Claims
- 1. A method of stimulating the growth of lung alveolar surface in a lung in need thereof, comprising:
providing progenitor or stem cells capable of regenerating lung alveolar surface; and administering said progenitor or stem cells to said lung in an amount sufficient to stimulate the growth of lung alveolar surface therein.
- 2. A method according to claim 1, wherein said lung is in vivo in a subject in need of said treatment.
- 3. A method according to claim 1, wherein said lung is ex vivo, and wherein said administering step is followed by the step of:
transplanting said lung into a recipient in need thereof.
- 4. A method according to claim 1, wherein said subject is a mammalian subject.
- 5. A method according to claim 1, wherein said subject is a human subject.
- 6. A method according to claim 1, wherein said step or progenitor cells are from the same species as said subject.
- 7. A method according to claim 1, wherein said progenitor cells are autologous cells.
- 8. A method according to claim 1, wherein said administering step is carried out by intravenous injection, intra-arterial injection, or intra-bronchial administration.
- 9. A method according to claim 1, wherein said stem or progenitor cells are lung cells.
- 10. A method according to claim 1, wherein said stem or progenitor cells are bone marrow cells.
- 11. A method according to claim 1, wherein said stem or progenitor cells are embryonic stem cells.
- 12. A method according to claim 11, wherein said embryonic stem cells contain a cell nucleus that is autologous to said subject.
RELATED APPLICATIONS
[0001] This application claims the benefit of commonly owned, copending provisional patent application Serial No. 60/169,545, filed Dec. 7, 1999, the disclosure of which is incorporated by reference herein in its entirety.
GOVERNMENT SUPPORT
[0002] This invention was made with Government support under Grant Nos. HL44060, HL60231 and HL44977 from the National Institutes of Health. The U.S. Government has certain rights to this invention.
Provisional Applications (1)
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Number |
Date |
Country |
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60169545 |
Dec 1999 |
US |