This application claims the priority of Swiss patent application 1430/14, filed Sep. 22, 2014, the disclosure of which is incorporated herein by reference in its entirety.
The invention relates to a low-temperature storage device for storing a plurality of objects at a temperature of less than 0° C., in particular below −20° C., typically at approximately −80° C.
A device of this type is described in US 2003/0233842.
Storage devices of this type require sophisticated thermal and atmospheric insulation. In particular, warm air with comparatively high water content should be prevented from entering the storage chamber in order to avoid ice formation within the chamber.
This is particularly true for storage devices adapted to store objects at temperatures below −20° C., in particular at approximately −80° C.
On the other hand, many applications of such storage devices, in particular as used in laboratory automation, require the objects in the storage chamber to be accessible by means of an automated transport device, such as a robot.
The problem to be solved by the present invention is therefore to provide a storage device of this type that is efficiently accessible by means of an automatic transport device and that provides a good insulation of the storage chamber.
This problem is solved by the low-temperature storage-device of claim 1.
Accordingly, the low-temperature storage device comprises the following:
The transport device can be used to manipulate the objects. By pivoting its carriage about the second axis, it can be aligned along a desired direction where an object is to be received or deposited. By said carriage being displaceable along said second axis, it can be adjusted to a desired height where an object is to be received or deposited.
By providing the pivotal and/or displaceable carriage in addition to having a rotatable lock chamber, it becomes possible to quickly and easily adjust the position of manipulator. Due to its higher weight and potentially higher friction, such movements could not be easily carried out by the lock chamber alone.
Advantageously, the transport device is pivotal about as well as displaceable along the second axis.
Advantageously, the device further comprises, at said transfer location, a plurality of transfer storage locations, with each transfer storage location adapted to receive one of said objects. In this case, the carriage of the transport device can be pivotal about and/or displaceable along said second axis to be aligned with each of said transfer storage locations. In this case, several transfer storage locations can be handled by the transport device.
The device can also comprise an item picker at said transfer location. This item picker is equipped with
an item picker location for receiving an object and
a picker device for removing an individual item from a plurality of items in said object at said picker location or for adding an individual item to a plurality of items in said object at said picker location.
In this case, the carriage of the transport device is pivotal about and/or displaceable along said second axis to be aligned with said picker location. Hence, the transport device can also be adapted to exchange objects with such an item picker.
Advantageously, the transfer storage locations are arranged above or below said item picker in order to provide a compact arrangement of parts in the transfer location.
In yet another embodiment, the device can further comprise a transfer chamber receiving said transfer location. In this case, the refrigerator device is adapted and structured to cool said transfer chamber to a transfer temperature below 0° C., but above the storage temperature. By providing such a transfer chamber at a low temperature, the flux of humidity into the storage chamber can be reduced further. However, the temperature of the transfer chamber is above the one of the storage chamber, which allows to place cold-sensitive components therein and/or allows better access for users.
The transfer chamber can further receive a transfer device structured and adapted to transfer objects between a first and second object location. The carriage of the transport device is pivotal about and/or displaceable along the second axis to be aligned with said first object location and to reach an object in said first object location. The second object location is at an opening of a housing of the low-temperature storage device. This provides a path for moving objects between the storage chamber and the outside of the low-temperature storage device.
The present invention is advantageously used for storing laboratory objects, in particular microplates, such as multiwell plates or sample tube holders, having the standardized SBS footprint of 127.75×85.48 mm.
Other advantageous embodiments are listed in the dependent claims as well as in the description below.
The invention will be better understood and objects other than those set forth above will become apparent from the following detailed description thereof. Such description makes reference to the annexed drawings, wherein:
A “low-temperature storage device” is a storage device adapted to store objects at temperatures below 0° C., in particular below −20° C., advantageously between −90° C. and −60° C.
An “automated” transport device is a transport device structured and adapted to be controlled and operated electronically by means of a control unit performing autonomous operations.
Overview:
These components are described in more detail in the following.
Storage Chamber:
Storage chamber 1 comprises insulating walls 10 surrounding an inner space 11 having a substantially quadratic footprint. Inner space 11 receives a storage carousel 12 rotatable about a vertical carousel axis 13 (the “third axis” in the context of the claims).
Carousel 12 is arranged in suspended fashion in a frame 14. As schematically shown in
A carousel drive 17 is provided for rotating carousel 12 about carousel axis 13. Carousel drive 17 comprises a carousel motor 18 (see
Advantageously, carousel motor 18 is located in transfer chamber 2 in order to keep the temperature gradient over shaft 19 low.
In the embodiment shown, shaft 19 extends horizontally, i.e. perpendicularly to carousel axis 13, and it drives carousel 12 for rotation about carousel axis 13 by means of an angular gear 20. This design minimizes the height of the storage device.
Carousel 12 forms a plurality of carousel storage locations 21 (
Lock Chamber:
The design of lock chamber 4 is best seen in
Lock chamber 4 is basically arranged in insulating wall 10 of storage chamber 1. As shown in
An opening 29 is arranged in cylindrical housing 27. Opening 29 extends from the top of lock chamber 4 to its bottom and has uniform width along its whole height in order to allow the carriage of the transport device to operate at a wide range of vertical positions, as described below.
The interior of lock chamber 4 is divided along a plane 30 (
Thermal insulator 34, which can e.g. be a vacuum insulator, has a maximum thickness at a location opposite opening 29. It reduces the thermal losses from lock chamber 1 through lock chamber 4. Advantageously, the maximum radial thickness (“radial” in respect to lock chamber axis 25) of thermal insulator 34 is at least 50% of the radius of cylindrical housing 27.
Transport Device:
Transport device 3 is, as mentioned, arranged within second section 32 of lock chamber 4. Its design can best be seen in
As can be seen from
Carriage 38 carries a manipulator 45, whose purpose is to hold the objects to be manipulated. In the shown embodiment, manipulator 45 is formed by a shovel-like table, which can be extended below an object to be picked up and then lifted to engage the object. Other manipulator designs, such as grippers or clamps, are known to the skilled person.
Manipulator 45 has a retracted and an extended position, and it can be extended, in respect to carriage 38, in horizontal direction from its retracted to its extended position in order to pick up or deposit an object. This displacement is achieved by means of a horizontal displacement motor 47.
Pivot axis 41 extends parallel to lock chamber axis 25. However, pivot axis 41 is advantageously located closer to opening 29 than lock chamber axis 25 in order to provide space for thermal insulator 34 and also in order to have manipulator 45 closer to the locations where the objects are stored.
When handling objects in transfer chamber 2, lock chamber 4 is rotated to a first position, as shown in
Carriage 38 has at least a first pivotal position 51a, which is shown in solid lines in
From its first pivotal position 51a, carriage 38 can be pivoted about pivot axis 41 into at least one second pivotal position (two such pivotal positions 51b, 51c are shown in
In order to take up an object, manipulator 45 is brought into its extended position and inserted below the object, then it moved upwards by a small distance to engage the object, whereupon it can be moved by to its retracted position.
While rotating lock chamber 4 about its lock chamber axis 25, manipulator 45 is in its retracted position and pivoted into its first pivotal position 51a.
When handling objects in storage chamber 1, lock chamber 4 is rotated to a second rotational position, as shown in
Transfer Chamber:
As mentioned, transfer chamber 2 holds a transfer location 50, where objects to be accessed by transport device 3 are located.
Advantageously, transfer location 50 forms a plurality of locations 55a-55d adapted to receive objects, as shown in
In the embodiments of
In the embodiment of
Item picker 60 comprises an item picker location 55b for receiving one object from transport device 3. This is e.g. a holder adapted to receive a single plate in SBS format.
Item picker 60 further comprises a picker device 62, which is adapted for removing an individual item from the plurality of items in the object at picker location 55b and/or for adding an individual item to the plurality of items in the object at picker location 55b.
In the embodiment of
Item picker 60 is arranged vertically above (or below) the storage locations 55a. Carriage 38 of transport device 3 can be vertically displaced and pivoted for being aligned with picker location 55b or one of the storage locations 55a.
In the embodiments of
First object location 71a forms one of the object locations that can be reached by the manipulator 45 of the transport device. Carriage 38 can be pivoted and vertically displaced for aligning manipulator 45 with first object location 71a. First object location 71a is located below (or above) the transfer storage locations 55a.
Second object location 71b is located at an opening 74 of an exterior housing 80 of the present storage device (see
Scanner 76 is used to scan markings on the objects and/or on items held by the objects.
Exterior Design:
As already mentioned and as shown in
A first door 81 is provided at the wall of storage chamber 1 and provides access to the interior of storage chamber 1. This door remains typically closed when the storage device is in use, but it may be opened for major service and maintenance.
A second door 82 is provided at the wall of transfer chamber 2 and provides user access to the components within access chamber 2.
A third door 83, which is smaller than second door 82, is also provided at the wall of transfer chamber 2 to cover opening 74, through which objects can be accessed at second object location 71b (see
Refrigerator Device:
As mentioned, the present storage device comprises a refrigerator device 5 for maintaining the temperatures within storage chamber 1 and transfer chamber 2.
An advantageous embodiment of such a device is shown in
First heat pump 90 is structured and adapted to pump heat from transfer chamber 2 to the environment. For this purpose, evaporator 94 is in thermal contact with transfer chamber 2 and condenser 92 is in thermal contact with the environment.
Second heat pump 91 is structured and adapted to pump heat from storage chamber 1 to evaporator 94 of first heat pump 90. In other words, the heat pumps 90, 91 are thermally arranged in series. For this purpose, evaporator 98 of second heat pump 91 is in thermal contact with storage chamber 1, condenser 96 of second heat pump 91 is in thermal contact with evaporator 94 of first heat pump 90, and evaporator 98 of second heat pump is in thermal contact with storage chamber 1.
This design with two heat pumps arranged “in series” and the first heat pump also being used to cool transfer chamber 2 provides a high level of efficiency.
Notes:
In the embodiment shown above, storage chamber 1 holds a single carousel and has substantially quadratic footprint. Alternatively, storage chamber 1 can e.g. be of rectangular footprint and hold two carousels side-by-side, or the carousel can be replaced with some other type of apparatus suitable for storing the objects.
In the example above, carriage 38 is pivotal as well as vertically displaceable. However, depending on its application, it could also only be pivotal or only be vertically displaceable.
Advantageously, transfer location 50 is located in transfer chamber 2. This allows to maintain transfer location 50 at a temperature below 0° C. and at low humidity, thereby reducing the amount of moisture passing into storage chamber 1 during operation of transport device 3. However, in an alternative embodiment, transfer chamber 2 can be dispensed with—in this case, transfer location 50 is located e.g. outside the outer housing of the storage device.
While there are shown and described presently preferred embodiments of the invention, it is to be distinctly understood that the invention is not limited thereto but may be otherwise variously embodied and practiced within the scope of the following claims.
Number | Date | Country | Kind |
---|---|---|---|
1430/14 | Sep 2014 | CH | national |
Number | Name | Date | Kind |
---|---|---|---|
3272579 | Leonard | Sep 1966 | A |
3782133 | Desperier et al. | Jan 1974 | A |
4250266 | Wade | Feb 1981 | A |
4907889 | Simone | Mar 1990 | A |
4981409 | Hirose et al. | Mar 1991 | A |
5224415 | McFadden | Jul 1993 | A |
5233844 | Knippscheer et al. | Aug 1993 | A |
5345395 | Griner | Sep 1994 | A |
5365980 | Deberardinis | Nov 1994 | A |
5449229 | Aschenbrenner et al. | Sep 1995 | A |
5735587 | Malin et al. | Apr 1998 | A |
5921102 | Vago | Jul 1999 | A |
6059507 | Adams | May 2000 | A |
6068393 | Hutchins et al. | May 2000 | A |
6129428 | Helwig et al. | Oct 2000 | A |
6357983 | Junca | Mar 2002 | B1 |
6478524 | Malin | Nov 2002 | B1 |
6568770 | Gonska et al. | May 2003 | B2 |
6581395 | Felder | Jun 2003 | B2 |
6673595 | Barbera-Guillem | Jan 2004 | B2 |
6694767 | Junca et al. | Feb 2004 | B2 |
7544329 | Malin | Jun 2009 | B2 |
20010043031 | Gonska et al. | Nov 2001 | A1 |
20030196446 | Sands | Oct 2003 | A1 |
20030233842 | Junca et al. | Dec 2003 | A1 |
20040115101 | Malin | Jun 2004 | A1 |
20040213651 | Malin | Oct 2004 | A1 |
20060150659 | Sidor | Jul 2006 | A1 |
20060156753 | Fuhr et al. | Jul 2006 | A1 |
20080231152 | Malin | Sep 2008 | A1 |
20090175763 | Malin | Jul 2009 | A1 |
20090188272 | Cloutier | Jul 2009 | A1 |
20100183408 | Malin | Jul 2010 | A1 |
20100275636 | Yoshimura et al. | Nov 2010 | A1 |
20110183411 | Nichols | Jul 2011 | A1 |
20120060520 | Collins | Mar 2012 | A1 |
20120134898 | Malin | May 2012 | A1 |
20140190977 | Malin | Jul 2014 | A1 |
Number | Date | Country |
---|---|---|
2 254 218 | Nov 1972 | DE |
0 725 133 | Aug 1996 | EP |
2005-143873 | Jun 2005 | JP |
9805753 | Feb 1998 | WO |
Entry |
---|
European Search Report conducted in counterpart Europe Appln. No. 15 002 719.1-1605 (Mar. 14, 2016). |
Number | Date | Country | |
---|---|---|---|
20160084564 A1 | Mar 2016 | US |