The present invention relates to a machine for metering microtablets.
In recent times, pharmaceuticals are produced for consumption by patients in the form of capsules containing a given volume of microtablets comprising the active principle. It is obviously essential, therefore, when filling the capsules, that each be filled with exactly the desired volume of microtablets.
The microtablets are normally minute cylinders roughly 2 mm in diameter and 2 mm high.
The inaccuracy with which the microtablets are deposited inside the capsules is mainly caused by the generation of electrostatic forces, which cause the microtablets to form into clusters, a phenomenon which seriously impairs automatic filling of the capsules and, hence, output.
It is an object of the present invention to provide a capsule-filling machine designed to eliminate the drawbacks of the known art.
According to the present invention, there is provided a machine for metering microtablets into capsules; said machine being characterized by comprising a metering surface subjected to vibration and to rotation about a respective perpendicular axis; there being formed in said metering surface a number of sloping surfaces, along which said microtablets travel upwards, and a respective number of pockets, each for receiving the microtablets from a respective sloping surface; each of said pockets comprising a bottom wall movable between a fully-closed position, in which the microtablets are retained inside the respective pocket, and a fully-open position, in which the microtablets are unloaded.
In a preferred embodiment, the metering machine according to the present invention comprises blow-off means for cutting off flow of the microtablets into a pocket.
In another preferred embodiment, the metering machine according to the present invention comprises a cam member for controlling the movement of said bottom walls of said pockets.
A non-limiting embodiment of the invention will be described by way of example with reference to the accompanying drawings, in which:
Number 1 in
Machine 1 comprises a cylindrical vibrating base 2, and a number of vibrators 3 (only two shown in
In other words, vibrating base 2 is vibrated by vibrators 3, and is rotated about its axis of symmetry A by rotating shaft 6.
Machine 1 also comprises a circular metering surface 8, which is fixed to a top surface 2b of vibrating base 2, so as to be subjected to the same rotation and vibration as vibrating base 2.
As shown in
A microtablet deposited on top surface 8a of metering surface 8 is therefore forced upwards along a sloping surface 9 by vibration of metering surface 8, and, on reaching the end of sloping surface 9, crosses over top end 9a and drops into respective pocket 10.
Each pocket 10 comprises a bottom wall 11 movable between a fully-closed position, in which the microtablets are retained inside pocket 10, and a fully-open position, in which the microtablets inside pocket 10 are unloaded into a bottom shell of a capsule, as described below. Each bottom wall 11 is maintained, at rest, in the fully-closed position by a known torsion spring (not shown).
A number of holes 13 are formed in a raised edge 12 of peripheral portion 8b, and are each located at the top end 9a of a respective sloping surface 9. As described below, air is blown consecutively through holes 13 to cut off flow of the microtablets across end 9a.
Machine 1 comprises a microtablet unloading device 14 fixed with respect to and cooperating with metering surface 8 to unload the microtablets. In other words, being stationary as metering surface 8 rotates, unloading device 14 interacts consecutively with all the pockets 10 on metering surface 8.
Unloading device 14 comprises a cam member 15, which cooperates with bottom walls 11 of pockets 10 to open the bottom walls and so unload the microtablets; an air outlet 16, which blows air consecutively through holes 13 to prevent more than the predetermined number of microtablets from being deposited inside the pockets; a supporting plate 17 (shown in
In actual use, the microtablets are deposited on metering surface 8 rotating about respective axis A, and are forced, by vibration of metering surface 8, towards peripheral portion 8b and up along the various sloping surfaces 9, where they drop into respective pockets 10. Machine 1 is so timed that, by the time a specific pocket 10a contains the desired volume of microtablets, the pocket 10a is located at unloading device 14, as shown in
The machine according to the present invention clearly has the advantage of metering the microtablets accurately into the capsules, and so preventing other than the predetermined volume of microtablets from being deposited in each capsule. More specifically, the vibratory movement and the compulsory upward travel of the microtablets prevent clustering phenomena caused by electrostatic forces generated between the microtablets.
Moreover, the blow-off means further ensure the exact volume of microtablets inside the capsules.
One variation of the machine as described above comprises a sensor for each sloping surface. The sensor counts the number of microtablets deposited inside the respective pocket and activates the blow-off means, which, in this case, are fixed to the metering surface as opposed to forming part of the unloading device.
Number | Date | Country | Kind |
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B02005A0791 | Dec 2005 | IT | national |
Number | Name | Date | Kind |
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3986534 | Schmidt | Oct 1976 | A |
4070248 | Schmidt | Jan 1978 | A |
6814111 | Oliverio et al. | Nov 2004 | B1 |
6901972 | Nelson | Jun 2005 | B1 |
Number | Date | Country | |
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20070144674 A1 | Jun 2007 | US |