therefore, the check valve functions properly, and the liquid is easily instilled from the container.
Embodiments of a liquid container according to the present invention will be described hereinafter with reference to the drawings.
As shown in
The container body 1 includes a barrel 11 made of a resin forming a liquid storage space for containing mainly a liquid therein, and a cylindrical plug 12 for guiding the liquid such as medical liquid for eyedrops from the barrel 11 to outside of the container body. The barrel 11 and the plug 12 are formed separately from each other and integrated together to constitute the container body 1. The barrel 11 includes a thin-walled flexible portion 13.
The instilling opening member 2 is shaped cylindrical so that a cap 3 can be fitted thereon, and includes an instilling opening 21 formed at one end thereof, and a screw portion 22 formed at the other end thereof to be screwed to the plug 12 of the container body 1. A constricted portion 23 is formed in the interior of the instilling opening member 2 for restricting a flow rate of the liquid. The instilling opening 21 is formed to distil a fixed amount of the medical liquid maintained in the interior of the instilling opening member 2 extending from the constricted portion 23 to the one end thereof.
A check valve 4 is fitted in the plug 12 of the container body 1 for preventing the medical liquid having flowed out of the barrel 11 of the container body 1 toward the instilling opening member 2 from flowing back into the container body 1. A sealing portion 5 made of a resin film is provided for the check valve 4 close to the instilling opening member 2 for hermetically confining the medical liquid within the container body 1. The resin film is desirably broken and opened entirely and widely as a middle portion thereof is ruptured.
The instilling opening member 2 includes an unsealing member 6 therein having a needle portion 61 acting as an unsealing portion. The unsealing member 6 is arranged and fixed so as to move toward and penetrate the sealing portion 5 as the instilling opening member 2 is screwed into the plug 12.
The unsealing member 6 has a seat portion 62 fitted in the screw portion 22 of the instilling opening member 2. The needle portion 61 is mounted upright on the seat portion 62. This allows the unsealing member 6 to accommodate and maintain the needle portion 61 in a position extending downward along the axis of the instilling opening member 2 with the seat portion 62 fitted in the instilling opening member 2.
The seat portion 62 has a bore formed therein to facilitate passage of the liquid from the container body to the instilling opening.
The instilling opening member 2 with the cap 3 screwed thereto is kept in store as partly screwed into the plug 12. In this state, the unsealing member 6 is in a first position or non-piercing state spaced from or contacting the sealing portion 5 (see
In starting to use this liquid container, the instilling opening member 2 is screwed into the plug 12 to move the needle portion 61 of the unsealing member 6 toward the container body 1. As a result, the unsealing member 6 is shifted to a second position to pierce the sealing portion 5 within the plug 12 (see
Thus, the liquid within the container body 1 can be supplied from the sealing portion 5 through the check valve 4 and through the constricted portion 23 of the instilling opening member 2 to the instilling opening 21 to be distilled. At this time, the liquid remains in a space S defined between the constricted portion 23 and the check valve 4, but does not flow back to the container body 1. Also, ambient air does not flow into the container body 1.
Since the container body 1 includes the thin-walled flexible portion 13 which is easily deformable, the capacity of the interior of the container body 1 varies with variations in the amount of liquid in the container body 1 to constantly maintain an inner pressure at substantially the same level as atmospheric pressure. Therefore, air is not drawn from the instilling opening 21 to the interior of the container body 1.
The sealing portion 5 and the unsealing member 6 in the above-noted embodiment may be arranged as shown in
More particularly, in
With this construction, the unsealing member 6 assumes the first position or non-piercing state spaced from or contacting the sealing portion 5 in the instilling opening member 2 in the stored position where the instilling opening member 2 is partly screwed into the plug 12 (see
In starting to use this liquid container, the instilling opening member 2 is screwed into the plug 12 to move the sealing portion 5 toward the container body 1. As a result, the needle portion of the unsealing member 6 is shifted to the second position to pierce the sealing portion 5 (see
At this time, the needle portion 61 is rotated about the axis to pierce the sealing portion 5, and thus may easily open the constricted portion 23 even if the instilling opening member 2 is made of a somewhat rigid material. Therefore, this arrangement is advantageous in that the portion of the sealing portion 5 that is to be formed as the constricted portion 23 and easily exposed to outside when the cap 3 is removed is not easily opened.
In order to use the container with the needle portion 61 piercing the sealing portion 5 and extending through the constricted portion 23, a groove portion 63 is preferably formed in an outer surface of the needle portion 61 along the axial direction to allow the liquid to pass through the constricted portion 23 by way of the groove portion 63.
Various types of conventional check valves may be used instead of the check valve 4 in the above-noted embodiments as long as the liquid is prevented from flowing back into the container body 1.
The unsealing member 6 may have a push-in blade instead of the needle portion 61. Further, it may be maintained in an inclined position instead of the position along the axial direction of the instilling opening member 2 and the plug 12 as long as the sealing portion 5 can be opened as the instilling opening member 2 is pushed in.
Further, in pushing in and opening the instilling opening member 2, the member 2 may be simply pressed into the plug 12, instead of forming the screw portion 22 thereon to be screwed to the plug 12.
As the liquid, various types of liquids other than the medical liquid for eyedrops are applicable.
In forming the flexible portion 13, various modifications are possible such as the container body 1 having a bellows-like portion in part or as a whole, instead of the container body 1 having a partly thinned portion.
On the other hand, the container body 1 may be formed as a container having a cylinder piston, a container having a check valve provided in the bottom, in which the capacity of the interior of the container body 1 may change in response to variations of the liquid amount in the container body thereby to constantly maintain the inner pressure at substantially the same level as atmospheric pressure.
Further, it is desirable to form the portions where the liquid adheres or remains (the instilling opening member 2, check valve 4, unsealing member 6 and plug 12, for example) of an antibacterial resin in order to restrain the liquid contained in the container body 1 from being contaminated by various microbes. As the antibacterial resin, a resin base having an antibacterial substance mixed thereto is generally used.
It is also possible to enhance the antibacterial effect by bringing the liquid moving from the space S defined between the constricted portion 23 and the check valve 4 to the instilling opening 21, into contact with a porous material having an antibacterial effect. Either of organic and inorganic filters may be employed as the porous material, and more particularly, any filters made of non-woven fabric, sponge (pumice) and cotton may be used and fitted on the instilling opening 21, for example.
As noted above, the liquid container of the invention may enhance the preservability of the liquid to allow the liquid to be used in a reliable and uncontaminated condition, thereby to improve handling convenience of the liquid.
The liquid container according to the present invention may be used as an eyedropper or the like used mainly for medical purpose.
[
Side view in vertical section of a liquid container in a stored condition according to Embodiment 1 of the present invention.
[
Side view in vertical section of the liquid container in a start-to-use condition according to Embodiment 1 of the present invention.
[
Side view in vertical section of a liquid container according to Embodiment 2 of the present invention.
1 container body
2 instilling opening member
4 check valve
5 sealing portion
6 unsealing member
13 flexible portion
Number | Date | Country | Kind |
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2004-0655543 | Mar 2004 | JP | national |
Filing Document | Filing Date | Country | Kind | 371c Date |
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PCT/JP05/04074 | 3/9/2005 | WO | 9/8/2006 |