TREA

Liquid drug transfer device with vented vial adapter

Follow

Information

  • Patent Grant
  • 8753325
  • Patent Number
    8,753,325
  • Date Filed
    Wednesday, February 23, 2011
    13 years ago
  • Date Issued
    Tuesday, June 17, 2014
    10 years ago
Information
Abstract
Liquid drug transfer devices including a vented vial adapter having a top wall, a downward depending skirt, and a dual lumen puncturing spike. The top wall includes vent apertures in flow communication with an underlying air filter and protective hoods for covering the vent apertures from splashes. The hood-like hoods are preferably quarter sphere shaped with hood apertures facing radial outwards.
Description
CROSS-REFERENCE TO RELATED APPLICATION

This application is a Section 371 of International Application No. PCT/IL2011/000187, filed Feb. 23, 2011, which was published in the English language on Sep. 1, 2011, under International Publication No. WO 2011/104712 A1, and the disclosure of which is incorporated herein by reference.


FIELD OF THE INVENTION

The invention relates to liquid drug transfer devices in general and liquid drug transfer devices including a vented vial adapter in particular.


BACKGROUND OF THE INVENTION

U.S. Pat. No. 6,139,534 to Niedospial, Jr. et al. illustrates and describes a liquid drug transfer device constituted by a vented vial adapter having a longitudinal vial adapter axis and including a top wall with a series of axial directed vent apertures, an annular air filter underlying the series of vent apertures, a downward depending skirt for telescopically receiving a vial therein, a downward depending central dual lumen puncturing spike and an oppositely directed central liquid transfer port. The dual lumen puncturing spike includes a pair of axial directed adjacent lumens, namely, a liquid transfer lumen and a vent lumen. The liquid transfer port is in flow communication with the liquid transfer lumen. The vent apertures are in flow communication with the vent lumen via the air filter. The vented vial adapter includes an elastomeric pre-split septum for maintaining sterility of vial contents. Use of the vented vial adapter may lead to liquid contents inadvertently draining into one or more of the vent apertures or one or more vent apertures being splashed by liquid contents, thereby wetting the underlying air filter to the detriment of its operation.


Liquid drug transfer devices with vented vial adapters are also illustrated and described in inter alia U.S. Pat. No. 4,834,744 to Ritson, U.S. Pat. Nos. 6,503,240, 6,544,246, 6,655,246, 6,997,917 and 7,799,009 also to Niedospial, Jr. et al., U.S. Pat. No. 7,192,423 to Wong, U.S. Pat. No. 7,452,348 to Hasegawa, US Patent Application Publication No. US 2007/0156112 to Walsh, US Patent Application Publication No. US 2008/0172024 to Yow.


SUMMARY OF THE INVENTION

The present invention is directed toward liquid drug transfer devices including a hitherto described vented vial adapter. The present invention is directed towards provisioning such a vented vial adapter with individual protective hoods for covering its vent apertures for precluding liquid drug contents entering a vent aperture due to draining, splashing, and the like, and wetting its underlying air filter to the detriment of its operation. The present invention can include a manually placed cap for placing on a liquid access port for maintaining contents sterility. Alternatively, the present invention can include an elastomeric pre-split septum for maintaining sterility of vial contents.


The present invention can be equally applied to a wide range of liquid drug transfer devices including vented vial adapters for use with different sized vials, namely, 13 mm, 20 mm, and the like. The liquid drug transfer devices can be constituted by vial adapters per se including female vial adapters, male vial adapters, and the like. Other liquid drug transfer devices include, for example, liquid drug transfer devices illustrated and described in commonly owned U.S. Pat. No. 6,558,365 to Zinger et al., in-line liquid drug transfer devices illustrated and described in commonly owned PCT International Publication No. WO 2005/105014, and the like.





BRIEF DESCRIPTION OF DRAWINGS

In order to understand the invention and to see how it can be carried out in practice, preferred embodiments will now be described, by way of non-limiting examples only, with reference to the accompanying drawings in which similar parts are likewise numbered, and in which:



FIG. 1 is a pictorial representation of a syringe, a vial and a vented female vial adapter having a longitudinal vial axis;



FIG. 2 is a top plan view of the vented vial adapter along the longitudinal vial axis;



FIG. 3 is a longitudinal cross section of FIG. 1's vented vial adapter along line A-A in FIG. 2;



FIG. 4 is a longitudinal cross section of FIG. 1's vented vial adapter along line B-B in FIG. 2; and



FIG. 5 is a pictorial representation of a liquid drug transfer device with a detachable vented vial adapter.





DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS OF THE INVENTION


FIG. 1 shows a syringe 10 constituting a source of physiological fluid, a medicinal vial 20 and a liquid drug transfer device 30 constituted by a vented female vial adapter for use with the syringe 10 and the vial 20. The syringe 10 includes a barrel 11 with a plunger 12 and a male Luer lock connector 13. The syringe 10 can be formed with other types of male connectors. The vial 20 includes an open topped bottle 21 sealed by a vial stopper 22 capped by a metal band 23. The vial 20 contains either a powdered or liquid drug 24 under negative pressure. The syringe 10 typically contains diluent for reconstituting the vial contents 24.



FIGS. 1 to 4 show the vented female vial adapter 30 has a longitudinal vial adapter axis 31 and includes a transverse top wall 32 having a downward depending skirt 33 with flex members 34 for snap fitting onto the vial 20. The vial adapter 30 includes a downward depending dual lumen puncturing spike 36 for puncturing the vial stopper 22 on snap fitting the skirt 33 on the vial 20. The puncturing spike 36 includes a base 36A towards the top wall 32 and terminates in a spike tip 36B. The puncturing spike 36 includes a pair of axial directed lumens, namely, a liquid transfer lumen 37 and a vent lumen 38. The liquid transfer lumen 37 includes a port 37A towards the spike tip 36B. The vent lumen 38 has a port 38A towards the spike tip 36B.


The vial adapter 30 also includes a central axial directed liquid transfer port 39 oppositely directed to the puncturing spike 36 and in flow communication with the liquid transfer lumen 37. The liquid transfer port 39 terminates in a female Luer connector 41 for screw thread engagement with the syringe's male Luer lock connector 13. The vial adapter 30 includes a manually placed cap 42 for sealing the female Luer connector 41.


The top wall 32 includes a pair of diametrical opposite axial directed vent apertures 43. An annular air filter 44 is disposed beneath the top wall 32. The vent apertures 43 are in flow communication with the vent lumen 38 via the air filter 44. The air filter 44 filters air entering drawn into the vial 20 on puncturing the vial stopper 22.


The top wall 32 is formed with a pair of protective hoods 46 mounted over the vent apertures 43 for covering the vent apertures 43 in FIG. 2's top plan view. The protective hoods 46 are preferably quarter sphere shaped. The protective hoods 46 each have a hood aperture 47 above the top wall 32 and facing radial outwards relative to the longitudinal vial adapter axis 31. The protective hoods 46 preclude liquid contents inadvertently wetting the air filter 44 via the vent apertures 43 during use of the vial adapter 30.



FIG. 5 shows a U.S. Pat. No. 6,558,365 liquid drug transfer device 50 with a detachable vented vial adapter 51 similar to the vented vial adapter 30.


While the invention has been described with respect to a limited number of embodiments, it will be appreciated that many variations, modifications, and other applications of the invention can be made within the scope of the appended claims.

Claims
  • 1. A liquid drug transfer device for use with a medicinal vial including a bottle containing a medicament, a vial opening stopped by a vial stopper, and a narrow neck intermediate the bottle and the vial opening, the liquid drug transfer device comprising: a vented vial adapter having a longitudinal vial adapter axis and including a top wall transverse to said longitudinal adapter axis, a cylindrical skirt having flex members resiliently attached to said top wall and downwardly depending therefrom for telescopically slidingly receiving the vial opening therein, an annular air filter disposed beneath said top wall,said top wall having an upper surface and said cylindrical skirt having peripheral skirt surface, said upper surface meeting said peripheral skirt surface at an upper surface edge,a downwardly depending dual lumen puncturing spike for puncturing the vial stopper for establishing flow communication with the bottle interior said puncturing spike having a base adjacent said top wall and a puncturing tip, said puncturing tip including a pair of axial directed lumens extending from said base to said puncturing tip, said pair of axial directed lumens including a liquid transfer lumen and a vent lumen,a liquid transfer port in flow communication with said liquid transfer lumen, said liquid transfer port extending upwardly from said upper surface opposite said cylindrical skirt,at least two spaced apart axially directed vent apertures formed in said top wall and in flow communication with said vent lumen via said air filter,said liquid transfer port and said at least two spaced apart vent apertures being in flow communication with the bottle on slidingly receiving the vial in the vial adapter,wherein said top wall is formed with a corresponding number of at least two discrete protective hoods at said at least two vent apertures extending upwardly from said upper surface, opposite said cylindrical skirt, such that each of said at least two vent apertures is individually covered by a discrete protective hood in a top plan view of said vented vial adapter along said longitudinal vial adapter axis and each of said at least two discrete protective hoods (i) has a hood aperture facing radially outwardly with respect to said longitudinal vial adapter axis, and (ii) is visible in a side elevation view of said vented vial adapter intercepting said upper surface edge such that liquid contents inadvertently disposed on said upper surface of an inclined vented vial adapter are diverted around a discrete protective hood for draining over said upper surface edge and down said peripheral skirt surface, thereby inhibiting said inadvertently disposed liquid contents from inadvertently entering the corresponding vent aperture covered thereby and wetting said air filter.
  • 2. The device according to claim 1, wherein each said protective hood has a quarter sphere shaped protective hood.
  • 3. The device according to claim 1, further comprising a manually placed cap for sealing said liquid access port.
  • 4. A liquid drug transfer device for use with a medicinal vial including a bottle containing a medicament, a vial opening stopped by a vial stopper, and a narrow neck intermediate the bottle and the vial opening, the liquid drug transfer device comprising a vented vial adapter having a longitudinal vial adapter axis and including a top wall transverse to said longitudinal axis, a cylindrical skirt having flex members resiliently attached to said top wall and downwardly depending therefrom for telescopically slidingly receiving the vial opening therein, an annular air filter disposed beneath said top wall,a downwardly depending dual lumen puncturing spike for puncturing the vial stopper and establishing flow communication with the bottle interior, said puncturing spike having a base adjacent said top wall and a puncturing tip, said puncturing tip including a pair of axially directed lumens extending from said base to said puncturing tip, said pair of axially directed lumens including a liquid transfer lumen and a vent lumen,a liquid transfer port in flow communication with said liquid transfer lumen,at least one axially directed vent aperture formed in said top wall and in flow communication with said vent lumen via said air filter,said liquid transfer port and said at least one vent aperture being in flow communication with the bottle on slidingly receiving the vial in the vial adapterwherein said top wall is formed with a corresponding number of at least one quarter-sphere shaped protective hood at said at least one vent aperture, such that each of said at least one vent aperture is individually covered by a protective hood in a top plan view of said vented vial adapter along said longitudinal vial adapter axis and each of said at least one protective hood has a hood aperture facing-radially outwardly with respect to said longitudinal vial adapter axis.
  • 5. The device according to claim 4, further comprising a manually placed cap for sealing said liquid access port.
Priority Claims (2)
Number Date Country Kind
204141 Feb 2010 IL national
209101 Nov 2010 IL national
PCT Information
Filing Document Filing Date Country Kind 371c Date
PCT/IL2011/000187 2/23/2011 WO 00 8/1/2012
Publishing Document Publishing Date Country Kind
WO2011/104712 9/1/2011 WO A
US Referenced Citations (577)
Number Name Date Kind
62333 Holl Feb 1867 A
1021681 Jennings Mar 1912 A
1704817 Ayers Mar 1929 A
1930944 Schmitz, Jr. Oct 1933 A
2326490 Perelson Aug 1943 A
2931668 Baley Apr 1960 A
2968497 Treleman Jan 1961 A
3059643 Barton Oct 1962 A
D198499 Harautuneian Jun 1964 S
3484849 Huebner et al. Dec 1969 A
3618637 Santomieri Nov 1971 A
3757981 Harris, Sr. et al. Sep 1973 A
3788524 Davis et al. Jan 1974 A
3822700 Pennington Jul 1974 A
3826261 Killinger Jul 1974 A
3885607 Peltier May 1975 A
3938520 Scislowicz et al. Feb 1976 A
3957052 Topham May 1976 A
3977555 Larson Aug 1976 A
3993063 Larrabee Nov 1976 A
4020839 Klapp May 1977 A
4051852 Villari Oct 1977 A
4109670 Slagel Aug 1978 A
4121585 Becker, Jr. Oct 1978 A
4161178 Genese Jul 1979 A
4187848 Taylor Feb 1980 A
4203067 Fitzky et al. May 1980 A
4203443 Genese May 1980 A
4210173 Choksi et al. Jul 1980 A
D257286 Folkman Oct 1980 S
4253501 Ogle Mar 1981 A
4296786 Brignola Oct 1981 A
4303067 Connolly et al. Dec 1981 A
4312349 Cohen Jan 1982 A
4314586 Folkman Feb 1982 A
4328802 Curley et al. May 1982 A
4335717 Bujan et al. Jun 1982 A
D267199 Koenig Dec 1982 S
4376634 Prior et al. Mar 1983 A
D268871 Benham et al. May 1983 S
4392850 Elias et al. Jul 1983 A
4410321 Pearson et al. Oct 1983 A
4411662 Pearson Oct 1983 A
D271421 Fetterman Nov 1983 S
4434823 Hudspith Mar 1984 A
4465471 Harris et al. Aug 1984 A
4475915 Sloane Oct 1984 A
4493348 Lemmons Jan 1985 A
4505709 Froning et al. Mar 1985 A
4507113 Dunlap Mar 1985 A
D280018 Scott Aug 1985 S
4532969 Kwaan Aug 1985 A
4564054 Gustavsson Jan 1986 A
4573993 Hoag et al. Mar 1986 A
4576211 Valentini et al. Mar 1986 A
4581014 Millerd et al. Apr 1986 A
4588396 Stroebel et al. May 1986 A
4588403 Weiss et al. May 1986 A
D284603 Loignon Jul 1986 S
4604093 Brown et al. Aug 1986 A
4607671 Aalto et al. Aug 1986 A
4614437 Buehler Sep 1986 A
4638975 Iuchi et al. Jan 1987 A
4639019 Mittleman Jan 1987 A
4667927 Oscarsson May 1987 A
4676530 Nordgren et al. Jun 1987 A
4683975 Booth et al. Aug 1987 A
4697622 Swift et al. Oct 1987 A
4721133 Sundblom Jan 1988 A
4729401 Raines Mar 1988 A
4735608 Sardam Apr 1988 A
4743229 Chu May 1988 A
4743243 Vaillancourt May 1988 A
4752292 Lopez et al. Jun 1988 A
4758235 Tu Jul 1988 A
4759756 Forman et al. Jul 1988 A
4778447 Velde et al. Oct 1988 A
4787898 Raines Nov 1988 A
4797898 Martinez Jan 1989 A
4804366 Zdeb et al. Feb 1989 A
4832690 Kuu May 1989 A
4834152 Howson et al. May 1989 A
4857062 Russell Aug 1989 A
4865592 Rycroft Sep 1989 A
4909290 Coccia Mar 1990 A
4931040 Haber et al. Jun 1990 A
4932944 Jagger et al. Jun 1990 A
4967797 Manska Nov 1990 A
D314050 Sone Jan 1991 S
D314622 Andersson et al. Feb 1991 S
4997430 Van der Heiden et al. Mar 1991 A
5006114 Rogers et al. Apr 1991 A
5035686 Crittenden et al. Jul 1991 A
5041105 D'Alo et al. Aug 1991 A
5045066 Scheuble et al. Sep 1991 A
5049129 Zdeb et al. Sep 1991 A
5053015 Gross Oct 1991 A
5061248 Sacco Oct 1991 A
5088996 Kopfer et al. Feb 1992 A
5096575 Cosack Mar 1992 A
5104387 Pokorney et al. Apr 1992 A
5113904 Aslanian May 1992 A
5122124 Novacek et al. Jun 1992 A
5125908 Cohen Jun 1992 A
5125915 Berry et al. Jun 1992 A
D328788 Sagae et al. Aug 1992 S
5171230 Eland et al. Dec 1992 A
5201705 Berglund et al. Apr 1993 A
5201717 Wyatt et al. Apr 1993 A
5203771 Melker et al. Apr 1993 A
5203775 Frank et al. Apr 1993 A
5211638 Dudar et al. May 1993 A
5232029 Knox et al. Aug 1993 A
5232109 Tirrell et al. Aug 1993 A
5242432 DeFrank Sep 1993 A
5247972 Tetreault Sep 1993 A
D341420 Conn Nov 1993 S
5269768 Cheung Dec 1993 A
5270219 DeCastro et al. Dec 1993 A
5279576 Loo et al. Jan 1994 A
5288290 Brody Feb 1994 A
5300034 Behnke et al. Apr 1994 A
5304163 Bonnici et al. Apr 1994 A
5308483 Sklar et al. May 1994 A
5312377 Dalton May 1994 A
5328474 Raines Jul 1994 A
D349648 Tirrell et al. Aug 1994 S
5334163 Sinnett Aug 1994 A
5334179 Poli et al. Aug 1994 A
5342346 Honda et al. Aug 1994 A
5344417 Wadsworth, Jr. Sep 1994 A
5350372 Ikeda et al. Sep 1994 A
5364386 Fukuoka et al. Nov 1994 A
5364387 Sweeney Nov 1994 A
5374264 Wadsworth, Jr. Dec 1994 A
5385547 Wong et al. Jan 1995 A
5397303 Sancoff et al. Mar 1995 A
5429614 Fowles et al. Jul 1995 A
5433330 Yatsko et al. Jul 1995 A
5445630 Richmond Aug 1995 A
5445631 Uchida Aug 1995 A
5451374 Molina Sep 1995 A
5454805 Brony Oct 1995 A
5464111 Vacek et al. Nov 1995 A
5464123 Scarrow Nov 1995 A
5466219 Lynn et al. Nov 1995 A
5466220 Brenneman Nov 1995 A
5470327 Helgren et al. Nov 1995 A
5478337 Okamoto et al. Dec 1995 A
5492147 Challender et al. Feb 1996 A
D369406 Niedospial et al. Apr 1996 S
5505714 Dassa et al. Apr 1996 A
5509433 Paradis Apr 1996 A
5520659 Hedges May 1996 A
5526853 McPhee et al. Jun 1996 A
5527306 Haining Jun 1996 A
5531695 Swisher Jul 1996 A
5547471 Thompson et al. Aug 1996 A
5549577 Siegel et al. Aug 1996 A
5554128 Hedges Sep 1996 A
5566729 Grabenkort et al. Oct 1996 A
5569191 Meyer Oct 1996 A
5573281 Keller Nov 1996 A
5578015 Robb Nov 1996 A
5583052 Portnoff et al. Dec 1996 A
5584819 Kopfer Dec 1996 A
5591143 Trombley, III et al. Jan 1997 A
5603706 Wyatt et al. Feb 1997 A
5607439 Yoon Mar 1997 A
5611576 Guala Mar 1997 A
5616203 Stevens Apr 1997 A
5636660 Pfleiderer et al. Jun 1997 A
5641010 Maier Jun 1997 A
5645538 Richmond Jul 1997 A
5647845 Haber et al. Jul 1997 A
5651776 Appling et al. Jul 1997 A
5653686 Coulter et al. Aug 1997 A
5674195 Truthan Oct 1997 A
5676346 Leinsing Oct 1997 A
5685845 Grimard Nov 1997 A
5699821 Paradis Dec 1997 A
5702019 Grimard Dec 1997 A
5718346 Weiler Feb 1998 A
D393722 Fangrow, Jr. et al. Apr 1998 S
5738144 Rogers Apr 1998 A
5743312 Pfeifer et al. Apr 1998 A
5746733 Capaccio et al. May 1998 A
5755696 Caizza May 1998 A
5766211 Wood et al. Jun 1998 A
5772630 Ljungquist Jun 1998 A
5772652 Zielinski Jun 1998 A
RE35841 Frank et al. Jul 1998 E
5776116 Lopez et al. Jul 1998 A
5782872 Muller Jul 1998 A
5806831 Paradis Sep 1998 A
5817082 Niedospial, Jr. et al. Oct 1998 A
5820621 Yale et al. Oct 1998 A
5827262 Neftel et al. Oct 1998 A
5832971 Yale et al. Nov 1998 A
5833213 Ryan Nov 1998 A
5834744 Risman Nov 1998 A
5839715 Leinsing Nov 1998 A
5853406 Masuda et al. Dec 1998 A
5871110 Grimard et al. Feb 1999 A
5873872 Thibault et al. Feb 1999 A
5879337 Kuracina et al. Mar 1999 A
5879345 Aneas Mar 1999 A
5887633 Yale et al. Mar 1999 A
5890610 Jansen et al. Apr 1999 A
5891129 Daubert et al. Apr 1999 A
5893397 Peterson et al. Apr 1999 A
5897526 Vaillancourt Apr 1999 A
5899468 Apps et al. May 1999 A
5902280 Powles et al. May 1999 A
5902298 Niedospial, Jr. et al. May 1999 A
5911710 Barry et al. Jun 1999 A
5919182 Avallone Jul 1999 A
5921419 Niedospial, Jr. et al. Jul 1999 A
5924584 Hellstrom et al. Jul 1999 A
5925029 Jansen et al. Jul 1999 A
5935112 Stevens et al. Aug 1999 A
5941848 Nishimoto et al. Aug 1999 A
5944700 Nguyen et al. Aug 1999 A
5954104 Daubert et al. Sep 1999 A
5971181 Niedospial, Jr. et al. Oct 1999 A
5971965 Mayer Oct 1999 A
5989237 Fowles et al. Nov 1999 A
6003566 Thibault et al. Dec 1999 A
6004278 Botich et al. Dec 1999 A
6019750 Fowles et al. Feb 2000 A
6022339 Fowles et al. Feb 2000 A
6036171 Weinheimer et al. Mar 2000 A
6039093 Mrotzek et al. Mar 2000 A
6039302 Cote, Sr. et al. Mar 2000 A
D422357 Niedospial, Jr. et al. Apr 2000 S
6063068 Fowles et al. May 2000 A
D427308 Zinger Jun 2000 S
6070623 Aneas Jun 2000 A
6071270 Fowles et al. Jun 2000 A
6080132 Cole et al. Jun 2000 A
6089541 Weinheimer et al. Jul 2000 A
6090091 Fowles et al. Jul 2000 A
6090093 Thibault et al. Jul 2000 A
6099511 Devos et al. Aug 2000 A
6113068 Ryan Sep 2000 A
6113583 Fowles et al. Sep 2000 A
6117114 Paradis Sep 2000 A
6139534 Niedospial, Jr. et al. Oct 2000 A
6142446 Leinsing Nov 2000 A
6146362 Turnbull et al. Nov 2000 A
6156025 Niedospial, Jr. et al. Dec 2000 A
6159192 Fowles et al. Dec 2000 A
6168037 Grimard Jan 2001 B1
6171287 Lynn et al. Jan 2001 B1
6171293 Rowley et al. Jan 2001 B1
6173852 Browne Jan 2001 B1
6174304 Weston Jan 2001 B1
6179822 Niedospial, Jr. Jan 2001 B1
6179823 Niedospial, Jr. Jan 2001 B1
6206861 Mayer Mar 2001 B1
6221041 Russo Apr 2001 B1
6221054 Martin et al. Apr 2001 B1
6221065 Davis Apr 2001 B1
6238372 Zinger et al. May 2001 B1
6245044 Daw et al. Jun 2001 B1
D445501 Niedospial, Jr. Jul 2001 S
D445895 Svendsen Jul 2001 S
6253804 Safabash Jul 2001 B1
6258078 Thilly Jul 2001 B1
6280430 Neftel et al. Aug 2001 B1
6290688 Lopez et al. Sep 2001 B1
6296621 Masuda et al. Oct 2001 B1
6299131 Ryan Oct 2001 B1
6343629 Wessman et al. Feb 2002 B1
6348044 Coletti et al. Feb 2002 B1
6358236 DeFoggi et al. Mar 2002 B1
6364866 Furr et al. Apr 2002 B1
6378576 Thibault et al. Apr 2002 B2
6378714 Jansen et al. Apr 2002 B1
6379340 Zinger et al. Apr 2002 B1
6382442 Thibault et al. May 2002 B1
6408897 Laurent et al. Jun 2002 B1
6409708 Wessman Jun 2002 B1
6440107 Trombley, III et al. Aug 2002 B1
6453949 Chau Sep 2002 B1
6453956 Safabash Sep 2002 B2
6474375 Spero et al. Nov 2002 B2
6478788 Aneas Nov 2002 B1
D468015 Horppu Dec 2002 S
6499617 Niedospial, Jr. et al. Dec 2002 B1
6503240 Niedospial, Jr. et al. Jan 2003 B1
6503244 Hayman Jan 2003 B2
6520932 Taylor Feb 2003 B2
6524278 Campbell et al. Feb 2003 B1
6524295 Daubert et al. Feb 2003 B2
D472316 Douglas et al. Mar 2003 S
6530903 Wang et al. Mar 2003 B2
6537263 Aneas Mar 2003 B1
D472630 Douglas et al. Apr 2003 S
6544246 Niedospial, Jr. Apr 2003 B1
6551299 Miyoshi et al. Apr 2003 B2
6558365 Zinger et al. May 2003 B2
6571837 Jansen et al. Jun 2003 B2
6572591 Mayer Jun 2003 B2
6575955 Azzolini Jun 2003 B2
6581593 Rubin et al. Jun 2003 B1
6582415 Fowles et al. Jun 2003 B1
6591876 Safabash Jul 2003 B2
6601721 Jansen et al. Aug 2003 B2
6626309 Jansen et al. Sep 2003 B1
D482121 Harding et al. Nov 2003 S
D482447 Harding et al. Nov 2003 S
6651956 Miller Nov 2003 B2
6652509 Helgren et al. Nov 2003 B1
D483487 Harding et al. Dec 2003 S
D483869 Tran et al. Dec 2003 S
6656433 Sasso Dec 2003 B2
6666852 Niedospial, Jr. Dec 2003 B2
6681810 Weston Jan 2004 B2
6681946 Jansen et al. Jan 2004 B1
6682509 Lopez Jan 2004 B2
6692478 Paradis Feb 2004 B1
6692829 Stubler et al. Feb 2004 B2
6695829 Hellstrom et al. Feb 2004 B2
6699229 Zinger et al. Mar 2004 B2
6706022 Leinsing et al. Mar 2004 B1
6706031 Manera Mar 2004 B2
6715520 Andreasson et al. Apr 2004 B2
6729370 Norton et al. May 2004 B2
6736798 Ohkubo et al. May 2004 B2
6745998 Doyle Jun 2004 B2
6746438 Arnissolle Jun 2004 B1
6752180 Delay Jun 2004 B2
D495416 Dimeo et al. Aug 2004 S
D496457 Prais et al. Sep 2004 S
6802490 Leinsing et al. Oct 2004 B2
6832994 Niedospial, Jr. et al. Dec 2004 B2
6852103 Fuller et al. Feb 2005 B2
6875203 Fowles et al. Apr 2005 B1
6875205 Leinsing Apr 2005 B2
6878131 Novacek et al. Apr 2005 B2
6890328 Fowles et al. May 2005 B2
6901975 Aramata et al. Jun 2005 B2
6945417 Jansen et al. Sep 2005 B2
6948522 Newbrough et al. Sep 2005 B2
6949086 Ferguson et al. Sep 2005 B2
6957745 Thibault et al. Oct 2005 B2
RE38996 Crawford et al. Feb 2006 E
6994315 Ryan et al. Feb 2006 B2
6997916 Simas, Jr. et al. Feb 2006 B2
6997917 Niedospial, Jr. et al. Feb 2006 B2
7024968 Raudabough et al. Apr 2006 B2
7070589 Lolachi et al. Jul 2006 B2
7074216 Fowles et al. Jul 2006 B2
7083600 Meloul Aug 2006 B2
7086431 D'Antonio et al. Aug 2006 B2
7100890 Cote, Sr. et al. Sep 2006 B2
7150735 Hickle Dec 2006 B2
7192423 Wong Mar 2007 B2
7195623 Burroughs et al. Mar 2007 B2
7241285 Dikeman Jul 2007 B1
7294122 Kubo et al. Nov 2007 B2
7306199 Leinsing et al. Dec 2007 B2
D561348 Zinger et al. Feb 2008 S
7326188 Russell et al. Feb 2008 B1
7326194 Zinger et al. Feb 2008 B2
7350764 Raybuck Apr 2008 B2
7354422 Riesenberger et al. Apr 2008 B2
7354427 Fangrow Apr 2008 B2
7425209 Fowles et al. Sep 2008 B2
7435246 Zihlmann Oct 2008 B2
7452348 Hasegawa Nov 2008 B2
7470257 Norton et al. Dec 2008 B2
7470265 Brugger et al. Dec 2008 B2
7472932 Weber et al. Jan 2009 B2
7488297 Flaherty Feb 2009 B2
7491197 Jansen et al. Feb 2009 B2
7497848 Leinsing et al. Mar 2009 B2
7523967 Steppe Apr 2009 B2
7530546 Ryan et al. May 2009 B2
D595420 Suzuki et al. Jun 2009 S
D595421 Suzuki et al. Jun 2009 S
7540863 Haindl Jun 2009 B2
7540865 Griffin et al. Jun 2009 B2
7544191 Peluso et al. Jun 2009 B2
D595862 Suzuki et al. Jul 2009 S
D595863 Suzuki et al. Jul 2009 S
7611487 Woehr et al. Nov 2009 B2
7611502 Daly Nov 2009 B2
7615041 Sullivan et al. Nov 2009 B2
7628779 Aneas Dec 2009 B2
7632261 Zinger et al. Dec 2009 B2
D608900 Giraud et al. Jan 2010 S
7654995 Warren et al. Feb 2010 B2
7695445 Yuki Apr 2010 B2
D616090 Kawamura May 2010 S
7713247 Lopez May 2010 B2
7717886 Lopez May 2010 B2
7722090 Burton et al. May 2010 B2
D616984 Gilboa Jun 2010 S
7731678 Tennican et al. Jun 2010 B2
7743799 Mosler et al. Jun 2010 B2
7758082 Weigel et al. Jul 2010 B2
7762524 Cawthon et al. Jul 2010 B2
7766304 Phillips Aug 2010 B2
7771383 Truitt et al. Aug 2010 B2
7799009 Niedospial, Jr. et al. Sep 2010 B2
7803140 Fangrow, Jr. Sep 2010 B2
D627216 Fulginiti Nov 2010 S
D630732 Lev et al. Jan 2011 S
7862537 Zinger et al. Jan 2011 B2
7867215 Akerlund et al. Jan 2011 B2
7879018 Zinger et al. Feb 2011 B2
D634007 Zinger et al. Mar 2011 S
7900659 Whitley et al. Mar 2011 B2
D637713 Nord et al. May 2011 S
D644104 Maeda et al. Aug 2011 S
7993328 Whitley Aug 2011 B2
8016809 Zinger et al. Sep 2011 B2
8025653 Capitaine et al. Sep 2011 B2
8029472 Leinsing et al. Oct 2011 B2
8038123 Ruschke et al. Oct 2011 B2
8066688 Zinger et al. Nov 2011 B2
8070739 Zinger et al. Dec 2011 B2
8096525 Ryan Jan 2012 B2
8105314 Fangrow, Jr. Jan 2012 B2
D655017 Mosler et al. Feb 2012 S
8122923 Kraus et al. Feb 2012 B2
D655071 Davila Mar 2012 S
8157784 Rogers Apr 2012 B2
8167863 Yow May 2012 B2
8172824 Pfeifer et al. May 2012 B2
8177768 Leinsing May 2012 B2
8182452 Mansour et al. May 2012 B2
8197459 Jansen et al. Jun 2012 B2
8211069 Fangrow, Jr. Jul 2012 B2
8225959 Lambrecht Jul 2012 B2
8241268 Whitley Aug 2012 B2
8262628 Fangrow, Jr. Sep 2012 B2
D669980 Lev et al. Oct 2012 S
8287513 Ellstrom et al. Oct 2012 B2
D674088 Lev et al. Jan 2013 S
8480646 Nord et al. Jul 2013 B2
8506548 Okiyama Aug 2013 B2
8523837 Wiggins et al. Sep 2013 B2
8545476 Ariagno et al. Oct 2013 B2
8551067 Zinger et al. Oct 2013 B2
8556879 Okiyama Oct 2013 B2
20010000347 Hellstrom et al. Apr 2001 A1
20010025671 Safabash Oct 2001 A1
20010029360 Miyoshi et al. Oct 2001 A1
20010051793 Weston Dec 2001 A1
20020017328 Loo Feb 2002 A1
20020066715 Niedospial Jun 2002 A1
20020087118 Reynolds et al. Jul 2002 A1
20020087141 Zinger et al. Jul 2002 A1
20020087144 Zinger et al. Jul 2002 A1
20020121496 Thiebault et al. Sep 2002 A1
20020123736 Fowles et al. Sep 2002 A1
20020127150 Sasso Sep 2002 A1
20020128628 Fathallah Sep 2002 A1
20020173752 Polzin Nov 2002 A1
20020193777 Aneas Dec 2002 A1
20030028156 Juliar Feb 2003 A1
20030036725 Lavi et al. Feb 2003 A1
20030068354 Reif et al. Apr 2003 A1
20030073971 Saker Apr 2003 A1
20030100866 Reynolds May 2003 A1
20030120209 Jensen et al. Jun 2003 A1
20030153895 Leinsing Aug 2003 A1
20030187420 Akerlund et al. Oct 2003 A1
20030191445 Wallen et al. Oct 2003 A1
20030195479 Kuracina et al. Oct 2003 A1
20030199846 Fowles et al. Oct 2003 A1
20030199847 Akerlund et al. Oct 2003 A1
20040024354 Reynolds Feb 2004 A1
20040044327 Hasegawa Mar 2004 A1
20040073189 Wyatt et al. Apr 2004 A1
20040153047 Blank et al. Aug 2004 A1
20040181192 Cuppy Sep 2004 A1
20040204699 Hanly et al. Oct 2004 A1
20040217315 Doyle Nov 2004 A1
20040236305 Jansen et al. Nov 2004 A1
20050015070 Delnevo et al. Jan 2005 A1
20050055008 Paradis et al. Mar 2005 A1
20050124964 Niedospial et al. Jun 2005 A1
20050137566 Fowles et al. Jun 2005 A1
20050148994 Leinsing Jul 2005 A1
20050159724 Enerson Jul 2005 A1
20050182383 Wallen Aug 2005 A1
20050261637 Miller Nov 2005 A1
20060030832 Niedospial et al. Feb 2006 A1
20060079834 Tennican et al. Apr 2006 A1
20060089594 Landau Apr 2006 A1
20060089603 Truitt et al. Apr 2006 A1
20060095015 Hobbs et al. May 2006 A1
20060106360 Wong May 2006 A1
20060135948 Varma Jun 2006 A1
20060253084 Nordgren Nov 2006 A1
20070024995 Hayashi Feb 2007 A1
20070060904 Vedrine et al. Mar 2007 A1
20070079894 Kraus et al. Apr 2007 A1
20070083164 Barrelle et al. Apr 2007 A1
20070088252 Pestotnik et al. Apr 2007 A1
20070088293 Fangrow Apr 2007 A1
20070088313 Zinger et al. Apr 2007 A1
20070106244 Mosler et al. May 2007 A1
20070112324 Hamedi-Sangsari May 2007 A1
20070156112 Walsh Jul 2007 A1
20070167904 Zinger et al. Jul 2007 A1
20070191760 Iguchi et al. Aug 2007 A1
20070191764 Zihlmann Aug 2007 A1
20070191767 Hennessy et al. Aug 2007 A1
20070219483 Kitani et al. Sep 2007 A1
20070244461 Fangrow Oct 2007 A1
20070244462 Fangrow Oct 2007 A1
20070244463 Warren et al. Oct 2007 A1
20070249995 Van Manen Oct 2007 A1
20070255202 Kitani et al. Nov 2007 A1
20070265574 Tennican et al. Nov 2007 A1
20070265581 Funamura et al. Nov 2007 A1
20070270778 Zinger et al. Nov 2007 A9
20070287953 Ziv et al. Dec 2007 A1
20070299404 Katoh et al. Dec 2007 A1
20080009789 Zinger et al. Jan 2008 A1
20080009822 Enerson Jan 2008 A1
20080172024 Yow Jul 2008 A1
20080249479 Zinger et al. Oct 2008 A1
20080249498 Fangrow Oct 2008 A1
20080287905 Hiejima et al. Nov 2008 A1
20080294100 de Costa et al. Nov 2008 A1
20080306439 Nelson et al. Dec 2008 A1
20080312634 Helmerson et al. Dec 2008 A1
20090012492 Zihlmann Jan 2009 A1
20090082750 Denenburg et al. Mar 2009 A1
20090143758 Okiyama Jun 2009 A1
20090177177 Zinger et al. Jul 2009 A1
20090177178 Pedersen Jul 2009 A1
20090187140 Racz Jul 2009 A1
20090216212 Fangrow, Jr. Aug 2009 A1
20090267011 Hatton et al. Oct 2009 A1
20090299325 Vedrine et al. Dec 2009 A1
20090326506 Hasegawa et al. Dec 2009 A1
20100010443 Morgan et al. Jan 2010 A1
20100022985 Sullivan et al. Jan 2010 A1
20100030181 Helle et al. Feb 2010 A1
20100036319 Drake et al. Feb 2010 A1
20100076397 Reed et al. Mar 2010 A1
20100087786 Zinger et al. Apr 2010 A1
20100137827 Warren et al. Jun 2010 A1
20100168712 Tuckwell et al. Jul 2010 A1
20100179506 Shemesh et al. Jul 2010 A1
20100204670 Kraushaar et al. Aug 2010 A1
20100241088 Ranalletta et al. Sep 2010 A1
20100274184 Chun Oct 2010 A1
20100286661 Raday et al. Nov 2010 A1
20100312220 Kalitzki Dec 2010 A1
20110054440 Lewis Mar 2011 A1
20110224640 Kuhn et al. Sep 2011 A1
20110230856 Kyle et al. Sep 2011 A1
20110264069 Bochenko Oct 2011 A1
20110276007 Denenburg Nov 2011 A1
20110319827 Leinsing et al. Dec 2011 A1
20120022469 Alpert Jan 2012 A1
20120053555 Ariagno et al. Mar 2012 A1
20120059346 Sheppard et al. Mar 2012 A1
20120078214 Finke et al. Mar 2012 A1
20120123382 Kubo May 2012 A1
20120184938 Lev et al. Jul 2012 A1
20120215182 Mansour et al. Aug 2012 A1
20120220977 Yow Aug 2012 A1
20120220978 Lev et al. Aug 2012 A1
20120265163 Cheng et al. Oct 2012 A1
20120310203 Khaled et al. Dec 2012 A1
20130053814 Mueller-Beckhaus et al. Feb 2013 A1
20130096493 Kubo et al. Apr 2013 A1
20130199669 Moy et al. Aug 2013 A1
Foreign Referenced Citations (106)
Number Date Country
1913926 Sep 1970 DE
4122476 Jan 1993 DE
19504413 Aug 1996 DE
202004012714 Nov 2004 DE
202009011019 Dec 2010 DE
0192661 Sep 1986 EP
0195018 Sep 1986 EP
0258913 Mar 1988 EP
0416454 Mar 1991 EP
0518397 Dec 1992 EP
0521460 Jan 1993 EP
0637443 Feb 1995 EP
0737467 Oct 1996 EP
761562 Mar 1997 EP
765652 Apr 1997 EP
765853 Apr 1997 EP
0806597 Nov 1997 EP
0814866 Jan 1998 EP
829248 Mar 1998 EP
0856331 Aug 1998 EP
882441 Dec 1998 EP
897708 Feb 1999 EP
0898951 Mar 1999 EP
960616 Dec 1999 EP
1008337 Jun 2000 EP
1029526 Aug 2000 EP
1034809 Sep 2000 EP
1051988 Nov 2000 EP
1323403 Jul 2003 EP
1329210 Jul 2003 EP
1396250 Mar 2004 EP
1454609 Sep 2004 EP
1454650 Sep 2004 EP
1498097 Jan 2005 EP
1872824 Jan 2008 EP
1919432 May 2008 EP
1930038 Jun 2008 EP
2351548 Aug 2011 EP
2351549 Aug 2011 EP
2029242 Oct 1970 FR
2856660 Dec 2004 FR
2869795 Nov 2005 FR
2931363 Nov 2009 FR
1444210 Jul 1976 GB
171662 Oct 2005 IL
03-062426 Sep 1991 JP
4329954 Nov 1992 JP
06-050656 Jul 1994 JP
H08-000710 Jan 1996 JP
09-104460 Apr 1997 JP
09-104461 Apr 1997 JP
10-118158 May 1998 JP
H10-504736 May 1998 JP
11503627 Mar 1999 JP
11-319031 Nov 1999 JP
2000-508934 Jul 2000 JP
2000-237278 Sep 2000 JP
2001-505083 Apr 2001 JP
2002-035140 Feb 2002 JP
2002-516160 Jun 2002 JP
2002-355318 Dec 2002 JP
2003-033441 Feb 2003 JP
2003-102807 Apr 2003 JP
2004-097253 Apr 2004 JP
2004-522541 Jul 2004 JP
9403373 Feb 1994 WO
9507066 Mar 1995 WO
9600053 Jan 1996 WO
9629113 Sep 1996 WO
9736636 Oct 1997 WO
9832411 Jul 1998 WO
9837854 Sep 1998 WO
9961093 Dec 1999 WO
0128490 Apr 2001 WO
0130425 May 2001 WO
0132524 May 2001 WO
0160311 Aug 2001 WO
0191693 Dec 2001 WO
0209797 Feb 2002 WO
0236191 May 2002 WO
02089900 Nov 2002 WO
03051423 Jun 2003 WO
03079956 Oct 2003 WO
2004041148 May 2004 WO
2005002492 Jan 2005 WO
2005041846 May 2005 WO
2005105014 Nov 2005 WO
2006099441 Sep 2006 WO
2007015233 Feb 2007 WO
2007017868 Feb 2007 WO
2007052252 May 2007 WO
2007105221 Sep 2007 WO
2009026443 Feb 2009 WO
2009029010 Mar 2009 WO
2009038860 Mar 2009 WO
2009038860 Mar 2009 WO
2009040804 Apr 2009 WO
2009087572 Jul 2009 WO
2009093249 Jul 2009 WO
2009112489 Sep 2009 WO
2009146088 Dec 2009 WO
2011058545 May 2011 WO
2011058548 May 2011 WO
2011077434 Jun 2011 WO
2011104711 Sep 2011 WO
2012143921 Oct 2012 WO
Non-Patent Literature Citations (103)
Entry
Int'l Search Report issued Jan. 22, 2013 in Int'l Application No. PCT/IL2012/000354.
Int'l Search Report issued Mar. 18, 2013 in Int'l Application No. PCT/IL2012/050516.
Office Action issued Apr. 2, 2013 in U.S. Appl. No. 13/505,790.
Int'l Search Report and Written Opinion issued Mar. 6, 2012 in Int'l Application No. PCT/IL2011/000834.
U.S. Appl. No. 13/883,289 by Lev, filed May 3, 2013.
U.S. Appl. No. 29/438,134 by Lev, filed Nov. 27, 2012.
U.S. Appl. No. 29/438,141 by Gilboa, filed Nov. 27, 2012.
Int'l Search Report & Written Opinion issued on Mar. 7, 2012 in Int'l Application No. PCT/IL2011/000829.
U.S. Appl. No. 13/884,981 by Denenburg, filed May 13, 2013.
Office Action issued May 31, 2013 in U.S. Appl. No. 13/505,790.
Office Action issued Mar. 1, 2012 in JP Application No. 2007-510229.
Int'l Search Report issued Mar. 7, 2012 in Int'l Application No. PCT/IL2011/000829; Written Opinion.
Office Action issued Mar. 13, 2012 in CA Application No. 2,563,643.
Office Action issued Mar. 1, 2012 in CN Application No. 2008801108283.4.
Office Action issued Mar. 6, 2012 in U.S. Appl. No. 12/678,928.
Int'l Search Report issued Feb. 3, 2011 in Int'l Application No. PCT/IL2010/000777; Written Opinion.
Int'l Search Report issued Mar. 17, 2011 in Int'l Application No. PCT/IL2010/000854; Written Opinion.
Int'l Search Report issued Mar. 17, 2011 in Int'l Application No. PCT/IL2010/000915; Written Opinion.
U.S. Appl. No. 13/505,790 by Lev, filed May 3, 2012.
U.S. Appl. No. 13/505,881 by Lev, filed May 3, 2012.
U.S. Appl. No. 13/522,410 by Lev, filed Jul. 16, 2012.
Office Action issued Jun. 14, 2012 in U.S. Appl. No. 29/376,980.
Office Action issued Jun. 15, 2012 in U.S. Appl. No. 29/413,170.
Office Action issued Jun. 21, 2012 in U.S. Appl. No. 12/596,167.
Int'l Search Report issued Aug. 16, 2012 in Int'l Application No. PCT/IL2012/000164.
Int'l Search Report issued Jun. 19, 2013 in Int'l Application No. PCT/IL2013/050167.
Int'l Preliminary Report on Patentability issued Aug. 28, 2012 in Int'l Application No. PCT/IL2011/000186.
U.S. Appl. No. 14/005,751 by Denenburg, filed Sep. 17, 2013.
English translation of an Office Action issued Jul. 26, 2013 in JP Application No. 2012-538464.
International Search Report Issued Jan. 23, 2007 in Int'l Application No. PCT/IL/2006/001228.
IV disposables sets catalogue, Cardinal Health, Alaris® products, SmartSite® access devices and accessories product No. 10013365, SmartSite add-on bag access device with spike adapter and needle-free valve bag access port, pp. 1-5, Fall edition (2007).
Office Action Issued Jun. 8, 2010 in U.S. Appl. No. 12/112,490 by Zinger.
Office Action issued Sep. 28, 2010 in U.S. Appl. No. 12/112,490 by Zinger.
Article with picture of West Pharmaceutical Services' Vial2Bag Needleless System, [on-line]; ISIPS Newsletter, Oct. 26, 2007]; retrieved from Internet Feb. 16, 2010]; URL:<http://www.isips.org/reports/ISIPS—Newsletter—October—26—2007. html.> (7 pages. see pp. 5-6).
Office Action issued Jun. 15, 2011 in JP Application No. 2008-538492.
Translation of Office Action issued Jun. 18, 2012 in JP Application No. 2008-538492.
Translation of Office Action issued Apr. 15, 2013 in JP Application No. 2008-538492.
Office Action issued Jul. 13, 2012 in U.S. Appl. No. 12/112,490 by Zinger.
Office Action issued Jan. 23, 2013 in U.S. Appl. No. 12/112,490 by Zinger.
Int'l Preliminary Report on Patentability issued May 6, 2008 in Int'l Application No. PCT/IL2006/001228.
Grifols Vial Adapter Product Literature, 2 pages, Jan. 2002.
Novel Transfer, Mixing and Drug Delivery Systems, MOP Medimop Medical Projects Ltd. Catalog, 4 pages, Rev. 4, 2004.
Smart Site.RTM. Alaris Medical Systems Product Brochure, 4 pages, Issue 1, Oct. 1999.
Smart Site.RTM. Needle-Free Systems, Alaris Medical Systems Webpage, 4 pages, Feb. 2006.
Photographs of Alaris Medical Systems SmartSite.RTM. device, 5 pages, 2002.
Non-Vented Vial Access Pin with ultrasite.rtm. Valve, B. Braun Medical, Inc. website and product description, 3 pages, Feb. 2006.
Office Action Issued Oct. 6, 2003 in U.S. Appl. No. 10/062,796.
Office Action Issued Feb. 22, 2005 in U.S. Appl. No. 10/062,796.
Office Action Issued Oct. 5, 2005 in U.S. Appl. No. 10/062,796.
Office Action Issued Feb. 20, 2009 in U.S. Appl. No. 11/694,297.
Int'l Search Report Issued Dec. 6, 2006 in Int'l Application No. PCT/IL2006/000912.
Int'l Preliminary Report on Patentability Issued Dec. 4, 2007 in Int'l Application No. PCT/IL2006/000912.
http://www.westpharma.com/eu/en/products/Pages/Mixject.aspx, dated Aug. 8, 2012.
Int'l Search Report Issued Jul. 27, 2007 in Int'l Application No. PCT/IL2007/000343.
http://www.westpharma.com/eu/en/products/Pages/Mixject.aspx.
http://www.westpharma.com/eu/SiteCollectionDocuments/Recon/mixject%20product%20sheet.pfg; Mixject product information sheet pp. 1.
Int'l Preliminary Report on Patentability Issued Jun. 19, 2008 in Int'l Application No. PCT/IL2007/000343.
Int'l Search Report Issued Mar. 27, 2009 in Int'l Application No. PCT/US2008/070024.
Int'l Search Report Issued Oct. 17, 2005 in Int'l Application No. PCT/IL2005/000376.
Int'l Preliminary Report on Patentability Issued Jun. 19, 2006 in Int'l Application No. PCTT/IL2005/000376.
Written Opinion of ISR Issued in Int'l Application No. PCT/IL2005/000376, Issued Oct. 29, 2006.
Int'l Search Report Issued Aug. 25, 2008 in Int'l Application No. PCT/IL2008/000517.
Written Opinion of the ISR Issued Oct. 17, 2009 in Int'l Application No. PCT/IL08/00517.
Int'l Preliminary Report on Patenability Issued Oct. 20, 2009 in Int'l Application No. PCT/IL2008/000517.
Written Opinion of the Int'l Searching Authority Issued Oct. 27, 2008 in Int'l Application No. PCT/US2008/070024.
Int'l Search Report Issued Mar. 12, 2009 in Int'l Application No. PCT/IL2008/001278.
Office Action Issued Jan. 20, 2010 in JP Application No. 2007-510229.
Office Action Issued Apr. 20, 2010 in U.S. Appl. No. 11/997,569.
Int'l Search Report dated Nov. 20, 2006 in Int'l Application No. PCT/IL2006/000881.
Office Action Issued May 27, 2010 in U.S. Appl. No. 11/559,152.
Decision to Grant mailed Apr. 12, 2010 in EP Application No. 08738307.1.
Office Action issued Jun. 1, 2010 in U.S. Appl. No. 11/568,421.
Office Action issued Nov. 12, 2010 in U.S. Appl. No. 29/334,697.
The MixJect transfer system, as shown in the article, “Advanced Delivery Devices,” Drug Delivery Technology Jul./Aug. 2007 vol. 7 No. 7 [on-line]. [Retrieved from Internet May 14, 2010.] URL: <http://www.drugdeiverytech-online.com/drugdelivery/200707/?pg=28pg28>. (3 pages).
Publication date of Israeli Patent Application 186290 [on-line]. ]Retrieved from Internet May 24, 2010]. URL:<http://www.ilpatsearch.justrice.gov.il/UI/RequestsList.aspx>. (1 page).
Int'l Search Report issued Nov. 25, 2010 in Int'l Application No. PCT/IL2010/000530.
Office Action issued Feb. 7, 2011 in U.S. Appl. No. 12/783,194.
Office Action issued Dec. 20, 2010 in U.S. Appl. No. 12/063,176.
Office Action issued Dec. 13, 2010 in U.S. Appl. No. 12/293,122.
Office Action issued Nov. 29, 2010 in U.S. Appl. No. 11/568,421.
Office Action issued Dec. 23, 2010 in U.S. Appl. No. 29/334,696.
Int'l Search Report issued on Mar. 17, 2011 in Int'l Application No. PCT/IL2010/000854.
http://www.knovel.com/web/portal/browse/display?—EXT—KNOVEL—DISPLAY—bookid=1023&VerticalID=0 [retrieved on Feb. 9, 2011].
Int'l Search Report issued on Mar. 17, 2011 in Int'l Application No. PCT/IL2010/00915.
Office Action Issued May 12, 2011 in U.S. Appl. No. 12/063,176.
Office Action issued Jul. 11, 2011 in U.S. Appl. No. 12/293,122.
Int'l Search Report issued Jul. 12, 2011 in Int'l Application No. PCT/IL2011/000187.
Int'l Search Report issued Jul. 12, 2011 in Int'l Application No. PCT/IL2011/000186.
Office Action issued Aug. 3, 2011 in JP Application No. 2008-525719.
Int'l Search Report issued Oct. 7, 2011 in Int'l Application No. PCT/IL2011/000511.
Int'l Search Report issued Mar. 6, 2012 in Int'l Application No. PCT/IL2011/000834; Written Opinion.
Written Opinion issued Aug. 16, 2012 in Int'l Application No. PCT/IL2012/000164.
English translation of an Office Action issued Sep. 10, 2013 in JP Application No. 2012-554468.
Int'l Search Report issued Jun. 5, 2013 in Int'l Application No. PCT/IL2012/050407.
Int'l Search Report issued Jun. 19, 2013 in Int'l Application No. PCT/IL201/050167.
Int'l Search Report issued Jul. 1, 2013 in Int'l Application No. PCT/IL2013/050180.
Int'l Search Report issued Jul. 31, 2103 in Int'l Application No. PCT/IL2013/050313.
Int'l Search Report issued Jul. 26, 2013 in Int'l Application No. PCT/IL2013/050316.
English translation of an Office Action issued Jun. 19, 2013 in JP Application No. 2012-531551.
Office Action issued Nov. 11, 2013 in IL Application No. 218730.
U.S. Appl. No. 29/478,723 by Lev, filed Jan. 8, 2014.
U.S. Appl. No. 29/478,726 by Lev, filed Jan. 8, 2014.
Office Action issued Jan. 2, 2014 in U.S. Appl. No. 13/505,881 by Lev.
Related Publications (1)
Number Date Country
20130046269 A1 Feb 2013 US